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David M. Yurek, Ph.D. - Publications

Affiliations: 
University of Kentucky, Lexington, KY 
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42/48 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Ghosh B, Zhang C, Ziemba KS, Fletcher AM, Yurek DM, Smith GM. Partial Reconstruction of the Nigrostriatal Circuit along a Preformed Molecular Guidance Pathway. Molecular Therapy. Methods & Clinical Development. 14: 217-227. PMID 31417940 DOI: 10.1016/J.Omtm.2019.06.008  0.473
2017 Yurek DM, Hasselrot U, Sesenoglu-Laird O, Padegimas L, Cooper MJ. Intracerebral injections of DNA nanoparticles encoding for a therapeutic gene provide partial neuroprotection in an animal model of neurodegeneration. Nanomedicine : Nanotechnology, Biology, and Medicine. PMID 28666950 DOI: 10.1016/J.Nano.2017.06.010  0.483
2015 Yurek DM, Hasselrot U, Cass WA, Sesenoglu-Laird O, Padegimas L, Cooper MJ. Age and lesion-induced increases of GDNF transgene expression in brain following intracerebral injections of DNA nanoparticles. Neuroscience. 284: 500-12. PMID 25453772 DOI: 10.1016/J.Neuroscience.2014.10.026  0.43
2014 Cass WA, Peters LE, Fletcher AM, Yurek DM. Calcitriol promotes augmented dopamine release in the lesioned striatum of 6-hydroxydopamine treated rats. Neurochemical Research. 39: 1467-76. PMID 24858239 DOI: 10.1007/S11064-014-1331-1  0.553
2013 Zhang C, Jin Y, Ziemba KS, Fletcher AM, Ghosh B, Truit E, Yurek DM, Smith GM. Long distance directional growth of dopaminergic axons along pathways of netrin-1 and GDNF. Experimental Neurology. 250: 156-64. PMID 24099728 DOI: 10.1016/J.Expneurol.2013.09.022  0.348
2012 Cass WA, Peters LE, Fletcher AM, Yurek DM. Evoked dopamine overflow is augmented in the striatum of calcitriol treated rats. Neurochemistry International. 60: 186-91. PMID 22133428 DOI: 10.1016/J.Neuint.2011.11.010  0.535
2011 Fletcher AM, Kowalczyk TH, Padegimas L, Cooper MJ, Yurek DM. Transgene expression in the striatum following intracerebral injections of DNA nanoparticles encoding for human glial cell line-derived neurotrophic factor. Neuroscience. 194: 220-6. PMID 21839809 DOI: 10.1016/J.Neuroscience.2011.07.072  0.356
2011 Yurek DM, Fletcher AM, McShane M, Kowalczyk TH, Padegimas L, Weatherspoon MR, Kaytor MD, Cooper MJ, Ziady AG. DNA nanoparticles: detection of long-term transgene activity in brain using bioluminescence imaging. Molecular Imaging. 10: 327-39. PMID 21521549 DOI: 10.2310/7290.2010.00053  0.301
2010 Yurek DM, Fletcher AM, Peters LE, Cass WA. Strain difference in the up-regulation of FGF-2 protein following a neurotoxic lesion of the nigrostriatal pathway. Neurochemical Research. 35: 531-9. PMID 19921430 DOI: 10.1007/S11064-009-0093-7  0.343
2009 Yurek DM, Flectcher AM, Kowalczyk TH, Padegimas L, Cooper MJ. Compacted DNA nanoparticle gene transfer of GDNF to the rat striatum enhances the survival of grafted fetal dopamine neurons. Cell Transplantation. 18: 1183-96. PMID 19650971 DOI: 10.3727/096368909X12483162196881  0.614
2009 Yurek DM, Fletcher AM, Smith GM, Seroogy KB, Ziady AG, Molter J, Kowalczyk TH, Padegimas L, Cooper MJ. Long-term transgene expression in the central nervous system using DNA nanoparticles. Molecular Therapy : the Journal of the American Society of Gene Therapy. 17: 641-50. PMID 19223866 DOI: 10.1038/Mt.2009.2  0.333
2006 Smith MP, Fletcher-Turner A, Yurek DM, Cass WA. Calcitriol protection against dopamine loss induced by intracerebroventricular administration of 6-hydroxydopamine. Neurochemical Research. 31: 533-9. PMID 16758362 DOI: 10.1007/S11064-006-9048-4  0.55
2006 Tümer N, Scarpace PJ, Dogan MD, Broxson CS, Matheny M, Yurek DM, Peden CS, Burger C, Muzyczka N, Mandel RJ. Hypothalamic rAAV-mediated GDNF gene delivery ameliorates age-related obesity. Neurobiology of Aging. 27: 459-70. PMID 15964099 DOI: 10.1016/J.Neurobiolaging.2005.03.018  0.341
2005 Collier TJ, Dung Ling Z, Carvey PM, Fletcher-Turner A, Yurek DM, Sladek JR, Kordower JH. Striatal trophic factor activity in aging monkeys with unilateral MPTP-induced parkinsonism. Experimental Neurology. 191: S60-7. PMID 15629762 DOI: 10.1016/J.Expneurol.2004.08.018  0.674
2005 Yurek DM, Fletcher-Turner A, Cooper MJ. 655. Compacted DNA Nanoparticles Effectively Transfect Brain Cells In Vitro and In Vivo Molecular Therapy. 11. DOI: 10.1016/J.Ymthe.2005.07.195  0.334
2004 Zhang L, Fletcher-Turner A, Marchionni MA, Apparsundaram S, Lundgren KH, Yurek DM, Seroogy KB. Neurotrophic and neuroprotective effects of the neuregulin glial growth factor-2 on dopaminergic neurons in rat primary midbrain cultures. Journal of Neurochemistry. 91: 1358-68. PMID 15584912 DOI: 10.1111/J.1471-4159.2004.02817.X  0.564
2004 Yurek DM, Zhang L, Fletcher-Turner A, Seroogy KB. Supranigral injection of neuregulin1-beta induces striatal dopamine overflow. Brain Research. 1028: 116-9. PMID 15518649 DOI: 10.1016/J.Brainres.2004.08.066  0.55
2004 Yurek DM, Fletcher-Turner A. Comparison of embryonic stem cell-derived dopamine neuron grafts and fetal ventral mesencephalic tissue grafts: morphology and function. Cell Transplantation. 13: 295-306. PMID 15191167 DOI: 10.3727/000000004783983954  0.592
2003 Steece-Collier K, Collier TJ, Danielson PD, Kurlan R, Yurek DM, Sladek JR. Embryonic mesencephalic grafts increase levodopa-induced forelimb hyperkinesia in parkinsonian rats. Movement Disorders : Official Journal of the Movement Disorder Society. 18: 1442-54. PMID 14673880 DOI: 10.1002/Mds.10588  0.759
2002 Yurek DM, Fletcher-Turner A. Temporal changes in the neurotrophic environment of the denervated striatum as determined by the survival and outgrowth of grafted fetal dopamine neurons. Brain Research. 931: 126-34. PMID 11897098 DOI: 10.1016/S0006-8993(02)02258-8  0.6
2001 Yurek DM, Fletcher-Turner A, Moore J, Chai L, Mahanthappa N. Co-grafts of fetal ventral mesencephalon and fibroblasts expressing sonic hedgehog: effect on survival and function of dopamine grafts. Cell Transplantation. 10: 665-71. PMID 11814108 DOI: 10.3727/000000001783986305  0.59
2001 Dhillon HS, Dong GX, Yurek DM, Estus S, Rangnekar VM, Dendle P, Prasad RM. Regional expression of Par-4 mRNA and protein after fluid percussion brain injury in the rat. Experimental Neurology. 170: 140-8. PMID 11421591 DOI: 10.1006/Exnr.2001.7685  0.333
2001 Yurek DM, Fletcher-Turner A. Differential expression of GDNF, BDNF, and NT-3 in the aging nigrostriatal system following a neurotoxic lesion. Brain Research. 891: 228-35. PMID 11164827 DOI: 10.1016/S0006-8993(00)03217-0  0.429
2000 Yurek DM, Seroogy KB. Differential expression of neurotrophin and neurotrophin receptor mRNAs in and adjacent to fetal midbrain grafts implanted into the dopamine-denervated striatum. The Journal of Comparative Neurology. 423: 462-73. PMID 10870086 DOI: 10.1002/1096-9861(20000731)423:3<462::Aid-Cne9>3.0.Co;2-U  0.478
2000 Yurek DM, Fletcher-Turner A. Lesion-induced increase of BDNF is greater in the striatum of young versus old rat brain. Experimental Neurology. 161: 392-6. PMID 10683304 DOI: 10.1006/Exnr.1999.7274  0.425
1999 Yurek DM, Fletcher-Turner A. GDNF partially protects grafted fetal dopaminergic neurons against 6-hydroxydopamine neurotoxicity. Brain Research. 845: 21-7. PMID 10529440 DOI: 10.1016/S0006-8993(99)01921-6  0.557
1999 Zhang D, Dhillon HS, Mattson MP, Yurek DM, Prasad RM. Immunohistochemical detection of the lipid peroxidation product 4-hydroxynonenal after experimental brain injury in the rat. Neuroscience Letters. 272: 57-61. PMID 10507542 DOI: 10.1016/S0304-3940(99)00455-3  0.324
1998 Yurek DM. Glial cell line-derived neurotrophic factor improves survival of dopaminergic neurons in transplants of fetal ventral mesencephalic tissue. Experimental Neurology. 153: 195-202. PMID 9784279 DOI: 10.1006/Exnr.1998.6884  0.535
1998 Yurek DM, Hipkens SB, Wiegand SJ, Altar CA. Optimal effectiveness of BDNF for fetal nigral transplants coincides with the ontogenic appearance of BDNF in the striatum. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 18: 6040-7. PMID 9671688  0.451
1998 Yurek DM, Hipkens SB, Hebert MA, Gash DM, Gerhardt GA. Age-related decline in striatal dopamine release and motoric function in brown Norway/Fischer 344 hybrid rats. Brain Research. 791: 246-56. PMID 9593919 DOI: 10.1016/S0006-8993(98)00110-3  0.476
1997 Yurek DM. Intranigral transplants of fetal ventral mesencephalic tissue attenuate D1-agonist-induced rotational behavior. Experimental Neurology. 143: 1-9. PMID 9000440 DOI: 10.1006/Exnr.1996.6359  0.519
1996 Yurek DM, Lu W, Hipkens S, Wiegand SJ. BDNF enhances the functional reinnervation of the striatum by grafted fetal dopamine neurons. Experimental Neurology. 137: 105-18. PMID 8566202 DOI: 10.1006/Exnr.1996.0011  0.615
1995 Steece-Collier K, Yurek DM, Collier TJ, Junn FS, Sladek JR. The detrimental effect of levodopa on behavioral efficacy of fetal dopamine neuron grafts in rats is reversible following prolonged withdrawal of chronic dosing. Brain Research. 676: 404-8. PMID 7614013 DOI: 10.1016/0006-8993(95)00149-K  0.769
1994 Yurek DM, Hipkens SB. Intranigral injections of SCH 23390 inhibit SKF 82958-induced rotational behavior. Brain Research. 639: 329-32. PMID 7911393 DOI: 10.1016/0006-8993(94)91748-5  0.403
1993 Yurek DM, Hipkens SB. Intranigral injections of SCH 23390 inhibit amphetamine-induced rotational behavior. Brain Research. 623: 56-64. PMID 8221093 DOI: 10.1016/0006-8993(93)90009-C  0.469
1991 Yurek DM, Randall PK. Striatal depth EEG reveals postsynaptic activity of striatal neurons following dopamine receptor stimulation and blockade. Journal of Neuroscience Methods. 37: 81-91. PMID 2072738 DOI: 10.1016/0165-0270(91)90023-S  0.404
1991 Yurek DM, Steece-Collier K, Collier TJ, Sladek JR. Chronic levodopa impairs the recovery of dopamine agonist-induced rotational behavior following neural grafting. Experimental Brain Research. 86: 97-107. PMID 1684547 DOI: 10.1007/Bf00231044  0.755
1990 Yurek DM, Collier TJ, Sladek JR. Embryonic mesencephalic and striatal co-grafts: development of grafted dopamine neurons and functional recovery. Experimental Neurology. 109: 191-9. PMID 2379555 DOI: 10.1016/0014-4886(90)90073-2  0.761
1990 Yurek DM, Sladek JR. Dopamine cell replacement: Parkinson's disease. Annual Review of Neuroscience. 13: 415-40. PMID 2183683 DOI: 10.1146/Annurev.Ne.13.030190.002215  0.629
1990 Mandel RJ, Yurek DM, Randall PK. Behavioral demonstration of a reciprocal interaction between dopamine receptor subtypes in the mouse striatum: possible involvement of the striato-nigral pathway. Brain Research Bulletin. 25: 285-92. PMID 2146002 DOI: 10.1016/0361-9230(90)90073-9  0.42
1989 Yurek DM, Deutch AY, Roth RH, Sladek JR. Morphological, neurochemical, and behavioral characterizations associated with the combined treatment of diethyldithiocarbamate and 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine in mice. Brain Research. 497: 250-9. PMID 2573405 DOI: 10.1016/0006-8993(89)90270-9  0.642
1985 Yurek DM, Randall PK. Simultaneous catalepsy and apomorphine-induced stereotypic behavior in mice. Life Sciences. 37: 1665-73. PMID 4058245 DOI: 10.1016/0024-3205(85)90293-0  0.415
Low-probability matches (unlikely to be authored by this person)
2018 Aly AE, Harmon B, Padegimas L, Sesenoglu-Laird O, Cooper MJ, Yurek DM, Waszczak BL. Intranasal delivery of hGDNF plasmid DNA nanoparticles results in long-term and widespread transfection of perivascular cells in rat brain. Nanomedicine : Nanotechnology, Biology, and Medicine. PMID 30472323 DOI: 10.1016/J.Nano.2018.11.006  0.29
2001 Prasad RM, Doubinskaia I, Singh DK, Campbell G, Mace D, Fletcher A, Dendle P, Yurek DM, Scheff SW, Kraemer PJ. Effects of binge ethanol administration on the behavioral outcome of rats after lateral fluid percussion brain injury. Journal of Neurotrauma. 18: 1019-29. PMID 11686489 DOI: 10.1089/08977150152693719  0.285
1994 Prasad MR, Ramaiah C, McIntosh TK, Dempsey RJ, Hipkens S, Yurek D. Regional levels of lactate and norepinephrine after experimental brain injury. Journal of Neurochemistry. 63: 1086-94. PMID 8051549 DOI: 10.1046/J.1471-4159.1994.63031086.X  0.271
1999 Zhang D, Dhillon HS, Mattson MP, Yurek DM, Prasad RM. Practicable recovery of plasmids carrying cDNAs encoding anti-apoptotic factors that had been introduced by particle bombardment into 5-week-old rat hippocampal slices Neuroscience Letters. 272: 62-66. PMID 10507543 DOI: 10.1016/S0304-3940(99)00485-1  0.217
2016 Genin MJ, Gonzalez Valcercel IC, Holloway WG, Lamar J, Mosior M, Hawkins E, Estridge T, Weidner J, Seng T, Yurek D, Adams LA, Weller JM, Reynolds VL, Brozinick JT. Imidazopyridine and Pyrazolopiperidine Derivatives as Novel Inhibitors of Serine Palmitoyl Transferase. Journal of Medicinal Chemistry. PMID 27213958 DOI: 10.1021/acs.jmedchem.5b01851  0.124
2014 Yurek D, Yu L, Schrementi J, Bell MG, McGee J, Kowala M, Kuo MS, Wang J. Development of a high-throughput assay for aldosterone synthase inhibitors using high-performance liquid chromatography-tandem mass spectrometry. Analytical Biochemistry. 462: 44-50. PMID 24959941 DOI: 10.1016/J.Ab.2014.06.011  0.054
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