James Dennis - Publications

Affiliations: 
Molecular Genetics University of Toronto, Samuel Lunenfeld Research Institute 
Area:
Glycosylation
Website:
http://www.lunenfeld.ca/researchers/dennis

43 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2017 Veyhl J, Dunn RJ, Johnston WL, Bennett A, Zhang LW, Dennis JW, Schachter H, Culotti JG. The directed migration of gonadal distal tip cells in Caenorhabditis elegans requires NGAT-1, a ß1,4-N-acetylgalactosaminyltransferase enzyme. Plos One. 12: e0183049. PMID 28817611 DOI: 10.1371/Journal.Pone.0183049  0.656
2016 Lai J, Swystun LL, Cartier D, Zhang C, Nesbitt K, Dennis J, Hough C, Lillicrap D. Differential Glycosylation Between Recombinant Factor VIII Produced in Baby Hamster Kidney and Chinese Hamster Ovary Cells Confers Differences in Immunogenicity in a Humanized Hemophilia Α Mouse Model Blood. 128: 326-326. DOI: 10.1182/Blood.V128.22.326.326  0.343
2014 Soliman MA, Abdel Rahman AM, Lamming DW, Lamming DA, Birsoy K, Pawling J, Frigolet ME, Lu H, Fantus IG, Pasculescu A, Zheng Y, Sabatini DM, Dennis JW, Pawson T. The adaptor protein p66Shc inhibits mTOR-dependent anabolic metabolism. Science Signaling. 7: ra17. PMID 24550542 DOI: 10.1126/Scisignal.2004785  0.499
2014 Soliman MA, Abdel Rahman AM, Lamming DW, Birsoy K, Pawling J, Frigolet ME, Lu H, Fantus IG, Pasculescu A, Zheng Y, Sabatini DM, Dennis JW, Pawson T. A correction to the research article titled: "The adaptor protein p66Shc inhibits mTOR-dependent anabolic metabolism" (Science Signaling (2014)) Science Signaling. 7. DOI: 10.1126/scisignal.7315er2  0.474
2014 Dennis JW, Soliman MA, VanHook AM. Science Signaling Podcast: 18 February 2014 Science Signaling. 7: pc6-pc6. DOI: 10.1126/Scisignal.2005151  0.487
2013 Zheng Y, Zhang C, Croucher DR, Soliman MA, St-Denis N, Pasculescu A, Taylor L, Tate SA, Hardy WR, Colwill K, Dai AY, Bagshaw R, Dennis JW, Gingras AC, Daly RJ, et al. Temporal regulation of EGF signalling networks by the scaffold protein Shc1. Nature. 499: 166-71. PMID 23846654 DOI: 10.1038/Nature12308  0.514
2012 Beheshti Zavareh R, Sukhai MA, Hurren R, Gronda M, Wang X, Simpson CD, Maclean N, Zih F, Ketela T, Swallow CJ, Moffat J, Rose DR, Schachter H, Schimmer AD, Dennis JW. Suppression of cancer progression by MGAT1 shRNA knockdown. Plos One. 7: e43721. PMID 22957033 DOI: 10.1371/Journal.Pone.0043721  0.706
2012 Boscher C, Zheng YZ, Lakshminarayan R, Johannes L, Dennis JW, Foster LJ, Nabi IR. Galectin-3 protein regulates mobility of N-cadherin and GM1 ganglioside at cell-cell junctions of mammary carcinoma cells. The Journal of Biological Chemistry. 287: 32940-52. PMID 22846995 DOI: 10.1074/jbc.M112.353334  0.301
2008 Lau KS, Dennis JW. N-Glycans in cancer progression. Glycobiology. 18: 750-60. PMID 18701722 DOI: 10.1093/glycob/cwn071  0.39
2008 Beheshti Zavareh R, Lau KS, Hurren R, Datti A, Ashline DJ, Gronda M, Cheung P, Simpson CD, Liu W, Wasylishen AR, Boutros PC, Shi H, Vengopal A, Jurisica I, Penn LZ, ... ... Dennis JW, et al. Inhibition of the sodium/potassium ATPase impairs N-glycan expression and function. Cancer Research. 68: 6688-97. PMID 18701493 DOI: 10.1158/0008-5472.Can-07-6833  0.701
2008 Lau KS, Khan S, Dennis JW. Genome-scale identification of UDP-GlcNAc-dependent pathways. Proteomics. 8: 3294-302. PMID 18646010 DOI: 10.1002/pmic.200800208  0.346
2008 Xu GW, Mawji IA, Macrae CJ, Koch CA, Datti A, Wrana JL, Dennis JW, Schimmer AD. A high-content chemical screen identifies ellipticine as a modulator of p53 nuclear localization. Apoptosis : An International Journal On Programmed Cell Death. 13: 413-22. PMID 18181020 DOI: 10.1007/s10495-007-0175-4  0.388
2007 Mendelsohn R, Cheung P, Berger L, Partridge E, Lau K, Datti A, Pawling J, Dennis JW. Complex N-glycan and metabolic control in tumor cells. Cancer Research. 67: 9771-80. PMID 17942907 DOI: 10.1158/0008-5472.CAN-06-4580  0.438
2007 Cheung P, Pawling J, Partridge EA, Sukhu B, Grynpas M, Dennis JW. Metabolic homeostasis and tissue renewal are dependent on beta1,6GlcNAc-branched N-glycans. Glycobiology. 17: 828-37. PMID 17483135 DOI: 10.1093/Glycob/Cwm048  0.462
2007 Cheung P, Dennis JW. Mgat5 and Pten interact to regulate cell growth and polarity. Glycobiology. 17: 767-73. PMID 17400585 DOI: 10.1093/glycob/cwm037  0.405
2007 Chen X, Song IH, Dennis JE, Greenfield EM. Endogenous PKI gamma limits the duration of the anti-apoptotic effects of PTH and beta-adrenergic agonists in osteoblasts. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 22: 656-64. PMID 17266398 DOI: 10.1359/Jbmr.070122  0.323
2006 Partridge EA, Cheung P, Dennis JW. Cytokine sensitivity and N-glycan processing mutations. Methods in Enzymology. 417: 3-11. PMID 17132493 DOI: 10.1016/S0076-6879(06)17001-9  0.415
2006 Park HJ, Partridge E, Cheung P, Pawling J, Donovan R, Wrana JL, Dennis JW. Chemical enhancers of cytokine signaling that suppress microfilament turnover and tumor cell growth. Cancer Research. 66: 3558-66. PMID 16585180 DOI: 10.1158/0008-5472.CAN-05-2542  0.42
2006 Lagana A, Goetz JG, Cheung P, Raz A, Dennis JW, Nabi IR. Galectin binding to Mgat5-modified N-glycans regulates fibronectin matrix remodeling in tumor cells. Molecular and Cellular Biology. 26: 3181-93. PMID 16581792 DOI: 10.1128/MCB.26.8.3181-3193.2006  0.338
2005 Rittenberg B, Partridge E, Baker G, Clokie C, Zohar R, Dennis JW, Tenenbaum HC. Regulation of BMP-induced ectopic bone formation by Ahsg. Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. 23: 653-62. PMID 15885488 DOI: 10.1016/j.orthres.2004.11.010  0.327
2004 Partridge EA, Le Roy C, Di Guglielmo GM, Pawling J, Cheung P, Granovsky M, Nabi IR, Wrana JL, Dennis JW. Regulation of cytokine receptors by Golgi N-glycan processing and endocytosis. Science (New York, N.Y.). 306: 120-4. PMID 15459394 DOI: 10.1126/science.1102109  0.362
2004 Swallow CJ, Partridge EA, Macmillan JC, Tajirian T, DiGuglielmo GM, Hay K, Szweras M, Jahnen-Dechent W, Wrana JL, Redston M, Gallinger S, Dennis JW. alpha2HS-glycoprotein, an antagonist of transforming growth factor beta in vivo, inhibits intestinal tumor progression. Cancer Research. 64: 6402-9. PMID 15374947 DOI: 10.1158/0008-5472.Can-04-1117  0.715
2003 Ning Q, Berger L, Luo X, Yan W, Gong F, Dennis J, Levy G. STAT1 and STAT3 alpha/beta splice form activation predicts host responses in mouse hepatitis virus type 3 infection. Journal of Medical Virology. 69: 306-12. PMID 12526039 DOI: 10.1002/Jmv.10290  0.367
2003 Rittenberg B, Clokie C, Baker G, Tenenbaum H, Dennis J. BMP-induced heterotopic bone formation in fetuin-deficient mice Journal of Oral and Maxillofacial Surgery. 61: 40a-41. DOI: 10.1016/S0278-2391(03)00533-0  0.346
2002 Dennis JW, Pawling J, Cheung P, Partridge E, Demetriou M. UDP-N-acetylglucosamine:alpha-6-D-mannoside beta1,6 N-acetylglucosaminyltransferase V (Mgat5) deficient mice. Biochimica Et Biophysica Acta. 1573: 414-22. PMID 12417426 DOI: 10.1016/S0304-4165(02)00411-7  0.319
2002 Szweras M, Liu D, Partridge EA, Pawling J, Sukhu B, Clokie C, Jahnen-Dechent W, Tenenbaum HC, Swallow CJ, Grynpas MD, Dennis JW. alpha 2-HS glycoprotein/fetuin, a transforming growth factor-beta/bone morphogenetic protein antagonist, regulates postnatal bone growth and remodeling. The Journal of Biological Chemistry. 277: 19991-7. PMID 11901155 DOI: 10.1074/Jbc.M112234200  0.706
2000 Tajirian T, Dennis JW, Swallow CJ. Regulation of human monocyte proMMP-9 production by fetuin, an endogenous TGF-beta antagonist. Journal of Cellular Physiology. 185: 174-83. PMID 11025439 DOI: 10.1002/1097-4652(200011)185:2<174::AID-JCP2>3.0.CO;2-X  0.325
2000 Datti A, Donovan RS, Korczak B, Dennis JW. A homogeneous cell-based assay to identify N-linked carbohydrate processing inhibitors. Analytical Biochemistry. 280: 137-42. PMID 10805531 DOI: 10.1006/abio.2000.4506  0.341
2000 Granovsky M, Fata J, Pawling J, Muller WJ, Khokha R, Dennis JW. Suppression of tumor growth and metastasis in Mgat5-deficient mice. Nature Medicine. 6: 306-12. PMID 10700233 DOI: 10.1038/73163  0.362
1999 Dennis JW, Granovsky M, Warren CE. Glycoprotein glycosylation and cancer progression Biochimica Et Biophysica Acta - General Subjects. 1473: 21-34. PMID 10580127 DOI: 10.1016/S0304-4165(99)00167-1  0.321
1999 Binkert C, Demetriou M, Sukhu B, Szweras M, Tenenbaum HC, Dennis JW. Regulation of osteogenesis by fetuin. The Journal of Biological Chemistry. 274: 28514-20. PMID 10497215 DOI: 10.1074/Jbc.274.40.28514  0.709
1996 Demetriou M, Binkert C, Sukhu B, Tenenbaum HC, Dennis JW. Fetuin/alpha2-HS glycoprotein is a transforming growth factor-beta type II receptor mimic and cytokine antagonist. The Journal of Biological Chemistry. 271: 12755-61. PMID 8662721 DOI: 10.1074/Jbc.271.22.12755  0.39
1995 Korczak B, Goss P, Fernandez B, Baker M, Dennis JW. Branching N-linked oligosaccharides in breast cancer. Advances in Experimental Medicine and Biology. 353: 95-104. PMID 7985545 DOI: 10.1007/978-1-4615-2443-4_10  0.305
1995 Takano R, Muchmore E, Dennis JW. Sialylation and malignant potential in tumour cell glycosylation mutants. Glycobiology. 4: 665-74. PMID 7881181 DOI: 10.1093/glycob/4.5.665  0.332
1995 Demetriou M, Nabi IR, Coppolino M, Dedhar S, Dennis JW. Reduced contact-inhibition and substratum adhesion in epithelial cells expressing GlcNAc-transferase V. The Journal of Cell Biology. 130: 383-92. PMID 7615638 DOI: 10.1083/Jcb.130.2.383  0.388
1991 Korczak B, Kerbel RS, Dennis J. Constitutive expression and secretion of proteases in non-metastatic SP1 mammary carcinoma cells and its metastatic sublines. International Journal of Cancer. 48: 557-61. PMID 2045200 DOI: 10.1002/Ijc.2910480413  0.336
1990 Cornil I, Kerbel RS, Dennis JW. Tumor cell surface beta 1-4-linked galactose binds to lectin(s) on microvascular endothelial cells and contributes to organ colonization. The Journal of Cell Biology. 111: 773-81. PMID 2116422 DOI: 10.1083/jcb.111.2.773  0.33
1990 Yagel S, Kerbel R, Lala P, Eldar-Gera T, Dennis JW. Basement membrane invasion by first trimester human trophoblast: requirement for branched complex-type Asn-linked oligosaccharides. Clinical & Experimental Metastasis. 8: 305-17. PMID 2112436 DOI: 10.1007/Bf01810677  0.345
1989 Dennis JW, Laferté S, Vanderelst I. Asparagine-linked oligosaccharides in malignant tumour growth. Biochemical Society Transactions. 17: 29-31. PMID 2714513 DOI: 10.1042/bst0170029  0.356
1989 Yagel S, Feinmesser R, Waghorne C, Lala PK, Breitman ML, Dennis JW. Evidence that beta 1-6 branched Asn-linked oligosaccharides on metastatic tumor cells facilitate invasion of basement membranes. International Journal of Cancer. 44: 685-90. PMID 2507455 DOI: 10.1002/Ijc.2910440422  0.366
1987 Dennis JW, Laferté S, Waghorne C, Breitman ML, Kerbel RS. Beta 1-6 branching of Asn-linked oligosaccharides is directly associated with metastasis. Science (New York, N.Y.). 236: 582-5. PMID 2953071 DOI: 10.1126/Science.2953071  0.384
1982 Dennis J, Waller C, Timpl R, Schirrmacher V. Surface sialic acid reduces attachment of metastatic tumour cells to collagen type IV and fibronectin Nature. 300: 274-276. PMID 7144883 DOI: 10.1038/300274A0  0.339
1981 Dennis J, Donaghue T, Florian M, Kerbel RS. Apparent reversion of stable in vitro genetic markers detected in tumour cells from spontaneous metastases Nature. 292: 242-245. PMID 6894784 DOI: 10.1038/292242A0  0.32
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