| Year |
Citation |
Score |
| 2024 |
Milioto C, Carcolé M, Giblin A, Coneys R, Attrebi O, Ahmed M, Harris SS, Lee BI, Yang M, Ellingford RA, Nirujogi RS, Biggs D, Salomonsson S, Zanovello M, de Oliveira P, ... ... Coyne AN, et al. PolyGR and polyPR knock-in mice reveal a conserved neuroprotective extracellular matrix signature in C9orf72 ALS/FTD neurons. Nature Neuroscience. PMID 38424324 DOI: 10.1038/s41593-024-01589-4 |
0.311 |
|
| 2023 |
Rothstein JD, Warlick C, Coyne AN. Highly variable molecular signatures of TDP-43 loss of function are associated with nuclear pore complex injury in a population study of sporadic ALS patient iPSNs. Biorxiv : the Preprint Server For Biology. PMID 38168312 DOI: 10.1101/2023.12.12.571299 |
0.359 |
|
| 2023 |
Rothstein JD, Baskerville V, Rapuri S, Mehlhop E, Jafar-Nejad P, Rigo F, Bennett F, Mizielinska S, Isaacs A, Coyne AN. GC targeting antisense oligonucleotides potently mitigate TDP-43 dysfunction in human C9orf72 ALS/FTD induced pluripotent stem cell derived neurons. Acta Neuropathologica. 147: 1. PMID 38019311 DOI: 10.1007/s00401-023-02652-3 |
0.4 |
|
| 2023 |
Baskerville V, Rapuri S, Mehlhop E, Coyne AN. SUN1 facilitates CHMP7 nuclear influx and injury cascades in sporadic amyotrophic lateral sclerosis. Brain : a Journal of Neurology. PMID 37639327 DOI: 10.1093/brain/awad291 |
0.359 |
|
| 2021 |
Li J, Lim RG, Kaye JA, Dardov V, Coyne AN, Wu J, Milani P, Cheng A, Thompson TG, Ornelas L, Frank A, Adam M, Banuelos MG, Casale M, et al. An integrated multi-omic analysis of iPSC-derived motor neurons from C9ORF72 ALS patients. Iscience. 24: 103221. PMID 34746695 DOI: 10.1016/j.isci.2021.103221 |
0.393 |
|
| 2021 |
Coyne AN, Baskerville V, Zaepfel BL, Dickson DW, Rigo F, Bennett F, Lusk CP, Rothstein JD. Nuclear accumulation of CHMP7 initiates nuclear pore complex injury and subsequent TDP-43 dysfunction in sporadic and familial ALS. Science Translational Medicine. 13. PMID 34321318 DOI: 10.1126/scitranslmed.abe1923 |
0.453 |
|
| 2021 |
Coyne AN, Rothstein JD. The ESCRT-III protein VPS4, but not CHMP4B or CHMP2B, is pathologically increased in familial and sporadic ALS neuronal nuclei. Acta Neuropathologica Communications. 9: 127. PMID 34281622 DOI: 10.1186/s40478-021-01228-0 |
0.376 |
|
| 2021 |
Zaepfel BL, Zhang Z, Maulding K, Coyne AN, Cheng W, Hayes LR, Lloyd TE, Sun S, Rothstein JD. UPF1 reduces C9orf72 HRE-induced neurotoxicity in the absence of nonsense-mediated decay dysfunction. Cell Reports. 34: 108925. PMID 33789100 DOI: 10.1016/j.celrep.2021.108925 |
0.514 |
|
| 2021 |
Coyne AN, Rothstein JD. Nuclear lamina invaginations are not a pathological feature of C9orf72 ALS/FTD. Acta Neuropathologica Communications. 9: 45. PMID 33741069 DOI: 10.1186/s40478-021-01150-5 |
0.426 |
|
| 2020 |
Coyne AN, Zaepfel BL, Hayes L, Fitchman B, Salzberg Y, Luo EC, Bowen K, Trost H, Aigner S, Rigo F, Yeo GW, Harel A, Svendsen CN, Sareen D, Rothstein JD. GC Repeat RNA Initiates a POM121-Mediated Reduction in Specific Nucleoporins in C9orf72 ALS/FTD. Neuron. PMID 32673563 DOI: 10.1016/J.Neuron.2020.06.027 |
0.506 |
|
| 2019 |
Nguyen L, Montrasio F, Pattamatta A, Tusi SK, Bardhi O, Meyer KD, Hayes L, Nakamura K, Banez-Coronel M, Coyne A, Guo S, Laboissonniere LA, Gu Y, Narayanan S, Smith B, et al. Antibody Therapy Targeting RAN Proteins Rescues C9 ALS/FTD Phenotypes in C9orf72 Mouse Model. Neuron. PMID 31831332 DOI: 10.1016/J.Neuron.2019.11.007 |
0.406 |
|
| 2019 |
Cheng W, Wang S, Zhang Z, Morgens DW, Hayes LR, Lee S, Portz B, Xie Y, Nguyen BV, Haney MS, Yan S, Dong D, Coyne AN, Yang J, Xian F, et al. CRISPR-Cas9 Screens Identify the RNA Helicase DDX3X as a Repressor of C9ORF72 (GGGGCC)n Repeat-Associated Non-AUG Translation. Neuron. PMID 31587919 DOI: 10.1016/J.Neuron.2019.09.003 |
0.466 |
|
| 2019 |
Eftekharzadeh B, Daigle JG, Kapinos LE, Coyne A, Schiantarelli J, Carlomagno Y, Cook C, Miller SJ, Dujardin S, Amaral AS, Grima JC, Bennett RE, Tepper K, DeTure M, Vanderburg CR, et al. Tau Protein Disrupts Nucleocytoplasmic Transport in Alzheimer's Disease. Neuron. 101: 349. PMID 30653936 DOI: 10.1016/J.Neuron.2018.12.031 |
0.336 |
|
| 2018 |
Eftekharzadeh B, Daigle JG, Kapinos LE, Coyne A, Schiantarelli J, Carlomagno Y, Cook C, Miller SJ, Dujardin S, Amaral AS, Grima JC, Bennett RE, Tepper K, DeTure M, Vanderburgh CR, et al. Tau Protein Disrupts Nucleocytoplasmic Transport in Alzheimer's Disease. Neuron. 99: 925-940.e7. PMID 30189209 DOI: 10.1016/J.Neuron.2018.07.039 |
0.334 |
|
| 2018 |
Zhang K, Coyne AN, Lloyd TE. Drosophila models of amyotrophic lateral sclerosis with defects in RNA metabolism. Brain Research. PMID 29752901 DOI: 10.1016/J.Brainres.2018.04.043 |
0.455 |
|
| 2018 |
Zhang K, Daigle JG, Cunningham KM, Coyne AN, Ruan K, Grima JC, Bowen KE, Wadhwa H, Yang P, Rigo F, Taylor JP, Gitler AD, Rothstein JD, Lloyd TE. Stress Granule Assembly Disrupts Nucleocytoplasmic Transport. Cell. PMID 29628143 DOI: 10.1016/J.Cell.2018.03.025 |
0.346 |
|
| 2017 |
Liu G, Coyne AN, Pei F, Vaughan S, Chaung M, Zarnescu DC, Buchan JR. Endocytosis regulates TDP-43 toxicity and turnover. Nature Communications. 8: 2092. PMID 29233983 DOI: 10.1038/S41467-017-02017-X |
0.674 |
|
| 2017 |
Coyne AN, Lorenzini I, Chou CC, Torvund M, Rogers RS, Starr A, Zaepfel BL, Levy J, Johannesmeyer J, Schwartz JC, Nishimune H, Zinsmaier K, Rossoll W, Sattler R, Zarnescu DC. Post-transcriptional Inhibition of Hsc70-4/HSPA8 Expression Leads to Synaptic Vesicle Cycling Defects in Multiple Models of ALS. Cell Reports. 21: 110-125. PMID 28978466 DOI: 10.1016/J.Celrep.2017.09.028 |
0.671 |
|
| 2017 |
Coyne AN, Zaepfel BL, Zarnescu DC. Failure to Deliver and Translate-New Insights into RNA Dysregulation in ALS. Frontiers in Cellular Neuroscience. 11: 243. PMID 28860970 DOI: 10.3389/fncel.2017.00243 |
0.67 |
|
| 2016 |
Coyne AN, Zarnescu DC. A Helping Hand: RNA-Binding Proteins Guide Gene-Binding Choices by Cohesin Complexes. Plos Genetics. 12: e1006419. PMID 27855157 DOI: 10.1371/journal.pgen.1006419 |
0.589 |
|
| 2015 |
Coyne AN, Yamada SB, Siddegowda BB, Estes PS, Zaepfel BL, Johannesmeyer JS, Lockwood DB, Pham LT, Hart MP, Cassel JA, Freibaum B, Boehringer AV, Taylor JP, Reitz AB, Gitler AD, et al. Fragile X protein mitigates TDP-43 toxicity by remodeling RNA granules and restoring translation. Human Molecular Genetics. PMID 26385636 DOI: 10.1093/Hmg/Ddv389 |
0.696 |
|
| 2014 |
Coyne AN, Siddegowda BB, Estes PS, Johannesmeyer J, Kovalik T, Daniel SG, Pearson A, Bowser R, Zarnescu DC. Futsch/MAP1B mRNA is a translational target of TDP-43 and is neuroprotective in a Drosophila model of amyotrophic lateral sclerosis. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 15962-74. PMID 25429138 DOI: 10.1523/Jneurosci.2526-14.2014 |
0.673 |
|
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