Hugues Abriel - Publications

Affiliations: 
University of Bern, Bern, Bern, Switzerland 
Area:
ion channels, channelopathies

167/171 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Arullampalam P, Essers MC, Boukenna M, Guichard S, Rougier JS, Abriel H. Knockdown of the TRPM4 channel alters cardiac electrophysiology and hemodynamics in a sex- and age-dependent manner in mice. Physiological Reports. 11: e15783. PMID 37604672 DOI: 10.14814/phy2.15783  0.715
2023 Selimi Z, Rougier JS, Abriel H, Kucera JP. A detailed analysis of single-channel Na 1.5 recordings does not reveal any cooperative gating. The Journal of Physiology. 601: 3847-3868. PMID 37470338 DOI: 10.1113/JP284861  0.766
2023 Boukenna M, Rougier JS, Aghagolzadeh P, Pradervand S, Guichard S, Hämmerli AF, Pedrazzini T, Abriel H. Multiomics uncover the proinflammatory role of deletion after myocardial infarction in mice. American Journal of Physiology. Heart and Circulatory Physiology. 324: H504-H518. PMID 36800508 DOI: 10.1152/ajpheart.00671.2022  0.677
2022 Preti B, Rougier JS, Papapostolou I, Bochen F, Gerber CE, Abriel H, Lochner M, Peinelt C. Targeting Ion Channel TRPM4. Chimia. 76: 1039-1044. PMID 38069800 DOI: 10.2533/chimia.2022.1039  0.729
2022 Dokshokova L, Franzoso M, Di Bona A, Moro N, Sanchez Alonso JL, Prando V, Sandre M, Basso C, Faggian G, Abriel H, Marin O, Gorelik J, Zaglia T, Mongillo M. Nerve growth factor transfer from cardiomyocytes to innervating sympathetic neurons activates TrkA receptors at the neuro-cardiac junction. The Journal of Physiology. PMID 35413134 DOI: 10.1113/JP282828  0.345
2021 Arullampalam P, Preti B, Ross-Kaschitza D, Lochner M, Rougier JS, Abriel H. Species-Specific Effects of Cation Channel TRPM4 Small-Molecule Inhibitors. Frontiers in Pharmacology. 12: 712354. PMID 34335274 DOI: 10.3389/fphar.2021.712354  0.753
2021 Ozhathil LC, Rougier JS, Arullampalam P, Essers MC, Ross-Kaschitza D, Abriel H. Deletion of Alters the Function of the Na1.5 Channel in Murine Cardiac Myocytes. International Journal of Molecular Sciences. 22. PMID 33810249 DOI: 10.3390/ijms22073401  0.791
2021 Hu Y, Kaschitza DR, Essers M, Arullampalam P, Fujita T, Abriel H, Inoue R. Pathological activation of CaMKII induces arrhythmogenicity through TRPM4 overactivation. Pflugers Archiv : European Journal of Physiology. PMID 33392831 DOI: 10.1007/s00424-020-02507-w  0.508
2020 Wang Z, Vermij SH, Sottas V, Shestak A, Ross-Kaschitza D, Zaklyazminskaya EV, Hudmon A, Pitt GS, Rougier JS, Abriel H. Calmodulin binds to the N-terminal domain of the cardiac sodium channel Na1.5. Channels (Austin, Tex.). 14: 268-286. PMID 32815768 DOI: 10.1080/19336950.2020.1805999  0.846
2020 Vermij SH, Rougier JS, Agulló-Pascual E, Rothenberg E, Delmar M, Abriel H. Single-molecule Localization of Na1.5 Reveals Different Modes of Reorganization at Cardiomyocyte Membrane Domains. Circulation. Arrhythmia and Electrophysiology. PMID 32536203 DOI: 10.1161/Circep.119.008241  0.825
2020 Amarouch MY, Kurt H, Delemotte L, Abriel H. Biophysical Characterization of Epigallocatechin-3-Gallate Effect on the Cardiac Sodium Channel Na1.5. Molecules (Basel, Switzerland). 25. PMID 32085432 DOI: 10.3390/Molecules25040902  0.803
2019 Vermij SH, Abriel H, Kucera JP. Modeling Depolarization Delay, Sodium Currents, and Electrical Potentials in Cardiac Transverse Tubules. Frontiers in Physiology. 10: 1487. PMID 31920695 DOI: 10.3389/Fphys.2019.01487  0.808
2019 Gillet L, Guichard S, Essers MC, Rougier JS, Abriel H. Dystrophin and calcium current are decreased in cardiomyocytes expressing Cre enzyme driven by αMHC but not TNT promoter. Scientific Reports. 9: 19422. PMID 31857666 DOI: 10.1038/S41598-019-55950-W  0.824
2019 Casini S, Albesa M, Wang Z, Portero V, Ross-Kaschitza D, Rougier JS, Marchal GA, Chung WK, Bezzina CR, Abriel H, Remme CA. Functional Consequences of the -p.Y1977N Mutation within the PY Ubiquitylation Motif: Discrepancy between HEK293 Cells and Transgenic Mice. International Journal of Molecular Sciences. 20. PMID 31614475 DOI: 10.3390/Ijms20205033  0.835
2019 Neubauer J, Wang Z, Rougier JS, Abriel H, Rieubland C, Bartholdi D, Haas C, Medeiros-Domingo A. Functional characterization of a novel SCN5A variant associated with long QT syndrome and sudden cardiac death. International Journal of Legal Medicine. PMID 31455979 DOI: 10.1007/S00414-019-02141-X  0.845
2019 Rougier JS, Essers MC, Gillet L, Guichard S, Sonntag S, Shmerling D, Abriel H. A Distinct Pool of Na1.5 Channels at the Lateral Membrane of Murine Ventricular Cardiomyocytes. Frontiers in Physiology. 10: 834. PMID 31333492 DOI: 10.3389/Fphys.2019.00834  0.847
2019 Vermij SH, Abriel H, Kucera JP. A fundamental evaluation of the electrical properties and function of cardiac transverse tubules. Biochimica Et Biophysica Acta. Molecular Cell Research. PMID 31269418 DOI: 10.1016/J.Bbamcr.2019.06.016  0.801
2019 Marionneau C, Abriel H. Cardiac Sodium Current Under Sympathetic Control. Circulation Research. 124: 674-676. PMID 30817259 DOI: 10.1161/Circresaha.119.314680  0.488
2019 Delalande C, Awale M, Rubin M, Probst D, Ozhathil LC, Gertsch J, Abriel H, Reymond JL. Optimizing TRPM4 inhibitors in the MHFP6 chemical space. European Journal of Medicinal Chemistry. 166: 167-177. PMID 30708257 DOI: 10.1016/J.Ejmech.2019.01.048  0.394
2018 van der Heyden MAG, Delisle BP, Abriel H. Editorial: Ion Channel Trafficking and Cardiac Arrhythmias. Frontiers in Physiology. 9: 1254. PMID 30319434 DOI: 10.3389/Fphys.2018.01254  0.582
2018 Chevalier M, Vermij SH, Wyler K, Gillet L, Keller I, Abriel H. Corrigendum: Transcriptomic analyses of murine ventricular cardiomyocytes. Scientific Data. 5: 180216. PMID 30299437 DOI: 10.1038/Sdata.2018.216  0.773
2018 Tamo L, Hibaoui Y, Kallol S, Alves MP, Albrecht C, Hostettler KE, Feki A, Rougier JS, Abriel H, Knudsen L, Gazdhar A, Geiser T. Generation of an alveolar epithelial type II cell line from induced pluripotent stem cells. American Journal of Physiology. Lung Cellular and Molecular Physiology. PMID 30211653 DOI: 10.1152/Ajplung.00357.2017  0.675
2018 Chevalier M, Vermij SH, Wyler K, Gillet L, Keller I, Abriel H. Transcriptomic analyses of murine ventricular cardiomyocytes. Scientific Data. 5: 180170. PMID 30129933 DOI: 10.1038/Sdata.2018.170  0.838
2018 Bianchi B, Smith PA, Abriel H. The ion channel TRPM4 in murine experimental autoimmune encephalomyelitis and in a model of glutamate-induced neuronal degeneration. Molecular Brain. 11: 41. PMID 29996905 DOI: 10.1186/S13041-018-0385-4  0.745
2018 Neubauer J, Rougier JS, Abriel H, Haas C. Functional implications of a rare variant in the sodium channel β1B subunit () in a 5-month-old male sudden infant death syndrome case. Heartrhythm Case Reports. 4: 187-190. PMID 29915715 DOI: 10.1016/J.Hrcr.2018.01.010  0.707
2018 Ozhathil LC, Delalande C, Bianchi B, Nemeth G, Kappel S, Thomet U, Ross-Kaschitza D, Simonin C, Rubin M, Gertsch J, Lochner M, Peinelt C, Reymond JL, Abriel H. Identification of potent and selective small molecule inhibitors of the cation channel TRPM4. British Journal of Pharmacology. PMID 29579323 DOI: 10.1111/Bph.14220  0.731
2018 Bianchi B, Ozhathil LC, Medeiros-Domingo A, Gollob MH, Abriel H. Four TRPM4 Cation Channel Mutations Found in Cardiac Conduction Diseases Lead to Altered Protein Stability. Frontiers in Physiology. 9: 177. PMID 29568272 DOI: 10.3389/Fphys.2018.00177  0.8
2018 Casini S, Portero V, Rougier JS, Albesa M, Marchal GA, Chung WK, Bezzina CR, Abriel H, Remme CA. P265Functional characterization of a LQT3 mutation located in the PY motif of the cardiac sodium channel associated with altered channel ubiquitylation Cardiovascular Research. 114: S68-S68. DOI: 10.1093/Cvr/Cvy060.185  0.859
2017 Hichri E, Abriel H, Kucera JP. Distribution of cardiac sodium channels in clusters potentiates ephaptic interactions in the intercalated disc. The Journal of Physiology. PMID 29210458 DOI: 10.1113/Jp275351  0.565
2017 Hinard V, Britan A, Schaeffer M, Zahn-Zabal M, Thomet U, Rougier JS, Bairoch A, Abriel H, Gaudet P. Annotation of functional impact of voltage-gated sodium channel mutations. Human Mutation. PMID 28168870 DOI: 10.1002/Humu.23191  0.799
2017 Vermij SH, Abriel H, van Veen TA. Refining the molecular organization of the cardiac intercalated disc. Cardiovascular Research. PMID 28069669 DOI: 10.1093/Cvr/Cvw259  0.833
2017 Hichri E, Abriel H, Kucera JP. Ephaptic Effects Potentiate the Threshold Behavior of the Cardiac Sodium Current in a High Resolution Mathematical Model of a Narrow Intercellular Cleft Biophysical Journal. 112: 241a-242a. DOI: 10.1016/J.Bpj.2016.11.1322  0.615
2016 Eichel CA, Beuriot A, Chevalier MY, Rougier JS, Louault F, Dilanian G, Amour J, Coulombe A, Abriel H, Hatem SN, Balse E. Lateral Membrane-Specific MAGUK CASK Down-Regulates NaV1.5 Channel in Cardiac Myocytes. Circulation Research. 119: 544-56. PMID 27364017 DOI: 10.1161/Circresaha.116.309254  0.848
2016 Syam N, Chatel S, Ozhathil LC, Sottas V, Rougier JS, Baruteau A, Baron E, Amarouch MY, Daumy X, Probst V, Schott JJ, Abriel H. Variants of Transient Receptor Potential Melastatin Member 4 in Childhood Atrioventricular Block. Journal of the American Heart Association. 5. PMID 27207958 DOI: 10.1161/Jaha.114.001625  0.823
2016 Schaub MC, Abriel H. 8th Ascona International Workshop on Cardiomyocyte Biology, 3-7 May, 2015 Integration of Developmental and Environmental Cues in the Heart Congressi Stefano Franscini, Monte Verità, Ascona, Switzerland. Biochimica Et Biophysica Acta. 1863: 1691-5. PMID 27091768 DOI: 10.1016/J.Bbamcr.2016.04.008  0.387
2016 Hinard V, Britan A, Rougier JS, Bairoch A, Abriel H, Gaudet P. ICEPO: the ion channel electrophysiology ontology. Database : the Journal of Biological Databases and Curation. 2016. PMID 27055825 DOI: 10.1093/Database/Baw017  0.749
2016 Mohler PJ, Abriel H. Complexity of Cardiac Ion Channel Macromolecular Complexes. Cardiovascular Research. PMID 26984855 DOI: 10.1093/Cvr/Cvw055  0.626
2016 Amarouch MY, Swan H, Leinonen J, Marjamaa A, Lahtinen AM, Kontula K, Toivonen L, Widen E, Abriel H. Antiarrhythmic Action of Flecainide in Polymorphic Ventricular Arrhythmias Caused by a Gain-of-Function Mutation in the Nav 1.5 Sodium Channel. Annals of Noninvasive Electrocardiology : the Official Journal of the International Society For Holter and Noninvasive Electrocardiology, Inc. 21: 343-51. PMID 26965448 DOI: 10.1111/Anec.12312  0.818
2016 Sottas V, Abriel H. Negative-dominance phenomenon with genetic variants of the cardiac sodium channel Nav1.5. Biochimica Et Biophysica Acta. 1863: 1791-8. PMID 26907222 DOI: 10.1016/J.Bbamcr.2016.02.013  0.85
2016 Daumy X, Amarouch MY, Lindenbaum P, Bonnaud S, Charpentier E, Bianchi B, Nafzger S, Baron E, Fouchard S, Thollet A, Kyndt F, Barc J, Le Scouarnec S, Makita N, Le Marec H, ... ... Abriel H, et al. Targeted resequencing identifies TRPM4 as a major gene predisposing to progressive familial heart block type I. International Journal of Cardiology. 207: 349-58. PMID 26820365 DOI: 10.1016/J.Ijcard.2016.01.052  0.82
2016 Rougier JS, Abriel H. Cardiac voltage-gated calcium channel macromolecular complexes. Biochimica Et Biophysica Acta. 1863: 1806-12. PMID 26707467 DOI: 10.1016/J.Bbamcr.2015.12.014  0.804
2016 Daumy X, Amarouch MY, Lindenbaum P, Bonnaud S, Charpentier E, Bianchi B, Nafzger S, Baron E, Fouchard S, Thollet A, Kyndt F, Barc J, Le Scouarnec S, Makita N, Le Marec H, ... ... Abriel H, et al. Targeted resequencing identifies TRPM4 as a major gene predisposing to progressive familial heart block type i International Journal of Cardiology. 207: 349-358. DOI: 10.1016/j.ijcard.2016.01.052  0.788
2015 Laedermann CJ, Abriel H, Decosterd I. Post-translational modifications of voltage-gated sodium channels in chronic pain syndromes. Frontiers in Pharmacology. 6: 263. PMID 26594175 DOI: 10.3389/Fphar.2015.00263  0.805
2015 Abriel H, Rougier JS, Jalife J. Ion channel macromolecular complexes in cardiomyocytes: roles in sudden cardiac death. Circulation Research. 116: 1971-88. PMID 26044251 DOI: 10.1161/Circresaha.116.305017  0.788
2015 Abriel H. Genetic background of Brugada syndrome is more complex than what we would like it to be! Cardiovascular Research. 106: 351-2. PMID 25926434 DOI: 10.1093/Cvr/Cvv135  0.441
2015 Chen-Izu Y, Shaw RM, Pitt GS, Yarov-Yarovoy V, Sack JT, Abriel H, Aldrich RW, Belardinelli L, Cannell MB, Catterall WA, Chazin WJ, Chiamvimonvat N, Deschenes I, Grandi E, Hund TJ, et al. Na+ channel function, regulation, structure, trafficking and sequestration. The Journal of Physiology. 593: 1347-60. PMID 25772290 DOI: 10.1113/Jphysiol.2014.281428  0.594
2015 Marionneau C, Abriel H. Regulation of the cardiac Na+ channel NaV1.5 by post-translational modifications. Journal of Molecular and Cellular Cardiology. 82: 36-47. PMID 25748040 DOI: 10.1016/J.Yjmcc.2015.02.013  0.594
2015 Amarouch MY, Abriel H. Cellular hyper-excitability caused by mutations that alter the activation process of voltage-gated sodium channels. Frontiers in Physiology. 6: 45. PMID 25741286 DOI: 10.3389/Fphys.2015.00045  0.821
2015 Ossola D, Amarouch MY, Behr P, Vörös J, Abriel H, Zambelli T. Force-controlled patch clamp of beating cardiac cells. Nano Letters. 15: 1743-50. PMID 25639960 DOI: 10.1021/Nl504438Z  0.786
2015 Saber S, Amarouch MY, Fazelifar AF, Haghjoo M, Emkanjoo Z, Alizadeh A, Houshmand M, Gavrilenko AV, Abriel H, Zaklyazminskaya EV. Complex genetic background in a large family with Brugada syndrome. Physiological Reports. 3. PMID 25626866 DOI: 10.14814/Phy2.12256  0.789
2015 Gillet L, Rougier JS, Shy D, Sonntag S, Mougenot N, Essers M, Shmerling D, Balse E, Hatem SN, Abriel H. Cardiac-specific ablation of synapse-associated protein SAP97 in mice decreases potassium currents but not sodium current. Heart Rhythm : the Official Journal of the Heart Rhythm Society. 12: 181-92. PMID 25447080 DOI: 10.1016/J.Hrthm.2014.09.057  0.842
2015 Baruteau AE, Probst V, Abriel H. Inherited progressive cardiac conduction disorders. Current Opinion in Cardiology. 30: 33-9. PMID 25426816 DOI: 10.1097/Hco.0000000000000134  0.459
2015 Rougier JS, Albesa M, Syam N, Halet G, Abriel H, Viard P. Ubiquitin-specific protease USP2-45 acts as a molecular switch to promote α2δ-1-induced downregulation of Cav1.2 channels. Pflugers Archiv : European Journal of Physiology. 467: 1919-29. PMID 25366495 DOI: 10.1007/S00424-014-1636-6  0.842
2015 Suter MR, Bhuiyan ZA, Laedermann CJ, Kuntzer T, Schaller M, Stauffacher MW, Roulet E, Abriel H, Decosterd I, Wider C. p.L1612P, a novel voltage-gated sodium channel Nav1.7 mutation inducing a cold sensitive paroxysmal extreme pain disorder. Anesthesiology. 122: 414-23. PMID 25285947 DOI: 10.1097/Aln.0000000000000476  0.801
2015 Amarouch MY, Swan H, Leinonen J, Marjamaa A, Lahtinen AM, Kontula K, Toivonen L, Widen E, Abriel H. Antiarrhythmic Action of Flecainide in Polymorphic Ventricular Arrhythmias Caused by a Gain-of-Function Mutation in the Nav1.5 Sodium Channel Annals of Noninvasive Electrocardiology. DOI: 10.1016/S1878-6480(16)30436-0  0.809
2015 Rougier J, Abriel H. 0151 : Role a calcium/calmodulin-dependent serine protein kinase on Cav1.2 channel regulation Archives of Cardiovascular Diseases Supplements. 7: 167-168. DOI: 10.1016/S1878-6480(15)30101-4  0.788
2014 Amarouch MY, Kasimova MA, Tarek M, Abriel H. Functional interaction between S1 and S4 segments in voltage-gated sodium channels revealed by human channelopathies. Channels (Austin, Tex.). 8: 414-20. PMID 25483584 DOI: 10.4161/19336950.2014.958922  0.783
2014 Chevalier M, Amuzescu B, Gawali V, Todt H, Knott T, Scheel O, Abriel H. Late cardiac sodium current can be assessed using automated patch-clamp. F1000research. 3: 245. PMID 25383189 DOI: 10.12688/F1000Research.5544.1  0.708
2014 Shy D, Gillet L, Abriel H. Targeting the sodium channel NaV1.5 to specific membrane compartments of cardiac cells: not a simple task! Circulation Research. 115: 901-3. PMID 25378529 DOI: 10.1161/Circresaha.114.305305  0.85
2014 Gillet L, Shy D, Abriel H. Elucidating sodium channel NaV1.5 clustering in cardiac myocytes using super-resolution techniques. Cardiovascular Research. 104: 231-3. PMID 25341893 DOI: 10.1093/Cvr/Cvu221  0.863
2014 Swan H, Amarouch MY, Leinonen J, Marjamaa A, Kucera JP, Laitinen-Forsblom PJ, Lahtinen AM, Palotie A, Kontula K, Toivonen L, Abriel H, Widen E. Gain-of-function mutation of the SCN5A gene causes exercise-induced polymorphic ventricular arrhythmias. Circulation. Cardiovascular Genetics. 7: 771-81. PMID 25210054 DOI: 10.1161/Circgenetics.114.000703  0.805
2014 Shy D, Gillet L, Ogrodnik J, Albesa M, Verkerk AO, Wolswinkel R, Rougier JS, Barc J, Essers MC, Syam N, Marsman RF, van Mil AM, Rotman S, Redon R, Bezzina CR, ... ... Abriel H, et al. PDZ domain-binding motif regulates cardiomyocyte compartment-specific NaV1.5 channel expression and function. Circulation. 130: 147-60. PMID 24895455 DOI: 10.1161/Circulationaha.113.007852  0.834
2014 Laedermann CJ, Decosterd I, Abriel H. Ubiquitylation of voltage-gated sodium channels. Handbook of Experimental Pharmacology. 221: 231-50. PMID 24737239 DOI: 10.1007/978-3-642-41588-3_11  0.855
2014 Abriel H, Sottas V. Unexpected α-α interactions with NaV1.5 genetic variants in Brugada syndrome. Circulation. Cardiovascular Genetics. 7: 97-9. PMID 24736849 DOI: 10.1161/Circgenetics.114.000590  0.845
2014 Syam N, Rougier JS, Abriel H. Glycosylation of TRPM4 and TRPM5 channels: molecular determinants and functional aspects. Frontiers in Cellular Neuroscience. 8: 52. PMID 24605085 DOI: 10.3389/Fncel.2014.00052  0.855
2014 Clémençon B, Fine M, Lüscher B, Baumann MU, Surbek DV, Abriel H, Hediger MA. Expression, purification, and projection structure by single particle electron microscopy of functional human TRPM4 heterologously expressed in Xenopus laevis oocytes. Protein Expression and Purification. 95: 169-76. PMID 24333049 DOI: 10.1016/J.Pep.2013.11.017  0.491
2014 Hersch M, Peter B, Kang HM, Schüpfer F, Abriel H, Pedrazzini T, Eskin E, Beckmann JS, Bergmann S, Maurer F. Correction: Mapping genetic variants associated with beta-adrenergic responses in inbred mice (PLoS ONE) Plos One. 9. DOI: 10.1371/Annotation/16D5801B-2701-4Ec9-9D8E-278791A8A26A  0.333
2014 Amarouch MY, Leinonen J, Marjamaa A, Kucera JP, Laitinen-Forsblom PJ, Lahtinen AM, Palotie A, Kontula K, Toivonen L, Abriel H, Widen E, Swan H. 0265: A novel SCN5A mutation associated with exercise-induced polymorphic ventricular arrhythmias resembling CPVT Archives of Cardiovascular Diseases Supplements. 6: 41-42. DOI: 10.1016/S1878-6480(14)71376-X  0.8
2014 Gillet L, Shy D, Sonntag S, Rougier J, Verkerk A, Essers M, Marsman R, Shmerling D, Bezzina C, Remme CA, Abriel H. 0150: PDZ domain proteins interacting with Nav1.5 differentially regulate Nav1.5 channel pools in mouse cardiomyocytes Archives of Cardiovascular Diseases Supplements. 6: 40-41. DOI: 10.1016/S1878-6480(14)71373-4  0.857
2014 Abriel H. Cardiac Sodium Channel Disorders: One Gene with Many Genetic Variants Leading to Many Cardiac Phenotypes Cardiac Electrophysiology Clinics. 6: xv-xvi. DOI: 10.1016/J.Ccep.2014.08.009  0.569
2014 Abriel H. Cardiac Sodium Channel Nav1.5 and Drug-Induced Long QT Syndrome Cardiac Electrophysiology Clinics. 6: 777-783. DOI: 10.1016/J.Ccep.2014.08.006  0.566
2014 Syam N, Chatel S, Rougier J, Sottas V, Baruteau A, Probst V, Schott J, Abriel H. TRPM4 Genetic Variants in Patients with Congenital Atrio-Ventricular Block Biophysical Journal. 106: 762a. DOI: 10.1016/J.Bpj.2013.11.4192  0.812
2013 Reinhard K, Rougier JS, Ogrodnik J, Abriel H. Electrophysiological properties of mouse and epitope-tagged human cardiac sodium channel Na v1.5 expressed in HEK293 cells. F1000research. 2: 48. PMID 24555036 DOI: 10.12688/F1000Research.2-48.V2  0.825
2013 Abriel H, de Lange E, Kucera JP, Loussouarn G, Tarek M. Computational tools to investigate genetic cardiac channelopathies. Frontiers in Physiology. 4: 390. PMID 24421770 DOI: 10.3389/Fphys.2013.00390  0.471
2013 Andersen MN, Krzystanek K, Petersen F, Bomholtz SH, Olesen SP, Abriel H, Jespersen T, Rasmussen HB. A phosphoinositide 3-kinase (PI3K)-serum- and glucocorticoid-inducible kinase 1 (SGK1) pathway promotes Kv7.1 channel surface expression by inhibiting Nedd4-2 protein. The Journal of Biological Chemistry. 288: 36841-54. PMID 24214981 DOI: 10.1074/Jbc.M113.525931  0.459
2013 Laedermann CJ, Syam N, Pertin M, Decosterd I, Abriel H. β1- and β3- voltage-gated sodium channel subunits modulate cell surface expression and glycosylation of Nav1.7 in HEK293 cells. Frontiers in Cellular Neuroscience. 7: 137. PMID 24009557 DOI: 10.3389/Fncel.2013.00137  0.791
2013 Abriel H, Rougier JS. β-blockers in congenital short-QT syndrome as ion channel blockers. Journal of Cardiovascular Electrophysiology. 24: 1172-4. PMID 23890274 DOI: 10.1111/Jce.12204  0.744
2013 Gillet L, Shy D, Abriel H. NaV1.5 and interacting proteins in human arrhythmogenic cardiomyopathy. Future Cardiology. 9: 467-70. PMID 23834686 DOI: 10.2217/Fca.13.38  0.848
2013 Laedermann CJ, Cachemaille M, Kirschmann G, Pertin M, Gosselin RD, Chang I, Albesa M, Towne C, Schneider BL, Kellenberger S, Abriel H, Decosterd I. Dysregulation of voltage-gated sodium channels by ubiquitin ligase NEDD4-2 in neuropathic pain. The Journal of Clinical Investigation. 123: 3002-13. PMID 23778145 DOI: 10.1172/Jci68996  0.813
2013 Pérez López I, Cariolato L, Maric D, Gillet L, Abriel H, Diviani D. A-kinase anchoring protein Lbc coordinates a p38 activating signaling complex controlling compensatory cardiac hypertrophy. Molecular and Cellular Biology. 33: 2903-17. PMID 23716597 DOI: 10.1128/Mcb.00031-13  0.705
2013 Sottas V, Rougier JS, Jousset F, Kucera JP, Shestak A, Makarov LM, Zaklyazminskaya EV, Abriel H. Characterization of 2 genetic variants of Na(v) 1.5-arginine 689 found in patients with cardiac arrhythmias. Journal of Cardiovascular Electrophysiology. 24: 1037-46. PMID 23692053 DOI: 10.1111/Jce.12173  0.847
2013 Pouly D, Debonneville A, Ruffieux-Daidié D, Maillard M, Abriel H, Loffing J, Staub O. Mice carrying ubiquitin-specific protease 2 (Usp2) gene inactivation maintain normal sodium balance and blood pressure. American Journal of Physiology. Renal Physiology. 305: F21-30. PMID 23552861 DOI: 10.1152/Ajprenal.00012.2013  0.468
2013 Rougier JS, Gavillet B, Abriel H. Proteasome inhibitor (MG132) rescues Nav1.5 protein content and the cardiac sodium current in dystrophin-deficient mdx (5cv) mice. Frontiers in Physiology. 4: 51. PMID 23532763 DOI: 10.3389/Fphys.2013.00051  0.837
2013 Amarouch MY, Syam N, Abriel H. Biochemical, single-channel, whole-cell patch clamp, and pharmacological analyses of endogenous TRPM4 channels in HEK293 cells. Neuroscience Letters. 541: 105-10. PMID 23428507 DOI: 10.1016/J.Neulet.2013.02.011  0.835
2013 Liu H, Chatel S, Simard C, Syam N, Salle L, Probst V, Morel J, Millat G, Lopez M, Abriel H, Schott JJ, Guinamard R, Bouvagnet P. Molecular genetics and functional anomalies in a series of 248 Brugada cases with 11 mutations in the TRPM4 channel. Plos One. 8: e54131. PMID 23382873 DOI: 10.1371/Journal.Pone.0054131  0.843
2013 Abriel H, Zaklyazminskaya EV. Cardiac channelopathies: genetic and molecular mechanisms. Gene. 517: 1-11. PMID 23266818 DOI: 10.1016/J.Gene.2012.12.061  0.604
2013 Suter MR, Kirschmann G, Laedermann CJ, Abriel H, Decosterd I. Rufinamide attenuates mechanical allodynia in a model of neuropathic pain in the mouse and stabilizes voltage-gated sodium channel inactivated state. Anesthesiology. 118: 160-72. PMID 23221868 DOI: 10.1097/Aln.0B013E318278Cade  0.824
2013 Shy D, Gillet L, Abriel H. Cardiac sodium channel NaV1.5 distribution in myocytes via interacting proteins: the multiple pool model. Biochimica Et Biophysica Acta. 1833: 886-94. PMID 23123192 DOI: 10.1016/J.Bbamcr.2012.10.026  0.866
2013 Ossola D, Behr P, Amarouch M, Abriel H, Vörös J, Zambelli T. Fluidfm for Force Controlled Electrophysiology Biophysical Journal. 104: 502a. DOI: 10.1016/J.Bpj.2012.11.2771  0.72
2012 Abriel H, Zaklyazminskaya EV. A modern approach to classify missense mutations in cardiac channelopathy genes. Circulation. Cardiovascular Genetics. 5: 487-9. PMID 23074335 DOI: 10.1161/Circgenetics.112.964809  0.633
2012 Cachemaille M, Laedermann CJ, Pertin M, Abriel H, Gosselin RD, Decosterd I. Neuronal expression of the ubiquitin ligase Nedd4-2 in rat dorsal root ganglia: modulation in the spared nerve injury model of neuropathic pain. Neuroscience. 227: 370-80. PMID 23022218 DOI: 10.1016/J.Neuroscience.2012.09.044  0.798
2012 Rougier JS, Abriel H. Role of "non-cardiac" voltage-gated sodium channels in cardiac cells. Journal of Molecular and Cellular Cardiology. 53: 589-90. PMID 22967322 DOI: 10.1016/J.Yjmcc.2012.08.011  0.796
2012 Rougier JS, Abriel H. Unexpected dominance: Brugada syndrome SCN5A variants exert negative dominance via α-subunit interaction. Cardiovascular Research. 96: 1-3. PMID 22871588 DOI: 10.1093/Cvr/Cvs264  0.779
2012 Hersch M, Peter B, Kang HM, Schüpfer F, Abriel H, Pedrazzini T, Eskin E, Beckmann JS, Bergmann S, Maurer F. Mapping genetic variants associated with beta-adrenergic responses in inbred mice. Plos One. 7: e41032. PMID 22859963 DOI: 10.1371/Journal.Pone.0041032  0.394
2012 Balse E, Steele DF, Abriel H, Coulombe A, Fedida D, Hatem SN. Dynamic of ion channel expression at the plasma membrane of cardiomyocytes. Physiological Reviews. 92: 1317-58. PMID 22811429 DOI: 10.1152/Physrev.00041.2011  0.612
2012 Abriel H, Syam N, Sottas V, Amarouch MY, Rougier JS. TRPM4 channels in the cardiovascular system: physiology, pathophysiology, and pharmacology. Biochemical Pharmacology. 84: 873-81. PMID 22750058 DOI: 10.1016/J.Bcp.2012.06.021  0.839
2012 Abriel H. Cardiac sodium channel Na(v)1.5 mechanosensitivity is inhibited by ranolazine. Circulation. 125: 2681-3. PMID 22565937 DOI: 10.1161/Circulationaha.112.110908  0.664
2012 Zaklyazminskaya EV, Abriel H. Prevalence of Significant Genetic Variants in Congenital Long QT Syndrome is Largely Underestimated. Frontiers in Pharmacology. 3: 72. PMID 22557970 DOI: 10.3389/Fphar.2012.00072  0.422
2012 Krzystanek K, Rasmussen HB, Grunnet M, Staub O, Olesen SP, Abriel H, Jespersen T. Deubiquitylating enzyme USP2 counteracts Nedd4-2-mediated downregulation of KCNQ1 potassium channels. Heart Rhythm : the Official Journal of the Heart Rhythm Society. 9: 440-8. PMID 22024150 DOI: 10.1016/J.Hrthm.2011.10.026  0.608
2011 Sintra Grilo L, Carrupt PA, Abriel H, Daina A. Block of the hERG channel by bupivacaine: Electrophysiological and modeling insights towards stereochemical optimization. European Journal of Medicinal Chemistry. 46: 3486-98. PMID 21624711 DOI: 10.1016/J.Ejmech.2011.05.015  0.595
2011 Grilo LS, Schläpfer J, Fellmann F, Abriel H. Patient with syncope and LQTS carrying a mutation in the PAS domain of the hERG1 channel. Annals of Noninvasive Electrocardiology : the Official Journal of the International Society For Holter and Noninvasive Electrocardiology, Inc. 16: 213-8. PMID 21496174 DOI: 10.1111/J.1542-474X.2011.00419.X  0.824
2011 Albesa M, Grilo LS, Gavillet B, Abriel H. Nedd4-2-dependent ubiquitylation and regulation of the cardiac potassium channel hERG1. Journal of Molecular and Cellular Cardiology. 51: 90-8. PMID 21463633 DOI: 10.1016/J.Yjmcc.2011.03.015  0.859
2011 Templin C, Ghadri JR, Rougier JS, Baumer A, Kaplan V, Albesa M, Sticht H, Rauch A, Puleo C, Hu D, Barajas-Martinez H, Antzelevitch C, Lüscher TF, Abriel H, Duru F. Identification of a novel loss-of-function calcium channel gene mutation in short QT syndrome (SQTS6). European Heart Journal. 32: 1077-88. PMID 21383000 DOI: 10.1093/Eurheartj/Ehr076  0.843
2011 Rougier JS, Albesa M, Abriel H, Viard P. Neuronal precursor cell-expressed developmentally down-regulated 4-1 (NEDD4-1) controls the sorting of newly synthesized Ca(V)1.2 calcium channels. The Journal of Biological Chemistry. 286: 8829-38. PMID 21220429 DOI: 10.1074/Jbc.M110.166520  0.825
2011 Petitprez S, Zmoos AF, Ogrodnik J, Balse E, Raad N, El-Haou S, Albesa M, Bittihn P, Luther S, Lehnart SE, Hatem SN, Coulombe A, Abriel H. SAP97 and dystrophin macromolecular complexes determine two pools of cardiac sodium channels Nav1.5 in cardiomyocytes. Circulation Research. 108: 294-304. PMID 21164104 DOI: 10.1161/Circresaha.110.228312  0.841
2011 Albesa M, Ogrodnik J, Rougier JS, Abriel H. Regulation of the cardiac sodium channel Nav1.5 by utrophin in dystrophin-deficient mice. Cardiovascular Research. 89: 320-8. PMID 20952415 DOI: 10.1016/J.Hrthm.2010.09.031  0.834
2011 Suter MR, Kirschmann G, Abriel H, Decosterd I. Rufinamide alleviates mechanical allodynia in a mouse neuropathic pain model European Journal of Anaesthesiology. 28: 193. DOI: 10.1097/00003643-201106001-00622  0.223
2011 Laedermann C, Cachemaille M, Abriel H, Decosterd I. The ubiquitin ligase Nedd4-2 is a potent regulator of the voltage-gated sodium channel Nav1.7 and is implicated in neuropathic pain European Journal of Anaesthesiology. 28: 2. DOI: 10.1097/00003643-201106001-00006  0.829
2010 Grilo LS, Carrupt PA, Abriel H. Stereoselective Inhibition of the hERG1 Potassium Channel. Frontiers in Pharmacology. 1: 137. PMID 21833176 DOI: 10.3389/Fphar.2010.00137  0.798
2010 Pignier C, Rougier JS, Vié B, Culié C, Verscheure Y, Vacher B, Abriel H, Le Grand B. Selective inhibition of persistent sodium current by F 15845 prevents ischaemia-induced arrhythmias. British Journal of Pharmacology. 161: 79-91. PMID 20718741 DOI: 10.1111/J.1476-5381.2010.00884.X  0.733
2010 Rougier JS, Albesa M, Abriel H. Ubiquitylation and SUMOylation of cardiac ion channels. Journal of Cardiovascular Pharmacology. 56: 22-8. PMID 20224423 DOI: 10.1097/Fjc.0B013E3181Daaff9  0.845
2010 Leoni AL, Gavillet B, Rougier JS, Marionneau C, Probst V, Le Scouarnec S, Schott JJ, Demolombe S, Bruneval P, Huang CL, Colledge WH, Grace AA, Le Marec H, Wilde AA, Mohler PJ, ... ... Abriel H, et al. Variable Na(v)1.5 protein expression from the wild-type allele correlates with the penetrance of cardiac conduction disease in the Scn5a(+/-) mouse model. Plos One. 5: e9298. PMID 20174578 DOI: 10.1371/Journal.Pone.0009298  0.827
2010 Grilo LS, Pruvot E, Grobéty M, Castella V, Fellmann F, Abriel H. Takotsubo cardiomyopathy and congenital long QT syndrome in a patient with a novel duplication in the Per-Arnt-Sim (PAS) domain of hERG1. Heart Rhythm : the Official Journal of the Heart Rhythm Society. 7: 260-5. PMID 20004623 DOI: 10.1016/J.Hrthm.2009.09.026  0.781
2010 Stirnimann G, Petitprez S, Abriel H, Schwick NG. Brugada syndrome ECG provoked by the selective serotonin reuptake inhibitor fluvoxamine. Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups On Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology. 12: 282-3. PMID 19875396 DOI: 10.1093/Europace/Eup332  0.853
2010 Abriel H. Cardiac sodium channel Na(v)1.5 and interacting proteins: Physiology and pathophysiology. Journal of Molecular and Cellular Cardiology. 48: 2-11. PMID 19744495 DOI: 10.1016/J.Yjmcc.2009.08.025  0.628
2010 Krzystanek K, Grunnet M, Olesen SP, Abriel H, Jespersen T. Regulation of the Cardiac Iks Channel Complex by Ubiquitylation and De-Ubiquitylation Biophysical Journal. 98: 534a. DOI: 10.1016/J.Bpj.2009.12.2897  0.644
2009 Michaud K, Fellmann F, Abriel H, Beckmann JS, Mangin P, Elger BS. Molecular autopsy in sudden cardiac death and its implication for families: discussion of the practical, legal and ethical aspects of the multidisciplinary collaboration. Swiss Medical Weekly. 139: 712-8. PMID 20047134 DOI: 10.4414/Smw.2009.12837  0.415
2009 Berthonneche C, Peter B, Schüpfer F, Hayoz P, Kutalik Z, Abriel H, Pedrazzini T, Beckmann JS, Bergmann S, Maurer F. Cardiovascular response to beta-adrenergic blockade or activation in 23 inbred mouse strains. Plos One. 4: e6610. PMID 19672458 DOI: 10.1371/Journal.Pone.0006610  0.366
2009 Kurokawa J, Abriel H. Neurohormonal regulation of cardiac ion channels in chronic heart failure. Journal of Cardiovascular Pharmacology. 54: 98-105. PMID 19597366 DOI: 10.1097/Fjc.0B013E3181B2B6D4  0.738
2009 Tfelt-Hansen J, Jespersen T, Hofman-Bang J, Rasmussen HB, Cedergreen P, Skovby F, Abriel H, Svendsen JH, Olesen SP, Christiansen M, Haunso S. Ventricular tachycardia in a Brugada syndrome patient caused by a novel deletion in SCN5A. The Canadian Journal of Cardiology. 25: 156-60. PMID 19279983 DOI: 10.1016/S0828-282X(09)70043-1  0.505
2009 El-Haou S, Balse E, Neyroud N, Dilanian G, Gavillet B, Abriel H, Coulombe A, Jeromin A, Hatem SN. Kv4 potassium channels form a tripartite complex with the anchoring protein SAP97 and CaMKII in cardiac myocytes. Circulation Research. 104: 758-69. PMID 19213956 DOI: 10.1161/Circresaha.108.191007  0.847
2009 Albesa M, Rougier J, Abriel H, Viard P. G010 Regulation of voltage-dependent calcium channels by Nedd4-1 Archives of Cardiovascular Diseases. 102: S65. DOI: 10.1016/S1875-2136(09)72285-5  0.857
2009 Petitprez S, Zmoos A, Hatem S, Coulombe A, Abriel H. G009 Regulation of the cardiac sodium channel Nav1.5 by a member of MAGUK proteins: SAP97 Archives of Cardiovascular Diseases. 102: S65. DOI: 10.1016/S1875-2136(09)72284-3  0.861
2009 Sintra Grilo L, Pruvot E, Grobety M, Castella V, Fellmann F, Abriel H, Abriel H. G003 Characterization of a novel 7-amino-acid duplication located in the pas domain of hERG found in a patient with congenital long QT syndrome Archives of Cardiovascular Diseases. 102: S62-S63. DOI: 10.1016/S1875-2136(09)72278-8  0.55
2009 El-Haou S, Balse E, Neyroud N, Gavillet B, Abriel H, Coulombe A, Jeromin A, Hatem SN. The Anchoring Protein SAP97 Is Crucial For The Surface Expression Of Shal Kv Potassium Channels And Their Regulation By CaMKII In Cardiac Myocytes Biophysical Journal. 96: 261a. DOI: 10.1016/J.Bpj.2008.12.1291  0.844
2008 Petitprez S, Tiab L, Chen L, Kappeler L, Rösler KM, Schorderet D, Abriel H, Burgunder JM. A novel dominant mutation of the Nav1.4 alpha-subunit domain I leading to sodium channel myotonia. Neurology. 71: 1669-75. PMID 19015483 DOI: 10.1212/01.Wnl.0000335168.86248.55  0.822
2008 Petitprez S, Abriel H. Crosstalk between cardiac ion channel subunits: an encrypted language to be deciphered. Journal of Molecular and Cellular Cardiology. 45: 333-5. PMID 18582471 DOI: 10.1016/J.Yjmcc.2008.05.019  0.832
2008 Grilo LS, Abriel H. Male and female equality: still far from goal. The Journal of Physiology. 586: 2825-6. PMID 18556724 DOI: 10.1113/Jphysiol.2008.156398  0.802
2008 Petitprez S, Jespersen T, Pruvot E, Keller DI, Corbaz C, Schläpfer J, Abriel H, Kucera JP. Analyses of a novel SCN5A mutation (C1850S): conduction vs. repolarization disorder hypotheses in the Brugada syndrome. Cardiovascular Research. 78: 494-504. PMID 18252757 DOI: 10.1093/Cvr/Cvn023  0.834
2008 Petitprez S, Abriel H. Effects of heart failure on brain-type Na+ channels in rabbit ventricular myocytes. Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups On Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology. 10: 257; author reply 25. PMID 18056137 DOI: 10.1093/Europace/Eum266  0.839
2008 Rougier JS, Muller O, Berger S, Centeno G, Schütz G, Firsov D, Abriel H. Mineralocorticoid receptor is essential for corticosteroid-induced up-regulation of L-type calcium currents in cultured neonatal cardiomyocytes. Pflã¼Gers Archiv : European Journal of Physiology. 456: 407-12. PMID 18040710 DOI: 10.1007/S00424-007-0387-Z  0.723
2008 Eap C, Crettol S, Rougier J, Schläpfer J, Sintra Grilo L, Déglon J, Besson J, Croquette-Krokar M, Carrupt P, Abriel H. Stereoselective Block of hERG Channel by (S)-Methadone and QT Interval Prolongation in CYP2B6 Slow Metabolizer: Evidence of a Safer Cardiac Profile of (R)-Methadone Pharmacopsychiatry. 41. DOI: 10.1055/S-0028-1088244  0.464
2008 Crettol S, Schlaepfer J, Abriel H, Eap C. Response to “Methadone-Induced QTc Prolongation: Is it Due to Stereoselective Block of hERG or to Inappropriate QT Interval Correction?” Clinical Pharmacology & Therapeutics. 83: 672-672. DOI: 10.1038/Sj.Clpt.6100426  0.365
2007 Kranjcec D, Bergovec M, Rougier JS, Raguz M, Pavlovic S, Jespersen T, Castella V, Keller DI, Abriel H. Brugada syndrome unmasked by accidental inhalation of gasoline vapors. Pacing and Clinical Electrophysiology : Pace. 30: 1294-8. PMID 17897138 DOI: 10.1111/J.1540-8159.2007.00857.X  0.724
2007 Abriel H. Roles and regulation of the cardiac sodium channel Na v 1.5: recent insights from experimental studies. Cardiovascular Research. 76: 381-9. PMID 17727828 DOI: 10.1016/J.Cardiores.2007.07.019  0.617
2007 Eap CB, Crettol S, Rougier JS, Schläpfer J, Sintra Grilo L, Déglon JJ, Besson J, Croquette-Krokar M, Carrupt PA, Abriel H. Stereoselective block of hERG channel by (S)-methadone and QT interval prolongation in CYP2B6 slow metabolizers. Clinical Pharmacology and Therapeutics. 81: 719-28. PMID 17329992 DOI: 10.1038/Sj.Clpt.6100120  0.462
2007 Jespersen T, Membrez M, Nicolas CS, Pitard B, Staub O, Olesen SP, Baró I, Abriel H. The KCNQ1 potassium channel is down-regulated by ubiquitylating enzymes of the Nedd4/Nedd4-like family. Cardiovascular Research. 74: 64-74. PMID 17289006 DOI: 10.1016/J.Cardiores.2007.01.008  0.617
2007 Domenighetti AA, Boixel C, Cefai D, Abriel H, Pedrazzini T. Chronic angiotensin II stimulation in the heart produces an acquired long QT syndrome associated with IK1 potassium current downregulation. Journal of Molecular and Cellular Cardiology. 42: 63-70. PMID 17070838 DOI: 10.1016/J.Yjmcc.2006.09.019  0.523
2006 Jespersen T, Gavillet B, van Bemmelen MX, Cordonier S, Thomas MA, Staub O, Abriel H. Cardiac sodium channel Na(v)1.5 interacts with and is regulated by the protein tyrosine phosphatase PTPH1. Biochemical and Biophysical Research Communications. 348: 1455-62. PMID 16930557 DOI: 10.1016/J.Bbrc.2006.08.014  0.829
2006 Gavillet B, Rougier JS, Domenighetti AA, Behar R, Boixel C, Ruchat P, Lehr HA, Pedrazzini T, Abriel H. Cardiac sodium channel Nav1.5 is regulated by a multiprotein complex composed of syntrophins and dystrophin Circulation Research. 99: 407-414. PMID 16857961 DOI: 10.1161/01.Res.0000237466.13252.5E  0.843
2006 Fodstad H, Bendahhou S, Rougier JS, Laitinen-Forsblom PJ, Barhanin J, Abriel H, Schild L, Kontula K, Swan H. Molecular characterization of two founder mutations causing long QT syndrome and identification of compound heterozygous patients. Annals of Medicine. 38: 294-304. PMID 16754261 DOI: 10.1080/07853890600756065  0.707
2006 Camacho JA, Hensellek S, Rougier JS, Blechschmidt S, Abriel H, Benndorf K, Zimmer T. Modulation of Nav1.5 channel function by an alternatively spliced sequence in the DII/DIII linker region. The Journal of Biological Chemistry. 281: 9498-506. PMID 16469732 DOI: 10.1074/Jbc.M509716200  0.783
2006 Boixel C, Gavillet B, Rougier JS, Abriel H. Aldosterone increases voltage-gated sodium current in ventricular myocytes. American Journal of Physiology. Heart and Circulatory Physiology. 290: H2257-66. PMID 16428353 DOI: 10.1152/Ajpheart.01060.2005  0.841
2005 Abriel H, Staub O. Ubiquitylation of ion channels. Physiology (Bethesda, Md.). 20: 398-407. PMID 16287989 DOI: 10.1152/Physiol.00033.2005  0.563
2005 Keller DI, Rougier JS, Kucera JP, Benammar N, Fressart V, Guicheney P, Madle A, Fromer M, Schläpfer J, Abriel H. Brugada syndrome and fever: genetic and molecular characterization of patients carrying SCN5A mutations. Cardiovascular Research. 67: 510-9. PMID 15890323 DOI: 10.1016/J.Cardiores.2005.03.024  0.765
2005 Abriel H, Kass RS. Regulation of the voltage-gated cardiac sodium channel Nav1.5 by interacting proteins. Trends in Cardiovascular Medicine. 15: 35-40. PMID 15795161 DOI: 10.1016/J.Tcm.2005.01.001  0.745
2005 Rougier JS, van Bemmelen MX, Bruce MC, Jespersen T, Gavillet B, Apothéloz F, Cordonier S, Staub O, Rotin D, Abriel H. Molecular determinants of voltage-gated sodium channel regulation by the Nedd4/Nedd4-like proteins. American Journal of Physiology. Cell Physiology. 288: C692-701. PMID 15548568 DOI: 10.1152/Ajpcell.00460.2004  0.831
2004 Abriel H, Schläpfer J, Keller DI, Gavillet B, Buclin T, Biollaz J, Stoller R, Kappenberger L. Molecular and clinical determinants of drug-induced long QT syndrome: an iatrogenic channelopathy. Swiss Medical Weekly. 134: 685-94. PMID 15616901 DOI: 10.4414/Smw.2004.10532  0.756
2004 Le Bouter S, El Harchi A, Marionneau C, Bellocq C, Chambellan A, van Veen T, Boixel C, Gavillet B, Abriel H, Le Quang K, Chevalier JC, Lande G, Léger JJ, Charpentier F, Escande D, et al. Long-term amiodarone administration remodels expression of ion channel transcripts in the mouse heart. Circulation. 110: 3028-35. PMID 15520326 DOI: 10.1161/01.Cir.0000147187.78162.Ac  0.815
2004 van Bemmelen MX, Rougier JS, Gavillet B, Apothéloz F, Daidié D, Tateyama M, Rivolta I, Thomas MA, Kass RS, Staub O, Abriel H. Cardiac voltage-gated sodium channel Nav1.5 is regulated by Nedd4-2 mediated ubiquitination. Circulation Research. 95: 284-91. PMID 15217910 DOI: 10.1161/01.Res.0000136816.05109.89  0.851
2004 Blot V, Perugi F, Gay B, Prévost MC, Briant L, Tangy F, Abriel H, Staub O, Dokhélar MC, Pique C. Nedd4.1-mediated ubiquitination and subsequent recruitment of Tsg101 ensure HTLV-1 Gag trafficking towards the multivesicular body pathway prior to virus budding. Journal of Cell Science. 117: 2357-67. PMID 15126635 DOI: 10.1242/Jcs.01095  0.413
2002 Liu H, Tateyama M, Clancy CE, Abriel H, Kass RS. Channel openings are necessary but not sufficient for use-dependent block of cardiac Na(+) channels by flecainide: evidence from the analysis of disease-linked mutations. The Journal of General Physiology. 120: 39-51. PMID 12084774 DOI: 10.1085/Jgp.20028558  0.741
2001 Rivolta I, Abriel H, Tateyama M, Liu H, Memmi M, Vardas P, Napolitano C, Priori SG, Kass RS. Inherited Brugada and long QT-3 syndrome mutations of a single residue of the cardiac sodium channel confer distinct channel and clinical phenotypes. The Journal of Biological Chemistry. 276: 30623-30. PMID 11410597 DOI: 10.1074/Jbc.M104471200  0.74
2001 Kurokawa J, Abriel H, Kass RS. Molecular basis of the delayed rectifier current I(ks)in heart. Journal of Molecular and Cellular Cardiology. 33: 873-82. PMID 11343411 DOI: 10.1006/Jmcc.2001.1377  0.795
2001 Abriel H, Cabo C, Wehrens XH, Rivolta I, Motoike HK, Memmi M, Napolitano C, Priori SG, Kass RS. Novel arrhythmogenic mechanism revealed by a long-QT syndrome mutation in the cardiac Na(+) channel. Circulation Research. 88: 740-5. PMID 11304498 DOI: 10.1161/Hh0701.089668  0.754
2001 Dhar Malhotra J, Chen C, Rivolta I, Abriel H, Malhotra R, Mattei LN, Brosius FC, Kass RS, Isom LL. Characterization of sodium channel alpha- and beta-subunits in rat and mouse cardiac myocytes. Circulation. 103: 1303-10. PMID 11238277 DOI: 10.1161/01.Cir.103.9.1303  0.637
2000 Abriel H, Wehrens XH, Benhorin J, Kerem B, Kass RS. Molecular pharmacology of the sodium channel mutation D1790G linked to the long-QT syndrome. Circulation. 102: 921-5. PMID 10952963 DOI: 10.1161/01.Cir.102.8.921  0.73
2000 Wehrens XH, Abriel H, Cabo C, Benhorin J, Kass RS. Arrhythmogenic mechanism of an LQT-3 mutation of the human heart Na(+) channel alpha-subunit: A computational analysis. Circulation. 102: 584-90. PMID 10920073 DOI: 10.1161/01.Cir.102.5.584  0.752
2000 Abriel H, Motoike H, Kass RS. KChAP: a novel chaperone for specific K(+) channels key to repolarization of the cardiac action potential. Focus on "KChAP as a chaperone for specific K(+) channels". American Journal of Physiology. Cell Physiology. 278: C863-4. PMID 10794658 DOI: 10.1152/Ajpcell.2000.278.5.C863  0.709
2000 Staub O, Abriel H, Plant P, Ishikawa T, Kanelis V, Saleki R, Horisberger JD, Schild L, Rotin D. Regulation of the epithelial Na+ channel by Nedd4 and ubiquitination. Kidney International. 57: 809-15. PMID 10720933 DOI: 10.1046/J.1523-1755.2000.00919.X  0.555
2000 Abriel H, Kamynina E, Horisberger JD, Staub O. Regulation of the cardiac voltage-gated Na+ channel (H1) by the ubiquitin-protein ligase Nedd4. Febs Letters. 466: 377-80. PMID 10682864 DOI: 10.1016/S0014-5793(00)01098-X  0.639
1999 Abriel H, Hasler U, Geering K, Horisberger JD. Role of the intracellular domain of the beta subunit in Na,K pump function. Biochimica Et Biophysica Acta. 1418: 85-96. PMID 10209213 DOI: 10.1016/S0005-2736(99)00025-5  0.415
1999 Abriel H, Loffing J, Rebhun JF, Pratt JH, Schild L, Horisberger JD, Rotin D, Staub O. Defective regulation of the epithelial Na+ channel by Nedd4 in Liddle's syndrome. The Journal of Clinical Investigation. 103: 667-73. PMID 10074483 DOI: 10.1172/Jci5713  0.568
1999 Abriel H, Horisberger JD. Feedback inhibition of rat amiloride-sensitive epithelial sodium channels expressed in Xenopus laevis oocytes. The Journal of Physiology. 31-43. PMID 10066920 DOI: 10.1111/J.1469-7793.1999.031Aa.X  0.51
1995 Abriel H, Katz U, Kucera P. Ion transport across the early chick embryo: II. Characterization and pH sensitivity of the transembryonic short-circuit current. The Journal of Membrane Biology. 141: 159-66. PMID 7807518 DOI: 10.1007/Bf00238249  0.481
1995 Kucera P, Abriel H, Katz U. Ion transport across the early chick embryo: I. Electrical measurements, ionic fluxes and regional heterogeneity. The Journal of Membrane Biology. 141: 149-57. PMID 7807517 DOI: 10.1007/Bf00238248  0.409
1992 Schlumpf M, Parmar R, Schreiber A, Ramseier H, Bütikofer E, Abriel H, Barth M, Rhymer T, Lichtensteiger W. Nervous and Immune Systems as Targets for Developmental Effects of Benzodiazepines Developmental Pharmacology and Therapeutics. 18: 145-158. DOI: 10.1159/000480614  0.365
Low-probability matches (unlikely to be authored by this person)
2022 Rossetti V, Abriel H. The NCCR TransCure: An Incubator for Interdisciplinary Research. Chimia. 76: 992-995. PMID 38069793 DOI: 10.2533/chimia.2022.992  0.128
2024 Iamshanova O, Hämmerli AF, Ramaye E, Seljmani A, Ross-Kaschitza D, Schärz N, Essers M, Guichard S, Rougier JS, Abriel H. The dispensability of 14-3-3 proteins for the regulation of human cardiac sodium channel Nav1.5. Plos One. 19: e0298820. PMID 38452156 DOI: 10.1371/journal.pone.0298820  0.12
2024 El Makhzen N, Daimi H, Bouguenouch L, Abriel H. The burden of cystic fibrosis in North Africa. Frontiers in Genetics. 14: 1295008. PMID 38269366 DOI: 10.3389/fgene.2023.1295008  0.12
2022 Abriel H, Reymond JL. NCCR TransCure - Excellence in Membrane Transport Research from 2010 until 2022. Chimia. 76: 989. PMID 38069792  0.081
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