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Year Citation  Score
2001 Wiradjaja F, Ooms LM, Whisstock JC, McColl B, Helfenbaum L, Sambrook JF, Gething MJ, Mitchell CA. The yeast inositol polyphosphate 5-phosphatase Inp54p localizes to the endoplasmic reticulum via a C-terminal hydrophobic anchoring tail: regulation of secretion from the endoplasmic reticulum. The Journal of Biological Chemistry. 276: 7643-53. PMID 11116155 DOI: 10.1074/jbc.M010471200  0.527
2000 Ooms LM, McColl BK, Wiradjaja F, Wijayaratnam AP, Gleeson P, Gething MJ, Sambrook J, Mitchell CA. The yeast inositol polyphosphate 5-phosphatases inp52p and inp53p translocate to actin patches following hyperosmotic stress: mechanism for regulating phosphatidylinositol 4,5-bisphosphate at plasma membrane invaginations. Molecular and Cellular Biology. 20: 9376-90. PMID 11094088 DOI: 10.1128/Mcb.20.24.9376-9390.2000  0.451
1997 Fourie AM, Hupp TR, Lane DP, Sang BC, Barbosa MS, Sambrook JF, Gething MJ. HSP70 binding sites in the tumor suppressor protein p53. The Journal of Biological Chemistry. 272: 19471-9. PMID 9235949 DOI: 10.1074/jbc.272.31.19471  0.453
1995 Gething MJ, Blond-Elguindi S, Buchner J, Fourie A, Knarr G, Modrow S, Nanu L, Segal M, Sambrook J. Binding sites for Hsp70 molecular chaperones in natural proteins. Cold Spring Harbor Symposia On Quantitative Biology. 60: 417-28. PMID 8824415 DOI: 10.1101/Sqb.1995.060.01.046  0.409
1995 Alizadeh H, Ma D, Berman M, Bellingham D, Comerford SA, Gething MJ, Sambrook JF, Niederkorn JY. Tissue-type plasminogen activator-induced invasion and metastasis of murine melanomas. Current Eye Research. 14: 449-58. PMID 7671626 DOI: 10.3109/02713689509003755  0.422
1994 Shohet RV, Spitzer S, Madison EL, Bassel-Duby R, Gething MJ, Sambrook JF. Inhibitor-resistant tissue-type plasminogen activator: an improved thrombolytic agent in vitro. Thrombosis and Haemostasis. 71: 124-8. PMID 8165630  0.396
1994 Ma D, Comerford S, Bellingham D, Sambrook J, Gething MJ, Alizadeh H, Anand R, Mellon J, Niederkorn JY. Capacity of simian virus 40 T antigen to induce self-tolerance but not immunological privilege in the anterior chamber of the eye. Transplantation. 57: 718-25. PMID 8140635 DOI: 10.1097/00007890-199403150-00014  0.415
1994 Zunino SJ, Simons LF, Sambrook JF, Gething MJ. Interleukin-1 promotes hyperglycemia and insulitis in mice normally resistant to streptozotocin-induced diabetes. The American Journal of Pathology. 145: 661-70. PMID 8080048  0.326
1994 Orth K, Willnow T, Herz J, Gething MJ, Sambrook J. Low density lipoprotein receptor-related protein is necessary for the internalization of both tissue-type plasminogen activator-inhibitor complexes and free tissue-type plasminogen activator. The Journal of Biological Chemistry. 269: 21117-22. PMID 8063731  0.408
1994 Anand R, Ma D, Alizadeh H, Comerford SA, Sambrook JF, Gething MJ, McLean IW, Niederkorn JY. Characterization of intraocular tumors arising in transgenic mice. Investigative Ophthalmology & Visual Science. 35: 3533-9. PMID 8056529  0.354
1994 Fourie AM, Sambrook JF, Gething MJ. Common and divergent peptide binding specificities of hsp70 molecular chaperones. The Journal of Biological Chemistry. 269: 30470-8. PMID 7982963  0.427
1994 Lacey SW, Naim HY, Magness RR, Gething MJ, Sambrook JF. Expression of lactase-phlorizin hydrolase in sheep is regulated at the RNA level. The Biochemical Journal. 302: 929-35. PMID 7945222 DOI: 10.1042/Bj3020929  0.399
1994 Ma D, Alizadeh H, Comerford SA, Gething MJ, Sambrook JF, Anand R, Niederkorn JY. Rejection of intraocular tumors from transgenic mice by tumor-infiltrating lymphocytes. Current Eye Research. 13: 361-9. PMID 7914482 DOI: 10.3109/02713689409167300  0.357
1994 McMillan DR, Gething MJ, Sambrook J. The cellular response to unfolded proteins: intercompartmental signaling. Current Opinion in Biotechnology. 5: 540-5. PMID 7765470 DOI: 10.1016/0958-1669(94)90071-X  0.503
1994 Naim HY, Jacob R, Naim H, Sambrook JF, Gething MJ. The pro region of human intestinal lactase-phlorizin hydrolase. The Journal of Biological Chemistry. 269: 26933-43. PMID 7523415  0.419
1994 Gething M, Blond-Elguindi S, Mori K, Sambrook JF. 5 Structure, Function, and Regulation of the Endoplasmic Reticulum Chaperone, BiP Cold Spring Harbor Monograph Archive. 26: 111-135. DOI: 10.1101/087969427.26.111  0.544
1993 Blond-Elguindi S, Fourie AM, Sambrook JF, Gething MJ. Peptide-dependent stimulation of the ATPase activity of the molecular chaperone BiP is the result of conversion of oligomers to active monomers. The Journal of Biological Chemistry. 268: 12730-5. PMID 8509407  0.398
1993 Kohno K, Normington K, Sambrook J, Gething MJ, Mori K. The promoter region of the yeast KAR2 (BiP) gene contains a regulatory domain that responds to the presence of unfolded proteins in the endoplasmic reticulum. Molecular and Cellular Biology. 13: 877-90. PMID 8423809 DOI: 10.1128/Mcb.13.2.877  0.594
1993 Mori K, Ma W, Gething MJ, Sambrook J. A transmembrane protein with a cdc2+/CDC28-related kinase activity is required for signaling from the ER to the nucleus. Cell. 74: 743-56. PMID 8358794 DOI: 10.1016/0092-8674(93)90521-Q  0.611
1993 Madison EL, Kobe A, Gething MJ, Sambrook JF, Goldsmith EJ. Converting tissue plasminogen activator to a zymogen: a regulatory triad of Asp-His-Ser. Science (New York, N.Y.). 262: 419-21. PMID 8211162 DOI: 10.1126/Science.8211162  0.43
1993 Kittlesen DJ, Brown LR, Braciale VL, Sambrook JP, Gething MJ, Braciale TJ. Presentation of newly synthesized glycoproteins to CD4+ T lymphocytes. An analysis using influenza hemagglutinin transport mutants. The Journal of Experimental Medicine. 177: 1021-30. PMID 8096235 DOI: 10.1084/Jem.177.4.1021  0.498
1993 Blond-Elguindi S, Cwirla SE, Dower WJ, Lipshutz RJ, Sprang SR, Sambrook JF, Gething MJ. Affinity panning of a library of peptides displayed on bacteriophages reveals the binding specificity of BiP. Cell. 75: 717-28. PMID 7902213 DOI: 10.1016/0092-8674(93)90492-9  0.406
1993 Sykes K, Gething MJ, Sambrook J. Proline isomerases function during heat shock. Proceedings of the National Academy of Sciences of the United States of America. 90: 5853-7. PMID 7685914 DOI: 10.1073/Pnas.90.12.5853  0.497
1992 Gething MJ, Sambrook J. Protein folding in the cell. Nature. 355: 33-45. PMID 1731198 DOI: 10.1038/355033A0  0.5
1992 Mori K, Sant A, Kohno K, Normington K, Gething MJ, Sambrook JF. A 22 bp cis-acting element is necessary and sufficient for the induction of the yeast KAR2 (BiP) gene by unfolded proteins. The Embo Journal. 11: 2583-93. PMID 1628622 DOI: 10.1002/J.1460-2075.1992.Tb05323.X  0.596
1992 Bulleid NJ, Bassel-Duby RS, Freedman RB, Sambrook JF, Gething MJ. Cell-free synthesis of enzymically active tissue-type plasminogen activator. Protein folding determines the extent of N-linked glycosylation. The Biochemical Journal. 286: 275-80. PMID 1520279  0.507
1992 Orth K, Madison EL, Gething MJ, Sambrook JF, Herz J. Complexes of tissue-type plasminogen activator and its serpin inhibitor plasminogen-activator inhibitor type 1 are internalized by means of the low density lipoprotein receptor-related protein/alpha 2-macroglobulin receptor. Proceedings of the National Academy of Sciences of the United States of America. 89: 7422-6. PMID 1502153 DOI: 10.1073/Pnas.89.16.7422  0.43
1992 Gallagher PJ, Henneberry JM, Sambrook JF, Gething MJ. Glycosylation requirements for intracellular transport and function of the hemagglutinin of influenza virus. Journal of Virology. 66: 7136-45. PMID 1331514  0.509
1992 Segal MS, Bye JM, Sambrook JF, Gething MJ. Disulfide bond formation during the folding of influenza virus hemagglutinin. The Journal of Cell Biology. 118: 227-44. PMID 1321156 DOI: 10.1083/jcb.118.2.227  0.517
1992 Bassel-Duby R, Jiang NY, Bittick T, Madison E, McGookey D, Orth K, Shohet R, Sambrook J, Gething MJ. Tyrosine 67 in the epidermal growth factor-like domain of tissue-type plasminogen activator is important for clearance by a specific hepatic receptor. The Journal of Biological Chemistry. 267: 9668-77. PMID 1315765  0.464
1991 Naim HY, Lacey SW, Sambrook JF, Gething MJ. Expression of a full-length cDNA coding for human intestinal lactase-phlorizin hydrolase reveals an uncleaved, enzymatically active, and transport-competent protein. The Journal of Biological Chemistry. 266: 12313-20. PMID 1905719  0.504
1990 Beck PJ, Gething MJ, Sambrook J, Lehrman MA. Complementing mutant alleles define three loci involved in mannosylation of Man5-GlcNAc2-P-P-dolichol in Chinese hamster ovary cells. Somatic Cell and Molecular Genetics. 16: 539-48. PMID 2267628 DOI: 10.1007/Bf01233094  0.474
1990 Beck PJ, Orlean P, Albright C, Robbins PW, Gething MJ, Sambrook JF. The Saccharomyces cerevisiae DPM1 gene encoding dolichol-phosphate-mannose synthase is able to complement a glycosylation-defective mammalian cell line. Molecular and Cellular Biology. 10: 4612-22. PMID 2201896 DOI: 10.1128/Mcb.10.9.4612  0.495
1990 Bird P, Gething MJ, Sambrook J. The functional efficiency of a mammalian signal peptide is directly related to its hydrophobicity. The Journal of Biological Chemistry. 265: 8420-5. PMID 2187865  0.439
1990 Roman LM, Simons LF, Hammer RE, Sambrook JF, Gething MJ. The expression of influenza virus hemagglutinin in the pancreatic beta cells of transgenic mice results in autoimmune diabetes. Cell. 61: 383-96. PMID 2185889 DOI: 10.1016/0092-8674(90)90521-F  0.41
1990 Madison EL, Goldsmith EJ, Gething MJ, Sambrook JF, Gerard RD. Restoration of serine protease-inhibitor interaction by protein engineering. The Journal of Biological Chemistry. 265: 21423-6. PMID 2123870  0.453
1990 Madison EL, Goldsmith EJ, Gerard RD, Gething MJ, Sambrook JF, Bassel-Duby RS. Amino acid residues that affect interaction of tissue-type plasminogen activator with plasminogen activator inhibitor 1. Proceedings of the National Academy of Sciences of the United States of America. 87: 3530-3. PMID 2110366 DOI: 10.1073/Pnas.87.9.3530  0.459
1990 Gething MJ, Sambrook J. Transport and assembly processes in the endoplasmic reticulum. Seminars in Cell Biology. 1: 65-72. PMID 1983272  0.479
1989 Gething MJ, McCammon K, Sambrook J. Protein folding and intracellular transport: evaluation of conformational changes in nascent exocytotic proteins. Methods in Cell Biology. 32: 185-206. PMID 2691850 DOI: 10.1016/S0091-679X(08)61171-1  0.468
1989 Normington K, Kohno K, Kozutsumi Y, Gething MJ, Sambrook J. S. cerevisiae encodes an essential protein homologous in sequence and function to mammalian BiP. Cell. 57: 1223-36. PMID 2661019 DOI: 10.1016/0092-8674(89)90059-7  0.508
1989 Hearing J, Gething MJ, Sambrook J. Addition of truncated oligosaccharides to influenza virus hemagglutinin results in its temperature-conditional cell-surface expression. The Journal of Cell Biology. 108: 355-65. PMID 2645296 DOI: 10.1083/Jcb.108.2.355  0.483
1989 Gething MJ, Sambrook J. Protein folding and intracellular transport: studies on influenza virus haemagglutinin. Biochemical Society Symposium. 55: 155-66. PMID 2619766  0.497
1989 Sambrook J, Gething MJ. Protein structure. Chaperones, paperones. Nature. 342: 224-5. PMID 2572969 DOI: 10.1038/342224a0  0.427
1989 Kozutsumi Y, Normington K, Press E, Slaughter C, Sambrook J, Gething MJ. Identification of immunoglobulin heavy chain binding protein as glucose-regulated protein 78 on the basis of amino acid sequence, immunological cross-reactivity, and functional activity. Journal of Cell Science. Supplement. 11: 115-37. PMID 2559088 DOI: 10.1242/Jcs.1989.Supplement_11.10  0.514
1989 Hearing J, Hunter E, Rodgers L, Gething MJ, Sambrook J. Isolation of Chinese hamster ovary cell lines temperature conditional for the cell-surface expression of integral membrane glycoproteins. The Journal of Cell Biology. 108: 339-53. PMID 2537314 DOI: 10.1083/Jcb.108.2.339  0.506
1989 Madison EL, Goldsmith EJ, Gerard RD, Gething MJ, Sambrook JF. Serpin-resistant mutants of human tissue-type plasminogen activator. Nature. 339: 721-4. PMID 2500599 DOI: 10.1038/339721A0  0.445
1989 Boose JA, Kuismanen E, Gerard R, Sambrook J, Gething MJ. The single-chain form of tissue-type plasminogen activator has catalytic activity: studies with a mutant enzyme that lacks the cleavage site. Biochemistry. 28: 635-43. PMID 2496749 DOI: 10.1021/Bi00428A033  0.442
1989 Gething MJ, Mccammon K, Sambrook J. Chapter 7 Protein Folding and Intracellular Transport: Evaluation of Conformational Changes in Nascent Exocytotic Proteins Methods in Cell Biology. 32: 185-206. DOI: 10.1016/S0091-679X(08)61171-1  0.447
1989 Madison E, Goldsmith E, Gerard R, Gething M, Sambrook J. Mutants of human time-type plasminogen activator that are resistant to inhibition by the serpin PAI-1 Fibrinolysis. 3: 18. DOI: 10.1016/0268-9499(89)90117-3  0.469
1989 Madison E, Gething M, Sambrook J. The use of “loop-switch” mutations to probe fine structure(function relationships in the kringle II domain of t-PA Fibrinolysis. 3: 18. DOI: 10.1016/0268-9499(89)90116-1  0.468
1988 Kozutsumi Y, Segal M, Normington K, Gething MJ, Sambrook J. The presence of malfolded proteins in the endoplasmic reticulum signals the induction of glucose-regulated proteins. Nature. 332: 462-4. PMID 3352747 DOI: 10.1038/332462A0  0.518
1988 Gething MJ, Adler B, Boose JA, Gerard RD, Madison EL, McGookey D, Meidell RS, Roman LM, Sambrook J. Variants of human tissue-type plasminogen activator that lack specific structural domains of the heavy chain. The Embo Journal. 7: 2731-40. PMID 2846282 DOI: 10.1002/J.1460-2075.1988.Tb03127.X  0.51
1988 Gallagher P, Henneberry J, Wilson I, Sambrook J, Gething MJ. Addition of carbohydrate side chains at novel sites on influenza virus hemagglutinin can modulate the folding, transport, and activity of the molecule. The Journal of Cell Biology. 107: 2059-73. PMID 2461945 DOI: 10.1083/Jcb.107.6.2059  0.534
1988 Gething MJ, Henneberry J, Sambrook J. Chapter 11 Fusion Activity of the Hemagglutinin of Influenza Virus Current Topics in Membranes and Transport. 32: 337-364. DOI: 10.1016/S0070-2161(08)60139-2  0.499
1987 Chao CC, Bird P, Gething MJ, Sambrook J. Posttranslational translocation of influenza virus hemagglutinin across microsomal membranes. Molecular and Cellular Biology. 7: 3842-5. PMID 3683400 DOI: 10.1128/MCB.7.10.3842  0.527
1987 Bird P, Gething MJ, Sambrook J. Translocation in yeast and mammalian cells: not all signal sequences are functionally equivalent. The Journal of Cell Biology. 105: 2905-14. PMID 3320059  0.484
1987 Braciale TJ, Morrison LA, Sweetser MT, Sambrook J, Gething MJ, Braciale VL. Antigen presentation pathways to class I and class II MHC-restricted T lymphocytes. Immunological Reviews. 98: 95-114. PMID 2443444 DOI: 10.1111/J.1600-065X.1987.Tb00521.X  0.324
1987 Braciale TJ, Braciale VL, Winkler M, Stroynowski I, Hood L, Sambrook J, Gething MJ. On the role of the transmembrane anchor sequence of influenza hemagglutinin in target cell recognition by class I MHC-restricted, hemagglutinin-specific cytolytic T lymphocytes. The Journal of Experimental Medicine. 166: 678-92. PMID 2442285  0.528
1986 Doyle C, Sambrook J, Gething MJ. Analysis of progressive deletions of the transmembrane and cytoplasmic domains of influenza hemagglutinin. The Journal of Cell Biology. 103: 1193-204. PMID 3771631 DOI: 10.1083/Jcb.103.4.1193  0.744
1986 Gething MJ, McCammon K, Sambrook J. Expression of wild-type and mutant forms of influenza hemagglutinin: the role of folding in intracellular transport. Cell. 46: 939-50. PMID 3757030 DOI: 10.1016/0092-8674(86)90076-0  0.554
1986 Gething MJ, Doms RW, York D, White J. Studies on the mechanism of membrane fusion: site-specific mutagenesis of the hemagglutinin of influenza virus. The Journal of Cell Biology. 102: 11-23. PMID 3753607 DOI: 10.1083/Jcb.102.1.11  0.36
1986 Sambrook J, Hanahan D, Rodgers L, Gething MJ. Expression of human tissue-type plasminogen activator from lytic viral vectors and in established cell lines. Molecular Biology & Medicine. 3: 459-81. PMID 3039288  0.481
1986 Roth MG, Doyle C, Sambrook J, Gething MJ. Heterologous transmembrane and cytoplasmic domains direct functional chimeric influenza virus hemagglutinins into the endocytic pathway. The Journal of Cell Biology. 102: 1271-83. PMID 3007532 DOI: 10.1083/Jcb.102.4.1271  0.748
1985 Doyle C, Roth MG, Sambrook J, Gething MJ. Mutations in the cytoplasmic domain of the influenza virus hemagglutinin affect different stages of intracellular transport. The Journal of Cell Biology. 100: 704-14. PMID 3972890 DOI: 10.1083/Jcb.100.3.704  0.746
1985 Sharma S, Rodgers L, Brandsma J, Gething MJ, Sambrook J. SV40 T antigen and the exocytotic pathway. The Embo Journal. 4: 1479-89. PMID 3849428 DOI: 10.1002/J.1460-2075.1985.Tb03806.X  0.49
1985 Sambrook J, Rodgers L, White J, Gething MJ. Lines of BPV-transformed murine cells that constitutively express influenza virus hemagglutinin. The Embo Journal. 4: 91-103. PMID 2990897 DOI: 10.1002/J.1460-2075.1985.Tb02322.X  0.509
1985 Gething MJ, Doyle C, Roth M, Sambrook J. Chapter 2 Mutational Analysis of the Structure and Function of the Influenza Virus Hemagglutinin Current Topics in Membranes and Transport. 23: 17-41. DOI: 10.1016/S0070-2161(08)60148-3  0.755
1984 Braciale TJ, Braciale VL, Henkel TJ, Sambrook J, Gething MJ. Cytotoxic T lymphocyte recognition of the influenza hemagglutinin gene product expressed by DNA-mediated gene transfer. The Journal of Experimental Medicine. 159: 341-54. PMID 6198429  0.473
1983 Roth MG, Compans RW, Giusti L, Davis AR, Nayak DP, Gething MJ, Sambrook J. Influenza virus hemagglutinin expression is polarized in cells infected with recombinant SV40 viruses carrying cloned hemagglutinin DNA. Cell. 33: 435-43. PMID 6305510 DOI: 10.1016/0092-8674(83)90425-7  0.503
1982 Gething MJ, Sambrook J. Construction of influenza haemagglutinin genes that code for intracellular and secreted forms of the protein. Nature. 300: 598-603. PMID 7144911 DOI: 10.1038/300598A0  0.598
1982 White J, Helenius A, Gething MJ. Haemagglutinin of influenza virus expressed from a cloned gene promotes membrane fusion. Nature. 300: 658-9. PMID 6815542 DOI: 10.1038/300658A0  0.31
1981 Gething MJ, Sambrook J. Cell-surface expression of influenza haemagglutinin from a cloned DNA copy of the RNA gene. Nature. 293: 620-5. PMID 6270568 DOI: 10.1038/293620A0  0.491
1980 Koszinowski UH, Allen H, Gething MJ, Waterfield MD, Klenk HD. Recognition of viral glycoproteins by influenza A-specific cross-reactive cytolytic T lymphocytes. The Journal of Experimental Medicine. 151: 945-58. PMID 6154763 DOI: 10.1084/Jem.151.4.945  0.32
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