Xiaoxi Zhuang - Publications

Affiliations: 
University of Chicago, Chicago, IL 
Area:
Basal Ganglia, dopamine

58/100 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Cheung THC, Ding Y, Zhuang X, Kang UJ. Learning critically drives parkinsonian motor deficits through imbalanced striatal pathway recruitment. Proceedings of the National Academy of Sciences of the United States of America. 120: e2213093120. PMID 36920928 DOI: 10.1073/pnas.2213093120  0.395
2022 Chi W, Iyengar ASR, Albersen M, Bosma M, Verhoeven-Duif NM, Wu CF, Zhuang X. Correction to: Pyridox (am) ine 5'-phosphate oxidase deficiency induces seizures in Drosophila melanogaster. Human Molecular Genetics. PMID 35311996 DOI: 10.1093/hmg/ddac058  0.744
2022 Chi W, Iyengar ASR, Fu W, Liu W, Berg AE, Wu CF, Zhuang X. carrying epilepsy-associated variants in the vitamin B6 metabolism gene display allele- and diet-dependent phenotypes. Proceedings of the National Academy of Sciences of the United States of America. 119. PMID 35217610 DOI: 10.1073/pnas.2115524119  0.761
2021 Wildenberg G, Sorokina A, Koranda J, Monical A, Heer C, Sheffield M, Zhuang X, McGehee D, Kasthuri B. Partial connectomes of labeled dopaminergic circuits reveal non-synaptic communication and axonal remodeling after exposure to cocaine. Elife. 10. PMID 34965204 DOI: 10.7554/eLife.71981  0.768
2021 Chi W, Liu W, Fu W, Xia S, Heckscher ES, Zhuang X. RNA-binding protein syncrip regulates starvation-induced hyperactivity in adult Drosophila. Plos Genetics. 17: e1009396. PMID 33617535 DOI: 10.1371/journal.pgen.1009396  0.777
2019 Chi W, Iyengar ASR, Albersen M, Bosma M, Verhoeven-Duif NM, Wu CF, Zhuang X. Pyridox(am)ine 5'-phosphate oxidase deficiency induces seizures in Drosophila melanogaster. Human Molecular Genetics. PMID 31261385 DOI: 10.1093/Hmg/Ddz143  0.768
2018 Shi H, Zhang X, Weng YL, Lu Z, Liu Y, Lu Z, Li J, Hao P, Zhang Y, Zhang F, Wu Y, Delgado JY, Su Y, Patel MJ, Cao X, ... ... Zhuang X, et al. mA facilitates hippocampus-dependent learning and memory through YTHDF1. Nature. 563: 249-253. PMID 30401835 DOI: 10.1038/S41586-018-0666-1  0.79
2018 Koranda JL, Dore L, Shi H, Patel MJ, Vaasjo LO, Rao MN, Chen K, Lu Z, Yi Y, Chi W, He C, Zhuang X. Mettl14 Is Essential for Epitranscriptomic Regulation of Striatal Function and Learning. Neuron. 99: 283-292.e5. PMID 30056831 DOI: 10.1016/J.Neuron.2018.06.007  0.746
2017 Burbulla LF, Song P, Mazzulli JR, Zampese E, Wong YC, Jeon S, Santos DP, Blanz J, Obermaier CD, Strojny C, Savas JN, Kiskinis E, Zhuang X, Krüger R, Surmeier DJ, et al. Dopamine oxidation mediates mitochondrial and lysosomal dysfunction in Parkinson's disease. Science (New York, N.Y.). PMID 28882997 DOI: 10.1126/Science.Aam9080  0.383
2017 Chwen Y, Lee G, Yang Q, Chi W, Turkson SA, Du WA, Kemkemer C, Zeng ZB, Long M, Zhuang X. Genetic architecture of natural variation underlying adult foraging behavior that is essential for survival of Drosophila melanogaster. Genome Biology and Evolution. PMID 28472322 DOI: 10.1093/Gbe/Evx089  0.765
2016 Koranda JL, Krok AC, Xu J, Contractor A, McGehee DS, Beeler JA, Zhuang X. Chronic Nicotine Mitigates Aberrant Inhibitory Motor Learning Induced by Motor Experience under Dopamine Deficiency. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 36: 5228-40. PMID 27170121 DOI: 10.1523/Jneurosci.2754-15.2016  0.761
2015 Beeler JA, Faust RP, Turkson S, Ye H, Zhuang X. Low Dopamine D2 Receptor Increases Vulnerability to Obesity Via Reduced Physical Activity Not Increased Appetitive Motivation. Biological Psychiatry. PMID 26281715 DOI: 10.1016/J.Biopsych.2015.07.009  0.726
2015 Chen L, Xie Z, Turkson S, Zhuang X. A53T human α-synuclein overexpression in transgenic mice induces pervasive mitochondria macroautophagy defects preceding dopamine neuron degeneration. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 35: 890-905. PMID 25609609 DOI: 10.1523/JNEUROSCI.0089-14.2015  0.412
2014 Rappold PM, Cui M, Grima JC, Fan RZ, de Mesy-Bentley KL, Chen L, Zhuang X, Bowers WJ, Tieu K. Drp1 inhibition attenuates neurotoxicity and dopamine release deficits in vivo. Nature Communications. 5: 5244. PMID 25370169 DOI: 10.1038/Ncomms6244  0.322
2014 Augustin SM, Beeler JA, McGehee DS, Zhuang X. Cyclic AMP and afferent activity govern bidirectional synaptic plasticity in striatopallidal neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 6692-9. PMID 24806695 DOI: 10.1523/Jneurosci.3906-13.2014  0.795
2014 Chi W, Zhang L, Du W, Zhuang X. A nutritional conditional lethal mutant due to pyridoxine 5'-phosphate oxidase deficiency in Drosophila melanogaster. G3 (Bethesda, Md.). 4: 1147-54. PMID 24739647 DOI: 10.1534/G3.114.011130  0.756
2014 Cagniard B, Sotnikova TD, Gainetdinov RR, Zhuang X. The dopamine transporter expression level differentially affects responses to cocaine and amphetamine. Journal of Neurogenetics. 28: 112-21. PMID 24673634 DOI: 10.3109/01677063.2014.908191  0.414
2014 van Enkhuizen J, Geyer MA, Halberstadt AL, Zhuang X, Young JW. Dopamine depletion attenuates some behavioral abnormalities in a hyperdopaminergic mouse model of bipolar disorder. Journal of Affective Disorders. 155: 247-54. PMID 24287168 DOI: 10.1016/J.Jad.2013.08.041  0.411
2014 Koranda JL, Cone JJ, McGehee DS, Roitman MF, Beeler JA, Zhuang X. Nicotinic receptors regulate the dynamic range of dopamine release in vivo. Journal of Neurophysiology. 111: 103-11. PMID 24089398 DOI: 10.1152/Jn.00269.2013  0.789
2013 Zhuang X, Mazzoni P, Kang UJ. The role of neuroplasticity in dopaminergic therapy for Parkinson disease. Nature Reviews. Neurology. 9: 248-56. PMID 23588357 DOI: 10.1038/Nrneurol.2013.57  0.418
2012 Beeler JA, Frank MJ, McDaid J, Alexander E, Turkson S, Bernardez Sarria MS, Bernandez MS, McGehee DS, Zhuang X. A role for dopamine-mediated learning in the pathophysiology and treatment of Parkinson's disease. Cell Reports. 2: 1747-61. PMID 23246005 DOI: 10.1016/J.Celrep.2012.11.014  0.788
2012 Zhuang XX. Aberrant plasticity and "learned" motor inhibition in Parkinson's disease Sheng Li Xue Bao : [Acta Physiologica Sinica]. 64: 543-549. PMID 23090495  0.401
2012 Beeler JA, Frazier CR, Zhuang X. Putting desire on a budget: dopamine and energy expenditure, reconciling reward and resources. Frontiers in Integrative Neuroscience. 6: 49. PMID 22833718 DOI: 10.3389/Fnint.2012.00049  0.799
2012 Beeler JA, McCutcheon JE, Cao ZF, Murakami M, Alexander E, Roitman MF, Zhuang X. Taste uncoupled from nutrition fails to sustain the reinforcing properties of food. The European Journal of Neuroscience. 36: 2533-46. PMID 22712685 DOI: 10.1111/J.1460-9568.2012.08167.X  0.656
2012 Beeler JA, Frazier CR, Zhuang X. Dopaminergic enhancement of local food-seeking is under global homeostatic control. The European Journal of Neuroscience. 35: 146-59. PMID 22118191 DOI: 10.1111/J.1460-9568.2011.07916.X  0.802
2011 Shim JH, Yoon SH, Kim KH, Han JY, Ha JY, Hyun DH, Paek SH, Kang UJ, Zhuang X, Son JH. The antioxidant Trolox helps recovery from the familial Parkinson's disease-specific mitochondrial deficits caused by PINK1- and DJ-1-deficiency in dopaminergic neuronal cells. Mitochondrion. 11: 707-15. PMID 21664494 DOI: 10.1016/J.Mito.2011.05.013  0.329
2010 Beeler JA, Daw N, Frazier CR, Zhuang X. Tonic dopamine modulates exploitation of reward learning. Frontiers in Behavioral Neuroscience. 4: 170. PMID 21120145 DOI: 10.3389/Fnbeh.2010.00170  0.825
2010 Beeler JA, Cao ZF, Kheirbek MA, Ding Y, Koranda J, Murakami M, Kang UJ, Zhuang X. Dopamine-dependent motor learning: insight into levodopa's long-duration response. Annals of Neurology. 67: 639-47. PMID 20437561 DOI: 10.1002/Ana.21947  0.779
2010 Kheirbek MA, Beeler JA, Chi W, Ishikawa Y, Zhuang X. A molecular dissociation between cued and contextual appetitive learning. Learning & Memory (Cold Spring Harbor, N.Y.). 17: 148-54. PMID 20189959 DOI: 10.1101/Lm.1687310  0.773
2010 Balci F, Ludvig EA, Abner R, Zhuang X, Poon P, Brunner D. Motivational effects on interval timing in dopamine transporter (DAT) knockdown mice. Brain Research. 1325: 89-99. PMID 20167208 DOI: 10.1016/J.Brainres.2010.02.034  0.427
2009 Perry W, Minassian A, Paulus MP, Young JW, Kincaid MJ, Ferguson EJ, Henry BL, Zhuang X, Masten VL, Sharp RF, Geyer MA. A reverse-translational study of dysfunctional exploration in psychiatric disorders: from mice to men. Archives of General Psychiatry. 66: 1072-80. PMID 19805697 DOI: 10.1001/Archgenpsychiatry.2009.58  0.328
2009 Kheirbek MA, Britt JP, Beeler JA, Ishikawa Y, McGehee DS, Zhuang X. Adenylyl cyclase type 5 contributes to corticostriatal plasticity and striatum-dependent learning. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 12115-24. PMID 19793969 DOI: 10.1523/Jneurosci.3343-09.2009  0.817
2009 Xie Z, Zhuang X, Chen L. DJ-1 mRNA anatomical localization and cell type identification in the mouse brain. Neuroscience Letters. 465: 214-9. PMID 19766170 DOI: 10.1016/j.neulet.2009.09.024  0.388
2009 Beeler JA, Cao ZF, Kheirbek MA, Zhuang X. Loss of cocaine locomotor response in Pitx3-deficient mice lacking a nigrostriatal pathway. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 34: 1149-61. PMID 18704092 DOI: 10.1038/Npp.2008.117  0.799
2008 Kheirbek MA, Beeler JA, Ishikawa Y, Zhuang X. A cAMP pathway underlying reward prediction in associative learning. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 11401-8. PMID 18971482 DOI: 10.1523/Jneurosci.4115-08.2008  0.809
2008 Frazier CR, Mason P, Zhuang X, Beeler JA. Sucrose exposure in early life alters adult motivation and weight gain. Plos One. 3: e3221. PMID 18797507 DOI: 10.1371/Journal.Pone.0003221  0.767
2008 Chen L, Ding Y, Cagniard B, Van Laar AD, Mortimer A, Chi W, Hastings TG, Kang UJ, Zhuang X. Unregulated cytosolic dopamine causes neurodegeneration associated with oxidative stress in mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 425-33. PMID 18184785 DOI: 10.1523/Jneurosci.3602-07.2008  0.815
2007 Yang W, Chen L, Ding Y, Zhuang X, Kang UJ. Paraquat induces dopaminergic dysfunction and proteasome impairment in DJ-1-deficient mice. Human Molecular Genetics. 16: 2900-10. PMID 17823202 DOI: 10.1093/Hmg/Ddm249  0.395
2007 Tilley MR, Cagniard B, Zhuang X, Han DD, Tiao N, Gu HH. Cocaine reward and locomotion stimulation in mice with reduced dopamine transporter expression. Bmc Neuroscience. 8: 42. PMID 17584943 DOI: 10.1186/1471-2202-8-42  0.388
2007 Wu N, Cepeda C, Zhuang X, Levine MS. Altered corticostriatal neurotransmission and modulation in dopamine transporter knock-down mice. Journal of Neurophysiology. 98: 423-32. PMID 17522168 DOI: 10.1152/jn.00971.2006  0.35
2007 Sanders AC, Hussain AJ, Hen R, Zhuang X. Chronic blockade or constitutive deletion of the serotonin transporter reduces operant responding for food reward. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 32: 2321-9. PMID 17356573 DOI: 10.1038/Sj.Npp.1301368  0.638
2007 Kramer ER, Aron L, Ramakers GM, Seitz S, Zhuang X, Beyer K, Smidt MP, Klein R. Absence of Ret signaling in mice causes progressive and late degeneration of the nigrostriatal system. Plos Biology. 5: e39. PMID 17298183 DOI: 10.1371/Journal.Pbio.0050039  0.303
2006 Cagniard B, Beeler JA, Britt JP, McGehee DS, Marinelli M, Zhuang X. Dopamine scales performance in the absence of new learning. Neuron. 51: 541-7. PMID 16950153 DOI: 10.1016/J.Neuron.2006.07.026  0.79
2006 Beeler JA, Prendergast B, Zhuang X. Low amplitude entrainment of mice and the impact of circadian phase on behavior tests. Physiology & Behavior. 87: 870-80. PMID 16600314 DOI: 10.1016/J.Physbeh.2006.01.037  0.627
2006 Yin HH, Zhuang X, Balleine BW. Instrumental learning in hyperdopaminergic mice. Neurobiology of Learning and Memory. 85: 283-8. PMID 16423542 DOI: 10.1016/J.Nlm.2005.12.001  0.324
2006 Cagniard B, Balsam PD, Brunner D, Zhuang X. Mice with chronically elevated dopamine exhibit enhanced motivation, but not learning, for a food reward. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 31: 1362-70. PMID 16319913 DOI: 10.1038/sj.npp.1300966  0.478
2005 Chen L, Cagniard B, Mathews T, Jones S, Koh HC, Ding Y, Carvey PM, Ling Z, Kang UJ, Zhuang X. Age-dependent motor deficits and dopaminergic dysfunction in DJ-1 null mice. The Journal of Biological Chemistry. 280: 21418-26. PMID 15799973 DOI: 10.1074/Jbc.M413955200  0.459
2005 Zhuang X, Masson J, Gingrich JA, Rayport S, Hen R. Targeted gene expression in dopamine and serotonin neurons of the mouse brain. Journal of Neuroscience Methods. 143: 27-32. PMID 15763133 DOI: 10.1016/j.jneumeth.2004.09.020  0.678
2005 Berridge KC, Aldridge JW, Houchard KR, Zhuang X. Sequential super-stereotypy of an instinctive fixed action pattern in hyper-dopaminergic mutant mice: a model of obsessive compulsive disorder and Tourette's. Bmc Biology. 3: 4. PMID 15710042 DOI: 10.1186/1741-7007-3-4  0.38
2004 Chuhma N, Zhang H, Masson J, Zhuang X, Sulzer D, Hen R, Rayport S. Dopamine neurons mediate a fast excitatory signal via their glutamatergic synapses. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 972-81. PMID 14749442 DOI: 10.1523/JNEUROSCI.4317-03.2004  0.746
2003 Peciña S, Cagniard B, Berridge KC, Aldridge JW, Zhuang X. Hyperdopaminergic mutant mice have higher "wanting" but not "liking" for sweet rewards. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 9395-402. PMID 14561867 DOI: 10.1523/Jneurosci.23-28-09395.2003  0.477
2003 Chen L, Zhuang X. Transgenic mouse models of dopamine deficiency. Annals of Neurology. 54: S91-102. PMID 12891659 DOI: 10.1002/ana.10655  0.372
2003 Ralph-Williams RJ, Paulus MP, Zhuang X, Hen R, Geyer MA. Valproate attenuates hyperactive and perseverative behaviors in mutant mice with a dysregulated dopamine system. Biological Psychiatry. 53: 352-9. PMID 12586455 DOI: 10.1016/S0006-3223(02)01489-0  0.687
2002 Gross C, Zhuang X, Stark K, Ramboz S, Oosting R, Kirby L, Santarelli L, Beck S, Hen R. Serotonin1A receptor acts during development to establish normal anxiety-like behaviour in the adult. Nature. 416: 396-400. PMID 11919622 DOI: 10.1038/416396A  0.778
2000 Gross C, Santarelli L, Brunner D, Zhuang X, Hen R. Altered fear circuits in 5-HT(1A) receptor KO mice. Biological Psychiatry. 48: 1157-63. PMID 11137057 DOI: 10.1016/S0006-3223(00)01041-6  0.59
2000 Zhuang X, Belluscio L, Hen R. GOLFα Mediates Dopamine D1 Receptor Signaling The Journal of Neuroscience. 20: RC91-RC91. DOI: 10.1523/JNEUROSCI.20-16-j0001.2000  0.639
1999 Zhuang X, Gross C, Santarelli L, Compan V, Trillat AC, Hen R. Altered emotional states in knockout mice lacking 5-HT1A or 5-HT1B receptors. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 21: 52S-60S. PMID 10432489 DOI: 10.1016/S0893-133X(99)00047-0  0.748
1999 Grailhe R, Waeber C, Dulawa SC, Hornung JP, Zhuang X, Brunner D, Geyer MA, Hen R. Increased exploratory activity and altered response to LSD in mice lacking the 5-HT(5A) receptor. Neuron. 22: 581-91. PMID 10197537 DOI: 10.1016/S0896-6273(00)80712-6  0.596
Low-probability matches (unlikely to be authored by this person)
2013 Choi I, Kim J, Jeong HK, Kim B, Jou I, Park SM, Chen L, Kang UJ, Zhuang X, Joe EH. PINK1 deficiency attenuates astrocyte proliferation through mitochondrial dysfunction, reduced AKT and increased p38 MAPK activation, and downregulation of EGFR. Glia. 61: 800-12. PMID 23440919 DOI: 10.1002/Glia.22475  0.294
2014 Lin W, Wadlington NL, Chen L, Zhuang X, Brorson JR, Kang UJ. Loss of PINK1 attenuates HIF-1α induction by preventing 4E-BP1-dependent switch in protein translation under hypoxia. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 3079-89. PMID 24553947 DOI: 10.1523/Jneurosci.2286-13.2014  0.293
2018 Weng YL, Wang X, An R, Cassin J, Vissers C, Liu Y, Liu Y, Xu T, Wang X, Wong SZH, Joseph J, Dore LC, Dong Q, Zheng W, Jin P, ... ... Zhuang X, et al. Epitranscriptomic m6A Regulation of Axon Regeneration in the Adult Mammalian Nervous System. Neuron. 97: 313-325.e6. PMID 29346752 DOI: 10.1016/J.Neuron.2017.12.036  0.281
2013 Song S, Jang S, Park J, Bang S, Choi S, Kwon KY, Zhuang X, Kim E, Chung J. Characterization of PINK1 (PTEN-induced putative kinase 1) mutations associated with Parkinson disease in mammalian cells and Drosophila. The Journal of Biological Chemistry. 288: 5660-72. PMID 23303188 DOI: 10.1074/Jbc.M112.430801  0.264
2009 Xiong H, Wang D, Chen L, Choo YS, Ma H, Tang C, Xia K, Jiang W, Ronai Z, Zhuang X, Zhang Z. Parkin, PINK1, and DJ-1 form a ubiquitin E3 ligase complex promoting unfolded protein degradation. The Journal of Clinical Investigation. 119: 650-60. PMID 19229105 DOI: 10.1172/Jci37617  0.264
2019 Xu H, Dzhashiashvili Y, Shah A, Kunjamma RB, Weng YL, Elbaz B, Fei Q, Jones JS, Li YI, Zhuang X, Ming GL, He C, Popko B. mA mRNA Methylation Is Essential for Oligodendrocyte Maturation and CNS Myelination. Neuron. PMID 31901304 DOI: 10.1016/J.Neuron.2019.12.013  0.25
2017 Yoon KJ, Ringeling FR, Vissers C, Jacob F, Pokrass M, Jimenez-Cyrus D, Su Y, Kim NS, Zhu Y, Zheng L, Kim S, Wang X, Doré LC, Jin P, Regot S, ... Zhuang X, et al. Temporal Control of Mammalian Cortical Neurogenesis by m(6)A Methylation. Cell. PMID 28965759 DOI: 10.1016/J.Cell.2017.09.003  0.248
2003 Peciña S, Cagniard B, Berridge KC, Aldridge JW, Zhuang X. Hyperdopaminergic Mutant Mice Have Higher “Wanting” But Not “Liking” for Sweet Rewards The Journal of Neuroscience. 23: 9395-9402. DOI: 10.1523/JNEUROSCI.23-28-09395.2003  0.247
2008 Malhotra D, Thimmulappa R, Navas-Acien A, Sandford A, Elliott M, Singh A, Chen L, Zhuang X, Hogg J, Pare P, Tuder RM, Biswal S. Expression of concern: Decline in NRF2-regulated antioxidants in chronic obstructive pulmonary disease lungs due to loss of its positive regulator, DJ-1. American Journal of Respiratory and Critical Care Medicine. 178: 592-604. PMID 18556627 DOI: 10.1164/Rccm.200803-380Oc  0.238
2008 Narboux-Nême N, Pavone LM, Avallone L, Zhuang X, Gaspar P. Serotonin transporter transgenic (SERTcre) mouse line reveals developmental targets of serotonin specific reuptake inhibitors (SSRIs). Neuropharmacology. 55: 994-1005. PMID 18789954 DOI: 10.1016/J.Neuropharm.2008.08.020  0.2
2023 Zou Z, Wei J, Chen Y, Kang Y, Shi H, Yang F, Shi Z, Chen S, Zhou Y, Sepich-Poore C, Zhuang X, Zhou X, Jiang H, Wen Z, Jin P, et al. FMRP phosphorylation modulates neuronal translation through YTHDF1. Molecular Cell. PMID 37949069 DOI: 10.1016/j.molcel.2023.10.028  0.197
2022 Sepich-Poore C, Zheng Z, Schmitt E, Wen K, Zhang ZS, Cui XL, Dai Q, Zhu AC, Zhang L, Sanchez Castillo A, Tan H, Peng J, Zhuang X, He C, Nachtergaele S. The METTL5-TRMT112 N-methyladenosine methyltransferase complex regulates mRNA translation via 18S rRNA methylation. The Journal of Biological Chemistry. 101590. PMID 35033535 DOI: 10.1016/j.jbc.2022.101590  0.166
2015 Xu S, Mao L, Ding P, Zhuang X, Zhou Y, Yu L, Liu Y, Nie T, Xu T, Xu Y, Liu J, Smaill J, Ren X, Wu D, Ding K. 1-Benzyl-4-phenyl-1H-1,2,3-triazoles improve the transcriptional functions of estrogen-related receptor γ and promote the browning of white adipose. Bioorganic & Medicinal Chemistry. 23: 3751-60. PMID 25910584 DOI: 10.1016/J.Bmc.2015.03.082  0.115
2012 Rappold P, Lim S, Cui M, Chen L, Bowers W, Zhuang X, Tieu K. 3.246 BLOCKING DRP-1 FUNCTION IS NEUROPROTECTIVE IN ANIMAL MODELS OF PARKINSON'S DISEASE Parkinsonism & Related Disorders. 18: S215. DOI: 10.1016/S1353-8020(11)70918-X  0.109
2021 Wu X, Shen H, Zhang Y, Wang C, Li Q, Zhang C, Zhuang X, Li C, Shi Y, Xing Y, Xiang Q, Xu J, Wu D, Liu J, Xu Y. Discovery and Characterization of Benzimidazole Derivative XY123 as a Potent, Selective, and Orally Available RORγ Inverse Agonist. Journal of Medicinal Chemistry. PMID 34121397 DOI: 10.1021/acs.jmedchem.1c00763  0.102
2022 Li Q, Yao B, Zhao S, Lu Z, Zhang Y, Xiang Q, Wu X, Yu H, Zhang C, Li J, Zhuang X, Wu D, Li Y, Xu Y. Discovery of a Highly Selective and H435R-Sensitive Thyroid Hormone Receptor β Agonist. Journal of Medicinal Chemistry. PMID 35507418 DOI: 10.1021/acs.jmedchem.2c00144  0.1
1996 Huang XZ, Wu JF, Cass D, Erle DJ, Corry D, Young SG, Farese RV, Sheppard D. Inactivation of the integrin beta 6 subunit gene reveals a role of epithelial integrins in regulating inflammation in the lung and skin. The Journal of Cell Biology. 133: 921-8. PMID 8666675 DOI: 10.1083/Jcb.133.4.921  0.09
2013 Ren X, Pan X, Zhang Z, Wang D, Lu X, Li Y, Wen D, Long H, Luo J, Feng Y, Zhuang X, Zhang F, Liu J, Leng F, Lang X, et al. Identification of GZD824 as an orally bioavailable inhibitor that targets phosphorylated and nonphosphorylated breakpoint cluster region-Abelson (Bcr-Abl) kinase and overcomes clinically acquired mutation-induced resistance against imatinib. Journal of Medicinal Chemistry. 56: 879-94. PMID 23301703 DOI: 10.1021/jm301581y  0.089
1993 Zhuang X, Silverman AJ, Silver R. Reproductive behavior, endocrine state, and the distribution of GnRH-like immunoreactive mast cells in dove brain. Hormones and Behavior. 27: 283-95. PMID 8225253 DOI: 10.1006/hbeh.1993.1021  0.087
2022 Zhang HJ, Zammit M, Kao CM, Govind AP, Mitchell S, Holderman N, Bhuiyan M, Freifelder R, Zhuang X, Mukherjee J, Chen CT, Green WN. Trapping of Nicotinic Acetylcholine Receptor Ligands Assayed by Cellular Studies and PET Imaging. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 36028313 DOI: 10.1523/JNEUROSCI.2484-21.2022  0.083
2017 Guo Y, Zhuang X, Huang Z, Zou J, Yang D, Hu X, Du Z, Wang L, Liao X. Klotho protects the heart from hyperglycemia-induced injury by inactivating ROS and NF-κB-mediated inflammation both in vitro and in vivo. Biochimica Et Biophysica Acta. PMID 28982613 DOI: 10.1016/j.bbadis.2017.09.029  0.082
2013 Xu S, Zhuang X, Pan X, Zhang Z, Duan L, Liu Y, Zhang L, Ren X, Ding K. 1-Phenyl-4-benzoyl-1H-1,2,3-triazoles as orally bioavailable transcriptional function suppressors of estrogen-related receptor α. Journal of Medicinal Chemistry. 56: 4631-40. PMID 23656512 DOI: 10.1021/jm4003928  0.078
1997 Zhuang X, Silverman AJ, Silver R. Mast cell number and maturation in the central nervous system: influence of tissue type, location and exposure to steroid hormones. Neuroscience. 80: 1237-45. PMID 9284073 DOI: 10.1016/S0306-4522(97)00052-3  0.078
2023 Xiang Q, Wu T, Zhang C, Wang C, Xu H, Hu Q, Hu J, Luo G, Zhuang X, Wu X, Zhang Y, Xu Y. Discovery of a potent and selective CBP bromodomain inhibitor (Y08262) for treating acute myeloid leukemia. Bioorganic Chemistry. 142: 106950. PMID 37924753 DOI: 10.1016/j.bioorg.2023.106950  0.073
2022 Kang UJ, Nakamura K, Zhuang X. Reader Response: Safety of AADC Gene Therapy for Moderately Advanced Parkinson Disease: Three-Year Outcomes From the PD-1101 Trial. Neurology. 99: 258-259. PMID 35940895 DOI: 10.1212/WNL.0000000000201002  0.071
2015 Lu X, Zhang Z, Ren X, Pan X, Wang D, Zhuang X, Luo J, Yu R, Ding K. Hybrid pyrimidine alkynyls inhibit the clinically resistance related Bcr-Abl(T315I) mutant. Bioorganic & Medicinal Chemistry Letters. PMID 26195136 DOI: 10.1016/j.bmcl.2015.07.006  0.07
2015 Li Y, Cheng H, Zhang Z, Zhuang X, Luo J, Long H, Zhou Y, Xu Y, Taghipouran R, Li D, Patterson A, Smaill J, Tu Z, Wu D, Ren X, et al. N-(3-Ethynyl-2,4-difluorophenyl)sulfonamide Derivatives as Selective Raf Inhibitors. Acs Medicinal Chemistry Letters. 6: 543-7. PMID 26005530 DOI: 10.1021/Acsmedchemlett.5B00039  0.058
1996 Zhuang X, Silverman AJ, Silver R. Brain mast cell degranulation regulates blood-brain barrier. Journal of Neurobiology. 31: 393-403. PMID 8951099 DOI: 10.1002/(SICI)1097-4695(199612)31:4<393::AID-NEU1>3.0.CO;2-4  0.056
2016 Zhuang X, Ma X, Xue X, Jiang Q, Song L, Dai L, Zhang C, Jin S, Yang K, Ding B, Wang PC, Liang XJ. A Photosensitizer-Loaded DNA Origami Nanosystem for Photodynamic Therapy. Acs Nano. PMID 26950644 DOI: 10.1021/Acsnano.5B07671  0.049
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