| Year |
Citation |
Score |
| 2020 |
Liu W, Yin Y, Wang M, Fan T, Zhu Y, Shen L, Peng S, Gao J, Deng G, Meng X, Kong L, Feng GS, Guo W, Xu Q, Sun Y. Disrupting phosphatase SHP2 in macrophages protects mice from high-fat diet-induced hepatic steatosis and insulin resistance by elevating IL-18 levels. The Journal of Biological Chemistry. PMID 32546483 DOI: 10.1074/Jbc.Ra119.011840 |
0.328 |
|
| 2019 |
Yang BH, Wang K, Wan S, Liang Y, Yuan X, Dong Y, Cho S, Xu W, Jepsen K, Feng GS, Lu LF, Xue HH, Fu W. TCF1 and LEF1 Control Treg Competitive Survival and Tfr Development to Prevent Autoimmune Diseases. Cell Reports. 27: 3629-3645.e6. PMID 31216480 DOI: 10.1016/J.Celrep.2019.05.061 |
0.35 |
|
| 2019 |
Li Y, Liu WS, Yi J, Kong SB, Ding JC, Zhao YN, Tian YP, Feng GS, Li CJ, Liu W, Wang HB, Lu ZX. The role of tyrosine phosphatase Shp2 in spermatogonial differentiation and spermatocyte meiosis. Asian Journal of Andrology. PMID 31210146 DOI: 10.4103/Aja.Aja_49_19 |
0.426 |
|
| 2019 |
Huo Y, Chen WS, Lee J, Feng GS, Newton IG. Stress Conditions Induced by Locoregional Therapies Stimulate Enrichment and Proliferation of Liver Cancer Stem Cells. Journal of Vascular and Interventional Radiology : Jvir. PMID 31208945 DOI: 10.1016/J.Jvir.2019.02.026 |
0.306 |
|
| 2019 |
Li H, Mao Y, Bouaziz M, Yu H, Qu X, Wang F, Feng GS, Shawber C, Zhang X. Lens differentiation is controlled by the balance between PDGF and FGF signaling. Plos Biology. 17: e3000133. PMID 30716082 DOI: 10.1371/Journal.Pbio.3000133 |
0.494 |
|
| 2018 |
Liu JJ, Li Y, Chen WS, Liang Y, Wang G, Zong M, Kaneko K, Xu R, Karin M, Feng GS. Shp2 Deletion in Hepatocytes Suppresses Hepatocarcinogenesis Driven by Oncogenic β-Catenin, PIK3CA and MET. Journal of Hepatology. PMID 29505847 DOI: 10.1016/J.Jhep.2018.02.014 |
0.358 |
|
| 2018 |
Collins TN, Mao Y, Li H, Bouaziz M, Hong A, Feng GS, Wang F, Quilliam LA, Chen L, Park T, Curran T, Zhang X. Crk proteins transduce FGF signaling to promote lens fiber cell elongation. Elife. 7. PMID 29360039 DOI: 10.7554/Elife.32586 |
0.409 |
|
| 2017 |
Liang Y, Feng Y, Zong M, Wei X, Lee J, Feng Y, Li H, Yang G, Wu ZJ, Fu XD, Feng GS. β-Catenin Deficiency in Hepatocytes Aggravates Hepatocarcinogenesis Driven by Oncogenic β-Catenin and MET. Hepatology (Baltimore, Md.). PMID 29152756 DOI: 10.1002/Hep.29661 |
0.346 |
|
| 2017 |
Lee J, Liao R, Wang G, Yang BH, Luo X, Varki NM, Qiu SJ, Ren B, Fu W, Feng GS. Preventive Inhibition of Liver Tumorigenesis by Systemic Activation of Innate Immune Functions. Cell Reports. 21: 1870-1882. PMID 29141219 DOI: 10.1016/J.Celrep.2017.10.064 |
0.323 |
|
| 2017 |
Garg A, Bansal M, Gotoh N, Feng GS, Zhong J, Wang F, Kariminejad A, Brooks S, Zhang X. Alx4 relays sequential FGF signaling to induce lacrimal gland morphogenesis. Plos Genetics. 13: e1007047. PMID 29028795 DOI: 10.1371/Journal.Pgen.1007047 |
0.408 |
|
| 2017 |
Cheng J, Zhong Y, Chen S, Sun Y, Huang L, Kang Y, Chen B, Chen G, Wang F, Tian Y, Liu W, Feng GS, Lu Z. Gab2 mediates hepatocellular carcinogenesis by integrating multiple signaling pathways. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. PMID 28842424 DOI: 10.1096/Fj.201700120Rr |
0.466 |
|
| 2017 |
Ran H, Kong S, Zhang S, Cheng J, Zhou C, He B, Xin Q, Lydon JP, DeMayo FJ, Feng GS, Xia G, Lu Z, Wang C, Wang H. Nuclear Shp2 directs normal embryo implantation via facilitating the ERα tyrosine phosphorylation by the Src kinase. Proceedings of the National Academy of Sciences of the United States of America. PMID 28424251 DOI: 10.1073/Pnas.1700978114 |
0.421 |
|
| 2016 |
Luo X, Liao R, Hanley KL, Zhu HH, Malo KN, Hernandez C, Wei X, Varki NM, Alderson N, Chu C, Li S, Fan J, Loomba R, Qiu SJ, Feng GS. Dual Shp2 and Pten Deficiencies Promote Non-alcoholic Steatohepatitis and Genesis of Liver Tumor-Initiating Cells. Cell Reports. 17: 2979-2993. PMID 27974211 DOI: 10.1016/J.Celrep.2016.11.048 |
0.484 |
|
| 2016 |
Liu W, Guo W, Shen L, Chen Z, Luo Q, Luo X, Feng GS, Shu Y, Gu Y, Xu Q, Sun Y. T lymphocyte SHP2-deficiency triggers anti-tumor immunity to inhibit colitis-associated cancer in mice. Oncotarget. PMID 27935860 DOI: 10.18632/Oncotarget.13812 |
0.36 |
|
| 2016 |
Mathew G, Hannan A, Hertzler-Schaefer K, Wang F, Feng GS, Zhong J, Zhao JJ, Downward J, Zhang X. Targeting of Ras-mediated FGF signaling suppresses Pten-deficient skin tumor. Proceedings of the National Academy of Sciences of the United States of America. PMID 27799550 DOI: 10.1073/Pnas.1604450113 |
0.374 |
|
| 2016 |
Chen S, Kang Y, Sun Y, Zhong Y, Li Y, Deng L, Tao J, Li Y, Tian Y, Zhao Y, Cheng J, Liu W, Feng GS, Lu Z. Deletion of Gab2 in mice protects against hepatic steatosis and steatohepatitis: a novel therapeutic target for fatty liver disease. Journal of Molecular Cell Biology. PMID 27282405 DOI: 10.1093/Jmcb/Mjw028 |
0.339 |
|
| 2016 |
Coulombe G, Langlois A, De Palma G, Langlois MJ, McCarville JL, Gagné-Sanfaçon J, Perreault N, Feng GS, Bercik P, Boudreau F, Verdu EF, Rivard N. SHP-2 Phosphatase Prevents Colonic Inflammation by Controlling Secretory Cell Differentiation and Maintaining Host-Microbiota Homeostasis. Journal of Cellular Physiology. PMID 27100271 DOI: 10.1002/Jcp.25407 |
0.371 |
|
| 2016 |
Ma X, Qu X, Zhu W, Li YS, Yuan S, Zhang H, Liu J, Wang P, Lai CS, Zanella F, Feng GS, Sheikh F, Chien S, Chen S. Deterministically patterned biomimetic human iPSC-derived hepatic model via rapid 3D bioprinting. Proceedings of the National Academy of Sciences of the United States of America. PMID 26858399 DOI: 10.1073/Pnas.1524510113 |
0.311 |
|
| 2016 |
Chen WS, Zhu HH, Feng GS. Treating Leukemia at Risk of Inducing Severe Anemia. Experimental Hematology. PMID 26826310 DOI: 10.1016/J.Exphem.2016.01.004 |
0.528 |
|
| 2015 |
Zhu HH, Luo X, Zhang K, Cui J, Zhao H, Ji Z, Zhou Z, Yao J, Zeng L, Ji K, Gao WQ, Zhang ZY, Feng GS. Shp2 and Pten have antagonistic roles in myeloproliferation but cooperate to promote erythropoiesis in mammals. Proceedings of the National Academy of Sciences of the United States of America. PMID 26460004 DOI: 10.1073/pnas.1507599112 |
0.506 |
|
| 2015 |
Hu X, Tang Z, Li Y, Liu W, Zhang S, Wang B, Tian Y, Zhao Y, Ran H, Liu W, Feng GS, Shuai J, Wang H, Lu Z. Deletion of the tyrosine phosphatase Shp2 in Sertoli cells causes infertility in mice. Scientific Reports. 5: 12982. PMID 26265072 DOI: 10.1038/Srep12982 |
0.438 |
|
| 2015 |
Deng Z, Ma S, Zhou H, Zang A, Fang Y, Li T, Shi H, Liu M, Du M, Taylor PR, Zhu HH, Chen J, Meng G, Li F, Chen C, ... ... Feng GS, et al. Tyrosine phosphatase SHP-2 mediates C-type lectin receptor-induced activation of the kinase Syk and anti-fungal TH17 responses. Nature Immunology. 16: 642-52. PMID 25915733 DOI: 10.1038/Ni.3155 |
0.446 |
|
| 2015 |
Luo T, Fu J, Xu A, Su B, Ren Y, Li N, Zhu J, Zhao X, Dai R, Cao J, Wang B, Qin W, Jiang J, Li J, Wu M, ... Feng G, et al. PSMD10/Gankyrin Induces Autophagy to Promote Tumor Progression through Cytoplasmic Interaction with ATG7 and Nuclear Transactivation of ATG7 Expression. Autophagy. 0. PMID 25905985 DOI: 10.1080/15548627.2015.1034405 |
0.331 |
|
| 2015 |
Han T, Xiang DM, Sun W, Liu N, Sun HL, Wen W, Shen WF, Wang RY, Chen C, Wang X, Cheng Z, Li HY, Wu MC, Cong WM, Feng GS, et al. PTPN11/Shp2 Overexpression Enhances Liver Cancer Progression and Predicts Poor Prognosis of Patients. Journal of Hepatology. PMID 25865556 DOI: 10.1016/J.Jhep.2015.03.036 |
0.386 |
|
| 2015 |
Li XJ, Goodwin CB, Nabinger SC, Richine BM, Yang Z, Hanenberg H, Ohnishi H, Matozaki T, Feng GS, Chan RJ. Protein-tyrosine phosphatase Shp2 positively regulates macrophage oxidative burst. The Journal of Biological Chemistry. 290: 3894-909. PMID 25538234 DOI: 10.1074/Jbc.M114.614057 |
0.638 |
|
| 2015 |
Li S, Ni A, Feng GS. Bridging cell surface receptor with nuclear receptors in control of bile acid homeostasis. Acta Pharmacologica Sinica. 36: 113-8. PMID 25500873 DOI: 10.1038/Aps.2014.118 |
0.354 |
|
| 2015 |
Su B, Luo T, Zhu J, Fu J, Zhao X, Chen L, Zhang H, Ren Y, Yu L, Yang X, Wu M, Feng G, Li S, Chen Y, Wang H. Interleukin-1β/Iinterleukin-1 receptor-associated kinase 1 inflammatory signaling contributes to persistent Gankyrin activation during hepatocarcinogenesis. Hepatology (Baltimore, Md.). 61: 585-97. PMID 25294684 DOI: 10.1002/Hep.27551 |
0.389 |
|
| 2014 |
Li J, Kang Y, Wei L, Liu W, Tian Y, Chen B, Lin X, Li Y, Feng GS, Lu Z. Tyrosine phosphatase Shp2 mediates the estrogen biological action in breast cancer via interaction with the estrogen extranuclear receptor. Plos One. 9: e102847. PMID 25048202 DOI: 10.1371/Journal.Pone.0102847 |
0.347 |
|
| 2014 |
Li S, Hsu DD, Li B, Luo X, Alderson N, Qiao L, Ma L, Zhu HH, He Z, Suino-Powell K, Ji K, Li J, Shao J, Xu HE, Li T, ... Feng GS, et al. Cytoplasmic tyrosine phosphatase Shp2 coordinates hepatic regulation of bile acid and FGF15/19 signaling to repress bile acid synthesis. Cell Metabolism. 20: 320-32. PMID 24981838 DOI: 10.1016/J.Cmet.2014.05.020 |
0.532 |
|
| 2014 |
Lee B, Qiao L, Lu M, Yoo HS, Cheung W, Mak R, Schaack J, Feng GS, Chi NW, Olefsky JM, Shao J. C/EBPα regulates macrophage activation and systemic metabolism. American Journal of Physiology. Endocrinology and Metabolism. 306: E1144-54. PMID 24691027 DOI: 10.1152/Ajpendo.00002.2014 |
0.303 |
|
| 2014 |
Li H, Tao C, Cai Z, Hertzler-Schaefer K, Collins TN, Wang F, Feng GS, Gotoh N, Zhang X. Frs2α and Shp2 signal independently of Gab to mediate FGF signaling in lens development. Journal of Cell Science. 127: 571-82. PMID 24284065 DOI: 10.1242/Jcs.134478 |
0.408 |
|
| 2014 |
Puri P, Phillips BT, Suzuki H, Orwig KE, Rajkovic A, Lapinski PE, King PD, Feng GS, Walker WH. The transition from stem cell to progenitor spermatogonia and male fertility requires the SHP2 protein tyrosine phosphatase. Stem Cells (Dayton, Ohio). 32: 741-53. PMID 24123360 DOI: 10.1002/Stem.1572 |
0.343 |
|
| 2014 |
Li X, Goodwin C, Yang Z, Nabinger SC, Richine B, Chan G, Hanenberg H, Ohnishi H, Matozaki T, El Benna J, Feng G, Neel B, Chan RJ. Macrophage NADPH Oxidase Activation and ROS Production Is Positively Regulated By Shp2 Phosphatase Function Blood. 124: 1397-1397. DOI: 10.1182/Blood.V124.21.1397.1397 |
0.636 |
|
| 2013 |
Ng GY, Yeh LK, Zhang Y, Liu H, Feng GS, Kao WW, Liu CY. Role of SH2-containing tyrosine phosphatase Shp2 in mouse corneal epithelial stratification. Investigative Ophthalmology & Visual Science. 54: 7933-42. PMID 24204042 DOI: 10.1167/Iovs.13-12646 |
0.391 |
|
| 2013 |
Zheng L, Yang W, Wu F, Wang C, Yu L, Tang L, Qiu B, Li Y, Guo L, Wu M, Feng G, Zou D, Wang H. Prognostic significance of AMPK activation and therapeutic effects of metformin in hepatocellular carcinoma. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 19: 5372-80. PMID 23942093 DOI: 10.1158/1078-0432.Ccr-13-0203 |
0.367 |
|
| 2013 |
Wen W, Han T, Chen C, Huang L, Sun W, Wang X, Chen SZ, Xiang DM, Tang L, Cao D, Feng GS, Wu MC, Ding J, Wang HY. Cyclin G1 expands liver tumor-initiating cells by Sox2 induction via Akt/mTOR signaling. Molecular Cancer Therapeutics. 12: 1796-804. PMID 23804702 DOI: 10.1158/1535-7163.Mct-13-0099 |
0.355 |
|
| 2013 |
Cai Z, Tao C, Li H, Ladher R, Gotoh N, Feng GS, Wang F, Zhang X. Deficient FGF signaling causes optic nerve dysgenesis and ocular coloboma. Development (Cambridge, England). 140: 2711-23. PMID 23720040 DOI: 10.1242/Dev.089987 |
0.347 |
|
| 2013 |
Coulombe G, Leblanc C, Cagnol S, Maloum F, Lemieux E, Perreault N, Feng GS, Boudreau F, Rivard N. Epithelial tyrosine phosphatase SHP-2 protects against intestinal inflammation in mice. Molecular and Cellular Biology. 33: 2275-84. PMID 23530062 DOI: 10.1128/Mcb.00043-13 |
0.336 |
|
| 2013 |
Chen H, Luo Z, Dong L, Tan Y, Yang J, Feng G, Wu M, Li Z, Wang H. CD133/Prominin-1-Mediated Autophagy and Glucose Uptake Beneficial for Hepatoma Cell Survival Plos One. 8. PMID 23437259 DOI: 10.1371/Journal.Pone.0056878 |
0.318 |
|
| 2013 |
Shi ZQ, Sunico CR, McKercher SR, Cui J, Feng GS, Nakamura T, Lipton SA. S-nitrosylated SHP-2 contributes to NMDA receptor-mediated excitotoxicity in acute ischemic stroke. Proceedings of the National Academy of Sciences of the United States of America. 110: 3137-42. PMID 23382182 DOI: 10.1073/Pnas.1215501110 |
0.313 |
|
| 2013 |
Yu J, Deng R, Zhu HH, Zhang SS, Zhu C, Montminy M, Davis R, Feng GS. Modulation of fatty acid synthase degradation by concerted action of p38 MAP kinase, E3 ligase COP1, and SH2-tyrosine phosphatase Shp2. The Journal of Biological Chemistry. 288: 3823-30. PMID 23269672 DOI: 10.1074/Jbc.M112.397885 |
0.542 |
|
| 2013 |
He Z, Zhu HH, Bauler TJ, Wang J, Ciaraldi T, Alderson N, Li S, Raquil MA, Ji K, Wang S, Shao J, Henry RR, King PD, Feng GS. Nonreceptor tyrosine phosphatase Shp2 promotes adipogenesis through inhibition of p38 MAP kinase. Proceedings of the National Academy of Sciences of the United States of America. 110: E79-88. PMID 23236157 DOI: 10.1073/pnas.1213000110 |
0.44 |
|
| 2013 |
Nabinger SC, Li XJ, Ramdas B, He Y, Zhang X, Zeng L, Richine B, Bowling JD, Fukuda S, Goenka S, Liu Z, Feng GS, Yu M, Sandusky GE, Boswell HS, et al. The protein tyrosine phosphatase, Shp2, positively contributes to FLT3-ITD-induced hematopoietic progenitor hyperproliferation and malignant disease in vivo. Leukemia. 27: 398-408. PMID 23103841 DOI: 10.1038/leu.2012.308 |
0.608 |
|
| 2013 |
Broxmeyer HE, Etienne-Julan M, Gotoh A, Braun SE, Lu L, Cooper S, Feng GS, Li XJ, Chan RJ. Hematopoietic colony formation from human growth factor-dependent TF1 cells and human cord blood myeloid progenitor cells depends on SHP2 phosphatase function. Stem Cells and Development. 22: 998-1006. PMID 23082805 DOI: 10.1089/Scd.2012.0478 |
0.573 |
|
| 2012 |
Haglund E, Sułkowska JI, He Z, Feng GS, Jennings PA, Onuchic JN. The unique cysteine knot regulates the pleotropic hormone leptin. Plos One. 7: e45654. PMID 23029163 DOI: 10.1371/Journal.Pone.0045654 |
0.339 |
|
| 2012 |
Wu K, Ding J, Chen C, Sun W, Ning BF, Wen W, Huang L, Han T, Yang W, Wang C, Li Z, Wu MC, Feng GS, Xie WF, Wang HY. Hepatic transforming growth factor beta gives rise to tumor-initiating cells and promotes liver cancer development. Hepatology (Baltimore, Md.). 56: 2255-67. PMID 22898879 DOI: 10.1002/Hep.26007 |
0.363 |
|
| 2012 |
Li S, Hsu DD, Wang H, Feng GS. Dual faces of SH2-containing protein-tyrosine phosphatase Shp2/PTPN11 in tumorigenesis. Frontiers of Medicine. 6: 275-9. PMID 22869052 DOI: 10.1007/S11684-012-0216-4 |
0.356 |
|
| 2012 |
Mali RS, Ma P, Zeng LF, Martin H, Ramdas B, He Y, Sims E, Nabinger S, Ghosh J, Sharma N, Munugalavadla V, Chatterjee A, Li S, Sandusky G, Craig AW, ... ... Feng GS, et al. Role of SHP2 phosphatase in KIT-induced transformation: identification of SHP2 as a druggable target in diseases involving oncogenic KIT. Blood. 120: 2669-78. PMID 22806893 DOI: 10.1182/Blood-2011-08-375873 |
0.595 |
|
| 2012 |
Huang H, Woo AJ, Waldon Z, Schindler Y, Moran TB, Zhu HH, Feng GS, Steen H, Cantor AB. A Src family kinase-Shp2 axis controls RUNX1 activity in megakaryocyte and T-lymphocyte differentiation. Genes & Development. 26: 1587-601. PMID 22759635 DOI: 10.1101/Gad.192054.112 |
0.576 |
|
| 2012 |
Huang J, Yan J, Zhang J, Zhu S, Wang Y, Shi T, Zhu C, Chen C, Liu X, Cheng J, Mustelin T, Feng GS, Chen G, Yu J. SUMO1 modification of PTEN regulates tumorigenesis by controlling its association with the plasma membrane. Nature Communications. 3: 911. PMID 22713753 DOI: 10.1038/Ncomms1919 |
0.349 |
|
| 2012 |
Yang W, Wang C, Lin Y, Liu Q, Yu LX, Tang L, Yan HX, Fu J, Chen Y, Zhang HL, Tang L, Zheng LY, He YQ, Li YQ, Wu FQ, ... ... Feng GS, et al. OV6⁺ tumor-initiating cells contribute to tumor progression and invasion in human hepatocellular carcinoma. Journal of Hepatology. 57: 613-20. PMID 22612999 DOI: 10.1016/J.Jhep.2012.04.024 |
0.319 |
|
| 2012 |
Sharma N, Kumar V, Everingham S, Mali RS, Kapur R, Zeng LF, Zhang ZY, Feng GS, Hartmann K, Roers A, Craig AW. SH2 domain-containing phosphatase 2 is a critical regulator of connective tissue mast cell survival and homeostasis in mice. Molecular and Cellular Biology. 32: 2653-63. PMID 22566685 DOI: 10.1128/Mcb.00308-12 |
0.365 |
|
| 2012 |
He Z, Zhang SS, Meng Q, Li S, Zhu HH, Raquil MA, Alderson N, Zhang H, Wu J, Rui L, Cai D, Feng GS. Shp2 controls female body weight and energy balance by integrating leptin and estrogen signals. Molecular and Cellular Biology. 32: 1867-78. PMID 22431513 DOI: 10.1128/Mcb.06712-11 |
0.413 |
|
| 2012 |
Qian YW, Chen Y, Yang W, Fu J, Cao J, Ren YB, Zhu JJ, Su B, Luo T, Zhao XF, Dai RY, Li JJ, Sun W, Wu MC, Feng GS, et al. p28(GANK) prevents degradation of Oct4 and promotes expansion of tumor-initiating cells in hepatocarcinogenesis. Gastroenterology. 142: 1547-58.e14. PMID 22387393 DOI: 10.1053/J.Gastro.2012.02.042 |
0.318 |
|
| 2012 |
Zhang X, Zhang Y, Tao B, Teng L, Li Y, Cao R, Gui Q, Ye M, Mou X, Cheng H, Hu H, Zhou R, Wu X, Xie Q, Ning W, ... ... Feng GS, et al. Loss of Shp2 in alveoli epithelia induces deregulated surfactant homeostasis, resulting in spontaneous pulmonary fibrosis. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 26: 2338-50. PMID 22362894 DOI: 10.1096/Fj.11-200139 |
0.53 |
|
| 2012 |
Wen W, Ding J, Sun W, Fu J, Chen Y, Wu K, Ning B, Han T, Huang L, Chen C, Xie D, Li Z, Feng G, Wu M, Xie W, et al. Cyclin G1-mediated epithelial-mesenchymal transition via phosphoinositide 3-kinase/Akt signaling facilitates liver cancer progression Hepatology. 55: 1787-1798. PMID 22271581 DOI: 10.1002/Hep.25596 |
0.342 |
|
| 2012 |
Nabinger SC, Li XJ, Ramdas B, He Y, Zhang X, Richine B, Bowling J, Fukuda S, Goenka S, Liu Z, Feng G, Yu M, Sandusky G, Boswell HS, Zhang Z, et al. The Protein Tyrosine Phosphatase, Shp2, Positively Contributes to FLT3-ITD-Induced Malignant Disease in Vivo and Co-Localizes with Nuclear Phospho-STAT5 in FLT3-ITD-Expressing Leukemic Cells. Blood. 120: 2420-2420. DOI: 10.1182/Blood.V120.21.2420.2420 |
0.643 |
|
| 2011 |
Li L, Chen L, Hu L, Liu Y, Sun HY, Tang J, Hou YJ, Chang YX, Tu QQ, Feng GS, Shen F, Wu MC, Wang HY. Nuclear factor high-mobility group box1 mediating the activation of Toll-like receptor 4 signaling in hepatocytes in the early stage of nonalcoholic fatty liver disease in mice. Hepatology (Baltimore, Md.). 54: 1620-30. PMID 21809356 DOI: 10.1002/Hep.24552 |
0.392 |
|
| 2011 |
Sun W, Ding J, Wu K, Ning BF, Wen W, Sun HY, Han T, Huang L, Dong LW, Yang W, Deng X, Li Z, Wu MC, Feng GS, Xie WF, et al. Gankyrin-mediated dedifferentiation facilitates the tumorigenicity of rat hepatocytes and hepatoma cells. Hepatology (Baltimore, Md.). 54: 1259-72. PMID 21735473 DOI: 10.1002/Hep.24530 |
0.385 |
|
| 2011 |
Zhu HH, Feng GS. The dynamic interplay between a PTK (Kit) and a PTP (Shp2) in hematopoietic stem and progenitor cells. Cell Cycle (Georgetown, Tex.). 10: 2241-2. PMID 21701261 DOI: 10.4161/Cc.10.14.15861 |
0.389 |
|
| 2011 |
Futami M, Zhu QS, Whichard ZL, Xia L, Ke Y, Neel BG, Feng GS, Corey SJ. G-CSF receptor activation of the Src kinase Lyn is mediated by Gab2 recruitment of the Shp2 phosphatase. Blood. 118: 1077-86. PMID 21636860 DOI: 10.1182/Blood-2009-12-261636 |
0.533 |
|
| 2011 |
Cai Z, Simons DL, Fu XY, Feng GS, Wu SM, Zhang X. Loss of Shp2-mediated mitogen-activated protein kinase signaling in Muller glial cells results in retinal degeneration. Molecular and Cellular Biology. 31: 2973-83. PMID 21576358 DOI: 10.1128/MCB.05054-11 |
0.325 |
|
| 2011 |
Bard-Chapeau EA, Li S, Ding J, Zhang SS, Zhu HH, Princen F, Fang DD, Han T, Bailly-Maitre B, Poli V, Varki NM, Wang H, Feng GS. Ptpn11/Shp2 acts as a tumor suppressor in hepatocellular carcinogenesis. Cancer Cell. 19: 629-39. PMID 21575863 DOI: 10.1016/J.Ccr.2011.03.023 |
0.505 |
|
| 2011 |
Zhu HH, Ji K, Alderson N, He Z, Li S, Liu W, Zhang DE, Li L, Feng GS. Kit-Shp2-Kit signaling acts to maintain a functional hematopoietic stem and progenitor cell pool. Blood. 117: 5350-61. PMID 21450902 DOI: 10.1182/Blood-2011-01-333476 |
0.572 |
|
| 2011 |
Lu Y, Xiong Y, Huo Y, Han J, Yang X, Zhang R, Zhu DS, Klein-Hessling S, Li J, Zhang X, Han X, Li Y, Shen B, He Y, Shibuya M, ... Feng GS, et al. Grb-2-associated binder 1 (Gab1) regulates postnatal ischemic and VEGF-induced angiogenesis through the protein kinase A-endothelial NOS pathway. Proceedings of the National Academy of Sciences of the United States of America. 108: 2957-62. PMID 21282639 DOI: 10.1073/Pnas.1009395108 |
0.35 |
|
| 2011 |
Fu J, Chen Y, Cao J, Luo T, Qian YW, Yang W, Ren YB, Su B, Cao GW, Yang Y, Yan YQ, Shen F, Wu MC, Feng GS, Wang HY. p28GANK overexpression accelerates hepatocellular carcinoma invasiveness and metastasis via phosphoinositol 3-kinase/AKT/hypoxia-inducible factor-1α pathways. Hepatology (Baltimore, Md.). 53: 181-92. PMID 21254169 DOI: 10.1002/Hep.24015 |
0.343 |
|
| 2011 |
Bauler TJ, Kamiya N, Lapinski PE, Langewisch E, Mishina Y, Wilkinson JE, Feng GS, King PD. Development of severe skeletal defects in induced SHP-2-deficient adult mice: a model of skeletal malformation in humans with SHP-2 mutations. Disease Models & Mechanisms. 4: 228-39. PMID 21068439 DOI: 10.1242/Dmm.006130 |
0.312 |
|
| 2011 |
Ruan X, Li Z, Zhang Y, Yang L, Pan Y, Wang Z, Feng GS, Chen Y. Apolipoprotein A-I possesses an anti-obesity effect associated with increase of energy expenditure and up-regulation of UCP1 in brown fat. Journal of Cellular and Molecular Medicine. 15: 763-72. PMID 20193037 DOI: 10.1111/J.1582-4934.2010.01045.X |
0.3 |
|
| 2011 |
Ma P, Mali R, Zeng L, Martin H, Ramdas B, He Y, Sims E, Ghosh J, Nabinger SC, Li S, Munugalavadla V, Chatterjee A, Sandusky G, Craig A, Bunting KD, ... Feng G, et al. KIT Induced Myeloproliferative Disease Is Dependent on PI3Kinase and SHP2 Phosphatase: Identification of SHP2 As a Druggable Target for Treating MPD and AML Blood. 118: 868-868. DOI: 10.1182/Blood.V118.21.868.868 |
0.643 |
|
| 2010 |
Zhu Y, Park J, Hu X, Zheng K, Li H, Cao Q, Feng GS, Qiu M. Control of oligodendrocyte generation and proliferation by Shp2 protein tyrosine phosphatase. Glia. 58: 1407-14. PMID 20648636 DOI: 10.1002/Glia.21016 |
0.4 |
|
| 2010 |
Zheng Y, An H, Yao M, Hou J, Yu Y, Feng G, Cao X. Scaffolding adaptor protein Gab1 is required for TLR3/4- and RIG-I-mediated production of proinflammatory cytokines and type I IFN in macrophages Journal of Immunology. 184: 6447-6456. PMID 20435932 DOI: 10.4049/Jimmunol.0901750 |
0.326 |
|
| 2010 |
Cai Z, Feng GS, Zhang X. Temporal requirement of the protein tyrosine phosphatase Shp2 in establishing the neuronal fate in early retinal development. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 4110-9. PMID 20237281 DOI: 10.1523/Jneurosci.4364-09.2010 |
0.357 |
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| 2010 |
Pan Y, Carbe C, Powers A, Feng GS, Zhang X. Sprouty2-modulated Kras signaling rescues Shp2 deficiency during lens and lacrimal gland development. Development (Cambridge, England). 137: 1085-93. PMID 20215346 DOI: 10.1242/Dev.042820 |
0.423 |
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| 2010 |
Weng T, Mao F, Wang Y, Sun Q, Li R, Yang G, Zhang X, Luo J, Feng GS, Yang X. Osteoblastic molecular scaffold Gab1 is required for maintaining bone homeostasis. Journal of Cell Science. 123: 682-9. PMID 20124419 DOI: 10.1242/Jcs.058396 |
0.359 |
|
| 2010 |
Huang H, Waldon Z, Chan G, Zhu H, Steen H, Feng G, Neel B, Cantor A. Tyrosine Phosphorylation of Runx1 In Megakaryocytes by Src Family Kinases Blood. 116: 742-742. DOI: 10.1182/Blood.V116.21.742.742 |
0.582 |
|
| 2010 |
Zhu HH, Ji K, Alderson N, He Z, Li S, Li L, Feng G. Coordinated Regulation of Embryonic and Adult Hematopoietic Stem Cell Activity by PTPN11/Shp2. Blood. 116: 2630-2630. DOI: 10.1182/Blood.V116.21.2630.2630 |
0.532 |
|
| 2010 |
Futami M, Zhu Q, Feng G, Neel B, Corey SJ. The G-CSF Receptor Requires Gab2-Mediated Recruitment of the Tyrosine Phosphatase Shp2 to Promote Lyn-Dependent Proliferation. Blood. 116: 1555-1555. DOI: 10.1182/Blood.V116.21.1555.1555 |
0.415 |
|
| 2009 |
McPherson VA, Sharma N, Everingham S, Smith J, Zhu HH, Feng GS, Craig AW. SH2 domain-containing phosphatase-2 protein-tyrosine phosphatase promotes Fc epsilon RI-induced activation of Fyn and Erk pathways leading to TNF alpha release from bone marrow-derived mast cells. Journal of Immunology (Baltimore, Md. : 1950). 183: 4940-7. PMID 19786542 DOI: 10.4049/Jimmunol.0900702 |
0.586 |
|
| 2009 |
Hagihara K, Zhang EE, Ke YH, Liu G, Liu JJ, Rao Y, Feng GS. Shp2 acts downstream of SDF-1alpha/CXCR4 in guiding granule cell migration during cerebellar development. Developmental Biology. 334: 276-84. PMID 19635473 DOI: 10.1016/J.Ydbio.2009.07.029 |
0.694 |
|
| 2009 |
Zhang SS, Hao E, Yu J, Liu W, Wang J, Levine F, Feng GS. Coordinated regulation by Shp2 tyrosine phosphatase of signaling events controlling insulin biosynthesis in pancreatic beta-cells. Proceedings of the National Academy of Sciences of the United States of America. 106: 7531-6. PMID 19380737 DOI: 10.1073/Pnas.0811715106 |
0.343 |
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| 2009 |
Wu D, Pang Y, Ke Y, Yu J, He Z, Tautz L, Mustelin T, Ding S, Huang Z, Feng GS. A conserved mechanism for control of human and mouse embryonic stem cell pluripotency and differentiation by shp2 tyrosine phosphatase. Plos One. 4: e4914. PMID 19290061 DOI: 10.1371/Journal.Pone.0004914 |
0.61 |
|
| 2009 |
Yu J, Zhang SS, Saito K, Williams S, Arimura Y, Ma Y, Ke Y, Baron V, Mercola D, Feng GS, Adamson E, Mustelin T. PTEN regulation by Akt-EGR1-ARF-PTEN axis. The Embo Journal. 28: 21-33. PMID 19057511 DOI: 10.1038/Emboj.2008.238 |
0.584 |
|
| 2009 |
Princen F, Bard E, Sheikh F, Zhang SS, Wang J, Zago WM, Wu D, Trelles RD, Bailly-Maitre B, Kahn CR, Chen Y, Reed JC, Tong GG, Mercola M, Chen J, ... Feng GS, et al. Deletion of Shp2 tyrosine phosphatase in muscle leads to dilated cardiomyopathy, insulin resistance, and premature death. Molecular and Cellular Biology. 29: 378-88. PMID 19001090 DOI: 10.1128/Mcb.01661-08 |
0.356 |
|
| 2009 |
Nabinger SC, He Y, Yin F, Zhang X, Senbanjo L, Fukuda S, Yu M, Feng G, Zhang Z, Kapur R, Chan RJ. Targeting the Protein Phosphatase, Shp2, Reduces FLT3-ITD-Induced Hyperproliferation of Murine Hematopoietic Progenitors. Blood. 114: 827-827. DOI: 10.1182/Blood.V114.22.827.827 |
0.624 |
|
| 2008 |
Mitra S, Beach C, Feng GS, Plattner R. SHP-2 is a novel target of Abl kinases during cell proliferation. Journal of Cell Science. 121: 3335-46. PMID 18827006 DOI: 10.1242/Jcs.035691 |
0.436 |
|
| 2008 |
Dawson MI, Xia Z, Jiang T, Ye M, Fontana JA, Farhana L, Patel B, Xue LP, Bhuiyan M, Pellicciari R, Macchiarulo A, Nuti R, Zhang XK, Han YH, Tautz L, ... ... Feng GS, et al. Adamantyl-substituted retinoid-derived molecules that interact with the orphan nuclear receptor small heterodimer partner: effects of replacing the 1-adamantyl or hydroxyl group on inhibition of cancer cell growth, induction of cancer cell apoptosis, and inhibition of SRC homology 2 domain-containing protein tyrosine phosphatase-2 activity. Journal of Medicinal Chemistry. 51: 5650-62. PMID 18759424 DOI: 10.1021/Jm800456K |
0.388 |
|
| 2008 |
Luo X, Feng L, Jiang X, Xiao F, Wang Z, Feng GS, Chen Y. Characterization of the topology and functional domains of RKTG. The Biochemical Journal. 414: 399-406. PMID 18547165 DOI: 10.1042/Bj20080948 |
0.344 |
|
| 2008 |
Krajewska M, Banares S, Zhang EE, Huang X, Scadeng M, Jhala US, Feng GS, Krajewski S. Development of diabesity in mice with neuronal deletion of Shp2 tyrosine phosphatase. The American Journal of Pathology. 172: 1312-24. PMID 18403587 DOI: 10.2353/Ajpath.2008.070594 |
0.549 |
|
| 2008 |
Pan Y, Carbe C, Powers A, Zhang EE, Esko JD, Grobe K, Feng GS, Zhang X. Bud specific N-sulfation of heparan sulfate regulates Shp2-dependent FGF signaling during lacrimal gland induction. Development (Cambridge, England). 135: 301-10. PMID 18077586 DOI: 10.1242/Dev.014829 |
0.622 |
|
| 2008 |
Wu D, Pang Y, Ke Y, He Z, Feng G. A conserved role of Shp2 in regulation of human and mouse ES cell differentiation Cell Research. 18: S27-S27. DOI: 10.1038/Cr.2008.117 |
0.599 |
|
| 2007 |
Ruhul Amin AR, Uddin Biswas MH, Senga T, Feng GS, Kannagi R, Agarwal ML, Hamaguchi M. A role for SHPS-1/SIRPalpha in Concanavalin A-dependent production of MMP-9. Genes to Cells : Devoted to Molecular & Cellular Mechanisms. 12: 1023-33. PMID 17825046 DOI: 10.1111/J.1365-2443.2007.01115.X |
0.447 |
|
| 2007 |
Ke Y, Zhang EE, Hagihara K, Wu D, Pang Y, Klein R, Curran T, Ranscht B, Feng GS. Deletion of Shp2 in the brain leads to defective proliferation and differentiation in neural stem cells and early postnatal lethality. Molecular and Cellular Biology. 27: 6706-17. PMID 17646384 DOI: 10.1128/Mcb.01225-07 |
0.709 |
|
| 2007 |
Ni S, Zhao C, Feng GS, Paulson RF, Correll PH. A novel Stat3 binding motif in Gab2 mediates transformation of primary hematopoietic cells by the Stk/Ron receptor tyrosine kinase in response to Friend virus infection. Molecular and Cellular Biology. 27: 3708-15. PMID 17353274 DOI: 10.1128/Mcb.01838-06 |
0.537 |
|
| 2007 |
Ke Y, Wu D, Princen F, Nguyen T, Pang Y, Lesperance J, Muller WJ, Oshima RG, Feng GS. Role of Gab2 in mammary tumorigenesis and metastasis. Oncogene. 26: 4951-60. PMID 17310989 DOI: 10.1038/sj.onc.1210315 |
0.499 |
|
| 2007 |
Feng GS. Shp2-mediated molecular signaling in control of embryonic stem cell self-renewal and differentiation. Cell Research. 17: 37-41. PMID 17211446 DOI: 10.1038/Sj.Cr.7310140 |
0.42 |
|
| 2007 |
Chan RJ, Feng GS. PTPN11 is the first identified proto-oncogene that encodes a tyrosine phosphatase. Blood. 109: 862-7. PMID 17053061 DOI: 10.1182/Blood-2006-07-028829 |
0.561 |
|
| 2006 |
An H, Zhao W, Hou J, Zhang Y, Xie Y, Zheng Y, Xu H, Qian C, Zhou J, Yu Y, Liu S, Feng G, Cao X. SHP-2 phosphatase negatively regulates the TRIF adaptor protein-dependent type I interferon and proinflammatory cytokine production. Immunity. 25: 919-28. PMID 17157040 DOI: 10.1016/J.Immuni.2006.10.014 |
0.414 |
|
| 2006 |
Nguyen TV, Ke Y, Zhang EE, Feng GS. Conditional deletion of Shp2 tyrosine phosphatase in thymocytes suppresses both pre-TCR and TCR signals. Journal of Immunology (Baltimore, Md. : 1950). 177: 5990-6. PMID 17056523 DOI: 10.4049/Jimmunol.177.9.5990 |
0.707 |
|
| 2006 |
Ke Y, Lesperance J, Zhang EE, Bard-Chapeau EA, Oshima RG, Muller WJ, Feng GS. Conditional deletion of Shp2 in the mammary gland leads to impaired lobulo-alveolar outgrowth and attenuated Stat5 activation. The Journal of Biological Chemistry. 281: 34374-80. PMID 16959766 DOI: 10.1074/Jbc.M607325200 |
0.702 |
|
| 2006 |
Dong XP, Li XM, Gao TM, Zhang EE, Feng GS, Xiong WC, Mei L. Shp2 is dispensable in the formation and maintenance of the neuromuscular junction. Neuro-Signals. 15: 53-63. PMID 16837792 DOI: 10.1159/000094484 |
0.528 |
|
| 2006 |
Bard-Chapeau EA, Yuan J, Droin N, Long S, Zhang EE, Nguyen TV, Feng GS. Concerted functions of Gab1 and Shp2 in liver regeneration and hepatoprotection. Molecular and Cellular Biology. 26: 4664-74. PMID 16738330 DOI: 10.1128/Mcb.02253-05 |
0.622 |
|
| 2006 |
Feng GS. Shp2 as a therapeutic target for leptin resistance and obesity. Expert Opinion On Therapeutic Targets. 10: 135-42. PMID 16441233 DOI: 10.1517/14728222.10.1.135 |
0.315 |
|
| 2006 |
Ni S, Xu J, Teal H, Feng G, Paulson RF, Correll PH. A Noval Stat3 Binding Site in Gab2 Mediates Hematopoietic Transformation by Friend Erythroleukemia Virus. Blood. 108: 465-465. DOI: 10.1182/Blood.V108.11.465.465 |
0.421 |
|
| 2005 |
Xu R, Yu Y, Zheng S, Zhao X, Dong Q, He Z, Liang Y, Lu Q, Fang Y, Gan X, Xu X, Zhang S, Dong Q, Zhang X, Feng GS. Overexpression of Shp2 tyrosine phosphatase is implicated in leukemogenesis in adult human leukemia. Blood. 106: 3142-9. PMID 16030196 DOI: 10.1182/Blood-2004-10-4057 |
0.436 |
|
| 2005 |
Bard-Chapeau EA, Hevener AL, Long S, Zhang EE, Olefsky JM, Feng GS. Deletion of Gab1 in the liver leads to enhanced glucose tolerance and improved hepatic insulin action. Nature Medicine. 11: 567-71. PMID 15821749 DOI: 10.1038/Nm1227 |
0.557 |
|
| 2005 |
Wang FM, Liu HQ, Liu SR, Tang SP, Yang L, Feng GS. SHP-2 promoting migration and metastasis of MCF-7 with loss of E-cadherin, dephosphorylation of FAK and secretion of MMP-9 induced by IL-1beta in vivo and in vitro. Breast Cancer Research and Treatment. 89: 5-14. PMID 15666191 DOI: 10.1007/S10549-004-1002-Z |
0.38 |
|
| 2004 |
Zhang EE, Chapeau E, Hagihara K, Feng GS. Neuronal Shp2 tyrosine phosphatase controls energy balance and metabolism. Proceedings of the National Academy of Sciences of the United States of America. 101: 16064-9. PMID 15520383 DOI: 10.1073/Pnas.0405041101 |
0.626 |
|
| 2004 |
Ivins Zito C, Kontaridis MI, Fornaro M, Feng GS, Bennett AM. SHP-2 regulates the phosphatidylinositide 3'-kinase/Akt pathway and suppresses caspase 3-mediated apoptosis. Journal of Cellular Physiology. 199: 227-36. PMID 15040005 DOI: 10.1002/Jcp.10446 |
0.343 |
|
| 2004 |
Sun Y, Yuan J, Liu H, Shi Z, Baker K, Vuori K, Wu J, Feng GS. Role of Gab1 in UV-induced c-Jun NH2-terminal kinase activation and cell apoptosis. Molecular and Cellular Biology. 24: 1531-9. PMID 14749370 DOI: 10.1128/Mcb.24.4.1531-1539.2004 |
0.319 |
|
| 2004 |
Chan RJ, You M, Feng GS. Identification of trans-acting factors by electrophoretic mobility shift assay. Methods in Molecular Biology (Clifton, N.J.). 249: 7-20. PMID 14573887 DOI: 10.1385/1-59259-667-3:7 |
0.452 |
|
| 2004 |
Feng G. Mutated SHP and AML in leukemias Blood. 103: 1982-1983. DOI: 10.1182/Blood-2004-01-0060 |
0.424 |
|
| 2003 |
Ruhul Amin AR, Oo ML, Senga T, Suzuki N, Feng GS, Hamaguchi M. SH2 domain containing protein tyrosine phosphatase 2 regulates concanavalin A-dependent secretion and activation of matrix metalloproteinase 2 via the extracellular signal-regulated kinase and p38 pathways. Cancer Research. 63: 6334-9. PMID 14559821 |
0.349 |
|
| 2003 |
von Wichert G, Haimovich B, Feng GS, Sheetz MP. Force-dependent integrin-cytoskeleton linkage formation requires downregulation of focal complex dynamics by Shp2. The Embo Journal. 22: 5023-35. PMID 14517241 DOI: 10.1093/Emboj/Cdg492 |
0.322 |
|
| 2003 |
Zhao C, Ma H, Bossy-Wetzel E, Lipton SA, Zhang Z, Feng GS. GC-GAP, a Rho family GTPase-activating protein that interacts with signaling adapters Gab1 and Gab2. The Journal of Biological Chemistry. 278: 34641-53. PMID 12819203 DOI: 10.1074/Jbc.M304594200 |
0.552 |
|
| 2003 |
Chan RJ, Johnson SA, Li Y, Yoder MC, Feng GS. A definitive role of Shp-2 tyrosine phosphatase in mediating embryonic stem cell differentiation and hematopoiesis. Blood. 102: 2074-80. PMID 12791646 DOI: 10.1182/Blood-2003-04-1171 |
0.625 |
|
| 2003 |
MacGillivray M, Herrera-Abreu MT, Chow CW, Shek C, Wang Q, Vachon E, Feng GS, Siminovitch KA, McCulloch CA, Downey GP. The protein tyrosine phosphatase SHP-2 regulates interleukin-1-induced ERK activation in fibroblasts. The Journal of Biological Chemistry. 278: 27190-8. PMID 12721296 DOI: 10.1074/Jbc.M213083200 |
0.382 |
|
| 2003 |
Chen Y, Wen R, Yang S, Schuman J, Zhang EE, Yi T, Feng GS, Wang D. Identification of Shp-2 as a Stat5A phosphatase. The Journal of Biological Chemistry. 278: 16520-7. PMID 12615921 DOI: 10.1074/Jbc.M210572200 |
0.638 |
|
| 2002 |
Wu TR, Hong YK, Wang XD, Ling MY, Dragoi AM, Chung AS, Campbell AG, Han ZY, Feng GS, Chin YE. SHP-2 is a dual-specificity phosphatase involved in Stat1 dephosphorylation at both tyrosine and serine residues in nuclei. The Journal of Biological Chemistry. 277: 47572-80. PMID 12270932 DOI: 10.1074/Jbc.M207536200 |
0.465 |
|
| 2002 |
Shen R, Ouyang YB, Qu CK, Alonso A, Sperzel L, Mustelin T, Kaplan MH, Feng GS. Grap negatively regulates T-cell receptor-elicited lymphocyte proliferation and interleukin-2 induction. Molecular and Cellular Biology. 22: 3230-6. PMID 11971956 |
0.369 |
|
| 2001 |
Wu CJ, O'Rourke DM, Feng GS, Johnson GR, Wang Q, Greene MI. The tyrosine phosphatase SHP-2 is required for mediating phosphatidylinositol 3-kinase/Akt activation by growth factors. Oncogene. 20: 6018-25. PMID 11593409 DOI: 10.1038/Sj.Onc.1204699 |
0.476 |
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| 2001 |
Qu C, Nguyen S, Chen J, Feng G. Requirement of Shp-2 tyrosine phosphatase in lymphoid and hematopoietic cell development Blood. 97: 911-914. PMID 11159516 DOI: 10.1182/Blood.V97.4.911 |
0.386 |
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| 2001 |
You M, Flick LM, Yu D, Feng GS. Modulation of the nuclear factor kappa B pathway by Shp-2 tyrosine phosphatase in mediating the induction of interleukin (IL)-6 by IL-1 or tumor necrosis factor. The Journal of Experimental Medicine. 193: 101-10. PMID 11136824 DOI: 10.1084/Jem.193.1.101 |
0.537 |
|
| 2000 |
Schoenwaelder SM, Petch LA, Williamson D, Shen R, Feng GS, Burridge K. The protein tyrosine phosphatase Shp-2 regulates RhoA activity. Current Biology : Cb. 10: 1523-6. PMID 11114521 DOI: 10.1016/S0960-9822(00)00831-9 |
0.329 |
|
| 2000 |
Shi ZQ, Yu DH, Park M, Marshall M, Feng GS. Molecular mechanism for the Shp-2 tyrosine phosphatase function in promoting growth factor stimulation of Erk activity. Molecular and Cellular Biology. 20: 1526-36. PMID 10669730 DOI: 10.1128/Mcb.20.5.1526-1536.2000 |
0.596 |
|
| 1999 |
Feng GS. Shp-2 tyrosine phosphatase: Signaling one cell or many Experimental Cell Research. 253: 47-54. PMID 10579910 DOI: 10.1006/Excr.1999.4668 |
0.438 |
|
| 1999 |
Tanowitz M, Si J, Yu DH, Feng GS, Mei L. Regulation of neuregulin-mediated acetylcholine receptor synthesis by protein tyrosine phosphatase SHP2. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 19: 9426-35. PMID 10531446 |
0.556 |
|
| 1999 |
Kim CH, Qu CK, Hangoc G, Cooper S, Anzai N, Feng GS, Broxmeyer HE. Abnormal chemokine-induced responses of immature and mature hematopoietic cells from motheaten mice implicate the protein tyrosine phosphatase SHP-1 in chemokine responses. The Journal of Experimental Medicine. 190: 681-90. PMID 10477552 DOI: 10.1084/Jem.190.5.681 |
0.323 |
|
| 1999 |
Zhao C, Yu DH, Shen R, Feng GS. Gab2, a new pleckstrin homology domain-containing adapter protein, acts to uncouple signaling from ERK kinase to Elk-1. The Journal of Biological Chemistry. 274: 19649-54. PMID 10391903 DOI: 10.1074/Jbc.274.28.19649 |
0.659 |
|
| 1999 |
You M, Yu DH, Feng GS. Shp-2 tyrosine phosphatase functions as a negative regulator of the interferon-stimulated Jak/STAT pathway. Molecular and Cellular Biology. 19: 2416-24. PMID 10022928 DOI: 10.1128/Mcb.19.3.2416 |
0.575 |
|
| 1998 |
Oehrl W, Kardinal C, Ruf S, Adermann K, Groffen J, Feng GS, Blenis J, Tan TH, Feller SM. The germinal center kinase (GCK)-related protein kinases HPK1 and KHS are candidates for highly selective signal transducers of Crk family adapter proteins. Oncogene. 17: 1893-901. PMID 9788432 DOI: 10.1038/Sj.Onc.1202108 |
0.397 |
|
| 1998 |
Qu CK, Feng GS. Shp-2 has a positive regulatory role in ES cell differentiation and proliferation. Oncogene. 17: 433-9. PMID 9696036 DOI: 10.1038/sj.onc.1201920 |
0.314 |
|
| 1998 |
Yu DH, Qu CK, Henegariu O, Lu X, Feng GS. Protein-tyrosine phosphatase Shp-2 regulates cell spreading, migration, and focal adhesion. The Journal of Biological Chemistry. 273: 21125-31. PMID 9694867 DOI: 10.1074/jbc.273.33.21125 |
0.552 |
|
| 1998 |
Shi Z, Lu W, Feng G. The Shp-2 Tyrosine Phosphatase Has Opposite Effects in Mediating the Activation of Extracellular Signal-regulated and c-Jun NH2-terminal Mitogen-activated Protein Kinases Journal of Biological Chemistry. 273: 4904-4908. PMID 9478933 DOI: 10.1074/Jbc.273.9.4904 |
0.496 |
|
| 1998 |
Kim SO, Jiang J, Yi W, Feng GS, Frank SJ. Involvement of the Src homology 2-containing tyrosine phosphatase SHP-2 in growth hormone signaling Journal of Biological Chemistry. 273: 2344-2354. PMID 9442080 DOI: 10.1074/Jbc.273.4.2344 |
0.484 |
|
| 1997 |
Tang J, Feng GS, Li W. Induced direct binding of the adapter protein Nck to the GTPase-activating protein-associated protein p62 by epidermal growth factor. Oncogene. 15: 1823-32. PMID 9362449 DOI: 10.1038/Sj.Onc.1201351 |
0.37 |
|
| 1997 |
Tauchi T, Miyazawa K, Feng GS, Broxmeyer HE, Toyama K. A coiled-coil tetramerization domain of BCR-ABL is essential for the interactions of SH2-containing signal transduction molecules. The Journal of Biological Chemistry. 272: 1389-94. PMID 8995449 DOI: 10.1074/Jbc.272.2.1389 |
0.399 |
|
| 1997 |
Yin T, Shen R, Feng G, Yang Y. Molecular characterization of specific interactions between SHP-2 phosphatase and JAK tyrosine kinases. Journal of Biological Chemistry. 272: 1032-1037. PMID 8995399 DOI: 10.1074/Jbc.272.2.1032 |
0.416 |
|
| 1996 |
Feng G, Ouyang Y, Hu D, Shi Z, Gentz R, Ni J. Grap Is a Novel SH3-SH2-SH3 Adaptor Protein That Couples Tyrosine Kinases to the Ras Pathway Journal of Biological Chemistry. 271: 12129-12132. PMID 8647802 DOI: 10.1074/Jbc.271.21.12129 |
0.404 |
|
| 1996 |
Marengère LE, Waterhouse P, Duncan GS, Mittrücker HW, Feng GS, Mak TW. Regulation of T cell receptor signaling by tyrosine phosphatase SYP association with CTLA-4. Science (New York, N.Y.). 272: 1170-3. PMID 8638161 DOI: 10.1126/Science.272.5265.1170 |
0.399 |
|
| 1994 |
Feng G, Pawson T. Phosphotyrosine phosphatases with SH2 domains: regulators of signal transduction Trends in Genetics. 10: 54-58. PMID 8191586 DOI: 10.1016/0168-9525(94)90149-X |
0.393 |
|
| 1993 |
Kozlowski M, Mlinaric-Rascan I, Feng G, Shen R, Pawson T, Siminovitch KA. Expression and catalytic activity of the tyrosine phosphatase PTP1C is severely impaired in motheaten and viable motheaten mice. Journal of Experimental Medicine. 178: 2157-2163. PMID 8245788 DOI: 10.1084/Jem.178.6.2157 |
0.361 |
|
| 1993 |
Feng G, Hui C, Pawson T. SH2-containing phosphotyrosine phosphatase as a target of protein-tyrosine kinases Science. 259: 1607-1611. PMID 8096088 DOI: 10.1126/Science.8096088 |
0.425 |
|
| 1993 |
Kazlauskas A, Feng GS, Pawson T, Valius M. The 64-kDa protein that associates with the platelet-derived growth factor receptor beta subunit via Tyr-1009 is the SH2-containing phosphotyrosine phosphatase Syp. Proceedings of the National Academy of Sciences of the United States of America. 90: 6939-43. PMID 7688466 DOI: 10.1073/Pnas.90.15.6939 |
0.377 |
|
| 1991 |
Taylor MW, Feng G. Relationship between interferon-gamma, indoleamine 2,3-dioxygenase, and tryptophan catabolism. The Faseb Journal. 5: 2516-2522. DOI: 10.1096/Fasebj.5.11.1907934 |
0.305 |
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