Pierre Blier, MD, PhD - Publications

Affiliations: 
University of Ottawa, Ottawa, ON, Canada 

190 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Iro CM, Hamati R, El Mansari M, Blier P. Corrigendum to: Repeated but not Single Administration of Ketamine Prolongs Increases of the Firing Activity of Norepinephrine and Dopamine Neurons. The International Journal of Neuropsychopharmacology. PMID 34101803 DOI: 10.1093/ijnp/pyab029  0.8
2021 Iro CM, Hamati R, El Mansari M, Blier P. Repeated but not single administration of ketamine prolongs increases of the firing activity of norepinephrine and dopamine neurons. The International Journal of Neuropsychopharmacology. PMID 33674836 DOI: 10.1093/ijnp/pyab010  0.8
2020 El Mansari M, Ebrahimzadeh M, Hamati R, Iro CM, Farkas B, Kiss B, Adham N, Blier P. Long-term administration of cariprazine increases locus coeruleus noradrenergic neurons activity and serotonin receptor neurotransmission in the hippocampus. Journal of Psychopharmacology (Oxford, England). 269881120936891. PMID 32684081 DOI: 10.1177/0269881120936891  0.8
2020 Hamati R, El Mansari M, Blier P. Serotonin-2B receptor antagonism increases the activity of dopamine and glutamate neurons in the presence of selective serotonin reuptake inhibition. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 32473594 DOI: 10.1038/S41386-020-0723-Y  0.8
2018 Ebrahimzadeh M, El Mansari M, Blier P. Synergistic effect of aripiprazole and escitalopram in increasing serotonin but not norepinephrine neurotransmission in the rat hippocampus. Neuropharmacology. PMID 30414871 DOI: 10.1016/J.Neuropharm.2018.11.006  0.8
2018 Herman A, El Mansari M, Adham N, Kiss B, Farkas B, Blier P. Involvement of 5-HT and 5-HT Receptors but Not -Adrenoceptors in the Acute Electrophysiological Effects of Cariprazine in the Rat Brain In Vivo. Molecular Pharmacology. 94: 1363-1370. PMID 30322874 DOI: 10.1124/Mol.118.113290  0.8
2017 Ebrahimzadeh M, El Mansari M, Blier P. Partial inhibition of catecholamine activity and enhanced responsiveness to NMDA after sustained administration of vortioxetine. Neuropharmacology. PMID 29102760 DOI: 10.1016/J.Neuropharm.2017.10.036  0.8
2016 Kennedy SH, Lam RW, McIntyre RS, Tourjman SV, Bhat V, Blier P, Hasnain M, Jollant F, Levitt AJ, MacQueen GM, McInerney SJ, McIntosh D, Milev RV, Müller DJ, Parikh SV, et al. Canadian Network for Mood and Anxiety Treatments (CANMAT) 2016 Clinical Guidelines for the Management of Adults with Major Depressive Disorder: Section 3. Pharmacological Treatments. Canadian Journal of Psychiatry. Revue Canadienne De Psychiatrie. PMID 27486148 DOI: 10.1177/0706743716659417  0.76
2016 Nutt DJ, Blier P. Neuroscience-based Nomenclature (NbN) for Journal of Psychopharmacology. Journal of Psychopharmacology (Oxford, England). 30: 413-5. PMID 27098017 DOI: 10.1177/0269881116642903  0.76
2016 Oosterhof CA, El Mansari M, Merali Z, Blier P. Altered monoamine system activities after pRENATAL AND ADULT STRESs: A ROLE FOR STRESs RESILIENCE? Brain Research. PMID 27086968 DOI: 10.1016/J.Brainres.2016.04.032  0.76
2016 Lam RW, Milev R, Rotzinger S, Andreazza AC, Blier P, Brenner C, Daskalakis ZJ, Dharsee M, Downar J, Evans KR, Farzan F, Foster JA, Frey BN, Geraci J, Giacobbe P, et al. Discovering biomarkers for antidepressant response: protocol from the Canadian biomarker integration network in depression (CAN-BIND) and clinical characteristics of the first patient cohort. Bmc Psychiatry. 16: 105. PMID 27084692 DOI: 10.1186/S12888-016-0785-X  0.76
2016 Montoya A, Bruins R, Katzman MA, Blier P. The noradrenergic paradox: implications in the management of depression and anxiety. Neuropsychiatric Disease and Treatment. 12: 541-57. PMID 27042068 DOI: 10.2147/Ndt.S91311  0.76
2015 Zohar J, Stahl S, Moller HJ, Blier P, Kupfer D, Yamawaki S, Uchida H, Spedding M, Goodwin GM, Nutt D. A review of the current nomenclature for psychotropic agents and an introduction to the Neuroscience-based Nomenclature. European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology. PMID 26527055 DOI: 10.1016/J.Euroneuro.2015.08.019  0.76
2015 Oosterhof CA, El Mansari M, Bundgaard C, Blier P. Brexpiprazole alters monoaminergic systems following repeated administration: an in vivo electrophysiological study. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). PMID 26428352 DOI: 10.1093/Ijnp/Pyv111  0.8
2015 El Mansari M, Crnic A, Oosterhof C, Blier P. Long-term administration of the antidepressant vilazodone modulates rat brain monoaminergic systems. Neuropharmacology. 99: 696-704. PMID 26362359 DOI: 10.1016/J.Neuropharm.2015.09.007  0.76
2015 Phillips JL, Batten LA, Tremblay P, Aldosary F, Du L, Blier P. Impact of monoamine-related gene polymorphisms on hippocampal volume in treatment-resistant depression. Acta Neuropsychiatrica. 1-9. PMID 25990886 DOI: 10.1017/Neu.2015.25  0.76
2015 Frye MA, Blier P, Tye SJ. Concomitant benzodiazepine use attenuates ketamine response: implications for large scale study design and clinical development. Journal of Clinical Psychopharmacology. 35: 334-6. PMID 25928701 DOI: 10.1097/Jcp.0000000000000316  0.76
2015 Phillips JL, Batten LA, Tremblay P, Aldosary F, Blier P. A Prospective, Longitudinal Study of the Effect of Remission on Cortical Thickness and Hippocampal Volume in Patients with Treatment-Resistant Depression. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). 18. PMID 25829180 DOI: 10.1093/Ijnp/Pyv037  0.76
2015 El Iskandrani KS, Oosterhof CA, El Mansari M, Blier P. Impact of subanesthetic doses of ketamine on AMPA-mediated responses in rats: An in vivo electrophysiological study on monoaminergic and glutamatergic neurons. Journal of Psychopharmacology (Oxford, England). 29: 792-801. PMID 25759403 DOI: 10.1177/0269881115573809  0.76
2015 El Mansari M, Lecours M, Blier P. Effects of acute and sustained administration of vortioxetine on the serotonin system in the hippocampus: electrophysiological studies in the rat brain. Psychopharmacology. 232: 2343-52. PMID 25665528 DOI: 10.1007/S00213-015-3870-9  0.76
2015 Oosterhof CA, El Mansari M, Blier P. Asenapine alters the activity of monoaminergic systems following its subacute and long-term administration: an in vivo electrophysiological characterization. European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology. 25: 531-43. PMID 25656272 DOI: 10.1016/J.Euroneuro.2015.01.006  0.76
2015 Weissman MM, Wickramaratne P, Pilowsky DJ, Poh E, Batten LA, Hernandez M, Flament MF, Stewart JA, McGrath P, Blier P, Stewart JW. Treatment of maternal depression in a medication clinical trial and its effect on children. The American Journal of Psychiatry. 172: 450-9. PMID 25615566 DOI: 10.1176/Appi.Ajp.2014.13121679  0.76
2015 Fountoulakis KN, Gonda X, Baghai TC, Baldwin DS, Bauer M, Blier P, Gattaz W, Hasler G, Möller HJ, Tandon R, Vieta E, Kasper S. Report of the WPA section of pharmacopsychiatry on the relationship of antiepileptic drugs with suicidality in epilepsy. International Journal of Psychiatry in Clinical Practice. 1-10. PMID 25547437 DOI: 10.3109/13651501.2014.1000930  0.76
2015 El Mansari M, Manta S, Oosterhof C, El Iskandrani KS, Chenu F, Shim S, Blier P. Restoration of serotonin neuronal firing following long-term administration of bupropion but not paroxetine in olfactory bulbectomized rats. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). 18. PMID 25522394 DOI: 10.1093/Ijnp/Pyu050  0.76
2015 Smith DM, Fisher D, Blier P, Illivitsky V, Knott V. The separate and combined effects of monoamine oxidase inhibition and nicotine on P50 sensory gating. Psychopharmacology. 232: 1911-20. PMID 25466703 DOI: 10.1007/S00213-014-3823-8  0.76
2015 Smith DM, Fisher D, Blier P, Ilivitsky V, Knott V. The separate and combined effects of monoamine oxidase A inhibition and nicotine on the mismatch negativity event related potential Pharmacology Biochemistry and Behavior. 137: 44-52. DOI: 10.1016/j.pbb.2015.07.008  0.76
2014 Schatzberg AF, Blier P, Culpepper L, Jain R, Papakostas GI, Thase ME. An overview of vortioxetine. The Journal of Clinical Psychiatry. 75: 1411-8. PMID 25551236 DOI: 10.4088/Jcp.14027Ah1  0.76
2014 Gerra ML, Marchesi C, Amat JA, Blier P, Hellerstein DJ, Stewart JW. Does negative affectivity predict differential response to an SSRI versus a non-SSRI antidepressant? The Journal of Clinical Psychiatry. 75: e939-44. PMID 25295437 DOI: 10.4088/Jcp.14M09025  0.76
2014 Oosterhof CA, El Mansari M, Blier P. Acute effects of brexpiprazole on serotonin, dopamine, and norepinephrine systems: an in vivo electrophysiologic characterization. The Journal of Pharmacology and Experimental Therapeutics. 351: 585-95. PMID 25225185 DOI: 10.1124/Jpet.114.218578  0.76
2014 Katzman MA, Bleau P, Blier P, Chokka P, Kjernisted K, Van Ameringen M, Antony MM, Bouchard S, Brunet A, Flament M, Grigoriadis S, Mendlowitz S, O'Connor K, Rabheru K, et al. Canadian clinical practice guidelines for the management of anxiety, posttraumatic stress and obsessive-compulsive disorders. Bmc Psychiatry. 14: S1. PMID 25081580 DOI: 10.1186/1471-244X-14-S1-S1  0.76
2014 Weissman MM, Wickramaratne P, Pilowsky DJ, Poh E, Hernandez M, Batten LA, Flament MF, Stewart JW, Blier P. The effects on children of depressed mothers' remission and relapse over 9 months. Psychological Medicine. 44: 2811-24. PMID 25065614 DOI: 10.1017/S003329171400021X  0.76
2014 Pilowsky DJ, Wickramaratne P, Poh E, Hernandez M, Batten LA, Flament MF, Stewart JW, Blier P, Weissman MM. Psychopathology and functioning among children of treated depressed fathers and mothers. Journal of Affective Disorders. 164: 107-11. PMID 24856562 DOI: 10.1016/J.Jad.2014.04.012  0.76
2014 Jaworska N, Blondeau C, Tessier P, Norris S, Fusee W, Blier P, Knott V. Examining relations between alpha power as well as anterior cingulate cortex-localized theta activity and response to single or dual antidepressant pharmacotherapies. Journal of Psychopharmacology (Oxford, England). 28: 587-595. PMID 24557661 DOI: 10.1177/0269881114523862  0.76
2014 Stewart JW, McGrath PJ, Blondeau C, Deliyannides DA, Hellerstein D, Norris S, Amat J, Pilowsky DJ, Tessier P, Laberge L, O'Shea D, Chen Y, Withers A, Bergeron R, Blier P. Combination antidepressant therapy for major depressive disorder: speed and probability of remission. Journal of Psychiatric Research. 52: 7-14. PMID 24485847 DOI: 10.1016/J.Jpsychires.2013.12.001  0.76
2014 Chenu F, Shim S, El Mansari M, Blier P. Role of melatonin, serotonin 2B, and serotonin 2C receptors in modulating the firing activity of rat dopamine neurons. Journal of Psychopharmacology (Oxford, England). 28: 162-7. PMID 24189440 DOI: 10.1177/0269881113510071  0.76
2014 Blier P. Rational site-directed pharmacotherapy for major depressive disorder. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). 17: 997-1008. PMID 23745670 DOI: 10.1017/S1461145713000400  0.76
2013 Blier P. Neurotransmitter targeting in the treatment of depression. The Journal of Clinical Psychiatry. 74: 19-24. PMID 24191974 DOI: 10.4088/Jcp.12084Su1C.04  0.76
2013 Shim S, El Mansari M, Blier P. Modulation of the antidepressant-like effects of sustained administration of carisbamate and lamotrigine on monoaminergic systems: electrophysiological studies in the rat brain. The Journal of Pharmacology and Experimental Therapeutics. 347: 487-96. PMID 23986541 DOI: 10.1124/Jpet.113.203315  0.76
2013 Blier P. Exploiting N-methyl-d-aspartate channel blockade for a rapid antidepressant response in major depressive disorder. Biological Psychiatry. 74: 238-9. PMID 23885752 DOI: 10.1016/J.Biopsych.2013.05.029  0.76
2013 Phillips JL, Blier P. Ms Phillips and Dr Blier reply. The Journal of Clinical Psychiatry. 74: 631-2. PMID 23842018 DOI: 10.4088/Jcp.12Lr08004A  0.76
2013 Tsen P, El Mansari M, Blier P. Effects of repeated electroconvulsive shocks on catecholamine systems: electrophysiological studies in the rat brain. Synapse (New York, N.Y.). 67: 716-27. PMID 23740835 DOI: 10.1002/Syn.21685  0.76
2013 Jaworska N, De Somma E, Blondeau C, Tessier P, Norris S, Fusee W, Smith D, Blier P, Knott V. Auditory P3 in antidepressant pharmacotherapy treatment responders, non-responders and controls. European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology. 23: 1561-9. PMID 23664712 DOI: 10.1016/J.Euroneuro.2013.03.003  0.76
2013 Zajecka J, Kornstein SG, Blier P. Residual symptoms in major depressive disorder: prevalence, effects, and management. The Journal of Clinical Psychiatry. 74: 407-14. PMID 23656849 DOI: 10.4088/Jcp.12059Ah1  0.76
2013 Hamon M, Blier P. Monoamine neurocircuitry in depression and strategies for new treatments. Progress in Neuro-Psychopharmacology & Biological Psychiatry. 45: 54-63. PMID 23602950 DOI: 10.1016/J.Pnpbp.2013.04.009  0.76
2013 Blier P, El Mansari M. Serotonin and beyond: therapeutics for major depression. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 368: 20120536. PMID 23440470 DOI: 10.1098/rstb.2012.0536  0.76
2013 Zigman D, Blier P. Urgent ketamine infusion rapidly eliminated suicidal ideation for a patient with major depressive disorder: a case report. Journal of Clinical Psychopharmacology. 33: 270-2. PMID 23422387 DOI: 10.1097/Jcp.0B013E3182856865  0.76
2013 Jaworska N, Blondeau C, Tessier P, Norris S, Fusee W, Blier P, Knott V. Response prediction to antidepressants using scalp and source-localized loudness dependence of auditory evoked potential (LDAEP) slopes. Progress in Neuro-Psychopharmacology & Biological Psychiatry. 44: 100-7. PMID 23360662 DOI: 10.1016/J.Pnpbp.2013.01.012  0.76
2013 Chenu F, El Mansari M, Blier P. Electrophysiological effects of repeated administration of agomelatine on the dopamine, norepinephrine, and serotonin systems in the rat brain. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 38: 275-84. PMID 22871919 DOI: 10.1038/Npp.2012.140  0.76
2013 Manta S, El Mansari M, Debonnel G, Blier P. Electrophysiological and neurochemical effects of long-term vagus nerve stimulation on the rat monoaminergic systems. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). 16: 459-70. PMID 22717062 DOI: 10.1017/S1461145712000387  0.76
2012 Batten LA, Hernandez M, Pilowsky DJ, Stewart JW, Blier P, Flament MF, Poh E, Wickramaratne P, Weissman MM. Children of treatment-seeking depressed mothers: a comparison with the sequenced treatment alternatives to relieve depression (STAR*D) child study. Journal of the American Academy of Child and Adolescent Psychiatry. 51: 1185-96. PMID 23101744 DOI: 10.1016/J.Jaac.2012.08.020  0.76
2012 Jaworska N, Blier P, Fusee W, Knott V. α Power, α asymmetry and anterior cingulate cortex activity in depressed males and females. Journal of Psychiatric Research. 46: 1483-91. PMID 22939462 DOI: 10.1016/J.Jpsychires.2012.08.003  0.76
2012 Zigman D, Blier P. A framework to avoid irrational polypharmacy in psychiatry. Journal of Psychopharmacology (Oxford, England). 26: 1507-11. PMID 22767374 DOI: 10.1177/0269881112453211  0.76
2012 Fountoulakis KN, Kasper S, Andreassen O, Blier P, Okasha A, Severus E, Versiani M, Tandon R, Möller HJ, Vieta E. Efficacy of pharmacotherapy in bipolar disorder: a report by the WPA section on pharmacopsychiatry. European Archives of Psychiatry and Clinical Neuroscience. 262: 1-48. PMID 22622948 DOI: 10.1007/S00406-012-0323-X  0.76
2012 Koszycki D, Bisserbe JC, Blier P, Bradwejn J, Markowitz J. Interpersonal psychotherapy versus brief supportive therapy for depressed infertile women: first pilot randomized controlled trial. Archives of Women's Mental Health. 15: 193-201. PMID 22526405 DOI: 10.1007/S00737-012-0277-Z  0.76
2012 Blier P, Zigman D, Blier J. On the safety and benefits of repeated intravenous injections of ketamine for depression. Biological Psychiatry. 72: e11-2. PMID 22502989 DOI: 10.1016/J.Biopsych.2012.02.039  0.76
2012 Jaworska N, Blier P, Fusee W, Knott V. Scalp- and sLORETA-derived loudness dependence of auditory evoked potentials (LDAEPs) in unmedicated depressed males and females and healthy controls. Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology. 123: 1769-78. PMID 22425485 DOI: 10.1016/J.Clinph.2012.02.076  0.76
2012 Phillips JL, Batten LA, Aldosary F, Tremblay P, Blier P. Brain-volume increase with sustained remission in patients with treatment-resistant unipolar depression. The Journal of Clinical Psychiatry. 73: 625-31. PMID 22394416 DOI: 10.4088/Jcp.11M06865  0.76
2012 Chernoloz O, El Mansari M, Blier P. Effects of sustained administration of quetiapine alone and in combination with a serotonin reuptake inhibitor on norepinephrine and serotonin transmission. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 37: 1717-28. PMID 22373941 DOI: 10.1038/Npp.2012.18  0.76
2012 Blier P. Combined treatments for depression as for other medical disorders. The American Journal of Psychiatry. 169: 95; author reply 95-. PMID 22223012 DOI: 10.1176/Appi.Ajp.2011.11071055  0.76
2012 Ghanbari R, El Mansari M, Blier P. Electrophysiological impact of trazodone on the dopamine and norepinephrine systems in the rat brain. European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology. 22: 518-26. PMID 22154666 DOI: 10.1016/J.Euroneuro.2011.11.005  0.76
2012 Jaworska N, Blier P, Fusee W, Knott V. The temporal electrocortical profile of emotive facial processing in depressed males and females and healthy controls. Journal of Affective Disorders. 136: 1072-81. PMID 22127390 DOI: 10.1016/J.Jad.2011.10.047  0.76
2012 Baghai TC, Blier P, Baldwin DS, Bauer M, Goodwin GM, Fountoulakis KN, Kasper S, Leonard BE, Malt UF, Stein DJ, Versiani M, Möller HJ. Executive summary of the report by the WPA section on pharmacopsychiatry on general and comparative efficacy and effectiveness of antidepressants in the acute treatment of depressive disorders. European Archives of Psychiatry and Clinical Neuroscience. 262: 13-22. PMID 22083391 DOI: 10.1007/S00406-011-0274-7  0.76
2012 Manta S, El Mansari M, Blier P. Novel attempts to optimize vagus nerve stimulation parameters on serotonin neuronal firing activity in the rat brain. Brain Stimulation. 5: 422-9. PMID 22037140 DOI: 10.1016/J.Brs.2011.04.005  0.76
2012 Chernoloz O, El Mansari M, Blier P. Long-term administration of the dopamine D3/2 receptor agonist pramipexole increases dopamine and serotonin neurotransmission in the male rat forebrain. Journal of Psychiatry & Neuroscience : Jpn. 37: 113-21. PMID 22023785 DOI: 10.1503/Jpn.110038  0.76
2012 Chenu F, Ghanbari R, El Mansari M, Blier P. An enhancement of the firing activity of dopamine neurons as a common denominator of antidepressant treatments? The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). 15: 551-3; author reply . PMID 21906420 DOI: 10.1017/S1461145711001362  0.76
2012 Guiard BP, Mansari ME, Murphy DL, Blier P. Altered response to the selective serotonin reuptake inhibitor escitalopram in mice heterozygous for the serotonin transporter: an electrophysiological and neurochemical study. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). 15: 349-61. PMID 21439106 DOI: 10.1017/S1461145711000484  0.76
2011 Baghai TC, Blier P, Baldwin DS, Bauer M, Goodwin GM, Fountoulakis KN, Kasper S, Leonard BE, Malt UF, Stein D, Versiani M, Möller HJ. General and comparative efficacy and effectiveness of antidepressants in the acute treatment of depressive disorders: a report by the WPA section of pharmacopsychiatry. European Archives of Psychiatry and Clinical Neuroscience. 261: 207-45. PMID 22033583 DOI: 10.1007/S00406-011-0259-6  0.76
2011 Blier P, Briley M. The noradrenergic symptom cluster: clinical expression and neuropharmacology. Neuropsychiatric Disease and Treatment. 7: 15-20. PMID 21750624 DOI: 10.2147/Ndt.S19613  0.76
2011 Kennedy SH, Young AH, Blier P. Strategies to achieve clinical effectiveness: refining existing therapies and pursuing emerging targets. Journal of Affective Disorders. 132: S21-8. PMID 21571374 DOI: 10.1016/J.Jad.2011.03.048  0.76
2011 Ghanbari R, El Mansari M, Blier P. Enhancement of serotonergic and noradrenergic neurotransmission in the rat hippocampus by sustained administration of bupropion. Psychopharmacology. 217: 61-73. PMID 21445565 DOI: 10.1007/S00213-011-2260-1  0.76
2011 Berney A, Leyton M, Gravel P, Sibon I, Sookman D, Rosa Neto P, Diksic M, Nakai A, Pinard G, Todorov C, Okazawa H, Blier P, Nordahl TE, Benkelfat C. Brain regional α-[11C]methyl-L-tryptophan trapping in medication-free patients with obsessive-compulsive disorder. Archives of General Psychiatry. 68: 732-41. PMID 21383250 DOI: 10.1001/Archgenpsychiatry.2011.16  0.76
2011 Mnie-Filali O, Faure C, Lambás-Señas L, El Mansari M, Belblidia H, Gondard E, Etiévant A, Scarna H, Didier A, Berod A, Blier P, Haddjeri N. Pharmacological blockade of 5-HT7 receptors as a putative fast acting antidepressant strategy. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 36: 1275-88. PMID 21326194 DOI: 10.1038/Npp.2011.13  0.76
2011 Blier P, Blondeau C. Neurobiological bases and clinical aspects of the use of aripiprazole in treatment-resistant major depressive disorder. Journal of Affective Disorders. 128: S3-10. PMID 21220079 DOI: 10.1016/S0165-0327(11)70003-9  0.76
2011 Guiard BP, Chenu F, El Mansari M, Blier P. Characterization of the electrophysiological properties of triple reuptake inhibitors on monoaminergic neurons. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). 14: 211-23. PMID 20149268 DOI: 10.1017/S1461145710000076  0.76
2010 El-Mallakh RS, Kaur G, Lippman S. Placebo group needed for interpretation of combination trial. The American Journal of Psychiatry. 167: 996; author reply 99. PMID 20693473 DOI: 10.1176/Appi.Ajp.2010.10030453R  0.76
2010 Ghanbari R, El Mansari M, Blier P. Sustained administration of trazodone enhances serotonergic neurotransmission: in vivo electrophysiological study in the rat brain. The Journal of Pharmacology and Experimental Therapeutics. 335: 197-206. PMID 20647493 DOI: 10.1124/Jpet.110.169417  0.76
2010 Blier P. The well of novel antidepressants: running dry. Journal of Psychiatry & Neuroscience : Jpn. 35: 219-20. PMID 20569647 DOI: 10.1503/Jpn.100098  0.76
2010 El Mansari M, Guiard BP, Chernoloz O, Ghanbari R, Katz N, Blier P. Relevance of norepinephrine-dopamine interactions in the treatment of major depressive disorder. Cns Neuroscience & Therapeutics. 16: e1-17. PMID 20406250 DOI: 10.1111/J.1755-5949.2010.00146.X  0.76
2010 Blier P. Altered function of the serotonin 1A autoreceptor and the antidepressant response. Neuron. 65: 1-2. PMID 20152106 DOI: 10.1016/J.Neuron.2009.12.028  0.76
2010 Blier P, Ward HE, Tremblay P, Laberge L, Hébert C, Bergeron R. Combination of antidepressant medications from treatment initiation for major depressive disorder: a double-blind randomized study. The American Journal of Psychiatry. 167: 281-8. PMID 20008946 DOI: 10.1176/Appi.Ajp.2009.09020186  0.76
2010 Katz NS, Guiard BP, El Mansari M, Blier P. Effects of acute and sustained administration of the catecholamine reuptake inhibitor nomifensine on the firing activity of monoaminergic neurons. Journal of Psychopharmacology (Oxford, England). 24: 1223-35. PMID 19939862 DOI: 10.1177/0269881109348178  0.76
2010 Ghanbari R, El Mansari M, Blier P. Electrophysiological effects of the co-administration of escitalopram and bupropion on rat serotonin and norepinephrine neurons Journal of Psychopharmacology. 24: 39-50. PMID 18719044 DOI: 10.1177/0269881108095714  0.76
2010 Blier P. Reply to Smith letter American Journal of Psychiatry. 167: 995-996. DOI: 10.1176/Appi.Ajp.2010.10040468R  0.76
2010 Blier P. Compared with fl uoxetine monotherapy, mirtazapine plus venlafaxine or fl uoxetine increase remission but not response in patients with major depressive disorder Evidence-Based Mental Health. 13: 83. DOI: 10.1136/ebmh.13.3.83  0.76
2009 Blier P. Clarification regarding generic substitution for psychotropic drugs. Cns Spectrums. 14: 709-10. PMID 20394178 DOI: 10.1017/S1092852900023968  0.76
2009 Blier P. Generic substitution for psychotropic drugs. Cns Spectrums. 14: 1-7. PMID 20085109 DOI: 10.1017/S1092852900024706  0.76
2009 Dremencov E, el Mansari M, Blier P. Brain norepinephrine system as a target for antidepressant and mood stabilizing medications. Current Drug Targets. 10: 1061-8. PMID 19702556 DOI: 10.2174/138945009789735165  0.76
2009 Guiard BP, El Mansari M, Blier P. Prospect of a dopamine contribution in the next generation of antidepressant drugs: the triple reuptake inhibitors. Current Drug Targets. 10: 1069-84. PMID 19702555 DOI: 10.2174/138945009789735156  0.76
2009 Chenu F, Batten LA, Zernig G, Ladstaetter E, Hébert C, Blier P. Comparison of pharmacokinetic profiles of brand-name and generic formulations of citalopram and venlafaxine: a crossover study. The Journal of Clinical Psychiatry. 70: 958-66. PMID 19653973 DOI: 10.4088/Jcp.09M05315  0.76
2009 Chernoloz O, El Mansari M, Blier P. Electrophysiological studies in the rat brain on the basis for aripiprazole augmentation of antidepressants in major depressive disorder. Psychopharmacology. 206: 335-44. PMID 19641901 DOI: 10.1007/S00213-009-1611-7  0.76
2009 Manta S, Dong J, Debonnel G, Blier P. Enhancement of the function of rat serotonin and norepinephrine neurons by sustained vagus nerve stimulation. Journal of Psychiatry & Neuroscience : Jpn. 34: 272-80. PMID 19568478  0.76
2009 Dremencov E, El Mansari M, Blier P. Effects of sustained serotonin reuptake inhibition on the firing of dopamine neurons in the rat ventral tegmental area. Journal of Psychiatry & Neuroscience : Jpn. 34: 223-9. PMID 19448853  0.76
2009 Blier P, Gobbi G, Turcotte JE, de Montigny C, Boucher N, Hébert C, Debonnel G. Mirtazapine and paroxetine in major depression: a comparison of monotherapy versus their combination from treatment initiation. European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology. 19: 457-65. PMID 19345072 DOI: 10.1016/J.Euroneuro.2009.01.015  0.76
2009 Manta S, Dong J, Debonnel G, Blier P. Optimization of vagus nerve stimulation parameters using the firing activity of serotonin neurons in the rat dorsal raphe. European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology. 19: 250-5. PMID 19150228 DOI: 10.1016/J.Euroneuro.2008.12.001  0.76
2009 Blier P. Optimal use of antidepressants: when to act? Journal of Psychiatry & Neuroscience : Jpn. 34: 80. PMID 19125216  0.76
2009 Ghanbari R, El Mansari M, Shahid M, Blier P. Electrophysiological characterization of the effects of asenapine at 5-HT1A, 5-HT2A, α2-adrenergic and D2 receptors in the rat brain European Neuropsychopharmacology. 19: 177-187. PMID 19116183 DOI: 10.1016/J.Euroneuro.2008.11.001  0.76
2009 Chenu F, Mansari ME, Blier P. Long-term administration of monoamine oxidase inhibitors alters the firing rate and pattern of dopamine neurons in the ventral tegmental area International Journal of Neuropsychopharmacology. 12: 475-485. PMID 18700056 DOI: 10.1017/S1461145708009218  0.76
2009 Chernoloz O, Mansari ME, Blier P. Sustained administration of pramipexole modifies the spontaneous firing of dopamine, norepinephrine, and serotonin neurons in the rat brain Neuropsychopharmacology. 34: 651-661. PMID 18688211 DOI: 10.1038/Npp.2008.114  0.76
2009 Blier P. Psychopharmacology for the clinician psychopharmacologie pratique Journal of Psychiatry and Neuroscience. 34: 80.  0.76
2008 Haddjeri N, Blier P. Neurokinin-1 receptor antagonists modulate brain noradrenaline and serotonin interactions European Journal of Pharmacology. 600: 64-70. PMID 18930727 DOI: 10.1016/j.ejphar.2008.10.001  0.76
2008 Blier P. Resiliency of monoaminergic systems: The 80% rule and its relevance to drug development Journal of Psychopharmacology. 22: 587-589. PMID 18753271 DOI: 10.1177/0269881108095680  0.76
2008 El Mansari M, Ghanbari R, Janssen S, Blier P. Sustained administration of bupropion alters the neuronal activity of serotonin, norepinephrine but not dopamine neurons in the rat brain Neuropharmacology. 55: 1191-1198. PMID 18708076 DOI: 10.1016/J.Neuropharm.2008.07.028  0.76
2008 Guiard BP, El Mansari M, Blier P. Cross-talk between dopaminergic and noradrenergic systems in the rat ventral tegmental area, locus ceruleus, and dorsal hippocampus. Molecular Pharmacology. 74: 1463-75. PMID 18703671 DOI: 10.1124/Mol.108.048033  0.76
2008 Möller HJ, Baldwin DS, Goodwin G, Kasper S, Okasha A, Stein DJ, Tandon R, Versiani M. Do SSRIs or antidepressants in general increase suicidality? WPA Section on Pharmacopsychiatry: consensus statement. European Archives of Psychiatry and Clinical Neuroscience. 258: 3-23. PMID 18668279 DOI: 10.1007/S00406-008-3002-1  0.76
2008 Trivedi MH, Hollander E, Nutt D, Blier P. Clinical evidence and potential neurobiological underpinnings of unresolved symptoms of depression Journal of Clinical Psychiatry. 69: 246-258. PMID 18363453 DOI: 10.4088/Jcp.V69N0211  0.76
2008 Blier P. Do antidepressants really work? Journal of Psychiatry and Neuroscience. 33: 89-90. PMID 18330454  0.76
2008 Guiard BP, El Mansari M, Merali Z, Blier P. Functional interactions between dopamine, serotonin and norepinephrine neurons: an in-vivo electrophysiological study in rats with monoaminergic lesions. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). 11: 625-39. PMID 18205979 DOI: 10.1017/S1461145707008383  0.76
2008 El Mansari M, Blier P. In vivo electrophysiological assessment of the putative antidepressant Wf-516 in the rat raphe dorsalis, locus coeruleus and hippocampus Naunyn-Schmiedeberg's Archives of Pharmacology. 376: 351-361. PMID 18060386 DOI: 10.1007/S00210-007-0210-6  0.76
2008 Montgomery SA, Baldwin DS, Blier P, Fineberg NA, Kasper S, Lader M. Which antidepressants have demonstrated superior efficacy? A review of the evidence (International Clinical Psychopharmacology (2007) 22, 6, (323-329)) International Clinical Psychopharmacology. 23: 61.  0.76
2007 Montgomery SA, Baldwin DS, Blier P, Fineberg NA, Kasper S, Lader M, Lam RW, Lépine JP, Möller HJ, Nutt DJ, Rouillon F, Schatzberg AF, Thase ME. Which antidepressants have demonstrated superior efficacy? A review of the evidence. International Clinical Psychopharmacology. 22: 323-9. PMID 17917550 DOI: 10.1097/Yic.0B013E3282Eff7E0  0.76
2007 Blier P. Generic medications: Another variable in the treatment of illnesses Journal of Psychopharmacology. 21: 459-460. PMID 17664245 DOI: 10.1177/0269881107081126  0.76
2007 Blier P. The usefulness of large studies in psychopharmacology: Understanding their strong points and their drawbacks Journal of Psychiatry and Neuroscience. 32: 232-233. PMID 17653290  0.76
2007 Weiss M, Blier P, Montigny Cd. Effect of long-term administration of the antidepressant drug milnacipran on serotonergic and noradrenergic neurotransmission in the rat hippocampus Life Sciences. 81: 166-176. PMID 17568622 DOI: 10.1016/J.Lfs.2007.04.039  0.76
2007 Dremencov E, El Mansari M, Blier P. Distinct electrophysiological effects of paliperidone and risperidone on the firing activity of rat serotonin and norepinephrine neurons Psychopharmacology. 194: 63-72. PMID 17530476 DOI: 10.1007/S00213-007-0818-8  0.76
2007 Dremencov E, El Mansari M, Blier P. Noradrenergic Augmentation of Escitalopram Response by Risperidone: Electrophysiologic Studies in the Rat Brain Biological Psychiatry. 61: 671-678. PMID 16934772 DOI: 10.1016/J.Biopsych.2006.05.015  0.76
2007 Debonnel G, Saint-André E, Hébert C, De Montigny C, Lavoie N, Blier P. Differential physiological effects of a low dose and high doses of venlafaxine in major depression International Journal of Neuropsychopharmacology. 10: 51-61. PMID 16690006 DOI: 10.1017/S1461145705006413  0.76
2007 Blier P, Saint-André E, Hébert C, De Montigny C, Lavoie N, Debonnel G. Effects of different doses of venlafaxine on serotonin and norepinephrine reuptake in healthy volunteers International Journal of Neuropsychopharmacology. 10: 41-50. PMID 16690005 DOI: 10.1017/S1461145705006395  0.76
2007 Dunner DL, Blier P, Keller MB, Pollack MH, Thase ME, Zajecka JM. Preventing recurrent depression: Long-term treatment for major depressive disorder Primary Care Companion to the Journal of Clinical Psychiatry. 9: 214-223. DOI: 10.4088/Jcp.0307E06  0.76
2007 Blier P, Nutt D. Reply from the editors [2] Journal of Psychopharmacology. 21: 670. DOI: 10.1177/0269881107077607  0.76
2007 Blier P, Mansari ME. The importance of serotonin and noradrenaline in anxiety International Journal of Psychiatry in Clinical Practice. 11: 16-23. DOI: 10.1080/13651500701388310  0.76
2006 Blier P. Psychopharmacology for the clinician. Treating depression with selective norepinephrine reuptake inhibitors Journal of Psychiatry & Neuroscience : Jpn.. 31: 288. PMID 16862246  0.76
2006 Blier P. Pregnancy, depression, antidepressants and breast-feeding Journal of Psychiatry and Neuroscience. 31: 226-228. PMID 16862240  0.76
2006 Blier P, Habib R, Flament MF. Pharmacotherapies in the management of obsessive-compulsive disorder Canadian Journal of Psychiatry. 51: 417-430. PMID 16838823 DOI: 10.1177/070674370605100703  0.76
2006 Blier P. Media pressure and patient care Journal of Psychopharmacology. 20: 469-470. PMID 16760257 DOI: 10.1177/0269881106066432  0.76
2006 Schatzberg AF, Blier P, Delgado PL, Fava M, Haddad PM, Shelton RC. Antidepressant discontinuation syndrome: consensus panel recommendations for clinical management and additional research. The Journal of Clinical Psychiatry. 67: 27-30. PMID 16683860  0.76
2006 Blier P, Tremblay P. Physiologic mechanisms underlying the antidepressant discontinuation syndrome. The Journal of Clinical Psychiatry. 67: 8-13. PMID 16683857  0.76
2006 Tremblay P, Blier P. Catecholaminergic strategies for the treatment of major depression. Current Drug Targets. 7: 149-58. PMID 16475956 DOI: 10.2174/138945006775515464  0.76
2006 El Mansari M, Blier P. Mechanisms of action of current and potential pharmacotherapies of obsessive-compulsive disorder Progress in Neuro-Psychopharmacology and Biological Psychiatry. 30: 362-373. PMID 16427729 DOI: 10.1016/J.Pnpbp.2005.11.005  0.76
2006 Blier P. Dual serotonin and noradrenaline reuptake inhibitors: Focus on their differences International Journal of Psychiatry in Clinical Practice. 10: 22-32. DOI: 10.1080/13651500600645612  0.76
2006 Blier P. Reply: Practicing medicine on the basis of the unconfirmed and omitting the established facts [2] Journal of Psychiatry and Neuroscience. 31: 411-412.  0.76
2006 Blier P. The sequenced treatment alternatives to relieve depression (STAR*D): A first look at the initial pharmacotherapy results Clinical Neuropsychiatry. 3: 265-267.  0.76
2006 Blier P. Treating depression with selective norepinephrine reuptake inhibitors Journal of Psychiatry and Neuroscience. 31: 288.  0.76
2005 Blier P, Szabo ST. Potential mechanisms of action of atypical antipsychotic medications in treatment-resistant depression and anxiety. The Journal of Clinical Psychiatry. 66: 30-40. PMID 16336034  0.8
2005 Gobbi G, Blier P. Effect of neurokinin-1 receptor antagonists on serotoninergic, noradrenergic and hippocampal neurons: comparison with antidepressant drugs. Peptides. 26: 1383-93. PMID 16042978 DOI: 10.1016/J.Peptides.2005.03.032  0.76
2004 Rosa-Neto P, Diksic M, Okazawa H, Leyton M, Ghadirian N, Mzengeza S, Nakai A, Debonnel G, Blier P, Benkelfat C. Measurement of brain regional alpha-[11C]methyl-L-tryptophan trapping as a measure of serotonin synthesis in medication-free patients with major depression. Archives of General Psychiatry. 61: 556-63. PMID 15184235 DOI: 10.1001/Archpsyc.61.6.556  0.76
2004 Haddjeri N, Faure C, Lucas G, Mnie-Filali O, Chouvet G, Astier B, Renaud B, Blier P, Debonnel G. In-vivo modulation of central 5-hydroxytryptamine (5-HT1A) receptor-mediated responses by the cholinergic system. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). 7: 391-9. PMID 15140278 DOI: 10.1017/S1461145704004377  0.76
2004 Haddjeri N, Lavoie N, Blier P. Electrophysiological evidence for the tonic activation of 5-HT1A autoreceptors in the rat dorsal raphe nucleus Neuropsychopharmacology. 29: 1800-1806. PMID 15127086 DOI: 10.1038/Sj.Npp.1300489  0.76
2004 Szabo ST, Gold MS, Goldberger BA, Blier P. Effects of sustained gamma-hydroxybutyrate treatments on spontaneous and evoked firing activity of locus coeruleus norepinephrine neurons. Biological Psychiatry. 55: 934-9. PMID 15110737 DOI: 10.1016/J.Biopsych.2003.12.013  0.8
2003 Gobbi G, Slater S, Boucher N, Debonnel G, Blier P. Neurochemical and psychotropic effects of bupropion in healthy male subjects. Journal of Clinical Psychopharmacology. 23: 233-9. PMID 12826985 DOI: 10.1097/01.Jcp.0000084023.22282.03  0.76
2002 Szabo ST, Blier P. Effects of serotonin (5-hydroxytryptamine, 5-HT) reuptake inhibition plus 5-HT(2A) receptor antagonism on the firing activity of norepinephrine neurons. The Journal of Pharmacology and Experimental Therapeutics. 302: 983-91. PMID 12183655 DOI: 10.1124/Jpet.102.033282  0.8
2002 Stockmeier CA, Shi X, Konick L, Overholser JC, Jurjus G, Meltzer HY, Friedman L, Blier P, Rajkowska G. Neurokinin-1 receptors are decreased in major depressive disorder. Neuroreport. 13: 1223-7. PMID 12151774 DOI: 10.1097/00001756-200207020-00031  0.76
2002 Blier P, Seletti B, Gilbert F, Young SN, Benkelfat C. Serotonin 1A receptor activation and hypothermia in humans: lack of evidence for a presynaptic mediation. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 27: 301-8. PMID 12093604 DOI: 10.1016/S0893-133X(02)00318-4  0.76
2001 Szabo ST, Blier P. Response of the norepinephrine system to antidepressant drugs. Cns Spectrums. 6: 679-84. PMID 15520619 DOI: 10.1017/S1092852900001371  0.8
2001 Blier P, Haddjeri N, Szabo ST, Dong J. Enhancement of serotoninergic function - a sometimes insufficient cause of antidepressant action. Human Psychopharmacology. 16: 23-27. PMID 12404594 DOI: 10.1002/Hup.179  0.8
2001 Szabo ST, Blier P. Effects of the selective norepinephrine reuptake inhibitor reboxetine on norepinephrine and serotonin transmission in the rat hippocampus. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 25: 845-57. PMID 11750178 DOI: 10.1016/S0893-133X(01)00284-6  0.8
2001 Szabo ST, Blier P. Serotonin (1A) receptor ligands act on norepinephrine neuron firing through excitatory amino acid and GABA(A) receptors: a microiontophoretic study in the rat locus coeruleus. Synapse (New York, N.Y.). 42: 203-12. PMID 11746719 DOI: 10.1002/Syn.10009  0.8
2001 Szabo ST, Blier P. Functional and pharmacological characterization of the modulatory role of serotonin on the firing activity of locus coeruleus norepinephrine neurons. Brain Research. 922: 9-20. PMID 11730697 DOI: 10.1016/S0006-8993(01)03121-3  0.8
2001 Szabo ST, Blier P. Effects of chronic antidepressant drug administration and electroconvulsive shock on locus coeruleus electrophysiologic activity. Biological Psychiatry. 50: 644-6. PMID 11690604 DOI: 10.1016/S0006-3223(01)01260-4  0.8
2001 Szabo ST, Blier P. Effect of the selective noradrenergic reuptake inhibitor reboxetine on the firing activity of noradrenaline and serotonin neurons. The European Journal of Neuroscience. 13: 2077-87. PMID 11422448 DOI: 10.1046/J.0953-816X.2001.01583.X  0.8
2001 Leyton M, Okazawa H, Diksic M, Paris J, Rosa P, Mzengeza S, Young SN, Blier P, Benkelfat C. Brain Regional alpha-[11C]methyl-L-tryptophan trapping in impulsive subjects with borderline personality disorder. The American Journal of Psychiatry. 158: 775-82. PMID 11329401 DOI: 10.1176/Appi.Ajp.158.5.775  0.76
2001 Turcotte JE, Debonnel G, de Montigny C, Hébert C, Blier P. Assessment of the serotonin and norepinephrine reuptake blocking properties of duloxetine in healthy subjects. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 24: 511-21. PMID 11282251 DOI: 10.1016/S0893-133X(00)00220-7  0.76
2001 Santarelli L, Gobbi G, Debs PC, Sibille ET, Blier P, Hen R, Heath MJ. Genetic and pharmacological disruption of neurokinin 1 receptor function decreases anxiety-related behaviors and increases serotonergic function. Proceedings of the National Academy of Sciences of the United States of America. 98: 1912-7. PMID 11172050 DOI: 10.1073/Pnas.98.4.1912  0.76
2000 Szabo ST, de Montigny C, Blier P. Progressive attenuation of the firing activity of locus coeruleus noradrenergic neurons by sustained administration of selective serotonin reuptake inhibitors. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). 3: 1-11. PMID 11343573 DOI: 10.1017/S1461145700001772  0.8
2000 Leyton M, Ghadirian AM, Young SN, Palmour RM, Blier P, Helmers KF, Benkelfat C. Depressive relapse following acute tryptophan depletion in patients with major depressive disorder. Journal of Psychopharmacology (Oxford, England). 14: 284-7. PMID 11106310 DOI: 10.1177/026988110001400317  0.76
2000 Béïque JC, Blier P, de Montigny C, Debonnel G. Potentiation by (-)Pindolol of the activation of postsynaptic 5-HT(1A) receptors induced by venlafaxine. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 23: 294-306. PMID 10942853 DOI: 10.1016/S0893-133X(00)00112-3  0.76
2000 Béïque JC, Montigny CD, Blier P, Debonnel G. Effects of sustained administration of the serotonin and norepinephrine reuptake inhibitor venlafaxine: II. In vitro studies in the rat Neuropharmacology. 39: 1813-1822. PMID 10884562 DOI: 10.1016/S0028-3908(00)00018-6  0.76
2000 Béïque JC, De Montigny C, Blier P, Debonnel G. Effects of sustained administration of the serotonin and norepinephrine reuptake inhibitor venlafaxine: I. In vivo electrophysiological studies in the rat Neuropharmacology. 39: 1800-1812. PMID 10884561 DOI: 10.1016/S0028-3908(00)00017-4  0.76
2000 Rueter LE, Tecott LH, Blier P. In vivo electrophysiological examination of 5-HT2 responses in 5-HT2C receptor mutant mice. Naunyn-Schmiedeberg's Archives of Pharmacology. 361: 484-91. PMID 10832601 DOI: 10.1007/S002109900181  0.76
2000 Besson A, Haddjeri N, Blier P, de Montigny C. Effects of the co-administration of mirtazapine and paroxetine on serotonergic neurotransmission in the rat brain. European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology. 10: 177-88. PMID 10793320 DOI: 10.1016/S0924-977X(00)00069-9  0.44
2000 Haddjeri N, Szabo ST, de Montigny C, Blier P. Increased tonic activation of rat forebrain 5-HT(1A) receptors by lithium addition to antidepressant treatments. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 22: 346-56. PMID 10700654 DOI: 10.1016/S0893-133X(99)00138-4  0.8
2000 Leyton M, Young SN, Pihl RO, Etezadi S, Lauze C, Blier P, Baker GB, Benkelfat C. Effects on mood of acute phenylalanine/tyrosine depletion in healthy women. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 22: 52-63. PMID 10633491 DOI: 10.1016/S0893-133X(99)00086-X  0.76
1999 Leyton M, Young SN, Pihl RO, Etezadi S, Lauze C, Blier P, Baker GB, Benkelfat C. A comparison of the effects of acute tryptophan depletion and acute phenylalanine/tyrosine depletion in healthy women. Advances in Experimental Medicine and Biology. 467: 67-71. PMID 10721039 DOI: 10.1007/978-1-4615-4709-9_8  0.76
1999 De Montigny C, Silverstone PH, Debonnel G, Blier P, Bakish D. Venlafaxine in treatment-resistant major depression: A Canadian multicenter, open-label trial Journal of Clinical Psychopharmacology. 19: 401-406. PMID 10505581 DOI: 10.1097/00004714-199910000-00003  0.76
1999 Béïque JC, de Montigny C, Blier P, Debonnel G. Venlafaxine: discrepancy between in vivo 5-HT and NE reuptake blockade and affinity for reuptake sites. Synapse (New York, N.Y.). 32: 198-211. PMID 10340630 DOI: 10.1002/(Sici)1098-2396(19990601)32:3<198::Aid-Syn6>3.0.Co;2-2  0.76
1999 Rueter LE, Blier P. Electrophysiological examination of the effects of sustained flibanserin administration on serotonin receptors in rat brain. British Journal of Pharmacology. 126: 627-38. PMID 10188973 DOI: 10.1038/Sj.Bjp.0702344  0.76
1999 Szabo ST, de Montigny C, Blier P. Modulation of noradrenergic neuronal firing by selective serotonin reuptake blockers. British Journal of Pharmacology. 126: 568-71. PMID 10188964 DOI: 10.1038/Sj.Bjp.0702343  0.8
1998 Béïque JC, Debonnel G, de Montigny C, Blier P. Discrepancies between the in vitro and in vivo 5-HT and norepinephrine re-uptake blocking properties of venlafaxine. Annals of the New York Academy of Sciences. 861: 290-1. PMID 9928296 DOI: 10.1111/J.1749-6632.1998.Tb10230.X  0.76
1998 Ramboz S, Oosting R, Amara DA, Kung HF, Blier P, Mendelsohn M, Mann JJ, Brunner D, Hen R. Serotonin receptor 1A knockout: an animal model of anxiety-related disorder. Proceedings of the National Academy of Sciences of the United States of America. 95: 14476-81. PMID 9826725 DOI: 10.1073/Pnas.95.24.14476  0.76
1998 Béïque JC, de Montigny C, Blier P, Debonnel G. Blockade of 5-hydroxytryptamine and noradrenaline uptake by venlafaxine: a comparative study with paroxetine and desipramine. British Journal of Pharmacology. 125: 526-32. PMID 9806336 DOI: 10.1038/Sj.Bjp.0702074  0.76
1998 Rueter LE, Kasamo K, de Montigny C, Blier P. Effect of long-term administration of duloxetine on the function of serotonin and noradrenaline terminals in the rat brain. Naunyn-Schmiedeberg's Archives of Pharmacology. 357: 600-10. PMID 9686935 DOI: 10.1007/PL00005214  0.76
1998 Rueter LE, de Montigny C, Blier P. In vivo electrophysiological assessment of the agonistic properties of flibanserin at pre- and postsynaptic 5-HT1A receptors in the rat brain. Synapse (New York, N.Y.). 29: 392-405. PMID 9661257 DOI: 10.1002/(Sici)1098-2396(199808)29:4<392::Aid-Syn11>3.0.Co;2-T  0.76
1997 Nishizawa S, Benkelfat C, Young SN, Leyton M, Mzengeza S, de Montigny C, Blier P, Diksic M. Differences between males and females in rates of serotonin synthesis in human brain. Proceedings of the National Academy of Sciences of the United States of America. 94: 5308-13. PMID 9144233 DOI: 10.1073/Pnas.94.10.5308  0.76
1997 Leyton M, Young SN, Blier P, Ellenbogen MA, Palmour RM, Ghadirian AM, Benkelfat C. The effect of tryptophan depletion on mood in medication-free, former patients with major affective disorder. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 16: 294-7. PMID 9094147 DOI: 10.1016/S0893-133X(96)00262-X  0.76
1996 Romero L, Bel N, Artigas F, de Montigny C, Blier P. Effect of pindolol on the function of pre- and postsynaptic 5-HT1A receptors: in vivo microdialysis and electrophysiological studies in the rat brain. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 15: 349-60. PMID 8887989 DOI: 10.1016/0893-133X(95)00240-E  0.44
1996 Artigas F, Romero L, de Montigny C, Blier P. Acceleration of the effect of selected antidepressant drugs in major depression by 5-HT1A antagonists. Trends in Neurosciences. 19: 378-83. PMID 8873352 DOI: 10.1016/S0166-2236(96)10037-0  0.44
1995 Piñeyro G, Castanon N, Hen R, Blier P. Regulation of [3H]5-HT release in raphe, frontal cortex and hippocampus of 5-HT1B knock-out mice. Neuroreport. 7: 353-9. PMID 8742487 DOI: 10.1097/00001756-199512000-00084  0.76
1995 Hadrava V, Blier P, Dennis T, Ortemann C, de Montigny C. Characterization of 5-hydroxytryptamine1A properties of flesinoxan: in vivo electrophysiology and hypothermia study. Neuropharmacology. 34: 1311-26. PMID 8570029 DOI: 10.1016/0028-3908(95)00098-Q  0.44
1994 Blier P, Bouchard C. Modulation of 5-HT release in the guinea-pig brain following long-term adminstration of antidepressant drugs British Journal of Pharmacology. 113: 485-495. PMID 7834200 DOI: 10.1111/J.1476-5381.1994.Tb17015.X  0.76
1993 Blier P, Bouchard C. Functional characterization of a 5-HT3 receptor which modulates the release of 5-HT in the guinea-pig brain British Journal of Pharmacology. 108: 13-22. PMID 8428202 DOI: 10.1111/J.1476-5381.1993.Tb13433.X  0.76
1993 Blier P, Monroe PJ, Bouchard C, Smith DL, Smith DJ. 5-HT3 receptors which modulate [3H]5-HT release in the guinea pig hypothalamus are not autoreceptors Synapse. 15: 143-148. PMID 7505063 DOI: 10.1002/Syn.890150206  0.76
1992 Blier P, Bouchard C. Effect of repeated electroconvulsive shocks on serotonergic neurons European Journal of Pharmacology. 211: 365-373. PMID 1535597 DOI: 10.1016/0014-2999(92)90394-J  0.76
1992 Monnet FP, Blier P, Debonnel G, de Montigny C. Modulation by sigma ligands of N-methyl- D-aspartate-induced [3H]noradrenaline release in the rat hippocampus: G-protein dependency Naunyn-Schmiedeberg's Archives of Pharmacology. 346: 32-39. PMID 1407002 DOI: 10.1007/Bf00167567  0.76
1992 Galzin AM, Poirier MF, Lista A, Chodkiewicz JP, Blier P, Ramdine R, Loô H, Roux FX, Redondo A, Langer SZ. Characterization of the 5-hydroxytryptamine receptor modulating the release of 5-[3H]hydroxytryptamine in slices of the human neocortex. Journal of Neurochemistry. 59: 1293-301. PMID 1357094 DOI: 10.1111/J.1471-4159.1992.Tb08440.X  0.76
1991 Godbout R, Chaput Y, Blier P, de Montigny C. Tandospirone and its metabolite, 1-(2-pyrimidinyl)-piperazine--I. Effects of acute and long-term administration of tandospirone on serotonin neurotransmission. Neuropharmacology. 30: 679-90. PMID 1681446 DOI: 10.1016/0028-3908(91)90175-B  0.76
1989 Blier P, Galzin AM, Langer SZ. Diurnal variation in the function of serotonin terminals in the rat hypothalamus. Journal of Neurochemistry. 52: 453-9. PMID 2911025 DOI: 10.1111/J.1471-4159.1989.Tb09142.X  0.76
1989 Blier P, Ramdine R, Galzin AM, Langer SZ. Frequency-dependence of serotonin autoreceptor but not alpha 2-adrenoceptor inhibition of [3H]-serotonin release in rat hypothalamic slices. Naunyn-Schmiedeberg's Archives of Pharmacology. 339: 60-4. PMID 2566927 DOI: 10.1007/Bf00165127  0.76
1987 Blier P, de Montigny C, Tardif D. Short-term lithium treatment enhances responsiveness of postsynaptic 5-HT1A receptors without altering 5-HT autoreceptor sensitivity: an electrophysiological study in the rat brain. Synapse (New York, N.Y.). 1: 225-32. PMID 2850622 DOI: 10.1002/syn.890010302  0.44
1986 Blier P, de Montigny C, Azzaro AJ. Effect of repeated amiflamine administration on serotonergic and noradrenergic neurotransmission: electrophysiological studies in the rat CNS. Naunyn-Schmiedeberg's Archives of Pharmacology. 334: 253-60. PMID 3808082 DOI: 10.1007/BF00508779  0.76
1984 Blier P, de Montigny C, Tardif D. Effects of the two antidepressant drugs mianserin and indalpine on the serotonergic system: single-cell studies in the rat. Psychopharmacology. 84: 242-9. PMID 6438684 DOI: 10.1007/BF00427453  0.44
1981 de Montigny C, Blier P, Caillé G, Kouassi E. Pre- and postsynaptic effects of zimelidine and norzimelidine on the serotoninergic system: single cell studies in the rat. Acta Psychiatrica Scandinavica. Supplementum. 290: 79-90. PMID 6452807 DOI: 10.1111/J.1600-0447.1981.Tb00711.X  0.76
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