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Gabriella Gobbi, MD PhD - Related publications

Psychiatry McGill University, Montreal, QC, Canada 
Mental Illness and Addiction, Neurosciences
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50 most relevant papers in past 60 days:
Year Citation  Score
2021 Yang Y, Zhang L, Yu J, Ma Z, Li M, Wang J, Hu P, Zou J, Liu X, Liu Y, An S, Xiang C, Guo X, Hao Q, Xu TR. A Novel 5-HT Receptor Agonist of Herbal Compounds and One of the Therapeutic Uses for Alzheimer's Disease. Frontiers in Pharmacology. 12: 735876. PMID 34552493 DOI: 10.3389/fphar.2021.735876   
2021 Guo G, Tang J, Shi M, Yang C, Ou H, Chen W. MK212, a 5-hydroxytryptamine 2C receptor agonist, reverses prepulse inhibition deficits in the medial prefrontal cortex and ventral hippocampus. Progress in Neuro-Psychopharmacology & Biological Psychiatry. 110441. PMID 34560172 DOI: 10.1016/j.pnpbp.2021.110441   
2021 Wang X, Zhou H, Wang X, Lei K, Wang S. Design, Synthesis, and In Vivo and In Silico Evaluation of Coumarin Derivatives with Potential Antidepressant Effects. Molecules (Basel, Switzerland). 26. PMID 34577028 DOI: 10.3390/molecules26185556   
2021 da Silva Moreira LK, Silva RR, da Silva DM, Mendes MAS, de Brito AF, de Carvalho FS, Sanz G, Rodrigues MF, da Silva ACG, Thomaz DV, de Oliveira V, Vaz BG, Lião LM, Valadares MC, de Souza Gil E, et al. Anxiolytic- and antidepressant-like effects of new phenylpiperazine derivative LQFM005 and its hydroxylated metabolite in mice. Behavioural Brain Research. 113582. PMID 34536431 DOI: 10.1016/j.bbr.2021.113582   
2021 Borroto-Escuela DO, Ambrogini P, Narvaez M, Di Liberto V, Beggiato S, Ferraro L, Fores-Pons R, Alvarez-Contino JE, Lopez-Salas A, Mudò G, Díaz-Cabiale Z, Fuxe K. Serotonin Heteroreceptor Complexes and Their Integration of Signals in Neurons and Astroglia-Relevance for Mental Diseases. Cells. 10. PMID 34440670 DOI: 10.3390/cells10081902   
2021 de Cates AN, Wright LC, Martens MAG, Gibson D, Türkmen C, Filippini N, Cowen PJ, Harmer CJ, Murphy SE. Déjà-vu? Neural and behavioural effects of the 5-HT receptor agonist, prucalopride, in a hippocampal-dependent memory task. Translational Psychiatry. 11: 497. PMID 34602607 DOI: 10.1038/s41398-021-01568-4   
2021 Vila-Pueyo M, Page K, Murdock PR, Loraine HJ, Woodrooffe AJ, Johnson KW, Goadsby PJ, Holland PR. The selective 5-HT receptor agonist lasmiditan inhibits trigeminal nociceptive processing: implications for migraine and cluster headache. British Journal of Pharmacology. PMID 34600443 DOI: 10.1111/bph.15699   
2021 Yuan XC, Yan XJ, Tian LX, Guo YX, Zhao YL, Baba SS, Wang YY, Liang LL, Jia H, Xu LP, Li L, Lin H, Huo FQ. 5-HT Receptor Is Involved in Electroacupuncture Inhibition of Chronic Pain in the Spinal Cord. Frontiers in Neuroscience. 15: 733779. PMID 34602973 DOI: 10.3389/fnins.2021.733779   
2021 Ye Q, Zhang X. Serotonin activates paraventricular thalamic neurons through direct depolarization and indirect disinhibition from Zona Incerta. The Journal of Physiology. PMID 34510418 DOI: 10.1113/JP282088   
2021 Jin C, Yi C, Zhong W, Xue Y, Chen K, Deng K, Wang Z, Wang T. Design, synthesis and biological evaluation of pyridinylmethylenepiperidine derivatives as potent 5-HT receptor agonists for migraine therapy. European Journal of Medicinal Chemistry. 225: 113782. PMID 34419891 DOI: 10.1016/j.ejmech.2021.113782   
2021 Zajdel P, Grychowska K, Mogilski S, Kurczab R, Satała G, Bugno R, Kos T, Gołębiowska J, Malikowska-Racia N, Nikiforuk A, Chaumont-Dubel S, Bantreil X, Pawłowski M, Martinez J, Subra G, et al. Structure-Based Design and Optimization of FPPQ, a Dual-Acting 5-HT and 5-HT Receptor Antagonist with Antipsychotic and Procognitive Properties. Journal of Medicinal Chemistry. PMID 34467765 DOI: 10.1021/acs.jmedchem.1c00224   
2021 Islam MZ, Kojima S, Sameshima M, Obi T, Yamazaki-Himeno E, Shiraishi M, Miyamoto A. Vasomotor effects of noradrenaline, 5-hydroxytryptamine, angiotensin II, bradykinin, histamine, and acetylcholine on the bat (Rhinolophus ferrumequinum) basilar artery. Comparative Biochemistry and Physiology. Toxicology & Pharmacology : Cbp. 109190. PMID 34536573 DOI: 10.1016/j.cbpc.2021.109190   
2021 Xie KY, Chien SJ, Tan BC, Chen YW. RNA editing of 5-HT R impairs insulin secretion of pancreatic beta cells via altered store-operated calcium entry. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 35: e21929. PMID 34553421 DOI: 10.1096/fj.202100265RR   
2021 Haq S, Grondin JA, Khan WI. Tryptophan-derived serotonin-kynurenine balance in immune activation and intestinal inflammation. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 35: e21888. PMID 34473368 DOI: 10.1096/fj.202100702R   
2021 Koopman N, Katsavelis D, Hove AST, Brul S, Jonge WJ, Seppen J. The Multifaceted Role of Serotonin in Intestinal Homeostasis. International Journal of Molecular Sciences. 22. PMID 34502396 DOI: 10.3390/ijms22179487   
2021 Tarbit E, Singh I, Peart JN, Bivol S, Rose'Meyer RB. Increased release of serotonin from rat primary isolated adult cardiac myofibroblasts. Scientific Reports. 11: 20376. PMID 34645867 DOI: 10.1038/s41598-021-99632-y   
2021 Jin J, Xu F, Zhang Y, Guan J, Liang X, Zhang Y, Yuan A, Liu R, Fu J. Renal ischemia/reperfusion injury in rats is probably due to the activation of the 5-HT degradation system in proximal renal tubular epithelial cells. Life Sciences. 120002. PMID 34599937 DOI: 10.1016/j.lfs.2021.120002   
2021 Lawlor RT, Mafficini A, Sciammarella C, Cantù C, Rusev BC, Piredda ML, Antonello D, Grimaldi S, Bonizzato G, Sperandio N, Marchegiani G, Malleo G, Pea A, Salvia R, Mombello A, et al. Genomic characterization of hepatoid tumors: context matters. Human Pathology. PMID 34562502 DOI: 10.1016/j.humpath.2021.09.006   
2021 Bhat SK, Ganesh CB. Serotonin (5-hydroxytryptamine)-immunoreactive neurons in the brain of the viviparous fish Gambusia affinis. Journal of Chemical Neuroanatomy. 118: 102033. PMID 34563637 DOI: 10.1016/j.jchemneu.2021.102033   
2021 Murillo-Rodríguez E, Arankowsky-Sandoval G, Budde H, Imperatori C, Machado S, Yamamoto T, Yadollahpour A, Torterolo P. In vivo brain levels of acetylcholine and 5-hydroxytryptamine after oleoylethanolamide or palmitoylethanolamide administrations are mediated by PPARα engagement. The European Journal of Neuroscience. PMID 34396611 DOI: 10.1111/ejn.15409   
2021 Avram S, Stan MS, Udrea AM, Buiu C, Boboc AA, Mernea M. 3D-ALMOND-QSAR Models to Predict the Antidepressant Effect of Some Natural Compounds. Pharmaceutics. 13. PMID 34575524 DOI: 10.3390/pharmaceutics13091449   
2021 Huang Q, Di L, Yu F, Feng X, Liu Z, Wei M, Luo Y, Xia J. Alterations in the gut microbiome with hemorrhagic transformation in experimental stroke. Cns Neuroscience & Therapeutics. PMID 34591349 DOI: 10.1111/cns.13736   
2021 Xu Q, Miao Y, Ren J, Sun Y, Li C, Cai X, Wang Z. Silencing of Nesprin-2 inhibits the differentiation of myofibroblasts from fibroblasts induced by mechanical stretch. International Wound Journal. PMID 34558192 DOI: 10.1111/iwj.13694   
2021 Leger RF, Unterwald EM. Assessing the effects of methodological differences on outcomes in the use of psychedelics in the treatment of anxiety and depressive disorders: A systematic review and meta-analysis. Journal of Psychopharmacology (Oxford, England). 2698811211044688. PMID 34519567 DOI: 10.1177/02698811211044688   
2021 Grifka-Walk HM, Jenkins BR, Kominsky DJ. Amino Acid Trp: The Far Out Impacts of Host and Commensal Tryptophan Metabolism. Frontiers in Immunology. 12: 653208. PMID 34149693 DOI: 10.3389/fimmu.2021.653208   
2021 Melhem NM, Zhong Y, Miller JM, Zanderigo F, Ogden RT, Sublette ME, Newell M, Burke A, Keilp JG, Lesanpezeshki M, Bartlett E, Brent DA, Mann JJ. Brain 5-HT1A Receptor PET Binding, Cortisol Responses to Stress, and the Familial Transmission of Suicidal Behavior. The International Journal of Neuropsychopharmacology. PMID 34555145 DOI: 10.1093/ijnp/pyab060   
2021 Li L, Lu JJ, Wang WT, Wang N, Wang LX, Ma YM, Liu S. [Potential targets of Euodiae Fructus in treatment of insomnia based on network pharmacology]. Zhongguo Zhong Yao Za Zhi = Zhongguo Zhongyao Zazhi = China Journal of Chinese Materia Medica. 46: 3016-3023. PMID 34467691 DOI: 10.19540/j.cnki.cjcmm.20210419.401   
2021 Tang HX, Lin J, Xu CB, Chen G, Liao YJ, Lei NR, Li J. Minimally modified low-density lipoprotein upregulates mouse mesenteric arterial 5-HT receptor in vivo via activation of the JAK2/STAT3 pathway. Microvascular Research. 104260. PMID 34624308 DOI: 10.1016/j.mvr.2021.104260   
2021 Nuara SG, Gourdon JC, Maddaford S, Huot P. Additive effects of mGluR positive allosteric modulation, mGluR orthosteric stimulation and 5-HTR antagonism on dyskinesia and psychosis-like behaviours in the MPTP-lesioned marmoset. Naunyn-Schmiedeberg's Archives of Pharmacology. PMID 34550406 DOI: 10.1007/s00210-021-02162-7   
2021 Yang L, Wang X, He S, Luo Y, Chen S, Shan Y, Wang R, Ding S. Heat shock treatment maintains the quality attributes of postharvest jujube fruits and delays their senescence process during cold storage. Journal of Food Biochemistry. e13937. PMID 34532870 DOI: 10.1111/jfbc.13937   
2021 Hossain R, Al-Khafaji K, Khan RA, Sarkar C, Islam MS, Dey D, Jain D, Faria F, Akbor R, Atolani O, Oliveira SMR, Siyadatpanah A, Pereira ML, Islam MT. Quercetin and/or Ascorbic Acid Modulatory Effect on Phenobarbital-Induced Sleeping Mice Possibly through GABA and GABA Receptor Interaction Pathway. Pharmaceuticals (Basel, Switzerland). 14. PMID 34451819 DOI: 10.3390/ph14080721   
2021 Jha P, Chaturvedi S, Bhat R, Jain N, Mishra AK. Insights of ligand binding in modeled h5-HT receptor: homology modeling, docking, MM-GBSA, screening and molecular dynamics. Journal of Biomolecular Structure & Dynamics. 1-13. PMID 34387135 DOI: 10.1080/07391102.2021.1961865   
2021 Zhong Z, Zhong T, Peng Y, Zhou X, Wang Z, Tang H, Wang J. Symbiont-regulated serotonin biosynthesis modulates tick feeding activity. Cell Host & Microbe. PMID 34525331 DOI: 10.1016/j.chom.2021.08.011   
2021 Kwag R, Lee J, Kim D, Lee H, Yeom M, Woo J, Cho Y, Kim HJ, Kim J, Keum G, Jeon B, Choo H. Discovery of G Protein-Biased Antagonists against 5-HTR. Journal of Medicinal Chemistry. PMID 34519505 DOI: 10.1021/acs.jmedchem.1c01093   
2021 Gerak LR, France CP. Effects of buprenorphine/lorcaserin mixtures on preference for heroin, cocaine, or saline over food using a concurrent choice procedure in rhesus monkeys. Drug and Alcohol Dependence. 227: 108991. PMID 34482043 DOI: 10.1016/j.drugalcdep.2021.108991   
2021 Wellenberg A, Brinkmann V, Bornhorst J, Ventura N, Honnen S, Fritz G. Cisplatin-induced neurotoxicity involves the disruption of serotonergic neurotransmission. Pharmacological Research. 105921. PMID 34601079 DOI: 10.1016/j.phrs.2021.105921   
2021 Moehle MS, Bender AM, Dickerson JW, Foster DJ, Qi A, Cho HP, Donsante Y, Peng W, Bryant Z, Stillwell KJ, Bridges TM, Chang S, Watson KJ, O'Neill JC, Engers JL, et al. Discovery of the First Selective M Muscarinic Acetylcholine Receptor Antagonists with Antiparkinsonian and Antidystonic Efficacy. Acs Pharmacology & Translational Science. 4: 1306-1321. PMID 34423268 DOI: 10.1021/acsptsci.0c00162   
2021 Powell WS. Eicosanoid receptors as therapeutic targets for asthma. Clinical Science (London, England : 1979). 135: 1945-1980. PMID 34401905 DOI: 10.1042/CS20190657   
2021 Nakashima F, Suzuki T, Gordon ON, Golding D, Okuno T, Giménez-Bastida JA, Yokomizo T, Schneider C. Biosynthetic Crossover of 5-Lipoxygenase and Cyclooxygenase-2 Yields 5-Hydroxy-PGE and 5-Hydroxy-PGD. Jacs Au. 1: 1380-1388. PMID 34604848 DOI: 10.1021/jacsau.1c00177   
2021 Brockett AT, Deng C, Shuster M, Perera S, DiMaggio D, Cheng M, Murkli S, Briken V, Roesch MR, Isaacs L. In Vitro and In Vivo Sequestration of Methamphetamine by a Sulfated Acyclic CB[n]-Type Receptor. Chemistry (Weinheim An Der Bergstrasse, Germany). PMID 34613641 DOI: 10.1002/chem.202102919   
2021 Shih TL, Lin KH, Chen RJ, Chen TY, Kao WT, Liu JW, Wang HH, Peng HY, Sun YY, Lu WJ. A novel naphthalimide derivative reduces platelet activation and thrombus formation via suppressing GPVI. Journal of Cellular and Molecular Medicine. PMID 34448532 DOI: 10.1111/jcmm.16886   
2021 Nobrega JN, Raymond R, Rajji TK, Pollock BG. A calcium fluorescence assay for quantification of cholinergic receptor activity of clinical drugs in serum - comparison with radioactive methods. Journal of Pharmacological and Toxicological Methods. 107118. PMID 34481920 DOI: 10.1016/j.vascn.2021.107118   
2021 Lee JC, Janda KD. Immunopharmacotherapeutic advancements in addressing methamphetamine abuse. Rsc Chemical Biology. 2: 77-93. PMID 34458776 DOI: 10.1039/d0cb00165a   
2021 Shah A, Shah AA, Nandakumar K, Kumar A, Pai A, Lobo R. In-silico and in-vivo evaluation of sesamol and its derivatives for benign prostatic hypertrophy. 3 Biotech. 11: 411. PMID 34466348 DOI: 10.1007/s13205-021-02952-z   
2021 Shan L, Martens GJM, Swaab DF. Histamine-4 Receptor: Emerging Target for the Treatment of Neurological Diseases. Current Topics in Behavioral Neurosciences. PMID 34432256 DOI: 10.1007/7854_2021_237   
2021 Van J, Frias JP, Bonora E, Raha S, Meyer J, Jung H, Cox D, Konig M, Peleshok J, Bethel MA. Gastrointestinal Tolerability of Once-Weekly Dulaglutide 3.0 mg and 4.5 mg: A Post Hoc Analysis of the Incidence and Prevalence of Nausea, Vomiting, and Diarrhea in AWARD-11. Diabetes Therapy : Research, Treatment and Education of Diabetes and Related Disorders. PMID 34514554 DOI: 10.1007/s13300-021-01140-9   
2021 Han J, Andreu V, Langreck C, Pekarskaya EA, Grinnell SG, Allain F, Magalong V, Pintar J, Kieffer BL, Harris AZ, Javitch JA, Hen R, Nautiyal KM. Mu opioid receptors on hippocampal GABAergic interneurons are critical for the antidepressant effects of tianeptine. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 34593976 DOI: 10.1038/s41386-021-01192-2   
2021 Subramanian S, Ravichandran M. Orexin receptors: Targets and applications. Fundamental & Clinical Pharmacology. PMID 34464995 DOI: 10.1111/fcp.12723   
2021 Avoli M, Lévesque M. Gabab Receptors: Are They Missing In Action In Focal Epilepsy Research? Current Neuropharmacology. PMID 34429053 DOI: 10.2174/1570159X19666210823102332   
2021 Krautmann M, Walters R, Cole P, Tena J, Bergeron LM, Messamore J, Mwangi D, Rai S, Dominowski P, Saad K, Zhu Y, Guillot M, Chouinard L. Laboratory safety evaluation of bedinvetmab, a canine anti-nerve growth factor monoclonal antibody, in dogs. Veterinary Journal (London, England : 1997). 276: 105733. PMID 34391918 DOI: 10.1016/j.tvjl.2021.105733