| Year |
Citation |
Score |
| 2022 |
Murugesan G, Prescott AR, Toth R, Campbell DG, Wells CM, MacKintosh C. Differential roles and regulation of the protein kinases PAK4, PAK5 and PAK6 in melanoma cells. The Biochemical Journal. PMID 35969127 DOI: 10.1042/BCJ20220184 |
0.382 |
|
| 2019 |
Malik N, Nirujogi RS, Peltier J, Macartney T, Wightman M, Prescott AR, Gourlay R, Trost M, Alessi DR, Karapetsas A. Phosphoproteomics reveals that the hVPS34 regulated SGK3 kinase specifically phosphorylates endosomal proteins including Syntaxin-7, Syntaxin-12, RFIP4 and WDR44. The Biochemical Journal. 476: 3081-3107. PMID 31665227 DOI: 10.1042/Bcj20190608 |
0.368 |
|
| 2019 |
Fulcher LJ, He Z, Mei L, Macartney TJ, Wood NT, Prescott AR, Whigham AJ, Varghese J, Gourlay R, Ball G, Clarke R, Campbell DG, Maxwell CA, Sapkota GP. FAM83D directs protein kinase CK1α to the mitotic spindle for proper spindle positioning. Embo Reports. e47495. PMID 31338967 DOI: 10.15252/embr.201847495 |
0.369 |
|
| 2019 |
Guo M, Härtlova A, Gierliński M, Prescott A, Castellvi J, Losa JH, Petersen SK, Wenzel UA, Dill BD, Emmerich CH, Ramon Y Cajal S, Russell DG, Trost M. Triggering MSR1 promotes JNK-mediated inflammation in IL-4-activated macrophages. The Embo Journal. PMID 31028084 DOI: 10.15252/Embj.2018100299 |
0.314 |
|
| 2018 |
Martínez-Fábregas J, Prescott A, van Kasteren S, Pedrioli DL, McLean I, Moles A, Reinheckel T, Poli V, Watts C. Lysosomal protease deficiency or substrate overload induces an oxidative-stress mediated STAT3-dependent pathway of lysosomal homeostasis. Nature Communications. 9: 5343. PMID 30559339 DOI: 10.1038/S41467-018-07741-6 |
0.377 |
|
| 2017 |
Logie L, Van Aalten L, Knebel A, Force T, Hastie CJ, MacLauchlan H, Campbell DG, Gourlay R, Prescott A, Davidson J, Fuller W, Sutherland C. Rab-GTPase binding effector protein 2 (RABEP2) is a primed substrate for Glycogen Synthase kinase-3 (GSK3). Scientific Reports. 7: 17682. PMID 29247183 DOI: 10.1038/S41598-017-17087-6 |
0.453 |
|
| 2017 |
Cummins TD, Wu KZL, Bozatzi P, Dingwell KS, Macartney TJ, Wood NT, Varghese J, Gourlay R, Campbell DG, Prescott A, Griffis E, Smith JC, Sapkota GP. FAM83G/PAWS1 controls cytoskeletal dynamics and cell migration through association with the SH3 adaptor CD2AP. Journal of Cell Science. PMID 29175910 DOI: 10.1242/Jcs.202390 |
0.372 |
|
| 2015 |
Stretton C, Hoffmann TM, Munson MJ, Prescott A, Taylor PM, Ganley IG, Hundal HS. GSK3-mediated raptor phosphorylation supports amino-acid-dependent mTORC1-directed signalling. The Biochemical Journal. 470: 207-21. PMID 26348909 DOI: 10.1042/Bj20150404 |
0.461 |
|
| 2015 |
Kazlauskaite A, Martínez-Torres RJ, Wilkie S, Kumar A, Peltier J, Gonzalez A, Johnson C, Zhang J, Hope AG, Peggie M, Trost M, van Aalten DM, Alessi DR, Prescott AR, Knebel A, et al. Binding to serine 65-phosphorylated ubiquitin primes Parkin for optimal PINK1-dependent phosphorylation and activation. Embo Reports. PMID 26116755 DOI: 10.15252/Embr.201540352 |
0.324 |
|
| 2015 |
Malik N, Vollmer S, Nanda SK, Lopez-Pelaez M, Prescott A, Gray N, Cohen P. Suppression of Interferon β gene transcription by inhibitors of Bromodomain and Extra-Terminal (BET) family members. The Biochemical Journal. PMID 25891802 DOI: 10.1042/Bj20141523 |
0.378 |
|
| 2014 |
Bago R, Malik N, Munson MJ, Prescott AR, Davies P, Sommer E, Shpiro N, Ward R, Cross D, Ganley IG, Alessi DR. Characterization of VPS34-IN1, a selective inhibitor of Vps34, reveals that the phosphatidylinositol 3-phosphate-binding SGK3 protein kinase is a downstream target of class III phosphoinositide 3-kinase. The Biochemical Journal. 463: 413-27. PMID 25177796 DOI: 10.1042/Bj20140889 |
0.339 |
|
| 2014 |
Gawden-Bone C, West MA, Morrison VL, Edgar AJ, McMillan SJ, Dill BD, Trost M, Prescott A, Fagerholm SC, Watts C. A crucial role for β2 integrins in podosome formation, dynamics and Toll-like-receptor-signaled disassembly in dendritic cells. Journal of Cell Science. 127: 4213-24. PMID 25086067 DOI: 10.1242/Jcs.151167 |
0.325 |
|
| 2014 |
Banerjee S, Zagórska A, Deak M, Campbell DG, Prescott AR, Alessi DR. Interplay between Polo kinase, LKB1-activated NUAK1 kinase, PP1βMYPT1 phosphatase complex and the SCFβTrCP E3 ubiquitin ligase. The Biochemical Journal. 461: 233-45. PMID 24785407 DOI: 10.1042/Bj20140408 |
0.641 |
|
| 2014 |
Banerjee S, Buhrlage SJ, Huang HT, Deng X, Zhou W, Wang J, Traynor R, Prescott AR, Alessi DR, Gray NS. Characterization of WZ4003 and HTH-01-015 as selective inhibitors of the LKB1-tumour-suppressor-activated NUAK kinases. The Biochemical Journal. 457: 215-25. PMID 24171924 DOI: 10.1042/Bj20131152 |
0.632 |
|
| 2013 |
Groves MJ, Johnson CE, James J, Prescott AR, Cunningham J, Haydock S, Pepper C, Fegan C, Pirrie L, Westwood NJ, Coates PJ, Ganley IG, Tauro S. p53 and cell cycle independent dysregulation of autophagy in chronic lymphocytic leukaemia. British Journal of Cancer. 109: 2434-44. PMID 24091621 DOI: 10.1038/Bjc.2013.601 |
0.332 |
|
| 2013 |
Ordureau A, Enesa K, Nanda S, Le Francois B, Peggie M, Prescott A, Albert PR, Cohen P. DEAF1 is a Pellino1-interacting protein required for interferon production by Sendai virus and double-stranded RNA. The Journal of Biological Chemistry. 288: 24569-80. PMID 23846693 DOI: 10.1074/Jbc.M113.479550 |
0.358 |
|
| 2013 |
Morrison VL, MacPherson M, Savinko T, Lek HS, Prescott A, Fagerholm SC. The β2 integrin-kindlin-3 interaction is essential for T-cell homing but dispensable for T-cell activation in vivo. Blood. 122: 1428-36. PMID 23823319 DOI: 10.1182/Blood-2013-02-484998 |
0.339 |
|
| 2013 |
Lek HS, Morrison VL, Conneely M, Campbell PA, McGloin D, Kliche S, Watts C, Prescott A, Fagerholm SC. The spontaneously adhesive leukocyte function-associated antigen-1 (LFA-1) integrin in effector T cells mediates rapid actin- and calmodulin-dependent adhesion strengthening to ligand under shear flow. The Journal of Biological Chemistry. 288: 14698-708. PMID 23585567 DOI: 10.1074/Jbc.M112.430918 |
0.404 |
|
| 2013 |
McMillan SJ, Sharma RS, McKenzie EJ, Richards HE, Zhang J, Prescott A, Crocker PR. Siglec-E is a negative regulator of acute pulmonary neutrophil inflammation and suppresses CD11b β2-integrin-dependent signaling. Blood. 121: 2084-94. PMID 23315163 DOI: 10.1182/Blood-2012-08-449983 |
0.31 |
|
| 2013 |
MacKenzie KF, Clark K, Naqvi S, McGuire VA, Nöehren G, Kristariyanto Y, van den Bosch M, Mudaliar M, McCarthy PC, Pattison MJ, Pedrioli PG, Barton GJ, Toth R, Prescott A, Arthur JS. PGE(2) induces macrophage IL-10 production and a regulatory-like phenotype via a protein kinase A-SIK-CRTC3 pathway. Journal of Immunology (Baltimore, Md. : 1950). 190: 565-77. PMID 23241891 DOI: 10.4049/Jimmunol.1202462 |
0.391 |
|
| 2011 |
Hutten S, Prescott A, James J, Riesenberg S, Boulon S, Lam YW, Lamond AI. An intranucleolar body associated with rDNA. Chromosoma. 120: 481-99. PMID 21698343 DOI: 10.1007/S00412-011-0327-8 |
0.304 |
|
| 2011 |
Bouskila M, Esoof N, Gay L, Fang EH, Deak M, Begley MJ, Cantley LC, Prescott A, Storey KG, Alessi DR. TTBK2 kinase substrate specificity and the impact of spinocerebellar-ataxia-causing mutations on expression, activity, localization and development. The Biochemical Journal. 437: 157-67. PMID 21548880 DOI: 10.1042/Bj20110276 |
0.42 |
|
| 2011 |
MacPherson M, Lek HS, Prescott A, Fagerholm SC. A systemic lupus erythematosus-associated R77H substitution in the CD11b chain of the Mac-1 integrin compromises leukocyte adhesion and phagocytosis. The Journal of Biological Chemistry. 286: 17303-10. PMID 21454473 DOI: 10.1074/Jbc.M110.182998 |
0.394 |
|
| 2011 |
Deng X, Dzamko N, Prescott A, Davies P, Liu Q, Yang Q, Lee JD, Patricelli MP, Nomanbhoy TK, Alessi DR, Gray NS. Characterization of a selective inhibitor of the Parkinson's disease kinase LRRK2. Nature Chemical Biology. 7: 203-5. PMID 21378983 DOI: 10.1038/Nchembio.538 |
0.331 |
|
| 2011 |
Richardson C, Sakamoto K, de los Heros P, Deak M, Campbell DG, Prescott AR, Alessi DR. Regulation of the NKCC2 ion cotransporter by SPAK-OSR1-dependent and -independent pathways. Journal of Cell Science. 124: 789-800. PMID 21321328 DOI: 10.1242/Jcs.077230 |
0.31 |
|
| 2011 |
Dissanayake K, Toth R, Blakey J, Olsson O, Campbell DG, Prescott AR, MacKintosh C. ERK/p90(RSK)/14-3-3 signalling has an impact on expression of PEA3 Ets transcription factors via the transcriptional repressor capicúa. The Biochemical Journal. 433: 515-25. PMID 21087211 DOI: 10.1042/Bj20101562 |
0.329 |
|
| 2010 |
Dzamko N, Deak M, Hentati F, Reith AD, Prescott AR, Alessi DR, Nichols RJ. Inhibition of LRRK2 kinase activity leads to dephosphorylation of Ser(910)/Ser(935), disruption of 14-3-3 binding and altered cytoplasmic localization. The Biochemical Journal. 430: 405-13. PMID 20659021 DOI: 10.1042/Bj20100784 |
0.347 |
|
| 2010 |
Nichols RJ, Dzamko N, Morrice NA, Campbell DG, Deak M, Ordureau A, Macartney T, Tong Y, Shen J, Prescott AR, Alessi DR. 14-3-3 binding to LRRK2 is disrupted by multiple Parkinson's disease-associated mutations and regulates cytoplasmic localization. The Biochemical Journal. 430: 393-404. PMID 20642453 DOI: 10.1042/Bj20100483 |
0.308 |
|
| 2010 |
Gawden-Bone C, Zhou Z, King E, Prescott A, Watts C, Lucocq J. Dendritic cell podosomes are protrusive and invade the extracellular matrix using metalloproteinase MMP-14. Journal of Cell Science. 123: 1427-37. PMID 20356925 DOI: 10.1242/Jcs.056515 |
0.319 |
|
| 2010 |
Zagórska A, Deak M, Campbell DG, Banerjee S, Hirano M, Aizawa S, Prescott AR, Alessi DR. New roles for the LKB1-NUAK pathway in controlling myosin phosphatase complexes and cell adhesion. Science Signaling. 3: ra25. PMID 20354225 DOI: 10.1126/Scisignal.2000616 |
0.637 |
|
| 2009 |
Yin Y, Bangs F, Paton IR, Prescott A, James J, Davey MG, Whitley P, Genikhovich G, Technau U, Burt DW, Tickle C. The Talpid3 gene (KIAA0586) encodes a centrosomal protein that is essential for primary cilia formation. Development (Cambridge, England). 136: 655-64. PMID 19144723 DOI: 10.1242/Dev.028464 |
0.344 |
|
| 2008 |
Martin-Granados C, Philp A, Oxenham SK, Prescott AR, Cohen PT. Depletion of protein phosphatase 4 in human cells reveals essential roles in centrosome maturation, cell migration and the regulation of Rho GTPases. The International Journal of Biochemistry & Cell Biology. 40: 2315-32. PMID 18487071 DOI: 10.1016/j.biocel.2008.03.021 |
0.328 |
|
| 2007 |
Zagórska A, Pozo-Guisado E, Boudeau J, Vitari AC, Rafiqi FH, Thastrup J, Deak M, Campbell DG, Morrice NA, Prescott AR, Alessi DR. Regulation of activity and localization of the WNK1 protein kinase by hyperosmotic stress. The Journal of Cell Biology. 176: 89-100. PMID 17190791 DOI: 10.1083/Jcb.200605093 |
0.34 |
|
| 2006 |
Göransson O, Deak M, Wullschleger S, Morrice NA, Prescott AR, Alessi DR. Regulation of the polarity kinases PAR-1/MARK by 14-3-3 interaction and phosphorylation. Journal of Cell Science. 119: 4059-70. PMID 16968750 DOI: 10.1242/Jcs.03097 |
0.339 |
|
| 2006 |
Jaleel M, Villa F, Deak M, Toth R, Prescott AR, Van Aalten DMF, Alessi DR. The ubiquitin-associated domain of AMPK-related kinases regulates conformation and LKB1-mediated phosphorylation and activation Biochemical Journal. 394: 545-555. PMID 16396636 DOI: 10.1042/Bj20051844 |
0.315 |
|
| 2005 |
Al-Hakim AK, Göransson O, Deak M, Toth R, Campbell DG, Morrice NA, Prescott AR, Alessi DR. 14-3-3 cooperates with LKB1 to regulate the activity and localization of QSK and SIK Journal of Cell Science. 118: 5661-5673. PMID 16306228 DOI: 10.1242/Jcs.02670 |
0.357 |
|
| 2004 |
Boudeau J, Scott JW, Resta N, Deak M, Kieloch A, Komander D, Hardie DG, Prescott AR, van Aalten DM, Alessi DR. Analysis of the LKB1-STRAD-MO25 complex. Journal of Cell Science. 117: 6365-75. PMID 15561763 DOI: 10.1242/Jcs.01571 |
0.325 |
|
| 2004 |
McManus EJ, Collins BJ, Ashby PR, Prescott AR, Murray-Tait V, Armit LJ, Arthur JS, Alessi DR. The in vivo role of PtdIns(3,4,5)P3 binding to PDK1 PH domain defined by knockin mutation. The Embo Journal. 23: 2071-82. PMID 15116068 DOI: 10.1038/Sj.Emboj.7600218 |
0.337 |
|
| 2004 |
Paron I, D'Elia A, D'Ambrosio C, Scaloni A, D'Aurizio F, Prescott A, Damante G, Tell G. A proteomic approach to identify early molecular targets of oxidative stress in human epithelial lens cells. The Biochemical Journal. 378: 929-37. PMID 14678012 DOI: 10.1042/Bj20031190 |
0.341 |
|
| 2004 |
Vitari AC, Deak M, Collins BJ, Morrice N, Prescott AR, Phelan A, Humphreys S, Alessi DR. WNK1, the kinase mutated in an inherited high-blood-pressure syndrome, is a novel PKB (protein kinase B)/Akt substrate Biochemical Journal. 378: 257-268. PMID 14611643 DOI: 10.1042/Bj20031692 |
0.355 |
|
| 2003 |
Girão H, Pereira P, Ramalho J, Quinlan R, Prescott A. Cholesterol oxides mediated changes in cytoskeletal organisation involves Rho GTPases. Experimental Cell Research. 291: 502-13. PMID 14644170 DOI: 10.1016/J.Yexcr.2003.08.002 |
0.363 |
|
| 2003 |
Trinkle-Mulcahy L, Andrews PD, Wickramasinghe S, Sleeman J, Prescott A, Lam YW, Lyon C, Swedlow JR, Lamond AI. Time-lapse imaging reveals dynamic relocalization of PP1γ throughout the mammalian cell cycle Molecular Biology of the Cell. 14: 107-117. PMID 12529430 DOI: 10.1091/Mbc.E02-07-0376 |
0.37 |
|
| 2002 |
Eskelinen EL, Prescott AR, Cooper J, Brachmann SM, Wang L, Tang X, Backer JM, Lucocq JM. Inhibition of autophagy in mitotic animal cells. Traffic (Copenhagen, Denmark). 3: 878-93. PMID 12453151 DOI: 10.1034/J.1600-0854.2002.31204.X |
0.36 |
|
| 2002 |
Rena G, Woods YL, Prescott AR, Peggie M, Unterman TG, Williams MR, Cohen P. Two novel phosphorylation sites on FKHR that are critical for its nuclear exclusion. The Embo Journal. 21: 2263-71. PMID 11980723 DOI: 10.1093/Emboj/21.9.2263 |
0.328 |
|
| 2001 |
Rena G, Prescott AR, Guo S, Cohen P, Unterman TG. Roles of the forkhead in rhabdomyosarcoma (FKHR) phosphorylation sites in regulating 14-3-3 binding, transactivation and nuclear targetting. The Biochemical Journal. 354: 605-12. PMID 11237865 DOI: 10.1042/0264-6021:3540605 |
0.36 |
|
| 2001 |
Fagerholm SC, Prescott A, Cohen P, Gahmberg CG. An essential role for calmodulin in regulating human T cell aggregation. Febs Letters. 491: 131-136. PMID 11226435 DOI: 10.1016/S0014-5793(01)02182-2 |
0.387 |
|
| 2001 |
Lengler J, Krausz E, Tomarev S, Prescott A, Quinlan RA, Graw J. Antagonistic action of Six3 and Prox1 at the γ-crystallin promoter Nucleic Acids Research. 29: 515-526. PMID 11139622 DOI: 10.1093/Nar/29.2.515 |
0.346 |
|
| 2000 |
Herbert TP, Fåhraeus R, Prescott A, Lane DP, Proud CG. Rapid induction of apoptosis mediated by peptides that bind initiation factor eIF4E. Current Biology : Cb. 10: 793-6. PMID 10898981 DOI: 10.1016/S0960-9822(00)00567-4 |
0.336 |
|
| 2000 |
PEYROLLIER K, HAJDUCH E, GRAY A, LITHERLAND GJ, PRESCOTT AR, LESLIE NR, HUNDAL HS. A role for the actin cytoskeleton in the hormonal and growth-factor-mediated activation of protein kinase B Biochemical Journal. 352: 617-622. DOI: 10.1042/BJ3520617 |
0.333 |
|
| 1998 |
Salt I, Celler JW, Hawley SA, Prescott A, Woods A, Carling D, Hardie DG. AMP-activated protein kinase: greater AMP dependence, and preferential nuclear localization, of complexes containing the alpha2 isoform. The Biochemical Journal. 334: 177-87. PMID 9693118 DOI: 10.1042/Bj3340177 |
0.339 |
|
| 1996 |
Copeland L, Spraggon C, Dewar D, Spruce B, Prescott A. PROENKEPHALIN, A REGULATOR OF CELL DEATH AND SURVIVAL, IS LOCALISED TO SEVERAL DISTINCT CELL COMPARTMENTS DURING EYE LENS CELL DIFFERENTIATION AND COLOCALISES WITH P53 IN THE LENS FIBRE CELL NUCLEUS Biochemical Society Transactions. 24: 571S-571S. DOI: 10.1042/Bst024571Sa |
0.322 |
|
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