| Year |
Citation |
Score |
| 2024 |
Sexton JA, Potchernikov T, Bibeau JP, Casanova-Sepúlveda G, Cao W, Lou HJ, Boggon TJ, De La Cruz EM, Turk BE. Distinct functional constraints driving conservation of the cofilin N-terminal regulatory tail. Nature Communications. 15: 1426. PMID 38365893 DOI: 10.1038/s41467-024-45878-9 |
0.377 |
|
| 2023 |
Torres Robles J, Lou HJ, Shi G, Pan PL, Turk BE. Linear motif specificity in signaling through p38α and ERK2 mitogen-activated protein kinases. Proceedings of the National Academy of Sciences of the United States of America. 120: e2316599120. PMID 37988460 DOI: 10.1073/pnas.2316599120 |
0.431 |
|
| 2023 |
Sexton JA, Potchernikov T, Casanova-Sepúlveda G, Cao W, Lou HJ, Boggon TJ, De La Cruz EM, Turk BE. Distinct functional constraints driving conservation of the cofilin N-terminal regulatory tail. Biorxiv : the Preprint Server For Biology. PMID 37425676 DOI: 10.1101/2023.06.30.547189 |
0.375 |
|
| 2023 |
Zhou W, Li W, Wang S, Salovska B, Hu Z, Tao B, Di Y, Punyamurtula U, Turk BE, Sessa WC, Liu Y. An optogenetic-phosphoproteomic study reveals dynamic Akt1 signaling profiles in endothelial cells. Nature Communications. 14: 3803. PMID 37365174 DOI: 10.1038/s41467-023-39514-1 |
0.34 |
|
| 2023 |
Johnson JL, Yaron TM, Huntsman EM, Kerelsky A, Song J, Regev A, Lin TY, Liberatore K, Cizin DM, Cohen BM, Vasan N, Ma Y, Krismer K, Robles JT, van de Kooij B, ... ... Turk BE, et al. An atlas of substrate specificities for the human serine/threonine kinome. Nature. PMID 36631611 DOI: 10.1038/s41586-022-05575-3 |
0.761 |
|
| 2023 |
Shi G, Song C, Torres Robles J, Salichos L, Lou HJ, Lam TT, Gerstein M, Turk BE. Proteome-wide screening for mitogen-activated protein kinase docking motifs and interactors. Science Signaling. 16: eabm5518. PMID 36626580 DOI: 10.1126/scisignal.abm5518 |
0.579 |
|
| 2022 |
Simon B, Lou HJ, Huet-Calderwood C, Shi G, Boggon TJ, Turk BE, Calderwood DA. Tousled-like kinase 2 targets ASF1 histone chaperones through client mimicry. Nature Communications. 13: 749. PMID 35136069 DOI: 10.1038/s41467-022-28427-0 |
0.383 |
|
| 2021 |
Schiapparelli P, Pirman NL, Mohler K, Miranda-Herrera PA, Zarco N, Kilic O, Miller C, Shah SR, Rogulina S, Hungerford W, Abriola L, Hoyer D, Turk BE, Guerrero-Cázares H, Isaacs FJ, et al. Phosphorylated WNK kinase networks in recoded bacteria recapitulate physiological function. Cell Reports. 36: 109416. PMID 34289367 DOI: 10.1016/j.celrep.2021.109416 |
0.393 |
|
| 2021 |
Cho E, Lou HJ, Kuruvilla L, Calderwood DA, Turk BE. PPP6C negatively regulates oncogenic ERK signaling through dephosphorylation of MEK. Cell Reports. 34: 108928. PMID 33789117 DOI: 10.1016/j.celrep.2021.108928 |
0.337 |
|
| 2020 |
Komolov KE, Sulon SM, Bhardwaj A, van Keulen SC, Duc NM, Laurinavichyute DK, Lou HJ, Turk BE, Chung KY, Dror RO, Benovic JL. Structure of a GRK5-Calmodulin Complex Reveals Molecular Mechanism of GRK Activation and Substrate Targeting. Molecular Cell. PMID 33321095 DOI: 10.1016/j.molcel.2020.11.026 |
0.319 |
|
| 2020 |
Terekhov SS, Mokrushina YA, Nazarov AS, Zlobin A, Zalevsky A, Bourenkov G, Golovin A, Belogurov A, Osterman IA, Kulikova AA, Mitkevich VA, Lou HJ, Turk BE, Wilmanns M, Smirnov IV, et al. A kinase bioscavenger provides antibiotic resistance by extremely tight substrate binding. Science Advances. 6: eaaz9861. PMID 32637600 DOI: 10.1126/Sciadv.Aaz9861 |
0.331 |
|
| 2020 |
Chetty AK, Sexton JA, Hak Ha B, Turk BE, Boggon TJ. Recognition of physiological phosphorylation sites by p21-activated kinase 4. Journal of Structural Biology. 107553. PMID 32585314 DOI: 10.1016/j.jsb.2020.107553 |
0.377 |
|
| 2020 |
Ayuso PT, An E, Ritt D, Nyswaner K, Specht S, Liang R, Das S, Andresson T, Turk B, Morrison D, Brognard J. The protein kinase TNIK: a novel druggable target in Lung Squamous Cell Carcinoma with 3q amplification. The Faseb Journal. 34: 1-1. DOI: 10.1096/Fasebj.2020.34.S1.03326 |
0.313 |
|
| 2019 |
Sang D, Pinglay S, Wiewiora RP, Selvan ME, Lou HJ, Chodera JD, Turk BE, Gümüş ZH, Holt LJ. Ancestral reconstruction reveals mechanisms of ERK regulatory evolution. Elife. 8. PMID 31407663 DOI: 10.7554/Elife.38805 |
0.346 |
|
| 2019 |
Santini CC, Longden J, Schoof EM, Simpson CD, Jeschke GR, Creixell P, Kim J, Wu X, Turk BE, Rosen N, Poulikakos PI, Linding R. Global view of the RAF-MEK-ERK module and its immediate downstream effectors. Scientific Reports. 9: 10865. PMID 31350469 DOI: 10.1038/S41598-019-47245-X |
0.409 |
|
| 2019 |
van de Kooij B, Creixell P, van Vlimmeren A, Joughin B, Miller CJ, Haider N, Simpson CD, Linding R, Stambolic V, Turk BE, Yaffe MB. Comprehensive substrate specificity profiling of the human Nek kinome reveals unexpected signaling outputs. Elife. 8. PMID 31124786 DOI: 10.7554/Elife.44635 |
0.589 |
|
| 2019 |
Miller CJ, Lou HJ, Simpson C, van de Kooij B, Ha BH, Fisher OS, Pirman NL, Boggon TJ, Rinehart J, Yaffe MB, Linding R, Turk BE. Comprehensive profiling of the STE20 kinase family defines features essential for selective substrate targeting and signaling output. Plos Biology. 17: e2006540. PMID 30897078 DOI: 10.1371/Journal.Pbio.2006540 |
0.591 |
|
| 2018 |
Govindasamy K, Khan R, Snyder M, Lou HJ, Du P, Kudyba HM, Muralidharan V, Turk BE, Bhanot P. falciparum cGMP-dependent protein kinase interacts with a subunit of the parasite proteasome. Infection and Immunity. PMID 30323024 DOI: 10.1128/IAI.00523-18 |
0.401 |
|
| 2018 |
Jeschke GR, Lou HJ, Weise K, Hammond CI, Demonch M, Brennwald P, Turk BE. Substrate priming enhances phosphorylation by the budding yeast kinases Kin1 and Kin2. The Journal of Biological Chemistry. PMID 30305396 DOI: 10.1074/jbc.RA118.005651 |
0.419 |
|
| 2018 |
Turk BE. Exceptionally Selective Substrate Targeting by the Metalloprotease Anthrax Lethal Factor. Advances in Experimental Medicine and Biology. PMID 30267305 DOI: 10.1007/5584_2018_273 |
0.405 |
|
| 2018 |
Barber KW, Miller CJ, Jun JW, Lou HJ, Turk BE, Rinehart J. Kinase Substrate Profiling Using a Proteome-wide Serine-Oriented Human Peptide Library. Biochemistry. PMID 29920078 DOI: 10.1021/Acs.Biochem.8B00410 |
0.439 |
|
| 2018 |
Miller CJ, Turk BE. Homing in: Mechanisms of Substrate Targeting by Protein Kinases. Trends in Biochemical Sciences. PMID 29544874 DOI: 10.1016/j.tibs.2018.02.009 |
0.383 |
|
| 2018 |
Marholz LJ, Zeringo NA, Lou HJ, Turk BE, Parker LL. In Silico Design and in Vitro Characterization of Universal Tyrosine Kinase Peptide Substrates. Biochemistry. PMID 29528224 DOI: 10.1021/Acs.Biochem.8B00044 |
0.369 |
|
| 2018 |
Hara M, Lourido S, Petrova B, Lou HJ, Von Stetina JR, Kashevsky H, Turk BE, Orr-Weaver TL. Identification of PNG kinase substrates uncovers interactions with the translational repressor TRAL in the oocyte-to-embryo transition. Elife. 7. PMID 29480805 DOI: 10.7554/Elife.33150 |
0.365 |
|
| 2018 |
Turk BE. Glycogen synthase kinase-3β regulation: another kinase gets in on the AKT. Febs Letters. PMID 29417553 DOI: 10.1002/1873-3468.12995 |
0.302 |
|
| 2017 |
Advani G, Lim YC, Catimel B, Lio DSS, Ng NLY, Chüeh AC, Tran M, Anasir MI, Verkade H, Zhu HJ, Turk BE, Smithgall TE, Ang CS, Griffin M, Cheng HC. Csk-homologous kinase (Chk) is an efficient inhibitor of Src-family kinases but a poor catalyst of phosphorylation of their C-terminal regulatory tyrosine. Cell Communication and Signaling : Ccs. 15: 29. PMID 28784162 DOI: 10.1186/S12964-017-0186-X |
0.367 |
|
| 2017 |
Miller CJ, Muftuoglu Y, Turk BE. A high throughput assay to identify substrate-selective inhibitors of the ERK protein kinases. Biochemical Pharmacology. PMID 28647489 DOI: 10.1016/j.bcp.2017.06.127 |
0.43 |
|
| 2017 |
Cobbaut M, Derua R, Döppler H, Lou HJ, Vandoninck S, Storz P, Turk BE, Seufferlein T, Waelkens E, Janssens V, Van Lint J. Differential regulation of PKD isoforms in oxidative stress conditions through phosphorylation of a conserved Tyr in the P+1 loop. Scientific Reports. 7: 887. PMID 28428613 DOI: 10.1038/S41598-017-00800-W |
0.375 |
|
| 2017 |
Chen C, Nimlamool W, Miller CJ, Lou HJ, Turk BE. Rational redesign of a functional protein kinase-substrate interaction. Acs Chemical Biology. PMID 28314095 DOI: 10.1021/acschembio.7b00089 |
0.441 |
|
| 2017 |
Tio CW, Omerza G, Phillips T, Lou HJ, Turk BE, Winter E. Ssp2 binding activates the Smk1 MAPK. Molecular and Cellular Biology. PMID 28223369 DOI: 10.1128/Mcb.00607-16 |
0.37 |
|
| 2016 |
Goldberg AB, Cho E, Miller CJ, Lou HJ, Turk BE. Identification of a substrate-selective exosite within the metalloproteinase anthrax lethal factor. The Journal of Biological Chemistry. PMID 27909054 DOI: 10.1074/jbc.M116.761734 |
0.412 |
|
| 2016 |
Hamill S, Lou HJ, Turk BE, Boggon TJ. Structural Basis for Noncanonical Substrate Recognition of Cofilin/ADF Proteins by LIM Kinases. Molecular Cell. 62: 397-408. PMID 27153537 DOI: 10.1016/j.molcel.2016.04.001 |
0.371 |
|
| 2016 |
Goldberg AB, Turk BE. Inhibitors of the Metalloproteinase Anthrax Lethal Factor. Current Topics in Medicinal Chemistry. PMID 27072692 |
0.352 |
|
| 2016 |
Mathea S, Abdul Azeez KR, Salah E, Tallant C, Wolfreys F, Konietzny R, Fischer R, Lou HJ, Brennan PE, Schnapp G, Pautsch A, Kessler BM, Turk BE, Knapp S. Structure of the Human Protein Kinase ZAK in Complex with Vemurafenib. Acs Chemical Biology. PMID 26999302 DOI: 10.1021/Acschembio.6B00043 |
0.426 |
|
| 2016 |
Miller CJ, Turk BE. Rapid Identification of Protein Kinase Phosphorylation Site Motifs Using Combinatorial Peptide Libraries. Methods in Molecular Biology (Clifton, N.J.). 1360: 203-16. PMID 26501912 DOI: 10.1007/978-1-4939-3073-9_15 |
0.42 |
|
| 2016 |
Deng Y, Turk BE. Analysis of Protein Tyrosine Kinase Specificity Using Positional Scanning Peptide Microarrays. Methods in Molecular Biology (Clifton, N.J.). 1352: 27-34. PMID 26490465 DOI: 10.1007/978-1-4939-3037-1_3 |
0.304 |
|
| 2015 |
Agarwal D, Qi Y, Jiang T, Liu X, Shi W, Wali VB, Turk B, Ross JS, Fraser Symmans W, Pusztai L, Hatzis C. Characterization of DNA variants in the human kinome in breast cancer. Scientific Reports. 5: 14736. PMID 26420498 DOI: 10.1038/Srep14736 |
0.341 |
|
| 2015 |
Egan DF, Chun MG, Vamos M, Zou H, Rong J, Miller CJ, Lou HJ, Raveendra-Panickar D, Yang CC, Sheffler DJ, Teriete P, Asara JM, Turk BE, Cosford ND, Shaw RJ. Small Molecule Inhibition of the Autophagy Kinase ULK1 and Identification of ULK1 Substrates. Molecular Cell. PMID 26118643 DOI: 10.1016/J.Molcel.2015.05.031 |
0.422 |
|
| 2015 |
Osman K, Lou HJ, Qiu W, Brand V, Edwards AM, Turk BE, Hui R. Biochemical characterization of FIKK8-a unique protein kinase from the malaria parasite Plasmodium falciparum and other apicomplexans. Molecular and Biochemical Parasitology. PMID 26112892 DOI: 10.1016/j.molbiopara.2015.06.002 |
0.365 |
|
| 2014 |
Howard CJ, Hanson-Smith V, Kennedy KJ, Miller CJ, Lou HJ, Johnson AD, Turk BE, Holt LJ. Ancestral resurrection reveals evolutionary mechanisms of kinase plasticity. Elife. 3. PMID 25310241 DOI: 10.7554/Elife.04126 |
0.397 |
|
| 2014 |
Deng Y, Alicea-Velázquez NL, Bannwarth L, Lehtonen SI, Boggon TJ, Cheng HC, Hytönen VP, Turk BE. Global analysis of human nonreceptor tyrosine kinase specificity using high-density peptide microarrays. Journal of Proteome Research. 13: 4339-46. PMID 25164267 DOI: 10.1021/pr500503q |
0.412 |
|
| 2014 |
Goodwin JM, Svensson RU, Lou HJ, Winslow MM, Turk BE, Shaw RJ. An AMPK-independent signaling pathway downstream of the LKB1 tumor suppressor controls Snail1 and metastatic potential. Molecular Cell. 55: 436-50. PMID 25042806 DOI: 10.1016/J.Molcel.2014.06.021 |
0.369 |
|
| 2014 |
Galan JA, Geraghty KM, Lavoie G, Kanshin E, Tcherkezian J, Calabrese V, Jeschke GR, Turk BE, Ballif BA, Blenis J, Thibault P, Roux PP. Phosphoproteomic analysis identifies the tumor suppressor PDCD4 as a RSK substrate negatively regulated by 14-3-3. Proceedings of the National Academy of Sciences of the United States of America. 111: E2918-27. PMID 25002506 DOI: 10.1073/Pnas.1405601111 |
0.406 |
|
| 2014 |
Maiolica A, de Medina-Redondo M, Schoof EM, Chaikuad A, Villa F, Gatti M, Jeganathan S, Lou HJ, Novy K, Hauri S, Toprak UH, Herzog F, Meraldi P, Penengo L, Turk BE, et al. Modulation of the chromatin phosphoproteome by the Haspin protein kinase. Molecular & Cellular Proteomics : McP. 13: 1724-40. PMID 24732914 DOI: 10.1074/Mcp.M113.034819 |
0.37 |
|
| 2014 |
Papinski D, Schuschnig M, Reiter W, Wilhelm L, Barnes CA, Maiolica A, Hansmann I, Pfaffenwimmer T, Kijanska M, Stoffel I, Lee SS, Brezovich A, Lou JH, Turk BE, Aebersold R, et al. Early steps in autophagy depend on direct phosphorylation of Atg9 by the Atg1 kinase. Molecular Cell. 53: 471-83. PMID 24440502 DOI: 10.1016/J.Molcel.2013.12.011 |
0.332 |
|
| 2014 |
Chen C, Ha BH, Thévenin AF, Lou HJ, Zhang R, Yip KY, Peterson JR, Gerstein M, Kim PM, Filippakopoulos P, Knapp S, Boggon TJ, Turk BE. Identification of a major determinant for serine-threonine kinase phosphoacceptor specificity. Molecular Cell. 53: 140-7. PMID 24374310 DOI: 10.1016/J.Molcel.2013.11.013 |
0.413 |
|
| 2013 |
Gao J, Ha BH, Lou HJ, Morse EM, Zhang R, Calderwood DA, Turk BE, Boggon TJ. Substrate and inhibitor specificity of the type II p21-activated kinase, PAK6. Plos One. 8: e77818. PMID 24204982 DOI: 10.1371/Journal.Pone.0077818 |
0.308 |
|
| 2013 |
Kang SA, Pacold ME, Cervantes CL, Lim D, Lou HJ, Ottina K, Gray NS, Turk BE, Yaffe MB, Sabatini DM. mTORC1 phosphorylation sites encode their sensitivity to starvation and rapamycin. Science (New York, N.Y.). 341: 1236566. PMID 23888043 DOI: 10.1126/Science.1236566 |
0.567 |
|
| 2013 |
Newman RH, Hu J, Rho HS, Xie Z, Woodard C, Neiswinger J, Cooper C, Shirley M, Clark HM, Hu S, Hwang W, Jeong JS, Wu G, Lin J, Gao X, ... ... Turk BE, et al. Construction of human activity-based phosphorylation networks. Molecular Systems Biology. 9: 655. PMID 23549483 DOI: 10.1038/Msb.2013.12 |
0.374 |
|
| 2013 |
Lourido S, Jeschke GR, Turk BE, Sibley LD. Exploiting the unique ATP-binding pocket of toxoplasma calcium-dependent protein kinase 1 to identify its substrates. Acs Chemical Biology. 8: 1155-62. PMID 23530747 DOI: 10.1021/Cb400115Y |
0.373 |
|
| 2012 |
Deng Y, Couch BA, Koleske AJ, Turk BE. A peptide photoaffinity probe specific for the active conformation of the Abl tyrosine kinase. Chembiochem : a European Journal of Chemical Biology. 13: 2510-2. PMID 23081945 DOI: 10.1002/Cbic.201200560 |
0.328 |
|
| 2012 |
Lee YJ, Jeschke GR, Roelants FM, Thorner J, Turk BE. Reciprocal phosphorylation of yeast glycerol-3-phosphate dehydrogenases in adaptation to distinct types of stress. Molecular and Cellular Biology. 32: 4705-17. PMID 22988299 DOI: 10.1128/MCB.00897-12 |
0.355 |
|
| 2012 |
Ha BH, Davis MJ, Chen C, Lou HJ, Gao J, Zhang R, Krauthammer M, Halaban R, Schlessinger J, Turk BE, Boggon TJ. Type II p21-activated kinases (PAKs) are regulated by an autoinhibitory pseudosubstrate. Proceedings of the National Academy of Sciences of the United States of America. 109: 16107-12. PMID 22988085 DOI: 10.1073/Pnas.1214447109 |
0.312 |
|
| 2012 |
Wong A, Zhang YW, Jeschke GR, Turk BE, Rudnick G. Cyclic GMP-dependent stimulation of serotonin transport does not involve direct transporter phosphorylation by cGMP-dependent protein kinase. The Journal of Biological Chemistry. 287: 36051-8. PMID 22942288 DOI: 10.1074/Jbc.M112.394726 |
0.386 |
|
| 2012 |
Bannwarth L, Goldberg AB, Chen C, Turk BE. Identification of exosite-targeting inhibitors of anthrax lethal factor by high-throughput screening. Chemistry & Biology. 19: 875-82. PMID 22840775 DOI: 10.1016/j.chembiol.2012.05.013 |
0.409 |
|
| 2012 |
Shehata SN, Hunter RW, Ohta E, Peggie MW, Lou HJ, Sicheri F, Zeqiraj E, Turk BE, Sakamoto K. Analysis of substrate specificity and cyclin Y binding of PCTAIRE-1 kinase Cellular Signalling. 24: 2085-2094. PMID 22796189 DOI: 10.1016/j.cellsig.2012.06.018 |
0.424 |
|
| 2012 |
Deng Y, Couch BA, Koleske AJ, Turk BE. Inside Cover: A Peptide Photoaffinity Probe Specific for the Active Conformation of the Abl Tyrosine Kinase (ChemBioChem 17/2012) Chembiochem. 13: 2462-2462. DOI: 10.1002/Cbic.201290071 |
0.309 |
|
| 2011 |
Ia KK, Jeschke GR, Deng Y, Kamaruddin MA, Williamson NA, Scanlon DB, Culvenor JG, Hossain MI, Purcell AW, Liu S, Zhu HJ, Catimel B, Turk BE, Cheng HC. Defining the substrate specificity determinants recognized by the active site of C-terminal Src kinase-homologous kinase (CHK) and identification of β-synuclein as a potential CHK physiological substrate. Biochemistry. 50: 6667-77. PMID 21699177 DOI: 10.1021/bi2001938 |
0.43 |
|
| 2010 |
Sirichandra C, Davanture M, Turk BE, Zivy M, Valot B, Leung J, Merlot S. The Arabidopsis ABA-activated kinase OST1 phosphorylates the bZIP transcription factor ABF3 and creates a 14-3-3 binding site involved in its turnover. Plos One. 5: e13935. PMID 21085673 DOI: 10.1371/journal.pone.0013935 |
0.333 |
|
| 2010 |
Kikani CK, Antonysamy SA, Bonanno JB, Romero R, Zhang FF, Russell M, Gheyi T, Iizuka M, Emtage S, Sauder JM, Turk BE, Burley SK, Rutter J. Structural bases of PAS domain-regulated kinase (PASK) activation in the absence of activation loop phosphorylation. The Journal of Biological Chemistry. 285: 41034-43. PMID 20943661 DOI: 10.1074/Jbc.M110.157594 |
0.396 |
|
| 2010 |
Chen C, Turk BE. Analysis of serine-threonine kinase specificity using arrayed positional scanning peptide libraries. Current Protocols in Molecular Biology. Unit 18.14. PMID 20583094 DOI: 10.1002/0471142727.mb1814s91 |
0.365 |
|
| 2010 |
Leissring MA, Malito E, Hedouin S, Reinstatler L, Sahara T, Abdul-Hay SO, Choudhry S, Maharvi GM, Fauq AH, Huzarska M, May PS, Choi S, Logan TP, Turk BE, Cantley LC, et al. Designed inhibitors of insulin-degrading enzyme regulate the catabolism and activity of insulin. Plos One. 5: e10504. PMID 20498699 DOI: 10.1371/Journal.Pone.0010504 |
0.429 |
|
| 2010 |
Mok J, Kim PM, Lam HY, Piccirillo S, Zhou X, Jeschke GR, Sheridan DL, Parker SA, Desai V, Jwa M, Cameroni E, Niu H, Good M, Remenyi A, Ma JL, ... ... Turk BE, et al. Deciphering protein kinase specificity through large-scale analysis of yeast phosphorylation site motifs. Science Signaling. 3: ra12. PMID 20159853 DOI: 10.1126/Scisignal.2000482 |
0.426 |
|
| 2010 |
NIWAYAMA S, LOH C, TURK BE, LIU JO, MIYACHI H, HASHIMOTO Y. ChemInform Abstract: Enhanced Potency of Perfluorinated Thalidomide Derivatives for Inhibition of LPS-Induced Tumor Necrosis Factor-α Production is Associated with a Change of Mechanism of Action. Cheminform. 29: no-no. DOI: 10.1002/CHIN.199836166 |
0.71 |
|
| 2009 |
Caescu CI, Jeschke GR, Turk BE. Active-site determinants of substrate recognition by the metalloproteinases TACE and ADAM10. The Biochemical Journal. 424: 79-88. PMID 19715556 DOI: 10.1042/BJ20090549 |
0.323 |
|
| 2009 |
Davis TL, Walker JR, Allali-Hassani A, Parker SA, Turk BE, Dhe-Paganon S. Structural recognition of an optimized substrate for the ephrin family of receptor tyrosine kinases. The Febs Journal. 276: 4395-404. PMID 19678838 DOI: 10.1111/j.1742-4658.2009.07147.x |
0.351 |
|
| 2009 |
Bullock AN, Das S, Debreczeni JE, Rellos P, Fedorov O, Niesen FH, Guo K, Papagrigoriou E, Amos AL, Cho S, Turk BE, Ghosh G, Knapp S. Kinase domain insertions define distinct roles of CLK kinases in SR protein phosphorylation. Structure (London, England : 1993). 17: 352-62. PMID 19278650 DOI: 10.1016/J.Str.2008.12.023 |
0.435 |
|
| 2009 |
Huang X, Finerty P, Walker JR, Butler-Cole C, Vedadi M, Schapira M, Parker SA, Turk BE, Thompson DA, Dhe-Paganon S. Structural insights into the inhibited states of the Mer receptor tyrosine kinase. Journal of Structural Biology. 165: 88-96. PMID 19028587 DOI: 10.1016/j.jsb.2008.10.003 |
0.321 |
|
| 2008 |
Filippakopoulos P, Kofler M, Hantschel O, Gish GD, Grebien F, Salah E, Neudecker P, Kay LE, Turk BE, Superti-Furga G, Pawson T, Knapp S. Structural coupling of SH2-kinase domains links Fes and Abl substrate recognition and kinase activation. Cell. 134: 793-803. PMID 18775312 DOI: 10.1016/J.Cell.2008.07.047 |
0.346 |
|
| 2008 |
Miller ML, Jensen LJ, Diella F, Jørgensen C, Tinti M, Li L, Hsiung M, Parker SA, Bordeaux J, Sicheritz-Ponten T, Olhovsky M, Pasculescu A, Alexander J, Knapp S, Blom N, ... ... Turk BE, et al. Linear motif atlas for phosphorylation-dependent signaling. Science Signaling. 1: ra2. PMID 18765831 DOI: 10.1126/Scisignal.1159433 |
0.586 |
|
| 2008 |
Sheridan DL, Kong Y, Parker SA, Dalby KN, Turk BE. Substrate discrimination among mitogen-activated protein kinases through distinct docking sequence motifs. The Journal of Biological Chemistry. 283: 19511-20. PMID 18482985 DOI: 10.1074/Jbc.M801074200 |
0.453 |
|
| 2008 |
Gwinn DM, Shackelford DB, Egan DF, Mihaylova MM, Mery A, Vasquez DS, Turk BE, Shaw RJ. AMPK phosphorylation of raptor mediates a metabolic checkpoint. Molecular Cell. 30: 214-26. PMID 18439900 DOI: 10.1016/J.Molcel.2008.03.003 |
0.316 |
|
| 2008 |
Vlad F, Turk BE, Peynot P, Leung J, Merlot S. A versatile strategy to define the phosphorylation preferences of plant protein kinases and screen for putative substrates. The Plant Journal : For Cell and Molecular Biology. 55: 104-17. PMID 18363786 DOI: 10.1111/j.1365-313X.2008.03488.x |
0.417 |
|
| 2008 |
Turk BE. Understanding and exploiting substrate recognition by protein kinases. Current Opinion in Chemical Biology. 12: 4-10. PMID 18282484 DOI: 10.1016/j.cbpa.2008.01.018 |
0.408 |
|
| 2008 |
Pike AC, Rellos P, Niesen FH, Turnbull A, Oliver AW, Parker SA, Turk BE, Pearl LH, Knapp S. Activation segment dimerization: a mechanism for kinase autophosphorylation of non-consensus sites. The Embo Journal. 27: 704-14. PMID 18239682 DOI: 10.1038/emboj.2008.8 |
0.382 |
|
| 2008 |
Eswaran J, Bernad A, Ligos JM, Guinea B, Debreczeni JE, Sobott F, Parker SA, Najmanovich R, Turk BE, Knapp S. Structure of the human protein kinase MPSK1 reveals an atypical activation loop architecture. Structure (London, England : 1993). 16: 115-24. PMID 18184589 DOI: 10.1016/J.Str.2007.10.026 |
0.38 |
|
| 2007 |
Bunkoczi G, Salah E, Filippakopoulos P, Fedorov O, Müller S, Sobott F, Parker SA, Zhang H, Min W, Turk BE, Knapp S. Structural and functional characterization of the human protein kinase ASK1. Structure (London, England : 1993). 15: 1215-26. PMID 17937911 DOI: 10.1016/j.str.2007.08.011 |
0.396 |
|
| 2007 |
Hutti JE, Turk BE, Asara JM, Ma A, Cantley LC, Abbott DW. IκB kinase β phosphorylates the K63 deubiquitinase A20 to cause feedback inhibition of the NF-κB pathway Molecular and Cellular Biology. 27: 7451-7461. PMID 17709380 DOI: 10.1128/Mcb.01101-07 |
0.477 |
|
| 2007 |
Rennefahrt UE, Deacon SW, Parker SA, Devarajan K, Beeser A, Chernoff J, Knapp S, Turk BE, Peterson JR. Specificity profiling of Pak kinases allows identification of novel phosphorylation sites. The Journal of Biological Chemistry. 282: 15667-78. PMID 17392278 DOI: 10.1074/Jbc.M700253200 |
0.41 |
|
| 2006 |
Turk BE, Hutti JE, Cantley LC. Determining protein kinase substrate specificity by parallel solution-phase assay of large numbers of peptide substrates Nature Protocols. 1: 375-379. PMID 17406259 DOI: 10.1038/Nprot.2006.57 |
0.54 |
|
| 2006 |
Fu Z, Larson KA, Chitta RK, Parker SA, Turk BE, Lawrence MW, Kaldis P, Galaktionov K, Cohn SM, Shabanowitz J, Hunt DF, Sturgill TW. Identification of yin-yang regulators and a phosphorylation consensus for male germ cell-associated kinase (MAK)-related kinase. Molecular and Cellular Biology. 26: 8639-54. PMID 16954377 DOI: 10.1128/Mcb.00816-06 |
0.391 |
|
| 2006 |
Turk BE, Lee DH, Yamakoshi Y, Klingenhoff A, Reichenberger E, Wright JT, Simmer JP, Komisarof JA, Cantley LC, Bartlett JD. MMP-20 is predominately a tooth-specific enzyme with a deep catalytic pocket that hydrolyzes type V collagen Biochemistry. 45: 3863-3874. PMID 16548514 DOI: 10.1021/Bi052252O |
0.379 |
|
| 2005 |
Bullock AN, Debreczeni J, Amos AL, Knapp S, Turk BE. Structure and substrate specificity of the Pim-1 kinase. The Journal of Biological Chemistry. 280: 41675-82. PMID 16227208 DOI: 10.1074/jbc.M510711200 |
0.447 |
|
| 2004 |
Turk BE, Cantley LC. Peptide libraries: at the crossroads of proteomics and bioinformatics. Drug Discovery Today. 9: S47-52. PMID 23573644 |
0.465 |
|
| 2004 |
Hutti JE, Jarrell ET, Chang JD, Abbott DW, Storz P, Toker A, Cantley LC, Turk BE. A rapid method for determining protein kinase phosphorylation specificity. Nature Methods. 1: 27-9. PMID 15782149 DOI: 10.1038/Nmeth708 |
0.694 |
|
| 2004 |
Williamson AL, Lecchi P, Turk BE, Choe Y, Hotez PJ, McKerrow JH, Cantley LC, Sajid M, Craik CS, Loukas A. A multi-enzyme cascade of hemoglobin proteolysis in the intestine of blood-feeding hookworms. The Journal of Biological Chemistry. 279: 35950-7. PMID 15199048 DOI: 10.1074/Jbc.M405842200 |
0.391 |
|
| 2004 |
Turk BE, Cantley LC. Using peptide libraries to identify optimal cleavage motifs for proteolytic enzymes. Methods (San Diego, Calif.). 32: 398-405. PMID 15003602 DOI: 10.1016/J.Ymeth.2003.10.003 |
0.462 |
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| 2004 |
Panchal RG, Hermone AR, Nguyen TL, Wong TY, Schwarzenbacher R, Schmidt J, Lane D, McGrath C, Turk BE, Burnett J, Aman MJ, Little S, Sausville EA, Zaharevitz DW, Cantley LC, et al. Identification of small molecule inhibitors of anthrax lethal factor Nature Structural and Molecular Biology. 11: 67-72. PMID 14718925 DOI: 10.1038/Nsmb711 |
0.504 |
|
| 2004 |
Turk BE, Wong TY, Schwarzenbacher R, Jarrell ET, Leppla SH, Collier RJ, Liddington RC, Cantley LC. The structural basis for substrate and inhibitor selectivity of the anthrax lethal factor. Nature Structural & Molecular Biology. 11: 60-6. PMID 14718924 DOI: 10.1038/Nsmb708 |
0.456 |
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| 2003 |
Martins LM, Turk BE, Cowling V, Borg A, Jarrell ET, Cantley LC, Downward J. Binding specificity and regulation of the serine protease and PDZ domains of HtrA2/Omi. The Journal of Biological Chemistry. 278: 49417-27. PMID 14512424 DOI: 10.1074/Jbc.M308659200 |
0.484 |
|
| 2003 |
Turk BE, Cantley LC. Peptide libraries: at the crossroads of proteomics and bioinformatics. Current Opinion in Chemical Biology. 7: 84-90. PMID 12547431 DOI: 10.1016/S1367-5931(02)00004-2 |
0.465 |
|
| 2002 |
Park HI, Turk BE, Gerkema FE, Cantley LC, Sang QX. Peptide substrate specificities and protein cleavage sites of human endometase/matrilysin-2/matrix metalloproteinase-26. The Journal of Biological Chemistry. 277: 35168-75. PMID 12119297 DOI: 10.1074/Jbc.M205071200 |
0.425 |
|
| 2001 |
Turk BE, Huang LL, Piro ET, Cantley LC. Determination of protease cleavage site motifs using mixture-based oriented peptide libraries Nature Biotechnology. 19: 661-667. PMID 11433279 DOI: 10.1038/90273 |
0.49 |
|
| 2001 |
Bertenshaw GP, Turk BE, Hubbard SJ, Matters GL, Bylander JE, Crisman JM, Cantley LC, Bond JS. Marked Differences between Metalloproteases Meprin A and B in Substrate and Peptide Bond Specificity Journal of Biological Chemistry. 276: 13248-13255. PMID 11278902 DOI: 10.1074/Jbc.M011414200 |
0.408 |
|
| 1999 |
Turk BE, Griffith EC, Wolf S, Biemann K, Chang YH, Liu JO. Selective inhibition of amino-terminal methionine processing by TNP-470 and ovalicin in endothelial cells. Chemistry & Biology. 6: 823-33. PMID 10574784 DOI: 10.1016/S1074-5521(99)80129-X |
0.317 |
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| 1998 |
Niwayama S, Loh C, Turk BE, Liu JO, Miyachi H, Hashimoto Y. Enhanced potency of perfluorinated thalidomide derivatives for inhibition of LPS-induced tumor necrosis factor-α production is associated with a change of mechanism of action Bioorganic and Medicinal Chemistry Letters. 8: 1071-1076. PMID 9871710 DOI: 10.1016/S0960-894X(98)00171-1 |
0.727 |
|
| 1998 |
Turk BE, Su Z, Liu JO. Synthetic analogues of TNP-470 and ovalicin reveal a common molecular basis for inhibition of angiogenesis and immunosuppression Bioorganic and Medicinal Chemistry. 6: 1163-1169. PMID 9784858 DOI: 10.1016/S0968-0896(98)00078-9 |
0.705 |
|
| 1997 |
Griffith EC, Su Z, Turk BE, Chen S, Chang YH, Wu Z, Biemann K, Liu JO. Methionine aminopeptidase (type 2) is the common target for angiogenesis inhibitors AGM-1470 and ovalicin. Chemistry & Biology. 4: 461-71. PMID 9224570 DOI: 10.1016/S1074-5521(97)90198-8 |
0.723 |
|
| 1996 |
Niwayama S, Turk BE, Liu JO. Potent inhibition of tumor necrosis factor-α production by tetrafluorothalidomide and tetrafluorophthalimides Journal of Medicinal Chemistry. 39: 3044-3045. PMID 8759624 DOI: 10.1021/Jm960284R |
0.611 |
|
| 1996 |
Turk BE, Jiang H, Liu JO. Binding of thalidomide to α1-acid glycoprotein may be involved in its inhibition of tumor necrosis factor α production Proceedings of the National Academy of Sciences of the United States of America. 93: 7552-7556. PMID 8755512 DOI: 10.1073/Pnas.93.15.7552 |
0.392 |
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