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Prabhat Arya - Publications

Affiliations: 
1985 CSIR-National Chemical Laboratory, Pune, India 
 1989-2009 National Research Council, Canada, Ottawa, Ontario, Canada 
 1994-2009 University of Ottawa, Ottawa, ON, Canada 
 2009-2018 Dr. Reddy’s Institute of Life Sciences, University of Hyderabad 
 2018- SignMod Biotech 
Area:
Biochemistry, bioorganic chemistry, chemical biology
Website:
http://www.signmod.org/leaders.html
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42 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2018 Guduru SKR, Arya P. Synthesis and biological evaluation of rapamycin-derived, next generation small molecules. Medchemcomm. 9: 27-43. PMID 30108899 DOI: 10.1039/C7Md00474E  0.502
2017 Jogula S, Soorneedi AR, Gaddam J, Chamakuri S, Deora GS, Indarapu RK, Ramgopal MK, Dravida S, Arya P. Geldanamycin-inspired compounds induce direct trans-differentiation of human mesenchymal stem cells to neurons. European Journal of Medicinal Chemistry. 135: 110-116. PMID 28441579 DOI: 10.1016/J.Ejmech.2017.03.082  0.8
2016 Konda S, Khatravath M, Mallurwar NK, Rao P, Sripelly S, Iqbal J, Arya P. Stereoselective Synthesis of the C27-C35 Eribulin Fragment and Its Utilization in Building Structurally Diverse Macrocycles Synthesis (Germany). 48: 1663-1683. DOI: 10.1055/S-0035-1561431  0.789
2016 Dasari B, Fufa T, Aeluri M, Gaddam J, Deora GS, Gaunitz F, Kitambi SS, Arya P. Macrocyclic Toolbox from Epothilone Fragment Identifies a Compound Showing Molecular Interactions with Actin and Novel Promoters of Apoptosis in Patient-derived Brain Tumor Cells Asian Journal of Organic Chemistry. 5: 976-980. DOI: 10.1002/Ajoc.201600126  0.809
2015 Chamakuri S, Jogula S, Arya P. Regio- and Stereocontrolled Dieckmann Approach to Treprostinil-Inspired, Polycyclic Scaffold For Building Macrocyclic Diversity. Acs Combinatorial Science. 17: 437-41. PMID 26167941 DOI: 10.1021/Acscombsci.5B00076  0.843
2015 Guduru SK, Jimmidi R, Deora GS, Arya P. Stereoselective synthesis of rapamycin fragment to build a macrocyclic toolbox. Organic Letters. 17: 480-3. PMID 25583255 DOI: 10.1021/Ol5034833  0.8
2015 Aeluri M, Dasari B, Arya P. Divergent approach to building a latrunculin family derived hybrid macrocyclic toolbox. Organic Letters. 17: 472-5. PMID 25583127 DOI: 10.1021/Ol503465P  0.819
2015 Jimmidi R, Guduru SK, Arya P. Practical stereoselective synthesis of eribulin fragment toward building a hybrid macrocyclic toolbox. Organic Letters. 17: 468-71. PMID 25583003 DOI: 10.1021/Ol503464S  0.825
2015 Dasari B, Jimmidi R, Arya P. Selected hybrid natural products as tubulin modulators. European Journal of Medicinal Chemistry. 94: 497-508. PMID 25455639 DOI: 10.1016/J.Ejmech.2014.10.062  0.785
2014 Aeluri M, Chamakuri S, Dasari B, Guduru SK, Jimmidi R, Jogula S, Arya P. Small molecule modulators of protein-protein interactions: selected case studies. Chemical Reviews. 114: 4640-94. PMID 24673632 DOI: 10.1021/Cr4004049  0.703
2014 Jimmidi R, Shroff GK, Satyanarayana M, Reddy BR, Kapireddy J, Sawant MA, Sitaswad SL, Arya P, Mitra P. Prevention of mitochondrial membrane permeabilization and pancreatic β-cell death by an enantioenriched, macrocyclic small molecule European Journal of Organic Chemistry. 2014: 1151-1156. DOI: 10.1002/Ejoc.201301769  0.788
2013 Reddy Guduru SK, Chamakuri S, Chandrasekar G, Kitambi SS, Arya P. Tetrahydroquinoline-derived macrocyclic toolbox: the discovery of antiangiogenesis agents in zebrafish assay. Acs Medicinal Chemistry Letters. 4: 666-70. PMID 24900727 DOI: 10.1021/Ml400026N  0.813
2013 Aeluri M, Pramanik C, Chetia L, Mallurwar NK, Balasubramanian S, Chandrasekar G, Kitambi SS, Arya P. 14-Membered macrocyclic ring-derived toolbox: the identification of small molecule inhibitors of angiogenesis and early embryo development in zebrafish assay. Organic Letters. 15: 436-9. PMID 23331174 DOI: 10.1021/Ol3032126  0.817
2013 Dasari B, Jogula S, Borhade R, Balasubramanian S, Chandrasekar G, Kitambi SS, Arya P. Macrocyclic glycohybrid toolbox identifies novel antiangiogenesis agents from zebrafish assay. Organic Letters. 15: 432-5. PMID 23331160 DOI: 10.1021/Ol3032297  0.792
2013 Jogula S, Dasari B, Khatravath M, Chandrasekar G, Kitambi SS, Arya P. Building a Macrocyclic Toolbox fromC-Linked Carbohydrates Identifies Antiangiogenesis Agents from Zebrafish Assay European Journal of Organic Chemistry. 2013: 5036-5040. DOI: 10.1002/Ejoc.201300548  0.787
2013 Chamakuri S, Guduru SKR, Pamu S, Chandrasekar G, Kitambi SS, Arya P. A Modular Approach to Build Macrocyclic Diversity in Aminoindoline Scaffolds Identifies Antiangiogenesis Agents from a Zebrafish Assay European Journal of Organic Chemistry. 2013: 3959-3964. DOI: 10.1002/Ejoc.201300409  0.78
2013 Aeluri M, Gaddam J, Trinath DVKS, Chandrasekar G, Kitambi SS, Arya P. An Intramolecular Heck Approach To Obtain 17-Membered Macrocyclic Diversity and the Identification of an Antiangiogenesis Agent from a Zebrafish Assay European Journal of Organic Chemistry. 2013: 3955-3958. DOI: 10.1002/Ejoc.201300408  0.82
2009 Nandy JP, Prakesch M, Khadem S, Reddy PT, Sharma U, Arya P. Advances in solution- and solid-phase synthesis toward the generation of natural product-like libraries. Chemical Reviews. 109: 1999-2060. PMID 19249849 DOI: 10.1021/Cr800188V  0.779
2009 Poondra RR, Kumar NN, Bijian K, Prakesch M, Campagna-Slater V, Reayi A, Reddy PT, Choudhry A, Barnes ML, Leek DM, Daroszewska M, Lougheed C, Xu B, Schapira M, Alaoui-Jamali MA, ... Arya P, et al. Discovery of indoline-based, natural-product-like compounds as probes of focal adhesion kinase signaling pathways. Journal of Combinatorial Chemistry. 11: 303-9. PMID 19146410 DOI: 10.1021/Cc8001525  0.366
2008 Prakesch M, Bijian K, Campagna-Slater V, Quevillon S, Joseph R, Wei CQ, Sesmilo E, Reayi A, Poondra RR, Barnes ML, Leek DM, Xu B, Lougheed C, Schapira M, Alaoui-Jamali M, ... Arya P, et al. Building skeletally diverse architectures on the Indoline Scaffold: the discovery of a chemical probe of focal adhesion kinase signaling networks. Bioorganic & Medicinal Chemistry. 16: 9596-602. PMID 18835181 DOI: 10.1016/J.Bmc.2008.09.025  0.815
2008 Brochu JL, Prakesch M, Enright GD, Leek DM, Arya P. Reagent-based, modular, tandem Michael approach for obtaining different indoline alkaloid-inspired polycyclic architectures. Journal of Combinatorial Chemistry. 10: 405-20. PMID 18419163 DOI: 10.1021/Cc800036W  0.819
2008 Nandy JP, Rakic B, Sarma BV, Babu N, Lefrance M, Enright GD, Leek DM, Daniel K, Sabourin LA, Arya P. Benzofuran-derived cyclic beta-amino acid scaffold for building a diverse set of flavonoid-like probes and the discovery of a cell motility inhibitor. Organic Letters. 10: 1143-6. PMID 18302395 DOI: 10.1021/Ol800050G  0.322
2006 Reddy PT, Quevillon S, Gan Z, Forbes N, Leek DM, Arya P. Solution- and solid-phase, modular approaches for obtaining different natural product-like polycyclic architectures from an aminoindoline scaffold for combinatorial chemistry. Journal of Combinatorial Chemistry. 8: 856-71. PMID 17096575 DOI: 10.1021/cc0600573  0.848
2006 Prakesch M, Srivastava S, Leek DM, Arya P. Part 3. a novel stereocontrolled, in situ, solution- and solid-phase, Aza Michael approach for high-throughput generation of tetrahydroaminoquinoline-derived natural-product-like architectures. Journal of Combinatorial Chemistry. 8: 762-73. PMID 16961412 DOI: 10.1021/cc060059n  0.32
2006 Prakesch M, Sharma U, Sharma M, Khadem S, Leek DM, Arya P. Part 1. modular approach to obtaining diverse tetrahydroquinoline-derived polycyclic skeletons for use in high-throughput generation of natural-product-like chemical probes. Journal of Combinatorial Chemistry. 8: 715-34. PMID 16961410 DOI: 10.1021/Cc060055I  0.857
2006 Arya P, Boyer J, Carré F, Corriu R, Lanneau G, Lapasset J, Perrot M, Priou C. Bildung und Reaktivität von Verbindungen mit Si-S- und Si-Se-Doppelbindungen; erste Röntgenstrukturanalyse eines Silanthions Angewandte Chemie. 101: 1069-1071. DOI: 10.1002/Ange.19891010826  0.495
2005 Gan Z, Reddy PT, Quevillon S, Couve-Bonnaire S, Arya P. Stereocontrolled solid-phase synthesis of a 90-membered library of indoline-alkaloid-like polycycles from an enantioenriched aminoindoline scaffold. Angewandte Chemie (International Ed. in English). 44: 1366-8. PMID 15674986 DOI: 10.1002/Anie.200462298  0.815
2004 Arya P, Couve-Bonnaire S, Durieux P, Laforce D, Kumar R, Leek DM. Solution- and solid-phase synthesis of natural product-like tetrahydroquinoline-based polycyclics having a medium size ring. Journal of Combinatorial Chemistry. 6: 735-45. PMID 15360208 DOI: 10.1021/cc049935s  0.457
2004 Khadem S, Joseph R, Rastegar M, Leek DM, Oudatchin KA, Arya P. A solution- and solid-phase approach to tetrahydroquinoline-derived polycyclics having a 10-membered ring. Journal of Combinatorial Chemistry. 6: 724-34. PMID 15360207 DOI: 10.1021/Cc049941O  0.851
2004 Couve-Bonnaire S, Chou DT, Gan Z, Arya P. A solid-phase, library synthesis of natural-product-like derivatives from an enantiomerically pure tetrahydroquinoline scaffold. Journal of Combinatorial Chemistry. 6: 73-7. PMID 14714987 DOI: 10.1021/cc030026x  0.367
2004 Arya P, Wei CQ, Barnes ML, Daroszewska M. A solid phase library synthesis of hydroxyindoline-derived tricyclic derivatives by Mitsunobu approach. Journal of Combinatorial Chemistry. 6: 65-72. PMID 14714986 DOI: 10.1021/cc0340067  0.446
2004 Arya P, Durieux P, Chen ZX, Joseph R, Leek DM. Stereoselective diversity-oriented solution and solid-phase synthesis of tetrahydroquinoline-based polycyclic derivatives. Journal of Combinatorial Chemistry. 6: 54-64. PMID 14714985 DOI: 10.1021/cc034053z  0.348
2002 Antebi S, Arya P, Manzer LE, Alper H. Carbonylation reactions of iodoarenes with PAMAM dendrimer-palladium catalysts immobilized on silica. The Journal of Organic Chemistry. 67: 6623-31. PMID 12227790 DOI: 10.1021/Jo020271N  0.371
2002 Arya P, Barkley A, Randell KD. Automated high-throughput synthesis of artificial glycopeptides. Small-molecule probes for chemical glycobiology. Journal of Combinatorial Chemistry. 4: 193-8. PMID 12005477  0.333
2002 Arya P, Joseph R, Chou DT. Toward high-throughput synthesis of complex natural product-like compounds in the genomics and proteomics age. Chemistry & Biology. 9: 145-56. PMID 11880029  0.396
2001 Arya P, Baek MG. Natural-product-like chiral derivatives by solid-phase synthesis Current Opinion in Chemical Biology. 5: 292-301. PMID 11479121 DOI: 10.1016/S1367-5931(00)00205-2  0.337
2001 Arya P, Panda G, Rao NV, Alper H, Bourque SC, Manzer LE. Solid-phase catalysis: a biomimetic approach toward ligands on dendritic arms to explore recyclable hydroformylation reactions. Journal of the American Chemical Society. 123: 2889-90. PMID 11456979 DOI: 10.1021/JA003854S  0.601
2001 Barkley A, Arya P. Combinatorial chemistry toward understanding the function(s) of carbohydrates and carbohydrate conjugates Chemistry - a European Journal. 7: 555-563. PMID 11261652 DOI: 10.1002/1521-3765(20010202)7:3<555::AID-CHEM555>3.0.CO;2-I  0.314
2000 Alper H, Arya P, Bourque SC, Jefferson GR, Manzer LE. Heck reaction using palladium complexed to dendrimers on silica Canadian Journal of Chemistry. 78: 920-924. DOI: 10.1139/V00-018  0.394
1998 Arya P, Ben RN, Qin H. Remote asymmtric induction: Synthesis of C-linked α-galactoserine and homoserine derivatives by electrophilic amination Tetrahedron Letters. 39: 6131-6134. DOI: 10.1016/S0040-4039(98)01295-7  0.357
1997 Arya P, Dion S, Shimizu GK. Stereoselective synthesis of neo-C-glycopeptide building blocks: Towards a flexible and control-oriented design as probes for carbohydrate-protein interactions Bioorganic & Medicinal Chemistry Letters. 7: 1537-1542. DOI: 10.1016/S0960-894X(97)00255-2  0.36
1997 Arya P, Ben RN. Combinatorial Chemistry for the Synthesis of Carbohydrate Libraries Angewandte Chemie International Edition in English. 36: 1280-1282. DOI: 10.1002/Anie.199712801  0.339
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