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James A. Cowan - Publications

Affiliations: 
Chemistry and Biochemistry Ohio State University, Columbus, Columbus, OH 
Area:
Inorganic and Bioinorganic Chemistry
Website:
https://chemistry.osu.edu/faculty/cowan
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Year Citation  Score
2022 Valer L, Rossetto D, Parkkila T, Sebastianelli L, Guella G, Hendricks AL, Cowan JA, Sang L, Mansy SS. Histidine Ligated Iron-Sulfur Peptides. Chembiochem : a European Journal of Chemical Biology. e202200202. PMID 35674331 DOI: 10.1002/cbic.202200202  0.683
2020 Yu Z, Thompson Z, Behnke SL, Fenk KD, Huang D, Shafaat HS, Cowan JA. Metalloglycosidase Mimics: Oxidative Cleavage of Saccharides Promoted by Multinuclear Copper Complexes under Physiological Conditions. Inorganic Chemistry. 59: 11218-11222. PMID 32799467 DOI: 10.1021/Acs.Inorgchem.0C01193  0.311
2020 Sen S, Hendricks AL, Cowan JA. Cluster exchange reactivity of [2Fe-2S]-bridged heterodimeric BOLA1-GLRX5. The Febs Journal. PMID 32542995 DOI: 10.1111/Febs.15452  0.419
2020 Thompson Z, Cowan JA. Artificial Metalloenzymes: Recent Developments and Innovations in Bioinorganic Catalysis. Small (Weinheim An Der Bergstrasse, Germany). e2000392. PMID 32372559 DOI: 10.1002/Smll.202000392  0.307
2020 Pearson SA, Wachnowsky C, Cowan JA. Defining the mechanism of the mitochondrial Atm1p [2Fe-2S] cluster exporter. Metallomics : Integrated Biometal Science. PMID 32337520 DOI: 10.1039/C9Mt00286C  0.431
2020 Jia M, Sen S, Wachnowsky C, Fidai I, Cowan JA, Wysocki V. Characterization of [2Fe-2S]-Cluster-Bridged Protein Complexes and Reaction Intermediates by use of Robust Native Mass Spectrometric Methods. Angewandte Chemie (International Ed. in English). PMID 32031732 DOI: 10.1002/Anie.201915615  0.429
2019 Lewis BE, Mason Z, Rodrigues AV, Nuth M, Dizin E, Cowan JA, Stemmler TL. Unique roles of iron and zinc binding to the yeast Fe-S cluster scaffold assembly protein "Isu1". Metallomics : Integrated Biometal Science. PMID 31532427 DOI: 10.1039/C9Mt00172G  0.724
2019 Wachnowsky C, Rao B, Sen S, Fries B, Howard CJ, Ottesen JJ, Cowan JA. Reconstitution, characterization, and [2Fe-2S] cluster exchange reactivity of a holo human BOLA3 homodimer. Journal of Biological Inorganic Chemistry : Jbic : a Publication of the Society of Biological Inorganic Chemistry. PMID 31486956 DOI: 10.1007/S00775-019-01713-X  0.43
2019 Wachnowsky C, Hendricks AL, Wesley NA, Ferguson C, Fidai I, Cowan JA. Understanding the Mechanism of [4Fe-4S] Cluster Assembly on Eukaryotic Mitochondrial and Cytosolic Aconitase Inorganic Chemistry. 58: 13686-13695. PMID 31436962 DOI: 10.1021/Acs.Inorgchem.9B01278  0.358
2019 Alexander JL, Thompson Z, Yu Z, Cowan JA. Cu-ATCUN Derivatives of Sub5 Exhibit Enhanced Antimicrobial Activity via Multiple Modes of Action. Acs Chemical Biology. PMID 30742402 DOI: 10.1021/Acschembio.8B01087  0.335
2019 Li D, Agarwal A, Cowan JA. Evaluation of Solvent Accessibility to the [Fe(4)S(4)] Binding Pocket in Native and Tyr19 Mutant High Potential Iron Proteins by (1)H-(15)N HMQC and (19)F NMR Experiments. Inorganic Chemistry. 35: 1121-1125. PMID 11666298 DOI: 10.1021/ic951160s  0.305
2018 Pinkham AM, Yu Z, Cowan JA. Broad-spectrum catalytic metallopeptide inactivators of Zika and West Nile virus NS2B/NS3 proteases. Chemical Communications (Cambridge, England). PMID 30324214 DOI: 10.1039/C8Cc07448H  0.315
2018 Sen S, Rao B, Wachnowsky C, Cowan JA. Cluster exchange reactivity of [2Fe-2S] cluster-bridged complexes of BOLA3 with monothiol glutaredoxins. Metallomics : Integrated Biometal Science. PMID 30137089 DOI: 10.1039/C8Mt00128F  0.414
2018 Olive JA, Cowan JA. Role of the HSPA9/HSC20 chaperone pair in promoting directional human iron-sulfur cluster exchange involving monothiol glutaredoxin 5. Journal of Inorganic Biochemistry. 184: 100-107. PMID 29689452 DOI: 10.1016/J.Jinorgbio.2018.04.007  0.403
2018 Pinkham AM, Yu Z, Cowan JA. Attenuation of West Nile Virus NS2B/NS3 Protease by Amino Terminal Copper and Nickel Bind-ing (ATCUN) Peptides. Journal of Medicinal Chemistry. PMID 29301071 DOI: 10.1021/Acs.Jmedchem.7B01409  0.384
2018 Wachnowsky C, Fidai I, Cowan JA. Iron–sulfur cluster biosynthesis and trafficking – impact on human disease conditions Metallomics. 10: 9-29. PMID 29019354 DOI: 10.1039/C7Mt00180K  0.383
2017 Sen S, Bonfio C, Mansy SS, Cowan JA. Investigation of glutathione-derived electrostatic and hydrogen-bonding interactions and their role in defining Grx5 [2Fe-2S] cluster optical spectra and transfer chemistry. Journal of Biological Inorganic Chemistry : Jbic : a Publication of the Society of Biological Inorganic Chemistry. PMID 29264659 DOI: 10.1007/S00775-017-1525-5  0.807
2017 Wachnowsky C, Liu Y, Yoon T, Cowan JA. Regulation of Human Nfu Activity in Fe-S Cluster Delivery - Characterization of the Interaction between Nfu and the HSPA9/Hsc20 Chaperone Complex. The Febs Journal. PMID 29211945 DOI: 10.1111/Febs.14353  0.637
2017 Alexander JL, Yu Z, Cowan JA. Amino Terminal Copper and Nickel Binding Motif Derivatives of Ovispirin-3 Display Increased Antimicrobial Activity via Lipid Oxidation. Journal of Medicinal Chemistry. 60: 10047-10055. PMID 29172482 DOI: 10.1021/Acs.Jmedchem.7B01117  0.337
2017 Yu Z, Cowan JA. Metal complexes promoting catalytic cleavage of nucleic acids-biochemical tools and therapeutics. Current Opinion in Chemical Biology. 43: 37-42. PMID 29153936 DOI: 10.1016/J.Cbpa.2017.10.029  0.316
2017 Wesley NA, Wachnowsky C, Fidai I, Cowan JA. Understanding the Molecular Basis for Multiple Mitochondrial Dysfunctions Syndrome 1 (MMDS1): Impact of a Disease-Causing Gly189Arg Substitution on NFU1. The Febs Journal. PMID 28906594 DOI: 10.1111/Febs.14271  0.42
2017 Wesley NA, Wachnowsky C, Fidai I, Cowan JA. Analysis of NFU-1 Metallocofactor Binding Site Substitutions: Impacts on Iron-Sulfur Cluster Coordination and Protein Structure and Function. The Febs Journal. PMID 28906593 DOI: 10.1111/Febs.14270  0.429
2017 Wachnowsky C, Cowan JA. In Vitro Studies of Cellular Iron-Sulfur Cluster Biosynthesis, Trafficking, and Transport. Methods in Enzymology. 595: 55-82. PMID 28882208 DOI: 10.1016/Bs.Mie.2017.06.045  0.445
2017 Sen S, Cowan JA. Role of protein-glutathione contacts in defining glutaredoxin-3 [2Fe-2S] cluster chirality, ligand exchange and transfer chemistry. Journal of Biological Inorganic Chemistry : Jbic : a Publication of the Society of Biological Inorganic Chemistry. PMID 28836015 DOI: 10.1007/S00775-017-1485-9  0.436
2017 Cowan JA, Yu Z. Catalytic Metallodrugs: Substrate-Selective Metal Catalysts as Therapeutics. Chemistry (Weinheim An Der Bergstrasse, Germany). PMID 28688119 DOI: 10.1002/Chem.201701714  0.314
2017 Ross MJ, Fidai I, Cowan JA. Analysis of Structure-Activity Relationships Based on the HCV SLIIb IRES RNA-Targeting GGHYRFK-Cu Complex. Chembiochem : a European Journal of Chemical Biology. PMID 28628737 DOI: 10.1002/Cbic.201700228  0.344
2017 Wachnowsky C, Wesley NA, Fidai I, Cowan JA. Understanding the Molecular Basis of Multiple Mitochondrial Dysfunctions Syndrome 1 (MMDS1)-Impact of a Disease-Causing Gly208Cys Substitution on Structure and Activity of NFU1 in the Fe/S Cluster Biosynthetic Pathway. Journal of Molecular Biology. 429: 790-807. PMID 28161430 DOI: 10.1016/J.Jmb.2017.01.021  0.418
2016 Fidai I, Wachnowsky C, Cowan JA. Mapping cellular Fe-S cluster uptake and exchange reactions - divergent pathways for iron-sulfur cluster delivery to human ferredoxins. Metallomics. 8: 1283-1293. PMID 27878189 DOI: 10.1039/C6Mt00193A  0.396
2016 Wachnowsky C, Fidai I, Cowan JA. Cytosolic iron-sulfur cluster transfer-a proposed kinetic pathway for reconstitution of glutaredoxin 3. Febs Letters. PMID 27859051 DOI: 10.1002/1873-3468.12491  0.433
2016 Scintilla S, Bonfio C, Belmonte L, Forlin M, Rossetto D, Li J, Cowan JA, Galliani A, Arnesano F, Assfalg M, Mansy SS. Duplications of an iron-sulphur tripeptide leads to the formation of a protoferredoxin. Chemical Communications (Cambridge, England). PMID 27790655 DOI: 10.1039/C6Cc07912A  0.779
2016 Fidai I, Wachnowsky C, Cowan JA. Glutathione-complexed [2Fe-2S] clusters function in Fe–S cluster storage and trafficking Journal of Biological Inorganic Chemistry. 21: 887-901. PMID 27590019 DOI: 10.1007/S00775-016-1387-2  0.433
2016 Wachnowsky C, Fidai I, Cowan JA. Iron-sulfur cluster exchange reactions mediated by the human Nfu protein. Journal of Biological Inorganic Chemistry. 21: 825-836. PMID 27538573 DOI: 10.1007/S00775-016-1381-8  0.39
2015 Ross MJ, Bradford SS, Cowan JA. Catalytic metallodrugs based on the LaR2C peptide target HCV SLIV IRES RNA. Dalton Transactions (Cambridge, England : 2003). PMID 26583601 DOI: 10.1039/C5Dt02837J  0.68
2014 Fidai I, Hocharoen L, Bradford S, Wachnowsky C, Cowan JA. Inactivation of sortase A mediated by metal ATCUN complexes. Journal of Biological Inorganic Chemistry : Jbic : a Publication of the Society of Biological Inorganic Chemistry. 19: 1327-39. PMID 25217034 DOI: 10.1007/S00775-014-1190-X  0.778
2014 Bradford SS, Ross MJ, Fidai I, Cowan JA. Insight into the recognition, binding, and reactivity of catalytic metallodrugs targeting stem loop IIb of hepatitis C IRES RNA. Chemmedchem. 9: 1275-85. PMID 24756921 DOI: 10.1002/Cmdc.201400070  0.679
2014 Amick J, Schlanger SE, Wachnowsky C, Moseng MA, Emerson CC, Dare M, Luo WI, Ithychanda SS, Nix JC, Cowan JA, Page RC, Misra S. Crystal structure of the nucleotide-binding domain of mortalin, the mitochondrial Hsp70 chaperone. Protein Science : a Publication of the Protein Society. 23: 833-42. PMID 24687350 DOI: 10.1002/Pro.2466  0.608
2014 Bradford SS, Cowan JA. From Traditional Drug Design to Catalytic Metallodrugs: A Brief History of the Use of Metals in Medicine Metallodrugs. 1. DOI: 10.2478/medr-2014-0002  0.643
2014 Luo WI, Cowan JA. The role of mortalin in iron homeostasis Mortalin Biology: Life, Stress and Death. 2147483647: 31-54. DOI: 10.1007/978-94-007-3027-4_3  0.592
2014 Bradford SS, Ross MJ, Fidai I, Cowan JA. Inside Cover: Insight into the Recognition, Binding, and Reactivity of Catalytic Metallodrugs Targeting Stem Loop IIb of Hepatitis C IRES RNA (ChemMedChem 6/2014) Chemmedchem. 9: 1086-1086. DOI: 10.1002/Cmdc.201490021  0.679
2013 Hocharoen L, Joyner JC, Cowan JA. N- versus C-domain selectivity of catalytic inactivation of human angiotensin converting enzyme by lisinopril-coupled transition metal chelates. Journal of Medicinal Chemistry. 56: 9826-36. PMID 24228790 DOI: 10.1021/Jm4009345  0.756
2013 Joyner JC, Cowan JA. Target-directed catalytic metallodrugs. Brazilian Journal of Medical and Biological Research = Revista Brasileira De Pesquisas MéDicas E BiolóGicas / Sociedade Brasileira De BiofíSica ... [Et Al.]. 46: 465-85. PMID 23828584 DOI: 10.1590/1414-431X20133086  0.752
2013 Joyner JC, Keuper KD, Cowan JA. Kinetics and Mechanisms of Oxidative Cleavage of HIV RRE RNA by Rev-Coupled Transition Metal Chelates. Chemical Science (Royal Society of Chemistry : 2010). 4: 1707-1718. PMID 23626900 DOI: 10.1039/C3Sc22135K  0.75
2013 Joyner JC, Hodnick WF, Cowan AS, Tamuly D, Boyd R, Cowan JA. Antimicrobial metallopeptides with broad nuclease and ribonuclease activity. Chemical Communications (Cambridge, England). 49: 2118-20. PMID 23380915 DOI: 10.1039/C3Cc38977D  0.738
2013 Joyner JC, Keuper KD, Cowan JA. Analysis of RNA cleavage by MALDI-TOF mass spectrometry. Nucleic Acids Research. 41: e2. PMID 22941655 DOI: 10.1093/Nar/Gks811  0.723
2012 Qi W, Li J, Chain CY, Pasquevich GA, Pasquevich AF, Cowan JA. Glutathione complexed Fe-S centers. Journal of the American Chemical Society. 134: 10745-8. PMID 22687047 DOI: 10.1021/Ja302186J  0.411
2012 Joyner JC, Keuper KD, Cowan JA. DNA nuclease activity of Rev-coupled transition metal chelates. Dalton Transactions (Cambridge, England : 2003). 41: 6567-78. PMID 22450234 DOI: 10.1039/C2Dt00026A  0.757
2012 Bradford S, Cowan JA. Catalytic metallodrugs targeting HCV IRES RNA. Chemical Communications (Cambridge, England). 48: 3118-20. PMID 22343977 DOI: 10.1039/C2Cc17377H  0.674
2012 Joyner JC, Hocharoen L, Cowan JA. Targeted catalytic inactivation of angiotensin converting enzyme by lisinopril-coupled transition-metal chelates. Journal of the American Chemical Society. 134: 3396-410. PMID 22200082 DOI: 10.1021/Ja208791F  0.773
2011 Joyner JC, Reichfield J, Cowan JA. Factors influencing the DNA nuclease activity of iron, cobalt, nickel, and copper chelates. Journal of the American Chemical Society. 133: 15613-26. PMID 21815680 DOI: 10.1021/Ja2052599  0.759
2011 Joyner JC, Cowan JA. Targeted cleavage of HIV RRE RNA by Rev-coupled transition metal chelates. Journal of the American Chemical Society. 133: 9912-22. PMID 21585196 DOI: 10.1021/Ja203057Z  0.774
2011 Qi W, Cowan JA. Structural, Mechanistic and Coordination Chemistry of Relevance to the Biosynthesis of Iron-Sulfur and Related Iron Cofactors. Coordination Chemistry Reviews. 255: 688-699. PMID 21499539 DOI: 10.1016/J.Ccr.2010.10.016  0.433
2011 Wu SP, Bellei M, Mansy SS, Battistuzzi G, Sola M, Cowan JA. Redox chemistry of the Schizosaccharomyces pombe ferredoxin electron-transfer domain and influence of Cys to Ser substitutions. Journal of Inorganic Biochemistry. 105: 806-11. PMID 21497579 DOI: 10.1016/J.Jinorgbio.2011.03.004  0.745
2011 Qi W, Cowan JA. Mechanism of glutaredoxin-ISU [2Fe-2S] cluster exchange. Chemical Communications (Cambridge, England). 47: 4989-91. PMID 21437321 DOI: 10.1039/C0Cc05079B  0.409
2011 Patwardhan A, Cowan JA. Influence of charge and structure on the coordination chemistry of copper aminoglycosides. Dalton Transactions (Cambridge, England : 2003). 40: 1795-801. PMID 21218243 DOI: 10.1039/C0Dt00704H  0.624
2010 Bellei M, Battistuzzi G, Wu SP, Mansy SS, Cowan JA, Sola M. Control of reduction thermodynamics in [2Fe-2S] ferredoxins Entropy-enthalpy compensation and the influence of surface mutations. Journal of Inorganic Biochemistry. 104: 691-6. PMID 20362339 DOI: 10.1016/J.Jinorgbio.2010.03.001  0.724
2010 Luo WI, Dizin E, Yoon T, Cowan JA. Kinetic and structural characterization of human mortalin. Protein Expression and Purification. 72: 75-81. PMID 20152901 DOI: 10.1016/J.Pep.2010.02.003  0.729
2010 Kondapalli KC, Bencze KZ, Dizin E, Cowan JA, Stemmler TL. NMR assignments of a stable processing intermediate of human frataxin. Biomolecular Nmr Assignments. 4: 61-4. PMID 20108066 DOI: 10.1007/S12104-010-9209-X  0.369
2010 Qi W, Cowan JA. A structural and functional homolog supports a general role for frataxin in cellular iron chemistry. Chemical Communications (Cambridge, England). 46: 719-21. PMID 20087498 DOI: 10.1039/B911975B  0.345
2009 Liu Y, Cowan JA. Iron-sulfur cluster biosynthesis: characterization of a molten globule domain in human NFU. Biochemistry. 48: 7512-8. PMID 19722697 DOI: 10.1021/Bi9002524  0.415
2009 Hocharoen L, Cowan JA. Metallotherapeutics: novel strategies in drug design. Chemistry (Weinheim An Der Bergstrasse, Germany). 15: 8670-6. PMID 19685535 DOI: 10.1002/Chem.200900821  0.775
2009 Huang J, Cowan JA. Iron-sulfur cluster biosynthesis: role of a semi-conserved histidine. Chemical Communications (Cambridge, England). 3071-3. PMID 19462090 DOI: 10.1039/B902676B  0.544
2009 Bradford S, Kawarasaki Y, Cowan JA. Copper.Lys-Gly-His-Lys mediated cleavage of tRNA(Phe): studies of reaction mechanism and cleavage specificity. Journal of Inorganic Biochemistry. 103: 871-5. PMID 19386364 DOI: 10.1016/J.Jinorgbio.2009.03.003  0.695
2009 Nuth M, Cowan JA. Iron-sulfur cluster biosynthesis: characterization of IscU-IscS complex formation and a structural model for sulfide delivery to the [2Fe-2S] assembly site. Journal of Biological Inorganic Chemistry : Jbic : a Publication of the Society of Biological Inorganic Chemistry. 14: 829-39. PMID 19308466 DOI: 10.1007/S00775-009-0495-7  0.736
2009 Liu Y, Qi W, Cowan JA. Iron-sulfur cluster biosynthesis: functional characterization of the N- and C-terminal domains of human NFU. Biochemistry. 48: 973-80. PMID 19146390 DOI: 10.1021/Bi801645Z  0.394
2008 Huang J, Dizin E, Cowan JA. Mapping iron binding sites on human frataxin: implications for cluster assembly on the ISU Fe-S cluster scaffold protein. Journal of Biological Inorganic Chemistry : Jbic : a Publication of the Society of Biological Inorganic Chemistry. 13: 825-36. PMID 18425540 DOI: 10.1007/S00775-008-0369-4  0.565
2008 Gokhale NH, Bradford S, Cowan JA. Catalytic inactivation of human carbonic anhydrase I by a metallopeptide-sulfonamide conjugate is mediated by oxidation of active site residues. Journal of the American Chemical Society. 130: 2388-9. PMID 18251475 DOI: 10.1021/Ja0778038  0.687
2007 Liu Y, Cowan JA. Iron sulfur cluster biosynthesis. Human NFU mediates sulfide delivery to ISU in the final step of [2Fe-2S] cluster assembly. Chemical Communications (Cambridge, England). 3192-4. PMID 17653385 DOI: 10.1039/B704928E  0.421
2007 Gokhale NH, Bradford S, Cowan JA. Stimulation and oxidative catalytic inactivation of thermolysin by copper.Cys-Gly-His-Lys. Journal of Biological Inorganic Chemistry : Jbic : a Publication of the Society of Biological Inorganic Chemistry. 12: 981-7. PMID 17618468 DOI: 10.1007/S00775-007-0270-6  0.708
2007 Jin Y, Lewis MA, Gokhale NH, Long EC, Cowan JA. Influence of stereochemistry and redox potentials on the single- and double-strand DNA cleavage efficiency of Cu(II) and Ni(II) Lys-Gly-His-derived ATCUN metallopeptides. Journal of the American Chemical Society. 129: 8353-61. PMID 17552522 DOI: 10.1021/Ja0705083  0.351
2007 Bencze KZ, Yoon T, Millán-Pacheco C, Bradley PB, Pastor N, Cowan JA, Stemmler TL. Human frataxin: iron and ferrochelatase binding surface. Chemical Communications (Cambridge, England). 1798-800. PMID 17476391 DOI: 10.1039/B703195E  0.59
2007 Jin Y, Cowan JA. Cellular activity of Rev response element RNA targeting metallopeptides. Journal of Biological Inorganic Chemistry : Jbic : a Publication of the Society of Biological Inorganic Chemistry. 12: 637-44. PMID 17356872 DOI: 10.1007/S00775-007-0221-2  0.345
2007 Yoon T, Dizin E, Cowan JA. N-terminal iron-mediated self-cleavage of human frataxin: regulation of iron binding and complex formation with target proteins. Journal of Biological Inorganic Chemistry : Jbic : a Publication of the Society of Biological Inorganic Chemistry. 12: 535-42. PMID 17285345 DOI: 10.1007/S00775-007-0205-2  0.615
2007 Wu SP, Cowan JA. Iron-sulfur cluster stability. Kinetics and mechanism of ligand-promoted cluster degradation. Chemical Communications (Cambridge, England). 82-4. PMID 17279268 DOI: 10.1039/B610665J  0.579
2006 Chen CA, Cowan JA. Characterization of Saccharomyces cerevisiae Atm1p: functional studies of an ABC7 type transporter. Biochimica Et Biophysica Acta. 1760: 1857-65. PMID 16963188 DOI: 10.1016/j.bbagen.2006.08.002  0.44
2006 Gokhale NH, Cowan JA. Metallopeptide-promoted inactivation of angiotensin-converting enzyme and endothelin-converting enzyme 1: Toward dual-action therapeutics. Journal of Biological Inorganic Chemistry : Jbic : a Publication of the Society of Biological Inorganic Chemistry. 11: 937-47. PMID 16874470 DOI: 10.1007/S00775-006-0145-2  0.376
2005 Gokhale NH, Cowan JA. Inactivation of human angiotensin converting enzyme by copper peptide complexes containing ATCUN motifs. Chemical Communications (Cambridge, England). 5916-8. PMID 16317474 DOI: 10.1039/B511081E  0.334
2005 Wu SP, Mansy SS, Cowan JA. Iron-sulfur cluster biosynthesis. Molecular chaperone DnaK promotes IscU-bound [2Fe-2S] cluster stability and inhibits cluster transfer activity. Biochemistry. 44: 4284-93. PMID 15766257 DOI: 10.1021/Bi0483007  0.739
2004 Mansy SS, Cowan JA. Iron-sulfur cluster biosynthesis: toward an understanding of cellular machinery and molecular mechanism. Accounts of Chemical Research. 37: 719-25. PMID 15379587 DOI: 10.1021/Ar0301781  0.712
2004 Yoon T, Cowan JA. Frataxin-mediated iron delivery to ferrochelatase in the final step of heme biosynthesis. The Journal of Biological Chemistry. 279: 25943-6. PMID 15123683 DOI: 10.1074/Jbc.C400107200  0.613
2004 Venturoli G, Mamedov MD, Mansy SS, Musiani F, Strocchi M, Francia F, Semenov AY, Cowan JA, Ciurli S. Electron transfer from HiPIP to the photooxidized tetraheme cytochrome subunit of Allochromatium vinosum reaction center: new insights from site-directed mutagenesis and computational studies. Biochemistry. 43: 437-45. PMID 14717598 DOI: 10.1021/Bi035384V  0.67
2004 Mansy SS, Wu SP, Cowan JA. Iron-sulfur cluster biosynthesis: biochemical characterization of the conformational dynamics of Thermotoga maritima IscU and the relevance for cellular cluster assembly. The Journal of Biological Chemistry. 279: 10469-75. PMID 14688265 DOI: 10.1074/Jbc.M312051200  0.729
2003 Chen CA, Cowan JA. Characterization of the soluble domain of the ABC7 type transporter Atm1. The Journal of Biological Chemistry. 278: 52681-8. PMID 14514697 DOI: 10.1074/Jbc.M306472200  0.516
2003 Bertini I, Cowan JA, Del Bianco C, Luchinat C, Mansy SS. Thermotoga maritima IscU. Structural characterization and dynamics of a new class of metallochaperone. Journal of Molecular Biology. 331: 907-24. PMID 12909018 DOI: 10.1016/S0022-2836(03)00768-X  0.689
2003 Yoon T, Cowan JA. Iron-sulfur cluster biosynthesis. Characterization of frataxin as an iron donor for assembly of [2Fe-2S] clusters in ISU-type proteins. Journal of the American Chemical Society. 125: 6078-84. PMID 12785837 DOI: 10.1021/ja027967i  0.6
2003 Wu SP, Cowan JA. Iron-sulfur cluster biosynthesis. A comparative kinetic analysis of native and Cys-substituted ISA-mediated [2Fe-2S]2+ cluster transfer to an apoferredoxin target. Biochemistry. 42: 5784-91. PMID 12741836 DOI: 10.1021/Bi026939+  0.562
2003 Cowan JA. Bioinorganic Chemistry: A Short Course. Rosette M. Roat-Malone. Hoboken, NJ: Wiley-Interscience, A John Wiley & Sons Inc. Publication, 2002, 366 pp., $89.95, softcover. ISBN 0-471-15976-X. Clinical Chemistry. 49: 1565-1566. DOI: 10.1373/49.9.1565  0.344
2002 Nuth M, Yoon T, Cowan JA. Iron-sulfur cluster biosynthesis: characterization of iron nucleation sites for assembly of the [2Fe-2S]2+ cluster core in IscU proteins. Journal of the American Chemical Society. 124: 8774-5. PMID 12137512 DOI: 10.1021/Ja0264596  0.771
2002 Chen CA, Cowan JA. In vivo cleavage of a target RNA by copper kanamycin A. Direct observation by a fluorescence assay. Chemical Communications (Cambridge, England). 196-7. PMID 12120364 DOI: 10.1039/B108439A  0.479
2002 Wu SP, Wu G, Surerus KK, Cowan JA. Iron-sulfur cluster biosynthesis. Kinetic analysis of [2Fe-2S] cluster transfer from holo ISU to apo Fd: role of redox chemistry and a conserved aspartate. Biochemistry. 41: 8876-85. PMID 12102630 DOI: 10.1021/Bi0256781  0.578
2002 Battistuzzi G, Borsari M, Cowan JA, Ranieri A, Sola M. Control of cytochrome C redox potential: axial ligation and protein environment effects. Journal of the American Chemical Society. 124: 5315-24. PMID 11996572 DOI: 10.1021/Ja017479V  0.351
2002 Wu G, Mansy SS, Hemann C, Hille R, Surerus KK, Cowan JA. Iron-sulfur cluster biosynthesis: characterization of Schizosaccharomyces pombe Isa1. Journal of Biological Inorganic Chemistry : Jbic : a Publication of the Society of Biological Inorganic Chemistry. 7: 526-32. PMID 11941510 DOI: 10.1007/S00775-001-0330-2  0.702
2002 Wu G, Mansy SS, Wu Sp SP, Surerus KK, Foster MW, Cowan JA. Characterization of an iron-sulfur cluster assembly protein (ISU1) from Schizosaccharomyces pombe. Biochemistry. 41: 5024-32. PMID 11939799 DOI: 10.1021/Bi016073S  0.709
2002 Mansy SS, Wu G, Surerus KK, Cowan JA. Iron-sulfur cluster biosynthesis. Thermatoga maritima IscU is a structured iron-sulfur cluster assembly protein Journal of Biological Chemistry. 277: 21397-21404. PMID 11934893 DOI: 10.1074/Jbc.M201439200  0.677
2002 Mansy SS, Xiong Y, Hemann C, Hille R, Sundaralingam M, Cowan JA. Crystal structure and stability studies of C77S HiPIP: a serine ligated [4Fe-4S] cluster. Biochemistry. 41: 1195-201. PMID 11802718 DOI: 10.1021/Bi011811Y  0.669
2001 Sau AK, Chen CA, Cowan JA, Mazumdar S, Mitra S. Steady-state and time-resolved fluorescence studies on wild type and mutant chromatium vinosum high potential iron proteins: holo- and apo-forms. Biophysical Journal. 81: 2320-30. PMID 11566801 DOI: 10.1016/S0006-3495(01)75878-X  0.539
2001 Puapaiboon U, Jai-nhuknan J, Cowan JA. Characterization of a multi-functional metal-mediated nuclease by MALDI-TOF mass spectrometry Nucleic Acids Research. 29: 3652-3656. PMID 11522836 DOI: 10.1093/Nar/29.17.3652  0.307
2001 Sreedhara A, Cowan JA. Catalytic hydrolysis of DNA by metal ions and complexes Journal of Biological Inorganic Chemistry. 6: 337-347. PMID 11372193 DOI: 10.1007/S007750100209  0.331
2001 Foster MW, Bian S, Surerus KK, Cowan JA. Elucidation of a [4Fe-4S] cluster degradation pathway: Rapid kinetic studies of the degradation of Chromatium vinosum HiPIP Journal of Biological Inorganic Chemistry. 6: 266-274. PMID 11315562 DOI: 10.1007/S007750000196  0.424
2001 Sreedhara A, Cowan JA. Targeted site-specific cleavage of HIV-1 viral Rev responsive element by copper aminoglycosides Journal of Biological Inorganic Chemistry. 6: 166-172. PMID 11293410 DOI: 10.1007/S007750000187  0.318
2001 Patwardhan A, Cowan JA. Highly specific oxidative damage of double-strand DNA by copper aminoglycosides Chemical Communications. 1490-1491. DOI: 10.1039/B103789G  0.562
2000 Cowan JA, Ohyama T, Wang D, Natarajan K. Recognition of a cognate RNA aptamer by neomycin B: Quantitative evaluation of hydrogen bonding and electrostatic interactions Nucleic Acids Research. 28: 2935-2942. PMID 10908357 DOI: 10.1093/Nar/28.15.2935  0.32
2000 Cowan JA, Ohyama T, Howard K, Rausch JW, Cowan SM, Le Grice SF. Metal-ion stoichiometry of the HIV-1 RT ribonuclease H domain: evidence for two mutually exclusive sites leads to new mechanistic insights on metal-mediated hydrolysis in nucleic acid biochemistry. Journal of Biological Inorganic Chemistry : Jbic : a Publication of the Society of Biological Inorganic Chemistry. 5: 67-74. PMID 10766438 DOI: 10.1007/S007750050009  0.343
2000 Sreedhara A, Freed JD, Cowan JA. Efficient inorganic deoxyribonucleases. Greater than 50-million-fold rate enhancement in enzyme-like DNA cleavage Journal of the American Chemical Society. 122: 8814-8824. DOI: 10.1021/Ja994411V  0.309
2000 Foster MW, Mansy SS, Hwang J, Penner-Hahn JE, Surerus KK, Cowan JA. A mutant human IscU protein contains a stable [2Fe-2S]2+ center of possible functional significance [21] Journal of the American Chemical Society. 122: 6805-6806. DOI: 10.1021/Ja000800+  0.662
2000 Chen CA, Chi-Hung L, Cowan JA. Functional role of a conserved tryptophan residue of Chromatium vinosum high potential iron protein Inorganica Chimica Acta. 300: 91-95. DOI: 10.1016/S0020-1693(99)00532-0  0.57
1999 Battistuzzi G, Borsari M, Cowan JA, Eicken C, Loschi L, Sola M. Redox chemistry and acid-base equilibria of mitochondrial plant cytochromes c. Biochemistry. 38: 5553-62. PMID 10220343 DOI: 10.1021/Bi982429X  0.307
1999 Foster MW, Cowan JA. Chemistry of nitric oxide with protein-bound iron sulfur centers. Insights on physiological reactivity Journal of the American Chemical Society. 121: X. DOI: 10.1021/Ja9901056  0.433
1999 Bian S, Cowan JA. Protein-bound iron-sulfur centers. Form, function, and assembly Coordination Chemistry Reviews. 190: 1049-1066. DOI: 10.1016/S0010-8545(99)00157-5  0.348
1998 Suga H, Cowan JA, Szostak JW. Unusual metal ion catalysis in an acyl-transferase ribozyme. Biochemistry. 37: 10118-25. PMID 9665717 DOI: 10.1021/Bi980432A  0.528
1998 Natarajan K, Cowan JA. Solution structure of a synthetic lytic peptide: the perforin amino terminus. Chemistry & Biology. 5: 147-54. PMID 9545423 DOI: 10.1016/S1074-5521(98)90059-X  0.3
1998 Cowan JA. Magnesium activation of nuclease enzymes—the importance of water Inorganica Chimica Acta. 24-27. DOI: 10.1016/S0020-1693(98)00073-5  0.342
1998 Black CB, Cowan JA. A critical evaluation of metal-promoted Klenow 3′-5′ exonuclease activity: calorimetric and kinetic analyses support a one-metal-ion mechanism Journal of Biological Inorganic Chemistry. 3: 292-299. DOI: 10.1007/S007750050234  0.326
1997 Bertini I, Cowan JA, Luchinat C, Natarajan K, Piccioli M. Characterization of a partially unfolded high potential iron protein. Biochemistry. 36: 9332-9. PMID 9235975 DOI: 10.1021/Bi970810W  0.404
1997 Black CB, Cowan JA. Inert chromium and cobalt complexes as probes of magnesium-dependent enzymes. Evaluation of the mechanistic role of the essential metal cofactor in Escherichia coli exonuclease III. European Journal of Biochemistry. 243: 684-9. PMID 9057832 DOI: 10.1111/J.1432-1033.1997.00684.X  0.333
1997 Natarajan K, Cowan JA. Identification of a Key Intermediate of Relevance to Iron−Sulfur Cluster Biosynthesis. Mechanism of Cluster Assembly and Implications for Protein Folding Journal of the American Chemical Society. 119: 4082-4083. DOI: 10.1021/Ja9639729  0.348
1997 Cowan JA. Metal-mediated hydrolysis of biological phosphate esters: A critical analysis of the essential metal ion stoichiometry for magnesium-dependent nuclease activation Journal of Biological Inorganic Chemistry. 2: 168-176. DOI: 10.1007/S007750050121  0.328
1996 Bian S, Hemann CF, Hille R, Cowan JA. Characterization of an autoreduction pathway for the [Fe4S4]3+ cluster of mutant Chromatium vinosum high-potential iron proteins. Site-directed mutagenesis studies to probe the role of phenylalanine 66 in defining the stability of the [Fe4S4] center provide evidence for oxidative degradation via a [Fe3S4] cluster Biochemistry. 35: 14544-14552. PMID 8931551 DOI: 10.1021/Bi961658L  0.427
1996 Soriano A, Li D, Bian S, Agarwal A, Cowan JA. Factors influencing redox thermodynamics and electron self-exchange for the [Fe4S4] cluster in Chromatium vinosum high potential iron protein: the role of core aromatic residues in defining cluster redox chemistry. Biochemistry. 35: 12479-86. PMID 8823183 DOI: 10.1021/Bi960974X  0.428
1996 Agarwal A, Li D, Cowan JA. Influence of Oxygen Ligation on [Fe4S4] Cluster Properties. Characterization of the Cys77Ser Mutant ofChromatium vinosumHiPIP Journal of the American Chemical Society. 118: 927-928. DOI: 10.1021/Ja953447U  0.303
1996 Li D, Soriano A, Cowan JA. 19F NMR Studies of Fluorine-LabeledChromatium vinosumHigh-Potential Iron Protein† Inorganic Chemistry. 35: 1980-1987. DOI: 10.1021/Ic951159T  0.341
1996 Soriano A, Cowan J. Phenylalanine 48 of Chromatium vinosum high potential iron protein is essential for stability of the oxidized [Fe4S4] cluster. Site-directed mutagenesis and NMR studies as a probe of cluster chemistry Inorganica Chimica Acta. 251: 285-290. DOI: 10.1016/S0020-1693(96)05281-4  0.421
1996 Man Lui S, Cowan J. Optical and EPR characterization of Desulfovibrio vulgaris (Hildenborough) sulfite reductase and ligand adducts Inorganica Chimica Acta. 242: 25-30. DOI: 10.1016/0020-1693(95)04845-6  0.322
1996 Aono S, Bertini I, Cowan JA, Luchinat C, Rosato A, Viezzoli MS. 1H NMR studies of the Fe7S8 ferredoxin from Bacillus schlegelii: a further attempt to understand Fe3S4 clusters Jbic Journal of Biological Inorganic Chemistry. 1: 523-528. DOI: 10.1007/S007750050087  0.359
1996 Ohyama T, Cowan JA. Influence of monovalent cations on magnesium binding to poly-RNA by solution titration calorimetry: an analysis of the salt dependence of binding enthalpies and entropies Journal of Biological Inorganic Chemistry. 1: 111-116. DOI: 10.1007/S007750050029  0.309
1995 Agarwal A, Li D, Cowan JA. Role of aromatic residues in stabilization of the [Fe4S4] cluster in high-potential iron proteins (HiPIPs): physical characterization and stability studies of Tyr-19 mutants of Chromatium vinosum HiPIP. Proceedings of the National Academy of Sciences of the United States of America. 92: 9440-4. PMID 7568150 DOI: 10.1073/Pnas.92.21.9440  0.385
1994 Huang HW, Cowan JA. Metallobiochemistry of the magnesium ion - Characterization of the essential metal-binding site in Escherichia coli ribonuclease H European Journal of Biochemistry. 219: 253-260. PMID 8306992 DOI: 10.1111/J.1432-1033.1994.Tb19936.X  0.359
1994 Wolfe BM, Lui SM, Cowan JA. Desulfoviridin, a multimeric-dissimilatory sulfite reductase from Desulfovibrio vulgaris (Hildenborough). Purification, characterization, kinetics and EPR studies European Journal of Biochemistry. 223: 79-89. PMID 8033912 DOI: 10.1111/J.1432-1033.1994.Tb18968.X  0.361
1993 Agarwal A, Tan J, Eren M, Tevelev A, Lui SM, Cowan JA. Synthesis, Cloning and Expression of a Synthetic Gene for High Potential Iron Protein from Chromatium vinosum Biochemical and Biophysical Research Communications. 197: 1357-1362. PMID 7916611 DOI: 10.1006/Bbrc.1993.2626  0.345
1993 Cowan JA. Metallobiochemistry of RNA. Co(NH3)6(3+) as a probe for Mg2+(aq) binding sites. Journal of Inorganic Biochemistry. 49: 171-5. PMID 7679435 DOI: 10.1016/0162-0134(93)80002-Q  0.341
1993 Lui SM, Soriano A, Cowan JA. Enzymic reduction of inorganic anions. Pre-steady-state kinetic analysis of the dissimilatory sulfite reductase (desulfoviridin) from Desulfovibrio vulgaris (Hildenborough). Mechanistic implications Journal of the American Chemical Society. 115: 10483-10486. DOI: 10.1021/Ja00076A003  0.307
1992 Sola M, Cowan JA. Assignment of heme resonances in the 1H NMR spectrum of oxidized Desulfovibrio vulgaris (Hildenborough) cytochrome c3 Inorganica Chimica Acta. 202: 241-251. DOI: 10.1016/S0020-1693(00)86841-3  0.326
1991 Tan J, Cowan JA. Enzymatic redox chemistry: a proposed reaction pathway for the six-electron reduction of SO3(2-) to S2- by the assimilatory-type sulfite reductase from Desulfovibrio vulgaris (Hildenborough). Biochemistry. 30: 8910-7. PMID 1888748 DOI: 10.1021/Bi00100A027  0.362
1991 Reid SS, Cowan JA. Metallobiochemistry of a ribosomal RNA. A possible role for Na+ and K+ in the regulation of Mg2+ binding sites on Escherichia coli 5S rRNA : implications for activity Journal of the American Chemical Society. 113: 673-675. DOI: 10.1021/Ja00002A045  0.317
1991 Borsari M, Sola M, Cowan JA. Polarographic studies of Chromatium vinosum high-potential iron protein Bioelectrochemistry and Bioenergetics. 26: 123-129. DOI: 10.1016/0302-4598(91)87039-J  0.349
1990 Cowan JA, Sola M. 1H NMR studies of oxidized high-potential iron protein from Chromatium vinosum. Nuclear Overhauser effect measurements. Biochemistry. 29: 5633-7. PMID 2386791 DOI: 10.1021/Bi00475A031  0.313
1990 Reid SS, Cowan JA. Biostructural chemistry of magnesium ion: characterization of the weak binding sites on tRNA(Phe)(yeast). Implications for conformational change and activity. Biochemistry. 29: 6025-32. PMID 2383570 DOI: 10.1021/Bi00477A021  0.322
1989 Sola M, Cowan JA, Gray HB. 1H NMR characterization of Chromatium gracile high-potential iron protein and its ruthenium-modified derivatives. Modulation of the reduction potentials in low- and high-potential [Fe4S4] ferredoxins. Biochemistry. 28: 5261-8. PMID 2765533 DOI: 10.1021/Bi00438A051  0.452
1988 Cowan JA, Upmacis RK, Beratan DN, Onuchic JN, Gray HB. Long-range electron transfer in myoglobin. Annals of the New York Academy of Sciences. 550: 68-84. PMID 3245652 DOI: 10.1111/J.1749-6632.1988.Tb35324.X  0.323
1986 Cowan JA, Sanders JK. Reductive demetallation of porphyrins: Evidence for peripheral and axial modes of reduction Tetrahedron Letters. 27: 1201-1204. DOI: 10.1016/S0040-4039(00)84216-1  0.485
Low-probability matches (unlikely to be authored by this person)
2019 Yu Z, Fenk K, Huang D, Sen S, Cowan JA. Rapid Telomere Reduction in Cancer Cells Induced by G-Quadruplex-Targeting Copper Complexes. Journal of Medicinal Chemistry. PMID 31026396 DOI: 10.1021/Acs.Jmedchem.9B00215  0.299
1993 Tevelev A, Black C, Cowan J. Ribonuclease H. A magnesium-dependent endonuclease. Role of Mg2+ in substrate binding and evidence for a distinct polynucleotide binding regulatory domain. Journal of Inorganic Biochemistry. 51: 541. DOI: 10.1016/0162-0134(93)85567-R  0.298
1995 Soriano A, Cowan JA. Sulfite Reductase: Active Site Residues are "Noncatalytic". Comparison of Reaction Energetics for Enzyme- and Siroheme-Catalyzed Reduction of Inorganic Substrates. Journal of the American Chemical Society. 117: 4724-4725. DOI: 10.1021/Ja00121A038  0.294
2015 Li J, Cowan JA. Glutathione-coordinated [2Fe-2S] cluster: a viable physiological substrate for mitochondrial ABCB7 transport. Chemical Communications (Cambridge, England). 51: 2253-5. PMID 25556595 DOI: 10.1039/c4cc09175b  0.292
2019 Cowan JA. Metal Activation of Enzymes in Nucleic Acid Biochemistry. Chemical Reviews. 98: 1067-1088. PMID 11848925 DOI: 10.1021/Cr960436Q  0.291
2000 Puapaiboon U, Jai-nhuknan J, Cowan JA. Rapid and direct sequencing of double-stranded DNA using exonuclease III and MALDI-TOF MS Analytical Chemistry. 72: 3338-3341. PMID 10939408 DOI: 10.1021/Ac000181N  0.291
2002 Maguire ME, Cowan JA. Magnesium chemistry and biochemistry. Biometals : An International Journal On the Role of Metal Ions in Biology, Biochemistry, and Medicine. 15: 203-10. PMID 12206387 DOI: 10.1023/A:1016058229972  0.289
2014 Qi W, Li J, Cowan JA. A structural model for glutathione-complexed iron-sulfur cluster as a substrate for ABCB7-type transporters. Chemical Communications (Cambridge, England). 50: 3795-8. PMID 24584132 DOI: 10.1039/c3cc48239a  0.289
1991 Jou R, Cowan JA. Ribonuclease H activation by inert transition-metal complexes. Mechanistic probes for metallocofactors: insights on the metallobiochemistry of divalent magnesium ion Journal of the American Chemical Society. 113: 6685-6686. DOI: 10.1021/Ja00017A056  0.288
1990 Tan JA, Cowan JA. Coordination and redox properties of a novel triheme cytochrome from Desulfovibrio vulgaris (Hildenborough). Biochemistry. 29: 4886-92. PMID 2163671 DOI: 10.1021/Bi00472A019  0.287
1998 Liu J, Meyers EA, Cowan JA, Shore SG. The cyanate ion as a bridging ligand between lanthanide and transition metals. Formation of one-dimensional extended arrays {(DMF)6Ln2Ni(NCO)8}∞ (Ln = Sm, Eu) and monomeric complexes (DMF)8Ln2Ni(NCO)8 (Ln = Sm, Eu) with three bridging cyanate ligands Chemical Communications. 2043-2044. DOI: 10.1039/A804348E  0.287
1997 Rochel N, Cowan JA. Dependence of the lytic activity of the N-terminal domain of human perforin on membrane lipid composition--implications for T-cell self-preservation. European Journal of Biochemistry. 249: 223-31. PMID 9363773 DOI: 10.1111/J.1432-1033.1997.00223.X  0.286
2017 Yu Z, Cowan JA. Frontispiece: Catalytic Metallodrugs: Substrate-Selective Metal Catalysts as Therapeutics Chemistry - a European Journal. 23. DOI: 10.1002/Chem.201785762  0.285
2009 Cowan JA. Iron sulfur cluster biosynthesis: Scaffold and donor proteins, and mechanistic insights Acs Symposium Series. 1012: 3-16. DOI: 10.1021/bk-2009-1012.ch001  0.285
1997 Bertini I, Cowan J, Luchinat C, Natarajan K, Piccioli M. Folding/unfolding of FeS proteins Journal of Inorganic Biochemistry. 67: 249. DOI: 10.1016/S0162-0134(97)80121-3  0.285
2020 Parveen S, Cowan JA, Yu Z, Arjmand F. Enantiomeric copper based anticancer agents promoting sequence-selective cleavage of G-quadruplex telomeric DNA and non-random cleavage of plasmid DNA. Metallomics : Integrated Biometal Science. PMID 32400839 DOI: 10.1039/D0Mt00084A  0.282
2020 Arjmand F, Sharma S, Parveen S, Toupet L, Yu Z, Cowan JA. Copper(ii) l/d-valine-(1,10-phen) complexes target human telomeric G-quadruplex motifs and promote site-specific DNA cleavage and cellular cytotoxicity. Dalton Transactions (Cambridge, England : 2003). PMID 32638779 DOI: 10.1039/D0Dt01527J  0.278
2013 Qi W, Li J, Chain CY, Pasquevich GA, Pasquevich AF, Cowan JA. Glutathione-complexed iron-sulfur clusters. Reaction intermediates and evidence for a template effect promoting assembly and stability. Chemical Communications (Cambridge, England). 49: 6313-5. PMID 23739324 DOI: 10.1039/c3cc43620a  0.277
1994 Cowan JA, Huang HW, Hsu LY. Sequence selective coordination of Mg2+(aq) to DNA. Journal of Inorganic Biochemistry. 52: 121-9. PMID 8254332 DOI: 10.1016/0162-0134(93)85028-7  0.276
2015 Li J, Pearson SA, Fenk KD, Cowan JA. Glutathione-coordinated [2Fe-2S] cluster is stabilized by intramolecular salt bridges. Journal of Biological Inorganic Chemistry : Jbic : a Publication of the Society of Biological Inorganic Chemistry. PMID 26468125 DOI: 10.1007/s00775-015-1301-3  0.276
1998 Ohyama T, Cowan JA. Anion coordination by aminoglycosides: structural and charge effects Chemical Communications. 467-468. DOI: 10.1039/A708868J  0.271
2017 Yu Z, Cowan JA. Design of Artificial Glycosidases: Metallopeptides that Remove H Antigen from Human Erythrocytes. Angewandte Chemie (International Ed. in English). PMID 28128528 DOI: 10.1002/Anie.201612079  0.269
2002 Sreedhara A, Cowan JA. Structural and catalytic roles for divalent magnesium in nucleic acid biochemistry. Biometals : An International Journal On the Role of Metal Ions in Biology, Biochemistry, and Medicine. 15: 211-23. PMID 12206388 DOI: 10.1023/A:1016070614042  0.267
2000 Foster MW, Yuvaniyami P, Cowan JA, Agar JN, Cash VL, Johnson MK, Dean DR. NifS-directed assembly of a transient [2Fe-2S] cluster within the NifU protein Chemtracts. 13: 316-319.  0.263
2001 Cowan JA. Chemical nucleases Current Opinion in Chemical Biology. 5: 634-642. PMID 11738172 DOI: 10.1016/S1367-5931(01)00259-9  0.258
2013 Li J, Ding S, Cowan JA. Thermodynamic and structural analysis of human NFU conformational chemistry. Biochemistry. 52: 4904-13. PMID 23796308 DOI: 10.1021/bi400320s  0.257
1993 Wolfe B, Soriano A, Lui S, Cowan J. Mechanistic studies of enzymatic sulfite and nitrite reduction. Evaluation of kinetic barriers and characterization of reaction intermediates. Journal of Inorganic Biochemistry. 51: 45. DOI: 10.1016/0162-0134(93)85083-K  0.251
1994 Lui SM, Liang W, Soriano A, Cowan JA. Enzymic Reduction of Inorganic Anions. Variable-Temperature Steady-State and Pre-Steady-State Kinetics Experiments to Map the Energy Profile of an Enzymic Multielectron Redox Reaction. Application to the Dissimilatory Sulfite Reductase from Desulfovibrio vulgaris (Hildenborough) Journal of the American Chemical Society. 116: 4531-4536. DOI: 10.1021/Ja00090A001  0.246
1994 Lui SM, Cowan JA. Studies of the Electronic and Dynamic Properties of High-Potential Iron Proteins by Substitution with Non-Natural Amino Acids. 3-Fluorotyrosine-Modified Chromatium vinosum High-Potential Iron Protein Journal of the American Chemical Society. 116: 4483-4484. DOI: 10.1021/ja00089a050  0.226
1990 Cowan JA, Sola M. Proton NMR hyperfine-shifted resonances from the exchange-coupled Fe4S4-siroheme of the assimilatory sulfite reductase from Desulfovibrio vulgaris (Hildenborough) Inorganic Chemistry. 29: 2176-2179. DOI: 10.1021/Ic00336A028  0.22
2003 Babu CS, Dudev T, Casareno R, Cowan JA, Lim C. A combined experimental and theoretical study of divalent metal ion selectivity and function in proteins: application to E. coli ribonuclease H1. Journal of the American Chemical Society. 125: 9318-28. PMID 12889961 DOI: 10.1021/ja034956w  0.215
2005 Jin Y, Cowan JA. DNA cleavage by copper-ATCUN complexes. Factors influencing cleavage mechanism and linearization of dsDNA. Journal of the American Chemical Society. 127: 8408-15. PMID 15941274 DOI: 10.1021/ja0503985  0.211
2006 Jin Y, Cowan JA. Targeted cleavage of HIV rev response element RNA by metallopeptide complexes. Journal of the American Chemical Society. 128: 410-1. PMID 16402818 DOI: 10.1021/ja055272m  0.208
1994 Lui SM, Soriano A, Cowan JA. Electronic properties of the dissimilatory sulphite reductase from Desulfovibrio vulgaris (Hildenborough): Comparative studies of optical spectra and relative reduction potentials for the [Fe4S4]-sirohaem prosthetic centres Biochemical Journal. 304: 441-447. PMID 7998978 DOI: 10.1042/bj3040441  0.194
1997 Hampel A, Cowan JA. A unique mechanism for RNA catalysis: the role of metal cofactors in hairpin ribozyme cleavage. Chemistry & Biology. 4: 513-7. PMID 9263639 DOI: 10.1016/S1074-5521(97)90323-9  0.19
2018 Alexander JL, Thompson Z, Cowan JA. Antimicrobial Metallopeptides. Acs Chemical Biology. PMID 29390186 DOI: 10.1021/acschembio.7b00989  0.19
2002 Maguire ME, Cowan JA. Preface - Introduction: Magnesium in the new millenium Biometals. 15: 201. DOI: 10.1023/A:1016050027246  0.187
1991 Tan J, Helms LR, Swenson RP, Cowan JA. Primary structure of the assimilatory-type sulfite reductase from Desulfovibrio vulgaris (Hildenborough): cloning and nucleotide sequence of the reductase gene. Biochemistry. 30: 9900-7. PMID 1911781 DOI: 10.1021/bi00105a013  0.186
2004 Vicic DA, Anderson TJ, Cowan JA, Schultz AJ. Synthesis, structure, and reactivity of a dinuclear metal complex with linear M-H-M bonding. Journal of the American Chemical Society. 126: 8132-3. PMID 15225051 DOI: 10.1021/Ja047956K  0.171
1995 Huang HW, Li D, Cowan JA. Biostructural chemistry of magnesium. Regulation of mithramycin-DNA interactions by Mg2+ coordination Biochimie. 77: 729-738. PMID 8789464 DOI: 10.1016/0300-9084(96)88190-9  0.168
1995 Li D, Cottrell CE, Cowan JA. 15N resonance assignments of oxidized and reduced Chromatium vinosum high-potential iron protein. Journal of Protein Chemistry. 14: 115-26. PMID 7576079 DOI: 10.1007/BF01980323  0.167
2015 Yu Z, Han M, Cowan JA. Toward the design of a catalytic metallodrug: selective cleavage of G-quadruplex telomeric DNA by an anticancer copper-acridine-ATCUN complex. Angewandte Chemie (International Ed. in English). 54: 1901-5. PMID 25504651 DOI: 10.1002/anie.201410434  0.156
2020 Arjmand F, Sharma S, Parveen S, Toupet L, Yu Z, Cowan JA. Correction: Copper(ii) l/d-valine-(1,10-phen) complexes target human telomeric G-quadruplex motifs and promote site-specific DNA cleavage and cellular cytotoxicity. Dalton Transactions (Cambridge, England : 2003). PMID 32725038 DOI: 10.1039/d0dt90149k  0.146
2005 Schultz AJ, Cowan JA, Hitchman MA, Stratemeier H. Single-crystal neutron-diffraction study of 3.4% Zn-doped (ND4)2[Cu(D2O)6](SO4)2 at 20 K. Acta Crystallographica. Section C, Crystal Structure Communications. 61: m234-6. PMID 15876707 DOI: 10.1107/S0108270105009121  0.144
2021 Thompson Z, Greve J, Cowan JA. Enhanced Synergism and Mechanism of Action Studies of Synthetic Antimicrobial Metallopeptides. Chemmedchem. PMID 33825350 DOI: 10.1002/cmdc.202100063  0.14
2004 Tregenna-Piggott PL, Spichiger D, Carver G, Frey B, Meier R, Weihe H, Cowan JA, McIntyre GJ, Zahn G, Barra AL. Structure and bonding of the vanadium(III) hexa-aqua cation. 1. Experimental characterization and ligand-field analysis. Inorganic Chemistry. 43: 8049-60. PMID 15578844 DOI: 10.1021/Ic049292L  0.138
2022 Kaiyrzhanov R, Zaki MS, Lau T, Sen S, Azizimalamiri R, Zamani M, Sayin GY, Hilander T, Efthymiou S, Chelban V, Brown R, Thompson K, Scarano MI, Ganesh J, Koneev K, ... ... Cowan JA, et al. Phenotypic continuum of NFU1-related disorders. Annals of Clinical and Translational Neurology. PMID 36256512 DOI: 10.1002/acn3.51679  0.135
1999 Dudev T, Cowan JA, Lim C. Competitive binding in magnesium coordination chemistry: Water versus ligands of biological interest Journal of the American Chemical Society. 121: 7665-7673. DOI: 10.1021/ja984470t  0.132
2002 Cowan JA. Structural and catalytic chemistry of magnesium-dependent enzymes. Biometals : An International Journal On the Role of Metal Ions in Biology, Biochemistry, and Medicine. 15: 225-35. PMID 12206389 DOI: 10.1023/A:1016022730880  0.131
2004 Cowan JA, Howard JAK. Dipotassium rhodizonate Acta Crystallographica Section E: Structure Reports Online. 60: m511-m513. DOI: 10.1107/S160053680400529X  0.12
2013 Qi W, Li J, Cowan JA. Human ferredoxin-2 displays a unique conformational change. Dalton Transactions (Cambridge, England : 2003). 42: 3088-91. PMID 23208207 DOI: 10.1039/c2dt32018e  0.115
1999 Sreedhara A, Patwardhan A, Cowan JA. Novel reagents for targeted cleavage of RNA sequences: Towards a new family of inorganic pharmaceuticals Chemical Communications. 1147-1148.  0.115
2003 Lam WH, Shimada S, Batsanov AS, Lin Z, Marder TB, Cowan JA, Howard JAK, Mason SA, McIntyre GJ. Accurate molecular structures of 16-electron rhodium hydrido boryl complexes: Low-temperature single-crystal X-ray and neutron diffraction and computational studies of [(PR3)2RhHCl(boryl)] (boryl = Bpin, Bcat) Organometallics. 22: 4557-4568. DOI: 10.1021/Om030434D  0.115
1994 Tan J, Soriano A, Lui SM, Cowan JA. Functional Expression and Characterization of the Assimilatory-Type Sulfite Reductase from Desulfovibrio vulgaris (Hildenborough) Archives of Biochemistry and Biophysics. 312: 516-523. PMID 8037466 DOI: 10.1006/abbi.1994.1340  0.112
2004 Mork BV, Tilley TD, Schultz AJ, Cowan JA. Silylene hydride complexes of molybdenum with silicon-hydrogen interactions: neutron structure of (eta(5)-C(5)Me(5))(Me(2)PCH(2)CH(2)PMe(2))Mo(H)(SiEt(2)). Journal of the American Chemical Society. 126: 10428-40. PMID 15315459 DOI: 10.1021/Ja040026G  0.109
2003 Tregenna-Piggott PL, Andres HP, McIntyre GJ, Best SP, Wilson CC, Cowan JA. Aqua Ions. 2. Structural manifestations of the Jahn-Teller effect in the beta-alums. Inorganic Chemistry. 42: 1350-65. PMID 12588175 DOI: 10.1021/ic0259639  0.103
2005 Cowan JA, Howard JA, McIntyre GJ, Lo SM, Williams ID. Variable-temperature neutron diffraction studies of the short, strong hydrogen bonds in the crystal structure of pyridine-3,5-dicarboxylic acid. Acta Crystallographica. Section B, Structural Science. 61: 724-30. PMID 16306680 DOI: 10.1107/S0108768105030077  0.1
1994 Lui SM, Cowan JA. A direct spectrophotometric method for monitoring the kinetics of T-cell cytolysis Biochimie. 76: 452-454. PMID 7849112 DOI: 10.1016/0300-9084(94)90122-8  0.093
2004 Price RD, Fernández I, Gómez GR, Ortiz FL, Davidson MG, Cowan JA, Howard JAK. The first mixed-anion complex of a lithium phosphazene: Synthesis and crystal and solution structure of [(LiCH2P(Ph) 2=NPh)·(LiOC6H2-2,6-{C(CH 3)3}-4-CH3)]2 Organometallics. 23: 5934-5938. DOI: 10.1021/Om049608X  0.089
2006 Fontaine-Vive F, Johnson MR, Kearley GJ, Cowan JA, Howard JA, Parker SF. Phonon driven proton transfer in crystals with short strong hydrogen bonds. The Journal of Chemical Physics. 124: 234503. PMID 16821925 DOI: 10.1063/1.2206774  0.083
2002 Cowan JA, Clyburne JA, Davidson MG, Harris RL, Howard JA, Küpper P, Leech MA, Richards SP. On the interaction between N-heterocyclic carbenes and organic acids: structural authentication of the first N-H...C hydrogen bond and remarkably short C-H...O interactions. Angewandte Chemie (International Ed. in English). 41: 1432-4. PMID 19750789 DOI: 10.1002/1521-3773(20020415)41:8<1432::Aid-Anie1432>3.0.Co;2-M  0.08
2008 Piccoli PMB, Cowan JA, Schultz AJ, Koetzle TF, Yap GPA, Trofimenko S. Low-temperature neutron structure determinations of a series of scorpionate complexes of molybdenum containing B{single bond}H{single bond}Mo agostic bonds Journal of Molecular Structure. 890: 63-69. DOI: 10.1016/j.molstruc.2008.03.056  0.077
2007 Gokhale N, Patwardhan A, Cowan JA. Metalloaminoglycosides: Chemistry and Biological Relevance Aminoglycoside Antibiotics: From Chemical Biology to Drug Discovery. 235-254. DOI: 10.1002/9780470149676.ch8  0.074
2003 Cowan JA, Howard JA, McIntyre GJ, Lo SM, Williams ID. Variable-temperature neutron diffraction studies of the short, strong N...O hydrogen bonds in the 1:2 co-crystal of benzene-1,2,4,5-tetracarboxylic acid and 4,4'-bipyridyl. Acta Crystallographica. Section B, Structural Science. 59: 794-801. PMID 14634257 DOI: 10.1107/S0108768103024984  0.072
2021 Yu Z, Hendricks AL, Cowan JA. G-quadruplex targeting chemical nucleases as a nonperturbative tool for analysis of cellular G-quadruplex DNA. Iscience. 24: 102661. PMID 34189433 DOI: 10.1016/j.isci.2021.102661  0.071
1993 Tan J, Cowan JA. Sequence and activity of an endogenous promoter of the assimilatory sulfite reductase gene from Desulfovibrio vulgaris (Hildenborough) Biotechnology Letters. 15: 901-906. DOI: 10.1007/BF00131754  0.068
2022 Greve JM, Cowan JA. Tackling antimicrobial stewardship through synergy and antimicrobial peptides. Rsc Medicinal Chemistry. 13: 511-521. PMID 35694695 DOI: 10.1039/d2md00048b  0.066
2006 Cowan JA, Howard JA, Mason SA, McIntyre GJ, Lo SM, Mak T, Chui SS, Cai J, Cha JA, Williams ID. Neutron diffraction studies of the 1:1 and 2:1 cocrystals of benzene-1,2,4,5-tetracarboxylic acid and 4,4'-bipyridine. Acta Crystallographica. Section C, Crystal Structure Communications. 62: o157-61. PMID 16598132 DOI: 10.1107/S0108270106004008  0.061
2007 Cowan JA, Howard JAK, Puschmann H, Williams ID. Short N⋯O hydrogen bonds in the 1:1 adduct of 4,4′-bipyridyl and oxalic acid Acta Crystallographica Section E: Structure Reports Online. 63: o1240-o1242. DOI: 10.1107/S1600536807005156  0.06
1978 Toussaint A, Lefebvre N, Scott JR, Cowan JA, de Bruijn F, Bukhari AI. Relationships between temperate phages Mu and P1. Virology. 89: 146-61. PMID 685175 DOI: 10.1016/0042-6822(78)90048-X  0.059
2003 Tam CN, Cowan JA, Schultz AJ, Young VG, Trouw FR, Sykes AG. Neutron and X-ray diffraction, inelastic neutron scattering, and solid-state 13C NMR investigations of polymorphic p-chlorophenylformamide: Absence of proton transfer along the intermolecular N-H⋯O hydrogen bond Journal of Physical Chemistry B. 107: 7601-7606.  0.059
1981 Cowan JA, Scott JR. Incompatibility among group Y plasmids Plasmid. 6: 202-221. PMID 7029581 DOI: 10.1016/0147-619X(81)90067-6  0.058
2004 Belot JA, Clark J, Cowan JA, Harbison GS, Kolesnikov AI, Kye YS, Schultz AJ, Silvernail C, Zhao X. The shortest symmetrical O-H⋯O hydrogen bond has a low-barrier double-well potential Journal of Physical Chemistry B. 108: 6922-6926. DOI: 10.1021/Jp0496710  0.058
2000 Puapaiboon U, Jai-nhuknan J, Cowan JA. Study of exonuclease reactivity using MALDI-TOF mass spectrometry Proceedings of Spie - the International Society For Optical Engineering. 3924: 116-120.  0.057
2008 Cowan JA, Nave C. The optimum conditions to collect X-ray data from very small samples. Journal of Synchrotron Radiation. 15: 458-62. PMID 18728316 DOI: 10.1107/S0909049508014623  0.055
2003 Tuck D, O'Connell R, Gershkovich P, Cowan J. An approach to object-relational mapping in bioscience domains. Proceedings. Amia Symposium. 820-4. PMID 12463939  0.055
2004 Johnson KB, Ravich WJ, Cowan JA. Brainstorming about next-generation computer-based documentation: an AMIA clinical working group survey. International Journal of Medical Informatics. 73: 665-74. PMID 15325323 DOI: 10.1016/j.ijmedinf.2004.05.009  0.055
2005 Ding Y, Xu J, Prewitt CT, Hemley RJ, Mao HK, Cowan JA, Zhang J, Qian J, Vogel SC, Lokshin K, Zhao Y. Variable pressure-temperature neutron diffraction of wüstite (Fe1-x O): Absence of long-range magnetic order to 20 GPa Applied Physics Letters. 86: 1-3. DOI: 10.1063/1.1852075  0.054
2021 Jones T, Marks P, Cowan J, Kainth D, Petrie R. Cytoplasmic pressure maintains epithelial integrity and inhibits cell motility. Physical Biology. PMID 34521072 DOI: 10.1088/1478-3975/ac267a  0.052
2002 Cowan JA. An inorganic approach to drug design: Novel inorganic nucleases Indian Journal of Chemistry - Section a Inorganic, Physical, Theoretical and Analytical Chemistry. 41: 65-72.  0.048
2004 Cowan JA. Alkali and Alkaline Earth Ion Recognition and Transport Comprehensive Coordination Chemistry Ii. 8: 123-140. DOI: 10.1016/B0-08-043748-6/08197-4  0.045
1965 Cowan JA. Familial Glaucoma Jama: the Journal of the American Medical Association. 191: 526-530. PMID 14239022 DOI: 10.1001/jama.1965.03080070010003  0.043
2011 Moore DR, Cowan JA, Riley A, Edmondson-Jones AM, Ferguson MA. Development of auditory processing in 6- to 11-yr-old children. Ear and Hearing. 32: 269-85. PMID 21233712 DOI: 10.1097/AUD.0b013e318201c468  0.042
2004 Wainess RM, Dimick JB, Cowan JA, Henke PK, Stanley JC, Upchurch GR. Epidemiology of surgically treated abdominal aortic aneurysms in the United States, 1988 to 2000. Vascular. 12: 218-24. PMID 15704315 DOI: 10.1258/Rsmvasc.12.4.218  0.042
2006 Amitay S, Irwin A, Hawkey DJ, Cowan JA, Moore DR. A comparison of adaptive procedures for rapid and reliable threshold assessment and training in naive listeners. The Journal of the Acoustical Society of America. 119: 1616-25. PMID 16583906 DOI: 10.1121/1.2164988  0.042
2014 Bowton E, Field JR, Wang S, Schildcrout JS, Van Driest SL, Delaney JT, Cowan J, Weeke P, Mosley JD, Wells QS, Karnes JH, Shaffer C, Peterson JF, Denny JC, Roden DM, et al. Biobanks and electronic medical records: enabling cost-effective research. Science Translational Medicine. 6: 234cm3. PMID 24786321 DOI: 10.1126/Scitranslmed.3008604  0.04
2003 Dimick JB, Pronovost PJ, Cowan JA, Lipsett PA, Stanley JC, Upchurch GR. Variation in postoperative complication rates after high-risk surgery in the United States. Surgery. 134: 534-40; discussion 5. PMID 14605612 DOI: 10.1016/S0039-6060(03)00273-3  0.038
2011 Cowan J, Makanji H, Mudgal C, Jupiter J, Ring D. Determinants of return to work after carpal tunnel release. The Journal of Hand Surgery. 37: 18-27. PMID 22137062 DOI: 10.1016/j.jhsa.2011.10.033  0.037
2012 Ramirez AH, Shi Y, Schildcrout JS, Delaney JT, Xu H, Oetjens MT, Zuvich RL, Basford MA, Bowton E, Jiang M, Speltz P, Zink R, Cowan J, Pulley JM, Ritchie MD, et al. Predicting warfarin dosage in European-Americans and African-Americans using DNA samples linked to an electronic health record. Pharmacogenomics. 13: 407-18. PMID 22329724 DOI: 10.2217/Pgs.11.164  0.036
2007 Cowan J, Lozano-Calderón S, Ring D. Quality of prospective controlled randomized trials. Analysis of trials of treatment for lateral epicondylitis as an example. The Journal of Bone and Joint Surgery. American Volume. 89: 1693-9. PMID 17671006 DOI: 10.2106/JBJS.F.00858  0.036
2006 Cowan JA, Dimick JB, Henke PK, Rectenwald J, Stanley JC, Upchurch GR. Epidemiology of aortic aneurysm repair in the United States from 1993 to 2003. Annals of the New York Academy of Sciences. 1085: 1-10. PMID 17182917 DOI: 10.1196/Annals.1383.030  0.035
2006 Cowan JA, Dimick JB, Wainess R, Upchurch GR, Chandler WF, La Marca F. Changes in the utilization of spinal fusion in the United States. Neurosurgery. 59: 15-20; discussion 15. PMID 16823295 DOI: 10.1227/01.Neu.0000219836.54861.Cd  0.034
2003 Wainess RM, Dimick JB, Upchurch GR, Cowan JA, Mulholland MW. Epidemiology of surgically treated gastric cancer in the United States, 1988-2000. Journal of Gastrointestinal Surgery : Official Journal of the Society For Surgery of the Alimentary Tract. 7: 879-83. PMID 14592661 DOI: 10.1016/S1091-255X(03)00150-1  0.031
2005 Mukherjee D, Wainess RM, Dimick JB, Cowan JA, Rajagopalan S, Chetcuti S, Grossman PM, Upchurch GR. Variation in outcomes after percutaneous coronary intervention in the United States and predictors of periprocedural mortality. Cardiology. 103: 143-7. PMID 15722631 DOI: 10.1159/000084029  0.029
2004 Taub DA, Miller DC, Cowan JA, Dimick JB, Montie JE, Wei JT. Impact of surgical volume on mortality and length of stay after nephrectomy. Urology. 63: 862-7. PMID 15134966 DOI: 10.1016/j.urology.2003.11.037  0.029
2008 Cowan JA, McGillicuddy JE. Images in clinical medicine. Reversal of traumatic quadriplegia after closed reduction. The New England Journal of Medicine. 359: 2154. PMID 19005199 DOI: 10.1056/NEJMicm064490  0.028
2003 Dimick JB, Pronovost PJ, Cowan JA, Lipsett PA. Postoperative complication rates after hepatic resection in Maryland hospitals. Archives of Surgery (Chicago, Ill. : 1960). 138: 41-6. PMID 12511147 DOI: 10.1001/Archsurg.138.1.41  0.028
2016 Inguane CA, Gloyd S, Manuel JL, Brown C, Wong V, Augusto O, Hassan WM, Vieira L, Afonso P, Jamnadás M, Bernard JJ, Cowan J, Kalibala S, Pfeiffer J. Assessment of linkages from HIV testing to enrolment and retention in HIV care in Central Mozambique. Journal of the International Aids Society. 19: 20846. PMID 27443273 DOI: 10.7448/Ias.19.5.20846  0.028
2004 Dimick JB, Cowan JA, Colletti LM, Upchurch GR. Hospital teaching status and outcomes of complex surgical procedures in the United States. Archives of Surgery (Chicago, Ill. : 1960). 139: 137-41. PMID 14769569 DOI: 10.1001/Archsurg.139.2.137  0.027
2022 Manhiça I, Augusto O, Sherr K, Cowan J, Cuco RM, Agostinho S, Macuacua BC, Ramiro I, Carimo N, Matsinhe MB, Gloyd S, Chicumbe S, Machava R, Tembe S, Fernandes Q. COVID-19-related healthcare impacts: an uncontrolled, segmented time-series analysis of tuberculosis diagnosis services in Mozambique, 2017-2020. Bmj Global Health. 7. PMID 35443938 DOI: 10.1136/bmjgh-2021-007878  0.027
2004 Cowan JA, Barkhoudarian G, Yang LJ, Thompson BG. Progression of a posterior communicating artery infundibulum into an aneurysm in a patient with Alagille syndrome. Case report. Journal of Neurosurgery. 101: 694-6. PMID 15481729 DOI: 10.3171/jns.2004.101.4.0694  0.027
2004 Upchurch GR, Dimick JB, Wainess RM, Eliason JL, Henke PK, Cowan JA, Eagleton MJ, Srivastava SD, Stanley JC. Diffusion of new technology in health care: the case of aorto-iliac occlusive disease. Surgery. 136: 812-8. PMID 15467666 DOI: 10.1016/J.Surg.2004.06.019  0.027
2015 Cowan J, Michel C, Manhiça I, Monivo C, Saize D, Creswell J, Gloyd S, Micek M. Implementing rapid testing for tuberculosis in Mozambique. Bulletin of the World Health Organization. 93: 125-30. PMID 25883406 DOI: 10.2471/BLT.14.138560  0.027
2004 Vemuri C, Wainess RM, Dimick JB, Cowan JA, Henke PK, Stanley JC, Upchurch GR. Effect of increasing patient age on complication rates following intact abdominal aortic aneurysm repair in the United States. The Journal of Surgical Research. 118: 26-31. PMID 15093713 DOI: 10.1016/J.Jss.2004.02.007  0.026
2015 Schildcrout JS, Shi Y, Danciu I, Bowton E, Field JR, Pulley JM, Basford M, Gregg W, Cowan J, Harrell FE, Roden DM, Peterson JF, Denny JC. A prognostic model based on readily available clinical data enriched a preemptive pharmacogenetic testing program. Journal of Clinical Epidemiology. PMID 26628336 DOI: 10.1016/J.Jclinepi.2015.08.028  0.026
2004 Dimick JB, Pronovost PJ, Cowan JA, Wainess RM, Upchurch GR. Should older patients be selectively referred to high-volume centers for abdominal aortic surgery? Vascular. 12: 51-6. PMID 15127855 DOI: 10.1258/Rsmvasc.12.1.51  0.026
2003 Cowan JA, Dimick JB, Henke PK, Huber TS, Stanley JC, Upchurch GR. Surgical treatment of intact thoracoabdominal aortic aneurysms in the United States: hospital and surgeon volume-related outcomes. Journal of Vascular Surgery. 37: 1169-74. PMID 12764260 DOI: 10.1016/S0741-5214(03)00085-5  0.026
2003 Deen HG, Cowan JA, Dimick JB, Thompson BG, Stanley JC, Upchurch GR. Surgeon volume and carotid endarterectomy [4] (multiple letters) Journal of the American College of Surgeons. 196: 826-827. PMID 12742223 DOI: 10.1016/S1072-7515(03)00135-2  0.025
2003 Cowan JA, Dimick JB, Wainess RM, Upchurch GR, Thompson BG. Outcomes after cerebral aneurysm clip occlusion in the United States: the need for evidence-based hospital referral. Journal of Neurosurgery. 99: 947-52. PMID 14705719 DOI: 10.3171/Jns.2003.99.6.0947  0.025
2008 Thompson DA, Cowan J, Holzmueller C, Wu AW, Bass E, Pronovost P. Planning and implementing a systems-based patient safety curriculum in medical education. American Journal of Medical Quality. 23: 271-278. PMID 18658100 DOI: 10.1177/1062860608317763  0.025
2006 Cowan JA, Jones B, Ho H. Safety belt use by law enforcement officers on reality television: a missed opportunity for injury prevention? The Journal of Trauma. 61: 1001-4. PMID 17033579 DOI: 10.1097/01.ta.0000236642.02701.e8  0.024
2003 Dimick JB, Cowan JA, Henke PK, Wainess RM, Posner S, Stanley JC, Upchurch GR. Hospital volume-related differences in aorto-bifemoral bypass operative mortality in the United States. Journal of Vascular Surgery. 37: 970-5. PMID 12756341 DOI: 10.1067/Mva.2003.207  0.024
2005 Eliason JL, Wainess RM, Dimick JB, Cowan JA, Henke PK, Stanley JC, Upchurch GR. The effect of secondary operations on mortality following abdominal aortic aneurysm repair in the United States: 1988-2001. Vascular and Endovascular Surgery. 39: 465-72. PMID 16382267 DOI: 10.1177/153857440503900602  0.024
2019 De Schacht C, Mutaquiha C, Faria F, Castro G, Manaca N, Manhiça I, Cowan J. Barriers to access and adherence to tuberculosis services, as perceived by patients: A qualitative study in Mozambique. Plos One. 14: e0219470. PMID 31291352 DOI: 10.1371/journal.pone.0219470  0.024
2003 Dimick JB, Pronovost PJ, Cowan JA, Lipsett PA. Surgical volume and quality of care for esophageal resection: do high-volume hospitals have fewer complications? The Annals of Thoracic Surgery. 75: 337-41. PMID 12607635 DOI: 10.1016/S0003-4975(02)04409-0  0.023
2003 Block BM, Liu SS, Rowlingson AJ, Cowan AR, Cowan JA, Wu CL. Efficacy of postoperative epidural analgesia: a meta-analysis. Jama. 290: 2455-63. PMID 14612482 DOI: 10.1001/jama.290.18.2455  0.023
2018 Cowan J, Goldhaber D. Do bonuses affect teacher staffing and student achievement in high poverty schools? Evidence from an incentive for national board certified teachers in Washington State. Economics of Education Review. 65: 138-152. PMID 30116073 DOI: 10.1016/j.econedurev.2018.06.010  0.022
2009 Binswanger IA, Cowan JA. Firearms in major motion pictures, 1995-2004. The Journal of Trauma. 66: 906-11. PMID 19276772 DOI: 10.1097/TA.0b013e31816142e1  0.021
2003 Dimick JB, Cowan JA, Stanley JC, Henke PK, Pronovost PJ, Upchurch GR. Surgeon specialty and provider volumes are related to outcome of intact abdominal aortic aneurysm repair in the United States. Journal of Vascular Surgery. 38: 739-44. PMID 14560223 DOI: 10.1016/S0741-5214(03)00470-1  0.021
2003 Dimick JB, Cowan JA, Upchurch GR, Colletti LM. Hospital volume and surgical outcomes for elderly patients with colorectal cancer in the United States. The Journal of Surgical Research. 114: 50-6. PMID 13678698 DOI: 10.1016/S0022-4804(03)00207-5  0.021
2003 Dimick JB, Cowan JA, Knol JA, Upchurch GR. Hepatic resection in the United States: indications, outcomes, and hospital procedural volumes from a nationally representative database. Archives of Surgery (Chicago, Ill. : 1960). 138: 185-91. PMID 12578418 DOI: 10.1001/Archsurg.138.2.185  0.021
2003 Cowan JA, Dimick JB, Leveque JC, Thompson BG, Upchurch GR, Hoff JT. The impact of provider volume on mortality after intracranial tumor resection. Neurosurgery. 52: 48-53; discussion 53. PMID 12493100 DOI: 10.1097/00006123-200301000-00005  0.021
2003 Cowan JA, Dimick JB, Wainess RM, Henke PK, Stanley JC, Upchurch GR. Ruptured thoracoabdominal aortic aneurysm treatment in the United States: 1988 to 1998. Journal of Vascular Surgery. 38: 319-22. PMID 12891114 DOI: 10.1016/S0741-5214(03)00227-1  0.02
2004 Dimick JB, Wainess RM, Cowan JA, Upchurch GR, Knol JA, Colletti LM. National trends in the use and outcomes of hepatic resection. Journal of the American College of Surgeons. 199: 31-8. PMID 15217626 DOI: 10.1016/J.Jamcollsurg.2004.03.005  0.02
2010 Park P, Foley KT, Cowan JA, Marca FL. Minimally invasive pedicle screw fixation utilizing O-arm fluoroscopy with computer-assisted navigation: Feasibility, technique, and preliminary results. Surgical Neurology International. 1: 44. PMID 20975974 DOI: 10.4103/2152-7806.68705  0.02
2004 Knipp BS, Dimick JB, Eliason JL, Cowan JA, Henke PK, Proctor MS, Stanley JC, Upchurch GR. Diffusion of new technology for the treatment of renovascular hypertension in the United States: surgical revascularization versus catheter-based therapy, 1988-2001. Journal of Vascular Surgery. 40: 717-23. PMID 15472600 DOI: 10.1016/J.Jvs.2004.07.029  0.019
2002 Dimick JB, Pronovost PJ, Cowan JA, Ailawadi G, Upchurch GR. The volume-outcome effect for abdominal aortic surgery: differences in case-mix or complications? Archives of Surgery (Chicago, Ill. : 1960). 137: 828-32. PMID 12093341 DOI: 10.1001/Archsurg.137.7.828  0.019
2004 Cowan JA, Wainess R, Dimick JB, Upchurch GR, Thompson BG. Council of State Neurosurgical Societies Resident Award: The utilization of carotid endarterectomy by neurosurgeons in the United States from 1990 to 2000. Clinical Neurosurgery. 51: 329-31. PMID 15571162  0.019
2012 Cowan JA, Kohler TA, Johnson CD, Cooper K, Bocinsky RK. Supply, demand, return rates, and resource depression Emergence and Collapse of Early Villages: Models of Central Mesa Verde Archaeology. 129-144.  0.018
2004 Huffman MH, Cowan JA. Redefine care delivery and documentation. Nursing Management. 35: 34-8. PMID 14767231  0.018
2003 Dimick JB, Pronovost PJ, Cowan JA, Lipsett PA. Complications and costs after high-risk surgery: where should we focus quality improvement initiatives? Journal of the American College of Surgeons. 196: 671-8. PMID 12742194 DOI: 10.1016/S1072-7515(03)00122-4  0.017
2003 Eliason JL, Wainess RM, Proctor MC, Dimick JB, Cowan JA, Upchurch GR, Stanley JC, Henke PK. A national and single institutional experience in the contemporary treatment of acute lower extremity ischemia. Annals of Surgery. 238: 382-9; discussion 38. PMID 14501504 DOI: 10.1097/01.Sla.0000086663.49670.D1  0.017
2003 Boxer LK, Dimick JB, Wainess RM, Cowan JA, Henke PK, Stanley JC, Upchurch GR. Payer status is related to differences in access and outcomes of abdominal aortic aneurysm repair in the United States. Surgery. 134: 142-5. PMID 12947310 DOI: 10.1067/Msy.2003.214  0.017
2004 Park P, Chandler WF, Barkan AL, Orrego JJ, Cowan JA, Griffith KA, Tsien C. The role of radiation therapy after surgical resection of nonfunctional pituitary macroadenomas. Neurosurgery. 55: 100-6; discussion 10. PMID 15214978  0.017
2008 Vranceanu AM, Safren S, Zhao M, Cowan J, Ring D. Disability and psychologic distress in patients with nonspecific and specific arm pain. Clinical Orthopaedics and Related Research. 466: 2820-6. PMID 18636306 DOI: 10.1007/s11999-008-0378-1  0.017
2003 Ziai WC, Port JD, Cowan JA, Garonzik IM, Bhardwaj A, Rigamonti D. Decompressive craniectomy for intractable cerebral edema: experience of a single center. Journal of Neurosurgical Anesthesiology. 15: 25-32. PMID 12499979 DOI: 10.1097/00008506-200301000-00005  0.016
2007 Cowan JA, Chandler WF. Changing trends in the use and costs of procedures performed by neurosurgeons in the United States. Clinical Neurosurgery. 54: 209-11. PMID 18504921  0.016
2009 Hanauer DA, Englesbe MJ, Cowan JA, Campbell DA. Informatics and the American College of Surgeons National Surgical Quality Improvement Program: automated processes could replace manual record review. Journal of the American College of Surgeons. 208: 37-41. PMID 19228500 DOI: 10.1016/j.jamcollsurg.2008.08.030  0.016
2012 Cowan JA, Devine CM. Process evaluation of an environmental and educational nutrition intervention in residential drug-treatment facilities. Public Health Nutrition. 15: 1159-67. PMID 22475412 DOI: 10.1017/S1368980012000572  0.015
2005 Cowan JA, McGirt MJ, Woodworth G, Rigamonti D, Williams MA. The syndrome of hydrocephalus in young and middle-aged adults (SHYMA). Neurological Research. 27: 540-7. PMID 15978182 DOI: 10.1179/016164105X17242  0.014
2005 McGirt MJ, Cowan JA, Gala V, Garton HJ, Muraszko KM, Thompson BG. Surgical reversal of prolonged blindness from a metastatic neuroblastoma. Child's Nervous System : Chns : Official Journal of the International Society For Pediatric Neurosurgery. 21: 583-6. PMID 16028089 DOI: 10.1007/s00381-004-1062-8  0.014
2002 Cowan JA, Dimick JB, Thompson BG, Stanley JC, Upchurch GR. Surgeon volume as an indicator of outcomes after carotid endarterectomy: an effect independent of specialty practice and hospital volume. Journal of the American College of Surgeons. 195: 814-21. PMID 12495314 DOI: 10.1016/S1072-7515(02)01345-5  0.014
2003 Dimick JB, Cowan JA, Ailawadi G, Wainess RM, Upchurch GR. National variation in operative mortality rates for esophageal resection and the need for quality improvement. Archives of Surgery (Chicago, Ill. : 1960). 138: 1305-9. PMID 14662529 DOI: 10.1001/Archsurg.138.12.1305  0.013
2010 El-Sayed AM, Hadley C, Tessema F, Tegegn A, Cowan JA, Galea S. Household food insecurity and symptoms of neurologic disorder in Ethiopia: an observational analysis. Bmc Public Health. 10: 802. PMID 21194486 DOI: 10.1186/1471-2458-10-802  0.013
2010 Vranceanu AM, Safren SA, Cowan J, Ring DC. Health concerns and somatic symptoms explain perceived disability and idiopathic hand and arm pain in an orthopedics surgical practice: a path-analysis model. Psychosomatics. 51: 330-7. PMID 20587761 DOI: 10.1176/appi.psy.51.4.330  0.013
2012 Cowan JA, Bocinsky RK, Kohler TA, Johnson CD. How hunting changes the VEP world, and how the VEP world changes hunting Emergence and Collapse of Early Villages: Models of Central Mesa Verde Archaeology. 145-152.  0.012
2020 Voss J, Dacey D, Ruiz S, Burkhardt A, Pujolar A, Swope C, Lehman M, Shaw T, Leon J, Erich R, Cowan J, West C, Walters C, Macias E, Lucas P. Public Health Response to Zika Virus Exposure of Air Force Members Deployed to Caribbean Islands, 2016. Military Medicine. PMID 32875318 DOI: 10.1093/Milmed/Usaa188  0.012
2009 Cowan JA, Dubosh N, Hadley C. Seatbelt and helmet depiction on the big screen blockbuster injury prevention messages? The Journal of Trauma. 66: 912-7. PMID 19276773 DOI: 10.1097/Ta.0B013E318166D740  0.011
2008 Hadley C, Tegegn A, Tessema F, Cowan JA, Asefa M, Galea S. Food insecurity, stressful life events and symptoms of anxiety and depression in east Africa: evidence from the Gilgel Gibe growth and development study. Journal of Epidemiology and Community Health. 62: 980-6. PMID 18854502 DOI: 10.1136/Jech.2007.068460  0.011
2005 Jones GL, Baker J, Chen WC, Collett B, Cowan JA, Dias MF, Gentile TR, Hoffmann C, Koetzle T, Lee WT, Littrell K, Miller M, Schultz A, Snow WM, Tong X, et al. Continuously operating compact 3He-based neutron spin filter Physica B: Condensed Matter. 356: 86-90. DOI: 10.1016/j.physb.2004.10.054  0.01
2014 Cowan JA. Calcium Rsc Metallobiology. 2014: 123-152.  0.01
2013 Suarez CJ, Glover WA, Cowan J, Smith A, Clarridge JE. Mycotic aneurysm of the abdominal aorta caused by Haemophilus influenzae type f. Journal of Medical Microbiology. 62: 658-60. PMID 23355310 DOI: 10.1099/jmm.0.055228-0  0.01
2013 Cowan JA, Devine CM. Diet and body composition outcomes of an environmental and educational intervention among men in treatment for substance addiction. Journal of Nutrition Education and Behavior. 45: 154-8. PMID 22633178 DOI: 10.1016/J.Jneb.2011.10.011  0.01
2010 El-Sayed AM, Hadley C, Tessema F, Tegegn A, Cowan JA, Galea S. Back and neck pain and psychopathology in rural sub-Saharan Africa: evidence from the Gilgel Gibe Growth and Development Study, Ethiopia. Spine. 35: 684-9. PMID 20139812 DOI: 10.1097/Brs.0B013E3181B4926E  0.01
2008 Vranceanu AM, Safren S, Cowan J, Ring D. The development of the negative pain thoughts questionnaire. Pain Practice : the Official Journal of World Institute of Pain. 8: 337-41. PMID 18503620 DOI: 10.1111/j.1533-2500.2008.00213.x  0.01
2008 Cowan JA. Epidemiology of Anthrax in North Dakota. American Journal of Public Health and the Nation's Health. 30: 411-6. PMID 18015208 DOI: 10.2105/AJPH.30.4.411  0.01
2007 Cowan JA, Ziewacz J, Dimick JB, Upchurch GR, Thompson BG. Use of endovascular coil embolization and surgical clip occlusion for cerebral artery aneurysms. Journal of Neurosurgery. 107: 530-5. PMID 17886551 DOI: 10.3171/Jns-07/09/0530  0.01
2007 Cowan J, Lozano-Calder-n S, Ring D. Quality of Prospective Controlled Randomized Trials The Journal of Bone and Joint Surgery-American Volume. 89: 1693-1699. DOI: 10.2106/00004623-200708000-00004  0.01
2005 Cowan JA. Airborne law enforcement - Fighting crime from the air Journal of Navigation. 58: 165-179. DOI: 10.1017/S0373463305003243  0.01
2003 Dimick JB, Cowan JA, Chen SL. Emerging approaches for assessing and improving the quality of surgical care. Current Surgery. 60: 241-6. PMID 15212057  0.01
2003 Cowan JA, Brahma B, Sagher O. Surgical treatment of trigeminal neuralgia: Comparison of microvascular decompression, percutaneous ablation, and stereotactic radiosurgery Techniques in Neurosurgery. 8: 157-167. DOI: 10.1097/00127927-200308030-00004  0.01
1988 Cowan JA. The ’Older’ Doctor Jama: the Journal of the American Medical Association. 260: 3494. DOI: 10.1001/jama.1988.03410230112041  0.01
1944 WITTKOWER ED, COWAN J. Some Psychological Aspects of Sexual Promiscuity Psychosomatic Medicine. 6: 287-294. DOI: 10.1097/00006842-194410000-00002  0.01
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