David C. Parker - Publications

Affiliations: 
MMI Oregon Health and Science University, Portland, OR 

50 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2017 Polesso F, Sarker M, Anderson A, Parker DC, Murray SE. Constitutive expression of NF-κB inducing kinase in regulatory T cells impairs suppressive function and promotes instability and pro-inflammatory cytokine production. Scientific Reports. 7: 14779. PMID 29116141 DOI: 10.1038/S41598-017-14965-X  0.516
2017 Gardell JL, Parker DC. Despite disorganized synapse structure, Th2 cells maintain directional delivery of CD40L to antigen-presenting B cells. Plos One. 12: e0186573. PMID 29023539 DOI: 10.1371/Journal.Pone.0186573  0.624
2016 Gardell JL, Parker DC. CD40L is transferred to antigen-presenting B cells during delivery of T-cell help. European Journal of Immunology. PMID 27753080 DOI: 10.1002/Eji.201646504  0.609
2015 Moran A, Polesso F, Sarker M, Parker D, Murray SE, Weinberg A. Finding the right balance: aOX40 immunotherapy enhances effector T cell function without impairing regulatory T cells intrinsic suppressive capacity in mouse tumor models Journal For Immunotherapy of Cancer. 3: 77. DOI: 10.1186/2051-1426-3-S2-P77  0.601
2014 Thauland TJ, Koguchi Y, Dustin ML, Parker DC. CD28-CD80 interactions control regulatory T cell motility and immunological synapse formation. Journal of Immunology (Baltimore, Md. : 1950). 193: 5894-903. PMID 25355918 DOI: 10.4049/Jimmunol.1401752  0.547
2013 Rowe AM, Murray SE, Raué HP, Koguchi Y, Slifka MK, Parker DC. A cell-intrinsic requirement for NF-κB-inducing kinase in CD4 and CD8 T cell memory. Journal of Immunology (Baltimore, Md. : 1950). 191: 3663-72. PMID 24006459 DOI: 10.4049/Jimmunol.1301328  0.572
2013 Parker DC. The carrier effect and T cell/B cell cooperation in the antibody response Journal of Immunology. 191: 2025-2027. PMID 23964101 DOI: 10.4049/Jimmunol.1301692  0.472
2013 Murray SE, Toren KG, Parker DC. Peripheral CD4(+) T-cell tolerance is induced in vivo by rare antigen-bearing B cells in follicular, marginal zone, and B-1 subsets. European Journal of Immunology. 43: 1818-27. PMID 23532986 DOI: 10.1002/Eji.201242784  0.588
2013 Dillon TJ, Takahashi M, Li Y, Tavisala S, Murray SE, Moran AE, Parker DC, Stork PJ. B-Raf is required for positive selection and survival of DP cells, but not for negative selection of SP cells. International Immunology. 25: 259-69. PMID 23334952 DOI: 10.1093/Intimm/Dxs104  0.44
2012 Koguchi Y, Buenafe AC, Thauland TJ, Gardell JL, Bivins-Smith ER, Jacoby DB, Slifka MK, Parker DC. Preformed CD40L is stored in Th1, Th2, Th17, and T follicular helper cells as well as CD4+ 8- thymocytes and invariant NKT cells but not in Treg cells. Plos One. 7: e31296. PMID 22363608 DOI: 10.1371/Journal.Pone.0031296  0.622
2011 Murray SE, Polesso F, Rowe AM, Basak S, Koguchi Y, Toren KG, Hoffmann A, Parker DC. NF-κB–inducing kinase plays an essential T cell–intrinsic role in graft-versus-host disease and lethal autoimmunity in mice. The Journal of Clinical Investigation. 121: 4775-86. PMID 22045568 DOI: 10.1172/Jci44943  0.574
2011 Koguchi Y, Gardell JL, Thauland TJ, Parker DC. Cyclosporine-resistant, Rab27a-independent mobilization of intracellular preformed CD40 ligand mediates antigen-specific T cell help in vitro Journal of Immunology. 187: 626-634. PMID 21677130 DOI: 10.4049/Jimmunol.1004083  0.619
2010 Thauland TJ, Parker DC. Diversity in immunological synapse structure Immunology. 131: 466-472. PMID 21039474 DOI: 10.1111/J.1365-2567.2010.03366.X  0.602
2010 Doherty M, Osborne DG, Browning DL, Parker DC, Wetzel SA. Anergic CD4+ T cells form mature immunological synapses with enhanced accumulation of c-Cbl and Cbl-b. Journal of Immunology (Baltimore, Md. : 1950). 184: 3598-608. PMID 20207996 DOI: 10.4049/Jimmunol.0902285  0.772
2008 Thauland TJ, Koguchi Y, Wetzel SA, Dustin ML, Parker DC. Th1 and Th2 cells form morphologically distinct immunological synapses. Journal of Immunology (Baltimore, Md. : 1950). 181: 393-9. PMID 18566405 DOI: 10.4049/Jimmunol.181.1.393  0.757
2007 Koguchi Y, Thauland TJ, Slifka MK, Parker DC. Preformed CD40 ligand exists in secretory lysosomes in effector and memory CD4+ T cells and is quickly expressed on the cell surface in an antigen-specific manner Blood. 110: 2520-2527. PMID 17595332 DOI: 10.1182/Blood-2007-03-081299  0.596
2007 Williams CA, Murray SE, Weinberg AD, Parker DC. OX40-mediated differentiation to effector function requires IL-2 receptor signaling but not CD28, CD40, IL-12Rbeta2, or T-bet. Journal of Immunology (Baltimore, Md. : 1950). 178: 7694-702. PMID 17548606 DOI: 10.4049/Jimmunol.178.12.7694  0.566
2006 Tian Q, Beardall M, Xu Y, Li J, Parker DC, Casanova N, Bakke AC, Chen C. B cells expressing a natural polyreactive autoantibody have a distinct phenotype and are overrepresented in immunoglobulin heavy chain transgenic mice. Journal of Immunology (Baltimore, Md. : 1950). 177: 2412-22. PMID 16888003 DOI: 10.4049/Jimmunol.177.4.2412  0.396
2006 Dullforce PA, Seitz GW, Garman KL, Michael JA, Crespo SM, Fleischman RJ, Planck SR, Parker DC, Rosenbaum JT. Antigen-specific accumulation of naïve, memory and effector CD4 T cells during anterior uveitis monitored by intravital microscopy Cellular Immunology. 239: 49-60. PMID 16712823 DOI: 10.1016/J.Cellimm.2006.03.005  0.616
2006 Huddleston CA, Weinberg AD, Parker DC. OX40 (CD134) engagement drives differentiation of CD4+ T cells to effector cells European Journal of Immunology. 36: 1093-1103. PMID 16541471 DOI: 10.1002/Eji.200535637  0.606
2006 Wetzel SA, Parker DC. MHC transfer from APC to T cells following antigen recognition. Critical Reviews in Immunology. 26: 1-21. PMID 16472066 DOI: 10.1615/Critrevimmunol.V26.I1.10  0.794
2005 Dillon TJ, Carey KD, Wetzel SA, Parker DC, Stork PJ. Regulation of the small GTPase Rap1 and extracellular signal-regulated kinases by the costimulatory molecule CTLA-4. Molecular and Cellular Biology. 25: 4117-28. PMID 15870282 DOI: 10.1128/Mcb.25.10.4117-4128.2005  0.779
2005 Wetzel SA, McKeithan TW, Parker DC. Peptide-specific intercellular transfer of MHC class II to CD4+ T cells directly from the immunological synapse upon cellular dissociation. Journal of Immunology (Baltimore, Md. : 1950). 174: 80-9. PMID 15611230 DOI: 10.4049/Jimmunol.174.1.80  0.778
2004 Lathrop SK, Huddleston CA, Dullforce PA, Montfort MJ, Weinberg AD, Parker DC. A signal through OX40 (CD134) allows anergic, autoreactive T cells to acquire effector cell functions. Journal of Immunology (Baltimore, Md. : 1950). 172: 6735-43. PMID 15153490 DOI: 10.4049/Jimmunol.172.11.6735  0.602
2003 Dillon TJ, Karpitski V, Wetzel SA, Parker DC, Shaw AS, Stork PJ. Ectopic B-Raf expression enhances extracellular signal-regulated kinase (ERK) signaling in T cells and prevents antigen-presenting cell-induced anergy. The Journal of Biological Chemistry. 278: 35940-9. PMID 12855697 DOI: 10.1074/Jbc.M301506200  0.773
2003 Becker MD, Planck SR, Crespo S, Garman K, Fleischman RJ, Dullforce P, Seitz GW, Martin TM, Parker DC, Rosenbaum JT. Immunohistology of antigen-presenting cells in vivo: a novel method for serial observation of fluorescently labeled cells. Investigative Ophthalmology & Visual Science. 44: 2004-9. PMID 12714636 DOI: 10.1167/Iovs.02-0560  0.432
2002 Wetzel SA, McKeithan TW, Parker DC. Live-cell dynamics and the role of costimulation in immunological synapse formation. Journal of Immunology (Baltimore, Md. : 1950). 169: 6092-101. PMID 12444111 DOI: 10.4049/Jimmunol.169.11.6092  0.788
2000 Evans DE, Munks MW, Purkerson JM, Parker DC. Resting B lymphocytes as APC for naive T lymphocytes: dependence on CD40 ligand/CD40. Journal of Immunology (Baltimore, Md. : 1950). 164: 688-97. PMID 10623811 DOI: 10.4049/Jimmunol.164.2.688  0.61
1996 Rossini AA, Parker DC, Phillips NE, Durie FH, Noelle RJ, Mordes JP, Greiner DL. Induction of immunological tolerance to islet allografts. Cell Transplantation. 5: 49-52. PMID 8665076 DOI: 10.1016/0963-6897(95)02010-1  0.499
1995 Kozono H, Parker D, White J, Marrack P, Kappler J. Multiple binding sites for bacterial superantigens on soluble class II MHC molecules. Immunity. 3: 187-96. PMID 7648392 DOI: 10.1016/1074-7613(95)90088-8  0.37
1995 Parker DC, Greiner DL, Phillips NE, Appel MC, Steele AW, Durie FH, Noelle RJ, Mordes JP, Rossini AA. Survival of mouse pancreatic islet allografts in recipients treated with allogeneic small lymphocytes and antibody to CD40 ligand. Proceedings of the National Academy of Sciences of the United States of America. 92: 9560-4. PMID 7568172 DOI: 10.1073/Pnas.92.21.9560  0.434
1995 Wortis HH, Teutsch M, Higer M, Zheng J, Parker DC. B-cell activation by crosslinking of surface IgM or ligation of CD40 involves alternative signal pathways and results in different B-cell phenotypes Proceedings of the National Academy of Sciences of the United States of America. 92: 3348-3352. PMID 7536930 DOI: 10.1073/Pnas.92.8.3348  0.562
1993 Parker DC. T cell-dependent B cell activation Annual Review of Immunology. 11: 331-360. PMID 8476565 DOI: 10.1146/Annurev.Iy.11.040193.001555  0.609
1993 Lalmanach-Girard AC, Chiles TC, Parker DC, Rothstein TL. T cell-dependent induction of NF-κB in B cells Journal of Experimental Medicine. 177: 1215-1219. PMID 8459216 DOI: 10.1084/Jem.177.4.1215  0.538
1993 Kawakami K, Parker DC. Antigen and helper T lymphocytes activate B lymphocytes by distinct signaling pathways European Journal of Immunology. 23: 77-84. PMID 8419191  0.486
1993 Klaus SJ, Phillips NE, Parker DC. Effects of IL-4 and Fc gamma receptor II engagement on Egr-1 expression during stimulation of B lymphocytes by membrane immunoglobulin crosslinking. Molecular Immunology. 30: 1553-8. PMID 8232340 DOI: 10.1016/0161-5890(93)90463-L  0.386
1993 Parker DC. The functions of antigen recognition in T cell-dependent B cell activation Seminars in Immunology. 5: 413-420. PMID 8123796 DOI: 10.1006/Smim.1993.1047  0.619
1992 Eynon EE, Parker DC. Small B cells as antigen-presenting cells in the induction of tolerance to soluble protein antigens Journal of Experimental Medicine. 175: 131-138. PMID 1730913 DOI: 10.1084/Jem.175.1.131  0.527
1992 Kawakami K, Parker DC. Differences between T helper cell type I (Th1) and Th2 cell lines in signalling pathways for induction of contact-dependent T cell help European Journal of Immunology. 22: 85-93. PMID 1309700  0.488
1991 Parker DC, Eynon EE. Antigen presentation in acquired immunological tolerance Faseb Journal. 5: 2777-2784. PMID 1916102 DOI: 10.1096/Fasebj.5.13.1916102  0.478
1991 Takagi S, Daibata M, Last TJ, Humphreys RE, Parker DC, Sairenji T. Intracellular localization of tyrosine kinase substrates beneath crosslinked surface immunoglobulins in B cells Journal of Experimental Medicine. 174: 381-388. PMID 1713251 DOI: 10.1084/Jem.174.2.381  0.448
1990 Parker DC. How does the helper T cell activate the resting B cell when it recognizes antigen on the B-cell surface? Research in Immunology. 141: 405-407. PMID 2148422 DOI: 10.1016/0923-2494(90)90029-X  0.539
1990 Saga Y, Furukawa K, Rogers P, Tung JS, Parker D, Boyse EA. Further data on the selective expression of Ly-5 isoforms. Immunogenetics. 31: 296-306. PMID 2142476 DOI: 10.1007/Bf02115003  0.508
1985 Tony HP, Phillips NE, Parker DC. Role of membrane immunoglobulin (Ig) crosslinking in membrane Ig-mediated, major histocompatibility-restricted T cell-B cell cooperation. The Journal of Experimental Medicine. 162: 1695-708. PMID 3877141 DOI: 10.1084/Jem.162.5.1695  0.58
1985 Tony HP, Parker DC. Major hisocompatibility complex-restricted, polyclonal B cell responses resulting from helper T cell recognition of antimmunoglobulin presented by small B lymphocytes Journal of Experimental Medicine. 161: 223-241. PMID 3155791 DOI: 10.1084/Jem.161.1.223  0.563
1980 Parker DC. Induction and suppression of polyclonal antibody responses by anti-Ig reagents and antigen-nonspecific helper factors: a comparison of the effects of anti-Fab, anti-IgM, and anti IgD on murine B cells Immunological Reviews. 52: 115-139. PMID 7021394 DOI: 10.1111/J.1600-065X.1980.Tb00333.X  0.302
1980 Parker DC, Wadsworth DC, Schneider GB. Activation of murine B lymphocytes by anti-immunoglobulin is an inductive signal leading to immunoglobulin secretion Journal of Experimental Medicine. 152: 138-150. PMID 6967509 DOI: 10.1084/Jem.152.1.138  0.343
1975 Parker DC. Stimulation of mouse lymphocytes by insoluble anti-mouse immunoglobulin Nature. 258: 361-363. PMID 1081652 DOI: 10.1038/258361A0  0.395
1975 Gorczynski RM, Kilburn DG, Knight RA, Norbury C, Parker DC, Smith JB. Nonspecific and specific immuno-suppression in tumour-bearing mice by soluble immune complexes Nature. 254: 141-143. PMID 1078882 DOI: 10.1038/254141A0  0.446
1974 Feldmann M, Greaves MF, Parker DC, Rittenberg MB. Direct triggering of B lymphocytes by insolubilized antigen European Journal of Immunology. 4: 591-597. PMID 4609775 DOI: 10.1002/Eji.1830040903  0.473
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