Hayk Davtyan, Ph.D. - Publications

Affiliations: 
2017- MIND University of California, Irvine, Irvine, CA 
Area:
Alzheimer's disease, Neuroimmunology

61 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Granzotto A, McQuade A, Chadarevian JP, Davtyan H, Sensi SL, Parker I, Blurton-Jones M, Smith I. ER and SOCE Ca signals are not required for directed cell migration in human microglia. Biorxiv : the Preprint Server For Biology. PMID 38293075 DOI: 10.1101/2024.01.18.576126  0.693
2023 Haukedal H, Syshøj Lorenzen S, Winther Westi E, Corsi GI, Gadekar VP, McQuade A, Davtyan H, Doncheva NT, Schmid B, Chandrasekaran A, Seemann SE, Cirera S, Blurton-Jones M, Meyer M, Gorodkin J, et al. Alteration of microglial metabolism and inflammatory profile contributes to neurotoxicity in a hiPSC-derived microglia model of frontotemporal dementia 3. Brain, Behavior, and Immunity. 113: 353-373. PMID 37543250 DOI: 10.1016/j.bbi.2023.07.024  0.738
2023 Chadarevian JP, Davtyan H, Lombroso SI, Bennett FC, Blurton-Jones M. CRISPR generation of CSF1R-G795A human microglia for robust microglia replacement in a chimeric mouse model. Star Protocols. 4: 102490. PMID 37516973 DOI: 10.1016/j.xpro.2023.102490  0.721
2023 Liu Z, Chao J, Wang C, Sun G, Roeth D, Liu W, Chen X, Li L, Tian E, Feng L, Davtyan H, Blurton-Jones M, Kalkum M, Shi Y. Astrocytic response mediated by the CLU risk allele inhibits OPC proliferation and myelination in a human iPSC model. Cell Reports. 42: 112841. PMID 37494190 DOI: 10.1016/j.celrep.2023.112841  0.703
2023 Kim C, Hovakimyan A, Zagorski K, Antonyan T, Petrushina I, Davtyan H, Chailyan G, Hasselmann J, Iba M, Adame A, Rockenstein E, Szabo M, Blurton-Jones M, Cribbs DH, Ghochikyan A, et al. Author Correction: Efficacy and immunogenicity of MultiTEP-based DNA vaccines targeting human α-synuclein: prelude for IND enabling studies. Npj Vaccines. 8: 105. PMID 37460684 DOI: 10.1038/s41541-023-00703-0  0.719
2023 Zagorski K, King O, Hovakimyan A, Petrushina I, Antonyan T, Chailyan G, Ghazaryan M, Hyrc KL, Chadarevian JP, Davtyan H, Blurton-Jones M, Cribbs DH, Agadjanyan MG, Ghochikyan A. Novel Vaccine against Pathological Pyroglutamate-Modified Amyloid Beta for Prevention of Alzheimer's Disease. International Journal of Molecular Sciences. 24. PMID 37372944 DOI: 10.3390/ijms24129797  0.773
2023 McQuade A, Kang YJ, Hasselmann J, Jairaman A, Sotelo A, Coburn M, Shabestari SK, Chadarevian JP, Fote G, Tu CH, Danhash E, Silva J, Martinez E, Cotman C, Prieto GA, ... ... Davtyan H, et al. Author Correction: Gene expression and functional deficits underlie TREM2-knockout microglia responses in human models of Alzheimer's disease. Nature Communications. 14: 1194. PMID 36864071 DOI: 10.1038/s41467-023-36930-1  0.787
2022 Chadarevian JP, Lombroso SI, Peet GC, Hasselmann J, Tu C, Marzan DE, Capocchi J, Purnell FS, Nemec KM, Lahian A, Escobar A, England W, Chaluvadi S, O'Brien CA, Yaqoob F, ... ... Davtyan H, et al. Engineering an inhibitor-resistant human CSF1R variant for microglia replacement. The Journal of Experimental Medicine. 220. PMID 36584406 DOI: 10.1084/jem.20220857  0.724
2022 Kiani Shabestari S, Morabito S, Danhash EP, McQuade A, Sanchez JR, Miyoshi E, Chadarevian JP, Claes C, Coburn MA, Hasselmann J, Hidalgo J, Tran KN, Martini AC, Chang Rothermich W, Pascual J, ... ... Davtyan H, et al. Absence of microglia promotes diverse pathologies and early lethality in Alzheimer's disease mice. Cell Reports. 39: 110961. PMID 35705056 DOI: 10.1016/j.celrep.2022.110961  0.8
2022 Zagorski K, Chailyan G, Hovakimyan A, Antonyan T, Kiani Shabestari S, Petrushina I, Davtyan H, Cribbs DH, Blurton-Jones M, Masliah E, Agadjanyan MG, Ghochikyan A. Immunogenicity of MultiTEP-Platform-Based Recombinant Protein Vaccine, PV-1950R, Targeting Three B-Cell Antigenic Determinants of Pathological α-Synuclein. International Journal of Molecular Sciences. 23. PMID 35682759 DOI: 10.3390/ijms23116080  0.753
2022 Claes C, England WE, Danhash EP, Kiani Shabestari S, Jairaman A, Chadarevian JP, Hasselmann J, Tsai AP, Coburn MA, Sanchez J, Lim TE, Hidalgo JLS, Tu C, Cahalan MD, Lamb BT, ... ... Davtyan H, et al. The P522R protective variant of PLCG2 promotes the expression of antigen presentation genes by human microglia in an Alzheimer's disease mouse model. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 35142046 DOI: 10.1002/alz.12577  0.78
2022 Kim C, Hovakimyan A, Zagorski K, Antonyan T, Petrushina I, Davtyan H, Chailyan G, Hasselmann J, Iba M, Adame A, Rockenstein E, Szabo M, Blurton-Jones M, Cribbs DH, Ghochikyan A, et al. Efficacy and immunogenicity of MultiTEP-based DNA vaccines targeting human α-synuclein: prelude for IND enabling studies. Npj Vaccines. 7: 1. PMID 35013319 DOI: 10.1038/s41541-021-00424-2  0.748
2021 Chen X, Sun G, Tian E, Zhang M, Davtyan H, Beach TG, Reiman EM, Blurton-Jones M, Holtzman DM, Shi Y. Modeling Sporadic Alzheimer's Disease in Human Brain Organoids under Serum Exposure. Advanced Science (Weinheim, Baden-Wurttemberg, Germany). e2101462. PMID 34337898 DOI: 10.1002/advs.202101462  0.771
2021 Claes C, Danhash EP, Hasselmann J, Chadarevian JP, Shabestari SK, England WE, Lim TE, Hidalgo JLS, Spitale RC, Davtyan H, Blurton-Jones M. Plaque-associated human microglia accumulate lipid droplets in a chimeric model of Alzheimer's disease. Molecular Neurodegeneration. 16: 50. PMID 34301296 DOI: 10.1186/s13024-021-00473-0  0.758
2021 Lall D, Lorenzini I, Mota TA, Bell S, Mahan TE, Ulrich JD, Davtyan H, Rexach JE, Muhammad AKMG, Shelest O, Landeros J, Vazquez M, Kim J, Ghaffari L, O'Rourke JG, et al. C9orf72 deficiency promotes microglial-mediated synaptic loss in aging and amyloid accumulation. Neuron. PMID 34133945 DOI: 10.1016/j.neuron.2021.05.020  0.738
2020 McQuade A, Kang YJ, Hasselmann J, Jairaman A, Sotelo A, Coburn M, Shabestari SK, Chadarevian JP, Fote G, Tu CH, Danhash E, Silva J, Martinez E, Cotman C, Prieto GA, ... ... Davtyan H, et al. Gene expression and functional deficits underlie TREM2-knockout microglia responses in human models of Alzheimer's disease. Nature Communications. 11: 5370. PMID 33097708 DOI: 10.1038/s41467-020-19227-5  0.82
2020 Petrushina I, Hovakimyan A, Harahap I, Davtyan H, Antonyan T, Chailyan G, Kazarian K, Antonenko M, Jullienne A, Hamer MM, Obenaus A, King O, Zagorski K, Blurton-Jones M, Cribbs DH, et al. Characterization and preclinical evaluation of the cGMP grade DNA based vaccine, AV-1959D to enter the first-in-human clinical trials. Neurobiology of Disease. 104823. PMID 32119976 DOI: 10.1016/J.Nbd.2020.104823  0.779
2019 Davtyan H, Hovakimyan A, Kiani Shabestari S, Antonyan T, Coburn MA, Zagorski K, Chailyan G, Petrushina I, Svystun O, Danhash E, Petrovsky N, Cribbs DH, Agadjanyan MG, Blurton-Jones M, Ghochikyan A. Testing a MultiTEP-based combination vaccine to reduce Aβ and tau pathology in Tau22/5xFAD bigenic mice. Alzheimer's Research & Therapy. 11: 107. PMID 31847886 DOI: 10.1186/S13195-019-0556-2  0.782
2019 Hovakimyan A, Antonyan T, Shabestari SK, Svystun O, Chailyan G, Coburn MA, Carlen-Jones W, Petrushina I, Chadarevian JP, Zagorski K, Petrovsky N, Cribbs DH, Agadjanyan MG, Ghochikyan A, Davtyan H. A MultiTEP platform-based epitope vaccine targeting the phosphatase activating domain (PAD) of tau: therapeutic efficacy in PS19 mice. Scientific Reports. 9: 15455. PMID 31664089 DOI: 10.1038/S41598-019-51809-2  0.488
2019 Joly-Amado A, Davtyan H, Serraneau K, Jules P, Zitnyar A, Pressman E, Zagorski K, Antonyan T, Hovakimyan A, Paek HJ, Gordon MN, Cribbs DH, Petrovsky N, Agadjanyan MG, Ghochikyan A, et al. Active immunization with tau epitope in a mouse model of tauopathy induced strong antibody response together with improvement in short memory and pSer396-tau pathology. Neurobiology of Disease. 104636. PMID 31629891 DOI: 10.1016/J.Nbd.2019.104636  0.488
2019 Hasselmann J, Coburn MA, England W, Figueroa Velez DX, Kiani Shabestari S, Tu CH, McQuade A, Kolahdouzan M, Echeverria K, Claes C, Nakayama T, Azevedo R, Coufal NG, Han CZ, Cummings BJ, ... Davtyan H, et al. Development of a Chimeric Model to Study and Manipulate Human Microglia In Vivo. Neuron. PMID 31375314 DOI: 10.1016/J.Neuron.2019.07.002  0.77
2019 Rojo R, Raper A, Ozdemir DD, Lefevre L, Grabert K, Wollscheid-Lengeling E, Bradford B, Caruso M, Gazova I, Sánchez A, Lisowski ZM, Alves J, Molina-Gonzalez I, Davtyan H, Lodge RJ, et al. Deletion of a Csf1r enhancer selectively impacts CSF1R expression and development of tissue macrophage populations. Nature Communications. 10: 3215. PMID 31324781 DOI: 10.1038/S41467-019-11053-8  0.726
2019 Faal T, Phan DTT, Davtyan H, Scarfone VM, Varady E, Blurton-Jones M, Hughes CCW, Inlay MA. Induction of Mesoderm and Neural Crest-Derived Pericytes from Human Pluripotent Stem Cells to Study Blood-Brain Barrier Interactions. Stem Cell Reports. PMID 30745035 DOI: 10.1016/J.Stemcr.2019.01.005  0.756
2018 McQuade A, Coburn M, Tu CH, Hasselmann J, Davtyan H, Blurton-Jones M. Development and validation of a simplified method to generate human microglia from pluripotent stem cells. Molecular Neurodegeneration. 13: 67. PMID 30577865 DOI: 10.1186/S13024-018-0297-X  0.755
2017 Davtyan H, Zagorski K, Petrushina I, Kazarian K, Goldberg NRS, Petrosyan J, Blurton-Jones M, Masliah E, Cribbs DH, Agadjanyan MG, Ghochikyan A. MultiTEP platform-based DNA vaccines for alpha-synucleinopathies: preclinical evaluation of immunogenicity and therapeutic potency. Neurobiology of Aging. PMID 28870518 DOI: 10.1016/J.Neurobiolaging.2017.08.006  0.765
2017 Agadjanyan MG, Zagorski K, Petrushina I, Davtyan H, Kazarian K, Antonenko M, Davis J, Bon C, Blurton-Jones M, Cribbs DH, Ghochikyan A. Humanized monoclonal antibody armanezumab specific to N-terminus of pathological tau: characterization and therapeutic potency. Molecular Neurodegeneration. 12: 33. PMID 28472993 DOI: 10.1186/S13024-017-0172-1  0.76
2017 Davtyan H, Chen WW, Zagorski K, Davis J, Petrushina I, Kazarian K, Cribbs DH, Agadjanyan MG, Blurton-Jones M, Ghochikyan A. MultiTEP platform-based DNA epitope vaccine targeting N-terminus of tau induces strong immune responses and reduces tau pathology in THY-Tau22 mice. Vaccine. PMID 28320590 DOI: 10.1016/J.Vaccine.2017.03.020  0.792
2017 Goldberg NR, Marsh SE, Ochaba J, Shelley BC, Davtyan H, Thompson LM, Steffan JS, Svendsen CN, Blurton-Jones M. Human Neural Progenitor Transplantation Rescues Behavior and Reduces α-Synuclein in a Transgenic Model of Dementia with Lewy Bodies. Stem Cells Translational Medicine. PMID 28225193 DOI: 10.1002/Sctm.16-0362  0.745
2017 Petrushina I, Davtyan H, Hovakimyan A, Davtyan A, Passos GF, Cribbs DH, Ghochikyan A, Agadjanyan MG. Comparison of Efficacy of Preventive and Therapeutic Vaccines Targeting the N Terminus of β-Amyloid in an Animal Model of Alzheimer's Disease. Molecular Therapy : the Journal of the American Society of Gene Therapy. 25: 153-164. PMID 28129111 DOI: 10.1016/J.Ymthe.2016.10.002  0.517
2016 Davtyan H, Zagorski K, Rajapaksha H, Hovakimyan A, Davtyan A, Petrushina I, Kazarian K, Cribbs DH, Petrovsky N, Agadjanyan MG, Ghochikyan A. Alzheimer's disease Advax(CpG)- adjuvanted MultiTEP-based dual and single vaccines induce high-titer antibodies against various forms of tau and Aβ pathological molecules. Scientific Reports. 6: 28912. PMID 27363809 DOI: 10.1038/Srep28912  0.426
2016 Marsh SE, Abud EM, Lakatos A, Karimzadeh A, Yeung ST, Davtyan H, Fote GM, Lau L, Weinger JG, Lane TE, Inlay MA, Poon WW, Blurton-Jones M. The adaptive immune system restrains Alzheimer's disease pathogenesis by modulating microglial function. Proceedings of the National Academy of Sciences of the United States of America. PMID 26884167 DOI: 10.1073/Pnas.1525466113  0.808
2016 Marsh SE, Karimzadeh A, Abud EM, Lakatos A, Yeung ST, Davtyan H, Fote G, Lau L, Weinger JG, Lane TE, Poon WW, Inlay MA, Blurton-Jones M. P1-158: The Adaptive Immune System Critically Regulates Alzheimer’s Disease Pathogenesis by Modulating Microglial Function Alzheimer's & Dementia. 12: P463-P464. DOI: 10.1016/J.Jalz.2016.06.906  0.764
2016 Ghochikyan A, Zagorski K, Kazarian K, Davtyan H, Petrushina I, Davis J, Chen WW, Antonenko M, Blurton-Jones M, Cribbs DH, Agadjanyan MG. O2-13-02: Humanized Mab, Armanezumab Targeting N-Terminus of Pathological Tau: Characterization and Therapeutic Potency Alzheimer's & Dementia. 12: P260-P260. DOI: 10.1016/J.Jalz.2016.06.467  0.726
2016 Davtyan H, Chen WW, Zagorski K, Davis J, Petrushina I, Cribbs DH, Agadjanyan MG, Blurton-Jones M, Ghochikyan A. P4-037: The First Multitep-Based DNA Vaccine Targeting n-Terminus of Pathological TAU Induces Strong Immune Responses and Reduces TAU Pathology in TAU Transgenic Mice Alzheimer's & Dementia. 12: P1029-P1029. DOI: 10.1016/J.Jalz.2016.06.2126  0.771
2014 Davtyan H, Ghochikyan A, Hovakimyan A, Davtyan A, Cadagan R, Marleau AM, Albrecht RA, García-Sastre A, Agadjanyan MG. A dual vaccine against influenza & Alzheimer's disease failed to enhance anti-β-amyloid antibody responses in mice with pre-existing virus specific memory. Journal of Neuroimmunology. 277: 77-84. PMID 25455094 DOI: 10.1016/J.Jneuroim.2014.10.002  0.414
2014 Ghochikyan A, Pichugin A, Bagaev A, Davtyan A, Hovakimyan A, Tukhvatulin A, Davtyan H, Shcheblyakov D, Logunov D, Chulkina M, Savilova A, Trofimov D, Nelson EL, Agadjanyan MG, Ataullakhanov RI. Targeting TLR-4 with a novel pharmaceutical grade plant derived agonist, Immunomax®, as a therapeutic strategy for metastatic breast cancer. Journal of Translational Medicine. 12: 322. PMID 25432242 DOI: 10.1186/S12967-014-0322-Y  0.327
2014 Selenica ML, Davtyan H, Housley SB, Blair LJ, Gillies A, Nordhues BA, Zhang B, Liu J, Gestwicki JE, Lee DC, Gordon MN, Morgan D, Dickey CA. Epitope analysis following active immunization with tau proteins reveals immunogens implicated in tau pathogenesis. Journal of Neuroinflammation. 11: 152. PMID 25183004 DOI: 10.1186/S12974-014-0152-0  0.47
2014 Davtyan H, Hovakimyan A, Zagorski K, Davtyan A, Petrushina I, Agdashian D, Murthy V, Cribbs DH, Agadjanyan MG, Ghochikyan A. BTX AgilePulse(TM) system is an effective electroporation device for intramuscular and intradermal delivery of DNA vaccine. Current Gene Therapy. 14: 190-9. PMID 24867066 DOI: 10.2174/1566523214666140522121427  0.378
2014 Davtyan H, Petrushina I, Ghochikyan A. Immunotherapy for Alzheimer's disease: DNA- and protein-based epitope vaccines. Methods in Molecular Biology (Clifton, N.J.). 1143: 259-81. PMID 24715293 DOI: 10.1007/978-1-4939-0410-5_16  0.478
2014 Davtyan H, Ghochikyan A, Petrushina I, Hovakimyan A, Davtyan A, Cribbs DH, Agadjanyan MG. The MultiTEP platform-based Alzheimer's disease epitope vaccine activates a broad repertoire of T helper cells in nonhuman primates. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 10: 271-83. PMID 24560029 DOI: 10.1016/J.Jalz.2013.12.003  0.442
2014 Davtyan H, Bacon A, Petrushina I, Zagorski K, Cribbs DH, Ghochikyan A, Agadjanyan MG. Immunogenicity of DNA- and recombinant protein-based Alzheimer disease epitope vaccines. Human Vaccines & Immunotherapeutics. 10: 1248-55. PMID 24525778 DOI: 10.4161/Hv.27882  0.497
2014 Davtyan H, Ghochikyan A, Hovakimyan A, Petrushina I, Yu J, Flyer D, Madsen PJ, Pedersen LO, Cribbs DH, Agadjanyan MG. Immunostimulant patches containing Escherichia coli LT enhance immune responses to DNA- and recombinant protein-based Alzheimer's disease vaccines. Journal of Neuroimmunology. 268: 50-7. PMID 24507620 DOI: 10.1016/J.Jneuroim.2014.01.002  0.457
2014 Ghochikyan A, Petrushina I, Davtyan H, Hovakimyan A, Saing T, Davtyan A, Cribbs DH, Agadjanyan MG. Immunogenicity of epitope vaccines targeting different B cell antigenic determinants of human α-synuclein: feasibility study. Neuroscience Letters. 560: 86-91. PMID 24361548 DOI: 10.1016/J.Neulet.2013.12.028  0.462
2014 Evans CF, Davtyan H, Petrushina I, Hovakimyan A, Davtyan A, Hannaman D, Cribbs DH, Agadjanyan MG, Ghochikyan A. Epitope-based DNA vaccine for Alzheimer's disease: translational study in macaques. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 10: 284-95. PMID 23916838 DOI: 10.1016/J.Jalz.2013.04.505  0.471
2013 Cohen RM, Rezai-Zadeh K, Weitz TM, Rentsendorj A, Gate D, Spivak I, Bholat Y, Vasilevko V, Glabe CG, Breunig JJ, Rakic P, Davtyan H, Agadjanyan MG, Kepe V, Barrio JR, et al. A transgenic Alzheimer rat with plaques, tau pathology, behavioral impairment, oligomeric aβ, and frank neuronal loss. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 6245-56. PMID 23575824 DOI: 10.1523/Jneurosci.3672-12.2013  0.446
2013 Davtyan H, Ghochikyan A, Petrushina I, Hovakimyan A, Davtyan A, Poghosyan A, Marleau AM, Movsesyan N, Kiyatkin A, Rasool S, Larsen AK, Madsen PJ, Wegener KM, Ditlevsen DK, Cribbs DH, et al. Immunogenicity, efficacy, safety, and mechanism of action of epitope vaccine (Lu AF20513) for Alzheimer's disease: prelude to a clinical trial. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 4923-34. PMID 23486963 DOI: 10.1523/Jneurosci.4672-12.2013  0.518
2013 Ghochikyan A, Davtyan H, Petrushina I, Hovakimyan A, Movsesyan N, Davtyan A, Kiyatkin A, Cribbs DH, Agadjanyan MG. Refinement of a DNA based Alzheimer's disease epitope vaccine in rabbits. Human Vaccines & Immunotherapeutics. 9: 1002-10. PMID 23399748 DOI: 10.4161/Hv.23875  0.467
2013 Selenica M, Housley S, Blair L, Davtyan H, Sanneh A, Mouse T, Lee D, Gordon MN, Morgan D, Dickey C. P2-415: Immunotherapy targeting human wild type and P301L tau results in an immune response and changes in tau levels in an rTG4510 mouse model Alzheimer's & Dementia. 9: P509-P510. DOI: 10.1016/J.Jalz.2013.05.1065  0.408
2012 Davtyan H, Ghochikyan A, Movsesyan N, Ellefsen B, Petrushina I, Cribbs DH, Hannaman D, Evans CF, Agadjanyan MG. Delivery of a DNA vaccine for Alzheimer's disease by electroporation versus gene gun generates potent and similar immune responses. Neuro-Degenerative Diseases. 10: 261-4. PMID 22301697 DOI: 10.1159/000333359  0.475
2012 Davtyan H, Ghochikyan A, Petrushina I, Hovakimyan A, Movsesyan N, Kiyatkin A, Hannaman D, Evans CF, Cribbs D, Agadjanyan M. P1-306: Translational study: Refinement of DNA-based Alzheimer's disease (AD) epitope vaccine in rabbits Alzheimer's & Dementia. 8: P211-P211. DOI: 10.1016/J.Jalz.2012.05.587  0.454
2011 Davtyan H, Ghochikyan A, Cadagan R, Zamarin D, Petrushina I, Movsesyan N, Martinez-Sobrido L, Albrecht RA, García-Sastre A, Agadjanyan MG. The immunological potency and therapeutic potential of a prototype dual vaccine against influenza and Alzheimer's disease. Journal of Translational Medicine. 9: 127. PMID 21806809 DOI: 10.1186/1479-5876-9-127  0.447
2011 Mkrtichyan M, Ghochikyan A, Davtyan H, Movsesyan N, Loukinov D, Lobanenkov V, Cribbs DH, Laust AK, Nelson EL, Agadjanyan MG. Cancer-testis antigen, BORIS based vaccine delivered by dendritic cells is extremely effective against a very aggressive and highly metastatic mouse mammary carcinoma. Cellular Immunology. 270: 188-97. PMID 21641588 DOI: 10.1016/J.Cellimm.2011.05.007  0.359
2010 Movsesyan N, Davtyan H, Mkrtichyan M, Petrushina I, Tiraturyan T, Ross T, Agadjanyan MG, Ghochikyan A, Cribbs DH. Low concentrations of anti-Aβ antibodies generated in Tg2576 mice by DNA epitope vaccine fused with 3C3d molecular adjuvant do not affect AD pathology. Human Gene Therapy. 21: 1569-76. PMID 20528468 DOI: 10.1089/Hum.2009.219  0.472
2010 Davtyan H, Mkrtichyan M, Movsesyan N, Petrushina I, Mamikonyan G, Cribbs DH, Agadjanyan MG, Ghochikyan A. DNA prime-protein boost increased the titer, avidity and persistence of anti-Abeta antibodies in wild-type mice. Gene Therapy. 17: 261-71. PMID 19865176 DOI: 10.1038/Gt.2009.140  0.44
2010 Mkrtichyan M, Ghochikyan A, Loukinov D, Movsesyan N, Davtyan H, Laust AK, Lobanenkov V, Nelson EL, Agadjanyan M. Abstract LB-319: A novel cancer-testis antigen, BORIS-based vaccine delivered by dendritic cells is effective against metastatic disease Immunology. 70. DOI: 10.1158/1538-7445.Am10-Lb-319  0.357
2010 Davtyan H, Ghochikyan A, Mkrtichyan M, Movsesyan N, Petrushina I, Cribbs DH, Agadjanyan MG. P3-468: Exploiting prime-boost regimen and various delivery strategies to improve Alzhaimer's disease DNA vaccine efficacy Alzheimer's & Dementia. 6: S591-S591. DOI: 10.1016/J.Jalz.2010.05.2011  0.35
2009 Ghochikyan A, Davtyan H, Movsesyan N, Mkrtichyan M, Petrushina I, Cribbs DH, Agadjanyan MG. O2-05-02: Induction of rapid and robust anti-Aβ antibody production by reactivation of pre-existing memory Th cells generated from conventional vaccines Alzheimer's & Dementia. 5: P112-P113. DOI: 10.1016/J.Jalz.2009.05.353  0.349
2008 Movsesyan N, Ghochikyan A, Mkrtichyan M, Petrushina I, Davtyan H, Olkhanud PB, Head E, Biragyn A, Cribbs DH, Agadjanyan MG. Reducing AD-like pathology in 3xTg-AD mouse model by DNA epitope vaccine - a novel immunotherapeutic strategy. Plos One. 3: e2124. PMID 18461171 DOI: 10.1371/Journal.Pone.0002124  0.637
2008 Mkrtichyan M, Ghochikyan A, Loukinov D, Davtyan H, Ichim TE, Cribbs DH, Lobanenkov VV, Agadjanyan MG. DNA, but not protein vaccine based on mutated BORIS antigen significantly inhibits tumor growth and prolongs the survival of mice. Gene Therapy. 15: 61-4. PMID 17972923 DOI: 10.1038/Sj.Gt.3303044  0.381
2008 Ghochikyan A, Martinez L, Movsesyan N, Mkrtichyan M, Petrushina I, Davtyan H, Cribbs DH, Garcı́a-Sastre A, Agadjanyan MG. P2-298: The novel strategy for generation of effective and safe Alzheimer's disease vaccine based on conventional influenza virus vaccine modified to express Aβ1-11 Alzheimers & Dementia. 4. DOI: 10.1016/J.Jalz.2008.05.1374  0.4
2007 Petrushina I, Ghochikyan A, Mktrichyan M, Mamikonyan G, Movsesyan N, Davtyan H, Patel A, Head E, Cribbs DH, Agadjanyan MG. Alzheimer's disease peptide epitope vaccine reduces insoluble but not soluble/oligomeric Abeta species in amyloid precursor protein transgenic mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 12721-31. PMID 18003852 DOI: 10.1523/Jneurosci.3201-07.2007  0.622
Show low-probability matches.