Denis Guilloteau - Publications

Affiliations: 
Universite de Tours 

107 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Vala C, Mothes C, Chicheri G, Magadur P, Viot G, Deloye JB, Maia S, Bouvet Y, Dupont AC, Arlicot N, Guilloteau D, Emond P, Vercouillie J. Fully automated radiosynthesis of [F]LBT999 on TRACERlab FX and AllinOne modules, a PET radiopharmaceutical for imaging the dopamine transporter in human brain. Ejnmmi Radiopharmacy and Chemistry. 5: 26. PMID 33196944 DOI: 10.1186/s41181-020-00105-w  0.88
2020 Ribeiro MJ, Vercouillie J, Arlicot N, Tauber C, Gissot V, Mondon K, Barantin L, Cottier JP, Maia S, Deloye JB, Emond P, Guilloteau D. Usefulness of PET With [F]LBT-999 for the Evaluation of Presynaptic Dopaminergic Neuronal Loss in a Clinical Environment. Frontiers in Neurology. 11: 754. PMID 32973645 DOI: 10.3389/fneur.2020.00754  0.88
2019 Arlicot N, Vercouillie J, Malherbe C, Bidault R, Gissot V, Maia S, Barantin L, Cottier JP, Deloye JB, Guilloteau D, Ribeiro MJ. PET imaging of Dopamine Transporter with [18F]LBT-999: initial evaluation in healthy volunteers. The Quarterly Journal of Nuclear Medicine and Molecular Imaging : Official Publication of the Italian Association of Nuclear Medicine (Aimn) [and] the International Association of Radiopharmacology (Iar), [and] Section of the Society of.... PMID 31496203 DOI: 10.23736/S1824-4785.19.03175-3  0.88
2019 Ouach A, Vercouillie J, Bertrand E, Rodrigues N, Pin F, Serriere S, Boiaryna L, Chartier A, Percina N, Tangpong P, Gulhan Z, Mothes C, Deloye JB, Guilloteau D, Page G, et al. Bis(het)aryl-1,2,3-triazole quinuclidines as α7 nicotinic acetylcholine receptor ligands: Synthesis, structure affinity relationships, agonism activity, [F]-radiolabeling and PET study in rats. European Journal of Medicinal Chemistry. 179: 449-469. PMID 31271958 DOI: 10.1016/j.ejmech.2019.06.049  0.48
2019 Chalon S, Vercouillie J, Payoux P, Deloye JB, Malherbe C, Le Jeune F, Arlicot N, Salabert AS, Guilloteau D, Emond P, Ribeiro MJ. The Story of the Dopamine Transporter PET Tracer LBT-999: From Conception to Clinical Use. Frontiers in Medicine. 6: 90. PMID 31131278 DOI: 10.3389/fmed.2019.00090  0.88
2019 Elie J, Vercouillie J, Arlicot N, Lemaire L, Bidault R, Bodard S, Hosselet C, Deloye JB, Chalon S, Emond P, Guilloteau D, Buron F, Routier S. Design of selective COX-2 inhibitors in the (aza)indazole series. Chemistry, in vitro studies, radiochemistry and evaluations in rats of a [F] PET tracer. Journal of Enzyme Inhibition and Medicinal Chemistry. 34: 1-7. PMID 30362376 DOI: 10.1080/14756366.2018.1501043  0.88
2018 Dupont AC, Largeau B, Guilloteau D, Santiago Ribeiro MJ, Arlicot N. The Place of PET to Assess New Therapeutic Effectiveness in Neurodegenerative Diseases. Contrast Media & Molecular Imaging. 2018: 7043578. PMID 29887768 DOI: 10.1155/2018/7043578  0.88
2017 Largeau B, Dupont AC, Guilloteau D, Santiago-Ribeiro MJ, Arlicot N. TSPO PET Imaging: From Microglial Activation to Peripheral Sterile Inflammatory Diseases? Contrast Media & Molecular Imaging. 2017: 6592139. PMID 29114179 DOI: 10.1155/2017/6592139  0.88
2017 Tronel C, Largeau B, Santiago Ribeiro MJ, Guilloteau D, Dupont AC, Arlicot N. Molecular Targets for PET Imaging of Activated Microglia: The Current Situation and Future Expectations. International Journal of Molecular Sciences. 18. PMID 28398245 DOI: 10.3390/ijms18040802  0.88
2017 Dupont AC, Largeau B, Santiago Ribeiro MJ, Guilloteau D, Tronel C, Arlicot N. Translocator Protein-18 kDa (TSPO) Positron Emission Tomography (PET) Imaging and Its Clinical Impact in Neurodegenerative Diseases. International Journal of Molecular Sciences. 18. PMID 28387722 DOI: 10.3390/ijms18040785  0.88
2016 Barbet J, Arlicot N, Gaugler MH, Chérel M, Guilloteau D, Kraeber-Bodéré F. Editorial: Innovative Radiopharmaceuticals in Oncology and Neurology. Frontiers in Medicine. 3: 74. PMID 28123998 DOI: 10.3389/fmed.2016.00074  0.88
2016 Thomas C, Vercouillie J, Doméné A, Tauber C, Kassiou M, Guilloteau D, Destrieux C, Sérrière S, Chalon S. Detection of Neuroinflammation in a Rat Model of Subarachnoid Hemorrhage Using [18F]DPA-714 PET Imaging. Molecular Imaging. 15. PMID 27118758 DOI: 10.1177/1536012116639189  0.48
2016 Ouach A, Pin F, Bertrand E, Vercouillie J, Gulhan Z, Mothes C, Deloye JB, Guilloteau D, Suzenet F, Chalon S, Routier S. Design of α7 nicotinic acetylcholine receptor ligands using the (het)Aryl-1,2,3-triazole core: Synthesis, in vitro evaluation and SAR studies. European Journal of Medicinal Chemistry. 107: 153-64. PMID 26580980 DOI: 10.1016/j.ejmech.2015.11.001  0.48
2015 Sérrière S, Doméné A, Vercouillie J, Mothes C, Bodard S, Rodrigues N, Guilloteau D, Routier S, Page G, Chalon S. Assessment of the Protection of Dopaminergic Neurons by an α7 Nicotinic Receptor Agonist, PHA 543613 Using [(18)F]LBT-999 in a Parkinson's Disease Rat Model. Frontiers in Medicine. 2: 61. PMID 26389120 DOI: 10.3389/fmed.2015.00061  0.48
2015 Gourand F, Amini N, Jia Z, Stone-Elander S, Guilloteau D, Barré L, Halldin C. [11C]MADAM Used as a Model for Understanding the Radiometabolism of Diphenyl Sulfide Radioligands for Positron Emission Tomography (PET). Plos One. 10: e0137160. PMID 26367261 DOI: 10.1371/journal.pone.0137160  0.32
2015 Jensen P, Feng L, Law I, Svarer C, Knudsen GM, Mikkelsen JD, de Nijs R, Larsen VA, Dyssegaard A, Thomsen G, Fischer W, Guilloteau D, Pinborg LH. TSPO Imaging in Glioblastoma Multiforme: A Direct Comparison Between 123I-CLINDE SPECT, 18F-FET PET, and Gadolinium-Enhanced MR Imaging. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. 56: 1386-90. PMID 26182972 DOI: 10.2967/jnumed.115.158998  0.32
2015 Sérrière S, Tauber C, Vercouillie J, Mothes C, Pruckner C, Guilloteau D, Kassiou M, Doméné A, Garreau L, Page G, Chalon S. Amyloid load and translocator protein 18 kDa in APPswePS1-dE9 mice: a longitudinal study. Neurobiology of Aging. 36: 1639-52. PMID 25680265 DOI: 10.1016/j.neurobiolaging.2014.11.023  0.48
2015 Dufour-Rainfray D, Moal V, Cloix L, Mathieu E, Gauchez AS, Brossaud J, Corcuff JB, Fraissinet F, Collet C, De Casson FB, Guilloteau D, Emond P, Reynier P, Bach K, Charrié A, et al. Mass spectrometry for steroid assays | Dosages des stéroïdes par spectrométrie de masse Annales De Biologie Clinique. 73: 70-78. DOI: 10.1684/abc.2014.0988  0.32
2014 Arlicot N, Tronel C, Bodard S, Garreau L, de la Crompe B, Vandevelde I, Guilloteau D, Antier D, Chalon S. Translocator Protein (18 kDa) Mapping with [(125)I]-CLINDE in the Quinolinic Acid Rat Model of Excitotoxicity: A Longitudinal Comparison with Microglial Activation, Astrogliosis, and Neuronal Death. Molecular Imaging. 13: 7290201300075. PMID 28650286 DOI: 10.2310/7290.2013.00075  0.88
2014 Jaouen V, González P, Stute S, Guilloteau D, Chalon S, Buvat I, Tauber C. Variational segmentation of vector-valued images with gradient vector flow. Ieee Transactions On Image Processing : a Publication of the Ieee Signal Processing Society. 23: 4773-85. PMID 25203991 DOI: 10.1109/TIP.2014.2353854  0.48
2014 Ribeiro MJ, Vercouillie J, Debiais S, Cottier JP, Bonnaud I, Camus V, Banister S, Kassiou M, Arlicot N, Guilloteau D. Could (18) F-DPA-714 PET imaging be interesting to use in the early post-stroke period? Ejnmmi Research. 4: 28. PMID 25006546 DOI: 10.1186/s13550-014-0028-4  0.88
2014 Pin F, Vercouillie J, Ouach A, Mavel S, Gulhan Z, Chicheri G, Jarry C, Massip S, Deloye JB, Guilloteau D, Suzenet F, Chalon S, Routier S. Design of α7 nicotinic acetylcholine receptor ligands in quinuclidine, tropane and quinazoline series. Chemistry, molecular modeling, radiochemistry, in vitro and in rats evaluations of a [(18)F] quinuclidine derivative. European Journal of Medicinal Chemistry. 82: 214-24. PMID 24904968 DOI: 10.1016/j.ejmech.2014.04.057  0.48
2014 Gourand F, Emond P, Bergström JP, Takano A, Gulyás B, Guilloteau D, Barré L, Halldin C. A radiometabolite study of the serotonin transporter PET radioligand [(11)C]MADAM. Nuclear Medicine and Biology. 41: 501-6. PMID 24857865 DOI: 10.1016/j.nucmedbio.2014.03.022  0.32
2014 Arlicot N, Tronel C, Bodard S, Garreau L, de la Crompe B, Vandevelde I, Guilloteau D, Antier D, Chalon S. Translocator protein (18 kDa) mapping with [125I]-CLINDE in the quinolinic acid rat model of excitotoxicity: a longitudinal comparison with microglial activation, astrogliosis, and neuronal death. Molecular Imaging. 13: 4-11. PMID 24622813  0.88
2014 Sérrière S, Tauber C, Vercouillie J, Guilloteau D, Deloye JB, Garreau L, Galineau L, Chalon S. In vivo PET quantification of the dopamine transporter in rat brain with [¹⁸F]LBT-999. Nuclear Medicine and Biology. 41: 106-13. PMID 24210285 DOI: 10.1016/j.nucmedbio.2013.09.007  0.48
2014 Hommet C, Mondon K, Camus V, Ribeiro MJ, Beaufils E, Arlicot N, Corcia P, Paccalin M, Minier F, Gosselin T, Page G, Guilloteau D, Chalon S. Neuroinflammation and β amyloid deposition in Alzheimer's disease: in vivo quantification with molecular imaging. Dementia and Geriatric Cognitive Disorders. 37: 1-18. PMID 24107621 DOI: 10.1159/000354363  0.88
2013 Martins AF, Morfin JF, Kubí?ková A, Kubí?ek V, Buron F, Suzenet F, Salerno M, Lazar AN, Duyckaerts C, Arlicot N, Guilloteau D, Geraldes CF, Tóth E. PiB-Conjugated, Metal-Based Imaging Probes: Multimodal Approaches for the Visualization of β-Amyloid Plaques. Acs Medicinal Chemistry Letters. 4: 436-40. PMID 24900692 DOI: 10.1021/ml400042w  0.88
2013 Dufour-Rainfray D, Beaufils E, Vourc'h P, Vierron E, Mereghetti L, Gendrot C, Hommet C, Andres CR, Guilloteau D, Mondon K. Total protein level in cerebrospinal fluid is stable in elderly adults. Journal of the American Geriatrics Society. 61: 1819-21. PMID 24117297 DOI: 10.1111/jgs.12489  0.32
2012 Corcia P, Tauber C, Vercoullie J, Arlicot N, Prunier C, Praline J, Nicolas G, Venel Y, Hommet C, Baulieu JL, Cottier JP, Roussel C, Kassiou M, Guilloteau D, Ribeiro MJ. Molecular imaging of microglial activation in amyotrophic lateral sclerosis. Plos One. 7: e52941. PMID 23300829 DOI: 10.1371/journal.pone.0052941  0.88
2012 Mazère J, Meissner WG, Mayo W, Sibon I, Lamare F, Guilloteau D, Tison F, Allard M. Progressive supranuclear palsy: in vivo SPECT imaging of presynaptic vesicular acetylcholine transporter with [123I]-iodobenzovesamicol. Radiology. 265: 537-43. PMID 23012462 DOI: 10.1148/radiol.12112650  0.32
2012 Leaver KR, Reynolds A, Bodard S, Guilloteau D, Chalon S, Kassiou M. Effects of translocator protein (18 kDa) ligands on microglial activation and neuronal death in the quinolinic-acid-injected rat striatum. Acs Chemical Neuroscience. 3: 114-9. PMID 22860181 DOI: 10.1021/cn200099e  0.48
2012 Maia S, Arlicot N, Vierron E, Bodard S, Vergote J, Guilloteau D, Chalon S. Longitudinal and parallel monitoring of neuroinflammation and neurodegeneration in a 6-hydroxydopamine rat model of Parkinson's disease. Synapse (New York, N.Y.). 66: 573-83. PMID 22337286 DOI: 10.1002/syn.21543  0.88
2012 Arlicot N, Vercouillie J, Ribeiro MJ, Tauber C, Venel Y, Baulieu JL, Maia S, Corcia P, Stabin MG, Reynolds A, Kassiou M, Guilloteau D. Initial evaluation in healthy humans of [18F]DPA-714, a potential PET biomarker for neuroinflammation. Nuclear Medicine and Biology. 39: 570-8. PMID 22172392 DOI: 10.1016/j.nucmedbio.2011.10.012  0.88
2011 Le Pogam A, Hatt M, Descourt P, Boussion N, Tsoumpas C, Turkheimer FE, Prunier-Aesch C, Baulieu JL, Guilloteau D, Visvikis D. Evaluation of a 3D local multiresolution algorithm for the correction of partial volume effects in positron emission tomography. Medical Physics. 38: 4920-3. PMID 21978037 DOI: 10.1118/1.3608907  0.32
2011 Tauber C, Stute S, Chau M, Spiteri P, Chalon S, Guilloteau D, Buvat I. Spatio-temporal diffusion of dynamic PET images. Physics in Medicine and Biology. 56: 6583-96. PMID 21937774 DOI: 10.1088/0031-9155/56/20/004  0.48
2011 Varrone A, Stepanov V, Nakao R, Tóth M, Gulyás B, Emond P, Deloye JB, Vercouillie J, Stabin MG, Jonsson C, Guilloteau D, Halldin C. Imaging of the striatal and extrastriatal dopamine transporter with (18)F-LBT-999: quantification, biodistribution, and radiation dosimetry in nonhuman primates. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. 52: 1313-21. PMID 21764797 DOI: 10.2967/jnumed.111.089953  0.32
2011 Dufour-Rainfray D, Vourc'h P, Tourlet S, Guilloteau D, Chalon S, Andres CR. Fetal exposure to teratogens: evidence of genes involved in autism. Neuroscience and Biobehavioral Reviews. 35: 1254-65. PMID 21195109 DOI: 10.1016/j.neubiorev.2010.12.013  0.32
2011 Varrone A, Tóth M, Steiger C, Takano A, Guilloteau D, Ichise M, Gulyás B, Halldin C. Kinetic analysis and quantification of the dopamine transporter in the nonhuman primate brain with 11C-PE2I and 18F-FE-PE2I. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. 52: 132-9. PMID 21189414 DOI: 10.2967/jnumed.110.077651  0.32
2010 Arlicot N, Petit E, Katsifis A, Toutain J, Divoux D, Bodard S, Roussel S, Guilloteau D, Bernaudin M, Chalon S. Detection and quantification of remote microglial activation in rodent models of focal ischaemia using the TSPO radioligand CLINDE. European Journal of Nuclear Medicine and Molecular Imaging. 37: 2371-80. PMID 20814674 DOI: 10.1007/s00259-010-1598-7  0.88
2010 Song PJ, Barc C, Arlicot N, Guilloteau D, Bernard S, Sarradin P, Chalon S, Garreau L, Kung HF, Lantier F, Vergote J. Evaluation of prion deposits and microglial activation in scrapie-infected mice using molecular imaging probes. Molecular Imaging and Biology : Mib : the Official Publication of the Academy of Molecular Imaging. 12: 576-82. PMID 20376566 DOI: 10.1007/s11307-010-0321-1  0.32
2010 Dufour-Rainfray D, Vourc'h P, Le Guisquet AM, Garreau L, Ternant D, Bodard S, Jaumain E, Gulhan Z, Belzung C, Andres CR, Chalon S, Guilloteau D. Behavior and serotonergic disorders in rats exposed prenatally to valproate: a model for autism. Neuroscience Letters. 470: 55-9. PMID 20036713 DOI: 10.1016/j.neulet.2009.12.054  0.32
2009 Schou M, Steiger C, Varrone A, Guilloteau D, Halldin C. Synthesis, radiolabeling and preliminary in vivo evaluation of [18F]FE-PE2I, a new probe for the dopamine transporter. Bioorganic & Medicinal Chemistry Letters. 19: 4843-5. PMID 19577467 DOI: 10.1016/j.bmcl.2009.06.032  0.32
2009 Varrone A, Steiger C, Schou M, Takano A, Finnema SJ, Guilloteau D, Gulyás B, Halldin C. In vitro autoradiography and in vivo evaluation in cynomolgus monkey of [18F]FE-PE2I, a new dopamine transporter PET radioligand. Synapse (New York, N.Y.). 63: 871-80. PMID 19562698 DOI: 10.1002/syn.20670  0.32
2009 Vergote J, Chalon S, Emond P, Vercouillie J, Pappata S, Guilloteau D. New SPECT and PET dementia tracers | Les nouveaux traceurs TEMP et TEP de la démence Medecine Nucleaire. 33: 137-141. DOI: 10.1016/j.mednuc.2009.01.005  0.32
2008 Heuland E, Galineau L, Le Guisquet AM, Garreau L, Guilloteau D, Belzung C, Chalon S. WITHDRAWN: Prenatal exposure to MDMA induces sex-dependent and region-specific modifications in brain dopamine systems at adult age in the rat. International Journal of Developmental Neuroscience : the Official Journal of the International Society For Developmental Neuroscience. PMID 19118618 DOI: 10.1016/j.ijdevneu.2008.12.001  0.48
2008 Mavel S, Vercouillie J, Garreau L, Raguza T, Ravna AW, Chalon S, Guilloteau D, Emond P. Docking study, synthesis, and in vitro evaluation of fluoro-MADAM derivatives as SERT ligands for PET imaging. Bioorganic & Medicinal Chemistry. 16: 9050-5. PMID 18793858 DOI: 10.1016/j.bmc.2008.08.002  0.48
2008 Arlicot N, Katsifis A, Garreau L, Mattner F, Vergote J, Duval S, Kousignian I, Bodard S, Guilloteau D, Chalon S. Evaluation of CLINDE as potent translocator protein (18 kDa) SPECT radiotracer reflecting the degree of neuroinflammation in a rat model of microglial activation. European Journal of Nuclear Medicine and Molecular Imaging. 35: 2203-11. PMID 18536913 DOI: 10.1007/s00259-008-0834-x  0.88
2008 Emond P, Guilloteau D, Chalon S. PE2I: a radiopharmaceutical for in vivo exploration of the dopamine transporter. Cns Neuroscience & Therapeutics. 14: 47-64. PMID 18482099 DOI: 10.1111/j.1527-3458.2007.00033.x  0.48
2008 James ML, Fulton RR, Vercoullie J, Henderson DJ, Garreau L, Chalon S, Dolle F, Costa B, Selleri S, Guilloteau D, Kassiou M. DPA-714, a new translocator protein-specific ligand: synthesis, radiofluorination, and pharmacologic characterization. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. 49: 814-22. PMID 18413395 DOI: 10.2967/jnumed.107.046151  0.32
2008 Bouchez G, Sensebé L, Vourc'h P, Garreau L, Bodard S, Rico A, Guilloteau D, Charbord P, Besnard JC, Chalon S. Partial recovery of dopaminergic pathway after graft of adult mesenchymal stem cells in a rat model of Parkinson's disease. Neurochemistry International. 52: 1332-42. PMID 18372079 DOI: 10.1016/j.neuint.2008.02.003  0.48
2008 Song PJ, Bernard S, Sarradin P, Vergote J, Barc C, Chalon S, Kung MP, Kung HF, Guilloteau D. IMPY, a potential beta-amyloid imaging probe for detection of prion deposits in scrapie-infected mice. Nuclear Medicine and Biology. 35: 197-201. PMID 18312829 DOI: 10.1016/j.nucmedbio.2007.10.005  0.48
2008 Chitneni SK, Garreau L, Cleynhens B, Evens N, Bex M, Vermaelen P, Chalon S, Busson R, Guilloteau D, Van Laere K, Verbruggen A, Bormans G. Improved synthesis and metabolic stability analysis of the dopamine transporter ligand [(18)F]FECT. Nuclear Medicine and Biology. 35: 75-82. PMID 18158946 DOI: 10.1016/j.nucmedbio.2007.09.001  0.48
2008 Arlicot N, Katsifis A, Garreau L, Mattner F, Vergote J, Duval S, Kousignian I, Bodard S, Guilloteau D, Chalon S. Evaluation of CLINDE as potent translocator protein (18 kDa) SPECT radiotracer reflecting the degree of neuroinflammation in a rat model of microglial activation (European Journal of Nuclear Medicine and Molecular Imaging DOI: 10.1007/s00259-008-0834-x) European Journal of Nuclear Medicine and Molecular Imaging. 35: 2341. DOI: 10.1007/s00259-008-0882-2  0.32
2007 Emond P, Mavel S, Zea-Ponce Y, Kassiou M, Garreau L, Bodard S, Drossard ML, Chalon S, Guilloteau D. (E)-[125I]-5-AOIBV: a SPECT radioligand for the vesicular acetylcholine transporter. Nuclear Medicine and Biology. 34: 967-71. PMID 17998100 DOI: 10.1016/j.nucmedbio.2007.07.011  0.48
2007 Giboureau N, Emond P, Fulton RR, Henderson DJ, Chalon S, Garreau L, Roselt P, Eberl S, Mavel S, Bodard S, Fulham MJ, Guilloteau D, Kassiou M. Ex vivo and in vivo evaluation of (2R,3R)-5-[(18)F]-fluoroethoxy- and fluoropropoxy-benzovesamicol, as PET radioligands for the vesicular acetylcholine transporter. Synapse (New York, N.Y.). 61: 962-70. PMID 17787004 DOI: 10.1002/syn.20450  0.32
2007 Vercouillie J, Deuther-Conrad W, Scheunemann M, Emond P, Fischer S, Funke U, Steinbach J, Guilloteau D, Brust P. New fluoro-diphenylchalcogen derivatives to explore the serotonin transporter by PET. Bioorganic & Medicinal Chemistry Letters. 17: 4991-5. PMID 17658253 DOI: 10.1016/j.bmcl.2007.02.082  0.48
2007 Baulieu F, Boiron M, Bertrand P, Guilloteau D, Baulieu JL, Metman EH. Evaluation of a solid bolus suitable for esophageal scintigraphy. Dysphagia. 22: 281-9. PMID 17554473 DOI: 10.1007/s00455-007-9083-6  0.32
2007 Quinlivan M, Chalon S, Vergote J, Henderson J, Katsifis A, Kassiou M, Guilloteau D. Decreased vesicular acetylcholine transporter and alpha(4)beta(2) nicotinic receptor density in the rat brain following 192 IgG-saporin immunolesioning. Neuroscience Letters. 415: 97-101. PMID 17339079 DOI: 10.1016/j.neulet.2006.08.065  0.48
2007 Kozikowski AP, Chellappan SK, Henderson D, Fulton R, Giboureau N, Xiao Y, Wei ZL, Guilloteau D, Emond P, Dolle F, Kellar KJ, Kassiou M. Acetylenic pyridines for use in PET imaging of nicotinic receptors. Chemmedchem. 2: 54-7. PMID 17096450 DOI: 10.1002/cmdc.200600220  0.32
2007 Saba W, Valette H, Schöllhorn-Peyronneau MA, Coulon C, Ottaviani M, Chalon S, Dolle F, Emond P, Halldin C, Helfenbein J, Madelmont JC, Deloye JB, Guilloteau D, Bottlaender M. [11C]LBT-999: a suitable radioligand for investigation of extra-striatal dopamine transporter with PET. Synapse (New York, N.Y.). 61: 17-23. PMID 17068778 DOI: 10.1002/syn.20337  0.48
2006 Magnant J, Vecellio L, de Monte M, Grimbert D, Valat C, Boissinot E, Guilloteau D, Lemarié E, Diot P. Comparative analysis of different scintigraphic approaches to assess pulmonary ventilation. Journal of Aerosol Medicine : the Official Journal of the International Society For Aerosols in Medicine. 19: 148-59. PMID 16796539 DOI: 10.1089/jam.2006.19.148  0.32
2006 Assaad T, Mavel S, Parsons SM, Kruse S, Galineau L, Allouchi H, Kassiou M, Chalon S, Guilloteau D, Emond P. Synthesis and in vitro evaluation of N-substituted aza-trozamicol analogs as vesicular acetylcholine transporter ligands. Bioorganic & Medicinal Chemistry Letters. 16: 2654-7. PMID 16516472 DOI: 10.1016/j.bmcl.2006.02.033  0.32
2006 Chalon S, Hall H, Saba W, Garreau L, Dollé F, Halldin C, Emond P, Bottlaender M, Deloye JB, Helfenbein J, Madelmont JC, Bodard S, Mincheva Z, Besnard JC, Guilloteau D. Pharmacological characterization of (E)-N-(4-fluorobut-2-enyl)-2beta-carbomethoxy-3beta-(4'-tolyl)nortropane (LBT-999) as a highly promising fluorinated ligand for the dopamine transporter. The Journal of Pharmacology and Experimental Therapeutics. 317: 147-52. PMID 16339913 DOI: 10.1124/jpet.105.096792  0.48
2006 Vercouillie J, Mavel S, Galineau L, Ragusa T, Innis R, Kassiou M, Chalon S, Dollé F, Besnard JC, Guilloteau D, Emond P. Synthesis and in vitro evaluation of novel derivatives of diphenylsulfide as serotonin transporter ligands. Bioorganic & Medicinal Chemistry Letters. 16: 1297-300. PMID 16337793 DOI: 10.1016/j.bmcl.2005.11.066  0.48
2006 Mavel S, Dikic B, Palakas S, Emond P, Greguric I, de Gracia AG, Mattner F, Garrigos M, Guilloteau D, Katsifis A. Synthesis and biological evaluation of a series of flavone derivatives as potential radioligands for imaging the multidrug resistance-associated protein 1 (ABCC1/MRP1). Bioorganic & Medicinal Chemistry. 14: 1599-607. PMID 16263302 DOI: 10.1016/j.bmc.2005.10.009  0.32
2006 Dollé F, Emond P, Mavel S, Demphel S, Hinnen F, Mincheva Z, Saba W, Valette H, Chalon S, Halldin C, Helfenbein J, Legaillard J, Madelmont JC, Deloye JB, Bottlaender M, ... Guilloteau D, et al. Synthesis, radiosynthesis and in vivo preliminary evaluation of [11C]LBT-999, a selective radioligand for the visualisation of the dopamine transporter with PET. Bioorganic & Medicinal Chemistry. 14: 1115-25. PMID 16219467 DOI: 10.1016/j.bmc.2005.09.035  0.48
2005 Halldin C, Lundberg J, Sóvágó J, Gulyás B, Guilloteau D, Vercouillie J, Emond P, Chalon S, Tarkiainen J, Hiltunen J, Farde L. [(11)C]MADAM, a new serotonin transporter radioligand characterized in the monkey brain by PET. Synapse (New York, N.Y.). 58: 173-83. PMID 16138320 DOI: 10.1002/syn.20189  0.32
2005 Galineau L, Belzung C, Kodas E, Bodard S, Guilloteau D, Chalon S. Prenatal 3,4-methylenedioxymethamphetamine (ecstasy) exposure induces long-term alterations in the dopaminergic and serotonergic functions in the rat. Brain Research. Developmental Brain Research. 154: 165-76. PMID 15707670 DOI: 10.1016/j.devbrainres.2004.10.012  0.32
2005 Zea-Ponce Y, Mavel S, Assaad T, Kruse SE, Parsons SM, Emond P, Chalon S, Giboureau N, Kassiou M, Guilloteau D. Synthesis and in vitro evaluation of new benzovesamicol analogues as potential imaging probes for the vesicular acetylcholine transporter. Bioorganic & Medicinal Chemistry. 13: 745-53. PMID 15653342 DOI: 10.1016/j.bmc.2004.10.043  0.32
2004 Ray M, Bohr I, McIntosh JM, Ballard C, McKeith I, Chalon S, Guilloteau D, Perry R, Perry E, Court JA, Piggott M. Involvement of alpha6/alpha3 neuronal nicotinic acetylcholine receptors in neuropsychiatric features of Dementia with Lewy bodies: [(125)I]-alpha-conotoxin MII binding in the thalamus and striatum. Neuroscience Letters. 372: 220-5. PMID 15542244 DOI: 10.1016/j.neulet.2004.09.042  0.32
2004 Galineau L, Kodas E, Guilloteau D, Vilar MP, Chalon S. Ontogeny of the dopamine and serotonin transporters in the rat brain: an autoradiographic study. Neuroscience Letters. 363: 266-71. PMID 15182957 DOI: 10.1016/j.neulet.2004.04.007  0.48
2004 Kodas E, Galineau L, Bodard S, Vancassel S, Guilloteau D, Besnard JC, Chalon S. Serotoninergic neurotransmission is affected by n-3 polyunsaturated fatty acids in the rat. Journal of Neurochemistry. 89: 695-702. PMID 15086526 DOI: 10.1111/j.1471-4159.2004.02401.x  0.48
2004 Chalon S, Bronquard C, Vercouillie J, Kodas E, Garreau L, Bodard S, Emond P, Besnard JC, Guilloteau D. ADAM is an effective tool for in vivo study of serotonergic function: validation in rat models. Synapse (New York, N.Y.). 52: 136-42. PMID 15034919 DOI: 10.1002/syn.20012  0.48
2003 Meissner W, Prunier C, Guilloteau D, Chalon S, Gross CE, Bezard E. Time-course of nigrostriatal degeneration in a progressive MPTP-lesioned macaque model of Parkinson's disease. Molecular Neurobiology. 28: 209-18. PMID 14709785 DOI: 10.1385/MN:28:3:209  0.32
2003 Quinlivan M, Mattner F, Papazian V, Zhou J, Katsifis A, Emond P, Chalon S, Kozikowski A, Guilloteau D, Kassiou M. Synthesis and evaluation of iodine-123 labelled tricyclic tropanes as radioligands for the serotonin transporter. Nuclear Medicine and Biology. 30: 741-6. PMID 14499332 DOI: 10.1016/S0969-8051(03)00076-3  0.48
2003 Prunier C, Bézard E, Montharu J, Mantzarides M, Besnard JC, Baulieu JL, Gross C, Guilloteau D, Chalon S. Presymptomatic diagnosis of experimental Parkinsonism with 123I-PE2I SPECT. Neuroimage. 19: 810-6. PMID 12880809 DOI: 10.1016/S1053-8119(03)00163-0  0.32
2003 Cantagrel S, Krier C, Ducrocq S, Bodard S, Payen V, Laugier J, Guilloteau D, Chalon S. Hypoxic preconditioning reduces apoptosis in a rat model of immature brain hypoxia-ischaemia. Neuroscience Letters. 347: 106-10. PMID 12873739  0.48
2003 Halldin C, Erixon-Lindroth N, Pauli S, Chou YH, Okubo Y, Karlsson P, Lundkvist C, Olsson H, Guilloteau D, Emond P, Farde L. [(11)C]PE2I: a highly selective radioligand for PET examination of the dopamine transporter in monkey and human brain. European Journal of Nuclear Medicine and Molecular Imaging. 30: 1220-30. PMID 12811422 DOI: 10.1007/s00259-003-1212-3  0.32
2003 Prunier C, Payoux P, Guilloteau D, Chalon S, Giraudeau B, Majorel C, Tafani M, Bezard E, Esquerré JP, Baulieu JL. Quantification of dopamine transporter by 123I-PE2I SPECT and the noninvasive Logan graphical method in Parkinson's disease. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. 44: 663-70. PMID 12732666  0.32
2003 Chalon S, Tarkiainen J, Garreau L, Hall H, Emond P, Vercouillie J, Farde L, Dasse P, Varnas K, Besnard JC, Halldin C, Guilloteau D. Pharmacological characterization of N,N-dimethyl-2-(2-amino-4-methylphenyl thio)benzylamine as a ligand of the serotonin transporter with high affinity and selectivity. The Journal of Pharmacology and Experimental Therapeutics. 304: 81-7. PMID 12490578 DOI: 10.1124/jpet.102.042226  0.32
2002 Sandell J, Yu M, Emond P, Garreau L, Chalon S, Någren K, Guilloteau D, Halldin C. Synthesis, radiolabeling and preliminary biological evaluation of radiolabeled 5-methyl-6-nitroquipazine, a potential radioligand for the serotonin transporter. Bioorganic & Medicinal Chemistry Letters. 12: 3611-3. PMID 12443787 DOI: 10.1016/S0960-894X(02)00787-4  0.32
2002 Sandell J, Halldin C, Sovago J, Chou YH, Gulyás B, Yu M, Emond P, Någren K, Guilloteau D, Farde L. PET examination of [(11)C]5-methyl-6-nitroquipazine, a radioligand for visualization of the serotonin transporter. Nuclear Medicine and Biology. 29: 651-6. PMID 12234589 DOI: 10.1016/S0969-8051(02)00318-9  0.32
2002 Kodas E, Vancassel S, Lejeune B, Guilloteau D, Chalon S. Reversibility of n-3 fatty acid deficiency-induced changes in dopaminergic neurotransmission in rats: critical role of developmental stage. Journal of Lipid Research. 43: 1209-19. PMID 12177165  0.48
2002 Gouhier C, Chalon S, Aubert-Pouessel A, Venier-Julienne MC, Jollivet C, Benoit JP, Guilloteau D. Protection of dopaminergic nigrostriatal afferents by GDNF delivered by microspheres in a rodent model of Parkinson's disease. Synapse (New York, N.Y.). 44: 124-31. PMID 11954043 DOI: 10.1002/syn.10063  0.48
2002 Zimmer L, Vancassel S, Cantagrel S, Breton P, Delamanche S, Guilloteau D, Durand G, Chalon S. The dopamine mesocorticolimbic pathway is affected by deficiency in n-3 polyunsaturated fatty acids. The American Journal of Clinical Nutrition. 75: 662-7. PMID 11916751  0.48
2002 Barc S, Page G, Barrier L, Garreau L, Guilloteau D, Fauconneau B, Chalon S. Relevance of different striatal markers in assessment of the MPP+-induced dopaminergic nigrostriatal injury in rat. Journal of Neurochemistry. 80: 365-74. PMID 11905985  0.48
2002 Emond P, Vercouillie J, Innis R, Chalon S, Mavel S, Frangin Y, Halldin C, Besnard JC, Guilloteau D. Substituted diphenyl sulfides as selective serotonin transporter ligands: synthesis and in vitro evaluation. Journal of Medicinal Chemistry. 45: 1253-8. PMID 11881994  0.48
2002 Kodas E, Page G, Zimmer L, Vancassel S, Guilloteau D, Durand G, Chalon S. Neither the density nor function of striatal dopamine transporters were influenced by chronic n-3 polyunsaturated fatty acid deficiency in rodents. Neuroscience Letters. 321: 95-9. PMID 11872265  0.48
2001 Vancassel S, Durand G, Barthélémy C, Lejeune B, Martineau J, Guilloteau D, Andrès C, Chalon S. Plasma fatty acid levels in autistic children Prostaglandins Leukotrienes and Essential Fatty Acids. 65: 1-7. PMID 11487301 DOI: 10.1054/plef.2001.0281  0.32
2001 Emond P, Helfenbein J, Chalon S, Garreau L, Vercouillie J, Frangin Y, Besnard JC, Guilloteau D. Synthesis of tropane and nortropane analogues with phenyl substitutions as serotonin transporter ligands. Bioorganic & Medicinal Chemistry. 9: 1849-55. PMID 11425587 DOI: 10.1016/S0968-0896(01)00083-9  0.48
2001 Diot P, Galinier E, Grimbert D, Bugeon S, Valat C, Lemarié E, Diot E, Baulieu JL, Besnard JC, Guilloteau D. Characterization of 99mTc-DTPA aerosols for lung permeability studies. Respiration; International Review of Thoracic Diseases. 68: 313-7. PMID 11416254 DOI: 10.1159/000050516  0.4
2000 Gouhier C, Chalon S, Venier-Julienne MC, Bodard S, Benoit J, Besnard J, Guilloteau D. Neuroprotection of nerve growth factor-loaded microspheres on the D2 dopaminergic receptor positive-striatal neurones in quinolinic acid-lesioned rats: a quantitative autoradiographic assessment with iodobenzamide. Neuroscience Letters. 288: 71-5. PMID 10869818 DOI: 10.1016/S0304-3940(00)01172-1  0.48
1999 Helfenbein J, Loc'h C, Bottlaender M, Emond P, Coulon C, Ottaviani M, Fuseau C, Chalon S, Guenther I, Besnard JC, Frangin Y, Guilloteau D, Maziere B. A selective radiobrominated cocaine analogue for imaging of dopamine uptake sites: pharmacological evaluation and PET experiments. Life Sciences. 65: 2715-26. PMID 10622281 DOI: 10.1016/S0024-3205(99)00540-8  0.48
1999 Helfenbein J, Sandell J, Halldin C, Chalon S, Emond P, Okubo Y, Chou YH, Frangin Y, Douziech L, Gareau L, Swahn CG, Besnard JC, Farde L, Guilloteau D. PET examination of three potent cocaine derivatives as specific radioligands for the serotonin transporter. Nuclear Medicine and Biology. 26: 491-9. PMID 10473187 DOI: 10.1016/S0969-8051(99)00004-9  0.32
1999 Baulieu JL, Ribeiro MJ, Levilion-Prunier C, Tranquart F, Chartier JR, Guilloteau D, Cottier JP, Besnard JC, Pourcelot L, Autret A. Effects of the method of drawing regions of interest on the differential diagnosis of extrapyramidal syndromes using 123I-iodolisuride SPET. Nuclear Medicine Communications. 20: 77-84. PMID 9949416 DOI: 10.1097/00006231-199901000-00012  0.4
1999 Hall H, Halldin C, Guilloteau D, Chalon S, Emond P, Besnard J, Farde L, Sedvall G. Visualization of the dopamine transporter in the human brain postmortem with the new selective ligand [125I]PE2I. Neuroimage. 9: 108-16. PMID 9918732 DOI: 10.1006/nimg.1998.0366  0.32
1998 Chalon S, Delion-Vancassel S, Belzung C, Guilloteau D, Leguisquet AM, Besnard JC, Durand G. Dietary fish oil affects monoaminergic neurotransmission and behavior in rats. The Journal of Nutrition. 128: 2512-9. PMID 9868201 DOI: 10.1093/JN/128.12.2512  0.32
1998 Emond P, Farde L, Chalon S, Belzung C, Mauclaire V, Chiron JP, Halldin C, Besnard JC, Guilloteau D. Toxicity, mutagenicity, and behavioral effects of beta-CIT, a ligand for dopamine transporter exploration by SPECT. Nuclear Medicine and Biology. 25: 405-9. PMID 9639303 DOI: 10.1016/S0969-8051(97)00227-8  0.32
1998 Kuikka JT, Baulieu JL, Hiltunen J, Halldin C, Bergström KA, Farde L, Emond P, Chalon S, Yu M, Nikula T, Laitinen T, Karhu J, Tupala E, Hallikainen T, Kolehmainen V, ... ... Guilloteau D, et al. Pharmacokinetics and dosimetry of iodine-123 labelled PE2I in humans, a radioligand for dopamine transporter imaging. European Journal of Nuclear Medicine. 25: 531-4. PMID 9575250 DOI: 10.1007/s002590050254  0.48
1998 Huguet F, Guerraoui A, Barrier L, Guilloteau D, Tallineau C, Chalon S. Changes in excitatory amino acid levels and tissue energy metabolites of neonate rat brain after hypoxia and hypoxia-ischemia. Neuroscience Letters. 240: 102-6. PMID 9486482 DOI: 10.1016/S0304-3940(97)00907-5  0.48
1995 Branger C, Garreau L, Dognon AM, Frangin Y, Caillet M, Ombetta-Goka JE, Chalon S, Besnard JC, Guilloteau D. Synthesis of 4'-iodo-5-methoxy-valerophenone O-(2-aminoethyl)oxime as an agent for exploration of serotoninergic transporter. Nuclear Medicine and Biology. 22: 157-64. PMID 7767308 DOI: 10.1016/0969-8051(94)00109-W  0.48
1992 Ribeiro-Barras MJ, Foulon C, Baulieu JL, Guilloteau D, Bougnoux P, Lansac J, Besnard JC. Estrogen receptor imaging with 17 alpha-[123I]iodovinyl-11 beta-methoxyestradiol (MIVE2)--Part II. Preliminary results in patients with breast carcinoma. International Journal of Radiation Applications and Instrumentation. Part B, Nuclear Medicine and Biology. 19: 263-7. PMID 1629015 DOI: 10.1016/0883-2897(92)90109-C  0.4
1992 Foulon C, Guilloteau D, Baulieu JL, Ribeiro-Barras MJ, Desplanches G, Frangin Y, Besnard JC. Estrogen receptor imaging with 17 alpha-[123I]iodovinyl-11 beta-methoxyestradiol (MIVE2)--Part I. Radiotracer preparation and characterization. International Journal of Radiation Applications and Instrumentation. Part B, Nuclear Medicine and Biology. 19: 257-61. PMID 1629014 DOI: 10.1016/0883-2897(92)90108-B  0.4
1992 Foulon C, Garreau L, Chalon S, Desplanches G, Frangin Y, Besnard JC, Baulieu JL, Guilloteau D. Synthesis and in vitro binding properties of halogenated analogues of GBR as new dopamine uptake carrier ligands. International Journal of Radiation Applications and Instrumentation. Part B, Nuclear Medicine and Biology. 19: 597-600. PMID 1399689 DOI: 10.1016/0883-2897(92)90155-R  0.48
1990 Chalon S, Guimbal C, Guilloteau D, Mayo W, Huguet F, Schmitt MH, Desplances G, Baulieu JL, Besnard JC. Iodobenzamide for in vivo exploration of central dopamine receptros: Evaluation in animal models of supersensitivity Life Sciences. 47: 729-734. PMID 2402193 DOI: 10.1016/0024-3205(90)90628-5  0.32
1990 Chalon S, Frangin Y, Guilloteau D, Caillet M, Guimbal C, Schmitt MH, Desplanches G, Baulieu JL, Besnard JC. Iodoethylspiperone, a new potential agent for exploration of central dopamine D2 receptors: Synthesis and preliminary in vivo study International Journal of Radiation Applications and Instrumentation.. 17. DOI: 10.1016/0883-2897(90)90106-B  0.32
1989 Narod SA, Sobol H, Nakamura Y, Calmettes C, Baulieu JL, Bigorgne JC, Chabrier G, Couette J, de Gennes JL, Duprey J, Gardet P, Guillausseau PJ, Guilloteau D, Houdent C, Lefebvre J, et al. Linkage analysis of hereditary thyroid carcinoma with and without pheochromocytoma Human Genetics. 83: 353-358. PMID 2572534 DOI: 10.1007/BF00291380  0.32
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