David Loane - Publications

Affiliations: 
Anesthesiology University of Maryland School of Medicine, Baltimore, MD, United States 

59 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Henry RJ, Meadows VE, Stoica BA, Faden A, Loane DJ. Longitudinal assessment of sensorimotor function following controlled cortical impact in mice: comparison of beamwalk, rotarod and automated gait analysis tests. Journal of Neurotrauma. PMID 32484024 DOI: 10.1089/neu.2020.7139  1
2020 Abulwerdi G, Stoica BA, Loane DJ, Faden AI. Putative mGluR4 Positive Allosteric Modulators Activate G-Independent Anti-Inflammatory Mechanisms in Microglia. Neurochemistry International. 104770. PMID 32454165 DOI: 10.1016/j.neuint.2020.104770  1
2020 Doran SJ, Henry RJ, Shirey KA, Barrett JP, Ritzel RM, Lai W, Blanco JC, Faden AI, Vogel SN, Loane DJ. Early or Late Bacterial Lung Infection Increases Mortality After Traumatic Brain Injury in Male Mice and Chronically Impairs Monocyte Innate Immune Function. Critical Care Medicine. PMID 32149839 DOI: 10.1097/CCM.0000000000004273  1
2020 Henry RJ, Ritzel RM, Barrett JP, Doran SJ, Jiao Y, Leach JB, Szeto GL, Wu J, Stoica BA, Faden AI, Loane DJ. Microglial depletion with CSF1R inhibitor during chronic phase of experimental traumatic brain injury reduces neurodegeneration and neurological deficits. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 32094203 DOI: 10.1523/JNEUROSCI.2402-19.2020  1
2020 Barrett JP, Henry RJ, Ann Shirey K, Doran SJ, Makarevich OD, Ritzel RR, Meadows VA, Vogel SN, Faden AI, Stoica BA, Loane DJ. Interferon-β plays a detrimental role in experimental traumatic brain injury by enhancing neuroinflammation that drives chronic neurodegeneration. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 32029532 DOI: 10.1523/JNEUROSCI.2516-19.2020  1
2020 Bhat S, Henry RJ, Blanchard AC, Stoica BA, Loane DJ, Faden AI. Enhanced Akt/GSK-3β/CREB signaling mediates the anti-inflammatory actions of mGluR5 positive allosteric modulators in microglia and following traumatic brain injury in male mice. Journal of Neurochemistry. e14954. PMID 31926033 DOI: 10.1111/jnc.14954  1
2019 Ritzel RM, Doran SJ, Glaser EP, Meadows VE, Faden AI, Stoica BA, Loane DJ. Old age increases microglial senescence, exacerbates secondary neuroinflammation, and worsens neurological outcomes after acute traumatic brain injury in mice. Neurobiology of Aging. 77: 194-206. PMID 30904769 DOI: 10.1016/j.neurobiolaging.2019.02.010  1
2019 Stewart W, Allinson K, Al-Sarraj S, Bachmeier C, Barlow K, Belli A, Burns MP, Carson A, Crawford F, Dams-O'Connor K, Diaz-Arrastia R, Dixon CE, Edlow BL, Ferguson S, Fischl B, ... ... Loane DJ, et al. Primum non nocere: a call for balance when reporting on CTE. The Lancet. Neurology. 18: 231-233. PMID 30784550 DOI: 10.1016/S1474-4422(19)30020-1  0.48
2018 Kumar A, Henry R, Stoica B, Loane D, Abulwerdi G, Bhat S, Faden A. Neutral Sphingomyelinase Inhibition Alleviates LPS Induced Microglia Activation and Neuroinflammation after Experimental Traumatic Brain Injury. The Journal of Pharmacology and Experimental Therapeutics. PMID 30563941 DOI: 10.1124/jpet.118.253955  0.88
2018 Doran S, Ritzel R, Glaser E, Henry R, Faden A, Loane DJ. Sex differences in acute neuroinflammation after experimental traumatic brain injury are mediated by infiltrating myeloid cells. Journal of Neurotrauma. PMID 30259790 DOI: 10.1089/neu.2018.6019  0.68
2018 Henry RJ, Doran SJ, Barrett JP, Meadows VE, Sabirzhanov B, Stoica BA, Loane DJ, Faden AI. Inhibition of miR-155 Limits Neuroinflammation and Improves Functional Recovery After Experimental Traumatic Brain Injury in Mice. Neurotherapeutics : the Journal of the American Society For Experimental Neurotherapeutics. PMID 30225790 DOI: 10.1007/s13311-018-0665-9  1
2018 Srivastava S, Katorcha E, Makarava N, Barrett JP, Loane DJ, Baskakov IV. Inflammatory response of microglia to prions is controlled by sialylation of PrP. Scientific Reports. 8: 11326. PMID 30054538 DOI: 10.1038/s41598-018-29720-z  0.44
2018 Srivastava S, Katorcha E, Makarava N, Barrett JP, Loane DJ, Baskakov IV. Inflammatory response of microglia to prions is controlled by sialylation of PrP. Scientific Reports. 8: 11326. PMID 30054538 DOI: 10.1038/s41598-018-29720-z  0.44
2018 Loane DJ, Faden AI. Traumatic meningeal injury and repair mechanisms. Nature Immunology. 19: 431-432. PMID 29670238 DOI: 10.1038/s41590-018-0093-3  1
2018 Ritzel R, Doran S, Barrett J, Henry R, Ma E, Faden A, Loane DJ. Chronic Alterations in Systemic Immune Function After Traumatic Brain Injury. Journal of Neurotrauma. PMID 29421977 DOI: 10.1089/neu.2017.5399  0.68
2017 Fe Lanfranco M, Loane DJ, Mocchetti I, Burns MP, Villapol S. Combination of Fluorescent in situ Hybridization (FISH) and Immunofluorescence Imaging for Detection of Cytokine Expression in Microglia/Macrophage Cells. Bio-Protocol. 7. PMID 29238736 DOI: 10.21769/BioProtoc.2608  0.48
2017 Ma EL, Smith AD, Desai N, Cheung L, Hanscom M, Stoica BA, Loane DJ, Shea-Donohue T, Faden AI. Bidirectional Brain-Gut Interactions and Chronic Pathological Changes after Traumatic Brain Injury in Mice. Brain, Behavior, and Immunity. PMID 28676351 DOI: 10.1016/j.bbi.2017.06.018  1
2017 Villapol S, Loane DJ, Burns MP. Sexual dimorphism in the inflammatory response to traumatic brain injury. Glia. PMID 28608978 DOI: 10.1002/glia.23171  0.48
2017 Barrett JP, Henry RJ, Villapol S, Stoica BA, Kumar A, Burns MP, Faden AI, Loane DJ. NOX2 deficiency alters macrophage phenotype through an IL-10/STAT3 dependent mechanism: implications for traumatic brain injury. Journal of Neuroinflammation. 14: 65. PMID 28340575 DOI: 10.1186/s12974-017-0843-4  1
2017 Kumar A, Stoica BA, Loane DJ, Yang M, Abulwerdi G, Khan N, Kumar A, Thom SR, Faden AI. Microglial-derived microparticles mediate neuroinflammation after traumatic brain injury. Journal of Neuroinflammation. 14: 47. PMID 28292310 DOI: 10.1186/s12974-017-0819-4  1
2016 Kumar A, Barrett JP, Alvarez-Croda DM, Stoica BA, Faden AI, Loane DJ. NOX2 drives M1-like microglial/macrophage activation and neurodegeneration following experimental traumatic brain injury. Brain, Behavior, and Immunity. PMID 27477920 DOI: 10.1016/j.bbi.2016.07.158  1
2016 Wu J, Zhao Z, Kumar A, Lipinski MM, Loane DJ, Stoica BA, Faden AI. ER stress and disrupted neurogenesis in the brain are associated with cognitive impairment and depressive-like behavior after spinal cord injury. Journal of Neurotrauma. PMID 27050417 DOI: 10.1089/neu.2015.4348  1
2015 Kumar A, Alvarez-Croda DM, Stoica BA, Faden AI, Loane DJ. Microglial/macrophage polarization dynamics following traumatic brain injury. Journal of Neurotrauma. PMID 26486881 DOI: 10.1089/neu.2015.4268  1
2015 Loane DJ, Kumar A. Microglia in the TBI brain: The good, the bad, and the dysregulated. Experimental Neurology. PMID 26342753 DOI: 10.1016/j.expneurol.2015.08.018  0.72
2015 Kabadi SV, Stoica BA, Zimmer DB, Afanador L, Duffy KB, Loane DJ, Faden AI. S100B inhibition reduces behavioral and pathologic changes in experimental traumatic brain injury. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. PMID 26154869 DOI: 10.1038/jcbfm.2015.165  1
2015 Faden AI, Wu J, Stoica BA, Loane DJ. Progressive inflammation-mediated neurodegeneration after traumatic brain or spinal cord injury. British Journal of Pharmacology. PMID 25939377 DOI: 10.1111/bph.13179  1
2015 Loane DJ, Stoica BA, Faden AI. Neuroprotection for traumatic brain injury. Handbook of Clinical Neurology. 127: 343-66. PMID 25702227 DOI: 10.1016/B978-0-444-52892-6.00022-2  1
2015 Faden AI, Loane DJ. Chronic neurodegeneration after traumatic brain injury: Alzheimer disease, chronic traumatic encephalopathy, or persistent neuroinflammation? Neurotherapeutics : the Journal of the American Society For Experimental Neurotherapeutics. 12: 143-50. PMID 25421001 DOI: 10.1007/s13311-014-0319-5  1
2014 Loane DJ, Stoica BA, Tchantchou F, Kumar A, Barrett JP, Akintola T, Xue F, Conn PJ, Faden AI. Novel mGluR5 positive allosteric modulator improves functional recovery, attenuates neurodegeneration, and alters microglial polarization after experimental traumatic brain injury. Neurotherapeutics : the Journal of the American Society For Experimental Neurotherapeutics. 11: 857-69. PMID 25096154 DOI: 10.1007/s13311-014-0298-6  1
2014 Sabirzhanov B, Zhao Z, Stoica BA, Loane DJ, Wu J, Borroto C, Dorsey SG, Faden AI. Downregulation of miR-23a and miR-27a following experimental traumatic brain injury induces neuronal cell death through activation of proapoptotic Bcl-2 proteins. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 10055-71. PMID 25057207 DOI: 10.1523/JNEUROSCI.1260-14.2014  1
2014 Stoica BA, Loane DJ, Zhao Z, Kabadi SV, Hanscom M, Byrnes KR, Faden AI. PARP-1 inhibition attenuates neuronal loss, microglia activation and neurological deficits after traumatic brain injury. Journal of Neurotrauma. 31: 758-72. PMID 24476502 DOI: 10.1089/neu.2013.3194  1
2014 Kabadi SV, Stoica BA, Loane DJ, Luo T, Faden AI. CR8, a novel inhibitor of CDK, limits microglial activation, astrocytosis, neuronal loss, and neurologic dysfunction after experimental traumatic brain injury. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 34: 502-13. PMID 24398934 DOI: 10.1038/jcbfm.2013.228  1
2014 Loane DJ, Kumar A, Stoica BA, Cabatbat R, Faden AI. Progressive neurodegeneration after experimental brain trauma: association with chronic microglial activation. Journal of Neuropathology and Experimental Neurology. 73: 14-29. PMID 24335533 DOI: 10.1097/NEN.0000000000000021  1
2013 Zhao Z, Faden AI, Loane DJ, Lipinski MM, Sabirzhanov B, Stoica BA. Neuroprotective effects of geranylgeranylacetone in experimental traumatic brain injury. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 33: 1897-908. PMID 23942364 DOI: 10.1038/jcbfm.2013.144  1
2013 Winston CN, Chellappa D, Wilkins T, Barton DJ, Washington PM, Loane DJ, Zapple DN, Burns MP. Controlled cortical impact results in an extensive loss of dendritic spines that is not mediated by injury-induced amyloid-beta accumulation. Journal of Neurotrauma. 30: 1966-72. PMID 23879560 DOI: 10.1089/neu.2013.2960  1
2013 Piao CS, Stoica BA, Wu J, Sabirzhanov B, Zhao Z, Cabatbat R, Loane DJ, Faden AI. Late exercise reduces neuroinflammation and cognitive dysfunction after traumatic brain injury. Neurobiology of Disease. 54: 252-63. PMID 23313314 DOI: 10.1016/j.nbd.2012.12.017  1
2013 Kumar A, Stoica BA, Sabirzhanov B, Burns MP, Faden AI, Loane DJ. Traumatic brain injury in aged animals increases lesion size and chronically alters microglial/macrophage classical and alternative activation states. Neurobiology of Aging. 34: 1397-411. PMID 23273602 DOI: 10.1016/j.neurobiolaging.2012.11.013  1
2013 Loane DJ, Stoica BA, Byrnes KR, Jeong W, Faden AI. Activation of mGluR5 and inhibition of NADPH oxidase improves functional recovery after traumatic brain injury. Journal of Neurotrauma. 30: 403-12. PMID 23199080 DOI: 10.1089/neu.2012.2589  1
2012 Zhao Z, Loane DJ, Murray MG, Stoica BA, Faden AI. Comparing the predictive value of multiple cognitive, affective, and motor tasks after rodent traumatic brain injury. Journal of Neurotrauma. 29: 2475-89. PMID 22924665 DOI: 10.1089/neu.2012.2511  1
2012 Kumar A, Loane DJ. Neuroinflammation after traumatic brain injury: opportunities for therapeutic intervention. Brain, Behavior, and Immunity. 26: 1191-201. PMID 22728326 DOI: 10.1016/j.bbi.2012.06.008  0.72
2012 Loane DJ, Stoica BA, Faden AI. Metabotropic glutamate receptor-mediated signaling in neuroglia. Wiley Interdisciplinary Reviews. Membrane Transport and Signaling. 1: 136-150. PMID 22662309 DOI: 10.1002/wmts.30  1
2012 Piao CS, Loane DJ, Stoica BA, Li S, Hanscom M, Cabatbat R, Blomgren K, Faden AI. Combined inhibition of cell death induced by apoptosis inducing factor and caspases provides additive neuroprotection in experimental traumatic brain injury. Neurobiology of Disease. 46: 745-58. PMID 22426396 DOI: 10.1016/j.nbd.2012.03.018  1
2012 Byrnes KR, Loane DJ, Stoica BA, Zhang J, Faden AI. Delayed mGluR5 activation limits neuroinflammation and neurodegeneration after traumatic brain injury. Journal of Neuroinflammation. 9: 43. PMID 22373400 DOI: 10.1186/1742-2094-9-43  1
2012 Kabadi SV, Stoica BA, Hanscom M, Loane DJ, Kharebava G, Murray Ii MG, Cabatbat RM, Faden AI. CR8, a selective and potent CDK inhibitor, provides neuroprotection in experimental traumatic brain injury. Neurotherapeutics : the Journal of the American Society For Experimental Neurotherapeutics. 9: 405-21. PMID 22167461 DOI: 10.1007/s13311-011-0095-4  1
2012 Kabadi SV, Stoica BA, Loane DJ, Byrnes KR, Hanscom M, Cabatbat RM, Tan MT, Faden AI. Cyclin D1 gene ablation confers neuroprotection in traumatic brain injury. Journal of Neurotrauma. 29: 813-27. PMID 21895533 DOI: 10.1089/neu.2011.1980  1
2012 Kabadi SV, Stoica BA, Byrnes KR, Hanscom M, Loane DJ, Faden AI. Selective CDK inhibitor limits neuroinflammation and progressive neurodegeneration after brain trauma. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 32: 137-49. PMID 21829212 DOI: 10.1038/jcbfm.2011.117  1
2011 Loane DJ, Washington PM, Vardanian L, Pocivavsek A, Hoe HS, Duff KE, Cernak I, Rebeck GW, Faden AI, Burns MP. Modulation of ABCA1 by an LXR agonist reduces β-amyloid levels and improves outcome after traumatic brain injury. Journal of Neurotrauma. 28: 225-36. PMID 21175399 DOI: 10.1089/neu.2010.1595  1
2010 Loane DJ, Faden AI. Neuroprotection for traumatic brain injury: translational challenges and emerging therapeutic strategies. Trends in Pharmacological Sciences. 31: 596-604. PMID 21035878 DOI: 10.1016/j.tips.2010.09.005  1
2010 Loane DJ, Byrnes KR. Role of microglia in neurotrauma. Neurotherapeutics : the Journal of the American Society For Experimental Neurotherapeutics. 7: 366-77. PMID 20880501 DOI: 10.1016/j.nurt.2010.07.002  1
2009 Byrnes KR, Stoica B, Riccio A, Pajoohesh-Ganji A, Loane DJ, Faden AI. Activation of metabotropic glutamate receptor 5 improves recovery after spinal cord injury in rodents. Annals of Neurology. 66: 63-74. PMID 19670441 DOI: 10.1002/ana.21673  1
2009 Loane DJ, Stoica BA, Pajoohesh-Ganji A, Byrnes KR, Faden AI. Activation of metabotropic glutamate receptor 5 modulates microglial reactivity and neurotoxicity by inhibiting NADPH oxidase. The Journal of Biological Chemistry. 284: 15629-39. PMID 19364772 DOI: 10.1074/jbc.M806139200  1
2009 Loane DJ, Pocivavsek A, Moussa CE, Thompson R, Matsuoka Y, Faden AI, Rebeck GW, Burns MP. Amyloid precursor protein secretases as therapeutic targets for traumatic brain injury. Nature Medicine. 15: 377-9. PMID 19287391 DOI: 10.1038/nm.1940  1
2009 Byrnes KR, Loane DJ, Faden AI. Metabotropic glutamate receptors as targets for multipotential treatment of neurological disorders. Neurotherapeutics : the Journal of the American Society For Experimental Neurotherapeutics. 6: 94-107. PMID 19110202 DOI: 10.1016/j.nurt.2008.10.038  1
2009 Byrnes KR, Stoica B, Loane DJ, Riccio A, Davis MI, Faden AI. Metabotropic glutamate receptor 5 activation inhibits microglial associated inflammation and neurotoxicity. Glia. 57: 550-60. PMID 18816644 DOI: 10.1002/glia.20783  1
2009 Loane DJ, Deighan BF, Clarke RM, Griffin RJ, Lynch AM, Lynch MA. Interleukin-4 mediates the neuroprotective effects of rosiglitazone in the aged brain. Neurobiology of Aging. 30: 920-31. PMID 17950491 DOI: 10.1016/j.neurobiolaging.2007.09.001  1
2007 Minogue AM, Lynch AM, Loane DJ, Herron CE, Lynch MA. Modulation of amyloid-beta-induced and age-associated changes in rat hippocampus by eicosapentaenoic acid. Journal of Neurochemistry. 103: 914-26. PMID 17711425 DOI: 10.1111/j.1471-4159.2007.04848.x  1
2007 Loane DJ, Lima PA, Marrion NV. Co-assembly of N-type Ca2+ and BK channels underlies functional coupling in rat brain. Journal of Cell Science. 120: 985-95. PMID 17311846 DOI: 10.1242/jcs.03399  1
2007 Lynch AM, Loane DJ, Minogue AM, Clarke RM, Kilroy D, Nally RE, Roche OJ, O'Connell F, Lynch MA. Eicosapentaenoic acid confers neuroprotection in the amyloid-beta challenged aged hippocampus. Neurobiology of Aging. 28: 845-55. PMID 16714069 DOI: 10.1016/j.neurobiolaging.2006.04.006  1
2006 Loane DJ, Hicks GA, Perrino BA, Marrion NV. Inhibition of BKCa channel activity by association with calcineurin in rat brain European Journal of Neuroscience. 24: 433-441. PMID 16903851 DOI: 10.1111/j.1460-9568.2006.04931.x  1
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