Alpa Khatri - Related publications

Affiliations: 
Rollins Research Center, Emory University 
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50 most relevant papers in past 60 days:
Year Citation  Score
2020 Salazar H, Mischke S, Plested AJR. Measurements of the Timescale and Conformational Space of AMPA Receptor Desensitization. Biophysical Journal. PMID 32559412 DOI: 10.1016/j.bpj.2020.05.029   
2020 Chou TH, Tajima N, Romero-Hernandez A, Furukawa H. Structural Basis of Functional Transitions in Mammalian NMDA Receptors. Cell. PMID 32610085 DOI: 10.1016/j.cell.2020.05.052   
2020 Falk-Petersen CB, Tsonkov TM, Nielsen MS, Harpsøe K, Bundgaard C, Frølund B, Kristiansen U, Gloriam DE, Wellendorph P. Discovery of a new class of orthosteric antagonists with nanomolar potency at extrasynaptic GABA receptors. Scientific Reports. 10: 10078. PMID 32572053 DOI: 10.1038/s41598-020-66821-0   
2020 Rumpret M, Drylewicz J, Ackermans LJE, Borghans JAM, Medzhitov R, Meyaard L. Functional categories of immune inhibitory receptors. Nature Reviews. Immunology. PMID 32612208 DOI: 10.1038/s41577-020-0352-z   
2020 Park J, Fu Z, Frangaj A, Liu J, Mosyak L, Shen T, Slavkovich VN, Ray KM, Taura J, Cao B, Geng Y, Zuo H, Kou Y, Grassucci R, Chen S, et al. Structure of human GABA receptor in an inactive state. Nature. PMID 32581365 DOI: 10.1038/s41586-020-2452-0   
2020 Germann AL, Reichert DE, Burbridge AB, Pierce SR, Evers AS, Steinbach JH, Akk G. Analysis of modulation of the ρ1 GABAA receptor by combinations of inhibitory and potentiating neurosteroids reveals shared and distinct binding sites. Molecular Pharmacology. PMID 32675382 DOI: 10.1124/mol.120.119842   
2020 Lillo A, Martínez-Pinilla E, Reyes-Resina I, Navarro G, Franco R. Adenosine A and A Receptors Are Able to Interact with Each Other. A Further Piece in the Puzzle of Adenosine Receptor-Mediated Signaling. International Journal of Molecular Sciences. 21. PMID 32709103 DOI: 10.3390/ijms21145070   
2020 Yu Liao VW, Kusay AS, Balle T, Ahring PK. Heterologous expression of concatenated nicotine acetylcholine receptors: pros and cons of subunit concatenation and recommendations for construct designs. British Journal of Pharmacology. PMID 32627170 DOI: 10.1111/bph.15188   
2020 Ladurner A, Linder T, Wang L, Hiebl V, Schuster D, Schnürch M, Mihovilovic MD, Atanasov AG, Dirsch VM. Characterization of a Structural Leoligin Analog as Farnesoid X Receptor Agonist and Modulator of Cholesterol Transport. Planta Medica. PMID 32485752 DOI: 10.1055/a-1171-8357   
2020 Burada AP, Vinnakota R, Kumar J. The Architecture of GluD2 Ionotropic Delta Glutamate Receptor Elucidated by cryo-EM. Journal of Structural Biology. 107546. PMID 32512155 DOI: 10.1016/j.jsb.2020.107546   
2020 Dalby NO, Falk-Petersen CB, Leurs U, Scholze P, Krall J, Frølund B, Wellendorph P. Silencing of spontaneous activity at α4β1/3δ GABA receptors in hippocampal granule cells reveals different ligand pharmacology. British Journal of Pharmacology. PMID 32484592 DOI: 10.1111/bph.15146   
2020 Mattedi G, Acosta-Gutiérrez S, Clark T, Gervasio FL. A combined activation mechanism for the glucagon receptor. Proceedings of the National Academy of Sciences of the United States of America. PMID 32571939 DOI: 10.1073/pnas.1921851117   
2020 Abbott JA, Popescu GK. Hydroxynorketamine Blocks NMDA Receptor Currents by Binding to Closed Receptors. Molecular Pharmacology. PMID 32606205 DOI: 10.1124/mol.120.119784   
2020 Fischer JP, Els-Heindl S, Beck-Sickinger AG. Adrenomedullin - Current Perspective on a Peptide Hormone with Significant Therapeutic Potential. Peptides. 170347. PMID 32569606 DOI: 10.1016/j.peptides.2020.170347   
2020 Che C, Zeng Y, Xu Y, Lu H, Xu Y, Zhang X, Xiao Y, Li JQ, Qin Z. APAn, a Class of ABA Receptor Agonism/antagonism Switching Probes. Journal of Agricultural and Food Chemistry. PMID 32687337 DOI: 10.1021/acs.jafc.0c02154   
2020 Liu X, Guo L, Liang C. [Research progress on electroencephalogram characteristics of anti-N-methyl-D-aspartate receptor encephalitis]. Zhejiang Da Xue Xue Bao. Yi Xue Ban = Journal of Zhejiang University. Medical Sciences. 49: 118-123. PMID 32621409   
2020 Stephens BS, Ngo T, Kufareva I, Handel TM. Functional anatomy of the full-length CXCR4-CXCL12 complex systematically dissected by quantitative model-guided mutagenesis. Science Signaling. 13. PMID 32665413 DOI: 10.1126/scisignal.aay5024   
2020 Friedman S, Tauber M, Ben-Chaim Y. Sodium ions allosterically modulate the M2 muscarinic receptor. Scientific Reports. 10: 11177. PMID 32636499 DOI: 10.1038/s41598-020-68133-9   
2020 Krintel C, Dorosz J, Larsen AH, Seneca Thorsen T, Venskutonytė R, Mirza O, Gajhede M, Boesen T, Kastrup JS. Binding of a negative allosteric modulator and competitive antagonist can occur simultaneously at the ionotropic glutamate receptor GluA2. The Febs Journal. PMID 32543078 DOI: 10.1111/febs.15455   
2020 Zhang X, Meng R, Wang H, Xing J. Differential Effects of Components in Artemisia annua Extract on the Induction of Drug-Metabolizing Enzyme Expression Mediated by Nuclear Receptors. Planta Medica. PMID 32557519 DOI: 10.1055/a-1178-0852   
2020 Amata E, Dichiara M, Gentile D, Marrazzo A, Turnaturi R, Arena E, La Mantia A, Tomasello BR, Acquaviva R, Di Giacomo C, Rescifina A, Prezzavento O. Sigma Receptor Ligands Carrying a Nitric Oxide Donor Nitrate Moiety: Synthesis, In Silico, and Biological Evaluation. Acs Medicinal Chemistry Letters. 11: 889-894. PMID 32435401 DOI: 10.1021/acsmedchemlett.9b00661   
2020 Intagliata S, Sharma A, King TI, Mesangeau C, Seminerio M, Chin FT, Wilson LL, Matsumoto RR, McLaughlin JP, Avery BA, McCurdy CR. Discovery of a Highly Selective Sigma-2 Receptor Ligand, 1-(4-(6,7-Dimethoxy-3,4-dihydroisoquinolin-2(1H)-yl)butyl)-3-methyl-1H-benzo[d]imidazol-2(3H)-one (CM398), with Drug-Like Properties and Antinociceptive Effects In Vivo. The Aaps Journal. 22: 94. PMID 32691179 DOI: 10.1208/s12248-020-00472-x   
2020 Zhao B, Li W, Sun L, Fu W. The Use of Computational Approaches in the Discovery and Mechanism Study of Opioid Analgesics. Frontiers in Chemistry. 8: 335. PMID 32500054 DOI: 10.3389/fchem.2020.00335   
2020 Pflüger P, Regner GG, Luft JG, Gonçalves DA, Krebs C, Fontenla JA, Pereira P. Gamma-decanolactone attenuates acute and chronic seizures in mice: a possible role of adenosine A1 receptors. Behavioural Pharmacology. PMID 32701527 DOI: 10.1097/FBP.0000000000000554   
2020 Evenseth LSM, Ocello R, Gabrielsen M, Masetti M, Recanatini M, Sylte I, Cavalli A. Exploring Conformational Dynamics of the Extracellular Domain of the GABA Receptor: A Path-Metadynamics Study. Journal of Chemical Information and Modeling. 60: 2294-2303. PMID 32233432 DOI: 10.1021/acs.jcim.0c00163   
2020 Al Noman MA, Kyzer J, Chung SSW, Wolgemuth DJ, Georg GI. Retinoic acid receptor antagonists for male contraception: Current status. Biology of Reproduction. PMID 32671394 DOI: 10.1093/biolre/ioaa122   
2020 Richendrfer HA, Levy MM, Elsaid KA, Schmidt TA, Zhang L, Cabezas R, Jay GD. Recombinant Human Proteoglycan-4 Mediates Interleukin-6 Response in Both Human and Mouse Endothelial Cells Induced Into a Sepsis Phenotype. Critical Care Explorations. 2: e0126. PMID 32695993 DOI: 10.1097/CCE.0000000000000126   
2020 Chen BP, Huang XX, Dong DM, Wu H, Zhu TQ, Wang BF. The role of NMDA receptors in rat propofol self-administration. Bmc Anesthesiology. 20: 149. PMID 32539742 DOI: 10.1186/s12871-020-01056-0   
2020 Papasergi-Scott MM, Robertson MJ, Seven AB, Panova O, Mathiesen JM, Skiniotis G. Structures of metabotropic GABA receptor. Nature. PMID 32580208 DOI: 10.1038/s41586-020-2469-4   
2020 Chin AC, Yovanno RA, Wied TJ, Gershman A, Lau AY. D-Serine Potently Drives Ligand-Binding Domain Closure in the Ionotropic Glutamate Receptor GluD2. Structure (London, England : 1993). PMID 32735769 DOI: 10.1016/j.str.2020.07.005   
2020 Ito-Harashima S, Matano M, Onishi K, Nomura T, Nakajima S, Ebata S, Shiizaki K, Kawanishi M, Yagi T. Construction of reporter gene assays using and mutant yeasts for enhanced detection of various sex steroids. Genes and Environment : the Official Journal of the Japanese Environmental Mutagen Society. 42: 20. PMID 32514322 DOI: 10.1186/s41021-020-00159-x   
2020 Bondarev AD, Attwood MM, Jonsson J, Chubarev VN, Tarasov VV, Schiöth HB. Opportunities and challenges for drug discovery in modulating Adhesion G protein-coupled receptor (GPCR) functions. Expert Opinion On Drug Discovery. 1-17. PMID 32648789 DOI: 10.1080/17460441.2020.1791075   
2020 Rauschenberger V, Wardenburg NV, Schaefer N, Ogino K, Hirata H, Lillesaar C, Kluck CJ, Meinck HM, Borrmann M, Weishaupt A, Doppler K, Wickel J, Geis C, Sommer C, Villmann C. GlyR autoantibodies impair receptor function and induce motor dysfunction. Annals of Neurology. PMID 32588476 DOI: 10.1002/ana.25832   
2020 Yao D, Li J, Yoshida M, Sessle BJ. NMDA and Purinergic Processes Modulate Neck Muscle Activity Evoked by Noxious Stimulation of Dura. Journal of Oral Pathology & Medicine : Official Publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology. PMID 32531859 DOI: 10.1111/jop.13072   
2020 Kim HR, Xu J, Maeda S, Duc NM, Ahn D, Du Y, Chung KY. Structural mechanism underlying primary and secondary coupling between GPCRs and the Gi/o family. Nature Communications. 11: 3160. PMID 32572026 DOI: 10.1038/s41467-020-16975-2   
2020 Sun HS, Yang QR, Bai YY, Hu NW, Liu DX, Qin CY. Gene testing for osteonecrosis of the femoral head in systemic lupus erythematosus using targeted next-generation sequencing: A pilot study. World Journal of Clinical Cases. 8: 2530-2541. PMID 32607330 DOI: 10.12998/wjcc.v8.i12.2530   
2020 Liu K, Wu L, Yuan S, Wu M, Xu Y, Sun Q, Li S, Zhao S, Hua T, Liu ZJ. Structural basis of CXC chemokine receptor 2 activation and signalling. Nature. PMID 32610344 DOI: 10.1038/s41586-020-2492-5   
2020 Nikitin VP, Solntseva SV, Kozyrev SA. Peculiarities in Synthesis of Proteins Implicated in Memory Reconsolidation and Induction of Amnesia. Bulletin of Experimental Biology and Medicine. 169: 187-191. PMID 32651811 DOI: 10.1007/s10517-020-04847-0   
2020 Magno AL, Leatherbarrow KM, Brown SJ, Wilson SG, Walsh JP, Ward BK. Functional Analysis of Calcium-Sensing Receptor Variants Identified in Families Provisionally Diagnosed with Familial Hypocalciuric Hypercalcaemia. Calcified Tissue International. PMID 32638038 DOI: 10.1007/s00223-020-00715-1   
2020 Tasma Z, Wills P, Hay DL, Walker CS. Agonist bias and agonist-dependent antagonism at corticotrophin releasing factor receptors. Pharmacology Research & Perspectives. 8: e00595. PMID 32529807 DOI: 10.1002/prp2.595   
2020 Chiocchetti R, Rinnovati R, Tagliavia C, Stanzani A, Galiazzo G, Giancola F, De Silva M, Capodanno Y, Spadari A. Localisation of cannabinoid and cannabinoid-related receptors in the equine dorsal root ganglia. Equine Veterinary Journal. PMID 32524649 DOI: 10.1111/evj.13305   
2020 Gillet C, Kurth S, Kuenzel T. Muscarinic modulation of M and h currents in gerbil spherical bushy cells. Plos One. 15: e0226954. PMID 31940388 DOI: 10.1371/journal.pone.0226954   
2020 Ledderose C, Bromberger S, Slubowski CJ, Sueyoshi K, Junger WG. Frontline Science: P2Y11 receptors support T cell activation by directing mitochondrial trafficking to the immune synapse. Journal of Leukocyte Biology. PMID 32531829 DOI: 10.1002/JLB.2HI0520-191R   
2020 Corrie LW, Stokes C, Wilkerson JL, Carroll FI, McMahon LR, Papke RL. Nicotinic Acetylcholine Receptor Accessory Subunits Determine the Activity Profile of Epibatidine Derivatives. Molecular Pharmacology. PMID 32690626 DOI: 10.1124/molpharm.120.000037   
2020 Sato K. Why is prepulse inhibition disrupted in schizophrenia? Medical Hypotheses. 143: 109901. PMID 32502900 DOI: 10.1016/j.mehy.2020.109901   
2020 Zaccor NW, Sumner CJ, Snyder SH. The nonselective cation channel TRPV4 inhibits angiotensin II receptors. The Journal of Biological Chemistry. PMID 32493776 DOI: 10.1074/jbc.RA120.014325   
2020 Nguyen T, Marusich J, Li JX, Zhang Y. Neuropeptide FF and Its Receptors: Therapeutic Applications and Ligand Development. Journal of Medicinal Chemistry. PMID 32673481 DOI: 10.1021/acs.jmedchem.0c00643   
2020 Kim TK, Lee MS. Innate immune receptors in type 1 diabetes: the relationship to cell death-associated inflammation. Biochemical Society Transactions. PMID 32510139 DOI: 10.1042/BST20200131   
2020 Yang X, Dilweg MA, Osemwengie D, Burggraaff L, van der Es D, Heitman LH, IJzerman AP. Design and Pharmacological Profile of a Novel Covalent Partial Agonist for the Adenosine A Receptor. Biochemical Pharmacology. 114144. PMID 32653590 DOI: 10.1016/j.bcp.2020.114144   
2020 Möller J, Isbilir A, Sungkaworn T, Osberg B, Karathanasis C, Sunkara V, Grushevskyi EO, Bock A, Annibale P, Heilemann M, Schütte C, Lohse MJ. Single-molecule analysis reveals agonist-specific dimer formation of µ-opioid receptors. Nature Chemical Biology. PMID 32541966 DOI: 10.1038/s41589-020-0566-1