Alexandre Mourot - Publications

Affiliations: 
1999-2004 Bioorganic chemistry Université Louis Pasteur (Strasbourg) 
 2005-2007 Biophysical Chemistry Max Planck Institute of Biophysics, Frankfurt am Main, Hessen, Germany 
 2007-2012 Life Science Dept University of California, Berkeley, Berkeley, CA, United States 
 2012-2014 Biology of Adaptive Processes Université Pierre et Marie Curie (Paris VI) 
 2014-2021 Neuroscience Paris Seine Sorbonne Université, Paris, France 
 2021- Brain Plasticity ESPCI Paris, PSL Research University, Paris 
Area:
Ion channels, optogenetics, nicotinic receptor

47 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Mondoloni S, Nguyen C, Vicq E, Ciscato M, Jehl J, Durand-de Cuttoli R, Torquet N, Tolu S, Pons S, Maskos U, Marti F, Faure P, Mourot A. Prolonged nicotine exposure reduces aversion to the drug in mice by altering nicotinic transmission in the interpeduncular nucleus. Elife. 12. PMID 37249215 DOI: 10.7554/eLife.80767  0.759
2023 Bousseyrol E, Didienne S, Takillah S, Prevost-Solié C, Come M, Ahmed Yahia T, Mondoloni S, Vicq E, Tricoire L, Mourot A, Naudé J, Faure P. Dopaminergic and prefrontal dynamics co-determine mouse decisions in a spatial gambling task. Cell Reports. 42: 112523. PMID 37200189 DOI: 10.1016/j.celrep.2023.112523  0.731
2021 Dongelmans M, Durand-de Cuttoli R, Nguyen C, Come M, Duranté EK, Lemoine D, Brito R, Ahmed Yahia T, Mondoloni S, Didienne S, Bousseyrol E, Hannesse B, Reynolds LM, Torquet N, Dalkara D, ... ... Mourot A, et al. Chronic nicotine increases midbrain dopamine neuron activity and biases individual strategies towards reduced exploration in mice. Nature Communications. 12: 6945. PMID 34836948 DOI: 10.1038/s41467-021-27268-7  0.804
2021 Nguyen C, Mondoloni S, Le Borgne T, Centeno I, Come M, Jehl J, Solié C, Reynolds LM, Durand-de Cuttoli R, Tolu S, Valverde S, Didienne S, Hannesse B, Fiancette JF, Pons S, ... ... Mourot A, et al. Nicotine inhibits the VTA-to-amygdala dopamine pathway to promote anxiety. Neuron. PMID 34242565 DOI: 10.1016/j.neuron.2021.06.013  0.807
2020 Lemoine D, Mondoloni S, Tange J, Lambolez B, Faure P, Taly A, Tricoire L, Mourot A. Probing the ionotropic activity of glutamate GluD2 receptor in HEK cells with genetically-engineered photopharmacology. Elife. 9. PMID 33112237 DOI: 10.7554/eLife.59026  0.807
2020 Durand-de Cuttoli R, Chauhan PS, Pétriz Reyes A, Faure P, Mourot A, Ellis-Davies GCR. Optofluidic control of rodent learning using cloaked caged glutamate. Proceedings of the National Academy of Sciences of the United States of America. PMID 32152102 DOI: 10.1073/Pnas.1920869117  0.605
2020 Belkaid M, Bousseyrol E, Durand-de Cuttoli R, Dongelmans M, Duranté EK, Yahia TA, Didienne S, Hanesse B, Come M, Mourot A, Naudé J, Sigaud O, Faure P. Author Correction: Mice adaptively generate choice variability in a deterministic task. Communications Biology. 3: 54. PMID 32005936 DOI: 10.1038/s42003-020-0785-8  0.465
2020 Belkaid M, Bousseyrol E, Durand-de Cuttoli R, Dongelmans M, Duranté EK, Ahmed Yahia T, Didienne S, Hanesse B, Come M, Mourot A, Naudé J, Sigaud O, Faure P. Mice adaptively generate choice variability in a deterministic task. Communications Biology. 3: 34. PMID 31965053 DOI: 10.1038/s42003-020-0759-x  0.503
2019 Mondoloni S, Durand-de Cuttoli R, Mourot A. Cell-Specific Neuropharmacology. Trends in Pharmacological Sciences. PMID 31400823 DOI: 10.1016/J.Tips.2019.07.007  0.8
2019 Paoletti P, Ellis-Davies GCR, Mourot A. Optical control of neuronal ion channels and receptors. Nature Reviews. Neuroscience. PMID 31289380 DOI: 10.1038/S41583-019-0197-2  0.561
2018 Forget B, Scholze P, Langa F, Morel C, Pons S, Mondoloni S, Besson M, Durand-de Cuttoli R, Hay A, Tricoire L, Lambolez B, Mourot A, Faure P, Maskos U. A Human Polymorphism in CHRNA5 Is Linked to Relapse to Nicotine Seeking in Transgenic Rats. Current Biology : Cb. PMID 30293722 DOI: 10.1016/J.Cub.2018.08.044  0.808
2018 Durand-de Cuttoli R, Mondoloni S, Marti F, Lemoine D, Nguyen C, Naudé J, d'Izarny-Gargas T, Pons S, Maskos U, Trauner D, Kramer RH, Faure P, Mourot A. Manipulating midbrain dopamine neurons and reward-related behaviors with light-controllable nicotinic acetylcholine receptors. Elife. 7. PMID 30176987 DOI: 10.7554/Elife.37487  0.818
2018 Torquet N, Marti F, Campart C, Tolu S, Nguyen C, Oberto V, Benallaoua M, Naudé J, Didienne S, Debray N, Jezequel S, Le Gouestre L, Hannesse B, Mariani J, Mourot A, et al. Social interactions impact on the dopaminergic system and drive individuality. Nature Communications. 9: 3081. PMID 30082725 DOI: 10.1038/S41467-018-05526-5  0.553
2018 Cuttoli RD, Mondoloni S, Marti F, Lemoine D, Nguyen C, Naudé J, d'Izarny-Gargas T, Pons S, Maskos U, Trauner D, Kramer RH, Faure P, Mourot A. Author response: Manipulating midbrain dopamine neurons and reward-related behaviors with light-controllable nicotinic acetylcholine receptors Elife. DOI: 10.7554/Elife.37487.021  0.808
2017 Durand-de Cuttoli R, Mondoloni S, Mourot A. [Optically dissecting brain nicotinic receptor function with photo-controllable designer receptors]. Biologie Aujourd'Hui. 211: 173-188. PMID 29236669 DOI: 10.1051/Jbio/2017022  0.828
2017 Takillah S, Naudé J, Didienne S, Sebban C, Decros B, Schenker E, Spedding M, Mourot A, Mariani J, Faure P. Acute Stress Affects the Expression of Hippocampal Mu Oscillations in an Age-Dependent Manner. Frontiers in Aging Neuroscience. 9: 295. PMID 29033825 DOI: 10.3389/Fnagi.2017.00295  0.527
2017 Mourot A, Herold C, Kienzler MA, Kramer RH. Understanding and improving photo-control of ion channels in nociceptors with azobenzene photoswitches. British Journal of Pharmacology. PMID 28635081 DOI: 10.1111/Bph.13923  0.633
2016 Lemoine D, Cuttoli RD, Mourot A. Optogenetic Control of Mammalian Ion Channels with Chemical Photoswitches. Methods in Molecular Biology (Clifton, N.J.). 1408: 177-93. PMID 26965123 DOI: 10.1007/978-1-4939-3512-3_12  0.74
2016 Naudé J, Tolu S, Dongelmans M, Torquet N, Valverde S, Rodriguez G, Pons S, Maskos U, Mourot A, Marti F, Faure P. Nicotinic receptors in the ventral tegmental area promote uncertainty-seeking. Nature Neuroscience. PMID 26780509 DOI: 10.1038/Nn.4223  0.65
2014 Lin WC, Davenport CM, Mourot A, Vytla D, Smith CM, Medeiros KA, Chambers JJ, Kramer RH. Engineering a light-regulated GABAA receptor for optical control of neural inhibition. Acs Chemical Biology. 9: 1414-9. PMID 24819442 DOI: 10.1021/Cb500167U  0.813
2013 Kramer RH, Mourot A, Adesnik H. Optogenetic pharmacology for control of native neuronal signaling proteins. Nature Neuroscience. 16: 816-23. PMID 23799474 DOI: 10.1038/Nn.3424  0.647
2013 Mourot A, Tochitsky I, Kramer RH. Light at the end of the channel: optical manipulation of intrinsic neuronal excitability with chemical photoswitches. Frontiers in Molecular Neuroscience. 6: 5. PMID 23518818 DOI: 10.3389/Fnmol.2013.00005  0.809
2013 Mourot A, Fehrentz T, Kramer RH. Photochromic potassium channel blockers: design and electrophysiological characterization. Methods in Molecular Biology (Clifton, N.J.). 995: 89-105. PMID 23494374 DOI: 10.1007/978-1-62703-345-9_7  0.624
2012 Bhargava Y, Rettinger J, Mourot A. Allosteric nature of P2X receptor activation probed by photoaffinity labelling. British Journal of Pharmacology. 167: 1301-10. PMID 22725669 DOI: 10.1111/J.1476-5381.2012.02083.X  0.767
2012 Mourot A, Fehrentz T, Le Feuvre Y, Smith CM, Herold C, Dalkara D, Nagy F, Trauner D, Kramer RH. Rapid optical control of nociception with an ion-channel photoswitch. Nature Methods. 9: 396-402. PMID 22343342 DOI: 10.1038/Nmeth.1897  0.643
2012 Tochitsky I, Banghart MR, Mourot A, Yao JZ, Gaub B, Kramer RH, Trauner D. Optochemical control of genetically engineered neuronal nicotinic acetylcholine receptors. Nature Chemistry. 4: 105-11. PMID 22270644 DOI: 10.1038/Nchem.1234  0.828
2012 Donato L, Mourot A, Davenport CM, Herbivo C, Warther D, Léonard J, Bolze F, Nicoud JF, Kramer RH, Goeldner M, Specht A. Water-soluble, donor-acceptor biphenyl derivatives in the 2-(o-nitrophenyl)propyl series: highly efficient two-photon uncaging of the neurotransmitter γ-aminobutyric acid at λ = 800 nm. Angewandte Chemie (International Ed. in English). 51: 1840-3. PMID 22238209 DOI: 10.1002/Anie.201106559  0.765
2012 Herold C, Mourot A, Kramer RH. Mechanism of Action of the Photoswitch Molecule QAQ Biophysical Journal. 102: 137a. DOI: 10.1016/J.Bpj.2011.11.756  0.673
2012 Davenport CM, Lin W, Mourot A, Vytla D, Smith CM, Medeiros KA, Chambers JJ, Kramer RH. Optical Control of Neuronal Inhibition with Genetically Engineered Light Inhibited GABAA Receptors (Li-GABARs) Biophysical Journal. 102: 111a. DOI: 10.1016/J.Bpj.2011.11.626  0.805
2011 Mourot A, Kienzler MA, Banghart MR, Fehrentz T, Huber FM, Stein M, Kramer RH, Trauner D. Tuning photochromic ion channel blockers. Acs Chemical Neuroscience. 2: 536-43. PMID 22860175 DOI: 10.1021/Cn200037P  0.786
2011 Lin W, Mourot A, Vytla D, Smith CM, Medeiros KA, Chambers JJ, Kramer RH. Optogenetic GABAA Receptors: Controlling Neural Inhibition with Light Biophysical Journal. 100: 24a-25a. DOI: 10.1016/J.Bpj.2010.12.340  0.752
2010 Warther D, Gug S, Specht A, Bolze F, Nicoud JF, Mourot A, Goeldner M. Two-photon uncaging: New prospects in neuroscience and cellular biology. Bioorganic & Medicinal Chemistry. 18: 7753-8. PMID 20554207 DOI: 10.1016/J.Bmc.2010.04.084  0.682
2010 Fehrentz T, Mourot A, Kienzler M, Tsunozaki M, Banghart M, Bautista D, Trauner D, Kramer RH. Light Control of Cell Excitability Using a Photochromic Blocker for Voltage-Gated Ion Channels Biophysical Journal. 98: 113a. DOI: 10.1016/J.Bpj.2009.12.4207  0.799
2010 Mourot A, Fehrentz T, Kienzler M, Tochitsky I, Banghart MR, Trauner D, Kramer RH. Photopharmacology: Controlling Native Voltage-Gated Ion Channels with Light Biophysical Journal. 98: 212a. DOI: 10.1016/J.Bpj.2009.12.1143  0.779
2009 Banghart MR, Mourot A, Fortin DL, Yao JZ, Kramer RH, Trauner D. Photochromic blockers of voltage-gated potassium channels. Angewandte Chemie (International Ed. in English). 48: 9097-101. PMID 19882609 DOI: 10.1002/Anie.200904504  0.766
2009 Schulz P, Dueck B, Mourot A, Hatahet L, Fendler K. Measuring ion channels on solid supported membranes. Biophysical Journal. 97: 388-96. PMID 19580777 DOI: 10.1016/J.Bpj.2009.04.022  0.509
2009 Mourot A, Banghart MR, Fortin DL, Trauner D, Kramer RH. Light At The End Of The Channel: Photochromic Blockers For Optical Control Of Ion Channels In Individual Cells Biophysical Journal. 96: 179a. DOI: 10.1016/J.Bpj.2008.12.836  0.788
2009 Banghart MR, Mourot A, Fortin DL, Kramer RH, Trauner D. Discovery Of Photochromic Ligands That Block Voltage-gated K+ Channels At The Internal TEA Binding Site Biophysical Journal. 96: 23a. DOI: 10.1016/J.Bpj.2008.12.1022  0.781
2009 Banghart M, Mourot A, Fortin D, Yao J, Kramer R, Trauner D. Photochrome Liganden für spannungsgesteuerte Kaliumkanäle Angewandte Chemie. 121: 9261-9265. DOI: 10.1002/Ange.200904504  0.723
2008 Krieger F, Mourot A, Araoz R, Kotzyba-Hibert F, Molgó J, Bamberg E, Goeldner M. Fluorescent agonists for the Torpedo nicotinic acetylcholine receptor. Chembiochem : a European Journal of Chemical Biology. 9: 1146-53. PMID 18386276 DOI: 10.1002/Cbic.200700757  0.802
2008 Mourot A, Bamberg E, Rettinger J. Agonist- and competitive antagonist-induced movement of loop 5 on the alpha subunit of the neuronal alpha4beta4 nicotinic acetylcholine receptor. Journal of Neurochemistry. 105: 413-24. PMID 18047559 DOI: 10.1111/J.1471-4159.2007.05151.X  0.665
2007 Mourot A, Kramer RH. Staples, tape measures, and bungee cords: a variety of bifunctional reagents for understanding and controlling ion channels. Acs Chemical Biology. 2: 451-3. PMID 17649968 DOI: 10.1021/Cb700135A  0.601
2006 Mourot A, Rodrigo J, Bertrand S, Bertrand D, Goeldner M, Kotzyba-Hibert F. Reorganization of the nicotinic acetylcholine receptor during desensitization probed with a photoactivatable agonist. Journal of Molecular Neuroscience : Mn. 30: 13-4. PMID 17192607 DOI: 10.1385/Jmn:30:1:13  0.8
2006 Mourot A, Kotzyba-Hibert F, Goeldner M, Bamberg E. Photo-induced covalent attachment of agonists as a tool to study allosteric mechanisms of nicotinic acetylcholine receptors. Journal of Molecular Neuroscience : Mn. 30: 3-4. PMID 17192602 DOI: 10.1385/Jmn:30:1:3  0.827
2006 Mourot A, Grutter T, Goeldner M, Kotzyba-Hibert F. Dynamic structural investigations on the torpedo nicotinic acetylcholine receptor by time-resolved photoaffinity labeling. Chembiochem : a European Journal of Chemical Biology. 7: 570-83. PMID 16538695 DOI: 10.1002/Cbic.200500526  0.817
2006 Mourot A, Rodrigo J, Kotzyba-Hibert F, Bertrand S, Bertrand D, Goeldner M. Probing the reorganization of the nicotinic acetylcholine receptor during desensitization by time-resolved covalent labeling using [3H]AC5, a photoactivatable agonist. Molecular Pharmacology. 69: 452-61. PMID 16269537 DOI: 10.1124/Mol.105.017566  0.799
2002 Mourot A, Kotzyba-Hibert F, Doris E, Goeldner M. New and convenient synthesis of a tritiated photoactivatable nicotinic agonist: [3H]-AC5 Journal of Labelled Compounds and Radiopharmaceuticals. 45: 943-953. DOI: 10.1002/Jlcr.614  0.789
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