Year |
Citation |
Score |
2023 |
Frangos ZJ, Wilson KA, Aitken HM, Cantwell Chater R, Vandenberg RJ, O'Mara ML. Membrane cholesterol regulates inhibition and substrate transport by the glycine transporter, GlyT2. Life Science Alliance. 6. PMID 36690444 DOI: 10.26508/lsa.202201708 |
0.316 |
|
2021 |
Fairweather SJ, Gupta V, Chitsaz M, Booth L, Brown MH, O'Mara ML. Coordination of Substrate Binding and Protonation in the MtrD Efflux Pump Controls the Functionally Rotating Transport Mechanism. Acs Infectious Diseases. PMID 33980014 DOI: 10.1021/acsinfecdis.1c00149 |
0.306 |
|
2020 |
Carey Hulyer AR, Briggs DA, O'Mara ML, Kerr ID, Harmer JR, Callaghan R. Cross-linking, DEER-spectroscopy and molecular dynamics confirm the inward facing state of P-glycoprotein in a lipid membrane. Journal of Structural Biology. 107513. PMID 32339763 DOI: 10.1016/J.Jsb.2020.107513 |
0.414 |
|
2019 |
Mostyn SN, Wilson KA, Schumann-Gillett A, Frangos ZJ, Shimmon S, Rawling T, Ryan RM, O'Mara ML, Vandenberg RJ. Identification of an allosteric binding site on the human glycine transporter, GlyT2, for bioactive lipid analgesics. Elife. 8. PMID 31621581 DOI: 10.7554/Elife.47150 |
0.382 |
|
2019 |
Chiou TT, Long P, Schumann-Gillett A, Kanamarlapudi V, Haas SA, Harvey K, O'Mara ML, De Blas AL, Kalscheuer VM, Harvey RJ. Mutation p.R356Q in the Collybistin Phosphoinositide Binding Site Is Associated With Mild Intellectual Disability. Frontiers in Molecular Neuroscience. 12: 60. PMID 30914922 DOI: 10.3389/Fnmol.2019.00060 |
0.323 |
|
2019 |
Mostyn SN, Wilson KA, Schumann-Gillett A, Frangos ZJ, Shimmon S, Rawling T, Ryan RM, O'Mara ML, Vandenberg RJ. Author response: Identification of an allosteric binding site on the human glycine transporter, GlyT2, for bioactive lipid analgesics Elife. DOI: 10.7554/Elife.47150.029 |
0.384 |
|
2017 |
Carland JE, Thomas M, Mostyn SN, Subramanian N, O'Mara ML, Ryan RM, Vandenberg RJ. Molecular Determinants for Substrate Interactions with the Glycine Transporter GlyT2. Acs Chemical Neuroscience. PMID 29120604 DOI: 10.1021/Acschemneuro.7B00407 |
0.422 |
|
2017 |
Anandan A, Evans GL, Condic-Jurkic K, O'Mara ML, John CM, Phillips NJ, Jarvis GA, Wills SS, Stubbs KA, Moraes I, Kahler CM, Vrielink A. Structure of a lipid A phosphoethanolamine transferase suggests how conformational changes govern substrate binding. Proceedings of the National Academy of Sciences of the United States of America. PMID 28193899 DOI: 10.1073/Pnas.1612927114 |
0.301 |
|
2016 |
Mittra R, Pavy M, Subramanian N, George AM, O'Mara ML, Kerr ID, Callaghan R. Location of contact residues in pharmacologically distinct drug binding sites on P-glycoprotein. Biochemical Pharmacology. PMID 27729218 DOI: 10.1016/J.Bcp.2016.10.002 |
0.392 |
|
2016 |
Subramanian N, Scopelliti AJ, Carland JE, Ryan RM, O'Mara ML, Vandenberg RJ. Correction: Identification of a 3rd Na+ Binding Site of the Glycine Transporter, GlyT2. Plos One. 11: e0159896. PMID 27434127 DOI: 10.1371/Journal.Pone.0159896 |
0.34 |
|
2015 |
Subramanian N, Schumann-Gillett A, Mark AE, O'Mara ML. Understanding the accumulation of P-glycoprotein substrates within cells: The effect of cholesterol on membrane partitioning. Biochimica Et Biophysica Acta. PMID 26724201 DOI: 10.1016/J.Bbamem.2015.12.025 |
0.345 |
|
2015 |
Deplazes E, Begg SL, van Wonderen JH, Campbell R, Kobe B, Paton JC, MacMillan F, McDevitt CA, O'Mara ML. Characterizing the conformational dynamics of metal-free PsaA using molecular dynamics simulations and electron paramagnetic resonance spectroscopy. Biophysical Chemistry. 207: 51-60. PMID 26379256 DOI: 10.1016/J.Bpc.2015.08.004 |
0.328 |
|
2015 |
Subramanian N, Condic-Jurkic K, Mark AE, O'Mara ML. Identification of Possible Binding Sites for Morphine and Nicardipine on the Multidrug Transporter P-Glycoprotein Using Umbrella Sampling Techniques. Journal of Chemical Information and Modeling. 55: 1202-17. PMID 25938863 DOI: 10.1021/ci5007382 |
0.337 |
|
2014 |
O'Mara ML, Mark AE. Structural characterization of two metastable ATP-bound states of P-glycoprotein Plos One. 9. PMID 24632881 DOI: 10.1371/journal.pone.0091916 |
0.339 |
|
2014 |
van Wonderen JH, McMahon RM, O'Mara ML, McDevitt CA, Thomson AJ, Kerr ID, MacMillan F, Callaghan R. The central cavity of ABCB1 undergoes alternating access during ATP hydrolysis. The Febs Journal. 281: 2190-201. PMID 24597976 DOI: 10.1111/Febs.12773 |
0.378 |
|
2014 |
Plumptre CD, Eijkelkamp BA, Morey JR, Behr F, Couñago RM, Ogunniyi AD, Kobe B, O'Mara ML, Paton JC, McDevitt CA. AdcA and AdcAII employ distinct zinc acquisition mechanisms and contribute additively to zinc homeostasis in Streptococcus pneumoniae. Molecular Microbiology. 91: 834-51. PMID 24428621 DOI: 10.1111/Mmi.12504 |
0.363 |
|
2014 |
Couñago RM, Ween MP, Begg SL, Bajaj M, Zuegg J, O'Mara ML, Cooper MA, McEwan AG, Paton JC, Kobe B, McDevitt CA. Imperfect coordination chemistry facilitates metal ion release in the Psa permease. Nature Chemical Biology. 10: 35-41. PMID 24212134 DOI: 10.1038/Nchembio.1382 |
0.318 |
|
2013 |
Jia Z, O'Mara ML, Zuegg J, Cooper MA, Mark AE. Vancomycin: ligand recognition, dimerization and super-complex formation. The Febs Journal. 280: 1294-307. PMID 23298227 DOI: 10.1111/Febs.12121 |
0.337 |
|
2013 |
Jia ZG, O'Mara ML, Zuegg J, Cooper M, Mark A. Erratum: The effect of environment on the recognition and binding of vancomycin to native and resistant forms of lipid II (Biophysical Journal (2011) 101 (2684-2692)) Biophysical Journal. 104: 516-516. DOI: 10.1016/J.Bpj.2012.12.031 |
0.32 |
|
2012 |
Fairweather SJ, Bröer A, O'Mara ML, Bröer S. Intestinal peptidases form functional complexes with the neutral amino acid transporter B(0)AT1. The Biochemical Journal. 446: 135-48. PMID 22677001 DOI: 10.1042/Bj20120307 |
0.359 |
|
2011 |
Jia Z, O'Mara ML, Zuegg J, Cooper MA, Mark AE. The effect of environment on the recognition and binding of vancomycin to native and resistant forms of lipid II. Biophysical Journal. 101: 2684-92. PMID 22261057 DOI: 10.1016/J.Bpj.2011.10.047 |
0.325 |
|
2009 |
Oancea G, O'Mara ML, Bennett WF, Tieleman DP, Abele R, Tampé R. Structural arrangement of the transmission interface in the antigen ABC transport complex TAP. Proceedings of the National Academy of Sciences of the United States of America. 106: 5551-6. PMID 19297616 DOI: 10.1073/Pnas.0811260106 |
0.409 |
|
2009 |
Procko E, O'Mara ML, Bennett WF, Tieleman DP, Gaudet R. The mechanism of ABC transporters: general lessons from structural and functional studies of an antigenic peptide transporter. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 23: 1287-302. PMID 19174475 DOI: 10.1096/Fj.08-121855 |
0.381 |
|
2008 |
Moussatova A, Kandt C, O'Mara ML, Tieleman DP. ATP-binding cassette transporters in Escherichia coli. Biochimica Et Biophysica Acta. 1778: 1757-71. PMID 18634750 DOI: 10.1016/J.Bbamem.2008.06.009 |
0.404 |
|
2007 |
Lawson J, O'Mara ML, Kerr ID. Structure-based interpretation of the mutagenesis database for the nucleotide binding domains of P-glycoprotein. Biochimica Et Biophysica Acta. 1778: 376-91. PMID 18035039 DOI: 10.1016/J.Bbamem.2007.10.021 |
0.383 |
|
2007 |
O'Mara ML, Tieleman DP. P-glycoprotein models of the apo and ATP-bound states based on homology with Sav1866 and MalK. Febs Letters. 581: 4217-22. PMID 17706648 DOI: 10.1016/J.Febslet.2007.07.069 |
0.357 |
|
2006 |
O'Mara M, Oakley A, Broer S. Mechanism and putative structure of B0-like neutral amino acid transporters The Journal of Membrane Biology. 213: 111-118. PMID 17417702 DOI: 10.1007/S00232-006-0879-3 |
0.363 |
|
2006 |
Oloo EO, Kandt C, O'Mara ML, Tieleman DP. Computer simulations of ABC transporter components. Biochemistry and Cell Biology = Biochimie Et Biologie Cellulaire. 84: 900-11. PMID 17215877 DOI: 10.1139/o06-182 |
0.301 |
|
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