Stuart M. Cain - Publications

Michael Smith Laboratories University of British Columbia, Vancouver, Vancouver, BC, Canada 

24 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Marks WN, Zabder NK, Greba Q, Cain SM, Snutch TP, Howland JG. The T-type calcium channel blocker Z944 reduces conditioned fear in Genetic Absence Epilepsy Rats from Strasbourg and the Non-Epileptic Control strain. The European Journal of Neuroscience. PMID 30889299 DOI: 10.1111/ejn.14406  0.96
2019 Loonen ICM, Jansen NA, Cain SM, Schenke M, Voskuyl RA, Yung AC, Bohnet B, Kozlowski P, Thijs RD, Ferrari MD, Snutch TP, van den Maagdenberg AMJM, Tolner EA. Brainstem spreading depolarization and cortical dynamics during fatal seizures in Cacna1a S218L mice. Brain : a Journal of Neurology. PMID 30649209 DOI: 10.1093/brain/awy325  0.96
2018 Marks WN, Zabder NK, Cain SM, Snutch TP, Howland JG. The T-type calcium channel antagonist, Z944, alters social behavior in Genetic Absence Epilepsy Rats from Strasbourg. Behavioural Brain Research. 361: 54-64. PMID 30550952 DOI: 10.1016/j.bbr.2018.12.021  0.96
2018 Cain SM, Tyson JR, Choi HB, Ko R, Lin PJC, LeDue JM, Powell KL, Bernier LP, Rungta RL, Yang Y, Cullis PR, O'Brien TJ, MacVicar BA, Snutch TP. Ca3.2 drives sustained burst-firing, which is critical for absence seizure propagation in reticular thalamic neurons. Epilepsia. PMID 29468672 DOI: 10.1111/epi.14018  0.96
2017 Proft J, Rzhepetskyy Y, Lazniewska J, Zhang FX, Cain SM, Snutch TP, Zamponi GW, Weiss N. The Cacna1h mutation in the GAERS model of absence epilepsy enhances T-type Ca(2+) currents by altering calnexin-dependent trafficking of Cav3.2 channels. Scientific Reports. 7: 11513. PMID 28912545 DOI: 10.1038/s41598-017-11591-5  0.96
2017 Cain SM, Garcia E, Waheed Z, Jones KL, Bushell TJ, Snutch TP. GABAB Receptors Suppress Burst-Firing in Reticular Thalamic Neurons. Channels (Austin, Tex.). 0. PMID 28742985 DOI: 10.1080/19336950.2017.1358836  0.96
2017 Henbid MT, Marks WN, Collins MJ, Cain SM, Snutch TP, Howland JG. Sociability impairments in Genetic Absence Epilepsy Rats from Strasbourg: Reversal by the T-type calcium channel antagonist Z944. Experimental Neurology. PMID 28658605 DOI: 10.1016/j.expneurol.2017.06.022  0.96
2017 Cain SM, Bohnet B, LeDue J, Yung AC, Garcia E, Tyson JR, Alles SR, Han H, van den Maagdenberg AM, Kozlowski P, MacVicar BA, Snutch TP. In vivo imaging reveals that pregabalin inhibits cortical spreading depression and propagation to subcortical brain structures. Proceedings of the National Academy of Sciences of the United States of America. PMID 28223480 DOI: 10.1073/pnas.1614447114  0.96
2016 Cain SM, Ahn S, Garcia E, Zhang Y, Waheed Z, Tyson JR, Yang Y, Van Sung T, Phillips AG, Snutch TP. Heantos-4, a natural plant extract used in the treatment of drug addiction, modulates T-type calcium channels and thalamocortical burst-firing. Molecular Brain. 9: 94. PMID 27919294 DOI: 10.1186/s13041-016-0274-7  0.96
2016 Marks WN, Greba Q, Cain SM, Snutch TP, Howland JG. The T-type calcium channel antagonist Z944 disrupts prepulse inhibition in both epileptic and non-epileptic rats. Neuroscience. PMID 27365170 DOI: 10.1016/j.neuroscience.2016.06.035  0.96
2016 Marks WN, Cain SM, Snutch TP, Howland JG. The T-type calcium channel antagonist Z944 rescues impairments in crossmodal and visual recognition memory in Genetic Absence Epilepsy Rats from Strasbourg. Neurobiology of Disease. PMID 27282256 DOI: 10.1016/j.nbd.2016.06.001  0.96
2015 Marks WN, Cavanagh ME, Greba Q, Cain SM, Snutch TP, Howland JG. The GAERS model of absence epilepsy exhibits alterations in fear conditioning and latent inhibition consistent with psychiatric comorbidities in humans. The European Journal of Neuroscience. PMID 26490879 DOI: 10.1111/ejn.13110  0.96
2015 Rungta RL, Choi HB, Tyson JR, Malik A, Dissing-Olesen L, Lin PJ, Cain SM, Cullis PR, Snutch TP, MacVicar BA. The cellular mechanisms of neuronal swelling underlying cytotoxic edema. Cell. 161: 610-21. PMID 25910210 DOI: 10.1016/j.cell.2015.03.029  0.96
2015 Cain SM, Tyson JR, Jones KL, Snutch TP. Thalamocortical neurons display suppressed burst-firing due to an enhanced Ih current in a genetic model of absence epilepsy. PflüGers Archiv : European Journal of Physiology. 467: 1367-82. PMID 24953239 DOI: 10.1007/s00424-014-1549-4  0.96
2014 Ranzato E, Magnelli V, Martinotti S, Waheed Z, Cain SM, Snutch TP, Marchetti C, Burlando B. Epigallocatechin-3-gallate elicits Ca2+ spike in MCF-7 breast cancer cells: essential role of Cav3.2 channels. Cell Calcium. 56: 285-95. PMID 25260713 DOI: 10.1016/j.ceca.2014.09.002  0.96
2014 Powell KL, Cain SM, Snutch TP, O'Brien TJ. Low threshold T-type calcium channels as targets for novel epilepsy treatments. British Journal of Clinical Pharmacology. 77: 729-39. PMID 23834404 DOI: 10.1111/bcp.12205  0.96
2013 Cain SM, Snutch TP. T-type calcium channels in burst-firing, network synchrony, and epilepsy. Biochimica Et Biophysica Acta. 1828: 1572-8. PMID 22885138 DOI: 10.1016/j.bbamem.2012.07.028  0.96
2012 Tringham E, Powell KL, Cain SM, Kuplast K, Mezeyova J, Weerapura M, Eduljee C, Jiang X, Smith P, Morrison JL, Jones NC, Braine E, Rind G, Fee-Maki M, Parker D, et al. T-type calcium channel blockers that attenuate thalamic burst firing and suppress absence seizures. Science Translational Medicine. 4: 121ra19. PMID 22344687 DOI: 10.1126/scitranslmed.3003120  0.96
2011 Cain SM, Snutch TP. Voltage-gated calcium channels and disease. Biofactors (Oxford, England). 37: 197-205. PMID 21698699 DOI: 10.1002/biof.158  0.96
2010 Cain SM, Snutch TP. Contributions of T-type calcium channel isoforms to neuronal firing. Channels (Austin, Tex.). 4: 475-82. PMID 21139420 DOI: 10.4161/chan.4.6.14106  0.96
2010 David LS, Garcia E, Cain SM, Thau E, Tyson JR, Snutch TP. Splice-variant changes of the Ca(V)3.2 T-type calcium channel mediate voltage-dependent facilitation and associate with cardiac hypertrophy and development. Channels (Austin, Tex.). 4: 375-89. PMID 20699644 DOI: 10.4161/chan.4.5.12874  0.96
2009 Cain SM, Ruest T, Pimlott S, Patterson J, Duncan R, Dewar D, Sills GJ. High resolution micro-SPECT scanning in rats using 125I beta-CIT: effects of chronic treatment with carbamazepine. Epilepsia. 50: 1962-70. PMID 19453722 DOI: 10.1111/j.1528-1167.2009.02095.x  0.96
2009 Powell KL, Cain SM, Ng C, Sirdesai S, David LS, Kyi M, Garcia E, Tyson JR, Reid CA, Bahlo M, Foote SJ, Snutch TP, O'Brien TJ. A Cav3.2 T-type calcium channel point mutation has splice-variant-specific effects on function and segregates with seizure expression in a polygenic rat model of absence epilepsy. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 371-80. PMID 19144837 DOI: 10.1523/JNEUROSCI.5295-08.2009  0.96
2008 Cain SM, Meadows HJ, Dunlop J, Bushell TJ. mGlu4 potentiation of K(2P)2.1 is dependant on C-terminal dephosphorylation. Molecular and Cellular Neurosciences. 37: 32-9. PMID 17916432 DOI: 10.1016/j.mcn.2007.08.009  0.44
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