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Thomas M. Connolly - Publications

Affiliations: 
1983 Vanderbilt University, Nashville, TN 
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23 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2013 Japp AG, Chelliah R, Tattersall L, Lang NN, Meng X, Weisel K, Katz A, Burt D, Fox KA, Feuerstein GZ, Connolly TM, Newby DE. Effect of PSI-697, a novel P-selectin inhibitor, on platelet-monocyte aggregate formation in humans. Journal of the American Heart Association. 2: e006007. PMID 23525448 DOI: 10.1161/JAHA.112.006007  0.44
2003 Selnick HG, Barrow JC, Nantermet PG, Connolly TM. Non-peptidic small-molecule antagonists of the human platelet thrombin receptor PAR-1 Current Medicinal Chemistry. Cardiovascular and Hematological Agents. 1: 47-59. PMID 15317290 DOI: 10.2174/1568016033356670  0.319
2002 Nantermet PG, Barrow JC, Lundell GF, Pellicore JM, Rittle KE, Young M, Freidinger RM, Connolly TM, Condra C, Karczewski J, Bednar RA, Gaul SL, Gould RJ, Prendergast K, Selnick HG. Discovery of a nonpeptidic small molecule antagonist of the human platelet thrombin receptor (PAR-1). Bioorganic & Medicinal Chemistry Letters. 12: 319-23. PMID 11814787 DOI: 10.1016/S0960-894X(01)00745-4  0.412
2001 Barrow JC, Nantermet PG, Selnick HG, Glass KL, Ngo PL, Young MB, Pellicore JM, Breslin MJ, Hutchinson JH, Freidinger RM, Condra C, Karczewski J, Bednar RA, Gaul SL, Stern A, ... ... Connolly TM, et al. Discovery and initial structure-activity relationships of trisubstituted ureas as thrombin receptor (PAR-1) antagonists. Bioorganic & Medicinal Chemistry Letters. 11: 2691-6. PMID 11591503 DOI: 10.1016/S0960-894X(01)00538-8  0.357
1995 Cook JJ, Sitko GR, Bednar B, Condra C, Mellott MJ, Feng DM, Nutt RF, Shafer JA, Gould RJ, Connolly TM. An antibody against the exosite of the cloned thrombin receptor inhibits experimental arterial thrombosis in the African green monkey. Circulation. 91: 2961-71. PMID 7796507 DOI: 10.1161/01.CIR.91.12.2961  0.329
1995 Bednar B, Condra C, Gould RJ, Connolly TM. Platelet aggregation monitored in a 96 well microplate reader is useful for evaluation of platelet agonists and antagonists. Thrombosis Research. 77: 453-63. PMID 7778060 DOI: 10.1016/0049-3848(95)93881-Y  0.417
1995 Lyle EM, Fujita T, Conner MW, Connolly TM, Vlasuk GP, Lynch JL. Effect of inhibitors of factor Xa or platelet adhesion, heparin, and aspirin on platelet deposition in an atherosclerotic rabbit model of angioplasty injury Journal of Pharmacological and Toxicological Methods. 33: 53-61. PMID 7727808 DOI: 10.1016/1056-8719(94)00057-B  0.34
1995 Karczewski J, Waxman L, Endris RG, Connolly TM. An inhibitor from the argasid tick Ornithodoros moubata of cell adhesion to collagen. Biochemical and Biophysical Research Communications. 208: 532-41. PMID 7695604 DOI: 10.1006/BBRC.1995.1371  0.458
1995 van Zanten GH, Connolly TM, Schiphorst ME, de Graaf S, Slootweg PJ, Sixma JJ. Recombinant leech antiplatelet protein specifically blocks platelet deposition on collagen surfaces under flow conditions. Arteriosclerosis, Thrombosis, and Vascular Biology. 15: 1424-31. PMID 7670958 DOI: 10.1161/01.ATV.15.9.1424  0.403
1994 van Zanten GH, de Graaf S, Slootweg PJ, Heijnen HF, Connolly TM, de Groot PG, Sixma JJ. Increased platelet deposition on atherosclerotic coronary arteries. The Journal of Clinical Investigation. 93: 615-32. PMID 8113399 DOI: 10.1172/JCI117014  0.305
1994 Connolly TM, Condra C, Feng D, Cook JJ, Stranieri MT, Reilly CF, Nutt RF, Gould RJ. Species Variability in Platelet and other Cellular Responsiveness to Thrombin Receptor-derived Peptides Thrombosis and Haemostasis. 72: 627-633. DOI: 10.1055/S-0038-1648926  0.362
1993 Schaffer LW, Davidson JT, Siegl PK, Gould RJ, Nutt RF, Brady SF, Connolly TM. Recombinant leech antiplatelet protein prevents collagen-mediated platelet aggregation but not collagen graft thrombosis in baboons. Arteriosclerosis and Thrombosis : a Journal of Vascular Biology / American Heart Association. 13: 1593-601. PMID 8218100 DOI: 10.1161/01.ATV.13.11.1593  0.443
1993 Keller P, Waxman L, Arnold B, Schultz L, Condra C, Connolly T. Cloning of the cDNA and expression of moubatin, an inhibitor of platelet aggregation. Journal of Biological Chemistry. 268: 5450-5456. DOI: 10.1016/s0021-9258(18)53342-1  0.42
1993 Waxman L, Connolly T. Isolation of an inhibitor selective for collagen-stimulated platelet aggregation from the soft tick Ornithodoros moubata. Journal of Biological Chemistry. 268: 5445-5449. DOI: 10.1016/s0021-9258(18)53341-x  0.419
1992 Keller P, Schultz L, Condra C, Karczewski J, Connolly T. An inhibitor of collagen-stimulated platelet activation from the salivary glands of the Haementeria officinalis leech. II. Cloning of the cDNA and expression. Journal of Biological Chemistry. 267: 6899-6904. DOI: 10.1016/s0021-9258(19)50513-0  0.337
1992 Connolly T, Jacobs J, Condra C. An inhibitor of collagen-stimulated platelet activation from the salivary glands of the Haementeria officinalis leech. I. Identification, isolation, and characterization. Journal of Biological Chemistry. 267: 6893-6898. DOI: 10.1016/s0021-9258(19)50512-9  0.389
1989 Mitchell CA, Connolly TM, Majerus PW. Identification and Isolation of a 75-kDa Inositol Polyphosphate-5-phosphatase from Human Platelets Journal of Biological Chemistry. 264: 8873-8877. DOI: 10.1016/S0021-9258(18)81874-9  0.381
1986 Connolly TM, Lawing WJ, Majerus PW. Protein kinase C phosphorylates human platelet inositol trisphosphate 5′-phosphomonoesterase, increasing the phosphatase activity Cell. 46: 951-958. PMID 3019558 DOI: 10.1016/0092-8674(86)90077-2  0.385
1986 Ishii H, Connolly TM, Bross TE, Majerus PW. Inositol cyclic trisphosphate [inositol 1,2-(cyclic)-4,5-trisphosphate] is formed upon thrombin stimulation of human platelets Proceedings of the National Academy of Sciences of the United States of America. 83: 6397-6401. PMID 3018731 DOI: 10.1073/Pnas.83.17.6397  0.494
1985 Connolly TM, Bross TE, Majerus PW. Isolation of a phosphomonoesterase from human platelets that specifically hydrolyzes the 5-phosphate of inositol 1,4,5-trisphosphate. Journal of Biological Chemistry. 260: 7868-7874. DOI: 10.1016/s0021-9258(17)39533-9  0.373
1985 Wilson DB, Connolly TM, Bross TE, Majerus PW, Sherman WR, Tyler AN, Rubin LJ, Brown JE. Isolation and characterization of the inositol cyclic phosphate products of polyphosphoinositide cleavage by phospholipase C. Physiological effects in permeabilized platelets and Limulus photoreceptor cells. Journal of Biological Chemistry. 260: 13496-13501. DOI: 10.1016/s0021-9258(17)38749-5  0.347
1983 Connolly TM, Limbird LE. Removal of extraplatelet Na+ eliminates indomethacin-sensitive secretion from human platelets stimulated by epinephrine, ADP, and thrombin. Proceedings of the National Academy of Sciences of the United States of America. 80: 5320-4. PMID 6577431 DOI: 10.1073/Pnas.80.17.5320  0.393
1983 Connolly TM, Limbird LE. The influence of Na+ on the alpha 2-adrenergic receptor system of human platelets. A method for removal of extraplatelet Na+. Effect of Na+ removal on aggregation, secretion, and cAMP accumulation. Journal of Biological Chemistry. 258: 3907-3912. DOI: 10.1016/s0021-9258(18)32753-4  0.391
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