Denise C. Liotta - Related publications

Affiliations: 
Emory University, Atlanta, GA 
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50 most relevant papers in past 60 days:
Year Citation  Score
2020 Ye N, Qin W, Tian S, Xu Q, Wold EA, Zhou J, Zhen XC. Small Molecules Selectively Targeting Sigma-1 Receptor for the Treatment of Neurological Diseases. Journal of Medicinal Chemistry. PMID 33111525 DOI: 10.1021/acs.jmedchem.0c01192   
2020 Li M, Huang C, Wu X, Ding F, Hu Z, Zhu Y, Zhao L, Hou L, Chen H, Wang H, Xu J, Tang D. The optimization of a novel selective antagonist for human M muscarinic acetylcholine receptor. Bioorganic & Medicinal Chemistry Letters. 30: 127632. PMID 33132116 DOI: 10.1016/j.bmcl.2020.127632   
2020 Pollok S, Reiner A. Subunit-selective iGluR antagonists can potentiate heteromeric receptor responses by blocking desensitization. Proceedings of the National Academy of Sciences of the United States of America. 117: 25851-25858. PMID 32999066 DOI: 10.1073/pnas.2007471117   
2020 Kim JH, Marton J, Ametamey SM, Cumming P. A Review of Molecular Imaging of Glutamate Receptors. Molecules (Basel, Switzerland). 25. PMID 33081223 DOI: 10.3390/molecules25204749   
2020 Rajan R, Schepmann D, Schreiber JA, Seebohm G, Wünsch B. Synthesis of GluN2A-selective NMDA receptor antagonists with an electron-rich aromatic B-ring. European Journal of Medicinal Chemistry. 112939. PMID 33162207 DOI: 10.1016/j.ejmech.2020.112939   
2020 Ramesh S, Park S, Call MJ, Im W, Call ME. Experimentally Guided Computational Methods Yield Highly Accurate Insights into Transmembrane Interactions within the T Cell Receptor Complex. The Journal of Physical Chemistry. B. PMID 33030343 DOI: 10.1021/acs.jpcb.0c06403   
2020 Jones EM, Lubock NB, Venkatakrishnan AJ, Wang J, Tseng AM, Paggi JM, Latorraca NR, Cancilla D, Satyadi M, Davis JE, Babu MM, Dror RO, Kosuri S. Structural and functional characterization of G protein-coupled receptors with deep mutational scanning. Elife. 9. PMID 33084570 DOI: 10.7554/eLife.54895   
2020 Liu YP, Wu X, Meng JH, Yao J, Wang BJ. Functional Analysis of the 3' Untranslated Region of the Human Gene in Regulating Gene Expression in vitro. Neuropsychiatric Disease and Treatment. 16: 2361-2370. PMID 33116535 DOI: 10.2147/NDT.S268753   
2020 Reeh K, Summers PA, Gould IR, Woscholski R, Vilar R. Design, synthesis and evaluation of a tripodal receptor for phosphatidylinositol phosphates. Scientific Reports. 10: 18450. PMID 33116198 DOI: 10.1038/s41598-020-75484-w   
2020 Norel X, Sugimoto Y, Ozen G, Abdelazeem H, Amgoud Y, Bouhadoun A, Bassiouni W, Goepp M, Mani S, Manikpurage HD, Senbel A, Longrois D, Heinemann A, Yao C, Clapp LH. International Union of Basic and Clinical Pharmacology. CIX. Differences and Similarities between Human and Rodent Prostaglandin E Receptors (EP1-4) and Prostacyclin Receptor (IP): Specific Roles in Pathophysiologic Conditions. Pharmacological Reviews. 72: 910-968. PMID 32962984 DOI: 10.1124/pr.120.019331   
2020 Devenish SO, Winters BL, Anderson LL, Arnold JC, McGregor IS, Vaughan CW, Chebib M, Absalom NL. The anticonvulsant zonisamide positively modulates recombinant and native glycine receptors at clinically relevant concentrations. Neuropharmacology. 108371. PMID 33122032 DOI: 10.1016/j.neuropharm.2020.108371   
2020 Dvořák Z, Sokol H, Mani S. Drug Mimicry: Promiscuous Receptors PXR and AhR, and Microbial Metabolite Interactions in the Intestine. Trends in Pharmacological Sciences. PMID 33097284 DOI: 10.1016/j.tips.2020.09.013   
2020 Grosicki M, Adami M, Micheloni C, Głuch-Lutwin M, Siwek A, Latacz G, Łażewska D, Więcek M, Reiner D, Stark H, Chlopicki S, Kieć-Kononowicz K. Eosinophils adhesion assay as a tool for phenotypic drug screening - The pharmacology of 1,3,5 - Triazine and 1h-indole like derivatives against the human histamine H receptor. European Journal of Pharmacology. 173611. PMID 33017589 DOI: 10.1016/j.ejphar.2020.173611   
2020 Pieterse L, van der Walt MM, Terre'Blanche G. C2-substituted quinazolinone derivatives exhibit A and/or A adenosine receptor affinities in the low micromolar range. Bioorganic & Medicinal Chemistry Letters. 30: 127274. PMID 32631506 DOI: 10.1016/j.bmcl.2020.127274   
2020 Serrano-Marín J, Reyes-Resina I, Martínez-Pinilla E, Navarro G, Franco R. Natural Compounds as Guides for the Discovery of Drugs Targeting G-Protein-Coupled Receptors. Molecules (Basel, Switzerland). 25. PMID 33143389 DOI: 10.3390/molecules25215060   
2020 Işbilir A, Möller J, Arimont M, Bobkov V, Perpiñá-Viciano C, Hoffmann C, Inoue A, Heukers R, de Graaf C, Smit MJ, Annibale P, Lohse MJ. Advanced fluorescence microscopy reveals disruption of dynamic CXCR4 dimerization by subpocket-specific inverse agonists. Proceedings of the National Academy of Sciences of the United States of America. PMID 33148803 DOI: 10.1073/pnas.2013319117   
2020 Pandey S, Saha S, Shukla AK. Transmitting the Signal: Structure of the β1-Adrenergic Receptor-Gs Protein Complex. Molecular Cell. 80: 3-5. PMID 33007256 DOI: 10.1016/j.molcel.2020.09.016   
2020 Pandey S, Saha S, Shukla AK. Transmitting the Signal: Structure of the β1-Adrenergic Receptor-Gs Protein Complex. Molecular Cell. 80: 3-5. PMID 33007256 DOI: 10.1016/j.molcel.2020.09.016   
2020 Pressly B, Lee RD, Barnych B, Hammock BD, Wulff H. Identification of the Functional Binding Site for the Convulsant Tetramethylenedisulfotetramine in the Pore of the α2β3γ2 GABA-A Receptor. Molecular Pharmacology. PMID 33109687 DOI: 10.1124/molpharm.120.000090   
2020 Castro MJ, Turani O, Faraoni MB, Gerbino D, Bouzat C. A New Antagonist of Glutamate-Activated Chloride Channels With Anthelmintic Activity. Frontiers in Neuroscience. 14: 879. PMID 32973433 DOI: 10.3389/fnins.2020.00879   
2020 Jakubík J, Randáková A, Chetverikov N, El-Fakahany EE, Doležal V. The operational model of allosteric modulation of pharmacological agonism. Scientific Reports. 10: 14421. PMID 32879329 DOI: 10.1038/s41598-020-71228-y   
2020 Gunera J, Baker JG, van Hilten N, Rosenbaum DM, Kolb P. Structure-Based Discovery of Novel Ligands for the Orexin 2 Receptor. Journal of Medicinal Chemistry. PMID 32977721 DOI: 10.1021/acs.jmedchem.0c00964   
2020 Boutin JA, Witt-Enderby PA, Sotriffer C, Zlotos DP. Melatonin receptor ligands: A pharmaco-chemical perspective. Journal of Pineal Research. 69: e12672. PMID 32531076 DOI: 10.1111/jpi.12672   
2020 Lemoine D, Mondoloni S, Tange J, Lambolez B, Faure P, Taly A, Tricoire L, Mourot A. Probing the ionotropic activity of glutamate GluD2 receptor in HEK cells with genetically-engineered photopharmacology. Elife. 9. PMID 33112237 DOI: 10.7554/eLife.59026   
2020 Chen J, Cai X, Yan M, Wang Z, Lv Z, Wang C. A method for identifying G protein-coupled receptor dimers and their interfaces. Biochimica Et Biophysica Acta. Molecular Cell Research. 118887. PMID 33075383 DOI: 10.1016/j.bbamcr.2020.118887   
2020 Harms M, Gilg A, Ständker L, Beer AJ, Mayer B, Rasche V, Gruber CW, Münch J. Microtiter plate-based antibody-competition assay to determine binding affinities and plasma/blood stability of CXCR4 ligands. Scientific Reports. 10: 16036. PMID 32994431 DOI: 10.1038/s41598-020-73012-4   
2020 Glaser T, Andrejew R, Oliveira-Giacomelli Á, Ribeiro DE, Bonfim Marques L, Ye Q, Ren WJ, Semyanov A, Illes P, Tang Y, Ulrich H. Purinergic Receptors in Basal Ganglia Diseases: Shared Molecular Mechanisms between Huntington's and Parkinson's Disease. Neuroscience Bulletin. PMID 33026587 DOI: 10.1007/s12264-020-00582-8   
2020 Kurtz R, Steinberg LG, Betcher M, Fowler D, Shepard BD. The Sensing Liver: Localization and Ligands for Hepatic Murine Olfactory and Taste Receptors. Frontiers in Physiology. 11: 574082. PMID 33123030 DOI: 10.3389/fphys.2020.574082   
2020 Haruta-Tsukamoto A, Miyahara Y, Funahashi H, Nishimori T, Ishida Y. Perampanel attenuates scratching behavior induced by acute or chronic pruritus in mice. Biochemical and Biophysical Research Communications. PMID 33028486 DOI: 10.1016/j.bbrc.2020.09.109   
2020 Bernhard M, Laube B. Thermophoretic analysis of ligand-specific conformational states of the inhibitory glycine receptor embedded in copolymer nanodiscs. Scientific Reports. 10: 16569. PMID 33024136 DOI: 10.1038/s41598-020-73157-2   
2020 Karra AG, Tziortziou M, Kylindri P, Georgatza D, Gorgogietas VA, Makiou A, Krokida A, Tsialtas I, Kalousi FD, Papadopoulos GE, Papadopoulou KΚ, Psarra AG. Boswellic acids and their derivatives as potent regulators of glucocorticoid receptor actions. Archives of Biochemistry and Biophysics. 695: 108656. PMID 33127380 DOI: 10.1016/j.abb.2020.108656   
2020 Borthwick AD, Goncalves MB, Corcoran JPT. Recent advances in the design of RAR α and RAR β agonists as orally bioavailable drugs. A review. Bioorganic & Medicinal Chemistry. 28: 115664. PMID 33069074 DOI: 10.1016/j.bmc.2020.115664   
2020 Zhang X, Peng K, Zhang X. The Function of the NMDA Receptor in Hypoxic-Ischemic Encephalopathy. Frontiers in Neuroscience. 14: 567665. PMID 33117117 DOI: 10.3389/fnins.2020.567665   
2020 Yang LK, Tao YX. Alanine Scanning Mutagenesis of the DRYxxI Motif and Intracellular Loop 2 of Human Melanocortin-4 Receptor. International Journal of Molecular Sciences. 21. PMID 33076233 DOI: 10.3390/ijms21207611   
2020 Fu TT, Tu G, Ping M, Zheng GX, Yang FY, Yang JY, Zhang Y, Yao XJ, Xue WW, Zhu F. Subtype-selective mechanisms of negative allosteric modulators binding to group I metabotropic glutamate receptors. Acta Pharmacologica Sinica. PMID 33122823 DOI: 10.1038/s41401-020-00541-z   
2020 Fernandes RA, Su L, Nishiga Y, Ren J, Bhuiyan AM, Cheng N, Kuo CJ, Picton LK, Ohtsuki S, Majzner RG, Rietberg SP, Mackall CL, Yin Q, Ali LR, Yang X, et al. Immune receptor inhibition through enforced phosphatase recruitment. Nature. PMID 33087934 DOI: 10.1038/s41586-020-2851-2   
2020 Lucianò AM, Tata AM. Functional Characterization of Cholinergic Receptors in Melanoma Cells. Cancers. 12. PMID 33120929 DOI: 10.3390/cancers12113141   
2020 Singh N, Villoutreix BO. Demystifying the Molecular Basis of Pyrazoloquinolinones Recognition at the Extracellular α1+/β3- Interface of the GABA Receptor by Molecular Modeling. Frontiers in Pharmacology. 11: 561834. PMID 33041802 DOI: 10.3389/fphar.2020.561834   
2020 Prabitha P, Shanmugarajan D, Kumar TDA, Kumar BRP. Multi-conformational frame from molecular dynamics as a structure-based pharmacophore model for mapping, screening and identifying ligands against PPAR-γ: a new protocol to develop promising candidates. Journal of Biomolecular Structure & Dynamics. 1-11. PMID 33140698 DOI: 10.1080/07391102.2020.1841677   
2020 Shim Y, Kim SY, Kim H, Hwang H, Chae JH, Choi J, Kim KJ, Yum MS, Ko TS, Kim YO, Byeon JH, Lee J, Lee J, Kim JS, Lim BC. Clinical outcomes of pediatric Anti-NMDA receptor encephalitis. European Journal of Paediatric Neurology : Ejpn : Official Journal of the European Paediatric Neurology Society. PMID 33046392 DOI: 10.1016/j.ejpn.2020.10.001   
2020 Symeonidis D, Lazaris A, Zizi Zerbetzoglou A, Christodoulou P, Kavantzas N, Tsavaris N, Thomopoulou GE. Correlation between LGR5 stem cells and location of tumor as well as age, sex and metastasis in colon adenocarcinoma. Journal of B.U.On. : Official Journal of the Balkan Union of Oncology. 25: 1827-1831. PMID 33099920   
2020 Haspula D, Clark MA. Cannabinoid Receptors: An Update on Cell Signaling, Pathophysiological Roles and Therapeutic Opportunities in Neurological, Cardiovascular, and Inflammatory Diseases. International Journal of Molecular Sciences. 21. PMID 33080916 DOI: 10.3390/ijms21207693   
2020 Paudel P, Shrestha S, Park SE, Seong SH, Fauzi FM, Jung HA, Choi JS. Emodin Derivatives as Multi-Target-Directed Ligands Inhibiting Monoamine Oxidase and Antagonizing Vasopressin V Receptors. Acs Omega. 5: 26720-26731. PMID 33110998 DOI: 10.1021/acsomega.0c03649   
2020 Ricart-Ortega M, Berizzi AE, Pereira V, Malhaire F, Catena J, Font J, Gómez-Santacana X, Muñoz L, Zussy C, Serra C, Rovira X, Goudet C, Llebaria A. Mechanistic Insights into Light-Driven Allosteric Control of GPCR Biological Activity. Acs Pharmacology & Translational Science. 3: 883-895. PMID 33073188 DOI: 10.1021/acsptsci.0c00054   
2020 Touma AM, Malik RU, Gupte T, Sivaramakrishnan S. Allosteric modulation of adenosine A1 and cannabinoid 1 receptor signaling by G-peptides. Pharmacology Research & Perspectives. 8: e00673. PMID 33124765 DOI: 10.1002/prp2.673   
2020 Kukkonen JP. Allosteric interactions via the orthosteric ligand binding sites in a constitutive G-protein-coupled receptor homodimer. Pharmacological Research. 105116. PMID 32783977 DOI: 10.1016/j.phrs.2020.105116   
2020 Illes P, Müller CE, Jacobson KA, Grutter T, Nicke A, Fountain SJ, Kennedy C, Schmalzing G, Jarvis MF, Stojilkovic SS, King BF, Di Virgilio F. Update of P2X receptor properties and their pharmacology: IUPHAR Review 30. British Journal of Pharmacology. PMID 33125712 DOI: 10.1111/bph.15299   
2020 Leung SW. The vascular impact of IP-TP receptor interactions. Acta Physiologica (Oxford, England). e13577. PMID 33135294 DOI: 10.1111/apha.13577   
2020 Pereira PMR, Mandleywala K, Ragupathi A, Lewis JS. Acute statin treatment improves antibody accumulation in EGFR- and PSMA-expressing tumors. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 32998959 DOI: 10.1158/1078-0432.CCR-20-1960   
2020 Xie XY, Li YY, Ma WH, Chen AF, Sun YT, Lee JY, Riad A, Xu DH, Mach RH, Huang YS. Synthesis, binding, and functional properties of tetrahydroisoquinolino-2-alkyl phenones as selective σR/TMEM97 ligands. European Journal of Medicinal Chemistry. 209: 112906. PMID 33049607 DOI: 10.1016/j.ejmech.2020.112906