Shao-Cong Sun, Ph.D. - Publications

Affiliations: 
Immunology MD Anderson Cancer Center, Houston, TX, United States 
Area:
NFkB, NK cells, T-cells, Immunology, HTLV-1, autoimmunity

126 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2015 Zou Q, Jin J, Xiao Y, Zhou X, Hu H, Cheng X, Kazimi N, Ullrich SE, Sun SC. T Cell Intrinsic USP15 Deficiency Promotes Excessive IFN-γ Production and an Immunosuppressive Tumor Microenvironment in MCA-Induced Fibrosarcoma. Cell Reports. PMID 26686633 DOI: 10.1016/j.celrep.2015.11.046  1
2015 Zhang H, Sun SC. NF-κB in inflammation and renal diseases. Cell & Bioscience. 5: 63. PMID 26579219 DOI: 10.1186/s13578-015-0056-4  1
2015 Xiao Y, Sun SC. TPL2 mediates IL-17R signaling in neuroinflammation. Oncotarget. PMID 26318043  1
2015 Shi JH, Sun SC. TCR signaling to NF-κB and mTORC1: Expanding roles of the CARMA1 complex. Molecular Immunology. PMID 26260210 DOI: 10.1016/j.molimm.2015.07.024  1
2015 Zhao Y, Zhang Y, Song1 HB, Wu1 F, Wang XL, Sun SC, Cui TX, Tang DQ. Proteomic analysis revealed the altered kidney protein profile of a Cyld knockout mouse model. Genetics and Molecular Research : Gmr. 14: 5970-5978. PMID 26125796 DOI: 10.4238/2015.June.1.14  1
2015 Yang XD, Sun SC. Targeting signaling factors for degradation, an emerging mechanism for TRAF functions. Immunological Reviews. 266: 56-71. PMID 26085207 DOI: 10.1111/imr.12311  1
2015 Chang JH, Hu H, Sun SC. Survival and maintenance of regulatory T cells require the kinase TAK1. Cellular & Molecular Immunology. PMID 25891214 DOI: 10.1038/cmi.2015.27  1
2015 Ren T, Takahashi Y, Liu X, Loughran TP, Sun SC, Wang HG, Cheng H. HTLV-1 Tax deregulates autophagy by recruiting autophagic molecules into lipid raft microdomains. Oncogene. 34: 334-45. PMID 24362528 DOI: 10.1038/onc.2013.552  1
2015 Xiao Y, Jin J, Zou Q, Hu H, Cheng X, Sun SC. Peli1 negatively regulates type I interferon induction and antiviral immunity in the CNS Cell and Bioscience. 5. DOI: 10.1186/s13578-015-0024-z  1
2014 Zhang H, Hu H, Greeley N, Jin J, Matthews AJ, Ohashi E, Caetano MS, Li HS, Wu X, Mandal PK, McMurray JS, Moghaddam SJ, Sun SC, Watowich SS. STAT3 restrains RANK- and TLR4-mediated signalling by suppressing expression of the E2 ubiquitin-conjugating enzyme Ubc13. Nature Communications. 5: 5798. PMID 25503582 DOI: 10.1038/ncomms6798  1
2014 Yang Y, Ran J, Liu M, Li D, Li Y, Shi X, Meng D, Pan J, Ou G, Aneja R, Sun SC, Zhou J. CYLD mediates ciliogenesis in multiple organs by deubiquitinating Cep70 and inactivating HDAC6. Cell Research. 24: 1342-53. PMID 25342559 DOI: 10.1038/cr.2014.136  1
2014 Xiao Y, Jin J, Chang M, Nakaya M, Hu H, Zou Q, Zhou X, Brittain GC, Cheng X, Sun SC. TPL2 mediates autoimmune inflammation through activation of the TAK1 axis of IL-17 signaling. The Journal of Experimental Medicine. 211: 1689-702. PMID 24980047 DOI: 10.1084/jem.20132640  1
2014 Yu J, Zhou X, Nakaya M, Jin W, Cheng X, Sun SC. T cell-intrinsic function of the noncanonical NF-κB pathway in the regulation of GM-CSF expression and experimental autoimmune encephalomyelitis pathogenesis. Journal of Immunology (Baltimore, Md. : 1950). 193: 422-30. PMID 24899500 DOI: 10.4049/jimmunol.1303237  1
2014 Nakaya M, Xiao Y, Zhou X, Chang JH, Chang M, Cheng X, Blonska M, Lin X, Sun SC. Inflammatory T cell responses rely on amino acid transporter ASCT2 facilitation of glutamine uptake and mTORC1 kinase activation. Immunity. 40: 692-705. PMID 24792914 DOI: 10.1016/j.immuni.2014.04.007  1
2014 Zou Q, Jin J, Hu H, Li HS, Romano S, Xiao Y, Nakaya M, Zhou X, Cheng X, Yang P, Lozano G, Zhu C, Watowich SS, Ullrich SE, Sun SC. USP15 stabilizes MDM2 to mediate cancer-cell survival and inhibit antitumor T cell responses. Nature Immunology. 15: 562-70. PMID 24777531 DOI: 10.1038/ni.2885  1
2014 Jin J, Hu H, Li HS, Yu J, Xiao Y, Brittain GC, Zou Q, Cheng X, Mallette FA, Watowich SS, Sun SC. Noncanonical NF-κB pathway controls the production of type I interferons in antiviral innate immunity. Immunity. 40: 342-54. PMID 24656046 DOI: 10.1016/j.immuni.2014.02.006  1
2014 Chang JH, Hu H, Jin J, Puebla-Osorio N, Xiao Y, Gilbert BE, Brink R, Ullrich SE, Sun SC. TRAF3 regulates the effector function of regulatory T cells and humoral immune responses. The Journal of Experimental Medicine. 211: 137-51. PMID 24378539 DOI: 10.1084/jem.20131019  1
2014 Wu CF, Liu S, Lee YC, Wang R, Sun S, Yin F, Bornmann WG, Yu-Lee LY, Gallick GE, Zhang W, Lin SH, Kuang J. RSK promotes G2/M transition through activating phosphorylation of Cdc25A and Cdc25B. Oncogene. 33: 2385-94. PMID 23708659 DOI: 10.1038/onc.2013.182  1
2013 Blonska M, Joo D, Nurieva RI, Zhao X, Chiao P, Sun SC, Dong C, Lin X. Activation of the transcription factor c-Maf in T cells is dependent on the CARMA1-IKKβ signaling cascade. Science Signaling. 6: ra110. PMID 24345681 DOI: 10.1126/scisignal.2004273  1
2013 Zhong B, Liu X, Wang X, Liu X, Li H, Darnay BG, Lin X, Sun SC, Dong C. Ubiquitin-specific protease 25 regulates TLR4-dependent innate immune responses through deubiquitination of the adaptor protein TRAF3. Science Signaling. 6: ra35. PMID 23674823 DOI: 10.1126/scisignal.2003708  1
2013 Xiao Y, Jin J, Chang M, Chang JH, Hu H, Zhou X, Brittain GC, Stansberg C, Torkildsen Ø, Wang X, Brink R, Cheng X, Sun SC. Peli1 promotes microglia-mediated CNS inflammation by regulating Traf3 degradation. Nature Medicine. 19: 595-602. PMID 23603814 DOI: 10.1038/nm.3111  1
2013 Sun SC, Chang JH, Jin J. Regulation of nuclear factor-κB in autoimmunity. Trends in Immunology. 34: 282-9. PMID 23434408 DOI: 10.1016/j.it.2013.01.004  1
2013 Hu H, Brittain GC, Chang JH, Puebla-Osorio N, Jin J, Zal A, Xiao Y, Cheng X, Chang M, Fu YX, Zal T, Zhu C, Sun SC. OTUD7B controls non-canonical NF-κB activation through deubiquitination of TRAF3. Nature. 494: 371-4. PMID 23334419 DOI: 10.1038/nature11831  1
2012 Zhou XF, Yu J, Chang M, Zhang M, Zhou D, Cammas F, Sun SC. TRIM28 mediates chromatin modifications at the TCRα enhancer and regulates the development of T and natural killer T cells. Proceedings of the National Academy of Sciences of the United States of America. 109: 20083-8. PMID 23169648 DOI: 10.1073/pnas.1214704109  1
2012 Jin J, Xiao Y, Chang JH, Yu J, Hu H, Starr R, Brittain GC, Chang M, Cheng X, Sun SC. The kinase TBK1 controls IgA class switching by negatively regulating noncanonical NF-κB signaling. Nature Immunology. 13: 1101-9. PMID 23023393 DOI: 10.1038/ni.2423  1
2012 Ren T, Dong W, Takahashi Y, Xiang D, Yuan Y, Liu X, Loughran TP, Sun SC, Wang HG, Cheng H. HTLV-2 Tax immortalizes human CD4+ memory T lymphocytes by oncogenic activation and dysregulation of autophagy. The Journal of Biological Chemistry. 287: 34683-93. PMID 22891252 DOI: 10.1074/jbc.M112.377143  1
2012 Cheng H, Ren T, Sun SC. New insight into the oncogenic mechanism of the retroviral oncoprotein Tax. Protein & Cell. 3: 581-9. PMID 22865346 DOI: 10.1007/s13238-012-2047-0  1
2012 Bao M, Hanabuchi S, Facchinetti V, Du Q, Bover L, Plumas J, Chaperot L, Cao W, Qin J, Sun SC, Liu YJ. CD2AP/SHIP1 complex positively regulates plasmacytoid dendritic cell receptor signaling by inhibiting the E3 ubiquitin ligase Cbl. Journal of Immunology (Baltimore, Md. : 1950). 189: 786-92. PMID 22706086 DOI: 10.4049/jimmunol.1200887  1
2012 Chang JH, Xiao Y, Hu H, Jin J, Yu J, Zhou X, Wu X, Johnson HM, Akira S, Pasparakis M, Cheng X, Sun SC. Ubc13 maintains the suppressive function of regulatory T cells and prevents their conversion into effector-like T cells. Nature Immunology. 13: 481-90. PMID 22484734 DOI: 10.1038/ni.2267  1
2012 Sun SC. The noncanonical NF-κB pathway. Immunological Reviews. 246: 125-40. PMID 22435551 DOI: 10.1111/j.1600-065X.2011.01088.x  1
2012 Jin W, Chang M, Sun SC. Peli: a family of signal-responsive E3 ubiquitin ligases mediating TLR signaling and T-cell tolerance. Cellular & Molecular Immunology. 9: 113-22. PMID 22307041 DOI: 10.1038/cmi.2011.60  1
2012 Sun SC. Immune receptor signaling: from ubiquitination to NF-κB activation. Cellular & Molecular Immunology. 9: 97-8. PMID 22231553 DOI: 10.1038/cmi.2011.57  1
2011 Zhang M, Lee AJ, Wu X, Sun SC. Regulation of antiviral innate immunity by deubiquitinase CYLD. Cellular & Molecular Immunology. 8: 502-4. PMID 21946435 DOI: 10.1038/cmi.2011.42  1
2011 Chang M, Jin W, Chang JH, Xiao Y, Brittain GC, Yu J, Zhou X, Wang YH, Cheng X, Li P, Rabinovich BA, Hwu P, Sun SC. The ubiquitin ligase Peli1 negatively regulates T cell activation and prevents autoimmunity. Nature Immunology. 12: 1002-9. PMID 21874024 DOI: 10.1038/ni.2090  1
2011 Wu X, Zhang M, Sun SC. Mutual regulation between deubiquitinase CYLD and retroviral oncoprotein Tax. Cell & Bioscience. 1: 27. PMID 21824392 DOI: 10.1186/2045-3701-1-27  1
2011 Chiou SH, Shahi P, Wagner RT, Hu H, Lapteva N, Seethammagari M, Sun SC, Levitt JM, Spencer DM. The E3 ligase c-Cbl regulates dendritic cell activation. Embo Reports. 12: 971-9. PMID 21799517 DOI: 10.1038/embor.2011.143  1
2011 Hu H, Wu X, Jin W, Chang M, Cheng X, Sun SC. Noncanonical NF-kappaB regulates inducible costimulator (ICOS) ligand expression and T follicular helper cell development. Proceedings of the National Academy of Sciences of the United States of America. 108: 12827-32. PMID 21768353 DOI: 10.1073/pnas.1105774108  1
2011 Cheng CS, Feldman KE, Lee J, Verma S, Huang DB, Huynh K, Chang M, Ponomarenko JV, Sun SC, Benedict CA, Ghosh G, Hoffmann A. The specificity of innate immune responses is enforced by repression of interferon response elements by NF-κB p50. Science Signaling. 4: ra11. PMID 21343618 DOI: 10.1126/scisignal.2001501  1
2011 Sun SC, Liu ZG. A special issue on NF-κB signaling and function. Cell Research. 21: 1-2. PMID 21196938 DOI: 10.1038/cr.2011.1  1
2011 Sun SC. Non-canonical NF-κB signaling pathway. Cell Research. 21: 71-85. PMID 21173796 DOI: 10.1038/cr.2010.177  1
2011 Sun SC, Cesarman E. NF-κB as a target for oncogenic viruses. Current Topics in Microbiology and Immunology. 349: 197-244. PMID 20845110 DOI: 10.1007/82_2010_108  1
2010 Espinosa L, Cathelin S, D'Altri T, Trimarchi T, Statnikov A, Guiu J, Rodilla V, Inglés-Esteve J, Nomdedeu J, Bellosillo B, Besses C, Abdel-Wahab O, Kucine N, Sun SC, Song G, et al. The Notch/Hes1 pathway sustains NF-κB activation through CYLD repression in T cell leukemia Cancer Cell. 18: 268-281. PMID 20832754 DOI: 10.1016/j.ccr.2010.08.006  1
2010 Peng B, Ling J, Lee AJ, Wang Z, Chang Z, Jin W, Kang Y, Zhang R, Shim D, Wang H, Fleming JB, Zheng H, Sun SC, Chiao PJ. Defective feedback regulation of NF-kappaB underlies Sjogren's syndrome in mice with mutated kappaB enhancers of the IkappaBalpha promoter. Proceedings of the National Academy of Sciences of the United States of America. 107: 15193-8. PMID 20696914 DOI: 10.1073/pnas.1005533107  1
2010 Sun SC. Controlling the fate of NIK: a central stage in noncanonical NF-kappaB signaling. Science Signaling. 3: pe18. PMID 20501935 DOI: 10.1126/scisignal.3123pe18  1
2010 Nurieva RI, Zheng S, Jin W, Chung Y, Zhang Y, Martinez GJ, Reynolds JM, Wang SL, Lin X, Sun SC, Lozano G, Dong C. The E3 ubiquitin ligase GRAIL regulates T cell tolerance and regulatory T cell function by mediating T cell receptor-CD3 degradation. Immunity. 32: 670-80. PMID 20493730 DOI: 10.1016/j.immuni.2010.05.002  1
2010 Lee AJ, Wu X, Cheng H, Zhou X, Cheng X, Sun SC. CARMA1 regulation of regulatory T cell development involves modulation of interleukin-2 receptor signaling. The Journal of Biological Chemistry. 285: 15696-703. PMID 20233721 DOI: 10.1074/jbc.M109.095190  1
2010 Lee AJ, Zhou X, Chang M, Hunzeker J, Bonneau RH, Zhou D, Sun SC. Regulation of natural killer T-cell development by deubiquitinase CYLD. The Embo Journal. 29: 1600-12. PMID 20224552 DOI: 10.1038/emboj.2010.31  1
2010 Arima K, Watanabe N, Hanabuchi S, Chang M, Sun SC, Liu YJ. Distinct signal codes generate dendritic cell functional plasticity. Science Signaling. 3: ra4. PMID 20086239 DOI: 10.1126/scisignal.2000567  1
2010 Tang H, Park S, Sun SC, Trumbly R, Ren G, Tsung E, Yeung KC. RKIP inhibits NF-kappaB in cancer cells by regulating upstream signaling components of the IkappaB kinase complex. Febs Letters. 584: 662-8. PMID 20043910 DOI: 10.1016/j.febslet.2009.12.051  1
2010 Sun SC. CYLD: A tumor suppressor deubiquitinase regulating NF-B activation and diverse biological processes Cell Death and Differentiation. 17: 25-34. PMID 19373246 DOI: 10.1038/cdd.2009.43  1
2009 Wu X, Yamamoto M, Akira S, Sun SC. Regulation of hematopoiesis by the K63-specific ubiquitin-conjugating enzyme Ubc13. Proceedings of the National Academy of Sciences of the United States of America. 106: 20836-41. PMID 19926860 DOI: 10.1073/pnas.0906547106  1
2009 Fontenot D, He H, Hanabuchi S, Nehete PN, Zhang M, Chang M, Nehete B, Wang YH, Wang YH, Ma ZM, Lee HC, Ziegler SF, Courtney AN, Miller CJ, Sun SC, et al. TSLP production by epithelial cells exposed to immunodeficiency virus triggers DC-mediated mucosal infection of CD4+ T cells. Proceedings of the National Academy of Sciences of the United States of America. 106: 16776-81. PMID 19805372 DOI: 10.1073/pnas.0907347106  1
2009 Chang M, Jin W, Sun SC. Peli1 facilitates TRIF-dependent Toll-like receptor signaling and proinflammatory cytokine production. Nature Immunology. 10: 1089-95. PMID 19734906 DOI: 10.1038/ni.1777  1
2009 Jin W, Zhou XF, Yu J, Cheng X, Sun SC. Regulation of Th17 cell differentiation and EAE induction by MAP3K NIK. Blood. 113: 6603-10. PMID 19411637 DOI: 10.1182/blood-2008-12-192914  1
2009 Chang M, Lee AJ, Fitzpatrick L, Zhang M, Sun SC. NF-kappa B1 p105 regulates T cell homeostasis and prevents chronic inflammation. Journal of Immunology (Baltimore, Md. : 1950). 182: 3131-8. PMID 19234210 DOI: 10.4049/jimmunol.0803637  1
2009 Zhang M, Jin W, Zhou X, Yu J, Lee AJ, Sun SC. Deregulation of Tpl2 and NF-kappaB signaling and induction of macrophage apoptosis by the anti-depressant drug lithium. Cellular Signalling. 21: 559-66. PMID 19159680 DOI: 10.1016/j.cellsig.2008.12.010  1
2008 Sun SC, Ley SC. New insights into NF-kappaB regulation and function. Trends in Immunology. 29: 469-78. PMID 18775672 DOI: 10.1016/j.it.2008.07.003  1
2008 Sun SC. Deubiquitylation and regulation of the immune response. Nature Reviews. Immunology. 8: 501-11. PMID 18535581 DOI: 10.1038/nri2337  1
2008 Zhang M, Wu X, Lee AJ, Jin W, Chang M, Wright A, Imaizumi T, Sun SC. Regulation of IkappaB kinase-related kinases and antiviral responses by tumor suppressor CYLD. The Journal of Biological Chemistry. 283: 18621-6. PMID 18467330 DOI: 10.1074/jbc.M801451200  1
2008 Jin W, Chang M, Paul EM, Babu G, Lee AJ, Reiley W, Wright A, Zhang M, You J, Sun SC. Deubiquitinating enzyme CYLD negatively regulates RANK signaling and osteoclastogenesis in mice. The Journal of Clinical Investigation. 118: 1858-66. PMID 18382763 DOI: 10.1172/JCI34257  1
2007 Wright A, Reiley WW, Chang M, Jin W, Lee AJ, Zhang M, Sun SC. Regulation of early wave of germ cell apoptosis and spermatogenesis by deubiquitinating enzyme CYLD. Developmental Cell. 13: 705-16. PMID 17981138 DOI: 10.1016/j.devcel.2007.09.007  1
2007 Reiley WW, Jin W, Lee AJ, Wright A, Wu X, Tewalt EF, Leonard TO, Norbury CC, Fitzpatrick L, Zhang M, Sun SC. Deubiquitinating enzyme CYLD negatively regulates the ubiquitin-dependent kinase Tak1 and prevents abnormal T cell responses. The Journal of Experimental Medicine. 204: 1475-85. PMID 17548520 DOI: 10.1084/jem.20062694  1
2007 Jin W, Reiley WR, Lee AJ, Wright A, Wu X, Zhang M, Sun SC. Deubiquitinating enzyme CYLD regulates the peripheral development and naive phenotype maintenance of B cells. The Journal of Biological Chemistry. 282: 15884-93. PMID 17392286 DOI: 10.1074/jbc.M609952200  1
2007 Wu X, Sun SC. Retroviral oncoprotein Tax deregulates NF-kappaB by activating Tak1 and mediating the physical association of Tak1-IKK. Embo Reports. 8: 510-5. PMID 17363973 DOI: 10.1038/sj.embor.7400931  1
2007 Harhaj NS, Sun SC, Harhaj EW. Activation of NF-kappa B by the human T cell leukemia virus type I Tax oncoprotein is associated with ubiquitin-dependent relocalization of I kappa B kinase. The Journal of Biological Chemistry. 282: 4185-92. PMID 17145747 DOI: 10.1074/jbc.M611031200  1
2006 Babu G, Waterfield M, Chang M, Wu X, Sun SC. Deregulated activation of oncoprotein kinase Tpl2/Cot in HTLV-I-transformed T cells. The Journal of Biological Chemistry. 281: 14041-7. PMID 16565081 DOI: 10.1074/jbc.M512375200  1
2006 Reiley WW, Zhang M, Jin W, Losiewicz M, Donohue KB, Norbury CC, Sun SC. Regulation of T cell development by the deubiquitinating enzyme CYLD. Nature Immunology. 7: 411-7. PMID 16501569 DOI: 10.1038/ni1315  1
2006 Babu GR, Jin W, Norman L, Waterfield M, Chang M, Wu X, Zhang M, Sun SC. Phosphorylation of NF-kappaB1/p105 by oncoprotein kinase Tpl2: implications for a novel mechanism of Tpl2 regulation. Biochimica Et Biophysica Acta. 1763: 174-81. PMID 16448710 DOI: 10.1016/j.bbamcr.2005.12.010  1
2006 Zhang W, Hirschler-Laszkiewicz I, Tong Q, Conrad K, Sun SC, Penn L, Barber DL, Stahl R, Carey DJ, Cheung JY, Miller BA. TRPM2 is an ion channel that modulates hematopoietic cell death through activation of caspases and PARP cleavage. American Journal of Physiology. Cell Physiology. 290: C1146-59. PMID 16306129 DOI: 10.1152/ajpcell.00205.2005  1
2006 Liang C, Zhang M, Sun SC. beta-TrCP binding and processing of NF-kappaB2/p100 involve its phosphorylation at serines 866 and 870. Cellular Signalling. 18: 1309-17. PMID 16303288 DOI: 10.1016/j.cellsig.2005.10.011  1
2005 Sun SC, Yamaoka S. Activation of NF-kappaB by HTLV-I and implications for cell transformation. Oncogene. 24: 5952-64. PMID 16155602 DOI: 10.1038/sj.onc.1208969  1
2005 Reiley W, Zhang M, Wu X, Granger E, Sun SC. Regulation of the deubiquitinating enzyme CYLD by IkappaB kinase gamma-dependent phosphorylation. Molecular and Cellular Biology. 25: 3886-95. PMID 15870263 DOI: 10.1128/MCB.25.10.3886-3895.2005  1
2005 Harhaj EW, Harhaj NS, Grant C, Mostoller K, Alefantis T, Sun SC, Wigdahl B. Human T cell leukemia virus type I Tax activates CD40 gene expression via the NF-kappa B pathway. Virology. 333: 145-58. PMID 15708600 DOI: 10.1016/j.virol.2004.12.008  1
2005 Morrison MD, Reiley W, Zhang M, Sun SC. An atypical tumor necrosis factor (TNF) receptor-associated factor-binding motif of B cell-activating factor belonging to the TNF family (BAFF) receptor mediates induction of the noncanonical NF-kappaB signaling pathway. The Journal of Biological Chemistry. 280: 10018-24. PMID 15644327 DOI: 10.1074/jbc.M413634200  1
2004 Reiley W, Zhang M, Sun SC. Negative regulation of JNK signaling by the tumor suppressor CYLD. The Journal of Biological Chemistry. 279: 55161-7. PMID 15496400 DOI: 10.1074/jbc.M411049200  1
2004 Waterfield M, Jin W, Reiley W, Zhang M, Sun SC. IkappaB kinase is an essential component of the Tpl2 signaling pathway. Molecular and Cellular Biology. 24: 6040-8. PMID 15199157 DOI: 10.1128/MCB.24.13.6040-6048.2004  1
2004 Xiao G, Fong A, Sun SC. Induction of p100 processing by NF-kappaB-inducing kinase involves docking IkappaB kinase alpha (IKKalpha) to p100 and IKKalpha-mediated phosphorylation. The Journal of Biological Chemistry. 279: 30099-105. PMID 15140882 DOI: 10.1074/jbc.M401428200  1
2004 Liao G, Zhang M, Harhaj EW, Sun SC. Regulation of the NF-kappaB-inducing kinase by tumor necrosis factor receptor-associated factor 3-induced degradation. The Journal of Biological Chemistry. 279: 26243-50. PMID 15084608 DOI: 10.1074/jbc.M403286200  1
2003 Cvijic ME, Xiao G, Sun SC. Study of T-cell signaling by somatic cell mutagenesis and complementation cloning. Journal of Immunological Methods. 278: 293-304. PMID 12957416 DOI: 10.1016/S0022-1759(03)00191-1  1
2003 Liao G, Sun SC. Regulation of NF-kappaB2/p100 processing by its nuclear shuttling. Oncogene. 22: 4868-74. PMID 12894228 DOI: 10.1038/sj.onc.1206761  1
2003 Sun SC, Xiao G. Deregulation of NF-kappaB and its upstream kinases in cancer. Cancer Metastasis Reviews. 22: 405-22. PMID 12884915 DOI: 10.1023/A:1023733231406  1
2003 Waterfield MR, Zhang M, Norman LP, Sun SC. NF-kappaB1/p105 regulates lipopolysaccharide-stimulated MAP kinase signaling by governing the stability and function of the Tpl2 kinase. Molecular Cell. 11: 685-94. PMID 12667451 DOI: 10.1016/S1097-2765(03)00070-4  1
2002 Fong A, Zhang M, Neely J, Sun SC. S9, a 19 S proteasome subunit interacting with ubiquitinated NF-kappaB2/p100. The Journal of Biological Chemistry. 277: 40697-702. PMID 12185077 DOI: 10.1074/jbc.M205330200  1
2002 Fong A, Sun SC. Genetic evidence for the essential role of beta-transducin repeat-containing protein in the inducible processing of NF-kappa B2/p100. The Journal of Biological Chemistry. 277: 22111-4. PMID 11994270 DOI: 10.1074/jbc.C200151200  1
2001 Xiao G, Cvijic ME, Fong A, Harhaj EW, Uhlik MT, Waterfield M, Sun SC. Retroviral oncoprotein tax induces processing of NF-κB2/p100 in T cells: Evidence for the involvement of IKKα Embo Journal. 20: 6805-6815. PMID 11726516 DOI: 10.1093/emboj/20.23.6805  1
2001 Rivera-Walsh I, Waterfield M, Xiao G, Fong A, Sun SC. NF-κB Signaling Pathway Governs TRAIL Gene Expression and Human T-cell Leukemia Virus-I Tax-induced T-cell Death Journal of Biological Chemistry. 276: 40385-40388. PMID 11553609 DOI: 10.1074/jbc.C100501200  1
2001 Senftleben U, Cao Y, Xiao G, Greten FR, Krähn G, Bonizzi G, Chen Y, Hu Y, Fong A, Sun SC, Karin M. Activation by IKKalpha of a second, evolutionary conserved, NF-kappa B signaling pathway. Science (New York, N.Y.). 293: 1495-9. PMID 11520989 DOI: 10.1126/science.1062677  1
2001 Xiao G, Harhaj EW, Sun SC. NF-κB-inducing kinase regulates the processing of NF-κB2 p100 Molecular Cell. 7: 401-409. PMID 11239468 DOI: 10.1016/S1097-2765(01)00187-3  1
2000 Sun SC, Harhaj EW, Xiao G, Good L. Activation of I-κB kinase by the HTLV type 1 Tax protein: Mechanistic insights into the adaptor function of IKKγ Aids Research and Human Retroviruses. 16: 1591-1596. PMID 11080796 DOI: 10.1089/08892220050193001  1
2000 Xiao G, Sun SC. Activation of IKKα and IKKβ through their fusion with HTLV-I tax protein Oncogene. 19: 5198-5203. PMID 11064457 DOI: 10.1038/sj.onc.1203894  1
2000 Xiao G, Harhaj EW, Sun SC. Domain-specific interaction with the IκB kinase (IKK) regulatory subunit IKKγ is an essential step in tax-mediated activation of IKK Journal of Biological Chemistry. 275: 34060-34067. PMID 10906125  1
2000 Xiao G, Sun SC. Negative regulation of the nuclear factor κB-inducing kinase by a cis- acting domain Journal of Biological Chemistry. 275: 21081-21085. PMID 10887201 DOI: 10.1074/jbc.M002552200  1
2000 Rivera-Walsh I, Cvijic ME, Xiao G, Sun SC. The NF-κB signaling pathway is not required for fas ligand gene induction but mediates protection from activation-induced cell death Journal of Biological Chemistry. 275: 25222-25230. PMID 10837465 DOI: 10.1074/jbc.M000444200  1
2000 Harhaj EW, Good L, Xiao G, Uhlik M, Cvijic ME, Rivera-Walsh I, Sun SC. Somatic mutagenesis studies of NF-κB signaling in human T cells: Evidence for an essential role of IKKγ, in NP-κB activation by T-cell costimulatory signals and HTLV-I Tax protein Oncogene. 19: 1448-1456. PMID 10723136 DOI: 10.1038/sj.onc.1203445  1
1999 Sun SC, Ballard DW. Persistent activation of NF-κB by the Tax transforming protein of HTLV-1: Hijacking cellular IκB kinases Oncogene. 18: 6948-6958. PMID 10602469  1
1999 Harhaj EW, Sun SC. IKKγ serves as a docking subunit of the IκB kinase (IKK) and mediates interaction of IKK with the human T-cell leukemia virus tax protein Journal of Biological Chemistry. 274: 22911-22914. PMID 10438454 DOI: 10.1074/jbc.274.33.22911  1
1999 Sun SC, Maggirwar SB, Harhaj EW, Uhlik M. Binding of c-Rel to STAT5 target sequences in HTLV-I-transformed T cells. Oncogene. 18: 1401-9. PMID 10050877 DOI: 10.1038/sj.onc.1202430  1
1998 Rivera I, Harhaj EW, Sun SC. Involvement of NF-AT in type I human T-cell leukemia virus tax-mediated fas ligand promoter transactivation Journal of Biological Chemistry. 273: 22382-22388. PMID 9712859 DOI: 10.1074/jbc.273.35.22382  1
1998 Uhlik M, Good L, Xiao G, Harhaj EW, Zandi E, Karin M, Sun SC. NF-κB-inducing kinase and IκB kinase participate in human T-cell leukemia virus I tax-mediated NF-κB activation Journal of Biological Chemistry. 273: 21132-21136. PMID 9694868 DOI: 10.1074/jbc.273.33.21132  1
1997 Maggirwar SB, Harhaj EW, Sun SC. Regulation of the interleukin-2 CD28-responsive element by NF-ATp and various NF-kappaB/Rel transcription factors. Molecular and Cellular Biology. 17: 2605-14. PMID 9111330  1
1997 Good L, Maggirwar SB, Harhaj EW, Sun SC. Constitutive dephosphorylation and activation of a member of the nuclear factor of activated T cells, NF-AT1, in Tax-expressing and type I human T-cell leukemia virus-infected human T cells. The Journal of Biological Chemistry. 272: 1425-8. PMID 8999806 DOI: 10.1074/jbc.272.3.1425  1
1996 Harhaj EW, Maggirwar SB, Good L, Sun SC. CD28 mediates a potent costimulatory signal for rapid degradation of IkappaBbeta which is associated with accelerated activation of various NF-kappaB/Rel heterodimers. Molecular and Cellular Biology. 16: 6736-43. PMID 8943328  1
1996 Mandal M, Maggirwar SB, Sharma N, Kaufmann SH, Sun SC, Kumar R. Bcl-2 prevents CD95 (Fas/APO-1)-induced degradation of lamin B and poly(ADP-ribose) polymerase and restores the NF-kappaB signaling pathway. The Journal of Biological Chemistry. 271: 30354-9. PMID 8939996 DOI: 10.1074/jbc.271.48.30354  1
1996 Good L, Maggirwar SB, Sun SC. Activation of the IL-2 gene promoter by HTLV-I tax involves induction of NF-AT complexes bound to the CD28-responsive element. The Embo Journal. 15: 3744-50. PMID 8670878  1
1996 Good LF, Maggirwar SB, Kealiher A, Uhlik M, Sun SC. Multiple structural domains within I kappa B alpha are required for its inducible degradation by both cytokines and phosphatase inhibitors. Biochemical and Biophysical Research Communications. 223: 123-8. PMID 8660357 DOI: 10.1006/bbrc.1996.0856  1
1996 Harhaj EW, Maggirwar SB, Sun SC. Inhibition of p105 processing by NF-kappaB proteins in transiently transfected cells. Oncogene. 12: 2385-92. PMID 8649779  1
1996 Sun SC, Elwood J, Greene WC. Both amino- and carboxyl-terminal sequences within IκBα regulate its inducible degradation Molecular and Cellular Biology. 16: 1058-1065. PMID 8622650 DOI: 10.1128/MCB.16.3.1058  1
1995 Maggirwar SB, Harhaj E, Sun SC. Activation of NF-kappa B/Rel by Tax involves degradation of I kappa B alpha and is blocked by a proteasome inhibitor. Oncogene. 11: 993-8. PMID 7675460  1
1995 Sun SC, Maggirwar SB, Harhaj E. Activation of NF-kappa B by phosphatase inhibitors involves the phosphorylation of I kappa B alpha at phosphatase 2A-sensitive sites. The Journal of Biological Chemistry. 270: 18347-51. PMID 7629157 DOI: 10.1074/jbc.270.31.18347  1
1995 Sun SC, Faye I. Transcription of immune genes in the giant silkmoth, Hyalophora cecropia, is augmented by H2O2 and diminished by thiol reagents. European Journal of Biochemistry / Febs. 231: 93-8. PMID 7628488 DOI: 10.1111/j.1432-1033.1995.0093f.x  1
1995 Lindström-Dinnetz I, Sun SC, Faye I. Structure and expression of Hemolin, an insect member of the immunoglobulin gene superfamily. European Journal of Biochemistry / Febs. 230: 920-5. PMID 7601154 DOI: 10.1111/j.1432-1033.1995.tb20637.x  1
1994 Béraud C, Sun SC, Ganchi P, Ballard DW, Greene WC. Human T-cell leukemia virus type I tax associates with and is negatively regulated by the NF-κB2 p100 gene product: Implications for viral latency Molecular and Cellular Biology. 14: 1374-1382. PMID 8289813 DOI: 10.1128/MCB.14.2.1374  1
1994 Sun SC, Ganchi PA, Béraud C, Ballard DW, Greene WC. Autoregulation of the NF-κB transactivator RelA (p65) by multiple cytoplasmic inhibitors containing ankyrin motifs Proceedings of the National Academy of Sciences of the United States of America. 91: 1346-1350. PMID 8108414 DOI: 10.1073/pnas.91.4.1346  1
1994 Sun SC, Elwood J, Béraud C, Greene WC. Human T-cell leukemia virus type I Tax activation of NF-κB/Rel involves phosphorylation and degradation of IκBα and RelA (p65)-mediated induction of the c-rel gene Molecular and Cellular Biology. 14: 7377-7384. PMID 7935451 DOI: 10.1128/MCB.14.11.7377  1
1993 Doerre S, Sista P, Sun SC, Ballard DW, Greene WC. The c-rel protooncogene product represses NF-κB p65-mediated transcriptional activation of the long terminal repeat of type 1 human immunodeficiency virus Proceedings of the National Academy of Sciences of the United States of America. 90: 1023-1027. PMID 8430069 DOI: 10.1073/pnas.90.3.1023  1
1993 Engström Y, Kadalayil L, Sun SC, Samakovlis C, Hultmark D, Faye I. kappa B-like motifs regulate the induction of immune genes in Drosophila. Journal of Molecular Biology. 232: 327-33. PMID 8345514 DOI: 10.1006/jmbi.1993.1392  1
1993 Schmidt O, Faye I, Lindström-Dinnetz I, Sun SC. Specific immune recognition of insect hemolin. Developmental and Comparative Immunology. 17: 195-200. PMID 8325433 DOI: 10.1016/0145-305X(93)90038-R  1
1993 Ganchi PA, Sun SC, Greene WC, Ballard DW. A novel NF-κB complex containing p65 homodimers: Implications for transcriptional control at the level of subunit dimerization Molecular and Cellular Biology. 13: 7826-7835. PMID 8246997 DOI: 10.1128/MCB.13.12.7826  1
1993 Sun SC, Ganchi PA, Ballard DW, Greene WC. NF-κb controls expression of inhibitor iκbα: evidence for an inducible autoregulatory pathway Science. 259: 1912-1915. PMID 8096091 DOI: 10.1126/science.8096091  1
1992 Sun SC, Faye I. Cecropia immunoresponsive factor, an insect immunoresponsive factor with DNA-binding properties similar to nuclear-factor kappa B. European Journal of Biochemistry / Febs. 204: 885-92. PMID 1541299  1
1992 Ganchi PA, Sun SC, Greene WC, Ballard DW. IκB/MAD-3 masks the nuclear localization signal of NF-κB p65 and requires the transactivation domain to inhibit NF-κB p65 DNA binding Molecular Biology of the Cell. 3: 1339-1352. PMID 1493333 DOI: 10.1091/mbc.3.12.1339  1
1992 Sun SC, Faye I. Affinity purification and characterization of CIF, an insect immunoresponsive factor with NF-kappa B-like properties. Comparative Biochemistry and Physiology. B, Comparative Biochemistry. 103: 225-33. PMID 1451434 DOI: 10.1016/0305-0491(92)90436-U  1
1991 Sun SC, Asling B, Faye I. Organization and expression of the immunoresponsive lysozyme gene in the giant silk moth, Hyalophora cecropia. The Journal of Biological Chemistry. 266: 6644-9. PMID 2007608  1
1991 Sun SC, Lindström I, Lee JY, Faye I. Structure and expression of the attacin genes in Hyalophora cecropia. European Journal of Biochemistry / Febs. 196: 247-54. PMID 2001705  1
1991 Sun SC, Linström I, Boman HG, Faye I, Schmidt O. Hemolin, an insect immune protein belonging to the immunoglobulin superfamily Developmental and Comparative Immunology. 15: S100. DOI: 10.1016/0145-305X(91)90326-T  1
1990 Sun SC, Lindström I, Boman HG, Faye I, Schmidt O. Hemolin: an insect-immune protein belonging to the immunoglobulin superfamily. Science (New York, N.Y.). 250: 1729-32. PMID 2270488  1
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