Jean-Sébastien Rougier - Publications

Affiliations: 
2002-2006 Pharmacology and Toxicology University of Lausanne 

38 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Wang Z, Vermij SH, Sottas V, Shestak A, Ross-Kaschitza D, Zaklyazminskaya EV, Hudmon A, Pitt GS, Rougier JS, Abriel H. Calmodulin binds to the N-terminal domain of the cardiac sodium channel Na1.5. Channels (Austin, Tex.). 14: 268-286. PMID 32815768 DOI: 10.1080/19336950.2020.1805999  1
2020 Vermij SH, Rougier JS, Agulló-Pascual E, Rothenberg E, Delmar M, Abriel H. Single-molecule Localization of Na1.5 Reveals Different Modes of Reorganization at Cardiomyocyte Membrane Domains. Circulation. Arrhythmia and Electrophysiology. PMID 32536203 DOI: 10.1161/CIRCEP.119.008241  1
2019 Gillet L, Guichard S, Essers MC, Rougier JS, Abriel H. Dystrophin and calcium current are decreased in cardiomyocytes expressing Cre enzyme driven by αMHC but not TNT promoter. Scientific Reports. 9: 19422. PMID 31857666 DOI: 10.1038/s41598-019-55950-w  1
2019 Casini S, Albesa M, Wang Z, Portero V, Ross-Kaschitza D, Rougier JS, Marchal GA, Chung WK, Bezzina CR, Abriel H, Remme CA. Functional Consequences of the -p.Y1977N Mutation within the PY Ubiquitylation Motif: Discrepancy between HEK293 Cells and Transgenic Mice. International Journal of Molecular Sciences. 20. PMID 31614475 DOI: 10.3390/ijms20205033  1
2019 Neubauer J, Wang Z, Rougier JS, Abriel H, Rieubland C, Bartholdi D, Haas C, Medeiros-Domingo A. Functional characterization of a novel SCN5A variant associated with long QT syndrome and sudden cardiac death. International Journal of Legal Medicine. PMID 31455979 DOI: 10.1007/s00414-019-02141-x  1
2019 Rougier JS, Essers MC, Gillet L, Guichard S, Sonntag S, Shmerling D, Abriel H. A Distinct Pool of Na1.5 Channels at the Lateral Membrane of Murine Ventricular Cardiomyocytes. Frontiers in Physiology. 10: 834. PMID 31333492 DOI: 10.3389/fphys.2019.00834  1
2018 Tamo L, Hibaoui Y, Kallol S, Alves MP, Albrecht C, Hostettler KE, Feki A, Rougier JS, Abriel H, Knudsen L, Gazdhar A, Geiser T. Generation of an alveolar epithelial type II cell line from induced pluripotent stem cells. American Journal of Physiology. Lung Cellular and Molecular Physiology. PMID 30211653 DOI: 10.1152/ajplung.00357.2017  1
2018 Neubauer J, Rougier JS, Abriel H, Haas C. Functional implications of a rare variant in the sodium channel β1B subunit () in a 5-month-old male sudden infant death syndrome case. Heartrhythm Case Reports. 4: 187-190. PMID 29915715 DOI: 10.1016/j.hrcr.2018.01.010  1
2017 Hinard V, Britan A, Schaeffer M, Zahn-Zabal M, Thomet U, Rougier JS, Bairoch A, Abriel H, Gaudet P. Annotation of functional impact of voltage-gated sodium channel mutations. Human Mutation. PMID 28168870 DOI: 10.1002/humu.23191  1
2016 Eichel CA, Beuriot A, Chevalier MY, Rougier JS, Louault F, Dilanian G, Amour J, Coulombe A, Abriel H, Hatem SN, Balse E. Lateral Membrane-Specific MAGUK CASK Down-Regulates NaV1.5 Channel in Cardiac Myocytes. Circulation Research. 119: 544-56. PMID 27364017 DOI: 10.1161/CIRCRESAHA.116.309254  1
2016 Syam N, Chatel S, Ozhathil LC, Sottas V, Rougier JS, Baruteau A, Baron E, Amarouch MY, Daumy X, Probst V, Schott JJ, Abriel H. Variants of Transient Receptor Potential Melastatin Member 4 in Childhood Atrioventricular Block. Journal of the American Heart Association. 5. PMID 27207958 DOI: 10.1161/JAHA.114.001625  1
2016 Rougier JS, Abriel H. Cardiac voltage-gated calcium channel macromolecular complexes. Biochimica Et Biophysica Acta. 1863: 1806-12. PMID 26707467 DOI: 10.1016/j.bbamcr.2015.12.014  1
2015 Abriel H, Rougier JS, Jalife J. Ion channel macromolecular complexes in cardiomyocytes: roles in sudden cardiac death. Circulation Research. 116: 1971-88. PMID 26044251 DOI: 10.1161/CIRCRESAHA.116.305017  1
2015 Gillet L, Rougier JS, Shy D, Sonntag S, Mougenot N, Essers M, Shmerling D, Balse E, Hatem SN, Abriel H. Cardiac-specific ablation of synapse-associated protein SAP97 in mice decreases potassium currents but not sodium current. Heart Rhythm : the Official Journal of the Heart Rhythm Society. 12: 181-92. PMID 25447080 DOI: 10.1016/j.hrthm.2014.09.057  1
2015 Rougier JS, Albesa M, Syam N, Halet G, Abriel H, Viard P. Ubiquitin-specific protease USP2-45 acts as a molecular switch to promote α2δ-1-induced downregulation of Cav1.2 channels. Pflugers Archiv : European Journal of Physiology. 467: 1919-29. PMID 25366495 DOI: 10.1007/s00424-014-1636-6  1
2014 Shy D, Gillet L, Ogrodnik J, Albesa M, Verkerk AO, Wolswinkel R, Rougier JS, Barc J, Essers MC, Syam N, Marsman RF, van Mil AM, Rotman S, Redon R, Bezzina CR, et al. PDZ domain-binding motif regulates cardiomyocyte compartment-specific NaV1.5 channel expression and function. Circulation. 130: 147-60. PMID 24895455 DOI: 10.1161/CIRCULATIONAHA.113.007852  0.72
2014 Syam N, Rougier JS, Abriel H. Glycosylation of TRPM4 and TRPM5 channels: molecular determinants and functional aspects. Frontiers in Cellular Neuroscience. 8: 52. PMID 24605085 DOI: 10.3389/fncel.2014.00052  1
2013 Reinhard K, Rougier JS, Ogrodnik J, Abriel H. Electrophysiological properties of mouse and epitope-tagged human cardiac sodium channel Na v1.5 expressed in HEK293 cells. F1000research. 2: 48. PMID 24555036 DOI: 10.12688/f1000research.2-48.v2  0.72
2013 Abriel H, Rougier JS. β-blockers in congenital short-QT syndrome as ion channel blockers. Journal of Cardiovascular Electrophysiology. 24: 1172-4. PMID 23890274 DOI: 10.1111/jce.12204  1
2013 Sottas V, Rougier JS, Jousset F, Kucera JP, Shestak A, Makarov LM, Zaklyazminskaya EV, Abriel H. Characterization of 2 genetic variants of Na(v) 1.5-arginine 689 found in patients with cardiac arrhythmias. Journal of Cardiovascular Electrophysiology. 24: 1037-46. PMID 23692053 DOI: 10.1111/jce.12173  1
2013 Rougier JS, Gavillet B, Abriel H. Proteasome inhibitor (MG132) rescues Nav1.5 protein content and the cardiac sodium current in dystrophin-deficient mdx (5cv) mice. Frontiers in Physiology. 4: 51. PMID 23532763 DOI: 10.3389/fphys.2013.00051  1
2012 Rougier JS, Abriel H. Role of "non-cardiac" voltage-gated sodium channels in cardiac cells. Journal of Molecular and Cellular Cardiology. 53: 589-90. PMID 22967322 DOI: 10.1016/j.yjmcc.2012.08.011  1
2012 Rougier JS, Abriel H. Unexpected dominance: Brugada syndrome SCN5A variants exert negative dominance via α-subunit interaction. Cardiovascular Research. 96: 1-3. PMID 22871588 DOI: 10.1093/cvr/cvs264  1
2012 Abriel H, Syam N, Sottas V, Amarouch MY, Rougier JS. TRPM4 channels in the cardiovascular system: physiology, pathophysiology, and pharmacology. Biochemical Pharmacology. 84: 873-81. PMID 22750058 DOI: 10.1016/j.bcp.2012.06.021  1
2011 Templin C, Ghadri JR, Rougier JS, Baumer A, Kaplan V, Albesa M, Sticht H, Rauch A, Puleo C, Hu D, Barajas-Martinez H, Antzelevitch C, Lüscher TF, Abriel H, Duru F. Identification of a novel loss-of-function calcium channel gene mutation in short QT syndrome (SQTS6). European Heart Journal. 32: 1077-88. PMID 21383000 DOI: 10.1093/eurheartj/ehr076  1
2011 Rougier JS, Albesa M, Abriel H, Viard P. Neuronal precursor cell-expressed developmentally down-regulated 4-1 (NEDD4-1) controls the sorting of newly synthesized Ca(V)1.2 calcium channels. The Journal of Biological Chemistry. 286: 8829-38. PMID 21220429 DOI: 10.1074/jbc.M110.166520  1
2011 Albesa M, Ogrodnik J, Rougier JS, Abriel H. Regulation of the cardiac sodium channel Nav1.5 by utrophin in dystrophin-deficient mice. Cardiovascular Research. 89: 320-8. PMID 20952415 DOI: 10.1093/cvr/cvq326  0.72
2010 Rougier JS, Albesa M, Abriel H. Ubiquitylation and SUMOylation of cardiac ion channels. Journal of Cardiovascular Pharmacology. 56: 22-8. PMID 20224423 DOI: 10.1097/FJC.0b013e3181daaff9  1
2010 Leoni AL, Gavillet B, Rougier JS, Marionneau C, Probst V, Le Scouarnec S, Schott JJ, Demolombe S, Bruneval P, Huang CL, Colledge WH, Grace AA, Le Marec H, Wilde AA, Mohler PJ, et al. Variable Na(v)1.5 protein expression from the wild-type allele correlates with the penetrance of cardiac conduction disease in the Scn5a(+/-) mouse model. Plos One. 5: e9298. PMID 20174578 DOI: 10.1371/journal.pone.0009298  0.72
2008 Rougier JS, Muller O, Berger S, Centeno G, Schütz G, Firsov D, Abriel H. Mineralocorticoid receptor is essential for corticosteroid-induced up-regulation of L-type calcium currents in cultured neonatal cardiomyocytes. PflüGers Archiv : European Journal of Physiology. 456: 407-12. PMID 18040710 DOI: 10.1007/s00424-007-0387-z  0.72
2007 Kranjcec D, Bergovec M, Rougier JS, Raguz M, Pavlovic S, Jespersen T, Castella V, Keller DI, Abriel H. Brugada syndrome unmasked by accidental inhalation of gasoline vapors. Pacing and Clinical Electrophysiology : Pace. 30: 1294-8. PMID 17897138 DOI: 10.1111/j.1540-8159.2007.00857.x  1
2006 Gavillet B, Rougier JS, Domenighetti AA, Behar R, Boixel C, Ruchat P, Lehr HA, Pedrazzini T, Abriel H. Cardiac sodium channel Nav1.5 is regulated by a multiprotein complex composed of syntrophins and dystrophin Circulation Research. 99: 407-414. PMID 16857961 DOI: 10.1161/01.RES.0000237466.13252.5e  0.72
2006 Fodstad H, Bendahhou S, Rougier JS, Laitinen-Forsblom PJ, Barhanin J, Abriel H, Schild L, Kontula K, Swan H. Molecular characterization of two founder mutations causing long QT syndrome and identification of compound heterozygous patients. Annals of Medicine. 38: 294-304. PMID 16754261 DOI: 10.1080/07853890600756065  0.72
2006 Camacho JA, Hensellek S, Rougier JS, Blechschmidt S, Abriel H, Benndorf K, Zimmer T. Modulation of Nav1.5 channel function by an alternatively spliced sequence in the DII/DIII linker region. The Journal of Biological Chemistry. 281: 9498-506. PMID 16469732 DOI: 10.1074/jbc.M509716200  1
2006 Boixel C, Gavillet B, Rougier JS, Abriel H. Aldosterone increases voltage-gated sodium current in ventricular myocytes. American Journal of Physiology. Heart and Circulatory Physiology. 290: H2257-66. PMID 16428353 DOI: 10.1152/ajpheart.01060.2005  1
2005 Keller DI, Rougier JS, Kucera JP, Benammar N, Fressart V, Guicheney P, Madle A, Fromer M, Schläpfer J, Abriel H. Brugada syndrome and fever: genetic and molecular characterization of patients carrying SCN5A mutations. Cardiovascular Research. 67: 510-9. PMID 15890323 DOI: 10.1016/j.cardiores.2005.03.024  1
2005 Rougier JS, van Bemmelen MX, Bruce MC, Jespersen T, Gavillet B, Apothéloz F, Cordonier S, Staub O, Rotin D, Abriel H. Molecular determinants of voltage-gated sodium channel regulation by the Nedd4/Nedd4-like proteins. American Journal of Physiology. Cell Physiology. 288: C692-701. PMID 15548568 DOI: 10.1152/ajpcell.00460.2004  0.72
2004 van Bemmelen MX, Rougier JS, Gavillet B, Apothéloz F, Daidié D, Tateyama M, Rivolta I, Thomas MA, Kass RS, Staub O, Abriel H. Cardiac voltage-gated sodium channel Nav1.5 is regulated by Nedd4-2 mediated ubiquitination. Circulation Research. 95: 284-91. PMID 15217910 DOI: 10.1161/01.RES.0000136816.05109.89  0.72
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