Kunhong Xiao - Publications

Affiliations: 
Department of Medicine Duke Medical School, Durham, NC, United States 

32 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2014 Shukla AK, Westfield GH, Xiao K, Reis RI, Huang LY, Tripathi-Shukla P, Qian J, Li S, Blanc A, Oleskie AN, Dosey AM, Su M, Liang CR, Gu LL, Shan JM, et al. Visualization of arrestin recruitment by a G-protein-coupled receptor. Nature. 512: 218-22. PMID 25043026 DOI: 10.1038/nature13430  0.6
2014 Kahsai AW, Rajagopal S, Sun J, Xiao K. Monitoring protein conformational changes and dynamics using stable-isotope labeling and mass spectrometry. Nature Protocols. 9: 1301-19. PMID 24810039 DOI: 10.1038/nprot.2014.075  0.6
2014 Brady DC, Crowe MS, Turski ML, Hobbs GA, Yao X, Chaikuad A, Knapp S, Xiao K, Campbell SL, Thiele DJ, Counter CM. Copper is required for oncogenic BRAF signalling and tumorigenesis. Nature. 509: 492-6. PMID 24717435 DOI: 10.1038/nature13180  0.6
2014 Wisler JW, Xiao K, Thomsen AR, Lefkowitz RJ. Recent developments in biased agonism. Current Opinion in Cell Biology. 27: 18-24. PMID 24680426 DOI: 10.1016/j.ceb.2013.10.008  0.6
2014 Files DC, Xiao K, Zhang T, Liu C, Qian J, Zhao W, Morris PE, Delbono O, Feng X. The posterior cricoarytenoid muscle is spared from MuRF1-mediated muscle atrophy in mice with acute lung injury. Plos One. 9: e87587. PMID 24498144 DOI: 10.1371/journal.pone.0087587  0.6
2013 Shukla AK, Manglik A, Kruse AC, Xiao K, Reis RI, Tseng WC, Staus DP, Hilger D, Uysal S, Huang LY, Paduch M, Tripathi-Shukla P, Koide A, Koide S, Weis WI, et al. Structure of active β-arrestin-1 bound to a G-protein-coupled receptor phosphopeptide. Nature. 497: 137-41. PMID 23604254 DOI: 10.1038/nature12120  0.6
2013 Tang H, Xiao K, Mao L, Rockman HA, Marchuk DA. Overexpression of TNNI3K, a cardiac-specific MAPKKK, promotes cardiac dysfunction. Journal of Molecular and Cellular Cardiology. 54: 101-11. PMID 23085512 DOI: 10.1016/j.yjmcc.2012.10.004  0.6
2012 Han SO, Xiao K, Kim J, Wu JH, Wisler JW, Nakamura N, Freedman NJ, Shenoy SK. MARCH2 promotes endocytosis and lysosomal sorting of carvedilol-bound β(2)-adrenergic receptors. The Journal of Cell Biology. 199: 817-30. PMID 23166351 DOI: 10.1083/jcb.201208192  0.76
2012 Xiao K, Sun J, Kim J, Rajagopal S, Zhai B, Villén J, Haas W, Kovacs JJ, Shukla AK, Hara MR, Hernandez M, Lachmann A, Zhao S, Lin Y, Cheng Y, et al. Global phosphorylation analysis of β-arrestin-mediated signaling downstream of a seven transmembrane receptor (7TMR) (Proceedings of the National Academy of Sciences of the United States of America (2010) 107, 34 (15299-15304) doi:10.1073/pnas.1008461107) Proceedings of the National Academy of Sciences of the United States of America. 109: 13464. DOI: 10.1073/pnas.1211889109  0.6
2011 Sarker S, Xiao K, Shenoy SK. A tale of two sites: How ubiquitination of a G protein-coupled receptor is coupled to its lysosomal trafficking from distinct receptor domains. Communicative & Integrative Biology. 4: 528-31. PMID 22046454 DOI: 10.4161/cib.4.5.16458  0.76
2011 Nobles KN, Xiao K, Ahn S, Shukla AK, Lam CM, Rajagopal S, Strachan RT, Huang TY, Bressler EA, Hara MR, Shenoy SK, Gygi SP, Lefkowitz RJ. Distinct phosphorylation sites on the β(2)-adrenergic receptor establish a barcode that encodes differential functions of β-arrestin. Science Signaling. 4: ra51. PMID 21868357 DOI: 10.1126/scisignal.2001707  0.6
2011 Hara MR, Kovacs JJ, Whalen EJ, Rajagopal S, Strachan RT, Grant W, Towers AJ, Williams B, Lam CM, Xiao K, Shenoy SK, Gregory SG, Ahn S, Duckett DR, Lefkowitz RJ. A stress response pathway regulates DNA damage through β2-adrenoreceptors and β-arrestin-1. Nature. 477: 349-53. PMID 21857681 DOI: 10.1038/nature10368  0.6
2011 Kahsai AW, Xiao K, Rajagopal S, Ahn S, Shukla AK, Sun J, Oas TG, Lefkowitz RJ. Multiple ligand-specific conformations of the β2-adrenergic receptor. Nature Chemical Biology. 7: 692-700. PMID 21857662 DOI: 10.1038/nchembio.634  0.6
2011 Shukla AK, Xiao K, Lefkowitz RJ. Emerging paradigms of β-arrestin-dependent seven transmembrane receptor signaling. Trends in Biochemical Sciences. 36: 457-69. PMID 21764321 DOI: 10.1016/j.tibs.2011.06.003  0.6
2011 Xiao K, Shenoy SK. β2-adrenergic receptor lysosomal trafficking is regulated by ubiquitination of lysyl residues in two distinct receptor domains Journal of Biological Chemistry. 286: 12785-12795. PMID 21330366 DOI: 10.1074/jbc.M110.203091  0.6
2011 Sarker S, Xiao K, Shenoy SK. A tale of two sites: How ubiquitination of a G protein-coupled receptor is coupled to its lysosomal trafficking from distinct receptor domains Communicative and Integrative Biology. 4: 528-531. DOI: 10.4161/cib.4.5.16458  0.6
2010 Hernandez M, Lachmann A, Zhao S, Xiao K, Ma'ayan A. Inferring the Sign of Kinase-Substrate Interactions by Combining Quantitative Phosphoproteomics with a Literature-Based Mammalian Kinome Network. Proceedings / Annual Ieee International Symposium On Bioinformatics and Bioengineering (Bibe). Ieee International Symposium On Bioinformatics and Bioengineering. 2010: 180-184. PMID 21552464 DOI: 10.1109/BIBE.2010.75  0.6
2010 Xiao K, Sun J, Kim J, Rajagopal S, Zhai B, Villén J, Haas W, Kovacs JJ, Shukla AK, Hara MR, Hernandez M, Lachmann A, Zhao S, Lin Y, Cheng Y, et al. Global phosphorylation analysis of beta-arrestin-mediated signaling downstream of a seven transmembrane receptor (7TMR). Proceedings of the National Academy of Sciences of the United States of America. 107: 15299-304. PMID 20686112 DOI: 10.1073/pnas.1008461107  0.6
2010 Shukla AK, Kim J, Ahn S, Xiao K, Shenoy SK, Liedtke W, Lefkowitz RJ. Arresting a transient receptor potential (TRP) channel: beta-arrestin 1 mediates ubiquitination and functional down-regulation of TRPV4. The Journal of Biological Chemistry. 285: 30115-25. PMID 20650893 DOI: 10.1074/jbc.M110.141549  0.6
2009 Xie L, Xiao K, Whalen EJ, Forrester MT, Freeman RS, Fong G, Gygi SP, Lefkowitz RJ, Stamler JS. Oxygen-regulated beta(2)-adrenergic receptor hydroxylation by EGLN3 and ubiquitylation by pVHL. Science Signaling. 2: ra33. PMID 19584355 DOI: 10.1126/scisignal.2000444  0.6
2009 Shenoy SK, Modi AS, Shukla AK, Xiao K, Berthouze M, Ahn S, Wilkinson KD, Miller WE, Lefkowitz RJ. Beta-arrestin-dependent signaling and trafficking of 7-transmembrane receptors is reciprocally regulated by the deubiquitinase USP33 and the E3 ligase Mdm2. Proceedings of the National Academy of Sciences of the United States of America. 106: 6650-5. PMID 19363159 DOI: 10.1073/pnas.0901083106  0.6
2009 Petrotchenko EV, Xiao K, Cable J, Chen Y, Dokholyan NV, Borchers CH. BiPS, a photocleavable, isotopically coded, fluorescent cross-linker for structural proteomics. Molecular & Cellular Proteomics : McP. 8: 273-86. PMID 18838738 DOI: 10.1074/mcp.M800265-MCP200  0.6
2008 Shenoy SK, Xiao K, Venkataramanan V, Snyder PM, Freedman NJ, Weissman AM. Nedd4 mediates agonist-dependent ubiquitination, lysosomal targeting, and degradation of the beta2-adrenergic receptor. The Journal of Biological Chemistry. 283: 22166-76. PMID 18544533 DOI: 10.1074/jbc.M709668200  0.76
2008 Kovacs JJ, Whalen EJ, Liu R, Xiao K, Kim J, Chen M, Wang J, Chen W, Lefkowitz RJ. Beta-arrestin-mediated localization of smoothened to the primary cilium. Science (New York, N.Y.). 320: 1777-81. PMID 18497258 DOI: 10.1126/science.1157983  0.6
2007 Shenoy SK, Barak LS, Xiao K, Ahn S, Berthouze M, Shukla AK, Luttrell LM, Lefkowitz RJ. Ubiquitination of beta-arrestin links seven-transmembrane receptor endocytosis and ERK activation. The Journal of Biological Chemistry. 282: 29549-62. PMID 17666399 DOI: 10.1074/jbc.M700852200  0.6
2007 Xiao K, McClatchy DB, Shukla AK, Zhao Y, Chen M, Shenoy SK, Yates JR, Lefkowitz RJ. Functional specialization of beta-arrestin interactions revealed by proteomic analysis. Proceedings of the National Academy of Sciences of the United States of America. 104: 12011-6. PMID 17620599 DOI: 10.1073/pnas.0704849104  0.6
2007 Nobles KN, Guan Z, Xiao K, Oas TG, Lefkowitz RJ. The active conformation of beta-arrestin1: direct evidence for the phosphate sensor in the N-domain and conformational differences in the active states of beta-arrestins1 and -2. The Journal of Biological Chemistry. 282: 21370-81. PMID 17513300 DOI: 10.1074/jbc.M611483200  0.6
2006 Shenoy SK, Drake MT, Nelson CD, Houtz DA, Xiao K, Madabushi S, Reiter E, Premont RT, Lichtarge O, Lefkowitz RJ. beta-arrestin-dependent, G protein-independent ERK1/2 activation by the beta2 adrenergic receptor. The Journal of Biological Chemistry. 281: 1261-73. PMID 16280323 DOI: 10.1074/jbc.M506576200  0.6
2004 Xiao K, Shenoy SK, Nobles K, Lefkowitz RJ. Activation-dependent conformational changes in {beta}-arrestin 2. The Journal of Biological Chemistry. 279: 55744-53. PMID 15501822 DOI: 10.1074/jbc.M409785200  0.6
2003 Engstrom G, Rajagukguk R, Saunders AJ, Patel CN, Rajagukguk S, Merbitz-Zahradnik T, Xiao K, Pielak GJ, Trumpower B, Yu CA, Yu L, Durham B, Millett F. Design of a ruthenium-labeled cytochrome c derivative to study electron transfer with the cytochrome bc1 complex. Biochemistry. 42: 2816-24. PMID 12627947 DOI: 10.1021/bi027213g  0.6
2003 Xiao K, Engstrom G, Rajagukguk S, Yu CA, Yu L, Durham B, Millett F. Effect of famoxadone on photoinduced electron transfer between the iron-sulfur center and cytochrome c1 in the cytochrome bc1 complex. The Journal of Biological Chemistry. 278: 11419-26. PMID 12525495 DOI: 10.1074/jbc.M211620200  0.6
2002 Engstrom G, Xiao K, Yu CA, Yu L, Durham B, Millett F. Photoinduced electron transfer between the Rieske iron-sulfur protein and cytochrome c(1) in the Rhodobacter sphaeroides cytochrome bc(1) complex. Effects of pH, temperature, and driving force. The Journal of Biological Chemistry. 277: 31072-8. PMID 12045199 DOI: 10.1074/jbc.M202594200  0.6
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