Michael Borchers - Publications

Affiliations: 
Toxicology (Environmental Health) University of Cincinnati, Cincinnati, OH 
Area:
Immunology, Medicine and Surgery, Public Health, Environmental Health

58 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Ojha M, Smith NJ, Devine AJ, Joshi R, Goodman EM, Fan Q, Schuman R, Porollo A, Wells JM, Tiwary E, Batie MR, Gray J, Deshmukh H, Borchers MT, Ammerman SA, et al. Anti-CELA1 antibody KF4 prevents emphysema by inhibiting stretch-mediated remodeling. Jci Insight. 9. PMID 38193533 DOI: 10.1172/jci.insight.169189  0.376
2023 Devine AJ, Smith NJ, Joshi R, Fan Q, Borchers MT, Clair GC, Adkins JN, Varisco BM. Chymotrypsin-like Elastase-1 Mediates Progressive Emphysema in Alpha-1 Antitrypsin Deficiency. Chronic Obstructive Pulmonary Diseases (Miami, Fla.). PMID 37534975 DOI: 10.15326/jcopdf.2023.0416  0.349
2023 Burkes RM, Bailey E, Hwalek T, Osterburg A, Lach L, Panos R, Waggoner SN, Borchers MT. Associations of Smoking, Cytomegalovirus Serostatus, and Natural Killer Cell Phenotypes in Smokers With and At Risk for COPD. Chronic Obstructive Pulmonary Diseases (Miami, Fla.). PMID 37267601 DOI: 10.15326/jcopdf.2022.0382  0.413
2023 Devine AJ, Smith NJ, Joshi R, Fan Q, Borchers MT, Clair GC, Adkins JN, Varisco BM. CELA1 Mediates Progressive Emphysema in Alpha-1 Antitrypsin Deficiency. Research Square. PMID 36865303 DOI: 10.21203/rs.3.rs-2617812/v1  0.335
2020 Rajaram S, Canaday LM, Ochayon DE, Rangel KM, Ali A, Gyurova IE, Krishnamurthy D, Fletcher JS, Reighard SD, Cox A, Weirauch MT, Kottyan LC, Deshmukh H, Zacharias WJ, Borchers MT, et al. The Promise and Peril of Natural Killer Cell Therapies in Pulmonary Infection. Immunity. PMID 32405233 DOI: 10.1016/J.Immuni.2020.04.018  0.369
2020 Shaw B, Borchers M, Zander D, Gupta N. Pulmonary Langerhans Cell Histiocytosis. Seminars in Respiratory and Critical Care Medicine. 41: 269-279. PMID 32279297 DOI: 10.1055/S-0039-1700996  0.503
2020 Knoell DL, Smith D, Bao S, Sapkota M, Wyatt TA, Zweier JL, Flury J, Borchers MT, Knutson M. Imbalance in zinc homeostasis enhances lung Tissue Loss following cigarette smoke exposure. Journal of Trace Elements in Medicine and Biology : Organ of the Society For Minerals and Trace Elements (Gms). 60: 126483. PMID 32155573 DOI: 10.1016/J.Jtemb.2020.126483  0.39
2020 Choi W, Choe S, Lin J, Borchers MT, Kosmider B, Vassallo R, Limper AH, Lau GW. Exendin-4 restores airway mucus homeostasis through the GLP1R-PKA-PPARγ-FOXA2-phosphatase signaling. Mucosal Immunology. PMID 32034274 DOI: 10.1038/s41385-020-0262-1  0.417
2020 Osterburg AR, Lach L, Panos RJ, Borchers MT. Unique natural killer cell subpopulations are associated with exacerbation risk in chronic obstructive pulmonary disease. Scientific Reports. 10: 1238. PMID 31988425 DOI: 10.1038/s41598-020-58326-7  0.502
2020 Liu H, Osterburg AR, Flury J, Swank Z, McGraw DW, Gupta N, Wikenheiser-Brokamp KA, Kumar A, Tazi A, Inoue Y, Hirose M, McCormack FX, Borchers M. MAPK mutations and cigarette smoke promote the pathogenesis of pulmonary Langerhans cell histiocytosis. Jci Insight. PMID 31961828 DOI: 10.1172/jci.insight.132048  0.47
2019 Wellmerling JH, Chang SW, Kim E, Osman WH, Boyaka PN, Borchers MT, Cormet-Boyaka E. Reduced expression of the Ion channel CFTR contributes to airspace enlargement as a consequence of aging and in response to cigarette smoke in mice. Respiratory Research. 20: 200. PMID 31477092 DOI: 10.1186/s12931-019-1170-3  0.434
2019 Suzuki T, McCarthy C, Carey B, Borchers M, Beck D, Wikenheiser-Brokamp KA, Black D, Chalk C, Trapnell BC. Increased Pulmonary GM-CSF Causes Alveolar Macrophage Accumulation: Mechanistic Implications for Desquamative Interstitial Pneumonitis. American Journal of Respiratory Cell and Molecular Biology. PMID 31310562 DOI: 10.1165/Rcmb.2018-0294Oc  0.533
2018 Osterburg AR, Lach L, Panos RJ, Borchers MT. Peripheral Blood Natural Killer Cell Phenotypes Associated with Exacerbation Risk in Patients with Chronic Obstructive Pulmonary Disease. Annals of the American Thoracic Society. 15: S288-S289. PMID 30759007 DOI: 10.1513/AnnalsATS.201806-396MG  0.371
2018 Liu H, Osterburg AR, Flury J, Huang S, McCormack FX, Cormier SA, Borchers MT. NKG2D is Required for Regulation of Lung Pathology and Dendritic Cell Function Following RSV Infection. The Journal of Infectious Diseases. PMID 29554301 DOI: 10.1093/infdis/jiy151  0.411
2018 MILLER J, BORCHERS M, OSTERBURG A. CORRELATION OF SPECIFIC NK CELL RECEPTOR LIGANDS WITH COPD SEVERITY Chest. 154: 766A. DOI: 10.1016/J.Chest.2018.08.691  0.447
2017 Li C, Liu X, Liu Y, Zhang E, Medepalli K, Masuda K, Li N, Kopras EJ, Kwiatkowski DJ, Borchers MT, Wikenheiser-Brokamp KA, Osterburg A, Mays M, Sun Y, Plas DR, et al. Tuberin Regulates Prostaglandin Receptor-mediated Viability, via Rheb, in mTORC1-hyperactive Cells. Molecular Cancer Research : McR. PMID 28710231 DOI: 10.1158/1541-7786.Mcr-17-0077  0.369
2017 Liu H, Jakubzick C, Osterburg AR, Nelson RL, Gupta N, McCormack FX, Borchers MT. Dendritic Cell Trafficking and Function in Rare Lung Diseases. American Journal of Respiratory Cell and Molecular Biology. PMID 28586276 DOI: 10.1165/Rcmb.2017-0051Ps  0.372
2016 Osterburg AR, Nelson RL, Yaniv BZ, Foot R, Donica WR, Nashu MA, Liu H, Wikenheiser-Brokamp KA, Moss J, Gupta N, McCormack FX, Borchers MT. NK cell activating receptor ligand expression in lymphangioleiomyomatosis is associated with lung function decline. Jci Insight. 1: e87270. PMID 27734028 DOI: 10.1172/Jci.Insight.87270  0.408
2016 Wortham BW, Eppert BL, Flury JL, Garcia SM, Donica WR, Osterburg A, Joyce-Shaikh B, Cua DJ, Borchers MT. Cutting Edge: CLEC5A Mediates Macrophage Function and Chronic Obstructive Pulmonary Disease Pathologies. Journal of Immunology (Baltimore, Md. : 1950). PMID 26927798 DOI: 10.4049/jimmunol.1500978  0.492
2014 Hassett DJ, Borchers MT, Panos RJ. Chronic obstructive pulmonary disease (COPD): Evaluation from clinical, immunological and bacterial pathogenesis perspectives Journal of Microbiology. 52: 211-226. PMID 24585052 DOI: 10.1007/S12275-014-4068-2  0.514
2013 Wortham BW, Eppert BL, Flury JL, Morgado Garcia S, Borchers MT. TLR and NKG2D signaling pathways mediate CS-induced pulmonary pathologies. Plos One. 8: e78735. PMID 24130907 DOI: 10.1371/journal.pone.0078735  0.528
2013 Eppert BL, Wortham BW, Flury JL, Borchers MT. Functional characterization of T cell populations in a mouse model of chronic obstructive pulmonary disease. Journal of Immunology (Baltimore, Md. : 1950). 190: 1331-40. PMID 23264660 DOI: 10.4049/jimmunol.1202442  0.562
2013 Orozco-Levi M, Ramírez-Sarmiento A, Borchers M, Murta-Nascimento C, Macià F, Casado B, Polo M, Caballero-Benitez A, Diaz-Quijano F, Gelabert A. Lack of MICA Expression Predicts a Worse Prognosis in Patients with Bladder Cancer Open Journal of Pathology. 3: 41-50. DOI: 10.4236/Ojpathology.2013.31008  0.37
2012 Wortham BW, Eppert BL, Motz GT, Flury JL, Orozco-Levi M, Hoebe K, Panos RJ, Maxfield M, Glasser SW, Senft AP, Raulet DH, Borchers MT. NKG2D mediates NK cell hyperresponsiveness and influenza-induced pathologies in a mouse model of chronic obstructive pulmonary disease. Journal of Immunology (Baltimore, Md. : 1950). 188: 4468-75. PMID 22467655 DOI: 10.4049/Jimmunol.1102643  0.763
2010 Motz GT, Eppert BL, Wortham BW, Amos-Kroohs RM, Flury JL, Wesselkamper SC, Borchers MT. Chronic cigarette smoke exposure primes NK cell activation in a mouse model of chronic obstructive pulmonary disease. Journal of Immunology (Baltimore, Md. : 1950). 184: 4460-9. PMID 20228194 DOI: 10.4049/Jimmunol.0903654  0.778
2010 Eppert BL, Motz GT, Wortham BW, Flury JL, Borchers MT. CCR7 deficiency leads to leukocyte activation and increased clearance in response to pulmonary Pseudomonas aeruginosa infection. Infection and Immunity. 78: 2099-107. PMID 20176793 DOI: 10.1128/Iai.00962-09  0.749
2010 Motz GT, Eppert BL, Wesselkamper SC, Flury JL, Borchers MT. Chronic cigarette smoke exposure generates pathogenic T cells capable of driving COPD-like disease in Rag2-/- mice. American Journal of Respiratory and Critical Care Medicine. 181: 1223-33. PMID 20133926 DOI: 10.1164/Rccm.200910-1485Oc  0.764
2009 Borchers MT, Wesselkamper SC, Deshmukh H, Beckman E, Medvedovic M, Sartor M, Leikauf GD. The role of T cells in the regulation of acrolein-induced pulmonary inflammation and epithelial-cell pathology. Research Report (Health Effects Institute). 5-29. PMID 20218173  0.532
2009 Caldwell CC, Chen Y, Goetzmann HS, Hao Y, Borchers MT, Hassett DJ, Young LR, Mavrodi D, Thomashow L, Lau GW. Pseudomonas aeruginosa exotoxin pyocyanin causes cystic fibrosis airway pathogenesis. The American Journal of Pathology. 175: 2473-88. PMID 19893030 DOI: 10.2353/Ajpath.2009.090166  0.541
2009 Deshmukh HS, McLachlan A, Atkinson JJ, Hardie WD, Korfhagen TR, Dietsch M, Liu Y, Di PY, Wesselkamper SC, Borchers MT, Leikauf GD. Matrix metalloproteinase-14 mediates a phenotypic shift in the airways to increase mucin production. American Journal of Respiratory and Critical Care Medicine. 180: 834-45. PMID 19661247 DOI: 10.1164/Rccm.200903-0328Oc  0.333
2009 Ganguly K, Depner M, Fattman C, Bein K, Oury TD, Wesselkamper SC, Borchers MT, Schreiber M, Gao F, von Mutius E, Kabesch M, Leikauf GD, Schulz H. Superoxide dismutase 3, extracellular (SOD3) variants and lung function. Physiological Genomics. 37: 260-7. PMID 19318538 DOI: 10.1152/Physiolgenomics.90363.2008  0.37
2009 Borchers MT, Wesselkamper SC, Curull V, Ramirez-Sarmiento A, Sánchez-Font A, Garcia-Aymerich J, Coronell C, Lloreta J, Agusti AG, Gea J, Howington JA, Reed MF, Starnes SL, Harris NL, Vitucci M, et al. Sustained CTL activation by murine pulmonary epithelial cells promotes the development of COPD-like disease. The Journal of Clinical Investigation. 119: 636-49. PMID 19197141 DOI: 10.1172/Jci34462  0.762
2009 Bein K, Wesselkamper SC, Liu X, Dietsch M, Majumder N, Concel VJ, Medvedovic M, Sartor MA, Henning LN, Venditto C, Borchers MT, Barchowsky A, Weaver TE, Tichelaar JW, Prows DR, et al. Surfactant-associated protein B is critical to survival in nickel-induced injury in mice. American Journal of Respiratory Cell and Molecular Biology. 41: 226-36. PMID 19131640 DOI: 10.1165/Rcmb.2008-0317Oc  0.315
2008 Motz GT, Eppert BL, Sun G, Wesselkamper SC, Linke MJ, Deka R, Borchers MT. Persistence of lung CD8 T cell oligoclonal expansions upon smoking cessation in a mouse model of cigarette smoke-induced emphysema. Journal of Immunology (Baltimore, Md. : 1950). 181: 8036-43. PMID 19017996 DOI: 10.4049/Jimmunol.181.11.8036  0.755
2008 Wesselkamper SC, Eppert BL, Motz GT, Lau GW, Hassett DJ, Borchers MT. NKG2D is critical for NK cell activation in host defense against Pseudomonas aeruginosa respiratory infection. Journal of Immunology (Baltimore, Md. : 1950). 181: 5481-9. PMID 18832705 DOI: 10.4049/Jimmunol.181.8.5481  0.757
2008 Borchers MT, Wesselkamper SC, Eppert BL, Motz GT, Sartor MA, Tomlinson CR, Medvedovic M, Tichelaar JW. Nonredundant functions of alphabeta and gammadelta T cells in acrolein-induced pulmonary pathology. Toxicological Sciences : An Official Journal of the Society of Toxicology. 105: 188-99. PMID 18515264 DOI: 10.1093/Toxsci/Kfn106  0.743
2007 Borchers MT, Wesselkamper SC, Harris NL, Deshmukh H, Beckman E, Vitucci M, Tichelaar JW, Leikauf GD. CD8+ T cells contribute to macrophage accumulation and airspace enlargement following repeated irritant exposure. Experimental and Molecular Pathology. 83: 301-10. PMID 17950725 DOI: 10.1016/J.Yexmp.2007.08.020  0.498
2007 Ochkur S, Biechele T, Jacobsen E, McElhinney B, Protheroe C, Pero R, Borchers M, O'Neill K, Colbert D, McGarry M, Janssen-Heininger Y, Irvin C, Shen H, Lee J, Lee N. Co-Expression of IL-5 and Eotaxin-2 in Mice Creates a Novel and Eosinophil-dependent Pulmonary Model of Respiratory Inflammation Characteristic of Human Disease Journal of Allergy and Clinical Immunology. 119: S151. DOI: 10.1016/J.Jaci.2006.11.529  0.35
2006 Borchers MT, Harris NL, Wesselkamper SC, Zhang S, Chen Y, Young L, Lau GW. The NKG2D-activating receptor mediates pulmonary clearance of Pseudomonas aeruginosa. Infection and Immunity. 74: 2578-86. PMID 16622193 DOI: 10.1128/IAI.74.5.2578-2586.2006  0.498
2006 Young LR, Borchers MT, Allen HL, Gibbons RS, McCormack FX. Lung-restricted macrophage activation in the pearl mouse model of Hermansky-Pudlak syndrome. Journal of Immunology (Baltimore, Md. : 1950). 176: 4361-8. PMID 16547274  0.31
2006 Borchers MT, Harris NL, Wesselkamper SC, Vitucci M, Cosman D. NKG2D ligands are expressed on stressed human airway epithelial cells. American Journal of Physiology. Lung Cellular and Molecular Physiology. 291: L222-31. PMID 16473864 DOI: 10.1152/ajplung.00327.2005  0.445
2006 Wesselkamper SC, McDowell SA, Medvedovic M, Dalton TP, Deshmukh HS, Sartor MA, Case LM, Henning LN, Borchers MT, Tomlinson CR, Prows DR, Leikauf GD. The role of metallothionein in the pathogenesis of acute lung injury. American Journal of Respiratory Cell and Molecular Biology. 34: 73-82. PMID 16166738 DOI: 10.1165/Rcmb.2005-0248Oc  0.314
2003 Lyerla TA, Rusiniak ME, Borchers M, Jahreis G, Tan J, Ohtake P, Novak EK, Swank RT. Aberrant lung structure, composition, and function in a murine model of Hermansky-Pudlak syndrome. American Journal of Physiology. Lung Cellular and Molecular Physiology. 285: L643-53. PMID 12777251 DOI: 10.1152/Ajplung.00024.2003  0.466
2003 Shen HH, Ochkur SI, McGarry MP, Crosby JR, Hines EM, Borchers MT, Wang H, Biechelle TL, O'Neill KR, Ansay TL, Colbert DC, Cormier SA, Justice JP, Lee NA, Lee JJ. A causative relationship exists between eosinophils and the development of allergic pulmonary pathologies in the mouse. Journal of Immunology (Baltimore, Md. : 1950). 170: 3296-305. PMID 12626589  0.406
2003 Borchers MT, Biechele T, Justice JP, Ansay T, Cormier S, Mancino V, Wilkie TM, Simon MI, Lee NA, Lee JJ. Methacholine-induced airway hyperresponsiveness is dependent on Galphaq signaling. American Journal of Physiology. Lung Cellular and Molecular Physiology. 285: L114-20. PMID 12611815 DOI: 10.1152/Ajplung.00322.2002  0.307
2003 Justice JP, Borchers MT, Crosby JR, Hines EM, Shen HH, Ochkur SI, McGarry MP, Lee NA, Lee JJ. Ablation of eosinophils leads to a reduction of allergen-induced pulmonary pathology. American Journal of Physiology. Lung Cellular and Molecular Physiology. 284: L169-78. PMID 12388345 DOI: 10.1152/ajplung.00260.2002  0.467
2002 Leikauf GD, Borchers MT, Prows DR, Simpson LG. Mucin apoprotein expression in COPD. Chest. 121: 166S-182S. PMID 12010847 DOI: 10.1378/Chest.121.5_Suppl.166S  0.359
2002 McGarry MP, Borchers M, Novak EK, Lee NA, Ohtake PJ, Lee JJ, Swank RT. Pulmonary pathologies in pallid mice result from nonhematopoietic defects. Experimental and Molecular Pathology. 72: 213-20. PMID 12009785 DOI: 10.1006/Exmp.2002.2431  0.348
2002 Justice JP, Crosby J, Borchers MT, Tomkinson A, Lee JJ, Lee NA. CD4(+) T cell-dependent airway mucus production occurs in response to IL-5 expression in lung. American Journal of Physiology. Lung Cellular and Molecular Physiology. 282: L1066-74. PMID 11943672 DOI: 10.1152/ajplung.00195.2001  0.356
2002 Crosby JR, Cieslewicz G, Borchers M, Hines E, Carrigan P, Lee JJ, Lee NA. Early phase bronchoconstriction in the mouse requires allergen-specific IgG. Journal of Immunology (Baltimore, Md. : 1950). 168: 4050-4. PMID 11937563 DOI: 10.4049/jimmunol.168.8.4050  0.333
2002 Borchers MT, Justice PJ, Ansay T, Mancino V, McGarry MP, Crosby J, Simon MI, Lee NA, Lee JJ. Gq signaling is required for allergen-induced pulmonary eosinophilia. Journal of Immunology (Baltimore, Md. : 1950). 168: 3543-9. PMID 11907117 DOI: 10.4049/Jimmunol.168.7.3543  0.39
2002 Justice JP, Borchers MT, Lee JJ, Rowan WH, Shibata Y, Van Scott MR. Ragweed-induced expression of GATA-3, IL-4, and IL-5 by eosinophils in the lungs of allergic C57BL/6J mice. American Journal of Physiology. Lung Cellular and Molecular Physiology. 282: L302-9. PMID 11792635 DOI: 10.1152/ajplung.00158.2001  0.332
2002 Crosby JR, Shen HH, Borchers MT, Justice JP, Ansay T, Lee JJ, Lee NA. Ectopic expression of IL-5 identifies an additional CD4(+) T cell mechanism of airway eosinophil recruitment. American Journal of Physiology. Lung Cellular and Molecular Physiology. 282: L99-108. PMID 11741821 DOI: 10.1152/AJPLUNG.2002.282.1.L99  0.432
2002 Shen HJ, Justice JP, Borchers MT, Crosby JR, Hines E, O'Neill K, Ansay T, Lee NA, Lee JJ. A direct causative relationship exists between eosinophils and the development of allergen-mediated pulmonary pathologies, including airway mucus production and the development of AHR Journal of Allergy and Clinical Immunology. 109: S226-S226. DOI: 10.1016/S0091-6749(02)81818-8  0.3
2001 Borchers MT, Crosby J, Justice P, Farmer S, Hines E, Lee JJ, Lee NA. Intrinsic AHR in IL-5 transgenic mice is dependent on CD4(+) cells and CD49d-mediated signaling. American Journal of Physiology. Lung Cellular and Molecular Physiology. 281: L653-9. PMID 11504693 DOI: 10.1152/AJPLUNG.2001.281.3.L653  0.306
2001 Denzler KL, Borchers MT, Crosby JR, Cieslewicz G, Hines EM, Justice JP, Cormier SA, Lindenberger KA, Song W, Wu W, Hazen SL, Gleich GJ, Lee JJ, Lee NA. Extensive eosinophil degranulation and peroxidase-mediated oxidation of airway proteins do not occur in a mouse ovalbumin-challenge model of pulmonary inflammation. Journal of Immunology (Baltimore, Md. : 1950). 167: 1672-82. PMID 11466391 DOI: 10.4049/jimmunol.167.3.1672  0.344
1999 Borchers MT, Wesselkamper S, Wert SE, Shapiro SD, Leikauf GD. Monocyte inflammation augments acrolein-induced Muc5ac expression in mouse lung. The American Journal of Physiology. 277: L489-97. PMID 10484456 DOI: 10.1152/Ajplung.1999.277.3.L489  0.39
1998 Borchers MT, Wert SE, Leikauf GD. Acrolein-induced MUC5ac expression in rat airways. American Journal of Physiology. Lung Cellular and Molecular Physiology. 274: L573-L581. PMID 29586215 DOI: 10.1152/Ajplung.1998.274.4.L573  0.363
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