Year |
Citation |
Score |
2022 |
Goodwin CM, Waters AM, Klomp JE, Javaid S, Bryant KL, Stalnecker CA, Drizyte-Miller K, Papke B, Yang R, Amparo AM, Ozkan-Dagliyan I, Baldelli E, Calvert V, Pierobon M, Sorrentino JA, et al. Combination Therapies with CDK4/6 Inhibitors to Treat KRAS-mutant Pancreatic Cancer. Cancer Research. PMID 36346366 DOI: 10.1158/0008-5472.CAN-22-0391 |
0.538 |
|
2021 |
Diehl JN, Hibshman PS, Ozkan-Dagliyan I, Goodwin CM, Howard SV, Cox AD, Der CJ. Targeting the ERK mitogen-activated protein kinase cascade for the treatment of KRAS-mutant pancreatic cancer. Advances in Cancer Research. 153: 101-130. PMID 35101228 DOI: 10.1016/bs.acr.2021.07.008 |
0.487 |
|
2020 |
Ozkan-Dagliyan I, Diehl JN, George SD, Schaefer A, Papke B, Klotz-Noack K, Waters AM, Goodwin CM, Gautam P, Pierobon M, Peng S, Gilbert TSK, Lin KH, Dagliyan O, Wennerberg K, et al. Low-Dose Vertical Inhibition of the RAF-MEK-ERK Cascade Causes Apoptotic Death of KRAS Mutant Cancers. Cell Reports. 31: 107764. PMID 32553168 DOI: 10.1016/J.Celrep.2020.107764 |
0.521 |
|
2018 |
Vaseva AV, Blake DR, Gilbert TSK, Ng S, Hostetter G, Azam SH, Ozkan-Dagliyan I, Gautam P, Bryant KL, Pearce KH, Herring LE, Han H, Graves LM, Witkiewicz AK, Knudsen ES, et al. KRAS Suppression-Induced Degradation of MYC Is Antagonized by a MEK5-ERK5 Compensatory Mechanism. Cancer Cell. 34: 807-822.e7. PMID 30423298 DOI: 10.1016/J.Ccell.2018.10.001 |
0.543 |
|
2018 |
Dagliyan O, Krokhotin A, Ozkan-Dagliyan I, Deiters A, Der CJ, Hahn KM, Dokholyan NV. Computational design of chemogenetic and optogenetic split proteins. Nature Communications. 9: 4042. PMID 30279442 DOI: 10.1038/S41467-018-06531-4 |
0.466 |
|
2017 |
Waters AM, Ozkan-Dagliyan I, Vaseva AV, Fer N, Strathern LA, Hobbs GA, Tessier-Cloutier B, Gillette WK, Bagni R, Whiteley GR, Hartley JL, McCormick F, Cox AD, Houghton PJ, Huntsman DG, et al. Evaluation of the selectivity and sensitivity of isoform- and mutation-specific RAS antibodies. Science Signaling. 10. PMID 28951536 DOI: 10.1126/Scisignal.Aao3332 |
0.44 |
|
2014 |
Ye R, Selby CP, Chiou YY, Ozkan-Dagliyan I, Gaddameedhi S, Sancar A. Dual modes of CLOCK:BMAL1 inhibition mediated by Cryptochrome and Period proteins in the mammalian circadian clock. Genes & Development. 28: 1989-98. PMID 25228643 DOI: 10.1101/Gad.249417.114 |
0.467 |
|
2013 |
Ozkan-Dagliyan I, Chiou YY, Ye R, Hassan BH, Ozturk N, Sancar A. Formation of Arabidopsis Cryptochrome 2 photobodies in mammalian nuclei: application as an optogenetic DNA damage checkpoint switch. The Journal of Biological Chemistry. 288: 23244-51. PMID 23833191 DOI: 10.1074/Jbc.M113.493361 |
0.458 |
|
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