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David J. Barton, MD - Publications

Affiliations: 
Department of Emergency Medicine University of Pittsburgh School of Medicine, Pittsburgh, PA, United States 
Area:
Traumatic brain injury, emergency medicine, wilderness medicine, prehospital medicine
Website:
https://www.linkedin.com/in/bartond/
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51 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Barton DJ, Kumar RG, Schuster AA, Juengst SB, Oh BM, Wagner AK. Acute Cortisol Profile Associations With Cognitive Impairment After Severe Traumatic Brain Injury. Neurorehabilitation and Neural Repair. 15459683211048771. PMID 34689657 DOI: 10.1177/15459683211048771  0.505
2020 Ancar R, Li Y, Kindler E, Cooper DA, Ransom M, Thiel V, Weiss SR, Hesselberth JR, Barton DJ. Physiologic RNA Targets and Refined Sequence Specificity of Coronavirus EndoU. Rna (New York, N.Y.). PMID 32989044 DOI: 10.1261/rna.076604.120  0.364
2020 Kempf BJ, Watkins CL, Peersen OB, Barton DJ. An Extended Primer Grip of Picornavirus Polymerase Facilitates Sexual RNA Replication Mechanisms. Journal of Virology. PMID 32522851 DOI: 10.1128/Jvi.00835-20  0.424
2020 Watkins CL, Kempf BJ, Beaucourt S, Barton DJ, Peersen OB. Picornaviral polymerase domain exchanges reveal a modular basis for distinct biochemical activities of viral RNA-dependent RNA polymerases. The Journal of Biological Chemistry. PMID 32493771 DOI: 10.1074/Jbc.Ra120.013906  0.39
2020 Vijapur S, Yang Z, Barton D, Vaughan L, Awan N, Kumar R, Oh BM, Berga S, Wang KKW, Wagner AK. Anti-pituitary and anti-hypothalamus autoantibody associations with inflammation and hypogonadotropic hypogonadism in men with traumatic brain injury. Journal of Neurotrauma. PMID 32111134 DOI: 10.1089/Neu.2019.6780  0.537
2019 Kempf BJ, Watkins CL, Peersen OB, Barton DJ. Picornavirus RNA Recombination Counteracts Error Catastrophe. Journal of Virology. PMID 31068422 DOI: 10.1128/Jvi.00652-19  0.442
2018 Main BS, Villapol S, Sloley SS, Barton DJ, Parsadanian M, Agbaegbu C, Stefos K, McCann MS, Washington PM, Rodriguez OC, Burns MP. Apolipoprotein E4 impairs spontaneous blood brain barrier repair following traumatic brain injury. Molecular Neurodegeneration. 13: 17. PMID 29618365 DOI: 10.1186/S13024-018-0249-5  0.588
2016 Kempf BJ, Peersen OB, Barton DJ. Poliovirus Polymerase Leu420 Facilitates RNA Recombination and Ribavirin Resistance. Journal of Virology. PMID 27412593 DOI: 10.1128/Jvi.00078-16  0.449
2016 Barton DJ, Tift FW, Cournoyer LE, Vieth JT, Hudson KB. Acute Alcohol Use and Injury Patterns in Young Adult Prehospital Patients. Prehospital Emergency Care : Official Journal of the National Association of Ems Physicians and the National Association of State Ems Directors. 20: 206-11. PMID 27002348 DOI: 10.3109/10903127.2015.1076101  0.316
2016 Winston CN, Noël A, Neustadtl A, Parsadanian M, Barton DJ, Chellappa D, Wilkins TE, Alikhani AD, Zapple DN, Villapol S, Planel E, Burns MP. Dendritic Spine Loss and Chronic White Matter Inflammation in a Mouse Model of Highly Repetitive Head Trauma. The American Journal of Pathology. PMID 26857506 DOI: 10.1016/J.Ajpath.2015.11.006  0.592
2016 Clingan J, Eckard S, Cooper D, Ramos H, Guillen J, Canard B, Gale M, Hesselberth J, Barton D, Stetson D. Abstract B133: Regulation of antiviral immune responses by RNase L Cancer Immunology Research. 4. DOI: 10.1158/2326-6066.Imm2016-B133  0.407
2015 Barton DJ, Kumar RG, McCullough EH, Galang G, Arenth PM, Berga SL, Wagner AK. Persistent Hypogonadotropic Hypogonadism in Men After Severe Traumatic Brain Injury: Temporal Hormone Profiles and Outcome Prediction. The Journal of Head Trauma Rehabilitation. PMID 26360007 DOI: 10.1097/Htr.0000000000000188  0.547
2015 Kempf BJ, Barton DJ. Picornavirus RNA polyadenylation by 3D(pol), the viral RNA-dependent RNA polymerase. Virus Research. 206: 3-11. PMID 25559071 DOI: 10.1016/J.Virusres.2014.12.030  0.433
2015 Cooper DA, Banerjee S, Chakrabarti A, García-Sastre A, Hesselberth JR, Silverman RH, Barton DJ. RNase L targets distinct sites in influenza A virus RNAs. Journal of Virology. 89: 2764-76. PMID 25540362 DOI: 10.1128/Jvi.02953-14  0.426
2014 Cooper DA, Jha BK, Silverman RH, Hesselberth JR, Barton DJ. Ribonuclease L and metal-ion-independent endoribonuclease cleavage sites in host and viral RNAs. Nucleic Acids Research. 42: 5202-16. PMID 24500209 DOI: 10.1093/Nar/Gku118  0.426
2013 Winston CN, Chellappa D, Wilkins T, Barton DJ, Washington PM, Loane DJ, Zapple DN, Burns MP. Controlled cortical impact results in an extensive loss of dendritic spines that is not mediated by injury-induced amyloid-beta accumulation. Journal of Neurotrauma. 30: 1966-72. PMID 23879560 DOI: 10.1089/Neu.2013.2960  0.597
2013 Kempf BJ, Kelly MM, Springer CL, Peersen OB, Barton DJ. Structural features of a picornavirus polymerase involved in the polyadenylation of viral RNA. Journal of Virology. 87: 5629-44. PMID 23468507 DOI: 10.1128/Jvi.02590-12  0.453
2012 Schuessler A, Funk A, Lazear HM, Cooper DA, Torres S, Daffis S, Jha BK, Kumagai Y, Takeuchi O, Hertzog P, Silverman R, Akira S, Barton DJ, Diamond MS, Khromykh AA. West Nile virus noncoding subgenomic RNA contributes to viral evasion of the type I interferon-mediated antiviral response. Journal of Virology. 86: 5708-18. PMID 22379089 DOI: 10.1128/Jvi.00207-12  0.338
2012 Kortus MG, Kempf BJ, Haworth KG, Barton DJ, Peersen OB. A template RNA entry channel in the fingers domain of the poliovirus polymerase. Journal of Molecular Biology. 417: 263-78. PMID 22321798 DOI: 10.1016/J.Jmb.2012.01.049  0.459
2012 Shimakami T, Yamane D, Jangra RK, Kempf BJ, Spaniel C, Barton DJ, Lemon SM. Stabilization of hepatitis C virus RNA by an Ago2-miR-122 complex. Proceedings of the National Academy of Sciences of the United States of America. 109: 941-6. PMID 22215596 DOI: 10.1073/Pnas.1112263109  0.374
2010 Malathi K, Saito T, Crochet N, Barton DJ, Gale M, Silverman RH. RNase L releases a small RNA from HCV RNA that refolds into a potent PAMP. Rna (New York, N.Y.). 16: 2108-19. PMID 20833746 DOI: 10.1261/Rna.2244210  0.426
2010 Hobdey SE, Kempf BJ, Steil BP, Barton DJ, Peersen OB. Poliovirus polymerase residue 5 plays a critical role in elongation complex stability. Journal of Virology. 84: 8072-84. PMID 20534858 DOI: 10.1128/Jvi.02147-09  0.375
2010 Steil BP, Kempf BJ, Barton DJ. Poly(A) at the 3' end of positive-strand RNA and VPg-linked poly(U) at the 5' end of negative-strand RNA are reciprocal templates during replication of poliovirus RNA. Journal of Virology. 84: 2843-58. PMID 20071574 DOI: 10.1128/Jvi.02620-08  0.454
2010 Malathi K, Saito T, Crochet N, Barton DJ, Gale M, Silverman RH. PS3-09 An RNase L mediated cleavage product of hepatitis C virus RNA requires a 3′- Cytokine. 52: 84. DOI: 10.1016/J.Cyto.2010.07.348  0.401
2009 Steil BP, Barton DJ. Conversion of VPg into VPgpUpUOH before and during poliovirus negative-strand RNA synthesis. Journal of Virology. 83: 12660-70. PMID 19812161 DOI: 10.1128/Jvi.01676-08  0.461
2009 Steil BP, Barton DJ. Cis-active RNA elements (CREs) and picornavirus RNA replication. Virus Research. 139: 240-52. PMID 18773930 DOI: 10.1016/J.Virusres.2008.07.027  0.46
2008 Townsend HL, Jha BK, Silverman RH, Barton DJ. A putative loop E motif and an H-H kissing loop interaction are conserved and functional features in a group C enterovirus RNA that inhibits ribonuclease L. Rna Biology. 5: 263-72. PMID 19088502 DOI: 10.4161/Rna.7165  0.426
2008 Steil BP, Barton DJ. Poliovirus cis-acting replication element-dependent VPg Uridylylation lowers the Km of the initiating nucleoside triphosphate for viral RNA replication. Journal of Virology. 82: 9400-8. PMID 18653453 DOI: 10.1128/Jvi.00427-08  0.46
2008 Townsend HL, Jha BK, Han JQ, Maluf NK, Silverman RH, Barton DJ. A viral RNA competitively inhibits the antiviral endoribonuclease domain of RNase L. Rna (New York, N.Y.). 14: 1026-36. PMID 18426919 DOI: 10.1261/Rna.958908  0.428
2008 Kempf BJ, Barton DJ. Poly(rC) binding proteins and the 5' cloverleaf of uncapped poliovirus mRNA function during de novo assembly of polysomes. Journal of Virology. 82: 5835-46. PMID 18400854 DOI: 10.1128/Jvi.01513-07  0.404
2007 Washenberger CL, Han JQ, Kechris KJ, Jha BK, Silverman RH, Barton DJ. Hepatitis C virus RNA: dinucleotide frequencies and cleavage by RNase L. Virus Research. 130: 85-95. PMID 17604869 DOI: 10.1016/J.Virusres.2007.05.020  0.363
2007 Han JQ, Townsend HL, Jha BK, Paranjape JM, Silverman RH, Barton DJ. A phylogenetically conserved RNA structure in the poliovirus open reading frame inhibits the antiviral endoribonuclease RNase L. Journal of Virology. 81: 5561-72. PMID 17344297 DOI: 10.1128/Jvi.01857-06  0.397
2006 Jurgens CK, Barton DJ, Sharma N, Morasco BJ, Ogram SA, Flanegan JB. 2Apro is a multifunctional protein that regulates the stability, translation and replication of poliovirus RNA. Virology. 345: 346-57. PMID 16297952 DOI: 10.1016/J.Virol.2005.09.067  0.373
2004 Han JQ, Wroblewski G, Xu Z, Silverman RH, Barton DJ. Sensitivity of hepatitis C virus RNA to the antiviral enzyme ribonuclease L is determined by a subset of efficient cleavage sites. Journal of Interferon & Cytokine Research : the Official Journal of the International Society For Interferon and Cytokine Research. 24: 664-76. PMID 15684820 DOI: 10.1089/Jir.2004.24.664  0.403
2004 Murray KE, Steil BP, Roberts AW, Barton DJ. Replication of poliovirus RNA with complete internal ribosome entry site deletions. Journal of Virology. 78: 1393-402. PMID 14722294 DOI: 10.1128/Jvi.78.3.1393-1402.2004  0.471
2003 Murray KE, Barton DJ. Poliovirus CRE-dependent VPg uridylylation is required for positive-strand RNA synthesis but not for negative-strand RNA synthesis. Journal of Virology. 77: 4739-50. PMID 12663781 DOI: 10.1128/Jvi.77.8.4739-4750.2003  0.459
2002 Pathak HB, Ghosh SK, Roberts AW, Sharma SD, Yoder JD, Arnold JJ, Gohara DW, Barton DJ, Paul AV, Cameron CE. Structure-function relationships of the RNA-dependent RNA polymerase from poliovirus (3Dpol). A surface of the primary oligomerization domain functions in capsid precursor processing and VPg uridylylation. The Journal of Biological Chemistry. 277: 31551-62. PMID 12077141 DOI: 10.1074/Jbc.M204408200  0.372
2001 Lyons T, Murray KE, Roberts AW, Barton DJ. Poliovirus 5'-terminal cloverleaf RNA is required in cis for VPg uridylylation and the initiation of negative-strand RNA synthesis. Journal of Virology. 75: 10696-708. PMID 11602711 DOI: 10.1128/Jvi.75.22.10696-10708.2001  0.472
2001 Murray KE, Roberts AW, Barton DJ. Poly(rC) binding proteins mediate poliovirus mRNA stability. Rna (New York, N.Y.). 7: 1126-41. PMID 11497431 DOI: 10.1017/S1355838201010044  0.434
2001 Barton DJ, O'Donnell BJ, Flanegan JB. 5' cloverleaf in poliovirus RNA is a cis-acting replication element required for negative-strand synthesis. The Embo Journal. 20: 1439-48. PMID 11250909 DOI: 10.1093/Emboj/20.6.1439  0.473
1999 Barton DJ, Morasco BJ, Flanegan JB. Translating ribosomes inhibit poliovirus negative-strand RNA synthesis Journal of Virology. 73: 10104-10112. PMID 10559325 DOI: 10.1128/Jvi.73.12.10104-10112.1999  0.463
1997 Barton DJ, Flanegan JB. Synchronous replication of poliovirus RNA: initiation of negative-strand RNA synthesis requires the guanidine-inhibited activity of protein 2C. Journal of Virology. 71: 8482-9. PMID 9343205 DOI: 10.1128/Jvi.71.11.8482-8489.1997  0.459
1997 Tang RS, Barton DJ, Flanegan JB, Kirkegaard K. Poliovirus RNA recombination in cell-free extracts. Rna (New York, N.Y.). 3: 624-33. PMID 9174097  0.331
1996 Barton DJ, Morasco BJ, Eisner-Smerage L, Collis PS, Diamond SE, Hewlett MJ, Merchant MA, O'Donnell BJ, Flanegan JB. Poliovirus RNA polymerase mutation 3D-M394T results in a temperature-sensitive defect in RNA synthesis Virology. 217: 459-469. PMID 8610437 DOI: 10.1006/Viro.1996.0140  0.425
1995 Barton DJ, Black EP, Flanegan JB. Complete replication of poliovirus in vitro: preinitiation RNA replication complexes require soluble cellular factors for the synthesis of VPg-linked RNA. Journal of Virology. 69: 5516-27. PMID 7636997 DOI: 10.1128/Jvi.69.9.5516-5527.1995  0.461
1993 Barton DJ, Flanegan JB. Coupled translation and replication of poliovirus RNA in vitro: synthesis of functional 3D polymerase and infectious virus. Journal of Virology. 67: 822-31. PMID 8380467 DOI: 10.1128/Jvi.67.2.822-831.1993  0.433
1993 Barton D, Allen M, Finlay D, Belton I. Evaluation of whiplash injuries by technetium 99m isotope scanning. Emergency Medicine Journal. 10: 197-202. PMID 8216594 DOI: 10.1136/Emj.10.3.197  0.34
1992 Collis PS, O'Donnell BJ, Barton DJ, Rogers JA, Flanegan JB. Replication of poliovirus RNA and subgenomic RNA transcripts in transfected cells. Journal of Virology. 66: 6480-8. PMID 1328676 DOI: 10.1128/Jvi.66.11.6480-6488.1992  0.467
1991 Barton DJ, Sawicki SG, Sawicki DL. Solubilization and immunoprecipitation of alphavirus replication complexes Journal of Virology. 65: 1496-1506. PMID 1847467 DOI: 10.1128/Jvi.65.3.1496-1506.1991  0.402
1991 Phair IC, Barton DJ, Allen MJ, Barnes MR. Preventable deaths after head injury: a clinical audit of performance. Injury. 22: 353-6. PMID 1806492 DOI: 10.1016/0020-1383(91)90092-S  0.312
1988 Barton DJ, Sawicki SG, Sawicki DL. Demonstration in vitro of temperature-sensitive elongation of RNA in Sindbis virus mutant ts6 Journal of Virology. 62: 3597-3602. PMID 3418782 DOI: 10.1128/Jvi.62.10.3597-3602.1988  0.403
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