Dehua Yu, PhD - Publications

AstraZeneca LP, Canóvanas, Canóvanas, Puerto Rico 

30 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2016 Yang L, Yu D, Mo R, Zhang J, Hua H, Hu L, Feng Y, Wang S, Zhang WY, Yin N, Mo XM. The Succinate Receptor GPR91 Is Involved in Pressure Overload-Induced Ventricular Hypertrophy. Plos One. 11: e0147597. PMID 26824665 DOI: 10.1371/journal.pone.0147597  0.36
2016 Zhou XQ, Yu DY, Shao XY, Zhang SQ, Wang S. Research and applications of viscoelastic vibration damping materials: A review Composite Structures. 136: 460-480. DOI: 10.1016/j.compstruct.2015.10.014  0.36
2015 Gavine PR, Wang M, Yu D, Hu E, Huang C, Xia J, Su X, Fan J, Zhang T, Ye Q, Zheng L, Zhu G, Qian Z, Luo Q, Hou YY, et al. Identification and validation of dysregulated MAPK7 (ERK5) as a novel oncogenic target in squamous cell lung and esophageal carcinoma. Bmc Cancer. 15: 454. PMID 26040563 DOI: 10.1186/s12885-015-1455-y  0.36
2015 Long Z, Yu D, Liu Y, Du N, Tao Y, Mei L, Guo Z, Liang X. The influence of organic sample solvents on the separation efficiency of basic compounds under strong cation exchange mode. Analytica Chimica Acta. 872: 77-83. PMID 25892072 DOI: 10.1016/j.aca.2014.12.057  0.36
2015 Yu DH, Tang L, Dong H, Dong Z, Zhang L, Fu J, Su X, Zhang T, Fu H, Han L, Xie L, Chen H, Qian Z, Zhu G, Wang J, et al. Oncogenic HER2 fusions in gastric cancer. Journal of Translational Medicine. 13: 116. PMID 25889497 DOI: 10.1186/s12967-015-0476-2  0.36
2014 Qian Z, Zhu G, Tang L, Wang M, Zhang L, Fu J, Huang C, Fan S, Sun Y, Lv J, Dong H, Gao B, Su X, Yu D, Zang J, et al. Whole genome gene copy number profiling of gastric cancer identifies PAK1 and KRAS gene amplification as therapy targets. Genes, Chromosomes & Cancer. 53: 883-94. PMID 24935174 DOI: 10.1002/gcc.22196  0.36
2014 Luo Q, Tang L, Lin H, Huang J, Zhang T, Liu Y, Wang J, Zhan P, Yin X, Su X, Ji Q, Yu D, Xu L. The oncogenic role of PKCiota gene amplification and overexpression in Chinese non-small cell lung cancer. Lung Cancer (Amsterdam, Netherlands). 84: 190-5. PMID 24636699 DOI: 10.1016/j.lungcan.2013.08.029  0.36
2014 Li J, Han S, Qian Z, Su X, Fan S, Fu J, Liu Y, Yin X, Gao Z, Zhang J, Yu DH, Ji Q. Genetic amplification of PPME1 in gastric and lung cancer and its potential as a novel therapeutic target. Cancer Biology & Therapy. 15: 128-34. PMID 24253382 DOI: 10.4161/cbt.27146  0.36
2014 Yu DH, Zhang X, Wang H, Zhang L, Chen H, Hu M, Dong Z, Zhu G, Qian Z, Fan J, Su X, Xu Y, Zheng L, Dong H, Yin X, et al. The essential role of TNIK gene amplification in gastric cancer growth Oncogenesis. 3. DOI: 10.1038/oncsis.2014.2  0.36
2013 Li J, Davies BR, Han S, Zhou M, Bai Y, Zhang J, Xu Y, Tang L, Wang H, Liu YJ, Yin X, Ji Q, Yu DH. The AKT inhibitor AZD5363 is selectively active in PI3KCA mutant gastric cancer, and sensitizes a patient-derived gastric cancer xenograft model with PTEN loss to Taxotere. Journal of Translational Medicine. 11: 241. PMID 24088382 DOI: 10.1186/1479-5876-11-241  0.36
2012 Davies BR, Greenwood H, Dudley P, Crafter C, Yu DH, Zhang J, Li J, Gao B, Ji Q, Maynard J, Ricketts SA, Cross D, Cosulich S, Chresta CC, Page K, et al. Preclinical pharmacology of AZD5363, an inhibitor of AKT: pharmacodynamics, antitumor activity, and correlation of monotherapy activity with genetic background. Molecular Cancer Therapeutics. 11: 873-87. PMID 22294718 DOI: 10.1158/1535-7163.MCT-11-0824-T  0.36
2011 Sun S, Wang X, Wang C, Nawaz A, Wei W, Li J, Wang L, Yu DH. Arctigenin suppresses unfolded protein response and sensitizes glucose deprivation-mediated cytotoxicity of cancer cells. Planta Medica. 77: 141-5. PMID 20717870 DOI: 10.1055/s-0030-1250179  0.36
2008 Yu DH, Macdonald J, Liu G, Lee AS, Ly M, Davis T, Ke N, Zhou D, Wong-Staal F, Li QX. Pyrvinium targets the unfolded protein response to hypoglycemia and its anti-tumor activity is enhanced by combination therapy. Plos One. 3: e3951. PMID 19079611 DOI: 10.1371/journal.pone.0003951  0.36
2008 Falkenstein IA, Cheng L, Wong-Staal F, Tammewar AM, Barron EC, Silva GA, Li QX, Yu D, Hysell M, Liu G, Ke N, Macdonald JE, Freeman WR. Toxicity and intraocular properties of a novel long-acting anti-proliferative and anti-angiogenic compound IMS2186. Current Eye Research. 33: 599-609. PMID 18600493 DOI: 10.1080/02713680802226582  0.36
2008 Li QX, Yu DH, Liu G, Ke N, McKelvy J, Wong-Staal F. Selective anticancer strategies via intervention of the death pathways relevant to cell transformation. Cell Death and Differentiation. 15: 1197-210. PMID 18437165 DOI: 10.1038/cdd.2008.48  0.36
2008 Zhou D, Wang C, Zhang J, Bliesath J, He QS, Ke N, Yu D, Li Q, Zhang LH, Wong-Staal F. Generation of shRNA pool library: a revision of the biological technique from the viewpoint of chemistry. Chembiochem : a European Journal of Chemical Biology. 9: 1365-7. PMID 18435449 DOI: 10.1002/cbic.200800049  0.36
2008 Ke N, Ma H, Diedrich G, Chionis J, Liu G, Yu DH, Wong-Staal F, Li QX. Biochemical characterization of genetic mutations of GPR56 in patients with bilateral frontoparietal polymicrogyria (BFPP). Biochemical and Biophysical Research Communications. 366: 314-20. PMID 18042463 DOI: 10.1016/j.bbrc.2007.11.071  0.36
2007 Ke N, Sundaram R, Liu G, Chionis J, Fan W, Rogers C, Awad T, Grifman M, Yu D, Wong-Staal F, Li QX. Orphan G protein-coupled receptor GPR56 plays a role in cell transformation and tumorigenesis involving the cell adhesion pathway. Molecular Cancer Therapeutics. 6: 1840-50. PMID 17575113 DOI: 10.1158/1535-7163.MCT-07-0066  0.36
2006 Ke N, Zhou D, Chatterton JE, Liu G, Chionis J, Zhang J, Tsugawa L, Lynn R, Yu D, Meyhack B, Wong-Staal F, Li QX. A new inducible RNAi xenograft model for assessing the staged tumor response to mTOR silencing. Experimental Cell Research. 312: 2726-34. PMID 16765945 DOI: 10.1016/j.yexcr.2006.05.001  0.36
2006 Yu DH, Macdonald J, Josephs S, Liu Q, Nguy V, Tor Y, Wong-Staal F, Li QX. MDDD, a 4,9-diazapyrenium derivative, is selectively toxic to glioma cells by inducing growth arrest at G0/G1 independently of p53. Investigational New Drugs. 24: 489-98. PMID 16633716 DOI: 10.1007/s10637-006-7590-1  0.36
2006 Yu DH, Fan W, Liu G, Nguy V, Chatterton JE, Long S, Ke N, Meyhack B, Bruengger A, Brachat A, Wong-Staal F, Li QX. PHTS, a novel putative tumor suppressor, is involved in the transformation reversion of HeLaHF cells independently of the p53 pathway. Experimental Cell Research. 312: 865-76. PMID 16413018 DOI: 10.1016/j.yexcr.2005.12.006  0.36
2005 Yu DH, Chatterton JE, Bliesath JR, Sundaram R, Ke N, Nguy V, Meyhack B, Wong-Staal F, Li QX. A 96-well surrogate survival assay coupled with a special short interfering RNA vector for assessing cancer gene targets with enhanced signal/noise ratio and its utility in HTS for cancer therapeutic targets. Assay and Drug Development Technologies. 3: 401-11. PMID 16180995 DOI: 10.1089/adt.2005.3.401  0.36
2004 Ke N, Claassen G, Yu DH, Albers A, Fan W, Tan P, Grifman M, Hu X, Defife K, Nguy V, Meyhack B, Brachat A, Wong-Staal F, Li QX. Nuclear hormone receptor NR4A2 is involved in cell transformation and apoptosis. Cancer Research. 64: 8208-12. PMID 15548686 DOI: 10.1158/0008-5472.CAN-04-2134  0.36
2004 Ke N, Albers A, Claassen G, Yu DH, Chatterton JE, Hu X, Meyhack B, Wong-Staal F, Li QX. One-week 96-well soft agar growth assay for cancer target validation. Biotechniques. 36: 826-8, 830, 832-3. PMID 15152603  0.36
2001 You M, Flick LM, Yu D, Feng GS. Modulation of the nuclear factor kappa B pathway by Shp-2 tyrosine phosphatase in mediating the induction of interleukin (IL)-6 by IL-1 or tumor necrosis factor. The Journal of Experimental Medicine. 193: 101-10. PMID 11136824 DOI: 10.1084/jem.193.1.101  0.36
2000 Shi ZQ, Yu DH, Park M, Marshall M, Feng GS. Molecular mechanism for the Shp-2 tyrosine phosphatase function in promoting growth factor stimulation of Erk activity. Molecular and Cellular Biology. 20: 1526-36. PMID 10669730 DOI: 10.1128/MCB.20.5.1526-1536.2000  0.36
1999 Tanowitz M, Si J, Yu DH, Feng GS, Mei L. Regulation of neuregulin-mediated acetylcholine receptor synthesis by protein tyrosine phosphatase SHP2. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 19: 9426-35. PMID 10531446  0.36
1999 Zhao C, Yu DH, Shen R, Feng GS. Gab2, a new pleckstrin homology domain-containing adapter protein, acts to uncouple signaling from ERK kinase to Elk-1. The Journal of Biological Chemistry. 274: 19649-54. PMID 10391903 DOI: 10.1074/jbc.274.28.19649  0.36
1999 You M, Yu DH, Feng GS. Shp-2 tyrosine phosphatase functions as a negative regulator of the interferon-stimulated Jak/STAT pathway. Molecular and Cellular Biology. 19: 2416-24. PMID 10022928  0.36
1998 Yu DH, Qu CK, Henegariu O, Lu X, Feng GS. Protein-tyrosine phosphatase Shp-2 regulates cell spreading, migration, and focal adhesion. The Journal of Biological Chemistry. 273: 21125-31. PMID 9694867 DOI: 10.1074/jbc.273.33.21125  0.36
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