Patrick Skelly - Publications

Affiliations: 
Infectious Disease and Global Health Tufts Cummings School of Veterinary Medicine 

46 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Pirovich DB, Da'dara AA, Skelly PJ. GLYCOLYTIC ENZYMES AS VACCINES AGAINST SCHISTOSOMIASIS: TESTING SCHISTOSOMA MANSONI PHOSPHOGLYCERATE MUTASE IN MICE. The Journal of Parasitology. 110: 96-105. PMID 38466806 DOI: 10.1645/23-7  0.727
2023 Skelly PJ, Da'dara AA. A novel, non-neuronal acetylcholinesterase of schistosome parasites is essential for definitive host infection. Frontiers in Immunology. 14: 1056469. PMID 36798133 DOI: 10.3389/fimmu.2023.1056469  0.477
2022 Skelly PJ, Nation CS, Da'Dara AA. Schistosoma mansoni and the purinergic halo. Trends in Parasitology. 38: 1080-1088. PMID 36182536 DOI: 10.1016/j.pt.2022.09.001  0.328
2022 Skelly PJ, Da'dara AA. Schistosome secretomes. Acta Tropica. 236: 106676. PMID 36113567 DOI: 10.1016/j.actatropica.2022.106676  0.374
2022 Pirovich DB, Da'dara AA, Skelly PJ. Schistosoma mansoni phosphoglycerate mutase: a glycolytic ectoenzyme with thrombolytic potential. Parasite (Paris, France). 29: 41. PMID 36083036 DOI: 10.1051/parasite/2022042  0.735
2022 Nation CS, Da'Dara AA, Skelly PJ. NAD-catabolizing ectoenzymes of Schistosoma mansoni. The Biochemical Journal. 479: 1165-1180. PMID 35593185 DOI: 10.1042/BCJ20210784  0.514
2021 Acharya S, Da'dara AA, Skelly PJ. Schistosome immunomodulators. Plos Pathogens. 17: e1010064. PMID 34969052 DOI: 10.1371/journal.ppat.1010064  0.349
2021 Pirovich DB, Da'dara AA, Skelly PJ. Multifunctional Fructose 1,6-Bisphosphate Aldolase as a Therapeutic Target. Frontiers in Molecular Biosciences. 8: 719678. PMID 34458323 DOI: 10.3389/fmolb.2021.719678  0.711
2020 Da'dara AA, Elzoheiry M, El-Beshbishi SN, Skelly PJ. Vitamin B6 Acquisition and Metabolism in . Frontiers in Immunology. 11: 622162. PMID 33613557 DOI: 10.3389/fimmu.2020.622162  0.451
2020 Nation CS, Da'Dara AA, Skelly PJ. The essential schistosome tegumental ectoenzyme SmNPP5 can block NAD-induced T cell apoptosis. Virulence. 11: 568-579. PMID 32441549 DOI: 10.1080/21505594.2020.1770481  0.406
2020 Nation CS, Da'dara AA, Marchant JK, Skelly PJ. Schistosome migration in the definitive host. Plos Neglected Tropical Diseases. 14: e0007951. PMID 32240157 DOI: 10.1371/journal.pntd.0007951  0.338
2020 Angeli A, Pinteala M, Maier SS, Simionescu BC, Da'dara AA, Skelly PJ, Supuran CT. Sulfonamide Inhibition Studies of an α-Carbonic Anhydrase from , a Platyhelminth Parasite Responsible for Schistosomiasis. International Journal of Molecular Sciences. 21. PMID 32155992 DOI: 10.3390/ijms21051842  0.326
2020 Pirovich DB, Da'dara AA, Skelly PJ. glyceraldehyde-3-phosphate dehydrogenase enhances formation of the blood-clot lysis protein plasmin. Biology Open. PMID 32098782 DOI: 10.1242/Bio.050385  0.734
2019 Da'dara AA, Angeli A, Ferraroni M, Supuran CT, Skelly PJ. Crystal structure and chemical inhibition of essential schistosome host-interactive virulence factor carbonic anhydrase SmCA. Communications Biology. 2: 333. PMID 31925135 DOI: 10.1038/s42003-019-0578-0  0.408
2019 Pirovich D, Da'dara AA, Skelly PJ. Why Do Intravascular Schistosomes Coat Themselves in Glycolytic Enzymes? Bioessays : News and Reviews in Molecular, Cellular and Developmental Biology. e1900103. PMID 31661165 DOI: 10.1002/Bies.201900103  0.733
2019 Da'dara AA, Angeli A, Ferraroni M, Supuran CT, Skelly PJ. Crystal structure and chemical inhibition of essential schistosome host-interactive virulence factor carbonic anhydrase SmCA. Communications Biology. 2: 333. PMID 31508507 DOI: 10.1038/s42003-019-0578-0  0.407
2019 Elzoheiry M, Da'dara AA, Nation CS, El-Beshbishi SN, Skelly PJ. Schistosomes can hydrolyze proinflammatory and prothrombotic polyphosphate (polyP) via tegumental alkaline phosphatase, SmAP. Molecular and Biochemical Parasitology. 111190. PMID 31154018 DOI: 10.1016/j.molbiopara.2019.111190  0.455
2018 Elzoheiry M, Da'dara AA, Bhardwaj R, Wang Q, Azab MS, El-Kholy EI, El-Beshbishi SN, Skelly PJ. Intravascular Cleave the Host Immune and Hemostatic Signaling Molecule Sphingosine-1-Phosphate Tegumental Alkaline Phosphatase. Frontiers in Immunology. 9: 1746. PMID 30105025 DOI: 10.3389/fimmu.2018.01746  0.415
2018 Elzoheiry M, Da'dara AA, deLaforcade AM, El-Beshbishi SN, Skelly PJ. The Essential Ectoenzyme SmNPP5 from the Human Intravascular Parasite Schistosoma mansoni is an ADPase and a Potent Inhibitor of Platelet Aggregation. Thrombosis and Haemostasis. PMID 29669386 DOI: 10.1055/s-0038-1641715  0.495
2017 Wang Q, Da'dara AA, Skelly PJ. The human blood parasite Schistosoma mansoni expresses extracellular tegumental calpains that cleave the blood clotting protein fibronectin. Scientific Reports. 7: 12912. PMID 29018227 DOI: 10.1038/s41598-017-13141-5  0.556
2015 Figueiredo BC, Da'dara AA, Oliveira SC, Skelly PJ. Schistosomes Enhance Plasminogen Activation: The Role of Tegumental Enolase. Plos Pathogens. 11: e1005335. PMID 26658895 DOI: 10.1371/journal.ppat.1005335  0.57
2014 Figueiredo BC, Assis NR, Morais SB, Ricci ND, Pinheiro CS, Martins VP, Bicalho RM, Da'dara AA, Skelly PJ, Oliveira SC. Schistosome syntenin partially protects vaccinated mice against Schistosoma mansoni infection. Plos Neglected Tropical Diseases. 8: e3107. PMID 25144756 DOI: 10.1371/journal.pntd.0003107  0.317
2014 Skelly PJ, Da'dara AA, Li XH, Castro-Borges W, Wilson RA. Schistosome feeding and regurgitation. Plos Pathogens. 10: e1004246. PMID 25121497 DOI: 10.1371/journal.ppat.1004246  0.317
2014 Da'dara AA, Bhardwaj R, Skelly PJ. Schistosome apyrase SmATPDase1, but not SmATPDase2, hydrolyses exogenous ATP and ADP. Purinergic Signalling. 10: 573-80. PMID 24894599 DOI: 10.1007/s11302-014-9416-5  0.425
2014 Da'dara AA, Bhardwaj R, Ali YB, Skelly PJ. Schistosome tegumental ecto-apyrase (SmATPDase1) degrades exogenous pro-inflammatory and pro-thrombotic nucleotides. Peerj. 2: e316. PMID 24711968 DOI: 10.7717/peerj.316  0.507
2012 Da'dara A, Krautz-Peterson G, Faghiri Z, Skelly PJ. Metabolite movement across the schistosome surface. Journal of Helminthology. 86: 141-7. PMID 22365312 DOI: 10.1017/S0022149X12000120  0.3
2011 Bhardwaj R, Krautz-Peterson G, Da'dara A, Tzipori S, Skelly PJ. Tegumental phosphodiesterase SmNPP-5 is a virulence factor for schistosomes. Infection and Immunity. 79: 4276-84. PMID 21825060 DOI: 10.1128/IAI.05431-11  0.442
2011 Da'dara A, Skelly PJ. Manipulation of vascular function by blood flukes? Blood Reviews. 25: 175-9. PMID 21543145 DOI: 10.1016/j.blre.2011.04.002  0.309
2011 Bhardwaj R, Skelly PJ. Characterization of schistosome tegumental alkaline phosphatase (SmAP). Plos Neglected Tropical Diseases. 5: e1011. PMID 21483710 DOI: 10.1371/journal.pntd.0001011  0.522
2010 Sepulveda J, Tremblay JM, DeGnore JP, Skelly PJ, Shoemaker CB. Schistosoma mansoni host-exposed surface antigens characterized by sera and recombinant antibodies from schistosomiasis-resistant rats. International Journal For Parasitology. 40: 1407-17. PMID 20600071 DOI: 10.1016/j.ijpara.2010.04.019  0.309
2010 Krautz-Peterson G, Simoes M, Faghiri Z, Ndegwa D, Oliveira G, Shoemaker CB, Skelly PJ. Suppressing glucose transporter gene expression in schistosomes impairs parasite feeding and decreases survival in the mammalian host. Plos Pathogens. 6: e1000932. PMID 20532163 DOI: 10.1371/journal.ppat.1000932  0.361
2010 Faghiri Z, Camargo SM, Huggel K, Forster IC, Ndegwa D, Verrey F, Skelly PJ. The tegument of the human parasitic worm Schistosoma mansoni as an excretory organ: the surface aquaporin SmAQP is a lactate transporter. Plos One. 5: e10451. PMID 20454673 DOI: 10.1371/journal.pone.0010451  0.327
2009 Bhardwaj R, Skelly PJ. Purinergic signaling and immune modulation at the schistosome surface? Trends in Parasitology. 25: 256-60. PMID 19423396 DOI: 10.1016/j.pt.2009.03.004  0.33
2009 Faghiri Z, Skelly PJ. The role of tegumental aquaporin from the human parasitic worm, Schistosoma mansoni, in osmoregulation and drug uptake. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 23: 2780-9. PMID 19364765 DOI: 10.1096/fj.09-130757  0.365
2009 Krautz-Peterson G, Ndegwa D, Vasquez K, Korideck H, Zhang J, Peterson JD, Skelly PJ. Imaging schistosomes in vivo. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 23: 2673-80. PMID 19346298 DOI: 10.1096/fj.08-127738  0.315
2009 Schroeder H, Skelly PJ, Zipfel PF, Losson B, Vanderplasschen A. Subversion of complement by hematophagous parasites. Developmental and Comparative Immunology. 33: 5-13. PMID 18762211 DOI: 10.1016/j.dci.2008.07.010  0.419
2008 Skelly P. Fighting killer worms. Scientific American. 298: 94-9. PMID 18444331 DOI: 10.1038/Scientificamerican0508-94  0.377
2008 Krautz-Peterson G, Skelly PJ. Schistosome asparaginyl endopeptidase (legumain) is not essential for cathepsin B1 activation in vivo. Molecular and Biochemical Parasitology. 159: 54-8. PMID 18280591 DOI: 10.1016/j.molbiopara.2007.12.011  0.448
2007 Ndegwa D, Krautz-Peterson G, Skelly PJ. Protocols for gene silencing in schistosomes. Experimental Parasitology. 117: 284-91. PMID 17870072 DOI: 10.1016/j.exppara.2007.07.012  0.304
2007 Krautz-Peterson G, Camargo S, Huggel K, Verrey F, Shoemaker CB, Skelly PJ. Amino acid transport in schistosomes: Characterization of the permeaseheavy chain SPRM1hc. The Journal of Biological Chemistry. 282: 21767-75. PMID 17545149 DOI: 10.1074/jbc.M703512200  0.333
2006 Keating JH, Wilson RA, Skelly PJ. No overt cellular inflammation around intravascular schistosomes in vivo. The Journal of Parasitology. 92: 1365-9. PMID 17304823 DOI: 10.1645/GE-864R.1  0.347
2006 Skelly PJ, Alan Wilson R. Making sense of the schistosome surface. Advances in Parasitology. 63: 185-284. PMID 17134654 DOI: 10.1016/S0065-308X(06)63003-0  0.38
2004 Skelly PJ. Intravascular schistosomes and complement. Trends in Parasitology. 20: 370-4. PMID 15246320 DOI: 10.1016/j.pt.2004.05.007  0.303
2004 Dalton JP, Skelly P, Halton DW. Role of the tegument and gut in nutrient uptake by parasitic platyhelminths Canadian Journal of Zoology. 82: 211-232. DOI: 10.1139/Z03-213  0.487
2001 Skelly PJ, Shoemaker CB. Schistosoma mansoni proteases Sm31 (cathepsin B) and Sm32 (legumain) are expressed in the cecum and protonephridia of cercariae. The Journal of Parasitology. 87: 1218-21. PMID 11695408 DOI: 10.1645/0022-3395(2001)087[1218:SMPSCB]2.0.CO;2  0.307
1998 Harn DA, Reynolds SR, Chikunguwo S, Dissayanake S, Skelly P, Shoemaker C, Okano M. Peptide and DNA vaccines for schistosomiasis, and discovery of a novel adjuvant that promotes antibody responses Parasitology International. 47: 14. DOI: 10.1016/S1383-5769(98)80006-8  0.301
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