Michel Lazdunski - Publications

Affiliations: 
IPMC CNRS, Paris, Île-de-France, France 

435 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Nicolas S, Zoukimian C, Bosmans F, Montnach J, Diochot S, Cuypers E, De Waard S, Béroud R, Mebs D, Craik D, Boturyn D, Lazdunski M, Tytgat J, De Waard M. Chemical Synthesis, Proper Folding, Na Channel Selectivity Profile and Analgesic Properties of the Spider Peptide Phlotoxin 1. Toxins. 11. PMID 31234412 DOI: 10.3390/Toxins11060367  0.431
2019 Attali B, Chandy KG, Giese MH, Grissmer S, Gutman GA, Jan LY, Lazdunski M, Mckinnon D, Nerbonne J, Pardo LA, Robertson GA, Rudy B, Sanguinetti MC, Stühmer W, Trimmer JS, et al. Voltage-gated potassium channels (version 2019.4) in the IUPHAR/BPS Guide to Pharmacology Database Iuphar/Bps Guide to Pharmacology Cite. 2019. DOI: 10.2218/gtopdb/f81/2019.4  0.43
2019 Adelman JP, Clapham DE, Hibino H, Inanobe A, Jan LY, Karschin A, Kubo Y, Kurachi Y, Lazdunski M, Miki T, Nichols CG, Palmer LG, Pearson WL, Sackin H, Seino S, et al. Inwardly rectifying potassium channels (version 2019.4) in the IUPHAR/BPS Guide to Pharmacology Database Iuphar/Bps Guide to Pharmacology Cite. 2019. DOI: 10.2218/gtopdb/f74/2019.4  0.442
2018 Poupon L, Lamoine S, Pereira V, Barriere DA, Lolignier S, Giraudet F, Aissouni Y, Meleine M, Prival L, Richard D, Kerckhove N, Authier N, Balayssac D, Eschalier A, Lazdunski M, et al. Targeting the TREK-1 potassium channel via riluzole to eliminate the neuropathic and depressive-like effects of oxaliplatin. Neuropharmacology. 140: 43-61. PMID 30056126 DOI: 10.1016/J.Neuropharm.2018.07.026  0.335
2015 Lingueglia E, Lazdunski M. Acid-Sensing Ion Channels in the nervous system. Foreword. Neuropharmacology. 94: 1. PMID 25813612 DOI: 10.1016/J.Neuropharm.2015.03.011  0.415
2014 Pereira V, Busserolles J, Christin M, Devilliers M, Poupon L, Legha W, Alloui A, Aissouni Y, Bourinet E, Lesage F, Eschalier A, Lazdunski M, Noël J. Role of the TREK2 potassium channel in cold and warm thermosensation and in pain perception. Pain. 155: 2534-44. PMID 25239074 DOI: 10.1016/J.Pain.2014.09.013  0.699
2013 Lingueglia E, Lazdunski M. Pharmacology of ASIC channels Wiley Interdisciplinary Reviews: Membrane Transport and Signaling. 2: 155-171. DOI: 10.1002/WMTS.88  0.396
2012 Diochot S, Baron A, Salinas M, Douguet D, Scarzello S, Dabert-Gay AS, Debayle D, Friend V, Alloui A, Lazdunski M, Lingueglia E. Black mamba venom peptides target acid-sensing ion channels to abolish pain. Nature. 490: 552-5. PMID 23034652 DOI: 10.1016/J.Toxicon.2013.08.022  0.385
2012 Maati HMO, Borsotto M, Chatelain F, Widmann C, Lazdunski M, Heurteaux C. Activation of ATP-sensitive potassium channels as an element of the neuroprotective effects of the Traditional Chinese Medicine MLC901 against oxygen glucose deprivation. Neuropharmacology. 63: 692-700. PMID 22659084 DOI: 10.1016/J.Neuropharm.2012.05.035  0.501
2011 Deval E, Noël J, Gasull X, Delaunay A, Alloui A, Friend V, Eschalier A, Lazdunski M, Lingueglia E. Acid-sensing ion channels in postoperative pain. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 6059-66. PMID 21508231 DOI: 10.1523/Jneurosci.5266-10.2011  0.385
2011 Descoeur J, Pereira V, Pizzoccaro A, Francois A, Ling B, Maffre V, Couette B, Busserolles J, Courteix C, Noel J, Lazdunski M, Eschalier A, Authier N, Bourinet E. Oxaliplatin-induced cold hypersensitivity is due to remodelling of ion channel expression in nociceptors. Embo Molecular Medicine. 3: 266-78. PMID 21438154 DOI: 10.1002/Emmm.201100134  0.434
2009 Salinas M, Lazdunski M, Lingueglia E. Structural elements for the generation of sustained currents by the acid pain sensor ASIC3 Journal of Biological Chemistry. 284: 31851-31859. PMID 19778905 DOI: 10.1074/Jbc.M109.043984  0.362
2009 Sandoz G, Douguet D, Chatelain F, Lazdunski M, Lesage F. Extracellular acidification exerts opposite actions on TREK1 and TREK2 potassium channels via a single conserved histidine residue. Proceedings of the National Academy of Sciences of the United States of America. 106: 14628-33. PMID 19667202 DOI: 10.1073/Pnas.0906267106  0.804
2009 Noël J, Zimmermann K, Busserolles J, Deval E, Alloui A, Diochot S, Guy N, Borsotto M, Reeh P, Eschalier A, Lazdunski M. The mechano-activated K± channels TRAAK and TREK-1 control both warm and cold perception Embo Journal. 28: 1308-1318. PMID 19279663 DOI: 10.1038/Emboj.2009.57  0.46
2009 Diochot S, Lazdunski M. Sea anemone toxins affecting potassium channels. Progress in Molecular and Subcellular Biology. 46: 99-122. PMID 19184586 DOI: 10.1007/978-3-540-87895-7_4  0.54
2009 Ettaiche M, Deval E, Pagnotta S, Lazdunski M, Lingueglia E. Acid-sensing ion channel 3 in retinal function and survival. Investigative Ophthalmology & Visual Science. 50: 2417-26. PMID 19117938 DOI: 10.1167/Iovs.08-3028  0.307
2008 Deval E, Noël J, Lay N, Alloui A, Diochot S, Friend V, Jodar M, Lazdunski M, Lingueglia E. ASIC3, a sensor of acidic and primary inflammatory pain Embo Journal. 27: 3047-3055. PMID 18923424 DOI: 10.1038/Emboj.2008.213  0.37
2008 Sandoz G, Tardy MP, Thümmler S, Feliciangeli S, Lazdunski M, Lesage F. Mtap2 is a constituent of the protein network that regulates twik-related K+ channel expression and trafficking. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 8545-52. PMID 18716213 DOI: 10.1523/Jneurosci.1962-08.2008  0.818
2008 Baron A, Voilley N, Lazdunski M, Lingueglia E. Acid sensing ion channels in dorsal spinal cord neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 1498-508. PMID 18256271 DOI: 10.1523/Jneurosci.4975-07.2008  0.361
2008 Wultsch T, Painsipp E, Shahbazian A, Mitrovic M, Edelsbrunner M, Lazdunski M, Waldmann R, Holzer P. Deletion of the acid-sensing ion channel ASIC3 prevents gastritis-induced acid hyperresponsiveness of the stomach-brainstem axis. Pain. 134: 245-53. PMID 17531389 DOI: 10.1016/J.Pain.2007.04.025  0.314
2007 Chemin J, Patel AJ, Delmas P, Sachs F, Lazdunski M, Honore E. Regulation of the Mechano-Gated K2P Channel TREK-1 by Membrane Phospholipids. Current Topics in Membranes. 59: 155-70. PMID 25168137 DOI: 10.1016/S1063-5823(06)59007-6  0.537
2007 Feliciangeli S, Bendahhou S, Sandoz G, Gounon P, Reichold M, Warth R, Lazdunski M, Barhanin J, Lesage F. Does Sumoylation Control K2P1/TWIK1 Background K+ Channels? Cell. 130: 563-569. PMID 17693262 DOI: 10.1016/J.Cell.2007.06.012  0.788
2007 Mazzuca M, Heurteaux C, Alloui A, Diochot S, Baron A, Voilley N, Blondeau N, Escoubas P, Gélot A, Cupo A, Zimmer A, Zimmer AM, Eschalier A, Lazdunski M. A tarantula peptide against pain via ASIC1a channels and opioid mechanisms. Nature Neuroscience. 10: 943-5. PMID 17632507 DOI: 10.1038/Nn1940  0.334
2007 Zhang M, Liu XS, Diochot S, Lazdunski M, Tseng GN. APETx1 from sea anemone Anthopleura elegantissima is a gating modifier peptide toxin of the human ether-a-go-go- related potassium channel. Molecular Pharmacology. 72: 259-68. PMID 17473056 DOI: 10.1124/Mol.107.035840  0.492
2007 Chemin J, Patel AJ, Duprat F, Sachs F, Lazdunski M, Honore E. Up- and down-regulation of the mechano-gated K(2P) channel TREK-1 by PIP (2) and other membrane phospholipids. Pflã¼Gers Archiv : European Journal of Physiology. 455: 97-103. PMID 17384962 DOI: 10.1007/S00424-007-0250-2  0.512
2007 Garry A, Fromy B, Blondeau N, Henrion D, Brau F, Gounon P, Guy N, Heurteaux C, Lazdunski M, Saumet JL. Altered acetylcholine, bradykinin and cutaneous pressure-induced vasodilation in mice lacking the TREK1 potassium channel: The endothelial link Embo Reports. 8: 354-359. PMID 17347672 DOI: 10.1038/Sj.Embor.7400916  0.452
2007 Thümmler S, Duprat F, Lazdunski M. Antipsychotics inhibit TREK but not TRAAK channels. Biochemical and Biophysical Research Communications. 354: 284-9. PMID 17222806 DOI: 10.1016/J.Bbrc.2006.12.199  0.463
2007 Diochot S, Salinas M, Baron A, Escoubas P, Lazdunski M. Peptides inhibitors of acid-sensing ion channels. Toxicon : Official Journal of the International Society On Toxinology. 49: 271-84. PMID 17113616 DOI: 10.1016/J.Toxicon.2006.09.026  0.522
2006 Sandoz G, Thümmler S, Duprat F, Feliciangeli S, Vinh J, Escoubas P, Guy N, Lazdunski M, Lesage F. AKAP150, a switch to convert mechano-, pH- and arachidonic acid-sensitive TREK K+ channels into open leak channels Embo Journal. 25: 5864-5872. PMID 17110924 DOI: 10.1038/Sj.Emboj.7601437  0.819
2006 Zanzouri M, Lauritzen I, Lazdunski M, Patel A. The background K(+) channel TASK-3 is regulated at both the transcriptional and post-transcriptional levels. Biochemical and Biophysical Research Communications. 348: 1350-7. PMID 16925981 DOI: 10.1016/J.Bbrc.2006.07.194  0.366
2006 Heurteaux C, Lucas G, Guy N, El Yacoubi M, Thümmler S, Peng XD, Noble F, Blondeau N, Widmann C, Borsotto M, Gobbi G, Vaugeois JM, Debonnel G, Lazdunski M. Deletion of the background potassium channel TREK-1 results in a depression-resistant phenotype. Nature Neuroscience. 9: 1134-41. PMID 16906152 DOI: 10.1038/Nn1749  0.367
2006 Zanzouri M, Lauritzen I, Duprat F, Mazzuca M, Lesage F, Lazdunski M, Patel A. Membrane potential-regulated transcription of the resting K+ conductance TASK-3 via the calcineurin pathway. The Journal of Biological Chemistry. 281: 28910-8. PMID 16864570 DOI: 10.1074/Jbc.M606092200  0.65
2006 Borsotto M, Cavarec L, Bouillot M, Romey G, Macciardi F, Delaye A, Nasroune M, Bastucci M, Sambucy JL, Luan JJ, Charpagne A, Jouët V, Léger R, Lazdunski M, Cohen D, et al. PP2A-Bgamma subunit and KCNQ2 K+ channels in bipolar disorder. The Pharmacogenomics Journal. 7: 123-32. PMID 16733521 DOI: 10.1038/Sj.Tpj.6500400  0.503
2006 Ettaiche M, Deval E, Cougnon M, Lazdunski M, Voilley N. Silencing acid-sensing ion channel 1a alters cone-mediated retinal function. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 5800-9. PMID 16723538 DOI: 10.1523/Jneurosci.0344-06.2006  0.351
2006 Alloui A, Zimmermann K, Mamet J, Duprat F, Noël J, Chemin J, Guy N, Blondeau N, Voilley N, Rubat-Coudert C, Borsotto M, Romey G, Heurteaux C, Reeh P, Eschalier A, ... Lazdunski M, et al. TREK-1, a K+ channel involved in polymodal pain perception Embo Journal. 25: 2368-2376. PMID 16675954 DOI: 10.1038/Sj.Emboj.7601116  0.409
2006 Lingueglia E, Deval E, Lazdunski M. FMRFamide-gated sodium channel and ASIC channels: a new class of ionotropic receptors for FMRFamide and related peptides. Peptides. 27: 1138-52. PMID 16516345 DOI: 10.1016/J.Peptides.2005.06.037  0.486
2006 Restano-Cassulini R, Korolkova YV, Diochot S, Gurrola G, Guasti L, Possani LD, Lazdunski M, Grishin EV, Arcangeli A, Wanke E. Species diversity and peptide toxins blocking selectivity of ether-a-go-go-related gene subfamily K+ channels in the central nervous system. Molecular Pharmacology. 69: 1673-83. PMID 16497878 DOI: 10.1124/Mol.105.019729  0.488
2006 Salinas M, Rash LD, Baron A, Lambeau G, Escoubas P, Lazdunski M. The receptor site of the spider toxin PcTx1 on the proton-gated cation channel ASIC1a. The Journal of Physiology. 570: 339-54. PMID 16284080 DOI: 10.1113/Jphysiol.2005.095810  0.452
2006 Bosmans F, Rash L, Zhu S, Diochot S, Lazdunski M, Escoubas P, Tytgat J. Four novel tarantula toxins as selective modulators of voltage-gated sodium channel subtypes. Molecular Pharmacology. 69: 419-29. PMID 16267209 DOI: 10.1124/Mol.105.015941  0.458
2006 Deval E, Friend V, Thirant C, Salinas M, Jodar M, Lazdunski M, Lingueglia E. Regulation of sensory neuron-specific acid-sensing ion channel 3 by the adaptor protein Na+/H+ exchanger regulatory factor-1. The Journal of Biological Chemistry. 281: 1796-807. PMID 16234233 DOI: 10.1074/Jbc.M509669200  0.513
2005 Kubo Y, Adelman JP, Clapham DE, Jan LY, Karschin A, Kurachi Y, Lazdunski M, Nichols CG, Seino S, Vandenberg CA. International Union of Pharmacology. LIV. Nomenclature and molecular relationships of inwardly rectifying potassium channels. Pharmacological Reviews. 57: 509-26. PMID 16382105 DOI: 10.1124/Pr.57.4.11  0.476
2005 Gutman GA, Chandy KG, Grissmer S, Lazdunski M, McKinnon D, Pardo LA, Robertson GA, Rudy B, Sanguinetti MC, Stühmer W, Wang X. International Union of Pharmacology. LIII. Nomenclature and molecular relationships of voltage-gated potassium channels. Pharmacological Reviews. 57: 473-508. PMID 16382104 DOI: 10.1124/pr.57.4.10  0.355
2005 Heurteaux C, Laigle C, Blondeau N, Jarretou G, Lazdunski M. Alpha-linolenic acid and riluzole treatment confer cerebral protection and improve survival after focal brain ischemia. Neuroscience. 137: 241-51. PMID 16289892 DOI: 10.1016/J.Neuroscience.2005.08.083  0.31
2005 Chagot B, Escoubas P, Diochot S, Bernard C, Lazdunski M, Darbon H. Solution structure of APETx2, a specific peptide inhibitor of ASIC3 proton-gated channels. Protein Science : a Publication of the Protein Society. 14: 2003-10. PMID 15987885 DOI: 10.1110/Ps.051378905  0.419
2005 Lauritzen I, Chemin J, Honoré E, Jodar M, Guy N, Lazdunski M, Patel AJ. Cross-talk between the mechano-gated K2P channel TREK-1 and the actin cytoskeleton Embo Reports. 6: 642-648. PMID 15976821 DOI: 10.1038/Sj.Embor.7400449  0.462
2005 Chagot B, Diochot S, Pimentel C, Lazdunski M, Darbon H. Solution structure of APETx1 from the sea anemone Anthopleura elegantissima: a new fold for an HERG toxin. Proteins. 59: 380-6. PMID 15726634 DOI: 10.1002/Prot.20425  0.366
2005 Chemin J, Patel AJ, Duprat F, Lauritzen I, Lazdunski M, Honoré E. A phospholipid sensor controls mechanogating of the K+ channel TREK-1. The Embo Journal. 24: 44-53. PMID 15577940 DOI: 10.1038/Sj.Emboj.7600494  0.504
2005 Chemin J, Patel A, Duprat F, Zanzouri M, Lazdunski M, Honoré E. Lysophosphatidic acid-operated K+ channels. The Journal of Biological Chemistry. 280: 4415-21. PMID 15572365 DOI: 10.1074/Jbc.M408246200  0.564
2005 Barhanin J, Attali B, Lazdunski M. IKs, a slow and intriguing cardiac K+ channel and its associated long QT diseases. Trends in Cardiovascular Medicine. 8: 207-14. PMID 14987566 DOI: 10.1016/S1050-1738(98)00013-9  0.508
2005 Heurteaux C, Laigle C, Jarretou G, Lazdunski M, Blondeau N. Alpha-linolenic acid and riluzole, activators of 2 pore-domain K+ channels afford brain protection against focal brain ischemia Journal of Cerebral Blood Flow & Metabolism. 25: S13-S13. DOI: 10.1038/Sj.Jcbfm.9591524.0013  0.418
2004 Decressac S, Franco M, Bendahhou S, Warth R, Knauer S, Barhanin J, Lazdunski M, Lesage F. ARF6-dependent interaction of the TWIK1 K+ channel with EFA6, a GDP/GTP exchange factor foe ARF6 Embo Reports. 5: 1171-1175. PMID 15540117 DOI: 10.1038/Sj.Embor.7400292  0.694
2004 Duprat F, Girard C, Jarretou G, Lazdunski M. Pancreatic two P domain K+ channels TALK-1 and TALK-2 are activated by nitric oxide and reactive oxygen species. The Journal of Physiology. 562: 235-44. PMID 15513946 DOI: 10.1113/Jphysiol.2004.071266  0.424
2004 Heurteaux C, Guy N, Laigle C, Blondeau N, Duprat F, Mazzuca M, Lang-Lazdunski L, Widmann C, Zanzouri M, Romey G, Lazdunski M. TREK-1, a K+ channel involved in neuroprotection and general anesthesia Embo Journal. 2684-2695. PMID 15175651 DOI: 10.1038/Sj.Emboj.7600234  0.394
2004 Roza C, Puel JL, Kress M, Baron A, Diochot S, Lazdunski M, Waldmann R. Knockout of the ASIC2 channel in mice does not impair cutaneous mechanosensation, visceral mechanonociception and hearing. The Journal of Physiology. 558: 659-69. PMID 15169849 DOI: 10.1113/Jphysiol.2004.066001  0.469
2004 Patel AJ, Lazdunski M. The 2P-domain K+ channels: role in apoptosis and tumorigenesis. Pflã¼Gers Archiv : European Journal of Physiology. 448: 261-73. PMID 15133669 DOI: 10.1007/S00424-004-1255-8  0.467
2004 Chagot B, Escoubas P, Villegas E, Bernard C, Ferrat G, Corzo G, Lazdunski M, Darbon H. Solution structure of Phrixotoxin 1, a specific peptide inhibitor of Kv4 potassium channels from the venom of the theraphosid spider Phrixotrichus auratus. Protein Science : a Publication of the Protein Society. 13: 1197-208. PMID 15096626 DOI: 10.1110/Ps.03584304  0.496
2004 Diochot S, Baron A, Rash LD, Deval E, Escoubas P, Scarzello S, Salinas M, Lazdunski M. A new sea anemone peptide, APETx2, inhibits ASIC3, a major acid-sensitive channel in sensory neurons. The Embo Journal. 23: 1516-25. PMID 15044953 DOI: 10.1038/Sj.Emboj.7600177  0.466
2004 Deval E, Salinas M, Baron A, Lingueglia E, Lazdunski M. ASIC2b-dependent regulation of ASIC3, an essential acid-sensing ion channel subunit in sensory neurons via the partner protein PICK-1. The Journal of Biological Chemistry. 279: 19531-9. PMID 14976185 DOI: 10.1074/Jbc.M313078200  0.441
2004 Ettaiche M, Guy N, Hofman P, Lazdunski M, Waldmann R. Acid-Sensing Ion Channel 2 Is Important for Retinal Function and Protects against Light-Induced Retinal Degeneration Journal of Neuroscience. 24: 1005-1012. PMID 14762118 DOI: 10.1523/Jneurosci.4698-03.2004  0.398
2003 Gutman GA, Chandy KG, Adelman JP, Aiyar J, Bayliss DA, Clapham DE, Covarriubias M, Desir GV, Furuichi K, Ganetzky B, Garcia ML, Grissmer S, Jan LY, Karschin A, Kim D, ... ... Lazdunski M, et al. International Union of Pharmacology. XLI. Compendium of voltage-gated ion channels: potassium channels. Pharmacological Reviews. 55: 583-6. PMID 14657415 DOI: 10.1124/Pr.55.4.9  0.692
2003 Chemin J, Girard C, Duprat F, Lesage F, Romey G, Lazdunski M. Mechanisms underlying excitatory effects of group I metabotropic glutamate receptors via inhibition of 2P domain K+ channels. The Embo Journal. 22: 5403-11. PMID 14532113 DOI: 10.1093/Emboj/Cdg528  0.704
2003 Mamet J, Lazdunski M, Voilley N. How nerve growth factor drives physiological and inflammatory expressions of acid-sensing ion channel 3 in sensory neurons. The Journal of Biological Chemistry. 278: 48907-13. PMID 14522957 DOI: 10.1074/Jbc.M309468200  0.389
2003 Rouault M, Bollinger JG, Lazdunski M, Gelb MH, Lambeau G. Novel mammalian group XII secreted phospholipase A2 lacking enzymatic activity. Biochemistry. 42: 11494-503. PMID 14516201 DOI: 10.1021/Bi0349930  0.315
2003 Escoubas P, Bernard C, Lambeau G, Lazdunski M, Darbon H. Recombinant production and solution structure of PcTx1, the specific peptide inhibitor of ASIC1a proton-gated cation channels. Protein Science : a Publication of the Protein Society. 12: 1332-43. PMID 12824480 DOI: 10.1110/Ps.0307003  0.47
2003 Magloire H, Lesage F, Couble ML, Lazdunski M, Bleicher F. Expression and localization of TREK-1 K+ channels in human odontoblasts. Journal of Dental Research. 82: 542-5. PMID 12821716 DOI: 10.1177/154405910308200711  0.688
2003 Diochot S, Loret E, Bruhn T, Béress L, Lazdunski M. APETx1, a new toxin from the sea anemone Anthopleura elegantissima, blocks voltage-gated human ether-a-go-go-related gene potassium channels. Molecular Pharmacology. 64: 59-69. PMID 12815161 DOI: 10.1124/Mol.64.1.59  0.498
2003 Lauritzen I, Zanzouri M, Honoré E, Duprat F, Ehrengruber MU, Lazdunski M, Patel AJ. K+-dependent cerebellar granule neuron apoptosis. Role of task leak K+ channels. The Journal of Biological Chemistry. 278: 32068-76. PMID 12783883 DOI: 10.1074/Jbc.M302631200  0.409
2003 Deval E, Baron A, Lingueglia E, Mazarguil H, Zajac JM, Lazdunski M. Effects of neuropeptide SF and related peptides on acid sensing ion channel 3 and sensory neuron excitability. Neuropharmacology. 44: 662-71. PMID 12668052 DOI: 10.1016/S0028-3908(03)00047-9  0.416
2002 Mamet J, Baron A, Lazdunski M, Voilley N. Proinflammatory mediators, stimulators of sensory neuron excitability via the expression of acid-sensing ion channels. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 22: 10662-70. PMID 12486159 DOI: 10.1523/Jneurosci.22-24-10662.2002  0.359
2002 Baron A, Deval E, Salinas M, Lingueglia E, Voilley N, Lazdunski M. Protein kinase C stimulates the acid-sensing ion channel ASIC2a via the PDZ domain-containing protein PICK1. The Journal of Biological Chemistry. 277: 50463-8. PMID 12399460 DOI: 10.1074/Jbc.M208848200  0.429
2002 Girard C, Tinel N, Terrenoire C, Romey G, Lazdunski M, Borsotto M. p11, an annexin II subunit, an auxiliary protein associated with the background K+ channel, TASK-1. The Embo Journal. 21: 4439-48. PMID 12198146 DOI: 10.1093/Emboj/Cdf469  0.486
2002 Blondeau N, Lauritzen I, Widmann C, Lazdunski M, Heurteaux C. A potent protective role of lysophospholipids against global cerebral ischemia and glutamate excitotoxicity in neuronal cultures. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 22: 821-34. PMID 12142567 DOI: 10.1097/00004647-200207000-00007  0.344
2002 Escoubas P, Diochot S, Célérier ML, Nakajima T, Lazdunski M. Novel tarantula toxins for subtypes of voltage-dependent potassium channels in the Kv2 and Kv4 subfamilies. Molecular Pharmacology. 62: 48-57. PMID 12065754 DOI: 10.1124/Mol.62.1.48  0.512
2002 Honoré E, Maingret F, Lazdunski M, Patel AJ. An intracellular proton sensor commands lipid- and mechano-gating of the K(+) channel TREK-1. The Embo Journal. 21: 2968-76. PMID 12065410 DOI: 10.1093/Emboj/Cdf288  0.456
2002 Maingret F, Honoré E, Lazdunski M, Patel AJ. Molecular basis of the voltage-dependent gating of TREK-1, a mechano-sensitive K(+) channel. Biochemical and Biophysical Research Communications. 292: 339-46. PMID 11906167 DOI: 10.1006/Bbrc.2002.6674  0.507
2002 DeCoster MA, Lambeau G, Lazdunski M, Bazan NG. Secreted phospholipase A2 potentiates glutamate-induced calcium increase and cell death in primary neuronal cultures. Journal of Neuroscience Research. 67: 634-45. PMID 11891776 DOI: 10.1002/Jnr.10131  0.322
2002 Baron A, Waldmann R, Lazdunski M. ASIC-like, proton-activated currents in rat hippocampal neurons. The Journal of Physiology. 539: 485-94. PMID 11882680 DOI: 10.1113/Jphysiol.2001.014837  0.491
2002 Anzai N, Deval E, Schaefer L, Friend V, Lazdunski M, Lingueglia E. The multivalent PDZ domain-containing protein CIPP is a partner of acid-sensing ion channel 3 in sensory neurons. The Journal of Biological Chemistry. 277: 16655-61. PMID 11872753 DOI: 10.1074/Jbc.M201087200  0.428
2001 Poët M, Tauc M, Lingueglia E, Cance P, Poujeol P, Lazdunski M, Counillon L. Exploration of the pore structure of a peptide-gated Na+ channel. The Embo Journal. 20: 5595-602. PMID 11598003 DOI: 10.1093/Emboj/20.20.5595  0.477
2001 Terrenoire C, Lauritzen I, Lesage F, Romey G, Lazdunski M. A TREK-1-like potassium channel in atrial cells inhibited by beta-adrenergic stimulation and activated by volatile anesthetics. Circulation Research. 89: 336-42. PMID 11509450 DOI: 10.1161/Hh1601.094979  0.69
2001 Baron A, Schaefer L, Lingueglia E, Champigny G, Lazdunski M. Zn2+ and H+ are coactivators of acid-sensing ion channels. The Journal of Biological Chemistry. 276: 35361-7. PMID 11457851 DOI: 10.1074/Jbc.M105208200  0.444
2001 Patel AJ, Lazdunski M, Honoré E. Lipid and mechano-gated 2P domain K(+) channels. Current Opinion in Cell Biology. 13: 422-8. PMID 11454447 DOI: 10.1016/S0955-0674(00)00231-3  0.511
2001 Girard C, Duprat F, Terrenoire C, Tinel N, Fosset M, Romey G, Lazdunski M, Lesage F. Genomic and functional characteristics of novel human pancreatic 2P domain K(+) channels. Biochemical and Biophysical Research Communications. 282: 249-56. PMID 11263999 DOI: 10.1006/Bbrc.2001.4562  0.689
2001 Maingret F, Patel AJ, Lazdunski M, Honoré E. The endocannabinoid anandamide is a direct and selective blocker of the background K(+) channel TASK-1. The Embo Journal. 20: 47-54. PMID 11226154 DOI: 10.1093/Emboj/20.1.47  0.438
2001 Ettaiche M, Heurteaux C, Blondeau N, Borsotto M, Tinel N, Lazdunski M. ATP-sensitive potassium channels (K(ATP)) in retina: a key role for delayed ischemic tolerance. Brain Research. 890: 118-29. PMID 11164774 DOI: 10.1016/S0006-8993(00)03152-8  0.471
2001 Tinel N, Diochot S, Borsotto M, Lazdunski M, Barhanin J. KCNE2 confers background current characteristics to the cardiac KCNQ1 potassium channel. The Embo Journal. 19: 6326-30. PMID 11101505 DOI: 10.1093/Emboj/19.23.6326  0.422
2001 Blondeau N, Plamondon H, Richelme C, Heurteaux C, Lazdunski M. K(ATP) channel openers, adenosine agonists and epileptic preconditioning are stress signals inducing hippocampal neuroprotection. Neuroscience. 100: 465-74. PMID 11098109 DOI: 10.1016/S0306-4522(00)00304-3  0.436
2001 Drici MD, Diochot S, Terrenoire C, Romey G, Lazdunski M. The bee venom peptide tertiapin underlines the role of I(KACh) in acetylcholine-induced atrioventricular blocks. British Journal of Pharmacology. 131: 569-77. PMID 11015309 DOI: 10.1038/Sj.Bjp.0703611  0.337
2001 Voilley N, de Weille J, Mamet J, Lazdunski M. Nonsteroid Anti-Inflammatory Drugs Inhibit Both the Activity and the Inflammation-Induced Expression of Acid-Sensing Ion Channels in Nociceptors The Journal of Neuroscience. 21: 8026-8033. DOI: 10.1523/Jneurosci.21-20-08026.2001  0.367
2001 Blondeau N, Widmann C, Lazdunski M, Heurteaux C. Activation of the Nuclear Factor-κB Is a Key Event in Brain Tolerance The Journal of Neuroscience. 21: 4668-4677. DOI: 10.1523/Jneurosci.21-13-04668.2001  0.304
2000 Lesage F, Lazdunski M. Molecular and functional properties of two-pore-domain potassium channels. American Journal of Physiology. Renal Physiology. 279: F793-801. PMID 11053038 DOI: 10.1152/Ajprenal.2000.279.5.F793  0.74
2000 Tinel N, Diochot S, Lauritzen I, Barhanin J, Lazdunski M, Borsotto M. M-type KCNQ2-KCNQ3 potassium channels are modulated by the KCNE2 subunit. Febs Letters. 480: 137-41. PMID 11034315 DOI: 10.1016/S0014-5793(00)01918-9  0.492
2000 Patel AJ, Maingret F, Magnone V, Fosset M, Lazdunski M, Honoré E. TWIK-2, an inactivating 2P domain K+ channel. The Journal of Biological Chemistry. 275: 28722-30. PMID 10887187 DOI: 10.1074/Jbc.M003755200  0.532
2000 Lesage F, Terrenoire C, Romey G, Lazdunski M. Human TREK2, a 2P domain mechano-sensitive K+ channel with multiple regulations by polyunsaturated fatty acids, lysophospholipids, and Gs, Gi, and Gq protein-coupled receptors. The Journal of Biological Chemistry. 275: 28398-405. PMID 10880510 DOI: 10.1074/Jbc.M002822200  0.719
2000 Maingret F, Lauritzen I, Patel AJ, Heurteaux C, Reyes R, Lesage F, Lazdunski M, Honoré E. TREK-1 is a heat-activated background K(+) channel. The Embo Journal. 19: 2483-91. PMID 10835347 DOI: 10.1093/Emboj/19.11.2483  0.702
2000 Escoubas P, De Weille JR, Lecoq A, Diochot S, Waldmann R, Champigny G, Moinier D, Ménez A, Lazdunski M. Isolation of a tarantula toxin specific for a class of proton-gated Na+ channels. The Journal of Biological Chemistry. 275: 25116-21. PMID 10829030 DOI: 10.1074/Jbc.M003643200  0.522
2000 Bearzatto B, Lesage F, Reyes R, Lazdunski M, Laduron PM. Axonal transport of TREK and TRAAK potassium channels in rat sciatic nerves. Neuroreport. 11: 927-30. PMID 10790857 DOI: 10.1097/00001756-200004070-00006  0.656
2000 Lauritzen I, Blondeau N, Heurteaux C, Widmann C, Romey G, Lazdunski M. Polyunsaturated fatty acids are potent neuroprotectors. The Embo Journal. 19: 1784-93. PMID 10775263 DOI: 10.1093/Emboj/19.8.1784  0.323
2000 Schaefer L, Sakai H, Mattei M, Lazdunski M, Lingueglia E. Molecular cloning, functional expression and chromosomal localization of an amiloride-sensitive Na(+) channel from human small intestine. Febs Letters. 471: 205-10. PMID 10767424 DOI: 10.1016/S0014-5793(00)01403-4  0.525
2000 Lesage F, Maingret F, Lazdunski M. Cloning and expression of human TRAAK, a polyunsaturated fatty acids-activated and mechano-sensitive K(+) channel. Febs Letters. 471: 137-40. PMID 10767409 DOI: 10.1016/S0014-5793(00)01388-0  0.699
2000 Maingret F, Patel AJ, Lesage F, Lazdunski M, Honoré E. Lysophospholipids open the two-pore domain mechano-gated K(+) channels TREK-1 and TRAAK. The Journal of Biological Chemistry. 275: 10128-33. PMID 10744694 DOI: 10.1074/Jbc.275.14.10128  0.634
2000 Reyes R, Lauritzen I, Lesage F, Ettaiche M, Fosset M, Lazdunski M. Immunolocalization of the arachidonic acid and mechanosensitive baseline traak potassium channel in the nervous system. Neuroscience. 95: 893-901. PMID 10670456 DOI: 10.1016/S0306-4522(99)00484-4  0.671
2000 Plamondon H, Blondeau N, Heurteaux C, Lazdunski M. Mutually protective actions of kainic acid epileptic preconditioning and sublethal global ischemia on hippocampal neuronal death: involvement of adenosine A1 receptors and K(ATP) channels. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 19: 1296-308. PMID 10598933 DOI: 10.1097/00004647-199912000-00002  0.346
2000 Lesage F, Patel A, Maingret F, Lauritzen I, Blondeau N, Reyes R, Heurteaux C, Romey G, Honore E, LAZDUNSKI M. 2P-DOMAIN K+ CHANNELS: STRUCTURE, PHYSIOLOGICAL FUNCTIONS, PHARMACOLOGY AND THERAPEUTIC IMPLICATIONS Biochemical Society Transactions. 28: A135-A135. DOI: 10.1042/Bst028A135C  0.686
1999 Schweitz H, Pacaud P, Diochot S, Moinier D, Lazdunski M. MIT(1), a black mamba toxin with a new and highly potent activity on intestinal contraction. Febs Letters. 461: 183-8. PMID 10567694 DOI: 10.1016/S0014-5793(99)01459-3  0.402
1999 Maingret F, Patel AJ, Lesage F, Lazdunski M, Honoré E. Mechano- or acid stimulation, two interactive modes of activation of the TREK-1 potassium channel. The Journal of Biological Chemistry. 274: 26691-6. PMID 10480871 DOI: 10.1074/Jbc.274.38.26691  0.691
1999 Sakai H, Lingueglia E, Champigny G, Mattei MG, Lazdunski M. Cloning and functional expression of a novel degenerin-like Na+ channel gene in mammals. The Journal of Physiology. 323-33. PMID 10457052 DOI: 10.1111/J.1469-7793.1999.0323M.X  0.53
1999 Patel AJ, Lazdunski M, Honoré E. Kv2.1/Kv9.3, an ATP-dependent delayed-rectifier K+ channel in pulmonary artery myocytes. Annals of the New York Academy of Sciences. 868: 438-41. PMID 10414317 DOI: 10.1111/J.1749-6632.1999.Tb11309.X  0.454
1999 Waldmann R, Champigny G, Lingueglia E, De Weille JR, Heurteaux C, Lazdunski M. H(+)-gated cation channels. Annals of the New York Academy of Sciences. 868: 67-76. PMID 10414282 DOI: 10.1111/J.1749-6632.1999.Tb11274.X  0.519
1999 Lambeau G, Lazdunski M. Receptors for a growing family of secreted phospholipases A2. Trends in Pharmacological Sciences. 20: 162-70. PMID 10322502 DOI: 10.1016/S0165-6147(99)01300-0  0.302
1999 Patel AJ, Honoré E, Lesage F, Fink M, Romey G, Lazdunski M. Inhalational anesthetics activate two-pore-domain background K+ channels. Nature Neuroscience. 2: 422-6. PMID 10321245 DOI: 10.1038/8084  0.69
1999 Salinas M, Reyes R, Lesage F, Fosset M, Heurteaux C, Romey G, Lazdunski M. Cloning of a new mouse two-P domain channel subunit and a human homologue with a unique pore structure. The Journal of Biological Chemistry. 274: 11751-60. PMID 10206991 DOI: 10.1074/Jbc.274.17.11751  0.718
1999 Coscoy S, de Weille JR, Lingueglia E, Lazdunski M. The pre-transmembrane 1 domain of acid-sensing ion channels participates in the ion pore. The Journal of Biological Chemistry. 274: 10129-32. PMID 10187795 DOI: 10.1074/Jbc.274.15.10129  0.498
1999 Diochot S, Drici MD, Moinier D, Fink M, Lazdunski M. Effects of phrixotoxins on the Kv4 family of potassium channels and implications for the role of Ito1 in cardiac electrogenesis. British Journal of Pharmacology. 126: 251-63. PMID 10051143 DOI: 10.1038/Sj.Bjp.0702283  0.456
1999 Maingret F, Fosset M, Lesage F, Lazdunski M, Honoré E. TRAAK is a mammalian neuronal mechano-gated K+ channel. The Journal of Biological Chemistry. 274: 1381-7. PMID 9880510 DOI: 10.1074/Jbc.274.3.1381  0.703
1999 Cluzeaud F, Reyes R, Escoubet B, Fay M, Lazdunski M, Bonvalet JP, Lesage F, Farman N. Expression of TWIK-1, a novel weakly inward rectifying potassium channel in rat kidney. The American Journal of Physiology. 275: C1602-9. PMID 9843722 DOI: 10.1152/Ajpcell.1998.275.6.C1602  0.709
1999 Lesage F, Lazdunski M. Chapter 12 Potassium Channels with Two P Domains Current Topics in Membranes. 46: 199-222. DOI: 10.1016/S0070-2161(08)60928-4  0.728
1999 Barhanin J, Romey G, Lazdunski M. Chapter 5 IsK: A Novel Type of Potassium Channel Regulatory Subunit Current Topics in Membranes. 46: 67-84. DOI: 10.1016/S0070-2161(08)60921-1  0.5
1998 Tinel N, Lauritzen I, Chouabe C, Lazdunski M, Borsotto M. The KCNQ2 potassium channel: splice variants, functional and developmental expression. Brain localization and comparison with KCNQ3. Febs Letters. 438: 171-6. PMID 9827540 DOI: 10.1016/S0014-5793(98)01296-4  0.457
1998 Reyes R, Duprat F, Lesage F, Fink M, Salinas M, Farman N, Lazdunski M. Cloning and expression of a novel pH-sensitive two pore domain K+ channel from human kidney. The Journal of Biological Chemistry. 273: 30863-9. PMID 9812978 DOI: 10.1074/Jbc.273.47.30863  0.678
1998 de Weille JR, Bassilana F, Lazdunski M, Waldmann R. Identification, functional expression and chromosomal localisation of a sustained human proton-gated cation channel. Febs Letters. 433: 257-60. PMID 9744806 DOI: 10.1016/S0014-5793(98)00916-8  0.448
1998 Lesage F, Lazdunski M. Mapping of human potassium channel genes TREK-1 (KCNK2) and TASK (KCNK3) to chromosomes 1q41 and 2p23. Genomics. 51: 478-9. PMID 9721223 DOI: 10.1006/Geno.1998.5397  0.613
1998 Patel AJ, Honoré E, Maingret F, Lesage F, Fink M, Duprat F, Lazdunski M. A mammalian two pore domain mechano-gated S-like K+ channel. The Embo Journal. 17: 4283-90. PMID 9687497 DOI: 10.1093/Emboj/17.15.4283  0.73
1998 Waldmann R, Lazdunski M. H(+)-gated cation channels: neuronal acid sensors in the NaC/DEG family of ion channels. Current Opinion in Neurobiology. 8: 418-24. PMID 9687356 DOI: 10.1016/S0959-4388(98)80070-6  0.503
1998 Persu A, Barbry P, Bassilana F, Houot AM, Mengual R, Lazdunski M, Corvol P, Jeunemaitre X. Genetic analysis of the beta subunit of the epithelial Na+ channel in essential hypertension. Hypertension (Dallas, Tex. : 1979). 32: 129-37. PMID 9674649 DOI: 10.1161/01.Hyp.32.1.129  0.339
1998 Fink M, Lesage F, Duprat F, Heurteaux C, Reyes R, Fosset M, Lazdunski M. A neuronal two P domain K+ channel stimulated by arachidonic acid and polyunsaturated fatty acids. The Embo Journal. 17: 3297-308. PMID 9628867 DOI: 10.1093/Emboj/17.12.3297  0.717
1998 Champigny G, Voilley N, Waldmann R, Lazdunski M. Mutations causing neurodegeneration in Caenorhabditis elegans drastically alter the pH sensitivity and inactivation of the mammalian H+-gated Na+ channel MDEG1. The Journal of Biological Chemistry. 273: 15418-22. PMID 9624125 DOI: 10.1074/Jbc.273.25.15418  0.493
1998 Darboux I, Lingueglia E, Pauron D, Barbry P, Lazdunski M. A new member of the amiloride-sensitive sodium channel family in Drosophila melanogaster peripheral nervous system. Biochemical and Biophysical Research Communications. 246: 210-6. PMID 9600094 DOI: 10.1006/Bbrc.1998.8183  0.489
1998 Darboux I, Lingueglia E, Champigny G, Coscoy S, Barbry P, Lazdunski M. dGNaC1, a gonad-specific amiloride-sensitive Na+ channel. The Journal of Biological Chemistry. 273: 9424-9. PMID 9545267 DOI: 10.1074/Jbc.273.16.9424  0.522
1998 Coscoy S, Lingueglia E, Lazdunski M, Barbry P. The Phe-Met-Arg-Phe-amide-activated sodium channel is a tetramer. The Journal of Biological Chemistry. 273: 8317-22. PMID 9525939 DOI: 10.1074/Jbc.273.14.8317  0.522
1998 Diochot S, Schweitz H, Béress L, Lazdunski M. Sea anemone peptides with a specific blocking activity against the fast inactivating potassium channel Kv3.4. The Journal of Biological Chemistry. 273: 6744-9. PMID 9506974 DOI: 10.1074/JBC.273.12.6744  0.472
1998 Voilley N, Galibert A, Bassilana F, Renard S, Lingueglia E, Coscoy S, Champigny G, Hofman P, Lazdunski M, Barbry P. The amiloride-sensitive Na+ channel: from primary structure to function. Comparative Biochemistry and Physiology. Part a, Physiology. 118: 193-200. PMID 9366043 DOI: 10.1016/S0300-9629(97)00066-2  0.459
1998 Patel AJ, Lauritzen I, Lazdunski M, Honoré E. Disruption of Mitochondrial Respiration Inhibits Volume-Regulated Anion Channels and Provokes Neuronal Cell Swelling The Journal of Neuroscience. 18: 3117-3123. DOI: 10.1523/Jneurosci.18-09-03117.1998  0.383
1997 Lingueglia E, de Weille JR, Bassilana F, Heurteaux C, Sakai H, Waldmann R, Lazdunski M. A modulatory subunit of acid sensing ion channels in brain and dorsal root ganglion cells. The Journal of Biological Chemistry. 272: 29778-83. PMID 9368048 DOI: 10.1074/Jbc.272.47.29778  0.522
1997 Patel AJ, Lazdunski M, Honoré E. Kv2.1/Kv9.3, a novel ATP-dependent delayed-rectifier K+ channel in oxygen-sensitive pulmonary artery myocytes. The Embo Journal. 16: 6615-25. PMID 9362476 DOI: 10.1093/Emboj/16.22.6615  0.476
1997 Bassilana F, Champigny G, Waldmann R, de Weille JR, Heurteaux C, Lazdunski M. The acid-sensitive ionic channel subunit ASIC and the mammalian degenerin MDEG form a heteromultimeric H+-gated Na+ channel with novel properties. The Journal of Biological Chemistry. 272: 28819-22. PMID 9360943 DOI: 10.1074/Jbc.272.46.28819  0.523
1997 Lauritzen I, De Weille JR, Lazdunski M. The potassium channel opener (-)-cromakalim prevents glutamate-induced cell death in hippocampal neurons. Journal of Neurochemistry. 69: 1570-9. PMID 9326286 DOI: 10.1046/J.1471-4159.1997.69041570.X  0.392
1997 Chouabe C, Neyroud N, Guicheney P, Lazdunski M, Romey G, Barhanin J. Properties of KvLQT1 K+ channel mutations in Romano-Ward and Jervell and Lange-Nielsen inherited cardiac arrhythmias. The Embo Journal. 16: 5472-9. PMID 9312006 DOI: 10.1093/Emboj/16.17.5472  0.464
1997 Duprat F, Lesage F, Fink M, Reyes R, Heurteaux C, Lazdunski M. TASK, a human background K+ channel to sense external pH variations near physiological pH. The Embo Journal. 16: 5464-71. PMID 9312005 DOI: 10.1093/Emboj/16.17.5464  0.664
1997 Salinas M, Duprat F, Heurteaux C, Hugnot JP, Lazdunski M. New modulatory alpha subunits for mammalian Shab K+ channels. The Journal of Biological Chemistry. 272: 24371-9. PMID 9305895 DOI: 10.1074/Jbc.272.39.24371  0.486
1997 Murer G, Adelbrecht C, Lauritzen I, Lesage F, Lazdunski M, Agid Y, Raisman-Vozari R. An immunocytochemical study on the distribution of two G-protein-gated inward rectifier potassium channels (GIRK2 and GIRK4) in the adult rat brain. Neuroscience. 80: 345-57. PMID 9284339 DOI: 10.1016/S0306-4522(97)00001-8  0.672
1997 Mourre C, Lazdunski M, Jarrard LE. Behaviors and neurodegeneration induced by two blockers of K+ channels, the mast cell degranulating peptide and Dendrotoxin I. Brain Research. 762: 223-7. PMID 9262178 DOI: 10.1016/S0006-8993(97)00481-2  0.433
1997 Waldmann R, Bassilana F, de Weille J, Champigny G, Heurteaux C, Lazdunski M. Molecular cloning of a non-inactivating proton-gated Na+ channel specific for sensory neurons. The Journal of Biological Chemistry. 272: 20975-8. PMID 9261094 DOI: 10.1074/Jbc.272.34.20975  0.494
1997 Romey G, Attali B, Chouabe C, Abitbol I, Guillemare E, Barhanin J, Lazdunski M. Molecular mechanism and functional significance of the MinK control of the KvLQT1 channel activity. The Journal of Biological Chemistry. 272: 16713-6. PMID 9201970 DOI: 10.1074/Jbc.272.27.16713  0.449
1997 Lauritzen I, De Weille J, Adelbrecht C, Lesage F, Murer G, Raisman-Vozari R, Lazdunski M. Comparative expression of the inward rectifier K+ channel GIRK2 in the cerebellum of normal and weaver mutant mice. Brain Research. 753: 8-17. PMID 9125426 DOI: 10.1016/S0006-8993(96)01491-6  0.628
1997 Salinas M, Weille Jd, Guillemare E, Lazdunski M, Hugnot J. Modes of regulation of shab K^+ channel activity by the Kv8.1 subunit Journal of Biological Chemistry. 272: 8774-8780. PMID 9079713 DOI: 10.1074/Jbc.272.13.8774  0.538
1997 Waldmann R, Champigny G, Bassilana F, Heurteaux C, Lazdunski M. A proton-gated cation channel involved in acid-sensing. Nature. 386: 173-7. PMID 9062189 DOI: 10.1038/386173A0  0.53
1997 Nicolas JP, Lin Y, Lambeau G, Ghomashchi F, Lazdunski M, Gelb MH. Localization of structural elements of bee venom phospholipase A2 involved in N-type receptor binding and neurotoxicity. The Journal of Biological Chemistry. 272: 7173-81. PMID 9054413 DOI: 10.1074/Jbc.272.11.7173  0.339
1997 Hugnot JP, Pedeutour F, Le Calvez C, Grosgeorge J, Passage E, Fontes M, Lazdunski M. The human inward rectifying K+ channel Kir 2.2 (KCNJ12) gene: gene structure, assignment to chromosome 17p11.1, and identification of a simple tandem repeat polymorphism. Genomics. 39: 113-6. PMID 9027495 DOI: 10.1006/Geno.1996.4450  0.466
1997 Lesage F, Lauritzen I, Duprat F, Reyes R, Fink M, Heurteaux C, Lazdunski M. The structure, function and distribution of the mouse TWIK-1 K+ channel. Febs Letters. 402: 28-32. PMID 9013852 DOI: 10.1016/S0014-5793(96)01491-3  0.674
1997 Lazdunski M. Ion channel effects of antidiabetic sulfonylureas. Hormone and Metabolic Research = Hormon- Und Stoffwechselforschung = Hormones Et Metabolisme. 28: 488-95. PMID 8911986 DOI: 10.1055/S-2007-979840  0.379
1997 Gandolfo G, Lambeau G, Lazdunski M, Gottesmann C. Effects on behaviour and EEG of single chain phospholipases A2 from snake and bee venoms injected into rat brain: search for a functional antagonism. Pharmacology & Toxicology. 78: 341-7. PMID 8737971 DOI: 10.1111/J.1600-0773.1996.Tb01386.X  0.379
1997 Waldmann R, Bassilana F, Voilley N, Lazdunski M, Mattéi M. Assignment of the human amiloride-sensitive Na+ channel delta isoform to chromosome 1p36.3-p36.2. Genomics. 34: 262-3. PMID 8661065 DOI: 10.1006/Geno.1996.0282  0.417
1996 Vetter DE, Mann JR, Wangemann P, Liu J, McLaughlin KJ, Lesage F, Marcus DC, Lazdunski M, Heinemann SF, Barhanin J. Inner ear defects induced by null mutation of the isk gene. Neuron. 17: 1251-64. PMID 8982171 DOI: 10.1016/S0896-6273(00)80255-X  0.569
1996 Barhanin J, Lesage F, Guillemare E, Fink M, Lazdunski M, Romey G. K(V)LQT1 and lsK (minK) proteins associate to form the I(Ks) cardiac potassium current. Nature. 384: 78-80. PMID 8900282 DOI: 10.1038/384078A0  0.689
1996 Fink M, Duprat F, Lesage F, Heurteaux C, Romey G, Barhanin J, Lazdunski M. A new K+ channel beta subunit to specifically enhance Kv2.2 (CDRK) expression. The Journal of Biological Chemistry. 271: 26341-8. PMID 8824288 DOI: 10.1074/Jbc.271.42.26341  0.712
1996 Barbry P, Lazdunski M. Structure and regulation of the amiloride-sensitive epithelial sodium channel. Ion Channels. 4: 115-67. PMID 8744208 DOI: 10.1007/978-1-4899-1775-1_4  0.364
1996 Lingueglia E, Voilley N, Lazdunski M, Barbry P. Molecular biology of the amiloride-sensitive epithelial Na+ channel. Experimental Physiology. 81: 483-92. PMID 8737081 DOI: 10.1113/expphysiol.1996.sp003951  0.39
1996 Lesage F, Mattéi M, Fink M, Barhanin J, Lazdunski M. Assignment of the human weak inward rectifier K+ channel TWIK-1 gene to chromosome 1q42-q43. Genomics. 34: 153-5. PMID 8661042 DOI: 10.1006/Geno.1996.0259  0.629
1996 Waldmann R, Champigny G, Voilley N, Lauritzen I, Lazdunski M. The mammalian degenerin MDEG, an amiloride-sensitive cation channel activated by mutations causing neurodegeneration in Caenorhabditis elegans. The Journal of Biological Chemistry. 271: 10433-6. PMID 8631835 DOI: 10.1074/Jbc.271.18.10433  0.475
1996 Lesage F, Guillemare E, Fink M, Duprat F, Lazdunski M, Romey G, Barhanin J. A pH-sensitive yeast outward rectifier K+ channel with two pore domains and novel gating properties. The Journal of Biological Chemistry. 271: 4183-7. PMID 8626760 DOI: 10.1074/Jbc.271.8.4183  0.728
1996 Fosset M, Allard B, Lazdunski M. Coexistence of two classes of glibenclamide-inhibitable ATP-regulated K+ channels in avian skeletal muscle. Pflugers Archiv : European Journal of Physiology. 431: 117-24. PMID 8584408 DOI: 10.1007/Bf00374384  0.483
1996 Lesage F, Fink M, Barhanin J, Lazdunski M, Mattéi MG. Assignment of human G-protein-coupled inward rectifier K+ channel homolog GIRK3 gene to chromosome 1q21-q23. Genomics. 29: 808-9. PMID 8575783 DOI: 10.1006/Geno.1995.9928  0.699
1996 Fink M, Duprat F, Heurteaux C, Lesage F, Romey G, Barhanin J, Lazdunski M. Dominant negative chimeras provide evidence for homo and heteromultimeric assembly of inward rectifier K+ channel proteins via their N-terminal end. Febs Letters. 378: 64-8. PMID 8549804 DOI: 10.1016/0014-5793(95)01388-1  0.704
1996 Duprat F, Guillemare E, Romey G, Fink M, Lesage F, Lazdunski M, Honore E. Susceptibility of cloned K+ channels to reactive oxygen species. Proceedings of the National Academy of Sciences of the United States of America. 92: 11796-800. PMID 8524851 DOI: 10.1073/Pnas.92.25.11796  0.717
1996 Lingueglia E, Champigny G, Lazdunski M, Barbry P. Cloning of the amiloride-sensitive FMRFamide peptide-gated sodium channel. Nature. 378: 730-3. PMID 7501021 DOI: 10.1038/378730A0  0.454
1996 Lesage F, Guillemare E, Fink M, Duprat F, Heurteaux C, Fosset M, Romey G, Barhanin J, Lazdunski M. Molecular properties of neuronal G-protein-activated inwardly rectifying K+ channels. The Journal of Biological Chemistry. 270: 28660-7. PMID 7499385 DOI: 10.1074/Jbc.270.48.28660  0.732
1996 Waldmann R, Champigny G, Bassilana F, Voilley N, Lazdunski M. Molecular cloning and functional expression of a novel amiloride-sensitive Na+ channel. The Journal of Biological Chemistry. 270: 27411-4. PMID 7499195 DOI: 10.1074/Jbc.270.46.27411  0.503
1996 Renard S, Voilley N, Bassilana F, Lazdunski M, Barbry P. Localization and regulation by steroids of the alpha, beta and gamma subunits of the amiloride-sensitive Na+ channel in colon, lung and kidney. Pflugers Archiv : European Journal of Physiology. 430: 299-307. PMID 7491252 DOI: 10.1007/Bf00373903  0.387
1996 Schweitz H, Bruhn T, Guillemare E, Moinier D, Lancelin J, Beress L, Lazdunski M. Kalicludines and kaliseptine: Two different classes of sea anemone toxins for voltage-sensitive K+ channels Toxicon. 34: 1095. DOI: 10.1016/0041-0101(96)83832-3  0.502
1996 Fink M, Duprat F, Lesage F, Reyes R, Romey G, Heurteaux C, Lazdunski M. Cloning, functional expression and brain localization of a novel unconventional outward rectifier K+ channel. The Embo Journal. 15: 6854-6862. DOI: 10.1002/J.1460-2075.1996.Tb01077.X  0.728
1996 Lesage F, Reyes R, Fink M, Duprat F, Guillemare E, Lazdunski M. Dimerization of TWIK-1 K+ channel subunits via a disulfide bridge. The Embo Journal. 15: 6400-6407. DOI: 10.1002/J.1460-2075.1996.Tb01031.X  0.708
1996 Hugnot JP, Salinas M, Lesage F, Guillemare E, de Weille J, Heurteaux C, Mattéi MG, Lazdunski M. Kv8.1, a new neuronal potassium channel subunit with specific inhibitory properties towards Shab and Shaw channels. The Embo Journal. 15: 3322-3331. DOI: 10.1002/J.1460-2075.1996.Tb00697.X  0.721
1996 Lesage F, Guillemare E, Fink M, Duprat F, Lazdunski M, Romey G, Barhanin J. TWIK-1, a ubiquitous human weakly inward rectifying K+ channel with a novel structure. The Embo Journal. 15: 1004-1011. DOI: 10.1002/J.1460-2075.1996.Tb00437.X  0.732
1995 Fossier P, Lambeau G, Lazdunski M, Baux G. Inhibition of ACh release at an Aplysia synapse by neurotoxic phospholipases A2: Specific receptors and mechanisms of action Journal of Physiology. 489: 29-40. PMID 8583413 DOI: 10.1113/Jphysiol.1995.Sp021027  0.35
1995 Romey G, Bois P, Lazdunski M. Effects of two chemically related new Ca2+ channel antagonists, SR33557 (fantofarone) and SR33805, on the L-type cardiac channel. European Journal of Pharmacology. 263: 101-5. PMID 7821341 DOI: 10.1016/0014-2999(94)90529-0  0.441
1995 Honoré E, Lazdunski M. Biophysical, pharmacological and developmental properties of ATP-sensitive K+ channels in cultured myotomal muscle cells from Xenopus embryos. Pflugers Archiv : European Journal of Physiology. 429: 607-16. PMID 7792138 DOI: 10.1007/Bf00373981  0.548
1995 Heurteaux C, Lauritzen I, Widmann C, Lazdunski M. Essential role of adenosine, adenosine A1 receptors, and ATP-sensitive K+ channels in cerebral ischemic preconditioning. Proceedings of the National Academy of Sciences of the United States of America. 92: 4666-70. PMID 7753861 DOI: 10.1073/Pnas.92.10.4666  0.429
1995 Waldmann R, Champigny G, Lazdunski M. Functional degenerin-containing chimeras identify residues essential for amiloride-sensitive Na+ channel function. The Journal of Biological Chemistry. 270: 11735-7. PMID 7744818 DOI: 10.1074/Jbc.270.20.11735  0.505
1995 Van Renterghem C, Lazdunski M. Identification of the Ca2+ current activated by vasoconstrictors in vascular smooth muscle cells. Pflugers Archiv : European Journal of Physiology. 429: 1-6. PMID 7708469 DOI: 10.1007/Bf02584023  0.346
1995 Allard B, Lazdunski M, Rougier O. Activation of ATP-dependent K+ channels by metabolic poisoning in adult mouse skeletal muscle: role of intracellular Mg(2+) and pH. The Journal of Physiology. 283-96. PMID 7666359 DOI: 10.1113/Jphysiol.1995.Sp020730  0.545
1995 Duprat F, Lesage F, Guillemare E, Fink M, Hugnot JP, Bigay J, Lazdunski M, Romey G, Barhanin J. Heterologous multimeric assembly is essential for K+ channel activity of neuronal and cardiac G-protein-activated inward rectifiers. Biochemical and Biophysical Research Communications. 212: 657-63. PMID 7626080 DOI: 10.1006/Bbrc.1995.2019  0.723
1995 Schweitz H, Bruhn T, Guillemare E, Moinier D, Lancelin JM, Béress L, Lazdunski M. Kalicludines and kaliseptine. Two different classes of sea anemone toxins for voltage sensitive K+ channels. The Journal of Biological Chemistry. 270: 25121-6. PMID 7559645 DOI: 10.1074/Jbc.270.42.25121  0.524
1995 Champigny G, Imler JL, Puchelle E, Dalemans W, Gribkoff V, Hinnrasky J, Dott K, Barbry P, Pavirani A, Lazdunski M. A change in gating mode leading to increased intrinsic CI- channel activity compensates for defective processing in a cystic fibrosis mutant corresponding to a mild form of the disease Embo Journal. 14: 2417-2423. PMID 7540133 DOI: 10.1002/J.1460-2075.1995.Tb07239.X  0.354
1995 Guillemare E, Lazdunski M, Honoré E. CGRP-induced activation of KATP channels in follicular Xenopus oocytes. Pflugers Archiv : European Journal of Physiology. 428: 604-9. PMID 7530840 DOI: 10.1007/Bf00374584  0.53
1995 Voilley N, Bassilana F, Mignon C, Merscher S, Mattéi MG, Carle GF, Lazdunski M, Barbry P. Cloning, chromosomal localization, and physical linkage of the beta and gamma subunits (SCNN1B and SCNN1G) of the human epithelial amiloride-sensitive sodium channel. Genomics. 28: 560-5. PMID 7490094 DOI: 10.1006/Geno.1995.1188  0.324
1995 Lancelin J, Foray M, Hollecker M, Schweitz H, Romey G, Lazdunski M. Peptidic toxins homologous to the Kunitz inhibitor in the African mamba snake venoms of the Dendroaspis genus: a versatile molecular architecture for the blocking of neuronal ionic channels Toxicon. 33: 1126. DOI: 10.1016/0041-0101(95)93848-O  0.401
1994 Coppola T, Waldmann R, Borsotto M, Heurteaux C, Romey G, Mattéi MG, Lazdunski M. Molecular cloning of a murine N-type calcium channel alpha 1 subunit. Evidence for isoforms, brain distribution, and chromosomal localization. Febs Letters. 338: 1-5. PMID 8307146 DOI: 10.1016/0014-5793(94)80105-3  0.404
1994 Schweitz H, Heurteaux C, Bois P, Moinier D, Romey G, Lazdunski M. Calcicludine, a venom peptide of the Kunitz-type protease inhibitor family, is a potent blocker of high-threshold Ca2+ channels with a high affinity for L-type channels in cerebellar granule neurons. Proceedings of the National Academy of Sciences of the United States of America. 91: 878-82. PMID 8302860 DOI: 10.1073/Pnas.91.3.878  0.461
1994 Voilley N, Lingueglia E, Champigny G, Mattéi MG, Waldmann R, Lazdunski M, Barbry P. The lung amiloride-sensitive Na+ channel: biophysical properties, pharmacology, ontogenesis, and molecular cloning. Proceedings of the National Academy of Sciences of the United States of America. 91: 247-51. PMID 8278374 DOI: 10.1073/PNAS.91.1.247  0.402
1994 Van Renterghem C, Lazdunski M. Endothelin and vasopressin activate low conductance chloride channels in aortic smooth muscle cells. Pflugers Archiv : European Journal of Physiology. 425: 156-63. PMID 8272371 DOI: 10.1007/BF00374516  0.42
1994 Honoré E, Barhanin J, Attali B, Lesage F, Lazdunski M. External blockade of the major cardiac delayed-rectifier K+ channel (Kv1.5) by polyunsaturated fatty acids. Proceedings of the National Academy of Sciences of the United States of America. 91: 1937-41. PMID 8127910 DOI: 10.1073/Pnas.91.5.1937  0.679
1994 Lesage F, Hugnot JP, Amri EZ, Grimaldi P, Barhanin J, Lazdunski M. Expression cloning in K+ transport defective yeast and distribution of HBP1, a new putative HMG transcriptional regulator. Nucleic Acids Research. 22: 3685-8. PMID 7937077 DOI: 10.1093/Nar/22.18.3685  0.646
1994 Lesage F, Duprat F, Fink M, Guillemare E, Coppola T, Lazdunski M, Hugnot JP. Cloning provides evidence for a family of inward rectifier and G-protein coupled K+ channels in the brain. Febs Letters. 353: 37-42. PMID 7926018 DOI: 10.1016/0014-5793(94)01007-2  0.703
1994 Honoré E, Guillemare E, Lesage F, Barhanin J, Lazdunski M. Injection of a K+ channel (Kv1.3) cRNA in fertilized eggs leads to functional expression in cultured myotomal muscle cells from Xenopus embryos. Febs Letters. 348: 259-62. PMID 7518400 DOI: 10.1016/0014-5793(94)00622-9  0.702
1994 Lazdunski M, Allard B, Bernardi H, Weille JD, Fosset M, Heurteaux C, Honoré E. ATP-sensitive K+ channels. Kidney & Blood Pressure Research. 17: 118-120. DOI: 10.1159/000173797  0.513
1994 Lazdunski M. ATP-Sensitive Potassium Channels Journal of Cardiovascular Pharmacology. 24: S1-S5. DOI: 10.1097/00005344-199424004-00001  0.483
1994 Champigny G, Voilley N, Lingueglia E, Friend V, Barbry P, Lazdunski M. Regulation of expression of the lung amiloride-sensitive Na+ channel by steroid hormones. The Embo Journal. 13: 2177-2181. DOI: 10.1002/J.1460-2075.1994.Tb06494.X  0.496
1993 Bernardi H, De Weille JR, Epelbaum J, Mourre C, Amoroso S, Slama A, Fosset M, Lazdunski M. ATP-modulated K+ channels sensitive to antidiabetic sulfonylureas are present in adenohypophysis and are involved in growth hormone release. Proceedings of the National Academy of Sciences of the United States of America. 90: 1340-4. PMID 8433992 DOI: 10.1073/PNAS.90.4.1340  0.446
1993 Chevillard C, Attali B, Lesage F, Fontes M, Barhanin J, Lazdunski M, Mattei MG. Localization of a potassium channel gene (KCNE1) to 21q22.1-q22.2 by in situ hybridization and somatic cell hybridization. Genomics. 15: 243-5. PMID 8432548 DOI: 10.1006/Geno.1993.1051  0.695
1993 Heurteaux C, Bertaina V, Widmann C, Lazdunski M. K+ channel openers prevent global ischemia-induced expression of c-fos, c-jun, heat shock protein, and amyloid beta-protein precursor genes and neuronal death in rat hippocampus. Proceedings of the National Academy of Sciences of the United States of America. 90: 9431-5. PMID 8415718 DOI: 10.1073/Pnas.90.20.9431  0.499
1993 Attali B, Guillemare E, Lesage F, Honoré E, Romey G, Lazdunski M, Barhanin J. The protein IsK is a dual activator of K+ and Cl- channels. Nature. 365: 850-2. PMID 8413671 DOI: 10.1038/365850A0  0.734
1993 Lingueglia E, Voilley N, Waldmann R, Lazdunski M, Barbry P. Expression cloning of an epithelial amiloride-sensitive Na+ channel: A new channel type with homologies to Caenorhabditis elegans degenerins Febs Letters. 318: 95-99. PMID 8382172 DOI: 10.1016/0014-5793(93)81336-X  0.526
1993 Lingueglia E, Renard S, Voilley N, Waldmann R, Chassande O, Lazdunski M, Barbry P. Molecular cloning and functional expression of different molecular forms of rat amiloride-binding proteins. European Journal of Biochemistry. 216: 679-87. PMID 8375402 DOI: 10.1111/J.1432-1033.1993.Tb18188.X  0.448
1993 Allard B, Lazdunski M. Pharmacological properties of ATP-sensitive K+ channels in mammalian skeletal muscle cells. European Journal of Pharmacology. 236: 419-26. PMID 8359200 DOI: 10.1016/0014-2999(93)90480-6  0.544
1993 Honoré E, Lazdunski M. Single-channel properties and regulation of pinacidil/glibenclamide-sensitive K+ channels in follicular cells from Xenopus oocyte. Pflugers Archiv : European Journal of Physiology. 424: 113-21. PMID 7692382 DOI: 10.1007/Bf00374601  0.559
1993 Allard B, Lazdunski M. Nucleotide diphosphates activate the ATP-sensitive potassium channel in mouse skeletal muscle. Pflugers Archiv : European Journal of Physiology. 422: 185-92. PMID 1488275 DOI: 10.1007/Bf00370419  0.513
1993 Guillemare E, Honoré E, Pradier L, Lesage F, Schweitz H, Attali B, Barhanin J, Lazdunski M. Effects of the level of mRNA expression on biophysical properties, sensitivity to neurotoxins, and regulation of the brain delayed-rectifier K+ channels Kv1.2. Biochemistry. 31: 12463-8. PMID 1281425 DOI: 10.1021/Bi00164A024  0.711
1992 Auguste P, Hugues M, Mourre C, Moinier D, Tartar A, Lazdunski M. Scyllatoxin, a blocker of Ca(2+)-activated K+ channels: structure-function relationships and brain localization of the binding sites. Biochemistry. 31: 648-54. PMID 1731919 DOI: 10.1021/Bi00118A003  0.408
1992 Bois P, Romey G, Lazdunski M. Indolizinsulphones. A class of blockers with dual but discriminative effects on L-type Ca2+ channel activity and excitation-contraction coupling in skeletal muscle. Pflugers Archiv : European Journal of Physiology. 419: 651-6. PMID 1724076 DOI: 10.1007/Bf00370310  0.446
1992 Van Renterghem C, Lazdunski M. A new non-voltage-dependent, epithelial-like Na+ channel in vascular smooth muscle cells. Pflugers Archiv : European Journal of Physiology. 419: 401-8. PMID 1660598 DOI: 10.1007/BF00371123  0.383
1992 Szewczyk A, De Weille JR, Lazdunski M. TMB-8 (8-(N,N-diethylamino) octyl-3,4,5-trimethoxybenzoate) inhibits the ATP-sensitive K+ channel. European Journal of Pharmacology. 226: 175-7. PMID 1639113 DOI: 10.1016/0922-4106(92)90180-4  0.519
1992 Bernardi H, Fosset M, Lazdunski M. ATP/ADP binding sites are present in the sulfonylurea binding protein associated with brain ATP-sensitive K+ channels. Biochemistry. 31: 6328-32. PMID 1627571 DOI: 10.1021/Bi00142A023  0.4
1992 Attali B, Honoré E, Lesage F, Lazdunski M, Barhanin J. Regulation of a major cloned voltage-gated K+ channel from human T lymphocytes. Febs Letters. 303: 229-32. PMID 1607023 DOI: 10.1016/0014-5793(92)80526-M  0.661
1992 Wibrand F, Honoré E, Lazdunski M. Opening of glibenclamide-sensitive K+ channels in follicular cells promotes Xenopus oocyte maturation. Proceedings of the National Academy of Sciences of the United States of America. 89: 5133-7. PMID 1594622 DOI: 10.1073/Pnas.89.11.5133  0.522
1992 Müller M, Szewczyk A, De Weille JR, Lazdunski M. ATP-sensitive K+ channels in insulinoma cells are activated by nonesterified fatty acids. Biochemistry. 31: 4656-61. PMID 1581315 DOI: 10.1021/BI00134A017  0.313
1992 Lesage F, Attali B, Lazdunski M, Barhanin J. ISK, a slowly activating voltage-sensitive K+ channel. Characterization of multiple cDNAs and gene organization in the mouse. Febs Letters. 301: 168-72. PMID 1568475 DOI: 10.1016/0014-5793(92)81240-M  0.62
1992 Rehm H, Lazdunski M. Purification, affinity labeling, and reconstitution of voltage-sensitive potassium channels. Methods in Enzymology. 207: 556-64. PMID 1528125 DOI: 10.1016/0076-6879(92)07039-Q  0.549
1992 Szewczyk A, De Weille JR, Lazdunski M. 8-Methoxypsoralen blocks ATP-sensitive potassium channels and stimulates insulin release. European Journal of Pharmacology. 216: 323-6. PMID 1397018 DOI: 10.1016/0014-2999(92)90379-I  0.426
1992 Lesage F, Attali B, Lazdunski M, Barhanin J. Developmental expression of voltage-sensitive K+ channels in mouse skeletal muscle and C2C12 cells. Febs Letters. 310: 162-6. PMID 1383027 DOI: 10.1016/0014-5793(92)81320-L  0.689
1992 Van Renterghem C, Lazdunski M. A small-conductance charybdotoxin-sensitive, apamin-resistant Ca(2+)-activated K+ channel in aortic smooth muscle cells (A7r5 line and primary culture). Pflugers Archiv : European Journal of Physiology. 420: 417-23. PMID 1377376 DOI: 10.1007/Bf00374614  0.519
1992 Honore E, Attali B, Lesage F, Barhanin J, Lazdunski M. Receptor-mediated regulation of IsK, a very slowly activating, voltage-dependent K+ channel in Xenopus oocytes. Biochemical and Biophysical Research Communications. 184: 1135-41. PMID 1375454 DOI: 10.1016/S0006-291X(05)80001-4  0.666
1992 Fosset M, Epelbaum J, Lazdunski M. Antidiabetic sulfonylureas antagonize somatostatin inhibition of prolactin secretion in vitro. European Journal of Pharmacology. 220: 273-4. PMID 1358652 DOI: 10.1016/0014-2999(92)90760-2  0.461
1992 Amalric M, Heurteaux C, Nieoullon A, Lazdunski M. Behavioral effects of modulators of ATP-sensitive K+ channels in the rat dorsal pallidum. European Journal of Pharmacology. 217: 71-7. PMID 1356801 DOI: 10.1016/0014-2999(92)90513-4  0.478
1992 De Weille JR, Fosset M, Epelbaum J, Lazdunski M. Effectors of ATP-sensitive K+ channels inhibit the regulatory effects of somatostatin and GH-releasing factor on growth hormone secretion. Biochemical and Biophysical Research Communications. 187: 1007-14. PMID 1356334 DOI: 10.1016/0006-291X(92)91297-4  0.49
1992 Auguste P, Hugues M, Borsotto M, Thibault J, Romey G, Coppola T, Lazdunski M. Characterization and partial purification from pheochromocytoma cells of an endogenous equivalent of scyllatoxin, a scorpion toxin which blocks small conductance Ca(2+)-activated K+ channels. Brain Research. 599: 230-6. PMID 1337858 DOI: 10.1016/0006-8993(92)90396-Q  0.465
1992 Lazdunski M. Potassium channels: Structure-function relationships, diversity, and pharmacology Cardiovascular Drugs and Therapy. 6: 313-319. DOI: 10.1007/BF00051016  0.337
1992 Honoré E, Attali B, Romey G, Lesage F, Barhanin J, Lazdunski M. Different types of K+ channel current are generated by different levels of a single mRNA. The Embo Journal. 11: 2465-2471. DOI: 10.1002/J.1460-2075.1992.Tb05311.X  0.723
1991 Mourre C, Smith ML, Siesjö BK, Lazdunski M. Brain ischemia alters the density of binding sites for glibenclamide, a specific blocker of ATP-sensitive K+ channels. Brain Research. 526: 147-52. PMID 2127731 DOI: 10.1016/0006-8993(90)90262-A  0.435
1991 de Weille JR, Lazdunski M. Regulation of the ATP-sensitive potassium channel. Ion Channels. 2: 205-22. PMID 2102815 DOI: 10.1007/978-1-4615-7305-0_6  0.388
1991 Stutzmann JM, Böhme GA, Gandolfo G, Gottesmann C, Lafforgue J, Blanchard JC, Laduron PM, Lazdunski M. Riluzole prevents hyperexcitability produced by the mast cell degranulating peptide and dendrotoxin I in the rat. European Journal of Pharmacology. 193: 223-9. PMID 2050198 DOI: 10.1016/0014-2999(91)90040-W  0.343
1991 Mourre C, Widmann C, Lazdunski M. Saxitoxin-sensitive Na+ channels: presynaptic localization in cerebellum and hippocampus of neurological mutant mice. Brain Research. 533: 196-202. PMID 1963107 DOI: 10.1016/0006-8993(90)91340-M  0.383
1991 Heurteaux C, Lazdunski M. MCD peptide and dendrotoxin I activate c-fos and c-jun expression by acting on two different types of K+ channels. A discrimination using the K+ channel opener lemakalim. Brain Research. 554: 22-9. PMID 1933303 DOI: 10.1016/0006-8993(91)90167-T  0.461
1991 Messier C, Mourre C, Bontempi B, Sif J, Lazdunski M, Destrade C. Effect of apamin, a toxin that inhibits Ca(2+)-dependent K+ channels, on learning and memory processes. Brain Research. 551: 322-6. PMID 1913161 DOI: 10.1016/0006-8993(91)90950-Z  0.373
1991 Honoré E, Lazdunski M. Two different types of channels are targets for potassium channel openers in Xenopus oocytes. Febs Letters. 287: 75-9. PMID 1908792 DOI: 10.1016/0014-5793(91)80019-Y  0.507
1991 Mourre C, Widmann C, Lazdunski M. Specific hippocampal lesions indicate the presence of sulfonylurea binding sites associated to ATP-sensitive K+ channels both post-synaptically and on mossy fibers. Brain Research. 540: 340-4. PMID 1905175 DOI: 10.1016/0006-8993(91)90533-2  0.406
1991 Häusser MA, de Weille JR, Lazdunski M. Activation by cromakalim of pre- and post-synaptic ATP-sensitive K+ channels in substantia nigra. Biochemical and Biophysical Research Communications. 174: 909-14. PMID 1899575 DOI: 10.1016/0006-291X(91)91504-6  0.504
1991 de Weille JR, Schweitz H, Maes P, Tartar A, Lazdunski M. Calciseptine, a peptide isolated from black mamba venom, is a specific blocker of the L-type calcium channel. Proceedings of the National Academy of Sciences of the United States of America. 88: 2437-40. PMID 1848702 DOI: 10.1073/Pnas.88.6.2437  0.435
1991 Dalemans W, Barbry P, Champigny G, Jallat S, Dott K, Dreyer D, Crystal RG, Pavirani A, Lecocq JP, Lazdunski M. Altered chloride ion channel kinetics associated with the delta F508 cystic fibrosis mutation. Nature. 354: 526-8. PMID 1722027 DOI: 10.1038/354526A0  0.349
1991 Champigny G, Verrier B, Lazdunski M. A voltage, calcium, and ATP sensitive non selective cation channel in human colonic tumor cells. Biochemical and Biophysical Research Communications. 176: 1196-203. PMID 1710111 DOI: 10.1016/0006-291X(91)90412-Z  0.536
1991 Schaeffer P, Lazdunski M. K+ efflux pathways and neurotransmitter release associated to hippocampal ischemia: effects of glucose and of K+ channel blockers Brain Research. 539: 155-158. PMID 1707738 DOI: 10.1016/0006-8993(91)90699-V  0.448
1991 Müller M, De Weille JR, Lazdunski M. Chlorpromazine and related phenothiazines inhibit the ATP-sensitive K+ channel. European Journal of Pharmacology. 198: 101-4. PMID 1680711 DOI: 10.1016/0014-2999(91)90569-C  0.528
1991 Moll C, Mourre C, Lazdunski M, Ulrich J. Increase of sodium channels in demyelinated lesions of multiple sclerosis. Brain Research. 556: 311-6. PMID 1657307 DOI: 10.1016/0006-8993(91)90321-L  0.395
1991 Honoré E, Lazdunski M. Hormone-regulated K+ channels in follicle-enclosed oocytes are activated by vasorelaxing K+ channel openers and blocked by antidiabetic sulfonylureas. Proceedings of the National Academy of Sciences of the United States of America. 88: 5438-42. PMID 1647032 DOI: 10.1073/Pnas.88.12.5438  0.547
1991 Honoré E, Attali B, Romey G, Heurteaux C, Ricard P, Lesage F, Lazdunski M, Barhanin J. Cloning, expression, pharmacology and regulation of a delayed rectifier K+ channel in mouse heart. The Embo Journal. 10: 2805-2811. DOI: 10.1002/J.1460-2075.1991.Tb07829.X  0.694
1990 Schweitz H, Bidard JN, Maes P, Lazdunski M. Charybdotoxin is a new member of the K+ channel toxin family that includes dendrotoxin I and mast cell degranulating peptide. Biochemistry. 28: 9708-14. PMID 2482078 DOI: 10.1021/Bi00451A025  0.544
1990 Séquier JM, Lazdunski M. Mast cell degranulating peptide induces the expression of the c-fos proto-oncogene in hippocampus. European Journal of Pharmacology. 180: 179-81. PMID 2365001 DOI: 10.1016/0014-2999(90)90607-8  0.334
1990 Schmid-Antomarchi H, Amoroso S, Fosset M, Lazdunski M. K+ channel openers activate brain sulfonylurea-sensitive K+ channels and block neurosecretion. Proceedings of the National Academy of Sciences of the United States of America. 87: 3489-92. PMID 2333295 DOI: 10.1073/Pnas.87.9.3489  0.519
1990 Séquier JM, Brennand J, Barhanin J, Lazdunski M. Regional expression of a MCD-peptide and dendrotoxin I-sensitive voltage-dependent potassium channel in rat brain. Febs Letters. 263: 163-5. PMID 2332046 DOI: 10.1016/0014-5793(90)80729-3  0.472
1990 Amoroso S, Schmid-Antomarchi H, Fosset M, Lazdunski M. Glucose, sulfonylureas, and neurotransmitter release: role of ATP-sensitive K+ channels. Science (New York, N.Y.). 247: 852-4. PMID 2305257 DOI: 10.1126/Science.2305257  0.489
1990 Barbry P, Simon-Bouy B, Mattéi MG, Le Guern E, Jaume-Roig B, Chassande O, Ullrich A, Lazdunski M. Localization of the gene for amiloride binding protein on chromosome 7 and RFLP analysis in cystic fibrosis families. Human Genetics. 85: 587-9. PMID 2227949 DOI: 10.1007/Bf00193579  0.356
1990 de Weille JR, Lazdunski M. ATP-sensitive K+ channels reveal the effects of intracellular chloride variations on cytoplasmic ATP concentrations and mitochondrial function. Biochemical and Biophysical Research Communications. 168: 1137-42. PMID 2161214 DOI: 10.1016/0006-291X(90)91147-K  0.504
1990 Barbry P, Chassande O, Marsault R, Lazdunski M, Frelin C. [3H]phenamil binding protein of the renal epithelium Na+ channel. Purification, affinity labeling, and functional reconstitution. Biochemistry. 29: 1039-45. PMID 2160271 DOI: 10.1021/Bi00456A028  0.395
1990 Garcia L, Pinçon-Raymond M, Romey G, Changeux JP, Lazdunski M, Rieger F. Induction of normal ultrastructure by CGRP treatment in dysgenic myotubes. Febs Letters. 263: 147-52. PMID 2158902 DOI: 10.1016/0014-5793(90)80725-X  0.324
1990 Mourre C, Widmann C, Lazdunski M. Sulfonylurea binding sites associated with ATP-regulated K+ channels in the central nervous system: autoradiographic analysis of their distribution and ontogenesis, and of their localization in mutant mice cerebellum. Brain Research. 519: 29-43. PMID 2118822 DOI: 10.1016/0006-8993(90)90057-I  0.403
1990 Schweitz H, Bidard JN, Lazdunski M. Purification and pharmacological characterization of peptide toxins from the black mamba (Dendroaspis polylepis) venom. Toxicon : Official Journal of the International Society On Toxinology. 28: 847-56. PMID 1977212 DOI: 10.1016/S0041-0101(09)80007-X  0.306
1990 Champigny G, Verrier B, Lazdunski M. Ca2+ channel blockers inhibit secretory C1-channels in intestinal epithelial cells. Biochemical and Biophysical Research Communications. 171: 1022-8. PMID 1699519 DOI: 10.1016/0006-291X(90)90786-M  0.533
1990 Champigny G, Verrier B, Gérard C, Mauchamp J, Lazdunski M. Small conductance chloride channels in the apical membrane of thyroid cells. Febs Letters. 259: 263-8. PMID 1688416 DOI: 10.1016/0014-5793(90)80024-D  0.509
1990 Amoroso S, Schmid Antomarchi H, Fosset M, Lazdunski M. Sulfonylureas-sensitive K+-ATP channels modulate [3H] gaba release in substantia nigra Pharmacological Research. 22: 14. DOI: 10.1016/S1043-6618(09)80071-6  0.312
1990 Amoroso S, Schmid-Antomarchi H, Fosset M, Lazdunski M. Sulfonylureas-sensitive KATP channels modulate [3M]GABA release in substantia nigra European Journal of Pharmacology. 183: 459. DOI: 10.1016/0014-2999(90)93348-T  0.359
1989 Mourre C, Nehlig A, Lazdunski M. Cerebral glucose utilization after administration of apamin, a toxin active on Ca2+-dependent K+ channels. Brain Research. 451: 274-84. PMID 3251587 DOI: 10.1016/0006-8993(88)90772-X  0.346
1989 Bernardi H, Fosset M, Lazdunski M. Characterization, purification, and affinity labeling of the brain [3H]glibenclamide-binding protein, a putative neuronal ATP-regulated K+ channel. Proceedings of the National Academy of Sciences of the United States of America. 85: 9816-20. PMID 3144003 DOI: 10.1073/Pnas.85.24.9816  0.434
1989 Fosset M, Schmid-Antomarchi H, de Weille JR, Lazdunski M. Somatostatin activates glibenclamide-sensitive and ATP-regulated K+ channels in insulinoma cells via a G-protein. Febs Letters. 242: 94-6. PMID 2904889 DOI: 10.1016/0014-5793(88)80992-X  0.516
1989 Frelin C, Barbry P, Vigne P, Chassande O, Cragoe EJ, Lazdunski M. Amiloride and its analogs as tools to inhibit Na+ transport via the Na+ channel, the Na+/H+ antiport and the Na+/Ca2+ exchanger. Biochimie. 70: 1285-90. PMID 2852509 DOI: 10.1016/0300-9084(88)90196-4  0.387
1989 Rehm H, Pelzer S, Cochet C, Chambaz E, Tempel BL, Trautwein W, Pelzer D, Lazdunski M. Dendrotoxin-binding brain membrane protein displays a K+ channel activity that is stimulated by both cAMP-dependent and endogenous phosphorylations. Biochemistry. 28: 6455-60. PMID 2790006 DOI: 10.1021/Bi00441A044  0.47
1989 de Weille JR, Fosset M, Mourre C, Schmid-Antomarchi H, Bernardi H, Lazdunski M. Pharmacology and regulation of ATP-sensitive K+ channels. Pflugers Archiv : European Journal of Physiology. S80-7. PMID 2674894 DOI: 10.1007/Bf00582253  0.517
1989 de Weille JR, Schmid-Antomarchi H, Fosset M, Lazdunski M. Regulation of ATP-sensitive K+ channels in insulinoma cells: activation by somatostatin and protein kinase C and the role of cAMP. Proceedings of the National Academy of Sciences of the United States of America. 86: 2971-5. PMID 2565041 DOI: 10.1073/PNAS.86.8.2971  0.424
1989 Verrier B, Champigny G, Barbry P, Gerard C, Mauchamp J, Lazdunski M. Identification and properties of a novel type of Na+-permeable amiloride-sensitive channel in thyroid cells. European Journal of Biochemistry. 183: 499-505. PMID 2550220 DOI: 10.1111/J.1432-1033.1989.Tb21077.X  0.483
1989 Bidard JN, Mourre C, Gandolfo G, Schweitz H, Widmann C, Gottesmann C, Lazdunski M. Analogies and differences in the mode of action and properties of binding sites (localization and mutual interactions) of two K+ channel toxins, MCD peptide and dendrotoxin I. Brain Research. 495: 45-57. PMID 2550111 DOI: 10.1016/0006-8993(89)91216-X  0.34
1989 Gandolfo G, Gottesmann C, Bidard JN, Lazdunski M. Subtypes of K+ channels differentiated by the effect of K+ channel openers upon K+ channel blocker-induced seizures. Brain Research. 495: 189-92. PMID 2550110 DOI: 10.1016/0006-8993(89)91236-5  0.523
1989 Barbry P, Chassande O, Duval D, Rousseau B, Frelin C, Lazdunski M. Biochemical identification of two types of phenamil binding sites associated with amiloride-sensitive Na+ channels. Biochemistry. 28: 3744-9. PMID 2546581 DOI: 10.1021/Bi00435A018  0.467
1989 Renaud JF, Fosset M, Kazazoglou T, Lazdunski M, Schmid A. Appearance and function of voltage-dependent Ca2+ channels during pre- and postnatal development of cardiac and skeletal muscles. Annals of the New York Academy of Sciences. 560: 418-25. PMID 2545149 DOI: 10.1111/J.1749-6632.1989.Tb24126.X  0.391
1989 Barhanin J, Borsotto M, Coppola T, Fosset M, Hosey MM, Mourre C, Pauron D, Quar J, Romey G, Schmid A, Vandaele S, Van Renterghem C, Lazdunski M. Biochemistry, molecular pharmacology, and functional control of Ca2+ channels Annals of the New York Academy of Sciences. 560: 15-26. PMID 2545130 DOI: 10.1111/J.1749-6632.1989.Tb24075.X  0.408
1989 Vigne P, Lazdunski M, Frelin C. The inotropic effect of endothelin-1 on rat atria involves hydrolysis of phosphatidylinositol. Febs Letters. 249: 143-6. PMID 2544444 DOI: 10.1016/0014-5793(89)80611-8  0.355
1989 Gandolfo G, Gottesmann C, Bidard JN, Lazdunski M. Ca2+ channel blockers prevent seizures induced by a class of K+ channel inhibitors. European Journal of Pharmacology. 160: 173-7. PMID 2540990 DOI: 10.1016/0014-2999(89)90669-9  0.444
1989 Romey G, Garcia L, Dimitriadou V, Pincon-Raymond M, Rieger F, Lazdunski M. Ontogenesis and localization of Ca2+ channels in mammalian skeletal muscle in culture and role in excitation-contraction coupling. Proceedings of the National Academy of Sciences of the United States of America. 86: 2933-7. PMID 2539603 DOI: 10.1073/Pnas.86.8.2933  0.424
1989 Gandolfo G, Romettino S, Gottesmann C, van Luijtelaar G, Coenen A, Bidard JN, Lazdunski M. K+ channel openers decrease seizures in genetically epileptic rats. European Journal of Pharmacology. 167: 181-3. PMID 2506066 DOI: 10.1016/0014-2999(89)90762-0  0.41
1989 Mourre C, Ben Ari Y, Bernardi H, Fosset M, Lazdunski M. Antidiabetic sulfonylureas: localization of binding sites in the brain and effects on the hyperpolarization induced by anoxia in hippocampal slices. Brain Research. 486: 159-64. PMID 2497930 DOI: 10.1016/0006-8993(89)91288-2  0.381
1989 Schweitz H, Stansfeld CE, Bidard JN, Fagni L, Maes P, Lazdunski M. Charybdotoxin blocks dendrotoxin-sensitive voltage-activated K+ channels. Febs Letters. 250: 519-22. PMID 2473923 DOI: 10.1016/0014-5793(89)80788-4  0.494
1989 Van Renterghem C, Vigne P, Barhanin J, Schmid-Alliana A, Frelin C, Lazdunski M. Molecular mechanism of endothelin-1 action on aortic cells. Journal of Cardiovascular Pharmacology. S186-7. PMID 2473304 DOI: 10.1097/00005344-198900135-00051  0.323
1989 de Weille JR, Fosset M, Schmid-Antomarchi H, Lazdunski M. Galanin inhibits dopamine secretion and activates a potassium channel in pheochromocytoma cells. Brain Research. 485: 199-203. PMID 2470471 DOI: 10.1016/0006-8993(89)90685-9  0.509
1989 Van Renterghem C, Vigne P, Barhanin J, Schmid-Alliana A, Frelin C, Lazdunski M. Molecular mechanism of action of the vasoconstrictor peptide endothelin. Biochemical and Biophysical Research Communications. 157: 977-85. PMID 2462875 DOI: 10.1016/S0006-291X(88)80970-7  0.438
1989 Pauron D, Barhanin J, Amichot M, Pralavorio M, Berge JB, Lazdunski M. Pyrethroid receptor in the insect sodium channel: alteration of its properties in pyrethroid-resistant flies Biochemistry. 28: 1673-1677. DOI: 10.1021/Bi00430A037  0.4
1989 Auguste P, Hugues M, Lazdunski M. Polypeptide constitution of receptors for apamin, a neurotoxin which blocks a class of Ca2+-activated K+ channels Febs Letters. 248: 150-154. DOI: 10.1016/0014-5793(89)80451-X  0.462
1988 Chassande O, Frelin C, Farahifar D, Jean T, Lazdunski M. The Na+/K+/Cl- cotransport in C6 glioma cells. Properties and role in volume regulation. European Journal of Biochemistry. 171: 425-33. PMID 3345741 DOI: 10.1111/J.1432-1033.1988.Tb13807.X  0.379
1988 Hosey MM, Lazdunski M. Calcium channels: Molecular pharmacology, structure and regulation The Journal of Membrane Biology. 104: 81-105. PMID 2903935 DOI: 10.1007/Bf01870922  0.409
1988 Romey G, Garcia L, Rieger F, Lazdunski M. Targets for calcium channel blockers in mammalian skeletal muscle and their respective functions in excitation-contraction coupling. Biochemical and Biophysical Research Communications. 156: 1324-32. PMID 2847731 DOI: 10.1016/S0006-291X(88)80777-0  0.413
1988 Lombet A, Mourre C, Lazdunski M. Interaction of insecticides of the pyrethroid family with specific binding sites on the voltage-dependent sodium channel from mammalian brain. Brain Research. 459: 44-53. PMID 2844361 DOI: 10.1016/0006-8993(88)90284-3  0.457
1988 Pauron D, Qar J, Barhanin J, Fournier D, Cuany A, Pralavorio M, Berge JB, Lazdunski M. Identification and affinity labeling of very high affinity binding sites for the phenylalkylamine series of Ca+ channel blockers in the Drosophila nervous system. Biochemistry. 26: 6311-5. PMID 2827725 DOI: 10.1021/Bi00394A003  0.401
1988 Van Renterghem C, Romey G, Lazdunski M. Vasopressin modulates the spontaneous electrical activity in aortic cells (line A7r5) by acting on three different types of ionic channels. Proceedings of the National Academy of Sciences of the United States of America. 85: 9365-9. PMID 2461570 DOI: 10.1073/PNAS.85.23.9365  0.375
1988 Mourre C, Moll C, Lombet A, Lazdunski M. Distribution of voltage-dependent Na+ channels identified by high-affinity receptors for tetrodotoxin and saxitoxin in rat and human brains: quantitative autoradiographic analysis. Brain Research. 448: 128-39. PMID 2455581 DOI: 10.1016/0006-8993(88)91109-2  0.358
1988 Rehm H, Lazdunski M. Purification and subunit structure of a putative K+-channel protein identified by its binding properties for dendrotoxin I. Proceedings of the National Academy of Sciences of the United States of America. 85: 4919-23. PMID 2455300 DOI: 10.1073/Pnas.85.13.4919  0.453
1988 Rehm H, Bidard JN, Schweitz H, Lazdunski M. The receptor site for the bee venom mast cell degranulating peptide. Affinity labeling and evidence for a common molecular target for mast cell degranulating peptide and dendrotoxin I, a snake toxin active on K+ channels. Biochemistry. 27: 1827-32. PMID 2454131 DOI: 10.1021/Bi00406A005  0.428
1988 Rehm H, Lazdunski M. Existence of different populations of the dendrotoxin I binding protein associated with neuronal K+ channels. Biochemical and Biophysical Research Communications. 153: 231-40. PMID 2454106 DOI: 10.1016/S0006-291X(88)81213-0  0.342
1988 Lazdunski M, Barhanin J, Borsotto M, Cognard C, Cooper C, Coppola T, Fosset M, Galizzi JP, Hosey MM, Mourre C, Renaud JF, Romey G, Schmid A, Vandaele S. Molecular properties of structure and regulation of the calcium channel Annals of the New York Academy of Sciences. 522: 134-149. PMID 2454048 DOI: 10.1111/J.1749-6632.1988.Tb33350.X  0.403
1988 Barhanin J, Schmid A, Lazdunski M. Properties of structure and interaction of the receptor for omega-conotoxin, a polypeptide active on Ca2+ channels. Biochemical and Biophysical Research Communications. 150: 1051-62. PMID 2449205 DOI: 10.1016/0006-291X(88)90736-X  0.423
1988 de Weille J, Schmid-Antomarchi H, Fosset M, Lazdunski M. ATP-sensitive K+ channels that are blocked by hypoglycemia-inducing sulfonylureas in insulin-secreting cells are activated by galanin, a hyperglycemia-inducing hormone. Proceedings of the National Academy of Sciences of the United States of America. 85: 1312-6. PMID 2448801 DOI: 10.1073/PNAS.85.4.1312  0.441
1988 Rieger F, Bournaud R, Shimahara T, Garcia L, Pinçon-Raymond M, Romey G, Lazdunski M. Restoration of dysgenic muscle contraction and calcium channel function by co-culture with normal spinal cord neurons. Nature. 330: 563-6. PMID 2446145 DOI: 10.1038/330563A0  0.427
1988 Qar J, Galizzi JP, Fosset M, Lazdunski M. Receptors for diphenylbutylpiperidine neuroleptics in brain, cardiac, and smooth muscle membranes. Relationship with receptors for 1,4-dihydropyridines and phenylalkylamines and with Ca2+ channel blockade. European Journal of Pharmacology. 141: 261-8. PMID 2445589 DOI: 10.1016/0014-2999(87)90271-8  0.383
1988 Graziana A, Fosset M, Ranjeva R, Hetherington AM, Lazdunski M. Calcium channel inhibitors that bind to plant cell membranes block calcium entry into protoplasts Biochemistry. 27: 764-768. DOI: 10.1021/Bi00402A041  0.352
1988 Lazdunski M. Transmembrane ionic transport systems and hypertension The American Journal of Medicine. 84: 3-9. DOI: 10.1016/S0002-9343(88)90897-2  0.326
1988 Frelin C, Barbry P, Chassande O, Lazdunski M. The structure of the epithelium Na channel of pig kidney Comparative Biochemistry and Physiology Part a: Physiology. 90: 831. DOI: 10.1016/0300-9629(88)90786-4  0.465
1987 Rieger F, Pinçon-Raymond M, Tassin AM, Garcia L, Romey G, Fosset M, Lazdunski M. Excitation-contraction uncoupling in the developing skeletal muscle of the muscular dysgenesis mouse embryo. Biochimie. 69: 411-7. PMID 3115318 DOI: 10.1016/0300-9084(87)90033-2  0.36
1987 Barhanin J, Coppola T, Schmid A, Borsotto M, Lazdunski M. The calcium channel antagonists receptor from rabbit skeletal muscle. Reconstitution after purification and subunit characterization. European Journal of Biochemistry. 164: 525-31. PMID 3032621 DOI: 10.1111/J.1432-1033.1987.Tb11158.X  0.426
1987 Hosey MM, Barhanin J, Schmid A, Vandaele S, Ptasienski J, O'Callahan C, Cooper C, Lazdunski M. Photoaffinity labelling and phosphorylation of a 165 kilodalton peptide associated with dihydropyridine and phenylalkylamine-sensitive calcium channels. Biochemical and Biophysical Research Communications. 147: 1137-45. PMID 2444223 DOI: 10.1016/S0006-291X(87)80188-2  0.406
1987 Lombet A, Fosset M, Romey G, Jacomet Y, Lazdunski M. Identification in mammalian brain of an endogenous substance with Na+ channel blocking activities similar to those of tetrodotoxin. Brain Research. 417: 327-34. PMID 2443217 DOI: 10.1016/0006-8993(87)90458-6  0.462
1987 Mourre C, Cervera P, Lazdunski M. Autoradiographic analysis in rat brain of the postnatal ontogeny of voltage-dependent Na+ channels, Ca2+-dependent K+ channels and slow Ca2+ channels identified as receptors for tetrodotoxin, apamin and (-)-desmethoxyverapamil. Brain Research. 417: 21-32. PMID 2441820 DOI: 10.1016/0006-8993(87)90175-2  0.513
1987 Lombet A, Bidard JN, Lazdunski M. Ciguatoxin and brevetoxins share a common receptor site on the neuronal voltage-dependent Na+ channel. Febs Letters. 219: 355-9. PMID 2440718 DOI: 10.1016/0014-5793(87)80252-1  0.496
1987 Schmid-Antomarchi H, de Weille J, Fosset M, Lazdunski M. The antidiabetic sulfonylurea glibenclamide is a potent blocker of the ATP-modulated K+ channel in insulin secreting cells. Biochemical and Biophysical Research Communications. 146: 21-5. PMID 2440431 DOI: 10.1016/0006-291X(87)90684-X  0.52
1987 Barbry P, Chassande O, Vigne P, Frelin C, Ellory C, Cragoe EJ, Lazdunski M. Purification and subunit structure of the [3H]phenamil receptor associated with the renal apical Na+ channel. Proceedings of the National Academy of Sciences of the United States of America. 84: 4836-40. PMID 2440032 DOI: 10.1073/Pnas.84.14.4836  0.51
1987 Bidard JN, Mourre C, Lazdunski M. Two potent central convulsant peptides, a bee venom toxin, the MCD peptide, and a snake venom toxin, dendrotoxin I, known to block K+ channels, have interacting receptor sites. Biochemical and Biophysical Research Communications. 143: 383-9. PMID 2435287 DOI: 10.1016/0006-291X(87)90677-2  0.328
1987 Lazdunski M, Frelin C, Barhanin J, Lombet A, Meiri H, Pauron D, Romey G, Schmid A, Schweitz H, Vigne P. Polypeptide toxins as tools to study voltage-sensitive Na+ channels. Annals of the New York Academy of Sciences. 479: 204-20. PMID 2433992 DOI: 10.1111/J.1749-6632.1986.Tb15571.X  0.485
1987 Romey G, Quast U, Pauron D, Frelin C, Renaud JF, Lazdunski M. Na+ channels as sites of action of the cardioactive agent DPI 201-106 with agonist and antagonist enantiomers. Proceedings of the National Academy of Sciences of the United States of America. 84: 896-900. PMID 2433694 DOI: 10.1073/Pnas.84.3.896  0.486
1987 Lazdunski M, Schmid A, Romey G, Renaud JF, Galizzi JP, Fosset M, Borsotto M, Barhanin J. Molecular Properties of the Voltage-Sensitive Calcium Channel Journal of Cardiovascular Pharmacology. 9: S10-S16. DOI: 10.1097/00005344-198700094-00003  0.41
1987 Vandaele S, Fosset M, Galizzi JP, Lazdunski M. Monoclonal antibodies that coimmunoprecipitate the 1,4-dihydropyridine and phenylalkylamine receptors and reveal the Ca2+ channel structure. Biochemistry. 26: 5-9. DOI: 10.1007/978-1-4684-5598-4_6  0.412
1986 Frelin C, Chassande O, Lazdunski M. Biochemical characterization of the Na+/K+/Cl- co-transport in chick cardiac cells. Biochemical and Biophysical Research Communications. 134: 326-31. PMID 3947328 DOI: 10.1016/0006-291X(86)90566-8  0.364
1986 Frelin C, Barbry P, Green RD, Jean T, Vigne P, Lazdunski M. The Na+/H+ antiport of eukaryotic cells: Relationship between the kinetic properties of the system and its physiological function Biochimie. 68: 1279-1285. PMID 3024744 DOI: 10.1016/S0300-9084(86)80079-7  0.322
1986 Jean T, Frelin C, Vigne P, Lazdunski M. The Na+/H+ exchange system in glial cell lines. Properties and activation by an hyperosmotic shock. European Journal of Biochemistry. 160: 211-9. PMID 3021452 DOI: 10.1111/J.1432-1033.1986.Tb09959.X  0.321
1986 Frelin C, Vigne P, Barbry P, Lazdunski M. Interaction of guanidinium and guanidinium derivatives with the Na+/H+ exchange system. European Journal of Biochemistry. 154: 241-5. PMID 3002793 DOI: 10.1111/J.1432-1033.1986.Tb09388.X  0.388
1986 Lazdunski M, Frelin C, Vigne P. The sodium/hydrogen exchange system in cardiac cells: its biochemical and pharmacological properties and its role in regulating internal concentrations of sodium and internal pH. Journal of Molecular and Cellular Cardiology. 17: 1029-42. PMID 3001319 DOI: 10.1016/S0022-2828(85)80119-X  0.341
1986 Schweitz H, Renaud JF, Randimbivololona N, Préau C, Schmid A, Romey G, Rakotovao L, Lazdunski M. Purification, subunit structure and pharmacological effects on cardiac and smooth muscle cells of a polypeptide toxin isolated from the marine snail Conus tessulatus. European Journal of Biochemistry / Febs. 161: 787-92. PMID 2431907 DOI: 10.1111/J.1432-1033.1986.Tb10508.X  0.394
1986 Schmid A, Barhanin J, Mourre C, Coppola T, Borsotto M, Lazdunski M. Antibodies reveal the cytolocalization and subunit structure of the 1,4-dihydropyridine component of the neuronal Ca2+ channel. Biochemical and Biophysical Research Communications. 139: 996-1002. PMID 2429660 DOI: 10.1016/S0006-291X(86)80276-5  0.397
1986 Dreyfus P, Rieger F, Murawsky M, Garcia L, Lombet A, Fosset M, Pauron D, Barhanin J, Lazdunski M. The voltage-dependent sodium channel is co-localized with the acetylcholine receptor at the vertebrate neuromuscular junction. Biochemical and Biophysical Research Communications. 139: 196-201. PMID 2429650 DOI: 10.1016/S0006-291X(86)80098-5  0.464
1986 Renaud JF, Schmid A, Romey G, Nano JL, Lazdunski M. Mevinolin, an inhibitor of cholesterol biosynthesis, drastically depresses Ca2+ channel activity and uncouples excitation from contraction in cardiac cells in culture. Proceedings of the National Academy of Sciences of the United States of America. 83: 8007-11. PMID 2429325 DOI: 10.1073/Pnas.83.20.8007  0.416
1986 Galizzi JP, Fosset M, Romey G, Laduron P, Lazdunski M. Neuroleptics of the diphenylbutylpiperidine series are potent calcium channel inhibitors. Proceedings of the National Academy of Sciences of the United States of America. 83: 7513-7. PMID 2429309 DOI: 10.1073/Pnas.83.19.7513  0.365
1986 Mourre C, Hugues M, Lazdunski M. Quantitative autoradiographic mapping in rat brain of the receptor of apamin, a polypeptide toxin specific for one class of Ca2+-dependent K+ channels. Brain Research. 382: 239-49. PMID 2428440 DOI: 10.1016/0006-8993(86)91333-8  0.381
1986 Amédée T, Renaud JF, Jmari K, Lombet A, Mironneau J, Lazdunski M. The presence of Na+ channels in myometrial smooth muscle cells is revealed by specific neurotoxins. Biochemical and Biophysical Research Communications. 137: 675-81. PMID 2425801 DOI: 10.1016/0006-291X(86)91131-9  0.519
1986 Qar J, Schweitz H, Schmid A, Lazdunski M. A polypeptide toxin from the coral Goniopora. Purification and action on Ca2+ channels. Febs Letters. 202: 331-6. PMID 2424789 DOI: 10.1016/0014-5793(86)80712-8  0.434
1986 Schmid A, Barhanin J, Coppola T, Borsotto M, Lazdunski M. Immunochemical analysis of subunit structures of 1,4-dihydropyridine receptors associated with voltage-dependent Ca2+ channels in skeletal, cardiac, and smooth muscles. Biochemistry. 25: 3492-5. PMID 2424495 DOI: 10.1021/Bi00360A002  0.32
1986 Romey G, Rieger F, Renaud JF, Pinçon-Raymond M, Lazdunski M. The electrophysiological expression of Ca2+ channels and of apamin sensitive Ca2+ activated K+ channels is abolished in skeletal muscle cells from mice with muscular dysgenesis. Biochemical and Biophysical Research Communications. 136: 935-40. PMID 2424440 DOI: 10.1016/0006-291X(86)90422-5  0.475
1986 Hosey MM, Borsotto M, Lazdunski M. Phosphorylation and dephosphorylation of dihydropyridine-sensitive voltage-dependent Ca2+ channel in skeletal muscle membranes by cAMP- and Ca2+-dependent processes Proceedings of the National Academy of Sciences of the United States of America. 83: 3733-3737. PMID 2424010 DOI: 10.1073/Pnas.83.11.3733  0.363
1986 Frelin C, Cognard C, Vigne P, Lazdunski M. Tetrodotoxin-sensitive and tetrodotoxin-resistant Na+ channels differ in their sensitivity to Cd2+ and Zn2+. European Journal of Pharmacology. 122: 245-50. PMID 2423344 DOI: 10.1016/0014-2999(86)90109-3  0.452
1986 Lombet A, Laduron P, Mourre C, Jacomet Y, Lazdunski M. Axonal transport of Na+,K+-ATPase identified as a ouabain binding site in rat sciatic nerve. Neuroscience Letters. 64: 177-83. PMID 2421205 DOI: 10.1016/0304-3940(86)90096-0  0.342
1986 Barbry P, Frelin C, Vigne P, Cragoe EJ, Lazdunski M. [3H]phenamil, a radiolabelled diuretic for the analysis of the amiloride-sensitive Na+ channels in kidney membranes. Biochemical and Biophysical Research Communications. 135: 25-32. PMID 2420329 DOI: 10.1016/0006-291X(86)90937-X  0.455
1986 Cognard C, Romey G, Galizzi JP, Fosset M, Lazdunski M. Dihydropyridine-sensitive Ca2+ channels in mammalian skeletal muscle cells in culture: electrophysiological properties and interactions with Ca2+ channel activator (Bay K8644) and inhibitor (PN 200-110). Proceedings of the National Academy of Sciences of the United States of America. 83: 1518-22. PMID 2419909 DOI: 10.1073/Pnas.83.5.1518  0.49
1986 Desnuelle C, Renaud JF, Delpont E, Serratrice G, Lazdunski M. [3H]nitrendipine receptors as markers of a class of putative voltage-sensitive Ca2+ channels in normal human skeletal muscle and in muscle from Duchenne muscular dystrophy patients. Muscle & Nerve. 9: 148-51. PMID 2419753 DOI: 10.1002/Mus.880090207  0.344
1986 Renaud JF, Fosset M, Schweitz H, Lazdunski M. The interaction of polypeptide neurotoxins with tetrodotoxin-resistant Na+ channels in mammalian cardiac cells. Correlation with inotropic and arrhythmic effects. European Journal of Pharmacology. 120: 161-70. PMID 2419144 DOI: 10.1016/0014-2999(86)90536-4  0.462
1986 Cognard C, Lazdunski M, Romey G. Different types of Ca2+ channels in mammalian skeletal muscle cells in culture. Proceedings of the National Academy of Sciences of the United States of America. 83: 517-21. PMID 2417248 DOI: 10.1073/Pnas.83.2.517  0.466
1986 Pinçon-Raymond M, Rieger F, Fosset M, Lazdunski M. Abnormal transverse tubule system and abnormal amount of receptors for Ca2+ channel inhibitors of the dihydropyridine family in skeletal muscle from mice with embryonic muscular dysgenesis. Developmental Biology. 112: 458-66. PMID 2416618 DOI: 10.1016/0012-1606(85)90418-X  0.367
1986 Lombet A, Laduron P, Mourre C, Jacomet Y, Lazdunski M. Axonal transport of the voltage-dependent Na+ channel protein identified by its tetrodotoxin binding site in rat sciatic nerves. Brain Research. 345: 153-8. PMID 2415212 DOI: 10.1016/0006-8993(85)90846-7  0.423
1986 Lazdunski M, Barhanin J, Borsotto M, Fosset M, Galizzi J, Renaud JF, Romey G, Schmid A. Dihydropyridine-Sensitive Ca2+ Channels Journal of Cardiovascular Pharmacology. 8: S13-S19. DOI: 10.1097/00005344-198600088-00004  0.308
1985 Renaud JF, Méaux JP, Romey G, Schmid A, Lazdunski M. Activation of the voltage-dependent Ca2+ channel in rat heart cells by dihydropyridine derivatives. Biochemical and Biophysical Research Communications. 125: 405-12. PMID 6210086 DOI: 10.1016/S0006-291X(84)80382-4  0.443
1985 Lazdunski M, Kazazoglou T, Renaud JF, Rossi B. Digitalis receptors in cardiac cells and their relation with positive inotropic and cardiotoxic effects. European Heart Journal. 281-90. PMID 6099803 DOI: 10.1093/Eurheartj/5.Suppl_F.281  0.373
1985 Mourre C, Lombet A, Lazdunski M. Autoradiographic localization of tetrodotoxin-sensitive Na+ channels in rat brain. Neuroscience Letters. 52: 31-5. PMID 6098876 DOI: 10.1016/0304-3940(84)90346-X  0.499
1985 Fosset M, Schmid-Antomarchi H, Hugues M, Romey G, Lazdunski M. The presence in pig brain of an endogenous equivalent of apamin, the bee venom peptide that specifically blocks Ca2+-dependent K+ channels. Proceedings of the National Academy of Sciences of the United States of America. 81: 7228-32. PMID 6095277 DOI: 10.1073/Pnas.81.22.7228  0.457
1985 Galizzi JP, Fosset M, Lazdunski M. Characterization of the Ca2+ coordination site regulating binding of Ca2+ channel inhibitors d-cis-diltiazem, (+/-)bepridil and (-)desmethoxyverapamil to their receptor site in skeletal muscle transverse tubule membranes. Biochemical and Biophysical Research Communications. 132: 49-55. PMID 2998366 DOI: 10.1016/0006-291X(85)90986-6  0.394
1985 Frelin C, Vigne P, Lazdunski M. The role of the Na+/H+ exchange system in the regulation of the internal pH in cultured cardiac cells. European Journal of Biochemistry. 149: 1-4. PMID 2986967 DOI: 10.1111/J.1432-1033.1985.Tb08884.X  0.326
1985 Vigne P, Frelin C, Lazdunski M. [The Na+/H+ exchanger in eukaryotic cells: biochemical and pharmacological properties and physiological role]. Biochimie. 67: 129-35. PMID 2986726 DOI: 10.1016/S0300-9084(85)80238-8  0.321
1985 Schmid-Antomarchi H, Renaud JF, Romey G, Hugues M, Schmid A, Lazdunski M. The all-or-none role of innervation in expression of apamin receptor and of apamin-sensitive Ca2+-activated K+ channel in mammalian skeletal muscle. Proceedings of the National Academy of Sciences of the United States of America. 82: 2188-91. PMID 2580309 DOI: 10.1073/Pnas.82.7.2188  0.461
1985 Barhanin J, Meiri H, Romey G, Pauron D, Lazdunski M. A monoclonal immunotoxin acting on the Na+ channel, with properties similar to those of a scorpion toxin. Proceedings of the National Academy of Sciences of the United States of America. 82: 1842-6. PMID 2580299 DOI: 10.1073/Pnas.82.6.1842  0.514
1985 Pauron D, Barhanin J, Lazdunski M. The voltage-dependent Na+ channel of insect nervous system identified by receptor sites for tetrodotoxin, and scorpion and sea anemone toxins. Biochemical and Biophysical Research Communications. 131: 1226-33. PMID 2413857 DOI: 10.1016/0006-291X(85)90222-0  0.526
1985 Schweitz H, Bidard JN, Frelin C, Pauron D, Vijverberg HP, Mahasneh DM, Lazdunski M, Vilbois F, Tsugita A. Purification, sequence, and pharmacological properties of sea anemone toxins from Radianthus paumotensis. A new class of sea anemone toxins acting on the sodium channel. Biochemistry. 24: 3554-61. PMID 2412579 DOI: 10.1021/Bi00335A025  0.464
1985 Ildefonse M, Jacquemond V, Rougier O, Renaud JF, Fosset M, Lazdunski M. Excitation contraction coupling in skeletal muscle: evidence for a role of slow Ca2+ channels using Ca2+ channel activators and inhibitors in the dihydropyridine series. Biochemical and Biophysical Research Communications. 129: 904-9. PMID 2409971 DOI: 10.1016/0006-291X(85)91977-1  0.4
1984 Galizzi JP, Fosset M, Lazdunski M. [3H] verapamil binding sites in skeletal muscle transverse tubule membranes. Biochemical and Biophysical Research Communications. 118: 239-45. PMID 6696758 DOI: 10.1016/0006-291X(84)91092-1  0.325
1984 Lazdunski M, Kazazoglou T, Renaud JF, Rossi B. Digitalis receptors affinity labelling and relation with positive inotropic and cardiotoxic effects. Basic Research in Cardiology. 110-8. PMID 6331370 DOI: 10.1007/978-3-642-72376-6_15  0.384
1984 Schmid A, Kazazoglou T, Renaud JF, Lazdunski M. Comparative changes of levels of nitrendipine Ca2+ channels, of tetrodotoxin-sensitive Na+ channels and of ouabain-sensitive (Na+ + K+)-ATPase following denervation of rat and chick skeletal muscle. Febs Letters. 172: 114-8. PMID 6329821 DOI: 10.1016/0014-5793(84)80885-6  0.511
1984 Mourre C, Schmid-Antomarchi H, Hugues M, Lazdunski M. Autoradiographic localization of apamin-sensitive Ca2+-dependent K+ channels in rat brain. European Journal of Pharmacology. 100: 135-6. PMID 6327325 DOI: 10.1016/0014-2999(84)90329-7  0.449
1984 Barhanin J, Ildefonse M, Rougier O, Sampaio SV, Giglio JR, Lazdunski M. Tityus gamma toxin, a high affinity effector of the Na+ channel in muscle, with a selectivity for channels in the surface membrane. Pflugers Archiv : European Journal of Physiology. 400: 22-7. PMID 6324066 DOI: 10.1007/Bf00670531  0.477
1984 Lazdunski M. Apamin, a neurotoxin specific for one class of Ca2+-dependent K+ channels. Cell Calcium. 4: 421-8. PMID 6323004 DOI: 10.1016/0143-4160(83)90018-0  0.381
1984 Romey G, Lazdunski M. The coexistence in rat muscle cells of two distinct classes of Ca2+-dependent K+ channels with different pharmacological properties and different physiological functions. Biochemical and Biophysical Research Communications. 118: 669-74. PMID 6322759 DOI: 10.1016/0006-291X(84)91355-X  0.457
1984 Renaud JF, Kazazoglou T, Schmid A, Romey G, Lazdunski M. Differentiation of receptor sites for [3H]nitrendipine in chick hearts and physiological relation to the slow Ca2+ channel and to excitation-contraction coupling. European Journal of Biochemistry. 139: 673-81. PMID 6321185 DOI: 10.1111/J.1432-1033.1984.Tb08056.X  0.463
1984 Bidard JN, Rossi B, Renaud JF, Lazdunski M. A search for an 'ouabain-like' substance from the electric organ of Electrophorus electricus which led to arachidonic acid and related fatty acids. Biochimica Et Biophysica Acta. 769: 245-52. PMID 6318825 DOI: 10.1016/0005-2736(84)90029-4  0.317
1984 Kazazoglou T, Schmid A, Renaud JF, Lazdunski M. Ontogenic appearance of Ca2+ channels characterized as binding sites for nitrendipine during development of nervous, skeletal and cardiac muscle systems in the rat. Febs Letters. 164: 75-9. PMID 6317445 DOI: 10.1016/0014-5793(83)80022-2  0.346
1984 Frelin C, Vijverberg HP, Romey G, Vigne P, Lazdunski M. Different functional states of tetrodotoxin sensitive and tetrodotoxin resistant Na+ channels occur during the in vitro development of rat skeletal muscle. Pflã¼Gers Archiv : European Journal of Physiology. 402: 121-8. PMID 6098891 DOI: 10.1007/Bf00583323  0.524
1984 Galizzi JP, Fosset M, Lazdunski M. Properties of receptors for the Ca2+-channel blocker verapamil in transverse-tubule membranes of skeletal muscle. Stereospecificity, effect of Ca2+ and other inorganic cations, evidence for two categories of sites and effect of nucleoside triphosphates. European Journal of Biochemistry. 144: 211-5. PMID 6092067 DOI: 10.1111/J.1432-1033.1984.Tb08451.X  0.417
1984 Borsotto M, Barhanin J, Norman RI, Lazdunski M. Purification of the dihydropyridine receptor of the voltage-dependent Ca2+ channel from skeletal muscle transverse tubules using (+) [3H]PN 200-110. Biochemical and Biophysical Research Communications. 122: 1357-66. PMID 6089781 DOI: 10.1016/0006-291X(84)91241-5  0.402
1984 Vijverberg HP, Pauron D, Lazdunski M. The effect of Tityus serrulatus scorpion toxin gamma on Na channels in neuroblastoma cells. Pflã¼Gers Archiv : European Journal of Physiology. 401: 297-303. PMID 6089101 DOI: 10.1007/Bf00582600  0.467
1984 Borsotto M, Norman RI, Fosset M, Lazdunski M. Solubilization of the nitrendipine receptor from skeletal muscle transverse tubule membranes. Interactions with specific inhibitors of the voltage-dependent Ca2+ channel. European Journal of Biochemistry. 142: 449-55. PMID 6088224 DOI: 10.1111/J.1432-1033.1984.Tb08307.X  0.381
1984 Schmid-Antomarchi H, Hugues M, Norman R, Ellory C, Borsotto M, Lazdunski M. Molecular properties of the apamin-binding component of the Ca2+-dependent K+ channel. Radiation-inactivation, affinity labelling and solubilization. European Journal of Biochemistry. 142: 1-6. PMID 6086337 DOI: 10.1111/J.1432-1033.1984.Tb08242.X  0.437
1984 Lombet A, Lazdunski M. Characterization, solubilization, affinity labeling and purification of the cardiac Na+ channel using Tityus toxin gamma. European Journal of Biochemistry. 141: 651-60. PMID 6086336 DOI: 10.1111/J.1432-1033.1984.Tb08241.X  0.425
1984 RENAUD J, LOMBET A, ROMEY G, KAZAZOGLOU T, JAIMOVICH E, CHICHEPORTICHE R, LAZDUNSKI M. The Na+ channel in mammalian heart. Two kinds of tetrodotoxin receptors Journal of Molecular and Cellular Cardiology. 16: 8-8. DOI: 10.1016/S0022-2828(84)80381-8  0.458
1984 RENAUD J, MEAUX J, ROMEY G, LAZDUNSKI M. Receptor sites for dihydropyridines associated with calcium channel blockade/calcium channel activation Journal of Molecular and Cellular Cardiology. 16: 13-13. DOI: 10.1016/S0022-2828(84)80314-4  0.426
1984 Vigne P, Frelin C, Lazdunski M. The Na+-dependent regulation of the internal pH in chick skeletal muscle cells. The role of the Na+/H+ exchange system and its dependence on internal pH. The Embo Journal. 3: 1865-1870. DOI: 10.1002/J.1460-2075.1984.Tb02060.X  0.329
1984 Hanke W, Boheim G, Barhanin J, Pauron D, Lazdunski M. Reconstitution of highly purified saxitoxin-sensitive Na+-channels into planar lipid bilayers. The Embo Journal. 3: 509-515. DOI: 10.1002/J.1460-2075.1984.Tb01839.X  0.54
1983 Barhanin J, Pauron D, Lombet A, Norman RI, Vijverberg HP, Giglio JR, Lazdunski M. Electrophysiological characterization, solubilization and purification of the Tityus gamma toxin receptor associated with the gating component of the Na+ channel from rat brain. The Embo Journal. 2: 915-20. PMID 6315420 DOI: 10.1002/J.1460-2075.1983.Tb01521.X  0.418
1983 Vigne P, Frelin C, Cragoe EJ, Lazdunski M. Ethylisopropyl-amiloride: a new and highly potent derivative of amiloride for the inhibition of the Na+/H+ exchange system in various cell types. Biochemical and Biophysical Research Communications. 116: 86-90. PMID 6315011 DOI: 10.1016/0006-291X(83)90384-4  0.325
1983 Goeldner MP, Hirth CG, Rossi B, Ponzio G, Lazdunski M. Specific photoaffinity labeling of the digitalis binding site of the sodium and potassium ion activated adenosinetriphosphatase induced by energy transfer. Biochemistry. 22: 4685-90. PMID 6313046 DOI: 10.1021/Bi00289A012  0.342
1983 Lombet A, Norman RI, Lazdunski M. Affinity labelling of the tetrodotoxin-binding component of the Na+ channel. Biochemical and Biophysical Research Communications. 114: 126-30. PMID 6309160 DOI: 10.1016/0006-291X(83)91603-0  0.364
1983 Norman RI, Schmid A, Lombet A, Barhanin J, Lazdunski M. Purification of binding protein for Tityus gamma toxin identified with the gating component of the voltage-sensitive Na+ channel. Proceedings of the National Academy of Sciences of the United States of America. 80: 4164-8. PMID 6306665 DOI: 10.1073/Pnas.80.13.4164  0.446
1983 Wheeler KP, Watt DD, Lazdunski M. Classification of Na channel receptors specific for various scorpion toxins. Pflugers Archiv : European Journal of Physiology. 397: 164-5. PMID 6306553 DOI: 10.1007/Bf00582058  0.436
1983 Jaimovich E, Chicheportiche R, Lombet A, Lazdunski M, Ildefonse M, Rougier O. Differences in the properties of Na+ channels in muscle surface and T-tubular membranes revealed by tetrodotoxin derivatives. Pflugers Archiv : European Journal of Physiology. 397: 1-5. PMID 6306551 DOI: 10.1007/Bf00585159  0.474
1983 Norman RI, Borsotto M, Fosset M, Lazdunski M, Ellory JC. Determination of the molecular size of the nitrendipine-sensitive Ca2+ channel by radiation inactivation. Biochemical and Biophysical Research Communications. 111: 878-83. PMID 6301488 DOI: 10.1016/0006-291X(83)91381-5  0.335
1983 Lombet A, Kazazoglou T, Delpont E, Renaud JF, Lazdunski M. Ontogenic appearance of Na+ channels characterized as high affinity binding sites for tetrodotoxin during development of the rat nervous and skeletal muscle systems. Biochemical and Biophysical Research Communications. 110: 894-901. PMID 6301467 DOI: 10.1016/0006-291X(83)91046-X  0.455
1983 Fosset M, Jaimovich E, Delpont E, Lazdunski M. [3H]nitrendipine labelling of the Ca2+ channel in skeletal muscle. European Journal of Pharmacology. 86: 141-2. PMID 6297924 DOI: 10.1016/0014-2999(82)90414-9  0.372
1983 Wheeler KP, Barhanin J, Lazdunski M. Specific binding of toxin II from Centruroides suffusus suffusus to the sodium channel in electroplaque membranes. Biochemistry. 21: 5628-34. PMID 6293551 DOI: 10.1021/Bi00265A037  0.411
1983 Rossi B, Ponzio G, Lazdunski M, Goeldner M, Hirth C. New Ouabain Derivatives to Covalently Label the Digitalis Binding Site Current Topics in Membranes and Transport. 19: 271-276. DOI: 10.1016/S0070-2161(08)60579-1  0.334
1982 Hugues M, Duval D, Schmid H, Kitabgi P, Lazdunski M, Vincent JP. Specific binding and pharmacological interactions of apamin, the neurotoxin from bee venom, with guinea pig colon. Life Sciences. 31: 437-43. PMID 7132561 DOI: 10.1016/0024-3205(82)90328-9  0.308
1982 Hugues M, Schmid H, Lazdunski M. Identification of a protein component of the Ca2+-dependent K+ channel by affinity labelling with apamin. Biochemical and Biophysical Research Communications. 107: 1577-82. PMID 6291536 DOI: 10.1016/S0006-291X(82)80180-0  0.506
1982 Forest C, Ponzio G, Rossi B, Lazdunski M, Ailhaud G. (Na+,K+)ATPase levels in preadipocyte cell lines established from genetically-obese and non-obese mice. Biochemical and Biophysical Research Communications. 107: 422-8. PMID 6289830 DOI: 10.1016/0006-291X(82)91508-X  0.335
1982 Frelin C, Lombet A, Vigne P, Romey G, Lazdunski M. Properties of Na+ channels in fibroblasts. Biochemical and Biophysical Research Communications. 107: 202-8. PMID 6289819 DOI: 10.1016/0006-291X(82)91689-8  0.511
1982 Tourneur Y, Romey G, Lazdunski M. Phencyclidine blockade of sodium and potassium channels in neuroblastoma cells. Brain Research. 245: 154-8. PMID 6288193 DOI: 10.1016/0006-8993(82)90351-1  0.509
1982 Jaimovich E, Ildefonse M, Barhanin J, Rougier O, Lazdunski M. Centruroides toxin, a selective blocker of surface Na+ channels in skeletal muscle: voltage-clamp analysis and biochemical characterization of the receptor. Proceedings of the National Academy of Sciences of the United States of America. 79: 3896-900. PMID 6285366 DOI: 10.1073/Pnas.79.12.3896  0.444
1982 Lombet A, Frelin C, Renaud JF, Lazdunski M. Na+ channels with binding sites of high and low affinity for tetrodotoxin in different excitable and non-excitable cells. European Journal of Biochemistry. 124: 199-203. PMID 6282588 DOI: 10.1111/J.1432-1033.1982.Tb05925.X  0.507
1982 Jacques Y, Romey G, Fosset M, Lazdunski M. Properties of the interaction of the sodium channel with permeant monovalent cations. European Journal of Biochemistry. 106: 71-83. PMID 6281000 DOI: 10.1111/J.1432-1033.1980.Tb05998.X  0.499
1982 Romey G, Lazdunski M. Lipid-soluble toxins thought to be specific for Na+ channels block Ca2+ channels in neuronal cells. Nature. 297: 79-8. PMID 6280075 DOI: 10.1038/297079A0  0.514
1982 Desnuelle C, Lombet A, Serratrice G, Lazdunski M. Sodium Channel and Sodium Pump in Normal and Pathological Muscles from Patients with Myotonic Muscular Dystrophy and Lower Motor Neuron Impairment Journal of Clinical Investigation. 69: 358-367. PMID 6276440 DOI: 10.1172/Jci110459  0.397
1982 Frelin C, Vigne P, Lazdunski M. The specificity of the sodium channel for monovalent cations. European Journal of Biochemistry. 119: 437-42. PMID 6273156 DOI: 10.1111/J.1432-1033.1981.Tb05627.X  0.543
1982 Vignon J, Vincent JP, Bidard JN, Kamenka JM, Geneste P, Monier S, Lazdunski M. Biochemical properties of the brain phencyclidine receptor. European Journal of Pharmacology. 81: 531-42. PMID 6214413 DOI: 10.1016/0014-2999(82)90342-9  0.346
1982 Frelin C, Vigne P, Lazdunski M. Biochemical evidence for pharmacological similarities between alpha-adrenoreceptors and voltage-dependent Na+ and Ca++ channels. Biochemical and Biophysical Research Communications. 106: 967-73. PMID 6126191 DOI: 10.1016/0006-291X(82)91805-8  0.488
1982 Renaud JF, Romey G, Lombet A, Lazdunski M. Developmental properties of the fast Na+ channel in embryonic cardiac cells using neurotoxins. Toxicon : Official Journal of the International Society On Toxinology. 20: 17-25. PMID 6123160 DOI: 10.1016/0041-0101(82)90139-8  0.37
1982 Hugues M, Romey G, Duval D, Vincent JP, Lazdunski M. Apamin as a selective blocker of the calcium-dependent potassium channel in neuroblastoma cells: voltage-clamp and biochemical characterization of the toxin receptor. Proceedings of the National Academy of Sciences of the United States of America. 79: 1308-12. PMID 6122211 DOI: 10.1073/Pnas.79.4.1308  0.491
1982 Renaud JF, Romey G, Lombet A, Lazdunski M. Differentiation of the fast Na+ channel in embryonic heart cells: interaction of the channel with neurotoxins. Proceedings of the National Academy of Sciences of the United States of America. 78: 5348-52. PMID 6117856 DOI: 10.1073/Pnas.78.9.5348  0.516
1982 Schweitz H, Vincent JP, Barhanin J, Frelin C, Linden G, Hugues M, Lazdunski M. Purification and pharmacological properties of eight sea anemone toxins from Anemonia sulcata, Anthopleura xanthogrammica, Stoichactis giganteus, and Actinodendron plumosum. Biochemistry. 20: 5245-52. PMID 6117312 DOI: 10.1021/Bi00521A023  0.5
1982 Hugues M, Schmid H, Romey G, Duval D, Frelin C, Lazdunski M. The Ca2+-dependent slow K+ conductance in cultured rat muscle cells: characterization with apamin. The Embo Journal. 1: 1039-1042. DOI: 10.1002/J.1460-2075.1982.Tb01293.X  0.36
1982 Rossi B, Ponzio G, Lazdunski M. Identification of the segment of the catalytic subunit of (Na+,K+)ATPase containing the digitalis binding site. The Embo Journal. 1: 859-861. DOI: 10.1002/J.1460-2075.1982.Tb01260.X  0.38
1981 Balerna M, Lombet A, Chicheportiche R, Romey G, Lazdunski M. Synthesis and properties of new photoactivable derivatives of tetrodotoxin. Biochimica Et Biophysica Acta. 644: 219-25. PMID 6789875 DOI: 10.1016/0005-2736(81)90378-3  0.391
1981 Lazdunski M, Balerna M, Barhanin J, Chicheportiche R, Fosset M, Frelin C, Jacques Y, Lombet A, Pouysségur J, Renaud JF, Romey G, Schweitz H, Vincent JP. Molecular aspects of the structure and mechanism of the voltage-dependent sodium channel. Annals of the New York Academy of Sciences. 358: 169-82. PMID 6259988 DOI: 10.1111/J.1749-6632.1980.Tb15395.X  0.451
1981 Romey G, Chicheportiche R, Lazdunski M. Transition temperatures of the electrical activity of ion channels in the nerve membrane. Biochimica Et Biophysica Acta. 602: 610-20. PMID 6254565 DOI: 10.1016/0005-2736(80)90339-9  0.431
1981 Jacques Y, Romey G, Lazdunski M. Toxin-induced K+ efflux through the Na+ channel of neuroblastoma cells. European Journal of Biochemistry. 111: 265-73. PMID 6108216 DOI: 10.1111/J.1432-1033.1980.Tb06102.X  0.514
1980 Lazdunski M, Balerna M, Barhanin J, Chicheportiche R, Fosset M, Frelin C, Jacques Y, Lombet A, Ponzio G, Pouysségur J, Renaud JF, Romey G, Schweitz H, Vincent JP. Biochemical studies of the structure, mechanism and differentiation of the voltage-sensitive sodium channel. Neurochemistry International. 2: 61-71. PMID 20487771 DOI: 10.1016/0197-0186(80)90012-1  0.476
1980 Ponzio G, Jacques Y, Frelin C, Chicheportiche R, Lazdunski M. An in vitro system to study the action potential sodium channel. Febs Letters. 121: 265-8. PMID 6257548 DOI: 10.1016/0014-5793(80)80358-9  0.534
1980 Jacques Y, Romey G, Cavey MT, Kartalovski B, Lazdunski M. Interaction of pyrethroids with the Na+ channel in mammalian neuronal cells in culture. Biochimica Et Biophysica Acta. 600: 882-97. PMID 6250606 DOI: 10.1016/0005-2736(80)90491-5  0.518
1980 Chicheportiche R, Balerna M, Lombet A, Romey G, Lazdunski M. Synthesis of new, highly radioactive tetrodotoxin derivatives and their binding properties to the sodium channel. European Journal of Biochemistry. 104: 617-25. PMID 6244958 DOI: 10.1111/J.1432-1033.1980.Tb04466.X  0.375
1980 Pouysségur J, Jacques Y, Lazdunski M. Identification of a tetrodotoxin-sensitive Na+ channel in a variety in fibroblast lines. Nature. 286: 162-4. PMID 6105618 DOI: 10.1038/286162A0  0.453
1980 Vincent JP, Balerna M, Barhanin J, Fosset M, Lazdunski M. Binding of sea anemone toxin to receptor sites associated with gating system of sodium channel in synaptic nerve endings in vitro. Proceedings of the National Academy of Sciences of the United States of America. 77: 1646-50. PMID 6103536 DOI: 10.1073/Pnas.77.3.1646  0.368
1980 Romey G, Jacques Y, Schweitz H, Fosset M, Lazdunski M. The sodium channel in non-impulsive cells. Interaction with specific neurotoxins. Biochimica Et Biophysica Acta. 556: 344-53. PMID 43740 DOI: 10.1016/0005-2736(79)90053-1  0.481
1979 Rogers TB, Lazdunski M. Photoaffinity labelling of a small protein component of a purified (Na+-K+)ATPase. Febs Letters. 98: 373-6. PMID 217738 DOI: 10.1016/0014-5793(79)80220-3  0.354
1978 Rossi B, Gache C, Lazdunski M. Specificity and interactions at the cationic sites of the axonal (Na+, K+)-activated adenosinetriphosphatase. European Journal of Biochemistry. 85: 561-70. PMID 148358 DOI: 10.1111/J.1432-1033.1978.Tb12271.X  0.378
1977 Romey G, Abita JP, Chicheportiche R, Rochat H, Lazdunski M. Scorpion neurotoxin. Mode of action on neuromuscular junctions and synaptosomes. Biochimica Et Biophysica Acta. 448: 607-19. PMID 974149 DOI: 10.1016/0005-2736(76)90114-0  0.318
1977 Gache C, Rossi B, Lazdunski M. Mechanistic analysis of the (Na+,K+)ATPase using new pseudosubstrates. Biochemistry. 16: 2957-65. PMID 18164 DOI: 10.1021/Bi00632A024  0.357
1977 Abita JP, Chicheportiche R, Schweitz H, Lazdunski M. Effects of neurotoxins (veratridine, sea anemone toxin, tetrodotoxin) on transmitter accumulation and release by nerve terminals in vitro. Biochemistry. 16: 1838-44. PMID 15589 DOI: 10.1021/Bi00628A012  0.33
1976 Gache C, Rossi B, Lazdunski M. (Na' , K+)-Activated Adenosinetriphosphatase of Axonal Membranes, Cooperativity and Control Febs Journal. 65: 293-306. PMID 132350 DOI: 10.1111/J.1432-1033.1976.Tb10417.X  0.393
1975 Chicheportiche R, Vincent JP, Kopeyan C, Schweitz H, Lazdunski M. Structure-function relationship in the binding of snake neurotoxins to the torpedo membrane receptor. Biochemistry. 14: 2081-91. PMID 1148159 DOI: 10.1021/Bi00681A007  0.31
1975 Romey G, Chicheportiche R, Lazdunski M, Rochat H, Miranda F, Lissitzky S. Scorpion neurotoxin - a presynaptic toxin which affects both Na+ and K+ channels in axons. Biochemical and Biophysical Research Communications. 64: 115-21. PMID 1147916 DOI: 10.1016/0006-291X(75)90226-0  0.439
1975 Chappelet-Tordo D, Lazdunski C, Iwatsubo M, Lazdunski M. The non-equivalence of the active sites and the mechanism of a mutationally altered E. coli alkaline phosphatase. Biochemical and Biophysical Research Communications. 63: 529-34. PMID 235925 DOI: 10.1016/0006-291X(75)90720-2  0.604
1975 Balerna M, Fosset M, Chicheportiche R, Romey G, Lazdunski M. Constitution and properties of axonal membranes of crustacean nerves. Biochemistry. 14: 5500-11. PMID 58 DOI: 10.1021/Bi00696A019  0.352
1971 Lazdunski C, Chappelet D, Petitclerc C, Leterrier F, Douzou P, Lazdunski M. The Cu2 plus-alkaline phosphatase of Escherichia coli. European Journal of Biochemistry. 17: 239-45. PMID 5500392 DOI: 10.1111/J.1432-1033.1970.Tb01159.X  0.541
1971 Lazdunski C, Petitclerc C, Chappelet D, Leterrier F, Douzou P, Lazdunski M. Tight and loose metal binding sites in the apoalkaline phosphatase of E. coli. Reconstitution of the Ca2+--phosphatase from the apoenzyme EPR study of the Mn2+-phosphatase. Biochemical and Biophysical Research Communications. 40: 589-93. PMID 5500269 DOI: 10.1016/0006-291X(70)90943-5  0.543
1971 Lazdunski M, Petitclerc C, Chappelet D, Lazdunski C. Flip-flop mechanisms in enzymology. A model: the alkaline phosphatase of Escherichia coli. European Journal of Biochemistry. 20: 124-39. PMID 4325354 DOI: 10.1111/J.1432-1033.1971.Tb01370.X  0.543
1970 Lazdunski C, Petitclerc C, Chappelet D, Lazdunski M. On the mechanism of the Zn2+ and Co2+-alkaline phosphatase of E. coli. Number of sites and anticooperativity. Biochemical and Biophysical Research Communications. 37: 744-9. PMID 4900985 DOI: 10.1016/0006-291X(69)90954-1  0.56
1970 Petitclerc C, Lazdunski C, Chappelet D, Moulin A, Lazdunski M. The functional properties of the Zn2(plus)-and Co2(plus)-alkaline phosphatases of Escherichia coli. Labelling of the active site with pyrophosphate, complex formation with arsenate, and reinvestigation of the role of the zinc atoms. European Journal of Biochemistry. 14: 301-8. PMID 4319099 DOI: 10.1111/J.1432-1033.1970.Tb00290.X  0.561
1970 Chappelet D, Lazdunski C, Petitclerc C, Lazdunski M. The Mn2plus-alkaline phosphatase of E. coli. Biochemical and Biophysical Research Communications. 40: 91-6. PMID 4318588 DOI: 10.1016/0006-291X(70)91050-8  0.552
1969 Lazdunski C, Petitclerc C, Lazdunski M. Structure-function relationships for some metalloalkaline phosphatases of E. coli. European Journal of Biochemistry. 8: 510-7. PMID 4978714 DOI: 10.1111/J.1432-1033.1969.Tb00556.X  0.542
1969 Lazdunski C, Lazdunski M. Zn2+ and Co2+-alkaline phosphatases of E. coli. A comparative kinetic study. European Journal of Biochemistry. 7: 294-300. PMID 4885467 DOI: 10.1111/J.1432-1033.1969.TB19606.X  0.464
1966 Lazdunski C, Lazdunski M. Etude cinetique du mecanisme d'action catalytique de la phosphatase alcaline d’Escherichia coli Biochimica Et Biophysica Acta (Bba) - Enzymology and Biological Oxidation. 113: 551-566. DOI: 10.1016/S0926-6593(66)80013-9  0.453
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