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Surajit Sinha - Publications

Affiliations: 
2006- IACS Kolkata 
Area:
Organic Synthesis, Chemical Biology, Drug discovery and delivery
Website:
http://iacs.res.in/faculty-profile.html?id=64#
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73 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Gupta S, Sharma SN, Kundu J, Pattanayak S, Sinha S. Morpholino oligonucleotide-mediated exon skipping for DMD treatment: Past insights, present challenges and future perspectives. Journal of Biosciences. 48. PMID 37846020  0.757
2023 Das A, Ghosh A, Kundu J, Egli M, Manoharan M, Sinha S. Synthesis and Biophysical Studies of High-Affinity Morpholino Oligomers Containing G-Clamp Analogs. The Journal of Organic Chemistry. 88: 15168-15175. PMID 37843026 DOI: 10.1021/acs.joc.3c01658  0.782
2023 Das U, Kundu J, Shaw P, Bose C, Ghosh A, Gupta S, Sarkar S, Bhadra J, Sinha S. Self-transfecting GMO-PMO chimera targeting enable gene silencing and suppresses tumor growth in 4T1 allografts in mouse. Molecular Therapy. Nucleic Acids. 32: 203-228. PMID 37078062 DOI: 10.1016/j.omtn.2023.03.011  0.755
2023 Kundu J, Ghosh U, Ghosh A, Pattanayak S, Das A, Sinha S. Synthesis of Chlorophosphoramidate Monomer Morpholinos and PMOs. Current Protocols. 3: e686. PMID 36802170 DOI: 10.1002/cpz1.686  0.79
2023 Ghosh A, Akabane-Nakata M, Kundu J, Harp JM, Madaoui M, Egli M, Manoharan M, Sinha S. Synthesis and Biophysical Properties of Phosphorodiamidate Piperidino Oligomers. Organic Letters. PMID 36734846 DOI: 10.1021/acs.orglett.2c04067  0.795
2023 Das A, Ghosh A, Sinha S. C5-pyrimidine-functionalized morpholino oligonucleotides exhibit differential binding affinity, target specificity and lipophilicity. Organic & Biomolecular Chemistry. PMID 36633261 DOI: 10.1039/d2ob01759h  0.759
2022 Das O, Kundu J, Ghosh A, Gautam A, Ghosh S, Chakraborty M, Masid A, Gauri SS, Mitra D, Dutta M, Mukherjee B, Sinha S, Bhaumik M. AUF-1 knockdown in mice undermines gut microbial butyrate-driven hypocholesterolemia through AUF-1-Dicer-1-mir-122 hierarchy. Frontiers in Cellular and Infection Microbiology. 12: 1011386. PMID 36601302 DOI: 10.3389/fcimb.2022.1011386  0.771
2022 Ghosh U, Gupta S, Sinha S. Synthesis of 5'-Thiol Functionalized Morpholino Oligo-Nucleotide and Subsequent Conjugation with IGT to Improve Delivery and Antisense Efficacy . Bioconjugate Chemistry. 34: 174-180. PMID 36538654 DOI: 10.1021/acs.bioconjchem.2c00587  0.803
2022 Gupta S, Das U, Sinha S. IGT mediated Nanog siRNA delivery in prostate cancer cells improves chemosensitization of Epirubicin in vitro. Bioorganic & Medicinal Chemistry Letters. 76: 129017. PMID 36209968 DOI: 10.1016/j.bmcl.2022.129017  0.486
2022 Kundu J, Ghosh A, Ghosh U, Das A, Nagar D, Pattanayak S, Ghose A, Sinha S. Synthesis of Phosphorodiamidate Morpholino Oligonucleotides Using Trityl and Fmoc Chemistry in an Automated Oligo Synthesizer. The Journal of Organic Chemistry. 87: 9466-9478. PMID 35839125 DOI: 10.1021/acs.joc.2c00265  0.779
2022 Gupta A, Gupta S, Das U, Sinha S. Guanidinium-Functionalized Flexible Azaproline Transporter for Efficient Intracellular Delivery of Proapoptotic Peptide and PDL1 Antisense Morpholino Oligo in Human Carcinoma Cells . Bioconjugate Chemistry. PMID 35486710 DOI: 10.1021/acs.bioconjchem.2c00129  0.63
2022 Mana T, Kundu J, Lahiri H, Bera S, Kolay J, Sinha S, Mukhopadhyay R. Molecularly resolved, label-free nucleic acid sensing at solid-liquid interface using non-ionic DNA analogues. Rsc Advances. 12: 9263-9274. PMID 35424880 DOI: 10.1039/d2ra00386d  0.702
2022 Bose C, Das U, Kuilya TK, Mondal J, Bhadra J, Banerjee P, Goswami RK, Sinha S. Cananginone Abrogates EMT in Breast Cancer Cells through Hedgehog Signaling. Chemistry & Biodiversity. e202100823. PMID 35298074 DOI: 10.1002/cbdv.202100823  0.753
2021 Gupta S, Qasim M, Gupta A, Kundu J, Sinha S. Structural Modifications to the Internal Oligoguanidinium Transporter Uncover Two Potent Analogues that Effectively Deliver the Proapoptotic Peptide in Multiple Cancer Cell Lines. Bioconjugate Chemistry. PMID 34915704 DOI: 10.1021/acs.bioconjchem.1c00456  0.795
2021 Banerjee I, Ghosh KC, Oheix E, Jean M, Naubron JV, Réglier M, Iranzo O, Sinha S. Synthesis of Protected 3,4- and 2,3-Dimercaptophenylalanines as Building Blocks for -Peptide Synthesis and Incorporation of the 3,4-Analogue in a Decapeptide Using Solid-Phase Synthesis. The Journal of Organic Chemistry. PMID 33491451 DOI: 10.1021/acs.joc.0c02359  0.627
2020 Kundu J, Banerjee P, Bose C, Das U, Ghosh U, Sinha S. Internal Oligoguanidinium Transporter: Mercury Free Scalable Synthesis, Improvement of Cellular Localization, Endosomal Escape, Mitochondrial Localization and Conjugation with Antisense Morpholino for NANOG Inhibition to Induce Chemosensitisation of Taxol in MCF-7 Cells. Bioconjugate Chemistry. PMID 32986398 DOI: 10.1021/acs.bioconjchem.0c00444  0.762
2019 Nandi B, Pattanayak S, Paul S, Kundu J, Sinha S. Synthesis of Nucleobase-Functionalized Morpholino Monomers. Methods in Molecular Biology (Clifton, N.J.). 1973: 107-130. PMID 31016698 DOI: 10.1007/978-1-4939-9216-4_7  0.787
2019 Ranjan A, Sinha S, Ayabe R, Wach M, Ruff S, Gupta S, McDonald J, Remmert K, Alexander I, Hernandez J. Abstract C44: MBD3 stabilizes MYC, leading to metastatic outgrowth of pancreatic cancer in the liver Cancer Research. 79. DOI: 10.1158/1538-7445.Panca19-C44  0.308
2019 Sinha S, Ayabe RI, Ranjan A, Wach M, Ruff S, Remmert K, Beek EV, Alexander I, McDonald JD, Gupta S, Li E, Hernandez J. Abstract A50: IMPACT inhibits metastatic outgrowth in pancreatic cancer by restraining GCN1-ATF4 signaling Cancer Research. 79. DOI: 10.1158/1538-7445.Panca19-A50  0.322
2019 Ghosh KC, Duttagupta I, Bose C, Banerjee P, Gayen AK, Sinha S. Synthesis and anticancer activities of proline-containing cyclic peptides and their linear analogs and congeners Synthetic Communications. 49: 221-236. DOI: 10.1080/00397911.2018.1550201  0.778
2019 Banerjee I, Ghosh KC, Sinha S. Pd-catalyzed C–H bond activation of Indoles for Suzuki reaction Journal of Chemical Sciences. 131: 1-9. DOI: 10.1007/S12039-019-1649-Y  0.593
2018 Sinha S, Khatra H, Khan PP, Pattanayak S, Bhadra J, Rather B, Chakrabarti S, Saha T. Hedgehog antagonist pyrimidine-indole hybrid molecule inhibits ciliogenesis through microtubule destabilization. Chembiochem : a European Journal of Chemical Biology. PMID 29363254 DOI: 10.1002/Cbic.201700631  0.773
2018 Ghosh KC, Banerjee I, Sinha S. Montmorillonite K10 catalyzed highly regioselective azidolysis of epoxides: A short and efficient synthesis of phenylglycine Synthetic Communications. 48: 2923-2934. DOI: 10.1080/00397911.2018.1524494  0.601
2018 Bhadra J, Kundu J, Ghosh KC, Sinha S. Corrigendum to “Synthesis of phosphorodiamidate morpholino oligonucleotides by H-phosphonate method” [Tetrahedron Lett. 56 (2015) 4565–4568] Tetrahedron Letters. 59: 1974-1975. DOI: 10.1016/J.Tetlet.2018.04.011  0.749
2017 Khatra H, Bose C, Sinha S. Discovery of hedgehog antagonists for cancer therapy. Current Medicinal Chemistry. PMID 28302010 DOI: 10.2174/0929867324666170316115500  0.783
2016 Bhadra J, Pattanayak S, Khan PP, Kundu J, Sinha S. Internal Oligoguanidinium-based Cellular Transporter Enhances Antisense Efficacy of Morpholinos in in vitro and Zebrafish model. Bioconjugate Chemistry. PMID 27625020 DOI: 10.1021/Acs.Bioconjchem.6B00252  0.766
2016 Khatra H, Kundu J, Khan PP, Duttagupta I, Pattanayak S, Sinha S. Piperazic acid derivatives inhibit Gli1 in Hedgehog signaling pathway. Bioorganic & Medicinal Chemistry Letters. PMID 27528433 DOI: 10.1016/J.Bmcl.2016.08.008  0.774
2016 Duttagupta I, Bhadra J, Das SK, Sinha S. Proteolytic stability of cyclic α-hydrazino acid containing peptides: a qualitative study Tetrahedron Letters. 57: 3858-3861. DOI: 10.1016/J.Tetlet.2016.07.050  0.767
2016 Duttagupta I, Ghosh KC, Sinha S. Chapter 2 – Synthetic Studies Toward Nonribosomal Peptides Studies in Natural Products Chemistry. 48: 29-64. DOI: 10.1016/B978-0-444-63602-7.00002-3  0.793
2015 Duttagupta I, Misra D, Bhunya S, Paul A, Sinha S. Cis-Trans Conformational Analysis of δ-Azaproline in Peptides. The Journal of Organic Chemistry. 80: 10585-604. PMID 26440300 DOI: 10.1021/Acs.Joc.5B01668  0.775
2015 Bhadra J, Pattanayak S, Sinha S. Synthesis of Morpholino Monomers, Chlorophosphoramidate Monomers, and Solid-Phase Synthesis of Short Morpholino Oligomers. Current Protocols in Nucleic Acid Chemistry / Edited by Serge L. Beaucage ... [Et Al.]. 62: 4.65.1-4.65.26. PMID 26380905 DOI: 10.1002/0471142700.Nc0465S62  0.806
2015 Bhadra J, Kundu J, Ghosh KC, Sinha S. Synthesis of phosphorodiamidate morpholino oligonucleotides by H-phosphonate method Tetrahedron Letters. 56: 4565-4568. DOI: 10.1016/J.Tetlet.2015.05.080  0.776
2014 Duttagupta I, Goswami K, Chatla P, Sinha S. Improved Synthesis of Cyclic α-Hydrazino Acids of Five- to Nine-Membered Rings and Optical Resolution of 5,6,7-Membered Ring Hydrazino Acids Synthetic Communications. 44: 2510-2519. DOI: 10.1080/00397911.2014.905601  0.793
2014 Pattanayak S, Khatra H, Saha S, Sinha S. A cationic morpholino antisense oligomer conjugate: synthesis, cellular uptake and inhibition of Gli1 in the hedgehog signalling pathway Rsc Adv.. 4: 1951-1954. DOI: 10.1039/C3Ra45257C  0.795
2014 Chakraborty A, Jyothi K, Sinha S. Palladium-catalyzed synthesis of 2-allylindole and 2-allylbenzofuran derivatives from 2-((trimethylsilyl)ethynyl)arenes Tetrahedron Letters. 55: 6795-6798. DOI: 10.1016/J.Tetlet.2014.10.049  0.692
2014 Paul S, Pattanayak S, Sinha S. Synthesis and cell transfection properties of cationic uracil-morpholino tetramer Tetrahedron Letters. 55: 1072-1076. DOI: 10.1016/J.Tetlet.2013.12.087  0.794
2013 Paul S, Jana S, Bhadra J, Sinha S. Photophysical studies and submicron ring formation of morpholino U-nucleoside monomers. Chemical Communications (Cambridge, England). 49: 11278-80. PMID 24154562 DOI: 10.1039/C3Cc45082A  0.783
2013 Chakraborty A, Goswami K, Adiyala A, Sinha S. Syntheses of Spiro[cyclopent[3]ene-1,3′-indole]s and Tetrahydrocyclohepta[b]indoles from 2,3-Disubstituted Indoles through Sigmatropic Rearrangement European Journal of Organic Chemistry. 2013: 7117-7127. DOI: 10.1002/Ejoc.201300888  0.796
2013 Goswami K, Chakraborty A, Sinha S. Synthesis of Optically Active Selenium-Containing Isotryptophan, Homoiso­tryptophan, and Homotryptophan European Journal of Organic Chemistry. 2013: 3645-3647. DOI: 10.1002/Ejoc.201300352  0.797
2013 Nandi B, Pattanayak S, Paul S, Sinha S. Synthesis of Nucleobase-Functionalized Morpholino-Modified Nucleoside Monomers Through Palladium-Catalyzed Cross-Coupling Reactions European Journal of Organic Chemistry. 2013: 1271-1286. DOI: 10.1002/Ejoc.201201384  0.799
2012 Pattanayak S, Paul S, Nandi B, Sinha S. Improved protocol for the synthesis of flexibly protected morpholino monomers from unprotected ribonucleosides. Nucleosides, Nucleotides & Nucleic Acids. 31: 763-82. PMID 23145948 DOI: 10.1080/15257770.2012.724491  0.798
2012 Goswami K, Duttagupta I, Sinha S. Synthesis of optically active 2- and 3- indolylglycine derivatives and their oxygen analogues. The Journal of Organic Chemistry. 77: 7081-5. PMID 22834412 DOI: 10.1021/Jo300708H  0.78
2012 Pattanayak S, Sinha S. Lithium bromide–DBU mediated synthesis of chlorophosphoramidate-activated morpholino nucleoside subunits Tetrahedron Letters. 53: 6714-6717. DOI: 10.1016/J.Tetlet.2012.09.126  0.801
2012 Paul S, Nandi B, Pattanayak S, Sinha S. Synthesis of 5-alkynylated uracil–morpholino monomers using Sonogashira coupling Tetrahedron Letters. 53: 4179-4183. DOI: 10.1016/J.Tetlet.2012.05.141  0.788
2012 Jana GK, Sinha S. Corrigendum to “Reductive Heck coupling: an efficient approach toward the iboga alkaloids. Synthesis of ibogamine, epiibogamine, and iboga analogs” [Tetrahedron Lett. 53 (2012) 1671–1674] Tetrahedron Letters. 53: 2575. DOI: 10.1016/J.Tetlet.2012.03.029  0.338
2012 Jana GK, Sinha S. Reductive Heck coupling: an efficient approach toward the iboga alkaloids. Synthesis of ibogamine, epiibogamine and iboga analogs Tetrahedron Letters. 53: 1671-1674. DOI: 10.1016/J.Tetlet.2012.01.097  0.39
2012 Duttagupta I, Goswami K, Sinha S. Synthesis of cyclic α-hydrazino acids Tetrahedron. 68: 8347-8357. DOI: 10.1016/J.Tet.2012.07.014  0.798
2012 Jana GK, Sinha S. Total synthesis of ibogaine, epiibogaine and their analogues Tetrahedron. 68: 7155-7165. DOI: 10.1016/J.Tet.2012.06.027  0.386
2012 Goswami K, Paul S, Bugde ST, Sinha S. Synthesis of optically active homotryptophan and its oxygen and sulfur analogues Tetrahedron. 68: 280-286. DOI: 10.1016/J.Tet.2011.10.055  0.772
2011 Jana GK, Paul S, Sinha S. Progress in the Synthesis of Iboga-alkaloids and their Congeners Organic Preparations and Procedures International. 43: 541-573. DOI: 10.1080/00304948.2011.629563  0.378
2011 Chakraborty A, Sinha S. Synthesis of 3-[2-(1,3-butadienyl)]-1H-indoles en route to murrapanine analogue Tetrahedron Letters. 52: 6635-6638. DOI: 10.1016/J.Tetlet.2011.10.003  0.688
2011 Paul S, Pattanayak S, Sinha S. Synthesis of new series of iboga analogues Tetrahedron Letters. 52: 6166-6169. DOI: 10.1016/J.Tetlet.2011.09.040  0.808
2011 Pattanayak S, Sinha S. Ceric ammonium nitrate-mediated detritylation of tritylated amines Tetrahedron Letters. 52: 34-37. DOI: 10.1016/J.Tetlet.2010.10.118  0.791
2011 Nandi B, Sinha S. Alkylation of acylmetalates with alkyl halides to prepare Fischer carbene complexes: an improved protocol Tetrahedron. 67: 106-113. DOI: 10.1016/J.Tet.2010.11.016  0.629
2010 Jana GK, Sinha S. A concise route to iboga-analogues via the formation of suitably substituted-2-indoles Tetrahedron Letters. 51: 1994-1996. DOI: 10.1016/J.Tetlet.2010.02.028  0.365
2010 Jana GK, Sinha S. Synthesis of iboga alkaloids by Pd-catalyzed heteroannulation of 2-iodoaniline with an internal alkyne as the key step Tetrahedron Letters. 51: 1441-1443. DOI: 10.1016/J.Tetlet.2010.01.037  0.336
2009 Ouyang X, Shestopalov IA, Sinha S, Zheng G, Pitt CL, Li WH, Olson AJ, Chen JK. Versatile synthesis and rational design of caged morpholinos. Journal of the American Chemical Society. 131: 13255-69. PMID 19708646 DOI: 10.1021/Ja809933H  0.615
2009 Hyman JM, Firestone AJ, Heine VM, Zhao Y, Ocasio CA, Han K, Sun M, Rack PG, Sinha S, Wu JJ, Solow-Cordero DE, Jiang J, Rowitch DH, Chen JK. Small-molecule inhibitors reveal multiple strategies for Hedgehog pathway blockade. Proceedings of the National Academy of Sciences of the United States of America. 106: 14132-7. PMID 19666565 DOI: 10.1073/Pnas.0907134106  0.776
2009 Cupido T, Rack PG, Firestone AJ, Hyman JM, Han K, Sinha S, Ocasio CA, Chen JK. The imidazopyridine derivative JK184 reveals dual roles for microtubules in Hedgehog signaling. Angewandte Chemie (International Ed. in English). 48: 2321-4. PMID 19222062 DOI: 10.1002/Anie.200805666  0.769
2007 Pavithra L, Rampalli S, Sinha S, Sreenath K, Pestell RG, Chattopadhyay S. Stabilization of SMAR1 mRNA by PGA2 involves a stem-loop structure in the 5′ UTR Nucleic Acids Research. 35: 6004-6016. PMID 17726044 DOI: 10.1093/Nar/Gkm649  0.31
2007 Shestopalov IA, Sinha S, Chen JK. Light-controlled gene silencing in zebrafish embryos. Nature Chemical Biology. 3: 650-1. PMID 17717538 DOI: 10.1038/Nchembio.2007.30  0.614
2006 Sinha S, Chen JK. Purmorphamine activates the Hedgehog pathway by targeting Smoothened. Nature Chemical Biology. 2: 29-30. PMID 16408088 DOI: 10.1038/Nchembio753  0.603
2005 Switzer C, Sinha S, Kim PH, Heuberger BD. A purine-like nickel(II) base pair for DNA. Angewandte Chemie (International Ed. in English). 44: 1529-32. PMID 15678435 DOI: 10.1002/Anie.200462047  0.757
2005 Sinha S, Tilve S, Chandrasekaran S. A convenient synthesis of trans -3-hydroxy-L-proline Arkivoc. 2005. DOI: 10.3998/Ark.5550190.0006.B18  0.589
2004 Chakraborty C, Nandi S, Sinha S. Overexpression, purification and characterization of recombinant salmon calcitonin, a therapeutic protein, in Streptomyces avermitilis. Protein and Peptide Letters. 11: 165-173. PMID 15078205 DOI: 10.2174/0929866043478266  0.302
2004 Sinha S, Kim PH, Switzer C. 2',5'-linked DNA is a template for polymerase-directed DNA synthesis. Journal of the American Chemical Society. 126: 40-1. PMID 14709049 DOI: 10.1021/Ja034986Z  0.67
2002 Chaput JC, Sinha S, Switzer C. 5-propynyluracil.diaminopurine: an efficient base-pair for non-enzymatic transcription of DNA. Chemical Communications (Cambridge, England). 1568-9. PMID 12170785 DOI: 10.1039/B204535D  0.716
2002 Bhat RG, Sinha S, Chandrasekaran S. Propargyloxycarbonyl (Poc) amino acid chlorides as efficient coupling reagents for the synthesis of 100% diastereopure peptides and resin bound tetrathiomolybdate as an effective deblocking agent for the Poc group. Chemical Communications (Cambridge, England). 812-3. PMID 12122992 DOI: 10.1039/B200155A  0.772
2000 Sinha S, Mandal B, Chandrasekaran S. Synthesis of ethyl arylacetates by means of Friedel–Crafts reactions of aromatic compounds with ethyl α-chloro-α-(ethylthio)acetate catalysed by ytterbium triflate Tetrahedron Letters. 41: 9109-9112. DOI: 10.1016/S0040-4039(00)01626-9  0.56
2000 Sinha S, Mandal B, Chandrasekaran S. Selective para metalation of unprotected 3-methoxy and 3,5-dimethoxy benzoic acids with n-butyl lithium–potassium tert-butoxide (LIC–KOR): synthesis of 3,5-dimethoxy-4-methyl benzoic acid Tetrahedron Letters. 41: 3157-3160. DOI: 10.1016/S0040-4039(00)00320-8  0.566
1999 Ravikumar KS, Sinha S, Chandrasekaran S. Diastereoselectivity in the Reduction of Acyclic Carbonyl Compounds with Diisopropoxytitanium(III) Tetrahydroborate The Journal of Organic Chemistry. 64: 5841-5844. DOI: 10.1021/Jo9902906  0.506
1999 Sinha S, Ilankumaran P, Chandrasekaran S. The prop-2-ynyloxy carbonyl function (POC): A new amino-protecting group removable from sulfur-containing peptides by ultrasonic irradiation with tetrathiomolybdate under mild and neutral conditions Tetrahedron Letters. 40: 771-774. DOI: 10.1016/S0040-4039(98)02408-3  0.562
1999 Sinha S, Ilankumaran P, Chandrasekaran S. One pot conversion of alcohols to disulfides mediated by benzyltriethylammonium tetrathiomolybdate Tetrahedron. 55: 14769-14776. DOI: 10.1016/S0040-4020(99)00939-4  0.507
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