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Raymond L. Funk, Ph.D. - Publications

Affiliations: 
Chemistry Pennsylvania State University, State College, PA, United States 
Area:
Natural products synthesis
Website:
http://www.chem.psu.edu/directory/rlf8

75 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2012 Belmar J, Funk RL. Total synthesis of (±)-communesin F via a cycloaddition with indol-2-one. Journal of the American Chemical Society. 134: 16941-3. PMID 22978807 DOI: 10.1021/Ja307277W  0.703
2012 Funk RL, Belmar J. Total synthesis of (±)-isophellibiline. Tetrahedron Letters. 53: 176-178. PMID 22308006 DOI: 10.1016/J.Tetlet.2011.10.161  0.77
2011 Huntley RJ, Funk RL. Total synthesis of (±)-γ-lycorane via the electrocyclic ring closure of a divinylpyrroline. Tetrahedron Letters. 52: 6671-6674. PMID 22081730 DOI: 10.1016/J.Tetlet.2011.09.138  0.801
2011 Nilson MG, Funk RL. Total synthesis of (±)-cortistatin J from furan. Journal of the American Chemical Society. 133: 12451-3. PMID 21761900 DOI: 10.1021/Ja206138D  0.828
2010 Nilson MG, Funk RL. Total synthesis of (-)-nakadomarin A. Organic Letters. 12: 4912-5. PMID 20932022 DOI: 10.1021/Ol102079Z  0.826
2010 Maeng J, Funk RL. ChemInform Abstract: Total Synthesis of (.+-.)-Fasicularin via a 2-Amidoacrolein Cycloaddition. Cheminform. 33: no-no. DOI: 10.1002/chin.200225199  0.483
2010 Greshock TJ, Funk RL. ChemInform Abstract: Total Synthesis of (.+-.)-Lepadiformine via an Amidoacrolein Cycloaddition. Cheminform. 33: no-no. DOI: 10.1002/chin.200209218  0.766
2010 Aungst Jr. RA, Funk RL. ChemInform Abstract: Synthesis of (Z)-2-Acyl-2-enals via Retrocycloadditions of 5-Acyl-4-alkyl-4H-1,3-dioxins: Application in the Total Synthesis of the Cytotoxin (.+-.)-Euplotin A (X). Cheminform. 33: no-no. DOI: 10.1002/chin.200204245  0.389
2006 Huntley RJ, Funk RL. A strategy for the total synthesis of dragmacidin E. Construction of the core ring system. Organic Letters. 8: 4775-8. PMID 17020300 DOI: 10.1021/Ol0617547  0.812
2006 Crawley SL, Funk RL. Generation of aza-ortho-xylylenes via ring opening of 2-(2-acylaminophenyl)aziridines: application in the construction of the communesin ring system. Organic Letters. 8: 3995-8. PMID 16928057 DOI: 10.1021/Ol061461D  0.816
2006 Nilson MG, Funk RL. Generation of N-acyliminium ions via intramolecular conjugate addition reactions: a strategy for the total synthesis of nakadomarin A. Organic Letters. 8: 3833-6. PMID 16898829 DOI: 10.1021/Ol061463Y  0.808
2006 He Y, Funk RL. Total syntheses of (+/-)-beta-erythroidine and (+/-)-8-oxo-beta-erythroidine by an intramolecular Diels-Alder cycloaddition of a 2-amidoacrolein. Organic Letters. 8: 3689-92. PMID 16898793 DOI: 10.1021/Ol061267R  0.461
2006 Huntley RJ, Funk RL. Total syntheses of (+/-)-cis-trikentrin A and (+/-)-cis-trikentrin B via electrocyclic ring closures of 2,3-divinylpyrrolines. Organic Letters. 8: 3403-6. PMID 16836416 DOI: 10.1021/Ol061259A  0.807
2006 Greshock TJ, Funk RL. An approach to the total synthesis of welwistatin. Organic Letters. 8: 2643-5. PMID 16737334 DOI: 10.1021/Ol0608799  0.802
2006 Greshock TJ, Funk RL. Synthesis of indoles via 6pi-electrocyclic ring closures of trienecarbamates. Journal of the American Chemical Society. 128: 4946-7. PMID 16608316 DOI: 10.1021/Ja060282O  0.757
2006 Greshock TJ, Funk RL. 6-(2-Haloethyl)-2,2-dimethyl-4H-1,3-dioxins: versatile haloethyl vinyl ketone equivalents for carbocycle construction Tetrahedron Letters. 47: 5437-5439. DOI: 10.1016/J.Tetlet.2006.05.171  0.762
2005 Fuchs JR, Funk RL. Indol-2-one intermediates: mechanistic evidence and synthetic utility. Total syntheses of (+/-)-flustramines A and C. Organic Letters. 7: 677-80. PMID 15704923 DOI: 10.1021/Ol047532V  0.65
2004 Cossey KN, Funk RL. Diastereoselective synthesis of 2,3,6-trisubstituted tetrahydropyran-4-ones via Prins cyclizations of enecarbamates: a formal synthesis of (+)-ratjadone A. Journal of the American Chemical Society. 126: 12216-7. PMID 15453725 DOI: 10.1021/Ja046940R  0.527
2004 Fuchs JR, Funk RL. Total synthesis of (+/-)-perophoramidine. Journal of the American Chemical Society. 126: 5068-9. PMID 15099080 DOI: 10.1021/Ja049569G  0.702
2003 Crawley SL, Funk RL. A synthetic approach to nomofungin/communesin B. Organic Letters. 5: 3169-71. PMID 12943379 DOI: 10.1021/Ol034407V  0.809
2002 Maeng JH, Funk RL. Total synthesis of (+/-)fasicularin via a 2-amidoacrolein cycloaddition. Organic Letters. 4: 331-3. PMID 11820872 DOI: 10.1021/Ol016850G  0.655
2002 Greshock TJ, Funk RL. 6-Bromomethyl-4H-1,3-dioxin: a versatile bromomethyl vinyl ketone equivalent for heterocycle and carbocycle construction. Journal of the American Chemical Society. 124: 754-5. PMID 11817942 DOI: 10.1021/Ja0123554  0.775
2002 Aungst RA, Funk RL, Harmata M. Stereoselective preparation of (Z)-2-(trialkylsilyloxy)-2-alkenals by retrocycloaddition reactions of 4h-4-alkyl-5-(trialkylsilyloxy)-1,3-dioxins. Useful reactants for Lewis acid-catalyzed [4 + 3] cyclizations Chemtracts. 15: 189-194. DOI: 10.1002/chin.200302273  0.404
2001 Fuchs JR, Funk RL. Total synthesis of (+/-)-lennoxamine and (+/-)-aphanorphine by intramolecular electrophilic aromatic substitution reactions of 2-amidoacroleins. Organic Letters. 3: 3923-5. PMID 11720570 DOI: 10.1021/Ol016795B  0.773
2001 Aungst RA, Funk RL. Stereoselective preparation of (Z)-2-(trialkylsilyloxy)-2-alkenals by retrocycloaddition reactions of 4H-4-Alkyl-5-(trialkylsilyloxy)-1,3-dioxins. Useful reactants for Lewis acid catalyzed [4 + 3] cyclizations. Organic Letters. 3: 3553-5. PMID 11678706 DOI: 10.1021/Ol016668F  0.52
2001 Greshock TJ, Funk RL. Total synthesis of (+/-)-lepadiformine via an amidoacrolein cycloaddition. Organic Letters. 3: 3511-4. PMID 11678695 DOI: 10.1021/Ol0165903  0.832
2001 Fuchs JR, Funk RL. Intramolecular electrophilic aromatic substitution reactions of 2-amidoacroleins: a new method for the preparation of tetrahydroisoquinolines, tetrahydro-3-benzazepines, and hexahydro-3-benzazocines. Organic Letters. 3: 3349-51. PMID 11594831 DOI: 10.1021/Ol016592N  0.753
2001 Aungst RA, Funk RL. Synthesis of (Z)-2-acyl-2-enals via retrocycloadditions of 5-acyl-4-alkyl-4H-1,3-dioxins: application in the total synthesis of the cytotoxin (+/-)-euplotin A. Journal of the American Chemical Society. 123: 9455-6. PMID 11562234 DOI: 10.1021/Ja011470B  0.515
2001 Aungst RA, Chan C, Funk RL. Total synthesis of the sesquiterpene (+/-)-illudin C via an intramolecular nitrile oxide cycloaddition. Organic Letters. 3: 2611-3. PMID 11483073 DOI: 10.1021/Ol016314O  0.577
2001 Maeng JH, Funk RL. Total synthesis of the immunosuppressant FR901483 via an amidoacrolein cycloaddition. Organic Letters. 3: 1125-8. PMID 11348175 DOI: 10.1021/Ol015506G  0.641
2001 Greshock TJ, Funk RL. Total synthesis of (±)-lepadiformine via an amidoacrolein cycloaddition Organic Letters. 3: 3511-3514. DOI: 10.1021/ol0165903  0.699
2000 Fearnley SP, Funk RL, Gregg RJ. Preparation of 2-alkyl- and 2-acylpropenals from 5-(trifluoromethanesulfonyloxy)-4H-1,3-dioxin: A versatile acrolein α-cation synthon Tetrahedron. 56: 10275-10281. DOI: 10.1016/S0040-4020(00)00872-3  0.462
1999 Funk RL, Yang G. C(1)-substituted menthol derivatives: Self-removing chiral auxiliaries for asymmetric conjugate additions to cycloalkenones Tetrahedron Letters. 40: 1073-1074. DOI: 10.1016/S0040-4039(98)02627-6  0.488
1998 Young ERR, Funk RL. A practical synthesis of pyrene-4,5-dione Journal of Organic Chemistry. 63: 9995-9996. DOI: 10.1021/Jo970344G  0.428
1996 Funk RL, Yost KJ. Preparation and Diels-Alder Cycloaddition of 2-Acyloxyacroleins. Facile Synthesis of Functionalized Taxol A-Ring Synthons. The Journal of Organic Chemistry. 61: 2598-2599. PMID 11667085 DOI: 10.1021/Jo960340W  0.614
1996 Funk RL, Young ERR, Williams RM, Flanagan MF, Cecil TL. Photochemical cycloaromatization reactions of ortho-dialkynylarenes: A new class of DNA photocleaving agents Journal of the American Chemical Society. 118: 3291-3292. DOI: 10.1021/Ja9521482  0.327
1993 Funk RL, Olmstead TA, Parvez M, Stallman JB. Stereoselective construction of the complete ingenane ring system Journal of Organic Chemistry. 58: 5873-5875. DOI: 10.1021/Jo00074A003  0.485
1993 Funk RL, Fitzgerald JF, Olmstead TA, Para KS, Wos JA. Titanium-mediated cyclizations of .beta.-keto esters with acetals: a convenient route to 2-carbalkoxycycloalkenones Journal of the American Chemical Society. 115: 8849-8850. DOI: 10.1021/Ja00072A052  0.343
1993 Funk RL, Stallman JB, Wos JA. Claisen rearrangements of enol phosphates Journal of the American Chemical Society. 115: 8847-8848. DOI: 10.1021/Ja00072A051  0.351
1993 Funk RL, Bolton GL, Brummond KM, Ellestad KE, Stallman JB. Facile intramolecular carbolithiation reactions of alkylthio- and alkoxyacetylenes by stabilized carbanions. A novel strategy for the synthesis of functionalized carbocycles Journal of the American Chemical Society. 115: 7029-7030. DOI: 10.1021/Ja00068A090  0.726
1993 Funk RL, Umstead-Daggett J, Brummond KM. Stereoselective preparation of vinyl sulfones by protodesilylation of allyl silanes Tetrahedron Letters. 34: 2867-2870. DOI: 10.1016/S0040-4039(00)60467-7  0.726
1989 Funk R, Abelman M, Jellison K. Generation of Ketenes From Carboxylic Acids Using the Mukaiyama Reagent (1-Methyl-2-chloropyridinium Iodide) Synlett. 1989: 36-37. DOI: 10.1055/S-1989-34706  0.318
1988 Funk RL, Olmstead TA, Parvez M. A solution to the in,out-bicyclo[4.4.1]undecan-7-one problem inherent in ingenane total synthesis Journal of the American Chemical Society. 110: 3298-3300. DOI: 10.1021/Ja00218A049  0.326
1988 Funk RL, Novak PM, Abelman MM. Preparation of bridged bicycloalkanes via intramolecular [2+2] cycloadditions of ketenes a short total synthesis of (±)-clovene. Tetrahedron Letters. 29: 1493-1496. DOI: 10.1016/S0040-4039(00)80333-0  0.38
1988 FUNK RL, NOVAK PM, ABELMAN MM. ChemInform Abstract: Preparation of Bridged Bicycloalkanes via Intramolecular (2 + 2)Cycloadditions of Ketenes: A Short Total Synthesis of (.+-.)-Clovene. Cheminform. 19. DOI: 10.1002/chin.198834123  0.477
1987 Funk RL, Daggett JU. Intermolecular cycloaddition reactions of exocyclic nitrones facile synthesis of 1-azaspirocycles Heterocycles. 26: 2175-2182. DOI: 10.3987/R-1987-08-2175  0.376
1987 Funk RL, Bolton GL. A new approach to the cedrane ring system via intramolecular [4 + 2] tropone-olefin cycloaddition. Total synthesis of (.+-.)-.alpha.- and .beta.-pipitzol The Journal of Organic Chemistry. 52: 3173-3174. DOI: 10.1021/Jo00390A042  0.453
1987 FUNK RL, BOLTON GL. ChemInform Abstract: A New Approach to the Cedrane Ring System via Intramolecular (4 + 2) Tropone-Olefin Cycloaddition. Total Synthesis of (.+-.)-α- and (.+-.)-β-Pipitzol (I). Cheminform. 18. DOI: 10.1002/chin.198752365  0.362
1987 Funk RL, Bolton GL. A new approach to the cedrane ring system via intramolecular [4 + 2] tropone-olefin cycloaddition. Total synthesis of (±)-α- and (±)-β-pipitzol Journal of Organic Chemistry. 52: 3173-3174.  0.318
1986 Funk RL, Abelman MM. Synthesis of bridged bicycloalkanes via the alicyclic claisen rearrangement. A new approach to quadrone Journal of Organic Chemistry. 51: 3247-3248. DOI: 10.1021/Jo00366A046  0.448
1986 Funk RL, Bolton GL. Intramolecular [6 + 4] and [4 + 2] tropone-olefin cycloaddition reactions. Facile synthesis of the ingenane ring system Journal of the American Chemical Society. 108: 4655-4657. DOI: 10.1021/Ja00275A069  0.659
1986 Funk RL, Abelman MM, Munger JD. Claisen-rearrangement-mediated ring contraction of macrocyclic lactones. A new approach to carbocycles and heterocycles Tetrahedron. 42: 2831-2846. DOI: 10.1016/S0040-4020(01)90572-1  0.397
1986 FUNK RL, BOLTON GL. ChemInform Abstract: Intramolecular [6 + 4] and [4 + 2] Tropone-Olefin Cycloaddition Reactions. Chemischer Informationsdienst. 17. DOI: 10.1002/chin.198648161  0.414
1985 Funk RL, Bolton GL, Daggett JU, Hansen MM, Horcher LHM. Intramolecular cycloaddition reactions of exocyclic nitrones. Application in the total synthesis of terpenes Tetrahedron. 41: 3479-3495. DOI: 10.1016/S0040-4020(01)96702-X  0.487
1985 Funk RL, Munger JDJ. A New Approach To Heterocycles: Synthesis Of (.+-.)-N-Benzoylmeroquinene Methyl Ester Cheminform. 16. DOI: 10.1002/Chin.198519222  0.426
1985 Funk RL, Munger JD. The stereospecific total synthesis of (±)-cis-chrysanthemic acid via the alicyclic claisen rearrangement Journal of Organic Chemistry. 50: 707-709.  0.308
1984 Funk RL, Munger JD. A new approach to heterocycles: synthesis of (.+-.)-N-benzoylmeroquinene methyl ester Journal of Organic Chemistry. 49: 4319-4320. DOI: 10.1021/Jo00196A048  0.426
1984 Funk RL, Mossman CJ, Zeller WE. Hypocholesterolemic agent compactin. an alternative diels-alder strategy for the synthesis of the hexahydronaphthalene portion Tetrahedron Letters. 25: 1655-1658. DOI: 10.1016/S0040-4039(01)81136-9  0.345
1984 Funk RL, Bolton GL. The nitrone route to linearly fused tricyclopentanoids. Another synthesis of hirsutene Journal of Organic Chemistry. 49: 5021-5022. DOI: 10.1002/Chin.198519160  0.541
1984 Funk RL, Munger JD. A new approach to heterocycles: Synthesis of (±)-N-benzoylmeroquinene methyl ester Journal of Organic Chemistry. 49: 4319-4320.  0.319
1983 Funk RL, Horcher LHM, Daggett JU, Hansen MM. Facile bridged bicycloalkane synthesis via intramolecular nitrone-olefin cycloaddition Journal of Organic Chemistry. 48: 2632-2634. DOI: 10.1021/Jo00163A052  0.603
1982 Funk RL, Zeller WE. Hypocholesterolemic agent compactin (ML-236B). Total synthesis of the hexahydronaphthalene portion Journal of Organic Chemistry. 47: 180-182. DOI: 10.1021/Jo00340A050  0.38
1982 Abelman MM, Funk RL, Munger JD. Alicyclic claisen rearrangement. A general carbocycle synthesis based on four-atom-ring contractions of lactones Journal of the American Chemical Society. 104: 4030-4032. DOI: 10.1021/Ja00378A054  0.491
1980 Danishefsky S, Funk RL, Kerwin JF. Claisen rearrangements of lactonic (silyl) enolates: a new route to functionalized cycloalkenes Journal of the American Chemical Society. 102: 6889-6891. DOI: 10.1021/Ja00542A058  0.536
1980 Funk RL, Vollhardt KPC. Transition-metal-catalyzed alkyne cyclizations. A cobalt-mediated total synthesis of dl-estrone Journal of the American Chemical Society. 102: 5253-5261. DOI: 10.1021/Ja00536A023  0.411
1980 Funk RL, Vollhardt KPC. Cooligomerizations of 3-substituted 1,5-hexadiynes with bis(trimethylsilyl)acetylene catalyzed by cobalt. A general synthesis of tricyclic ring systems from acyclic precursors Journal of the American Chemical Society. 102: 5245-5253. DOI: 10.1021/Ja00536A022  0.586
1980 FUNK RL, VOLLHARDT KPC. ChemInform Abstract: TRANSITION-METAL-CATALYZED ALKYNE CYCLIZATIONS. A COBALT-MEDIATED TOTAL SYNTHESIS OF DL-ESTRONE Chemischer Informationsdienst. 11. DOI: 10.1002/chin.198044294  0.313
1977 Funk RL, Vollhardt KP. A cobalt-catalyzed steroid synthesis. Journal of the American Chemical Society. 99: 5483-4. PMID 886107 DOI: 10.1021/Ja00458A044  0.562
1977 FUNK RL, VOLLHARDT KPC. ChemInform Abstract: A COBALT-CATALYZED STEROID SYNTHESIS Chemischer Informationsdienst. 8: no-no. DOI: 10.1002/chin.197745335  0.474
1977 FUNK RL, VOLLHARDT KPC. ChemInform Abstract: HEXA-1,5-DIYN-3-OL ETHERS AS TETRAMETHYNYL SYNTHONS IN COBALT-CATALYZED ACETYLENE COOLIGOMERIZATIONS, A ONE-STEP SYNTHESIS OF 2,3,6,7-TETRAKISTRIMETHYLSILYLNAPHTHALENE Chemischer Informationsdienst. 8: no-no. DOI: 10.1002/chin.197707243  0.522
1977 FUNK RL, VOLLHARDT KPC. ChemInform Abstract: IN SITU GENERATION AND INTRAMOLECULAR TRAPPING OF O-XYLYLENES BY COBALT-CATALYZED ACETYLENE COOLIGOMERIZATIONS. A ONE-STEP SYNTHESIS OF POLYCYCLES Chemischer Informationsdienst. 8: no-no. DOI: 10.1002/chin.197701098  0.371
1976 Funk RL, Vollhardt KPC. Hexa-1,5-diyn-3-ol ethers as tetramethynyl synthons in cobalt-catalysed acetylene co-oligomerisations; a one-step synthesis of 2,3,6,7- tetrakistrimethylsilylnaphthalene Journal of the Chemical Society, Chemical Communications. 833-834. DOI: 10.1039/C39760000833  0.593
1976 Funk RL, Peter K, Vollhardt C. In situ generation and intramolecular trapping of o-xylylenes by cobalt-catalyzed acetylene cooligomerizations. A one-step synthesis of polycycles [43] Journal of the American Chemical Society. 98: 6755-6757. DOI: 10.1021/Ja00437A086  0.464
1975 Aalbersberg WGL, Barkovich AJ, Funk RL, Hillard RL, Vollhardt KPC. Transition metal catalyzed acetylene cyclizations. 4,5-Bis(trimethylsilyl)benzocyclobutene, a highly strained, versatile synthetic intermediate [14] Journal of the American Chemical Society. 97: 5600-5602. DOI: 10.1021/Ja00852A057  0.341
1975 AALBERSBERG WGL, BARKOVICH AJ, FUNK RL, HILLARD RLI, VOLLHARDT KPC. ChemInform Abstract: TRANSITION METAL CATALYZED ACETYLEN CYCLIZATIONS, 4,5-BIS-(TRIMETHYLSILYL)BENZOCYCLOBUTENE, A HIGHLY STRAINED, VERSATILE SYNTHETIC INTERMEDIATE Chemischer Informationsdienst. 6: no-no. DOI: 10.1002/Chin.197549349  0.355
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