| Year |
Citation |
Score |
| 2023 |
McRae SW, Cleary M, DeRoche D, Martinez FM, Xia Y, Caravan P, Gale EM, Ronald JA, Scholl TJ. Development of a Suite of Gadolinium-Free OATP1-Targeted Paramagnetic Probes for Liver MRI. Journal of Medicinal Chemistry. PMID 37159947 DOI: 10.1021/acs.jmedchem.2c01561 |
0.322 |
|
| 2020 |
Shuvaev S, Suturina EA, Rotile NJ, Astashkin A, Ziegler CJ, Ross AW, Walker TL, Caravan P, Taschner IS. Revisiting dithiadiaza macrocyclic chelators for copper-64 PET imaging. Dalton Transactions (Cambridge, England : 2003). PMID 32970072 DOI: 10.1039/D0Dt02787A |
0.315 |
|
| 2020 |
Le Fur M, Zhou IY, Catalano O, Caravan P. Toward Molecular Imaging of Intestinal Pathology. Inflammatory Bowel Diseases. PMID 32793946 DOI: 10.1093/Ibd/Izaa213 |
0.306 |
|
| 2020 |
Zhou IY, Tanabe KK, Fuchs BC, Caravan P. Collagen-targeted molecular imaging in diffuse liver diseases. Abdominal Radiology (New York). PMID 32737546 DOI: 10.1007/S00261-020-02677-2 |
0.319 |
|
| 2020 |
Akam EA, Abston E, Rotile NJ, Slattery HR, Zhou IY, Lanuti M, Caravan P. Improving the reactivity of hydrazine-bearing MRI probes for imaging of lung fibrogenesis. Chemical Science. 11: 224-231. PMID 32728411 DOI: 10.1039/C9Sc04821A |
0.304 |
|
| 2020 |
Erstad DJ, Sojoodi M, Taylor MS, Clavijo Jordan V, Farrar CT, Axtell AL, Rotile NJ, Jones C, Graham-O'Regan KA, Ferreira DS, Michelakos T, Kontos F, Chawla A, Li S, Ghoshal S, ... ... Caravan P, et al. Fibrotic Response to Neoadjuvant Therapy Predicts Survival in Pancreatic Cancer and is Measurable with Collagen-Targeted Molecular MRI. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 32611647 DOI: 10.1158/1078-0432.Ccr-18-1359 |
0.315 |
|
| 2020 |
Zhou IY, Catalano OA, Caravan P. Advances in Functional and Molecular MRI Technologies in Chronic Liver Diseases. Journal of Hepatology. PMID 32585160 DOI: 10.1016/J.Jhep.2020.06.020 |
0.35 |
|
| 2020 |
Gupta A, Caravan P, Price WS, Platas-Iglesias C, Gale EM. Applications for Transition-Metal Chemistry in Contrast-Enhanced Magnetic Resonance Imaging. Inorganic Chemistry. PMID 32367714 DOI: 10.1021/Acs.Inorgchem.0C00510 |
0.359 |
|
| 2020 |
Frenk NE, Montesi SB, Chen T, Liang LL, Zhou I, Seethamraju R, Caravan P, Digumarthy SR. Free-breathing dynamic contrast-enhanced magnetic resonance of interstitial lung fibrosis. Magnetic Resonance Imaging. PMID 32126265 DOI: 10.1016/J.Mri.2020.02.014 |
0.314 |
|
| 2019 |
Atanasova I, Sojoodi M, Leitão HS, Shuvaev S, Geraldes CFGC, Masia R, Guimaraes AS, Tanabe KK, Fuchs BC, Caravan P. Molecular Magnetic Resonance Imaging of Fibrin Deposition in the Liver as an Indicator of Tissue Injury and Inflammation. Investigative Radiology. PMID 31895219 DOI: 10.1097/Rli.0000000000000631 |
0.307 |
|
| 2019 |
Le Fur M, Rotile NJ, Correcher C, Clavijo-Jordan V, Ross AW, Catana C, Caravan P. Yttrium-86 is a Positron Emitting Surrogate of Gadolinium for Noninvasive Quantification of Whole-Body Distribution of Gadolinium-Based Contrast Agents. Angewandte Chemie (International Ed. in English). PMID 31750991 DOI: 10.1002/Anie.201911858 |
0.372 |
|
| 2019 |
Rodríguez-Rodríguez A, Shuvaev S, Rotile N, Jones C, Probst C, Dos Santos Ferreira D, Graham-O'Regan K, Boros E, Knipe RS, Griffith J, Tager AM, Bogdanov AA, Caravan P. Peroxidase Sensitive Amplifiable Probe for Molecular Magnetic Resonance Imaging of Pulmonary Inflammation. Acs Sensors. PMID 31397156 DOI: 10.1021/Acssensors.9B01010 |
0.729 |
|
| 2019 |
Erstad DJ, Ramsay IA, Jordan VC, Sojoodi M, Fuchs BC, Tanabe KK, Caravan P, Gale EM. Tumor Contrast Enhancement and Whole-Body Elimination of the Manganese-Based Magnetic Resonance Imaging Contrast Agent Mn-PyC3A. Investigative Radiology. PMID 31356382 DOI: 10.1097/Rli.0000000000000593 |
0.373 |
|
| 2019 |
Caravan P, Esteban-Gómez D, Rodríguez-Rodríguez A, Platas-Iglesias C. Water exchange in lanthanide complexes for MRI applications. Lessons learned over the last 25 years. Dalton Transactions (Cambridge, England : 2003). PMID 31241112 DOI: 10.1039/C9Dt01948K |
0.407 |
|
| 2019 |
Montesi SB, Caravan P. Novel Imaging Approaches in Systemic Sclerosis-Associated Interstitial Lung Disease. Current Rheumatology Reports. 21: 25. PMID 31025121 DOI: 10.1007/S11926-019-0826-9 |
0.321 |
|
| 2019 |
Wang H, Clavijo Jordan V, Ramsay IA, Sojoodi M, Fuchs BC, Tanabe KK, Caravan P, Gale EM. Molecular Magnetic Resonance Imaging Using a Redox Active Iron Complex. Journal of the American Chemical Society. PMID 30874437 DOI: 10.1021/Jacs.9B00603 |
0.34 |
|
| 2019 |
Montesi SB, Désogère P, Fuchs BC, Caravan P. Molecular imaging of fibrosis: recent advances and future directions. The Journal of Clinical Investigation. 129: 24-33. PMID 30601139 DOI: 10.1172/Jci122132 |
0.317 |
|
| 2019 |
Izquierdo-Garcia D, Diyabalanage H, Ramsay I, Rotile N, Choi J, Witzel T, Humblet V, Brownell A, Catana C, Caravan P, Ay I. Abstract WP526: Molecular Imaging of Carotid Plaques Using a Fibrin-Binding PET Probe Stroke. 50. DOI: 10.1161/Str.50.Suppl_1.Wp526 |
0.326 |
|
| 2018 |
Le Fur M, Caravan P. The biological fate of gadolinium-based MRI contrast agents: a call to action for bioinorganic chemists. Metallomics : Integrated Biometal Science. PMID 30516229 DOI: 10.1039/C8Mt00302E |
0.354 |
|
| 2018 |
Wahsner J, Gale EM, Rodríguez-Rodríguez A, Caravan P. Chemistry of MRI Contrast Agents: Current Challenges and New Frontiers. Chemical Reviews. PMID 30350585 DOI: 10.1021/Acs.Chemrev.8B00363 |
0.377 |
|
| 2018 |
Wang J, Wang H, Ramsay I, Erstad DJ, Fuchs B, Tanabe K, Caravan P, Gale EM. Manganese-Based Contrast Agents for Magnetic Resonance Imaging of Liver Tumors: Structure Activity Relationships and Lead Candidate Evaluation. Journal of Medicinal Chemistry. PMID 30204438 DOI: 10.1021/Acs.Jmedchem.8B00964 |
0.371 |
|
| 2018 |
Desogere P, Montesi SB, Caravan P. Molecular Probes for Imaging Fibrosis and Fibrogenesis. Chemistry (Weinheim An Der Bergstrasse, Germany). PMID 30014529 DOI: 10.1002/Chem.201801578 |
0.348 |
|
| 2018 |
Wadghiri YZ, Hoang DM, Leporati A, Gounis MJ, Rodríguez-Rodríguez A, Mazzanti ML, Weaver JP, Wakhloo AK, Caravan P, Bogdanov AA. High-resolution Imaging of Myeloperoxidase Activity Sensors in Human Cerebrovascular Disease. Scientific Reports. 8: 7687. PMID 29769642 DOI: 10.1038/S41598-018-25804-Y |
0.322 |
|
| 2018 |
Boros E, Pinkhasov OR, Caravan P. Metabolite profiling with HPLC-ICP-MS as a tool for in vivo characterization of imaging probes. Ejnmmi Radiopharmacy and Chemistry. 3: 2. PMID 29503859 DOI: 10.1186/S41181-017-0037-5 |
0.698 |
|
| 2018 |
Dai L, Jones CM, Chan WTK, Pham TA, Ling X, Gale EM, Rotile NJ, Tai WC, Anderson CJ, Caravan P, Law GL. Chiral DOTA chelators as an improved platform for biomedical imaging and therapy applications. Nature Communications. 9: 857. PMID 29487362 DOI: 10.1038/S41467-018-03315-8 |
0.406 |
|
| 2018 |
Gale EM, Caravan P. Gadolinium-Free Contrast Agents for Magnetic Resonance Imaging of the Central Nervous System. Acs Chemical Neuroscience. PMID 29431424 DOI: 10.1021/Acschemneuro.8B00044 |
0.357 |
|
| 2018 |
Izquierdo-Garcia D, Diyabalanage H, Ramsay I, Rotile NJ, Mauskapf A, Choi J, Witzel T, Humblet V, Brownell A, Catana C, Caravan P, Ay I. Abstract 324: Molecular Imaging of High Risk Atherosclerotic Plaque Using Fibrin-Binding PET Probe Arteriosclerosis, Thrombosis, and Vascular Biology. 38. DOI: 10.1161/Atvb.38.Suppl_1.324 |
0.309 |
|
| 2018 |
Erstad DJ, Ramsay I, Sojoodi M, Farrar C, Rotile NJ, Li S, Ghoshal S, Michael L, Caravan P, Tanabe KK, Fuchs BC, Gale E. Abstract 659: A novel manganese MRI contrast agent (PyC3A) for the evaluation of hepatic neoplasms Cancer Research. 78: 659-659. DOI: 10.1158/1538-7445.Am2018-659 |
0.367 |
|
| 2017 |
Farrar CT, Gale EM, Kennan R, Ramsay I, Masia R, Arora G, Looby K, Wei L, Kalpathy-Cramer J, Bunzel MM, Zhang C, Zhu Y, Akiyama TE, Klimas M, Pinto S, ... ... Caravan P, et al. CM-101: Type I Collagen-targeted MR Imaging Probe for Detection of Liver Fibrosis. Radiology. 170595. PMID 29156148 DOI: 10.1148/Radiol.2017170595 |
0.312 |
|
| 2017 |
Gale EM, Wey HY, Ramsay I, Yen YF, Sosnovik DE, Caravan P. A Manganese-based Alternative to Gadolinium: Contrast-enhanced MR Angiography, Excretion, Pharmacokinetics, and Metabolism. Radiology. 170977. PMID 29117483 DOI: 10.1148/Radiol.2017170977 |
0.331 |
|
| 2017 |
Oliveira BL, Caravan P. Peptide-based fibrin-targeting probes for thrombus imaging. Dalton Transactions (Cambridge, England : 2003). PMID 29051933 DOI: 10.1039/C7Dt02634J |
0.371 |
|
| 2017 |
Polasek M, Yang Y, Schühle DT, Yaseen MA, Kim YR, Sung YS, Guimaraes AR, Caravan P. Molecular MR imaging of fibrosis in a mouse model of pancreatic cancer. Scientific Reports. 7: 8114. PMID 28808290 DOI: 10.1038/S41598-017-08838-6 |
0.359 |
|
| 2017 |
Waghorn PA, Jones CM, Rotile NJ, Koerner SK, Ferreira DS, Chen HH, Probst CK, Tager AM, Caravan P. Molecular Magnetic Resonance Imaging of Lung Fibrogenesis with an Oxyamine Based Probe. Angewandte Chemie (International Ed. in English). PMID 28677860 DOI: 10.1002/Anie.201704773 |
0.335 |
|
| 2017 |
Désogère P, Tapias LF, Rietz TA, Rotile N, Blasi F, Day H, Elliot J, Fuchs BC, Lanuti M, Caravan P. Optimization of a collagen-targeted positron emission tomography probe for molecular imaging of pulmonary fibrosis. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. PMID 28611243 DOI: 10.2967/Jnumed.117.193532 |
0.331 |
|
| 2017 |
Chen HH, Waghorn PA, Wei L, Tapias LF, Schu Hle DT, Rotile NJ, Jones CM, Looby RJ, Zhao G, Elliott JM, Probst CK, Mino-Kenudson M, Lauwers GY, Tager AM, Tanabe KK, ... ... Caravan P, et al. Molecular imaging of oxidized collagen quantifies pulmonary and hepatic fibrogenesis. Jci Insight. 2. PMID 28570270 DOI: 10.1172/Jci.Insight.91506 |
0.321 |
|
| 2017 |
Gale EM, Caravan P, Rao AG, McDonald RJ, Winfeld M, Fleck RJ, Gee MS. Gadolinium-based contrast agents in pediatric magnetic resonance imaging. Pediatric Radiology. 47: 507-521. PMID 28409250 DOI: 10.1007/S00247-017-3806-0 |
0.356 |
|
| 2017 |
Boros E, Srinivas R, Kim HK, Raitsimring AM, Astashkin AV, Poluektov OG, Niklas J, Horning AD, Tidor B, Caravan P. Intramolecular Hydrogen Bonding Restricts Gd-Aqua-Ligand Dynamics. Angewandte Chemie (International Ed. in English). PMID 28398613 DOI: 10.1002/Anie.201702274 |
0.729 |
|
| 2016 |
Zhu B, Wei L, Rotile N, Day H, Rietz T, Farrar CT, Lauwers GY, Tanabe KK, Rosen B, Fuchs BC, Caravan P. Combined magnetic resonance elastography and collagen molecular magnetic resonance imaging accurately stage liver fibrosis in a rat model. Hepatology (Baltimore, Md.). PMID 28039886 DOI: 10.1002/Hep.28930 |
0.333 |
|
| 2016 |
Gale EM, Jones CM, Ramsay I, Farrar CT, Caravan P. A Janus Chelator Enables Biochemically Responsive MRI Contrast with Exceptional Dynamic Range. Journal of the American Chemical Society. 138: 15861-15864. PMID 27960350 DOI: 10.1021/Jacs.6B10898 |
0.349 |
|
| 2016 |
Boros E, Holland JP, Kenton N, Rotile N, Caravan P. Macrocycle-Based Hydroxamate Ligands for Complexation and Immunoconjugation of (89)Zirconium for Positron Emission Tomography (PET) Imaging. Chempluschem. 81: 274-281. PMID 27630807 DOI: 10.1002/Cplu.201600003 |
0.736 |
|
| 2016 |
Iki N, Boros E, Nakamura M, Baba R, Caravan P. Gd3TCAS2: An Aquated Gd(3+)-Thiacalix[4]arene Sandwich Cluster with Extremely Slow Ligand Substitution Kinetics. Inorganic Chemistry. PMID 27018719 DOI: 10.1021/Acs.Inorgchem.6B00241 |
0.743 |
|
| 2016 |
Boros E, Holland JP, Kenton N, Rotile N, Caravan P. Macrocycle-Based Hydroxamate Ligands for Complexation and Immunoconjugation of 89Zirconium for Positron Emission Tomography (PET) Imaging Chempluschem. 81: 274-281. DOI: 10.1002/cplu.201600003 |
0.723 |
|
| 2015 |
Meimetis LG, Boros E, Carlson JC, Ran C, Caravan P, Weissleder R. Bioorthogonal fluorophore linked DFO - Technology enabling facile chelator quantification and multimodal imaging of antibodies. Bioconjugate Chemistry. PMID 26684717 DOI: 10.1021/Acs.Bioconjchem.5B00630 |
0.727 |
|
| 2015 |
Gale EM, Atanasova IP, Blasi F, Ay I, Caravan P. A Manganese Alternative to Gadolinium for MRI Contrast. Journal of the American Chemical Society. 137: 15548-57. PMID 26588204 DOI: 10.1021/Jacs.5B10748 |
0.392 |
|
| 2015 |
Blasi F, Oliveira BL, Rietz TA, Rotile NJ, Naha PC, Cormode DP, Izquierdo-Garcia D, Catana C, Caravan P. Multisite Thrombus Imaging and Fibrin Content Estimation With a Single Whole-Body PET Scan in Rats. Arteriosclerosis, Thrombosis, and Vascular Biology. PMID 26272938 DOI: 10.1161/Atvbaha.115.306055 |
0.324 |
|
| 2015 |
Oliveira BL, Blasi F, Rietz TA, Rotile NJ, Day H, Caravan P. Multimodal Molecular Imaging Reveals High Target Uptake and Specificity of 111In- and 68Ga-Labeled Fibrin-Binding Probes for Thrombus Detection in Rats. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. 56: 1587-92. PMID 26251420 DOI: 10.2967/Jnumed.115.160754 |
0.364 |
|
| 2015 |
Blasi F, Oliveira BL, Rietz TA, Rotile NJ, Day H, Naha PC, Cormode DP, Izquierdo-Garcia D, Catana C, Caravan P. Radiation dosimetry of the fibrin-binding probe 64Cu-FBP8 and its feasibility for positron emission tomography imaging of deep vein thrombosis and pulmonary embolism in rats. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. PMID 25977464 DOI: 10.2967/Jnumed.115.157982 |
0.303 |
|
| 2015 |
Boros E, Caravan P. Probing the structure-relaxivity relationship of bis-hydrated Gd(DOTAla) derivatives Inorganic Chemistry. 54: 2403-2410. PMID 25693053 DOI: 10.1021/Ic503035F |
0.75 |
|
| 2015 |
Boros E, Gale EM, Caravan P. MR imaging probes: Design and applications Dalton Transactions. 44: 4804-4818. PMID 25376893 DOI: 10.1039/C4Dt02958E |
0.723 |
|
| 2014 |
Gale EM, Mukherjee S, Liu C, Loving GS, Caravan P. Structure-redox-relaxivity relationships for redox responsive manganese-based magnetic resonance imaging probes. Inorganic Chemistry. 53: 10748-61. PMID 25226090 DOI: 10.1021/Ic502005U |
0.383 |
|
| 2014 |
Zhu J, Gale EM, Atanasova I, Rietz TA, Caravan P. Hexameric Mn(II) dendrimer as MRI contrast agent. Chemistry (Weinheim An Der Bergstrasse, Germany). 20: 14507-13. PMID 25224391 DOI: 10.1002/Chem.201403883 |
0.382 |
|
| 2014 |
Boros E, Karimi S, Kenton N, Helm L, Caravan P. Gd(DOTAlaP): exploring the boundaries of fast water exchange in gadolinium-based magnetic resonance imaging contrast agents. Inorganic Chemistry. 53: 6985-94. PMID 24922178 DOI: 10.1021/Ic5008928 |
0.755 |
|
| 2014 |
Blasi F, Oliveira BL, Rietz TA, Rotile NJ, Day H, Looby RJ, Ay I, Caravan P. Effect of Chelate Type and Radioisotope on the Imaging Efficacy of 4 Fibrin-Specific PET Probes. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. 55: 1157-63. PMID 24790217 DOI: 10.2967/Jnumed.113.136275 |
0.34 |
|
| 2014 |
Ay I, Blasi F, Rietz TA, Rotile NJ, Kura S, Brownell AL, Day H, Oliveira BL, Looby RJ, Caravan P. In vivo molecular imaging of thrombosis and thrombolysis using a fibrin-binding positron emission tomographic probe. Circulation. Cardiovascular Imaging. 7: 697-705. PMID 24777937 DOI: 10.1161/Circimaging.113.001806 |
0.341 |
|
| 2014 |
Pierre VC, Allen MJ, Caravan P. Contrast agents for MRI: 30+ years and where are we going? Journal of Biological Inorganic Chemistry : Jbic : a Publication of the Society of Biological Inorganic Chemistry. 19: 127-31. PMID 24414380 DOI: 10.1007/S00775-013-1074-5 |
0.38 |
|
| 2014 |
Andronesi OC, Bhat H, Reuter M, Mukherjee S, Caravan P, Rosen BR. Whole brain mapping of water pools and molecular dynamics with rotating frame MR relaxation using gradient modulated low-power adiabatic pulses. Neuroimage. 89: 92-109. PMID 24345390 DOI: 10.1016/J.Neuroimage.2013.12.007 |
0.344 |
|
| 2014 |
Loving GS, Caravan P. Activation and retention: a magnetic resonance probe for the detection of acute thrombosis. Angewandte Chemie (International Ed. in English). 53: 1140-3. PMID 24338877 DOI: 10.1002/Anie.201308607 |
0.313 |
|
| 2014 |
Boros E, Rybak-Akimova E, Holland JP, Rietz T, Rotile N, Blasi F, Day H, Latifi R, Caravan P. Pycup--a bifunctional, cage-like ligand for (64)Cu radiolabeling. Molecular Pharmaceutics. 11: 617-29. PMID 24294970 DOI: 10.1021/Mp400686Z |
0.728 |
|
| 2014 |
Kolodziej AF, Zhang Z, Overoye-Chan K, Jacques V, Caravan P. Peptide optimization and conjugation strategies in the development of molecularly targeted magnetic resonance imaging contrast agents. Methods in Molecular Biology (Clifton, N.J.). 1088: 185-211. PMID 24146405 DOI: 10.1007/978-1-62703-673-3_13 |
0.333 |
|
| 2013 |
Gale EM, Zhu J, Caravan P. Direct measurement of the Mn(II) hydration state in metal complexes and metalloproteins through 17O NMR line widths. Journal of the American Chemical Society. 135: 18600-8. PMID 24088013 DOI: 10.1021/Ja4094132 |
0.36 |
|
| 2013 |
Caravan P, Yang Y, Zachariah R, Schmitt A, Mino-Kenudson M, Chen HH, Sosnovik DE, Dai G, Fuchs BC, Lanuti M. Molecular magnetic resonance imaging of pulmonary fibrosis in mice. American Journal of Respiratory Cell and Molecular Biology. 49: 1120-6. PMID 23927643 DOI: 10.1165/Rcmb.2013-0039Oc |
0.333 |
|
| 2013 |
Gale EM, Kenton N, Caravan P. [Gd(CyPic3A)(H2O)2]-: a stable, bis(aquated) and high-relaxivity Gd(III) complex. Chemical Communications (Cambridge, England). 49: 8060-2. PMID 23903523 DOI: 10.1039/C3Cc44116D |
0.414 |
|
| 2013 |
Polasek M, Caravan P. Is macrocycle a synonym for kinetic inertness in Gd(III) Complexes? Effect of coordinating and noncoordinating substituents on inertness and relaxivity of Gd(III) chelates with DO3A-like ligands. Inorganic Chemistry. 52: 4084-96. PMID 23517079 DOI: 10.1021/Ic400227K |
0.431 |
|
| 2013 |
Loving GS, Mukherjee S, Caravan P. Redox-activated manganese-based MR contrast agent. Journal of the American Chemical Society. 135: 4620-3. PMID 23510406 DOI: 10.1021/Ja312610J |
0.357 |
|
| 2013 |
Sosnovik DE, Caravan P. Molecular MRI of the Cardiovascular System in the Post-NSF Era. Current Cardiovascular Imaging Reports. 6: 61-68. PMID 23504765 DOI: 10.1007/S12410-012-9182-0 |
0.329 |
|
| 2013 |
Boros E, Caravan P. Structure-relaxivity relationships of serum albumin targeted MRI probes based on a single amino acid Gd complex Journal of Medicinal Chemistry. 56: 1782-1786. PMID 23391162 DOI: 10.1021/Jm4000177 |
0.743 |
|
| 2013 |
Ciesienski KL, Yang Y, Ay I, Chonde DB, Loving GS, Rietz TA, Catana C, Caravan P. Fibrin-targeted PET probes for the detection of thrombi. Molecular Pharmaceutics. 10: 1100-10. PMID 23327109 DOI: 10.1021/Mp300610S |
0.351 |
|
| 2012 |
Boros E, Polasek M, Zhang Z, Caravan P. Gd(DOTAla): A single amino acid Gd-complex as a modular tool for high relaxivity MR contrast agent development Journal of the American Chemical Society. 134: 19858-19868. PMID 23157602 DOI: 10.1021/Ja309187M |
0.743 |
|
| 2012 |
Sosnovik DE, Nahrendorf M, Caravan P. Science to practice: how will myocardial inflammation be imaged with MR imaging? Radiology. 264: 309-11. PMID 22821689 DOI: 10.1148/Radiol.12121094 |
0.343 |
|
| 2012 |
Caravan P, Zhang Z. Structure - relaxivity relationships among targeted MR contrast agents. European Journal of Inorganic Chemistry. 2012: 1916-1923. PMID 22745568 DOI: 10.1002/Ejic.201101364 |
0.441 |
|
| 2012 |
Uppal R, Ciesienski KL, Chonde DB, Loving GS, Caravan P. Discrete bimodal probes for thrombus imaging. Journal of the American Chemical Society. 134: 10799-802. PMID 22698259 DOI: 10.1021/Ja3045635 |
0.365 |
|
| 2012 |
Yang Y, Schühle DT, Dai G, Alford JK, Caravan P. 1H chemical shift magnetic resonance imaging probes with high sensitivity for multiplex imaging. Contrast Media & Molecular Imaging. 7: 276-9. PMID 22434641 DOI: 10.1002/Cmmi.490 |
0.368 |
|
| 2012 |
Moriggi L, Yaseen MA, Helm L, Caravan P. Serum albumin targeted, pH-dependent magnetic resonance relaxation agents. Chemistry (Weinheim An Der Bergstrasse, Germany). 18: 3675-86. PMID 22328098 DOI: 10.1002/Chem.201103344 |
0.348 |
|
| 2011 |
Frullano L, Caravan P. Strategies for the preparation of bifunctional gadolinium(III) chelators. Current Organic Synthesis. 8: 535-565. PMID 22375102 DOI: 10.2174/157017911796117250 |
0.434 |
|
| 2011 |
Zhang Z, Kolodziej AF, Greenfield MT, Caravan P. Heteroditopic binding of magnetic resonance contrast agents for increased relaxivity Angewandte Chemie - International Edition. 50: 2621-2624. PMID 21370351 DOI: 10.1002/Anie.201007689 |
0.324 |
|
| 2011 |
Uppal R, Catana C, Ay I, Benner T, Sorensen AG, Caravan P. Bimodal thrombus imaging: simultaneous PET/MR imaging with a fibrin-targeted dual PET/MR probe--feasibility study in rat model. Radiology. 258: 812-20. PMID 21177389 DOI: 10.1148/Radiol.10100881 |
0.34 |
|
| 2010 |
Ciesienski KL, Caravan P. Molecular MRI of Thrombosis. Current Cardiovascular Imaging Reports. 4: 77-84. PMID 21253438 DOI: 10.1007/S12410-010-9061-5 |
0.366 |
|
| 2010 |
Dumas S, Jacques V, Sun WC, Troughton JS, Welch JT, Chasse JM, Schmitt-Willich H, Caravan P. High relaxivity magnetic resonance imaging contrast agents. Part 1. Impact of single donor atom substitution on relaxivity of serum albumin-bound gadolinium complexes. Investigative Radiology. 45: 600-12. PMID 20808235 DOI: 10.1097/Rli.0B013E3181Ee5A9E |
0.38 |
|
| 2010 |
Jacques V, Dumas S, Sun WC, Troughton JS, Greenfield MT, Caravan P. High-relaxivity magnetic resonance imaging contrast agents part 2: Optimization of inner-and second-sphere relaxivity Investigative Radiology. 45: 613-624. PMID 20808234 DOI: 10.1097/Rli.0B013E3181Ee6A49 |
0.379 |
|
| 2010 |
Uppal R, Caravan P. Targeted probes for cardiovascular MRI. Future Medicinal Chemistry. 2: 451-70. PMID 20539821 DOI: 10.4155/Fmc.09.154 |
0.33 |
|
| 2010 |
Lobbes MB, Heeneman S, Passos VL, Welten R, Kwee RM, van der Geest RJ, Wiethoff AJ, Caravan P, Misselwitz B, Daemen MJ, van Engelshoven JM, Leiner T, Kooi ME. Gadofosveset-enhanced magnetic resonance imaging of human carotid atherosclerotic plaques: a proof-of-concept study. Investigative Radiology. 45: 275-81. PMID 20351652 DOI: 10.1097/Rli.0B013E3181D5466B |
0.338 |
|
| 2010 |
Frullano L, Catana C, Benner T, Sherry AD, Caravan P. Bimodal MR-PET agent for quantitative pH imaging. Angewandte Chemie (International Ed. in English). 49: 2382-4. PMID 20191650 DOI: 10.1002/Anie.201000075 |
0.38 |
|
| 2009 |
Sosnovik DE, Caravan P. Molecular MRI of Atherosclerotic Plaque With Targeted Contrast Agents. Current Cardiovascular Imaging Reports. 2: 87-94. PMID 20019886 DOI: 10.1007/S12410-009-0012-Y |
0.349 |
|
| 2009 |
Aime S, Caravan P. Biodistribution of gadolinium-based contrast agents, including gadolinium deposition. Journal of Magnetic Resonance Imaging : Jmri. 30: 1259-67. PMID 19938038 DOI: 10.1002/Jmri.21969 |
0.314 |
|
| 2009 |
Sherry AD, Caravan P, Lenkinski RE. Primer on gadolinium chemistry. Journal of Magnetic Resonance Imaging : Jmri. 30: 1240-8. PMID 19938036 DOI: 10.1002/Jmri.21966 |
0.411 |
|
| 2009 |
Vymazal J, Spuentrup E, Cardenas-Molina G, Wiethoff AJ, Hartmann MG, Caravan P, Parsons EC. Thrombus imaging with fibrin-specific gadolinium-based MR contrast agent EP-2104R: results of a phase II clinical study of feasibility. Investigative Radiology. 44: 697-704. PMID 19809344 DOI: 10.1097/Rli.0B013E3181B092A7 |
0.368 |
|
| 2009 |
Spuentrup E, Ruhl KM, Botnar RM, Wiethoff AJ, Buhl A, Jacques V, Greenfield MT, Krombach GA, Günther RW, Vangel MG, Caravan P. Molecular magnetic resonance imaging of myocardial perfusion with EP-3600, a collagen-specific contrast agent: initial feasibility study in a swine model. Circulation. 119: 1768-75. PMID 19307474 DOI: 10.1161/Circulationaha.108.826388 |
0.381 |
|
| 2009 |
Caravan P. Protein-targeted gadolinium-based magnetic resonance imaging (MRI) contrast agents: design and mechanism of action. Accounts of Chemical Research. 42: 851-62. PMID 19222207 DOI: 10.1021/Ar800220P |
0.418 |
|
| 2009 |
Caravan P, Farrar CT, Frullano L, Uppal R. Influence of molecular parameters and increasing magnetic field strength on relaxivity of gadolinium- and manganese-based T1 contrast agents. Contrast Media & Molecular Imaging. 4: 89-100. PMID 19177472 DOI: 10.1002/Cmmi.267 |
0.336 |
|
| 2009 |
Caravan P, Das B, Deng Q, Dumas S, Jacques V, Koerner SK, Kolodziej A, Looby RJ, Sun WC, Zhang Z. A lysine walk to high relaxivity collagen-targeted MRI contrast agents. Chemical Communications (Cambridge, England). 430-2. PMID 19137175 DOI: 10.1039/B819098D |
0.359 |
|
| 2008 |
Woods M, Caravan P, Geraldes CF, Greenfield MT, Kiefer GE, Lin M, McMillan K, Prata MI, Santos AC, Sun X, Wang J, Zhang S, Zhao P, Sherry AD. The effect of the amide substituent on the biodistribution and tolerance of lanthanide(III) DOTA-tetraamide derivatives. Investigative Radiology. 43: 861-70. PMID 19002058 DOI: 10.1097/Rli.0B013E318186531D |
0.394 |
|
| 2008 |
Nair SA, Kolodziej AF, Bhole G, Greenfield MT, McMurry TJ, Caravan P. Monovalent and bivalent fibrin-specific MRI contrast agents for detection of thrombus. Angewandte Chemie (International Ed. in English). 47: 4918-21. PMID 18496805 DOI: 10.1002/Anie.200800563 |
0.321 |
|
| 2008 |
Helm PA, Caravan P, French BA, Jacques V, Shen L, Xu Y, Beyers RJ, Roy RJ, Kramer CM, Epstein FH. Postinfarction myocardial scarring in mice: molecular MR imaging with use of a collagen-targeting contrast agent. Radiology. 247: 788-96. PMID 18403626 DOI: 10.1148/Radiol.2473070975 |
0.351 |
|
| 2008 |
Overoye-Chan K, Koerner S, Looby RJ, Kolodziej AF, Zech SG, Deng Q, Chasse JM, McMurry TJ, Caravan P. EP-2104R: a fibrin-specific gadolinium-Based MRI contrast agent for detection of thrombus. Journal of the American Chemical Society. 130: 6025-39. PMID 18393503 DOI: 10.1021/Ja800834Y |
0.333 |
|
| 2008 |
Spuentrup E, Ruhl KM, Botnar RM, Wiethoff AJ, Buhl A, Jacques V, Greenfield MT, Krombach GA, Guenther RW, Caravan P. 207 Molecular MR-Imaging of myocardium using EP-3600, a collagen specific contrast agent: assessment of myocardial perfusion defects in a swine model Journal of Cardiovascular Magnetic Resonance. 10: 1-2. DOI: 10.1186/1532-429X-10-S1-A68 |
0.333 |
|
| 2008 |
Dumas S, Troughton JS, Cloutier NJ, Chasse JM, McMurry TJ, Caravan P. A High Relaxivity Magnetic Resonance Imaging Contrast Agent Targeted to Serum Albumin Australian Journal of Chemistry. 61: 682. DOI: 10.1071/Ch08164 |
0.351 |
|
| 2007 |
Caravan P, Das B, Dumas S, Epstein FH, Helm PA, Jacques V, Koerner S, Kolodziej A, Shen L, Sun WC, Zhang Z. Collagen-targeted MRI contrast agent for molecular imaging of fibrosis. Angewandte Chemie (International Ed. in English). 46: 8171-3. PMID 17893943 DOI: 10.1002/Anie.200700700 |
0.368 |
|
| 2007 |
Caravan P, Parigi G, Chasse JM, Cloutier NJ, Ellison JJ, Lauffer RB, Luchinat C, McDermid SA, Spiller M, McMurry TJ. Albumin binding, relaxivity, and water exchange kinetics of the diastereoisomers of MS-325, a gadolinium(III)-based magnetic resonance angiography contrast agent. Inorganic Chemistry. 46: 6632-9. PMID 17625839 DOI: 10.1021/Ic700686K |
0.369 |
|
| 2007 |
Tyeklar Z, Dunham SU, Midelfort K, Scott DM, Sajiki H, Ong K, Lauffer RB, Caravan P, McMurry TJ. Structural, kinetic, and thermodynamic characterization of the interconverting isomers of MS-325, a gadolinium(III)-based magnetic resonance angiography contrast agent. Inorganic Chemistry. 46: 6621-31. PMID 17625838 DOI: 10.1021/Ic7006843 |
0.389 |
|
| 2007 |
Kalman FK, Woods M, Caravan P, Jurek P, Spiller M, Tircsó G, Kiraly R, Brücher E, Sherry AD. Potentiometric and relaxometric properties of a gadolinium-based MRI contrast agent for sensing tissue pH. Inorganic Chemistry. 46: 5260-70. PMID 17539632 DOI: 10.1021/Ic0702926 |
0.357 |
|
| 2007 |
Zech SG, Eldredge HB, Lowe MP, Caravan P. Protein binding to lanthanide(III) complexes can reduce the water exchange rate at the lanthanide. Inorganic Chemistry. 46: 3576-84. PMID 17425306 DOI: 10.1021/Ic070011U |
0.4 |
|
| 2006 |
Raitsimring AM, Astashkin AV, Baute D, Goldfarb D, Poluektov OG, Lowe MP, Zech SG, Caravan P. Determination of the hydration number of gadolinium(III) complexes by high-field pulsed 17O ENDOR spectroscopy. Chemphyschem : a European Journal of Chemical Physics and Physical Chemistry. 7: 1590-7. PMID 16810729 DOI: 10.1002/Cphc.200600138 |
0.388 |
|
| 2006 |
Caravan P. Strategies for increasing the sensitivity of gadolinium based MRI contrast agents. Chemical Society Reviews. 35: 512-23. PMID 16729145 DOI: 10.1039/B510982P |
0.407 |
|
| 2005 |
Zech SG, Sun WC, Jacques V, Caravan P, Astashkin AV, Raitsimring AM. Probing the water coordination of protein-targeted MRI contrast agents by pulsed ENDOR spectroscopy. Chemphyschem : a European Journal of Chemical Physics and Physical Chemistry. 6: 2570-7. PMID 16294353 DOI: 10.1002/Cphc.200500250 |
0.42 |
|
| 2005 |
Zhang Z, Greenfield MT, Spiller M, McMurry TJ, Lauffer RB, Caravan P. Multilocus binding increases the relaxivity of protein-bound MRI contrast agents. Angewandte Chemie (International Ed. in English). 44: 6766-9. PMID 16173108 DOI: 10.1002/Anie.200502245 |
0.321 |
|
| 2005 |
Caravan P, Amedio JC, Dunham SU, Greenfield MT, Cloutier NJ, McDermid SA, Spiller M, Zech SG, Looby RJ, Raitsimring AM, McMurry TJ, Lauffer RB. When are two waters worse than one? Doubling the hydration number of a Gd-DTPA derivative decreases relaxivity. Chemistry (Weinheim An Der Bergstrasse, Germany). 11: 5866-74. PMID 16052656 DOI: 10.1002/Chem.200500338 |
0.377 |
|
| 2005 |
Raitsimring AM, Astashkin AV, Poluektov OG, Caravan P. High-field pulsed EPR and ENDOR of Gd3+ complexes in glassy solutions Applied Magnetic Resonance. 28: 281-295. DOI: 10.1007/Bf03166762 |
0.301 |
|
| 2004 |
Troughton JS, Greenfield MT, Greenwood JM, Dumas S, Wiethoff AJ, Wang J, Spiller M, McMurry TJ, Caravan P. Synthesis and evaluation of a high relaxivity manganese(II)-based MRI contrast agent. Inorganic Chemistry. 43: 6313-23. PMID 15446878 DOI: 10.1021/Ic049559G |
0.406 |
|
| 2004 |
Zhou X, Caravan P, Clarkson RB, Westlund PO. On the philosophy of optimizing contrast agents. An analysis of 1H NMRD profiles and ESR lineshapes of the Gd(III)complex MS-325+HSA. Journal of Magnetic Resonance (San Diego, Calif. : 1997). 167: 147-60. PMID 14987609 DOI: 10.1016/J.Jmr.2003.12.006 |
0.312 |
|
| 2004 |
Raitsimring AM, Astashkin AV, Baute D, Goldfarb D, Caravan P. W-band 17O pulsed electron nuclear double resonance study of gadolinium complexes with water Journal of Physical Chemistry A. 108: 7318-7323. DOI: 10.1021/Jp040306I |
0.349 |
|
| 2003 |
Caravan P, Astashkin AV, Raitsimring AM. The gadolinium(III)-water hydrogen distance in MRI contrast agents. Inorganic Chemistry. 42: 3972-4. PMID 12817950 DOI: 10.1021/Ic034414F |
0.356 |
|
| 2001 |
Nivorozhkin AL, Kolodziej AF, Caravan P, Greenfield MT, Lauffer RB, McMurry TJ. Enzyme-Activated Gd Magnetic Resonance Imaging Contrast Agents with a Prominent Receptor-Induced Magnetization Enhancement. Angewandte Chemie (International Ed. in English). 40: 2903-2906. PMID 29711998 DOI: 10.1002/1521-3773(20010803)40:15<2903::Aid-Anie2903>3.0.Co;2-N |
0.389 |
|
| 2001 |
Caravan P, Greenfield MT, Li X, Sherry AD. The Gd(3+) complex of a fatty acid analogue of DOTP binds to multiple albumin sites with variable water relaxivities. Inorganic Chemistry. 40: 6580-7. PMID 11735466 DOI: 10.1021/Ic0102900 |
0.354 |
|
| 2001 |
Caravan P, Greenfield MT, Bulte JW. Molecular factors that determine Curie spin relaxation in dysprosium complexes. Magnetic Resonance in Medicine. 46: 917-22. PMID 11675643 DOI: 10.1002/Mrm.1277 |
0.344 |
|
| 2001 |
Caravan P, Comuzzi C, Crooks W, McMurry TJ, Choppin GR, Woulfe SR. Thermodynamic stability and kinetic inertness of MS-325, a new blood pool agent for magnetic resonance imaging. Inorganic Chemistry. 40: 2170-6. PMID 11304163 DOI: 10.1021/Ic001117R |
0.365 |
|
| 1999 |
Caravan P, Ellison JJ, McMurry TJ, Lauffer RB. Gadolinium(III) Chelates as MRI Contrast Agents: Structure, Dynamics, and Applications. Chemical Reviews. 99: 2293-352. PMID 11749483 DOI: 10.1021/Cr980440X |
0.307 |
|
| 1998 |
Lowe MP, Caravan P, Rettig SJ, Orvig C. Tightening the Hydrophobic Belt: Effects of Backbone and Donor Group Variation on Podand Ligand Complexes of the Lanthanides Inorganic Chemistry. 37: 1637-1647. DOI: 10.1021/Ic971488G |
0.651 |
|
| 1997 |
Caravan P, Mehrkhodavandi P, Orvig C. Cationic Lanthanide Complexes of N,N'-Bis(2-pyridylmethyl)ethylenediamine-N,N'-diacetic Acid (H(2)bped). Inorganic Chemistry. 36: 1316-1321. PMID 11669707 DOI: 10.1021/Ic9613016 |
0.649 |
|
| 1997 |
Caravan P, Rettig SJ, Orvig C. Effect of Pyridyl Donors in the Chelation of Aluminum(III), Gallium(III), and Indium(III). Inorganic Chemistry. 36: 1306-1315. PMID 11669706 DOI: 10.1021/Ic961230A |
0.654 |
|
| 1997 |
Yuen VG, Caravan P, Gelmini L, Glover N, McNeill JH, Setyawati IA, Zhou Y, Orvig C. Glucose-lowering properties of vanadium compounds: comparison of coordination complexes with maltol or kojic acid as ligands. Journal of Inorganic Biochemistry. 68: 109-16. PMID 9336969 DOI: 10.1016/S0162-0134(97)00082-2 |
0.633 |
|
| 1997 |
Caravan P, Orvig C. Tripodal Aminophenolate Ligand Complexes of Aluminum(III), Gallium(III), and Indium(III) in Water Inorganic Chemistry. 36: 236-248. DOI: 10.1021/Ic961222U |
0.623 |
|
| 1997 |
Caravan P, Lowe MP, Read PW, Rettig SJ, Yang LW, Orvig C. Selectivity among, and aggregation of, lanthanide ions Journal of Alloys and Compounds. 249: 49-51. DOI: 10.1016/S0925-8388(96)02641-2 |
0.645 |
|
| 1996 |
Wong E, Caravan P, Liu S, Rettig SJ, Orvig C. Selectivity of Potentially Hexadentate Amine Phenols for Ga3+ and In3+ in Aqueous Solution Inorganic Chemistry. 35: 715-724. DOI: 10.1021/Ic951019J |
0.622 |
|
| 1995 |
Caravan P, Gelmini L, Glover N, Geoffrey Herring F, Li H, McNeill JH, Rettig SJ, Setyawati IA, Shuter E, Sun Y, Tracey AS, Yuen VG, Orvig C. Reaction chemistry of BMOV, bis(maltolato)oxovanadium(IV) - A potent insulin mimetic agent Journal of the American Chemical Society. 117: 12759-12770. DOI: 10.1021/Ja00156A013 |
0.599 |
|
| 1995 |
Caravan P, Hedlund T, Liu S, Sjöberg S, Orvig C. Potentiometric, calorimetric, and solution NMR studies of a tridentate ligand which has a marked preference for formation of bis(ligand) versus mono(ligand) lanthanide complexes and which exhibits high selectivity for heavier lanthanides Journal of the American Chemical Society. 117: 11230-11238. DOI: 10.1021/Ja00150A021 |
0.646 |
|
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