Michaela R. Reagan, Ph.D. - Publications

Affiliations: 
2011 Biomedical Engineering Tufts University, Boston 
Area:
Biomedical Engineering, Cell Biology, Oncology

103 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Farrell M, Fairfield H, Karam M, D'Amico A, Murphy CS, Falank C, Pistofidi RS, Cao A, Marinac CR, Dragon JA, McGuinness L, Gartner CG, Iorio RD, Jachimowicz E, DeMambro V, ... ... Reagan MR, et al. Targeting the fatty acid binding proteins disrupts multiple myeloma cell cycle progression and MYC signaling. Elife. 12. PMID 36880649 DOI: 10.7554/eLife.81184  0.311
2023 Fairfield H, Condruti R, Farrell M, Di Iorio R, Gartner CA, Vary C, Reagan MR. Development and characterization of three cell culture systems to investigate the relationship between primary bone marrow adipocytes and myeloma cells. Frontiers in Oncology. 12: 912834. PMID 36713534 DOI: 10.3389/fonc.2022.912834  0.446
2021 Lucas S, Tencerova M, von der Weid B, Andersen TL, Attané C, Behler-Janbeck F, Cawthorn WP, Ivaska KK, Naveiras O, Podgorski I, Reagan MR, van der Eerden BCJ. Guidelines for Biobanking of Bone Marrow Adipose Tissue and Related Cell Types: Report of the Biobanking Working Group of the International Bone Marrow Adiposity Society. Frontiers in Endocrinology. 12: 744527. PMID 34646237 DOI: 10.3389/fendo.2021.744527  0.329
2021 Lelis Carvalho A, Treyball A, Brooks DJ, Costa S, Neilson RJ, Reagan MR, Bouxsein ML, Motyl KJ. TRPM8 modulates temperature regulation in a sex-dependent manner without affecting cold-induced bone loss. Plos One. 16: e0231060. PMID 34086678 DOI: 10.1371/journal.pone.0231060  0.31
2021 Jafari A, Fairfield H, Andersen TL, Reagan MR. Myeloma-bone marrow adipocyte axis in tumour survival and treatment response. British Journal of Cancer. PMID 33859343 DOI: 10.1038/s41416-021-01371-4  0.378
2021 Costa S, Fairfield H, Farrell M, Murphy C, Soucy A, Vary C, Holdsworth G, Reagan MR. Sclerostin antibody increases trabecular bone and bone mechanical properties by increasing osteoblast activity damaged by whole-body irradiation in mice. Bone. 115918. PMID 33737193 DOI: 10.1016/j.bone.2021.115918  0.313
2021 Reagan MR, Fairfield H, Rosen CJ. Bone Marrow Adipocytes: A Link between Obesity and Bone Cancer. Cancers. 13. PMID 33498240 DOI: 10.3390/cancers13030364  0.364
2020 Fairfield H, Costa S, Falank C, Farrell M, Murphy CS, D'Amico A, Driscoll H, Reagan MR. Multiple Myeloma Cells Alter Adipogenesis, Increase Senescence-Related and Inflammatory Gene Transcript Expression, and Alter Metabolism in Preadipocytes. Frontiers in Oncology. 10: 584683. PMID 33680918 DOI: 10.3389/fonc.2020.584683  0.422
2020 Fairfield H, Dudakovic A, Khatib CM, Farrell M, Costa S, Falank C, Hinge M, Murphy CS, DeMambro V, Pettitt JA, Lary CW, Driscoll HE, McDonald MM, Kassem M, Rosen C, ... ... Reagan MR, et al. Myeloma-modified adipocytes exhibit metabolic dysfunction and a senescence-associated secretory phenotype (SASP). Cancer Research. PMID 33218968 DOI: 10.1158/0008-5472.CAN-20-1088  0.467
2020 Fairfield H, Costa S, DeMambro V, Schott C, Martins JDS, Ferron M, Vary C, Reagan MR. Targeting Bone Cells During Sexual Maturation Reveals Sexually Dimorphic Regulation of Endochondral Ossification. Jbmr Plus. 4: e10413. PMID 33210065 DOI: 10.1002/jbm4.10413  0.333
2020 Farrell M, Fairfield H, Costa S, D'Amico A, Falank C, Brooks DJ, Reagan MR. Sclerostin-Neutralizing Antibody Treatment Rescues Negative Effects of Rosiglitazone on Mouse Bone Parameters. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. PMID 32845528 DOI: 10.1002/Jbmr.4170  0.461
2020 Reagan MR. Critical Assessment of In Vitro and In Vivo Models to Study Marrow Adipose Tissue. Current Osteoporosis Reports. PMID 32124181 DOI: 10.1007/S11914-020-00569-4  0.416
2020 Sarkar S, Chauhan SKS, Daly J, Natoni A, Fairfield H, Henderson R, Nolan E, Swan D, Hu J, Reagan MR, O'Dwyer M. The CD38 natural killer cell line KHYG1 transiently expressing CD16 in combination with daratumumab targets multiple myeloma cells with minimal effector NK cell fratricide. Cancer Immunology, Immunotherapy : Cii. PMID 31919623 DOI: 10.1007/S00262-019-02477-8  0.384
2019 Ham J, Lever L, Fox M, Reagan MR. In Vitro 3D Cultures to Reproduce the Bone Marrow Niche. Jbmr Plus. 3: e10228. PMID 31687654 DOI: 10.1002/jbm4.10228  0.387
2019 Costa S, Reagan MR. Therapeutic Irradiation: Consequences for Bone and Bone Marrow Adipose Tissue. Frontiers in Endocrinology. 10: 587. PMID 31555210 DOI: 10.3389/Fendo.2019.00587  0.43
2019 Natoni A, Farrell ML, Harris S, Falank C, Kirkham-McCarthy L, Macauley MS, Reagan MR, O' Dwyer M. Sialyltransferase inhibition leads to inhibition of tumor cell interactions with E-selectin, VCAM1, and MADCAM1, and improves survival in a human multiple myeloma mouse model. Haematologica. PMID 31101754 DOI: 10.3324/Haematol.2018.212266  0.535
2019 Costa S, Fairfield H, Reagan MR. Inverse correlation between trabecular bone volume and bone marrow adipose tissue in rats treated with osteoanabolic agents. Bone. PMID 30954729 DOI: 10.1016/J.Bone.2019.03.038  0.431
2019 Marino S, Bishop RT, de Ridder D, Delgado-Calle J, Reagan MR. 2D and 3D In Vitro Co-Culture for Cancer and Bone Cell Interaction Studies. Methods in Molecular Biology (Clifton, N.J.). 1914: 71-98. PMID 30729461 DOI: 10.1007/978-1-4939-8997-3_5  0.444
2019 Farrell M, Falank C, Campbell HF, Costa S, Bowers D, Reagan M. Targeting bone marrow adipose tissue and the FABP family increases efficacy of dexamethasone in MM Clinical Lymphoma Myeloma and Leukemia. 19: e89-e90. DOI: 10.1016/J.Clml.2019.09.145  0.418
2019 Campbell HF, Farrell M, Falank C, Dudakovic A, Costa S, DeMambro V, Pettitt J, van Wijnen AJ, McDonald M, Reagan M. A New ‘Vicious Cycle’: Bidirectional Interactions Between Myeloma Cells and Adipocytes Clinical Lymphoma Myeloma and Leukemia. 19: e88-e89. DOI: 10.1016/J.Clml.2019.09.143  0.331
2018 Harmer D, Falank C, Reagan MR. Interleukin-6 Interweaves the Bone Marrow Microenvironment, Bone Loss, and Multiple Myeloma. Frontiers in Endocrinology. 9: 788. PMID 30671025 DOI: 10.3389/Fendo.2018.00788  0.42
2018 Tsukamoto S, Løvendorf MB, Park J, Salem KZ, Reagan MR, Manier S, Zavidij O, Rahmat M, Huynh D, Takagi S, Kawano Y, Kokubun K, Thrue CA, Nagano K, Petri A, et al. Inhibition of microRNA-138 enhances bone formation in multiple myeloma bone marrow niche. Leukemia. PMID 29925904 DOI: 10.1038/S41375-018-0161-6  0.441
2018 Farrell ML, Reagan MR. Soluble and Cell-Cell-Mediated Drivers of Proteasome Inhibitor Resistance in Multiple Myeloma. Frontiers in Endocrinology. 9: 218. PMID 29765356 DOI: 10.3389/Fendo.2018.00218  0.402
2018 Sitarski AM, Fairfield H, Falank C, Reagan MR. 3d Tissue Engineered In Vitro Models Of Cancer In Bone. Acs Biomaterials Science & Engineering. 4: 324-336. PMID 29756030 DOI: 10.1021/Acsbiomaterials.7B00097  0.442
2018 Fairfield H, Falank C, Farrell M, Vary C, Boucher JM, Driscoll H, Liaw L, Rosen CJ, Reagan MR. Development of a 3D bone marrow adipose tissue model. Bone. PMID 29366838 DOI: 10.1016/J.Bone.2018.01.023  0.481
2018 Natoni A, Farrell M, Fairfield H, Kirkham-McCarthy L, Macauley M, Reagan M, O'Dwyer ME. Inhibition of Sialylation Impairs Adhesion on Madcam-1 and E-Selectin and Sensitize Multiple Myeloma Cells to Bortezomib in a Xenograft Mouse Model Blood. 132: 3204-3204. DOI: 10.1182/Blood-2018-99-118361  0.476
2018 Fischbach C, Reagan M. Editorial: Special Issue on Tissue Engineering and Biomaterials Approaches to Tumor Modeling Acs Biomaterials Science & Engineering. 4: 291-293. DOI: 10.1021/Acsbiomaterials.8B00085  0.311
2017 Falank C, Fairfield H, Reagan MR. Reflections on Cancer in the Bone Marrow: Adverse Roles of Adipocytes. Current Molecular Biology Reports. 3: 254-262. PMID 29399440 DOI: 10.1007/s40610-017-0074-6  0.303
2017 Bornstein S, Moschetta M, Kawano Y, Sacco A, Huynh D, Brooks D, Manier S, Fairfield H, Falank C, Roccaro AM, Nagano K, Baron R, Bouxein M, Vary C, Ghobrial IM, ... ... Reagan MR, et al. Metformin Affects Cortical Bone Mass and Marrow Adiposity in Diet-Induced Obesity in Male Mice. Endocrinology. 158: 3369-3385. PMID 28977604 DOI: 10.1210/En.2017-00299  0.377
2017 Moschetta M, Kawano Y, Sacco A, Belotti A, Ribolla R, Chiarini M, Giustini V, Bertoli D, Sottini A, Valotti M, Ghidini C, Serana F, Malagola M, Imberti L, Russo D, ... ... Reagan MR, et al. Bone Marrow Stroma and Vascular Contributions to Myeloma Bone Homing. Current Osteoporosis Reports. PMID 28889371 DOI: 10.1007/S11914-017-0399-3  0.477
2017 Fairfield H, Rosen CJ, Reagan MR. Connecting Bone and Fat: The Potential Role for Sclerostin. Current Molecular Biology Reports. 3: 114-121. PMID 28580233 DOI: 10.1007/s40610-017-0057-7  0.313
2017 Liu P, Ji Y, Yuen T, Rendina-Ruedy E, DeMambro VE, Dhawan S, Abu-Amer W, Izadmehr S, Zhou B, Shin AC, Latif R, Thangeswaran P, Gupta A, Li J, Shnayder V, ... ... Reagan MR, et al. Blocking FSH induces thermogenic adipose tissue and reduces body fat. Nature. PMID 28538730 DOI: 10.1097/01.Ogx.0000525900.85600.C2  0.334
2017 McDonald MM, Reagan MR, Youlten SE, Mohanty ST, Seckinger A, Terry RL, Pettitt JA, Simic MK, Cheng TL, Morse A, Le LMT, Abi-Hanna D, Kramer I, Falank C, Fairfield H, et al. Inhibiting the osteocyte specific protein sclerostin increases bone mass and fracture resistance in multiple myeloma. Blood. PMID 28515094 DOI: 10.1182/Blood-2017-03-773341  0.439
2017 Sacco A, Kawano Y, Moschetta M, Zavidij O, Huynh D, Reagan M, Mishima Y, Manier S, Park J, Morgan E, Takagi S, Wong KK, Carrasco R, Ghobrial IM, Roccaro AM. A novel in vivo model for studying conditional dual loss of BLIMP-1 and p53 in B-cells, leading to tumor transformation. American Journal of Hematology. PMID 28474779 DOI: 10.1002/Ajh.24778  0.378
2017 Fairfield H, Falank C, Harris E, Demambro V, McDonald M, Pettit JA, Mohanty ST, Croucher P, Kramer I, Kneissel M, Rosen CJ, Reagan MR. The Skeletal Cell-Derived Molecule Sclerostin Drives Bone Marrow Adipogenesis. Journal of Cellular Physiology. PMID 28460416 DOI: 10.1002/Jcp.25976  0.481
2017 Soley L, Falank C, Reagan MR. MicroRNA Transfer Between Bone Marrow Adipose and Multiple Myeloma Cells. Current Osteoporosis Reports. PMID 28432594 DOI: 10.1007/S11914-017-0360-5  0.495
2017 Glavey SV, Naba A, Manier S, Clauser K, Tahri S, Park J, Reagan MR, Moschetta M, Mishima Y, Gambella M, Rocci A, Sacco A, O'Dwyer ME, Asara JM, Palumbo A, et al. Proteomic characterization of human multiple myeloma bone marrow extracellular matrix. Leukemia. PMID 28344315 DOI: 10.1038/Leu.2017.102  0.494
2017 Reagan MR, Lian J, Rosen CJ, Stein G. A Perspective on Malignancy in the Marrow. Journal of Cellular Physiology. PMID 28206683 DOI: 10.1002/Jcp.25860  0.474
2017 Bar-Natan M, Stroopinsky D, Luptakova K, Coll MD, Apel A, Rajabi H, Pyzer AR, Palmer K, Reagan MR, Nahas MR, Karp Leaf R, Jain S, Arnason J, Ghobrial IM, Anderson KC, et al. Bone marrow stroma protects myeloma cells from cytotoxic damage via induction of the oncoprotein MUC1. British Journal of Haematology. PMID 28107546 DOI: 10.1111/Bjh.14493  0.448
2017 Falank C, Fairfield H, Farrell M, Reagan M. New Bone Cell Type Identified as Driver of Drug Resistance in Multiple Myeloma: The Bone Marrow Adipocyte Blood. 130: 122-122. DOI: 10.1182/Blood.V130.Suppl_1.122.122  0.538
2016 Dadwal U, Falank C, Fairfield H, Linehan S, Rosen CJ, Kaplan DL, Sterling J, Reagan MR. Tissue-engineered 3D cancer-in-bone modeling: silk and PUR protocols. Bonekey Reports. 5: 842. PMID 27790370 DOI: 10.1038/Bonekey.2016.75  0.557
2016 Manier S, Powers JT, Sacco A, Glavey SV, Huynh D, Reagan MR, Salem KZ, Moschetta M, Shi J, Mishima Y, Roche-Lestienne C, Leleu X, Roccaro AM, Daley GQ, Ghobrial IM. The LIN28B/let-7 axis is a novel therapeutic pathway in multiple myeloma. Leukemia. PMID 27773931 DOI: 10.1038/Leu.2016.296  0.43
2016 Falank C, Fairfield H, Reagan MR. Signaling Interplay between Bone Marrow Adipose Tissue and Multiple Myeloma cells. Frontiers in Endocrinology. 7: 67. PMID 27379019 DOI: 10.3389/Fendo.2016.00067  0.521
2016 McDonald MM, Fairfield H, Falank C, Reagan MR. Adipose, Bone, and Myeloma: Contributions from the Microenvironment. Calcified Tissue International. PMID 27343063 DOI: 10.1007/S00223-016-0162-2  0.522
2016 Abbott RD, Wang RY, Reagan MR, Chen Y, Borowsky FE, Zieba A, Marra KG, Rubin JP, Ghobrial IM, Kaplan DL. The Use of Silk as a Scaffold for Mature, Sustainable Unilocular Adipose 3D Tissue Engineered Systems. Advanced Healthcare Materials. PMID 27197588 DOI: 10.1002/Adhm.201600211  0.429
2016 Fairfield H, Falank C, Avery L, Reagan MR. Multiple myeloma in the marrow: pathogenesis and treatments. Annals of the New York Academy of Sciences. 1364: 32-51. PMID 27002787 DOI: 10.1111/Nyas.13038  0.49
2016 Moschetta M, Mishima Y, Kawano Y, Manier S, Paiva B, Palomera L, Aljawai Y, Calcinotto A, Unitt C, Sahin I, Sacco A, Glavey S, Shi J, Reagan MR, Prosper F, et al. Targeting vasculogenesis to prevent progression in multiple myeloma. Leukemia. PMID 26859080 DOI: 10.1038/Leu.2016.3  0.462
2016 McDonald M, Reagan M, Terry R, Pettitt J, Le L, Mohanty S, Kramer I, Kneissel M, Brooks D, Cheng T, Little D, Bouxsein M, Rosen C, Ghobrial I, Croucher P. Anti-sclerostin treatment prevents multiple myeloma bone disease and reduces tumour burden Bone Abstracts. DOI: 10.1530/Boneabs.5.Cabs.Oc3.4  0.385
2016 Tsukamoto S, Salem K, Manier S, Reagan MR, Huynh D, Perilla-Glen A, Sacco A, Zavidij O, Rahmat M, Takagi S, Kawano Y, Kokubun K, Thrue CA, Petri A, Dorfman DM, et al. Microrna-138 Regulates Osteogenic Differentiation and Its Inhibition Presents a Novel Therapeutic Line to Prevent Bone Lytic Lesions in Multiple Myeloma Blood. 128: 4483-4483. DOI: 10.1182/Blood.V128.22.4483.4483  0.412
2016 Sacco A, Kawano Y, Moschetta M, Park J, Zavidij O, Reagan M, Mishima Y, Morgan EA, Takagi S, Manier S, Imberti L, Rossi G, Wong K, Carrasco RD, Ghobrial IM, et al. Dual Conditional Loss of BLIMP-1 and p53 in B-Cells Drives B-Cell Lymphomagenesis Blood. 128: 4169-4169. DOI: 10.1182/Blood.V128.22.4169.4169  0.359
2016 Reagan M, Falank C, Fairfield H, McDonald M, Croucher P, Rosen CJ. Multiple Myeloma Progression: Dependence on Bone Marrow Adipose Tissue Blood. 128: 3262-3262. DOI: 10.1182/Blood.V128.22.3262.3262  0.499
2015 Reagan MR, Rosen CJ. Navigating the bone marrow niche: translational insights and cancer-driven dysfunction. Nature Reviews. Rheumatology. PMID 26607387 DOI: 10.1038/Nrrheum.2015.160  0.477
2015 Roccaro AM, Mishima Y, Sacco A, Moschetta M, Tai YT, Shi J, Zhang Y, Reagan MR, Huynh D, Kawano Y, Sahin I, Chiarini M, Manier S, Cea M, Aljawai Y, et al. CXCR4 Regulates Extra-Medullary Myeloma through Epithelial-Mesenchymal-Transition-like Transcriptional Activation. Cell Reports. 12: 622-35. PMID 26190113 DOI: 10.1016/J.Celrep.2015.06.059  0.503
2015 Reagan MR, Liaw L, Rosen CJ, Ghobrial IM. Dynamic interplay between bone and multiple myeloma: emerging roles of the osteoblast. Bone. 75: 161-9. PMID 25725265 DOI: 10.1016/J.Bone.2015.02.021  0.486
2015 Glavey SV, Huynh D, Reagan MR, Manier S, Moschetta M, Kawano Y, Roccaro AM, Ghobrial IM, Joshi L, O'Dwyer ME. The cancer glycome: carbohydrates as mediators of metastasis. Blood Reviews. 29: 269-79. PMID 25636501 DOI: 10.1016/J.Blre.2015.01.003  0.409
2015 Kawano Y, Moschetta M, Kokubun K, Lukyanchykov P, Sula Karreci E, Manier S, Tsukamoto S, Takagi S, Shi J, Reagan MR, Huynh D, Sacco A, Dorfman DM, Chesi M, Bergsagel PL, et al. Characterization of the Role of Regulatory T Cells (Tregs) in Inducing Progression of Multiple Myeloma Blood. 126: 502-502. DOI: 10.1182/Blood.V126.23.502.502  0.417
2015 Manier S, Powers J, Sacco A, Glavey S, Huynh D, Reagan MR, Salem K, Moschetta M, Mishima Y, Leleu X, Roccaro AM, Daley GQ, Ghobrial IM. MYC Regulation Via the LIN28B/Let-7 Axis in Multiple Myeloma Blood. 126: 1755-1755. DOI: 10.1182/Blood.V126.23.1755.1755  0.44
2015 Reagan MR, McDonald M, Terry R, Pettitt J, Le L, Mohanty S, Kneissel M, Kramer I, Brooks D, Bouxsein M, Rosen CJ, Ghobrial IM, Croucher P. Anti-Sclerostin Treatment Prevents Multiple Myeloma Induced Bone Loss and Reduces Tumor Burden Blood. 126: 119-119. DOI: 10.1182/Blood.V126.23.119.119  0.501
2015 Roccaro AM, Sacco A, Maiso P, Moschetta M, Manier S, Mishima Y, Reagan M, Aljawai Y, Ghobrial IM. Abstract B62: Stroma-derived exosomes mediate progression in multiple meyloma Cancer Research. 75. DOI: 10.1158/1538-7445.Chtme14-B62  0.445
2014 Zhang W, Wang YE, Zhang Y, Leleu X, Reagan M, Zhang Y, Mishima Y, Glavey S, Manier S, Sacco A, Jiang B, Roccaro AM, Ghobrial IM. Global epigenetic regulation of microRNAs in multiple myeloma. Plos One. 9: e110973. PMID 25330074 DOI: 10.1371/Journal.Pone.0110973  0.352
2014 Roccaro AM, Sacco A, Purschke WG, Moschetta M, Buchner K, Maasch C, Zboralski D, Zöllner S, Vonhoff S, Mishima Y, Maiso P, Reagan MR, Lonardi S, Ungari M, Facchetti F, et al. SDF-1 inhibition targets the bone marrow niche for cancer therapy. Cell Reports. 9: 118-28. PMID 25263552 DOI: 10.1016/J.Celrep.2014.08.042  0.537
2014 Zhang Y, Moschetta M, Huynh D, Tai YT, Zhang Y, Zhang W, Mishima Y, Ring JE, Tam WF, Xu Q, Maiso P, Reagan M, Sahin I, Sacco A, Manier S, et al. Pyk2 promotes tumor progression in multiple myeloma. Blood. 124: 2675-86. PMID 25217697 DOI: 10.1182/Blood-2014-03-563981  0.432
2014 Reagan MR, Mishima Y, Glavey SV, Zhang Y, Manier S, Lu ZN, Memarzadeh M, Zhang Y, Sacco A, Aljawai Y, Shi J, Tai YT, Ready JE, Kaplan DL, Roccaro AM, et al. Investigating osteogenic differentiation in multiple myeloma using a novel 3D bone marrow niche model. Blood. 124: 3250-9. PMID 25205118 DOI: 10.1182/Blood-2014-02-558007  0.577
2014 Glavey SV, Manier S, Natoni A, Sacco A, Moschetta M, Reagan MR, Murillo LS, Sahin I, Wu P, Mishima Y, Zhang Y, Zhang W, Zhang Y, Morgan G, Joshi L, et al. The sialyltransferase ST3GAL6 influences homing and survival in multiple myeloma. Blood. 124: 1765-76. PMID 25061176 DOI: 10.1182/Blood-2014-03-560862  0.498
2014 Swami A, Reagan MR, Basto P, Mishima Y, Kamaly N, Glavey S, Zhang S, Moschetta M, Seevaratnam D, Zhang Y, Liu J, Memarzadeh M, Wu J, Manier S, Shi J, et al. Engineered nanomedicine for myeloma and bone microenvironment targeting. Proceedings of the National Academy of Sciences of the United States of America. 111: 10287-92. PMID 24982170 DOI: 10.1073/Pnas.1401337111  0.391
2014 Tai YT, Landesman Y, Acharya C, Calle Y, Zhong MY, Cea M, Tannenbaum D, Cagnetta A, Reagan M, Munshi AA, Senapedis W, Saint-Martin JR, Kashyap T, Shacham S, Kauffman M, et al. CRM1 inhibition induces tumor cell cytotoxicity and impairs osteoclastogenesis in multiple myeloma: molecular mechanisms and therapeutic implications. Leukemia. 28: 155-65. PMID 23588715 DOI: 10.1038/Leu.2013.115  0.524
2014 Moschetta M, Mishima Y, Kawano Y, Aljawai Y, Paiva B, Palomera L, Calcinotto A, Christine UL, Sahin I, Sacco A, Glavey S, Reagan MR, Manier S, Bergsagel PL, Chesi M, et al. Early Trafficking of Bone Marrow Derived-Endothelial Progenitor Cells Promotes Multiple Myeloma Progression Blood. 124: 4719-4719. DOI: 10.1182/Blood.V124.21.4719.4719  0.439
2014 Glavey S, Reagan M, Manier S, Moschetta M, Kawano Y, Sacco A, Roccaro AM, Robbins M, Ghobrial IM. Dissecting the Mechanisms of Activity of SLAMF7 and the Targeting Antibody Elotuzumab in Multiple Myeloma Blood. 124: 3431-3431. DOI: 10.1182/Blood.V124.21.3431.3431  0.457
2014 Mishima Y, Moschetta M, Shi J, Mercier F, Manier S, Glavey S, Reagan MR, Kawano Y, Munshi NC, Anderson KC, Roccaro AM, Hide W, Scadden DT, Ghobrial IM. Clonal-Heterogeneity and Propensity for Bone Metastasis in Multiple Myeloma Blood. 124: 3370-3370. DOI: 10.1182/Blood.V124.21.3370.3370  0.472
2014 Zhang Y, Zhang Y, Mishima Y, Moschetta M, Zhang W, Maiso P, Sacco A, Aljawai Y, Sahin I, Reagan MR, Ring JE, Tam WF, Xu Q, Pachter JA, Roccaro AM, et al. Proline-Rich Tyrosine Kinase (Pyk2) Promotes Tumor Progression in Multiple Myeloma (MM) and Represents a Novel Target for Therapy in MM Blood. 124: 2101-2101. DOI: 10.1182/Blood.V124.21.2101.2101  0.484
2014 Manier S, Avet-Loiseau H, Campigotto F, Glavey S, Salem K, Huynh D, Boswell EN, Sacco A, Mishima Y, Moschetta M, Reagan MR, Kawano Y, Anderson KC, Roccaro AM, Moreau P, et al. Prognostic Value of Circulating Exosomal microRNAs in 112 Patients with Multiple Myeloma Blood. 124: 2056-2056. DOI: 10.1182/Blood.V124.21.2056.2056  0.316
2014 Glavey S, Naba A, Manier S, Gambella M, Rocci A, Sacco A, Asara JM, Moschetta M, Reagan MR, Mishima Y, Kawano Y, Roccaro AM, Palumbo A, Hynes RO, Ghobrial IM. Proteomic Characterization of the Multiple Myeloma Bone Marrow Extracellular Matrix Blood. 124: 2051-2051. DOI: 10.1182/Blood.V124.21.2051.2051  0.493
2014 O'Callaghan G, Reagan MR, Flores L, Zhang Y, Azab A, Roccaro A, Shanahan F, Ghobrial I, Houston A. Tu1677 Upregulation of Fas Ligand Expression Promotes Colon Cancer Cell Migration and Metastasis In Vitro and In Vivo Gastroenterology. 146: S-816. DOI: 10.1016/S0016-5085(14)62953-X  0.392
2013 Roccaro AM, Sacco A, Maiso P, Azab AK, Tai YT, Reagan M, Azab F, Flores LM, Campigotto F, Weller E, Anderson KC, Scadden DT, Ghobrial IM. BM mesenchymal stromal cell-derived exosomes facilitate multiple myeloma progression. The Journal of Clinical Investigation. 123: 1542-55. PMID 23454749 DOI: 10.1172/Jci66517  0.492
2013 Reagan MR, Swami A, Basto PA, Mishima Y, Liu J, Glavey S, O'Callaghan GB, Moschetta M, Nagano K, Baron R, Roccaro AM, Farokhzad O, Ghobrial IM. Nanoparticle Design For Bone-Specific Chemotherapy and Microenvironmental Targeting In Multiple Myeloma Blood. 122: 881-881. DOI: 10.1182/Blood.V122.21.881.881  0.479
2013 Mishima Y, Moschetta M, Reagan MR, Zhang Y, Sahin I, Maulkhan N, Roccaro AM, Ghobrial IM. CXCR4 Is a Regulator Of Disease Involvement Of Extramedullary Myeloma Confirmed By a Novel Mouse Model For Extramedullary Disease Blood. 122: 5320-5320. DOI: 10.1182/Blood.V122.21.5320.5320  0.454
2013 Zhang W, Zhang Y, Zhang Y, Mishima Y, Reagan M, Glavey S, Sacco A, Roccaro AM, Ghobrial IM. Methylation-Dependent Epigenetic Silencing Of Mir-152 and Mir-10b-5p Plays a Crucial Role In Modulating Tumor Progression In Multiple Myeloma Blood. 122: 3751-3751. DOI: 10.1182/Blood.V122.21.3751.3751  0.311
2013 Zhang Y, Zhang Y, Mishima Y, Moschetta M, Zhang W, Maiso P, Sacco A, Aljawai Y, Sahin I, Reagan M, Roccaro AM, Ghobrial IM. Proline-Rich Tyrosine Kinase (Pyk2) Promotes Tumor Progression In Multiple Myeloma Through Modulation Of Wnt/β-Catenin Signaling Pathway Blood. 122: 3094-3094. DOI: 10.1182/Blood.V122.21.3094.3094  0.461
2013 Manier S, Boswell EN, Glavey S, Sacco A, Maiso P, Mishima Y, Aljaway Y, Banwait R, Zhang W, Zhang Y, Sahin I, Moschetta M, Zhang Y, Reagan MR, Asara JM, et al. Mirna Expression Profiling and Proteomic Analysis Of Circulating Exosomes From Multiple Myeloma Patients Blood. 122: 3086-3086. DOI: 10.1182/Blood.V122.21.3086.3086  0.39
2013 Glavey S, Manier S, Sacco A, Reagan MR, Mishima Y, Zhang Y, Sahin I, Zhang Y, Zhang W, Murillo LS, Loughrey C, Natoni A, Kazlowska K, Joshi L, Roccaro AM, et al. Silencing The Sialyltransferase Gene ST3GAL6 Inhibits Adhesion and Migration Of Myeloma Cells In Vitro and Reduces The Homing and Proliferation Of Tumor Cells In Vivo Blood. 122: 275-275. DOI: 10.1182/Blood.V122.21.275.275  0.516
2013 Manier S, Powers JT, Sacco A, Reagan MR, Moschetta M, Glavey S, Maiso P, Sahin I, Mishima Y, Aljaway Y, Leleu X, Roccaro AM, Daley GQ, Ghobrial IM. Lin28B/Let-7 Axis Regulates Multiple Myeloma Proliferation By Enhancing c-Myc and Ras Survival Pathways Blood. 122: 273-273. DOI: 10.1182/Blood.V122.21.273.273  0.463
2013 Tai Y, Landesman Y, Acharya C, Calle Y, Zhong M, Cea M, Tannenbaum D, Cagnetta A, Reagan M, Munshi A, Senapedis W, Saint-Martin J, Kashyap T, Shacham S, Kauffman M, et al. Abstract 2142: The nuclear export protein CRM1 (XPO1) regulates multiple myeloma cell growth, osteoclastogenesis, and myeloma-induced osteolysis. Cancer Research. 73: 2142-2142. DOI: 10.1158/1538-7445.Am2013-2142  0.486
2013 O'Callaghan GP, Reagan M, Flores LM, Zhang Y, Roccaro A, Shanahan F, Ghobrial I, Houston A. Sa1681 Inhibition of the Prostaglandin EP1 Receptor Suppresses Colon Cancer Cell Invasion and Metastasis. Gastroenterology. 144: S-281. DOI: 10.1016/S0016-5085(13)60994-4  0.337
2012 Reagan MR, Seib FP, McMillin DW, Sage EK, Mitsiades CS, Janes SM, Ghobrial IM, Kaplan DL. Stem Cell Implants for Cancer Therapy: TRAIL-Expressing Mesenchymal Stem Cells Target Cancer Cells In Situ. Journal of Breast Cancer. 15: 273-82. PMID 23091539 DOI: 10.4048/Jbc.2012.15.3.273  0.51
2012 Zhang Y, Roccaro AM, Rombaoa C, Flores L, Obad S, Fernandes SM, Sacco A, Liu Y, Ngo H, Quang P, Azab AK, Azab F, Maiso P, Reagan M, Brown JR, et al. LNA-mediated anti-miR-155 silencing in low-grade B-cell lymphomas. Blood. 120: 1678-86. PMID 22797699 DOI: 10.1182/Blood-2012-02-410647  0.34
2012 Reagan MR, Ghobrial IM. Multiple myeloma mesenchymal stem cells: characterization, origin, and tumor-promoting effects. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 18: 342-9. PMID 22065077 DOI: 10.1158/1078-0432.Ccr-11-2212  0.509
2012 Reagan MR, Philipp Seib F, McMillin DW, Sage EK, Mitsiades CS, Janes SM, Ghobrial IM, Kaplan DL. Stem cell implants for cancer therapy: TRAIL-expressing mesenchymal stem cells target cancer cells in situ Journal of Breast Cancer. 15: 273-282. DOI: 10.4048/jbc.2012.15.3.273  0.391
2012 Roccaro AM, Sacco A, Kuhne MR, Azab AK, Maiso P, Azab F, Manier S, Aljaway Y, Reagan MR, Cohen L, Cardarelli PM, Ghobrial IM. CXCR4 Monoclonal Antibody, BMS-936564 (MDX-1338), Modulates Epithelial to Mesenchymal Transition (EMT) in Multiple Myeloma Cells Blood. 120: 4009-4009. DOI: 10.1182/Blood.V120.21.4009.4009  0.536
2012 Reagan MR, Roccaro AM, Azab A, Zhang Y, O'Callaghan GB, Maiso P, Manier S, Kaplan DL, Ghobrial IM. Multiple Myeloma-Derived Bone-Marrow Mesenchymal Stem Cells: Microrna-, Gene Expression-Profiling and Functional Characterization Blood. 120: 1837-1837. DOI: 10.1182/Blood.V120.21.1837.1837  0.57
2012 Acharya C, Zhong MY, Calle Y, Schey S, Chen M, Tannenbaum D, Reagan MR, Ghobrial IM, Landesman Y, Shacham S, Kauffman M, Anderson KC, Tai Y. CRM1 Inhibition Abrogates Osteoclast Formation and Bone Resorption Via Inhibition of RANKL-Induced NFκB While Sparing Osteoblastogenesis: Further Therapeutic Implication in Multiple Myeloma Blood. 120: 1835-1835. DOI: 10.1182/Blood.V120.21.1835.1835  0.498
2011 Numata K, Reagan MR, Goldstein RH, Rosenblatt M, Kaplan DL. Spider silk-based gene carriers for tumor cell-specific delivery. Bioconjugate Chemistry. 22: 1605-10. PMID 21739966 DOI: 10.1021/Bc200170U  0.493
2011 Reagan MR, Kaplan DL. Concise review: Mesenchymal stem cell tumor-homing: detection methods in disease model systems. Stem Cells (Dayton, Ohio). 29: 920-7. PMID 21557390 DOI: 10.1002/Stem.645  0.465
2011 Roccaro AM, Sacco A, Azab AK, Tai Y, Maiso P, Zhang Y, Liu Y, Reagan M, Azab F, Issa GC, Ngo HT, Quang P, Anderson KC, Dalla-Favera R, Ghobrial IM. Stroma-Derived Exosomes Mediate Oncogenesis in Multiple Myeloma Blood. 118: 625-625. DOI: 10.1182/Blood.V118.21.625.625  0.466
2011 Azab AK, Azab F, Quang P, Maiso P, Ngo HT, Zimmermann J, Patel K, Romagnoli B, Sacco A, Liu Y, Zhang Y, Reagan M, Roccaro AM, Ghobrial IM. Dissecting the role of CXCR7 in Cell Trafficking of Endothelial-Cells and Endothelial-Progenitor-Cells in Multiple Myeloma, Blood. 118: 3934-3934. DOI: 10.1182/Blood.V118.21.3934.3934  0.447
2011 Liu Y, Zhang Y, Quang P, Ngo HT, Azab F, Azab AK, Morgan B, Maiso P, Reagan M, Rombaoa CP, Sacco A, Roccaro AM, Carrasco R, Ghobrial IM. Deregulation of TNFRSF18 (GITR) Through Promoter CpG Island Methylation Induces Tumor Proliferation in Multiple Myeloma Blood. 118: 2424-2424. DOI: 10.1182/Blood.V118.21.2424.2424  0.477
2011 Maiso P, Liu Y, Azab AK, Morgan B, Azab F, Sacco A, Reagan M, Ngo HT, Liu Y, Zhang Y, Lin C, Roccaro AM, Rommel C, Ghobrial IM. Role of TORC1 and TORC2 in Multiple Myeloma Blood. 118: 1815-1815. DOI: 10.1182/Blood.V118.21.1815.1815  0.503
2011 Azab F, Azab AK, Maiso P, Quang P, Ngo HT, Sacco A, Liu Y, Zhang Y, Reagan M, Roccaro AM, Ghobrial IM. The Role of PI3K Signaling in Cell Trafficking of Multiple Myeloma Blood. 118: 1804-1804. DOI: 10.1182/Blood.V118.21.1804.1804  0.445
2011 Reagan* M, Goldstein R, Rosenblatt M, Kaplan D. Human bone marrow-derived mesenchymal stem cell homing to orthotopic breast cancer tumors and promotion of bone metastasis Bone. 48: S13. DOI: 10.1016/J.Bone.2010.10.034  0.553
2010 Sun L, Reagan MR, Kaplan DL. Role of Cartilage Forming Cells in Regenerative Medicine for Cartilage Repair. Orthopedic Research and Reviews. 2010: 85-94. PMID 24049462 DOI: 10.2147/ORR.S7194  0.37
2010 Goldstein RH, Reagan MR, Anderson K, Kaplan DL, Rosenblatt M. Human bone marrow-derived mscs can home to orthotopic breast cancer tumors and promote bone metastasis Cancer Research. 70: 10044-10050. PMID 21159629 DOI: 10.1158/0008-5472.Can-10-1254  0.536
2010 Wang X, Reagan MR, Kaplan DL. Synthetic adipose tissue models for studying mammary gland development and breast tissue engineering. Journal of Mammary Gland Biology and Neoplasia. 15: 365-76. PMID 20835885 DOI: 10.1007/S10911-010-9192-Y  0.394
2009 Zhang X, Reagan MR, Kaplan DL. Electrospun silk biomaterial scaffolds for regenerative medicine. Advanced Drug Delivery Reviews. 61: 988-1006. PMID 19643154 DOI: 10.1016/J.Addr.2009.07.005  0.396
2008 Reagan M, Faverman L, Goldstein R, Rosenblatt M, Kaplan D. P10. Disease modeling and tissue engineering: Breast cancer metastasis to bone Cancer Treatment Reviews. 34: 16. DOI: 10.1016/J.Ctrv.2008.03.051  0.475
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