Roger A Pedersen, PhD - Publications

Affiliations: 
1971-2001 University of California, San Francisco, San Francisco, CA 
 2001- University of Cambridge, Cambridge, England, United Kingdom 
Area:
Regenerative Medicine, embryonic stem cells
Website:
https://selectbiosciences.com/conferences/biographies.aspx?speaker=219225&conf=scdd2017

150 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Zawada D, Kornherr J, Meier AB, Santamaria G, Dorn T, Nowak-Imialek M, Ortmann D, Zhang F, Lachmann M, Dreßen M, Ortiz M, Mascetti VL, Harmer SC, Nobles M, Tinker A, ... ... Pedersen RA, et al. Retinoic acid signaling modulation guides in vitro specification of human heart field-specific progenitor pools. Nature Communications. 14: 1722. PMID 37012244 DOI: 10.1038/s41467-023-36764-x  0.309
2021 Hyun I, Clayton EW, Cong Y, Fujita M, Goldman SA, Hill LR, Monserrat N, Nakauchi H, Pedersen RA, Rooke HM, Takahashi J, Knoblich JA. ISSCR guidelines for the transfer of human pluripotent stem cells and their direct derivatives into animal hosts. Stem Cell Reports. PMID 34048695 DOI: 10.1016/j.stemcr.2021.05.005  0.316
2019 Dirks RAM, van Mierlo G, Kerstens HHD, Bernardo AS, Kobolák J, Bock I, Maruotti J, Pedersen RA, Dinnyés A, Huynen MA, Jouneau A, Marks H. Allele-specific RNA-seq expression profiling of imprinted genes in mouse isogenic pluripotent states. Epigenetics & Chromatin. 12: 14. PMID 30767785 DOI: 10.1186/S13072-019-0259-8  0.473
2018 Bernardo AS, Jouneau A, Marks H, Kensche P, Kobolak J, Freude K, Hall V, Feher A, Polgar Z, Sartori C, Bock I, Louet C, Faial T, Kerstens HHD, Bouissou C, ... ... Pedersen RA, et al. Mammalian embryo comparison identifies novel pluripotency genes associated with the naïve or primed state. Biology Open. PMID 30026265 DOI: 10.1242/Bio.033282  0.453
2018 Xing Y, Zhao S, Wei Q, Gong S, Zhao X, Zhou F, Ai-Lamki R, Ortmann D, Du M, Pedersen R, Shang G, Si S, Morrell NW, Yang J. A novel piperidine identified by stem cell based screening attenuates pulmonary arterial hypertensionregulating BMP2 and PTGS2 levels. The European Respiratory Journal. PMID 29449428 DOI: 10.1183/13993003.02229-2017  0.379
2017 Moreau T, Evans AL, Vasquez L, Tijssen MR, Yan Y, Trotter MW, Howard D, Colzani M, Arumugam M, Wu WH, Dalby A, Lampela R, Bouet G, Hobbs CM, Pask DC, ... ... Pedersen RA, et al. Corrigendum: Large-scale production of megakaryocytes from human pluripotent stem cells by chemically defined forward programming. Nature Communications. 8: 15076. PMID 28752836 DOI: 10.1038/Ncomms15076  0.357
2017 Pawlowski M, Ortmann D, Bertero A, Tavares JM, Pedersen RA, Vallier L, Kotter MR. Inducible and Deterministic Forward Programming of Human Pluripotent Stem Cells into Neurons, Skeletal Myocytes, and Oligodendrocytes. Stem Cell Reports. PMID 28344001 DOI: 10.1016/J.Stemcr.2017.02.016  0.42
2017 Juan AH, Wang S, Ko KD, Zare H, Tsai PF, Feng X, Vivanco KO, Ascoli AM, Gutierrez-Cruz G, Krebs J, Sidoli S, Knight AL, Pedersen RA, Garcia BA, Casellas R, et al. Roles of H3K27me2 and H3K27me3 Examined during Fate Specification of Embryonic Stem Cells. Cell Reports. 18: 297. PMID 28052258 DOI: 10.1016/j.celrep.2016.12.036  0.376
2016 Juan AH, Wang S, Ko KD, Zare H, Tsai PF, Feng X, Vivanco KO, Ascoli AM, Gutierrez-Cruz G, Krebs J, Sidoli S, Knight AL, Pedersen RA, Garcia BA, Casellas R, et al. Roles of H3K27me2 and H3K27me3 Examined during Fate Specification of Embryonic Stem Cells. Cell Reports. 17: 1369-1382. PMID 27783950 DOI: 10.1016/J.Celrep.2016.09.087  0.418
2016 Mascetti VL, Pedersen RA. Contributions of Mammalian Chimeras to Pluripotent Stem Cell Research. Cell Stem Cell. 19: 163-75. PMID 27494674 DOI: 10.1016/J.Stem.2016.07.018  0.451
2016 Moreau T, Evans AL, Vasquez L, Tijssen MR, Yan Y, Trotter MW, Howard D, Colzani M, Arumugam M, Wu WH, Dalby A, Lampela R, Bouet G, Hobbs CM, Pask DC, ... ... Pedersen RA, et al. Large-scale production of megakaryocytes from human pluripotent stem cells by chemically defined forward programming. Nature Communications. 7: 11208. PMID 27052461 DOI: 10.1038/Ncomms11208  0.375
2016 Iyer D, Gambardella L, Bernard WG, Serrano F, Mascetti VL, Pedersen RA, Sinha S, Talasila A. Robust derivation of epicardium and its differentiated smooth muscle cell progeny from human pluripotent stem cells. Development (Cambridge, England). 143: 904. PMID 26932673 DOI: 10.1242/dev.136143  0.335
2015 Mascetti VL, Pedersen RA. Human-Mouse Chimerism Validates Human Stem Cell Pluripotency. Cell Stem Cell. PMID 26712580 DOI: 10.1016/J.Stem.2015.11.017  0.499
2015 Bertacchi M, Lupo G, Pandolfini L, Casarosa S, D'Onofrio M, Pedersen RA, Harris WA, Cremisi F. Activin/Nodal Signaling Supports Retinal Progenitor Specification in a Narrow Time Window during Pluripotent Stem Cell Neuralization. Stem Cell Reports. 5: 532-45. PMID 26388287 DOI: 10.1016/J.Stemcr.2015.08.011  0.364
2015 Strogantsev R, Krueger F, Yamazawa K, Shi H, Gould P, Goldman-Roberts M, McEwen K, Sun B, Pedersen R, Ferguson-Smith AC. Allele-specific binding of ZFP57 in the epigenetic regulation of imprinted and non-imprinted monoallelic expression. Genome Biology. 16: 112. PMID 26025256 DOI: 10.1186/S13059-015-0672-7  0.417
2015 Faial T, Bernardo AS, Mendjan S, Diamanti E, Ortmann D, Gentsch GE, Mascetti VL, Trotter MW, Smith JC, Pedersen RA. Brachyury and SMAD signalling collaboratively orchestrate distinct mesoderm and endoderm gene regulatory networks in differentiating human embryonic stem cells. Development (Cambridge, England). 142: 2121-35. PMID 26015544 DOI: 10.1242/Dev.117838  0.499
2015 Iyer D, Gambardella L, Bernard WG, Serrano F, Mascetti VL, Pedersen RA, Talasila A, Sinha S. Robust derivation of epicardium and its differentiated smooth muscle cell progeny from human pluripotent stem cells. Development (Cambridge, England). 142: 1528-41. PMID 25813541 DOI: 10.1242/Dev.119271  0.467
2015 Bertero A, Madrigal P, Galli A, Hubner NC, Moreno I, Burks D, Brown S, Pedersen RA, Gaffney D, Mendjan S, Pauklin S, Vallier L. Activin/nodal signaling and NANOG orchestrate human embryonic stem cell fate decisions by controlling the H3K4me3 chromatin mark. Genes & Development. 29: 702-17. PMID 25805847 DOI: 10.1101/Gad.255984.114  0.473
2015 Soares FA, Pedersen RA, Vallier L. Generation of Human Induced Pluripotent Stem Cells from Peripheral Blood Mononuclear Cells Using Sendai Virus. Methods in Molecular Biology (Clifton, N.J.). PMID 25687300 DOI: 10.1007/7651_2015_202  0.438
2014 Morioka T, Sakabe M, Ioka T, Iguchi T, Mizuta K, Hattammaru M, Sakai C, Itoh M, Sato GE, Hashimoto A, Fujita M, Okumura K, Araki M, Xin M, Pedersen RA, et al. An important role of endothelial hairy-related transcription factors in mouse vascular development. Genesis (New York, N.Y. : 2000). 52: 897-906. PMID 25264302 DOI: 10.1002/Dvg.22825  0.318
2014 Mendjan S, Mascetti VL, Ortmann D, Ortiz M, Karjosukarso DW, Ng Y, Moreau T, Pedersen RA. NANOG and CDX2 pattern distinct subtypes of human mesoderm during exit from pluripotency. Cell Stem Cell. 15: 310-25. PMID 25042702 DOI: 10.1016/J.Stem.2014.06.006  0.406
2014 Veillard AC, Marks H, Bernardo AS, Jouneau L, Laloë D, Boulanger L, Kaan A, Brochard V, Tosolini M, Pedersen R, Stunnenberg H, Jouneau A. Stable methylation at promoters distinguishes epiblast stem cells from embryonic stem cells and the in vivo epiblasts. Stem Cells and Development. 23: 2014-29. PMID 24738887 DOI: 10.1089/Scd.2013.0639  0.419
2014 Cheung C, Bernardo AS, Pedersen RA, Sinha S. Directed differentiation of embryonic origin-specific vascular smooth muscle subtypes from human pluripotent stem cells. Nature Protocols. 9: 929-38. PMID 24675733 DOI: 10.1038/Nprot.2014.059  0.413
2014 Roberts RM, Loh KM, Amita M, Bernardo AS, Adachi K, Alexenko AP, Schust DJ, Schulz LC, Telugu BP, Ezashi T, Pedersen RA. Differentiation of trophoblast cells from human embryonic stem cells: to be or not to be? Reproduction (Cambridge, England). 147: D1-12. PMID 24518070 DOI: 10.1530/Rep-14-0080  0.489
2014 Soares FA, Chandra A, Thomas RJ, Pedersen RA, Vallier L, Williams DJ. Investigating the feasibility of scale up and automation of human induced pluripotent stem cells cultured in aggregates in feeder free conditions. Journal of Biotechnology. 173: 53-8. PMID 24440272 DOI: 10.1016/J.Jbiotec.2013.12.009  0.444
2014 Mascetti VL, Pedersen RA. Naiveté of the human pluripotent stem cell. Nature Biotechnology. 32: 68-70. PMID 24406934 DOI: 10.1038/Nbt.2789  0.455
2013 Fordham RP, Yui S, Hannan NR, Soendergaard C, Madgwick A, Schweiger PJ, Nielsen OH, Vallier L, Pedersen RA, Nakamura T, Watanabe M, Jensen KB. Transplantation of expanded fetal intestinal progenitors contributes to colon regeneration after injury. Cell Stem Cell. 13: 734-44. PMID 24139758 DOI: 10.1016/J.Stem.2013.09.015  0.432
2013 Lupo G, Novorol C, Smith JR, Vallier L, Miranda E, Alexander M, Biagioni S, Pedersen RA, Harris WA. Multiple roles of Activin/Nodal, bone morphogenetic protein, fibroblast growth factor and Wnt/β-catenin signalling in the anterior neural patterning of adherent human embryonic stem cell cultures. Open Biology. 3: 120167. PMID 23576785 DOI: 10.1098/Rsob.120167  0.407
2013 Moreau T, Colzani M, Arumugam M, Evans A, Renee Tijssen M, Trotter M, Ouwehand WH, Pedersen R, Ghevaert C. In Vitro Production Of Megakaryocytes and Platelets From Human Induced Pluripotent Cells By GMP Compatible Methods Blood. 122: 2401-2401. DOI: 10.1182/Blood.V122.21.2401.2401  0.448
2012 Cho LT, Wamaitha SE, Tsai IJ, Artus J, Sherwood RI, Pedersen RA, Hadjantonakis AK, Niakan KK. Conversion from mouse embryonic to extra-embryonic endoderm stem cells reveals distinct differentiation capacities of pluripotent stem cell states. Development (Cambridge, England). 139: 2866-77. PMID 22791892 DOI: 10.1242/Dev.078519  0.537
2012 Pedersen RA, Mascetti V, Mendjan S. Synthetic organs for regenerative medicine. Cell Stem Cell. 10: 646-7. PMID 22704499 DOI: 10.1016/J.Stem.2012.04.003  0.339
2012 Evans AL, Faial T, Gilchrist MJ, Down T, Vallier L, Pedersen RA, Wardle FC, Smith JC. Genomic targets of Brachyury (T) in differentiating mouse embryonic stem cells. Plos One. 7: e33346. PMID 22479388 DOI: 10.1371/Journal.Pone.0033346  0.358
2012 Yang VS, Carter SA, Ng Y, Hyland SJ, Tachibana-Konwalski K, Fisher RA, Sebire NJ, Seckl MJ, Pedersen RA, Laskey RA, Gonzalez MA. Distinct activities of the anaphase-promoting complex/cyclosome (APC/C) in mouse embryonic cells. Cell Cycle (Georgetown, Tex.). 11: 846-55. PMID 22333576 DOI: 10.4161/Cc.11.5.19251  0.459
2012 Niakan KK, Han J, Pedersen RA, Simon C, Pera RA. Human pre-implantation embryo development. Development (Cambridge, England). 139: 829-41. PMID 22318624 DOI: 10.1242/Dev.060426  0.384
2012 Cheung C, Bernardo AS, Trotter MW, Pedersen RA, Sinha S. Generation of human vascular smooth muscle subtypes provides insight into embryological origin-dependent disease susceptibility. Nature Biotechnology. 30: 165-73. PMID 22252507 DOI: 10.1038/Nbt.2107  0.324
2012 Sun B, Ito M, Mendjan S, Ito Y, Brons IG, Murrell A, Vallier L, Ferguson-Smith AC, Pedersen RA. Status of genomic imprinting in epigenetically distinct pluripotent stem cells. Stem Cells (Dayton, Ohio). 30: 161-8. PMID 22109880 DOI: 10.1002/Stem.793  0.501
2012 Gupta K, Patani R, Baxter P, Serio A, Story D, Tsujita T, Hayes JD, Pedersen RA, Hardingham GE, Chandran S. Human embryonic stem cell derived astrocytes mediate non-cell-autonomous neuroprotection through endogenous and drug-induced mechanisms. Cell Death and Differentiation. 19: 779-87. PMID 22095276 DOI: 10.1038/Cdd.2011.154  0.382
2012 Pedersen R. Mechanisms of Mesoderm Differentiation in Pluripotent Mammalian Stem Cells Qscience Proceedings. 2012: 6. DOI: 10.5339/qproc.2012.stem.1.6  0.351
2011 Pauklin S, Pedersen RA, Vallier L. Mouse pluripotent stem cells at a glance. Journal of Cell Science. 124: 3727-32. PMID 22124139 DOI: 10.1242/Jcs.074120  0.51
2011 Bernardo AS, Faial T, Gardner L, Niakan KK, Ortmann D, Senner CE, Callery EM, Trotter MW, Hemberger M, Smith JC, Bardwell L, Moffett A, Pedersen RA. BRACHYURY and CDX2 mediate BMP-induced differentiation of human and mouse pluripotent stem cells into embryonic and extraembryonic lineages. Cell Stem Cell. 9: 144-55. PMID 21816365 DOI: 10.1016/J.Stem.2011.06.015  0.527
2011 Brown S, Teo A, Pauklin S, Hannan N, Cho CH, Lim B, Vardy L, Dunn NR, Trotter M, Pedersen R, Vallier L. Activin/Nodal signaling controls divergent transcriptional networks in human embryonic stem cells and in endoderm progenitors. Stem Cells (Dayton, Ohio). 29: 1176-85. PMID 21630377 DOI: 10.1002/Stem.666  0.402
2011 Patani R, Hollins AJ, Wishart TM, Puddifoot CA, Alvarez S, de Lera AR, Wyllie DJ, Compston DA, Pedersen RA, Gillingwater TH, Hardingham GE, Allen ND, Chandran S. Retinoid-independent motor neurogenesis from human embryonic stem cells reveals a medial columnar ground state. Nature Communications. 2: 214. PMID 21364553 DOI: 10.1038/Ncomms1216  0.354
2011 Chng Z, Vallier L, Pedersen R. Activin/nodal signaling and pluripotency. Vitamins and Hormones. 85: 39-58. PMID 21353875 DOI: 10.1016/B978-0-12-385961-7.00003-2  0.497
2011 Mascetti V, Mendjan S, Bernardo AS, Ortmann D, Pedersen RA. 58 Wnt/ -Catenin Signalling At The Heart Of Cardiogenic Mesoderm Specification Heart. 97: e7-e7. DOI: 10.1136/Heartjnl-2011-300920B.58  0.406
2011 Cheung C, Bernardo A, Trotter M, Pedersen RA, Sinha S. 11 Generation of developmental origin-specific vascular smooth muscle cells from human embryonic stem cells Heart. 97: e7-e7. DOI: 10.1136/Heartjnl-2011-300920B.11  0.455
2010 Hemberger M, Pedersen R. Stem cells. Epigenome disruptors. Science (New York, N.Y.). 330: 598-9. PMID 21030637 DOI: 10.1126/Science.1199006  0.435
2010 Touboul T, Hannan NR, Corbineau S, Martinez A, Martinet C, Branchereau S, Mainot S, Strick-Marchand H, Pedersen R, Di Santo J, Weber A, Vallier L. Generation of functional hepatocytes from human embryonic stem cells under chemically defined conditions that recapitulate liver development. Hepatology (Baltimore, Md.). 51: 1754-65. PMID 20301097 DOI: 10.1002/Hep.23506  0.473
2010 Maruotti J, Dai XP, Brochard V, Jouneau L, Liu J, Bonnet-Garnier A, Jammes H, Vallier L, Brons IG, Pedersen R, Renard JP, Zhou Q, Jouneau A. Nuclear transfer-derived epiblast stem cells are transcriptionally and epigenetically distinguishable from their fertilized-derived counterparts. Stem Cells (Dayton, Ohio). 28: 743-52. PMID 20201062 DOI: 10.1002/Stem.400  0.522
2010 Chng Z, Teo A, Pedersen RA, Vallier L. SIP1 mediates cell-fate decisions between neuroectoderm and mesendoderm in human pluripotent stem cells. Cell Stem Cell. 6: 59-70. PMID 20074535 DOI: 10.1016/J.Stem.2009.11.015  0.468
2009 Vallier L, Touboul T, Brown S, Cho C, Bilican B, Alexander M, Cedervall J, Chandran S, Ahrlund-Richter L, Weber A, Pedersen RA. Signaling pathways controlling pluripotency and early cell fate decisions of human induced pluripotent stem cells. Stem Cells (Dayton, Ohio). 27: 2655-66. PMID 19688839 DOI: 10.1002/Stem.199  0.499
2009 Vallier L, Touboul T, Chng Z, Brimpari M, Hannan N, Millan E, Smithers LE, Trotter M, Rugg-Gunn P, Weber A, Pedersen RA. Early cell fate decisions of human embryonic stem cells and mouse epiblast stem cells are controlled by the same signalling pathways. Plos One. 4: e6082. PMID 19564924 DOI: 10.1371/Journal.Pone.0006082  0.529
2009 Pedersen R. Out with the old, in with the new? Science (New York, N.Y.). 324: 1617. PMID 19556472 DOI: 10.1126/Science.1177267  0.394
2009 Vallier L, Mendjan S, Brown S, Chng Z, Teo A, Smithers LE, Trotter MW, Cho CH, Martinez A, Rugg-Gunn P, Brons G, Pedersen RA. Activin/Nodal signalling maintains pluripotency by controlling Nanog expression. Development (Cambridge, England). 136: 1339-49. PMID 19279133 DOI: 10.1242/Dev.033951  0.495
2009 Bernardo AS, Cho CH, Mason S, Docherty HM, Pedersen RA, Vallier L, Docherty K. Biphasic induction of Pdx1 in mouse and human embryonic stem cells can mimic development of pancreatic beta-cells. Stem Cells (Dayton, Ohio). 27: 341-51. PMID 19056911 DOI: 10.1634/Stemcells.2008-0310  0.499
2008 Vallier L, Pedersen R. Differentiation of human embryonic stem cells in adherent and in chemically defined culture conditions. Current Protocols in Stem Cell Biology. Unit 1D.4.1-1D.4.7. PMID 18770639 DOI: 10.1002/9780470151808.Sc01D04S4  0.486
2008 Smith JR, Maguire S, Davis LA, Alexander M, Yang F, Chandran S, ffrench-Constant C, Pedersen RA. Robust, persistent transgene expression in human embryonic stem cells is achieved with AAVS1-targeted integration. Stem Cells (Dayton, Ohio). 26: 496-504. PMID 18024421 DOI: 10.1634/Stemcells.2007-0039  0.405
2008 Smith JR, Vallier L, Lupo G, Alexander M, Harris WA, Pedersen RA. Inhibition of Activin/Nodal signaling promotes specification of human embryonic stem cells into neuroectoderm. Developmental Biology. 313: 107-17. PMID 18022151 DOI: 10.1016/J.Ydbio.2007.10.003  0.463
2007 Kim K, Ng K, Rugg-Gunn PJ, Shieh JH, Kirak O, Jaenisch R, Wakayama T, Moore MA, Pedersen RA, Daley GQ. Recombination signatures distinguish embryonic stem cells derived by parthenogenesis and somatic cell nuclear transfer. Cell Stem Cell. 1: 346-52. PMID 18371368 DOI: 10.1016/J.Stem.2007.07.001  0.436
2007 Rugg-Gunn PJ, Ferguson-Smith AC, Pedersen RA. Status of genomic imprinting in human embryonic stem cells as revealed by a large cohort of independently derived and maintained lines. Human Molecular Genetics. 16: R243-51. PMID 17911167 DOI: 10.1093/Hmg/Ddm245  0.47
2007 Soh BS, Song CM, Vallier L, Li P, Choong C, Yeo BH, Lim EH, Pedersen RA, Yang HH, Rao M, Lim B. Pleiotrophin enhances clonal growth and long-term expansion of human embryonic stem cells. Stem Cells (Dayton, Ohio). 25: 3029-37. PMID 17823238 DOI: 10.1634/Stemcells.2007-0372  0.467
2007 Brons IG, Smithers LE, Trotter MW, Rugg-Gunn P, Sun B, Chuva de Sousa Lopes SM, Howlett SK, Clarkson A, Ahrlund-Richter L, Pedersen RA, Vallier L. Derivation of pluripotent epiblast stem cells from mammalian embryos. Nature. 448: 191-5. PMID 17597762 DOI: 10.1038/Nature05950  0.525
2007 Adewumi O, Aflatoonian B, Ahrlund-Richter L, Amit M, Andrews PW, Beighton G, Bello PA, Benvenisty N, Berry LS, Bevan S, Blum B, Brooking J, Chen KG, Choo AB, ... ... Pedersen R, et al. Characterization of human embryonic stem cell lines by the International Stem Cell Initiative. Nature Biotechnology. 25: 803-16. PMID 17572666 DOI: 10.1038/Nbt1318  0.452
2007 Vallier L, Alexander M, Pedersen R. Conditional gene expression in human embryonic stem cells. Stem Cells (Dayton, Ohio). 25: 1490-7. PMID 17322103 DOI: 10.1634/Stemcells.2006-0825  0.483
2006 Bowles KM, Vallier L, Smith JR, Alexander MR, Pedersen RA. HOXB4 overexpression promotes hematopoietic development by human embryonic stem cells. Stem Cells (Dayton, Ohio). 24: 1359-69. PMID 16410392 DOI: 10.1634/Stemcells.2005-0210  0.521
2005 Vallier L, Pedersen RA. Human embryonic stem cells: an in vitro model to study mechanisms controlling pluripotency in early mammalian development. Stem Cell Reviews. 1: 119-30. PMID 17142846 DOI: 10.1385/Scr:1:2:119  0.538
2005 Lavoir MC, Weier J, Conaghan J, Pedersen RA. Poor development of human nuclear transfer embryos using failed fertilized oocytes. Reproductive Biomedicine Online. 11: 740-4. PMID 16417739 DOI: 10.1016/S1472-6483(10)61693-8  0.412
2005 Taylor CJ, Bolton EM, Pocock S, Sharples LD, Pedersen RA, Bradley JA. Banking on human embryonic stem cells: estimating the number of donor cell lines needed for HLA matching. Lancet (London, England). 366: 2019-25. PMID 16338451 DOI: 10.1016/S0140-6736(05)67813-0  0.411
2005 Rugg-Gunn PJ, Ferguson-Smith AC, Pedersen RA. Human embryonic stem cells as a model for studying epigenetic regulation during early development. Cell Cycle (Georgetown, Tex.). 4: 1323-6. PMID 16205114 DOI: 10.4161/Cc.4.10.2076  0.478
2005 Vallier L, Alexander M, Pedersen RA. Activin/Nodal and FGF pathways cooperate to maintain pluripotency of human embryonic stem cells. Journal of Cell Science. 118: 4495-509. PMID 16179608 DOI: 10.1242/Jcs.02553  0.492
2005 Schatten G, Smith J, Navara C, Park JH, Pedersen R. Culture of human embryonic stem cells. Nature Methods. 2: 455-63. PMID 16170868 DOI: 10.1038/Nmeth0605-455  0.495
2005 Pfendler KC, Catuar CS, Meneses JJ, Pedersen RA. Overexpression of Nodal promotes differentiation of mouse embryonic stem cells into mesoderm and endoderm at the expense of neuroectoderm formation. Stem Cells and Development. 14: 162-72. PMID 15910242 DOI: 10.1089/Scd.2005.14.162  0.484
2005 Rugg-Gunn PJ, Ferguson-Smith AC, Pedersen RA. Epigenetic status of human embryonic stem cells. Nature Genetics. 37: 585-7. PMID 15864307 DOI: 10.1038/Ng1556  0.455
2005 McMahan J, Cohen J, Ko M, Johnson M, Robertson J, Murphy T, Brinsden P, Hussein F, Savulescu J, McLaren A, McLean S, Harris J, Schulman J, Edwards R, Pedersen R, et al. Discussion (day 2 session 2): Modern genetics and the human embryo in vitro. Reproductive Biomedicine Online. 10: 107-10. PMID 15820019 DOI: 10.1016/S1472-6483(10)62216-X  0.321
2005 Lockwood M, McLaren A, Pedersen R, Holm S, Bortolotti L, Savulescu J, Brinsden P, Edwards R, Short R, Robertson J, Lotz M, Ogilvie C, Lockwood G, Onland J, Leather S. Discussion (day 2 session 1): Stem cell outlook. Reproductive Biomedicine Online. 10: 76-9. PMID 15820014 DOI: 10.1016/S1472-6483(10)62211-0  0.366
2005 Pedersen RA. Developments in human embryonic stem cells. Reproductive Biomedicine Online. 10: 60-2. PMID 15820011 DOI: 10.1016/S1472-6483(10)62208-0  0.469
2004 Vallier L, Reynolds D, Pedersen RA. Nodal inhibits differentiation of human embryonic stem cells along the neuroectodermal default pathway. Developmental Biology. 275: 403-21. PMID 15501227 DOI: 10.1016/J.Ydbio.2004.08.031  0.517
2004 Stoffel M, Vallier L, Pedersen RA. Navigating the pathway from embryonic stem cells to beta cells. Seminars in Cell & Developmental Biology. 15: 327-36. PMID 15125896 DOI: 10.1016/J.Semcdb.2004.02.002  0.442
2004 Kawase E, Hashimoto K, Pedersen RA. Autocrine and paracrine mechanisms regulating primordial germ cell proliferation. Molecular Reproduction and Development. 68: 5-16. PMID 15039943 DOI: 10.1002/Mrd.20031  0.406
2004 Vallier L, Rugg-Gunn PJ, Bouhon IA, Andersson FK, Sadler AJ, Pedersen RA. Enhancing and diminishing gene function in human embryonic stem cells. Stem Cells (Dayton, Ohio). 22: 2-11. PMID 14688386 DOI: 10.1634/Stemcells.22-1-2  0.445
2002 Bradley JA, Bolton EM, Pedersen RA. Stem cell medicine encounters the immune system. Nature Reviews. Immunology. 2: 859-71. PMID 12415309 DOI: 10.1038/Nri934  0.446
2002 Pedersen RA. Feeding hungry stem cells. Nature Biotechnology. 20: 882-3. PMID 12205505 DOI: 10.1038/Nbt0902-882  0.45
2001 Weier H, Munné S, Lersch RA, Hsieh H, Smida J, Chen X, Korenberg JR, Pedersen RA, Fung J. Towards a full karyotype screening of interphase cells: 'FISH and chip' technology. Molecular and Cellular Endocrinology. 183: S41-5. PMID 11576731 DOI: 10.1016/S0303-7207(01)00566-4  0.376
2001 Fung J, Weier HU, Pedersen RA. Detection of structural and numerical chromosome abnormalities in interphase cells using spectral imaging. The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society. 49: 797-8. PMID 11373329 DOI: 10.1177/002215540104900616  0.329
2000 Fung J, Weier HUG, Goldberg JD, Pedersen RA. Multilocus genetic analysis of single interphase cells by spectral imaging Human Genetics. 107: 615-622. PMID 11153916 DOI: 10.1007/S004390000416  0.329
2000 Zhong W, Jiang MM, Schonemann MD, Meneses JJ, Pedersen RA, Jan LY, Jan YN. Mouse numb is an essential gene involved in cortical neurogenesis. Proceedings of the National Academy of Sciences of the United States of America. 97: 6844-9. PMID 10841580 DOI: 10.1073/Pnas.97.12.6844  0.417
2000 Hong NA, Flannery M, Hsieh SN, Cado D, Pedersen R, Winoto A. Mice lacking Dad1, the defender against apoptotic death-1, express abnormal N-linked glycoproteins and undergo increased embryonic apoptosis. Developmental Biology. 220: 76-84. PMID 10720432 DOI: 10.1006/Dbio.2000.9615  0.391
2000 Lavoir MC, Conaghan J, Pedersen RA. Culture of human embryos for studies on the derivation of human pluripotent cells: a preliminary investigation. Reproduction, Fertility, and Development. 10: 557-61. PMID 10612461 DOI: 10.1071/rd98083  0.365
2000 Boucher DM, Schaffer M, Deissler K, Moore CA, Gold JD, Burdsal CA, Meneses JJ, Pedersen RA, Blum M. goosecoid expression represses Brachyury in embryonic stem cells and affects craniofacial development in chimeric mice The International Journal of Developmental Biology. 44: 279-288. DOI: 10.1387/Ijdb.10853824  0.526
1999 Tebbs RS, Cleaver JE, Pedersen RA, Hartmann A. Modification of the Comet assay for the detection of DNA strand breaks in extremely small tissue samples. Mutagenesis. 14: 437-8. PMID 10390513 DOI: 10.1093/Mutage/14.4.437  0.349
1999 Shamanski FL, Kimura Y, Lavoir MC, Pedersen RA, Yanagimachi R. Status of genomic imprinting in mouse spermatids. Human Reproduction (Oxford, England). 14: 1050-6. PMID 10221240 DOI: 10.1093/Humrep/14.4.1050  0.381
1999 Pedersen RA. Embryonic stem cells for medicine. Scientific American. 280: 68-73. PMID 10201118 DOI: 10.1038/Scientificamerican0499-68  0.451
1999 Tebbs RS, Flannery ML, Meneses JJ, Hartmann A, Tucker JD, Thompson LH, Cleaver JE, Pedersen RA. Requirement for the Xrcc1 DNA base excision repair gene during early mouse development. Developmental Biology. 208: 513-29. PMID 10191063 DOI: 10.1006/Dbio.1999.9232  0.39
1999 Kim H, Klimanskaya I, Damsky C, Pedersen R, Lebo R. Preimplantation diagnosis of the β1 integrin knockout mutation as a model for aneuploid gene testing Human Genetics. 105: 480-488. DOI: 10.1007/S004399900114  0.334
1998 Ludwig DL, MacInnes MA, Takiguchi Y, Purtymun PE, Henrie M, Flannery M, Meneses J, Pedersen RA, Chen DJ. A murine AP-endonuclease gene-targeted deficiency with post-implantation embryonic progression and ionizing radiation sensitivity Mutation Research - Dna Repair. 409: 17-29. PMID 9806499 DOI: 10.1016/S0921-8777(98)00039-1  0.411
1998 Fung J, Hyun W, Dandekar P, Pedersen RA, Weier HU. Spectral imaging in preconception/preimplantation genetic diagnosis of aneuploidy: multicolor, multichromosome screening of single cells. Journal of Assisted Reproduction and Genetics. 15: 323-30. PMID 9604769 DOI: 10.1023/A:1022508930762  0.305
1998 Burdsal CA, Flannery ML, Pedersen RA. FGF-2 alters the fate of mouse epiblast from ectoderm to mesoderm in vitro Developmental Biology. 198: 231-244. DOI: 10.1016/S0012-1606(98)80001-8  0.765
1997 Sago H, Kim HS, Goldberg JD, Chung JH, Pedersen RA, Lebo RV. Dual blastomer analysis improves reliability of preimplantation trembler mouse diagnosis Human Genetics. 101: 223-228. PMID 9402975 DOI: 10.1007/S004390050620  0.34
1997 Anderson SA, Qiu M, Bulfone A, Eisenstat DD, Meneses J, Pedersen R, Rubenstein JL. Mutations of the homeobox genes Dlx-1 and Dlx-2 disrupt the striatal subventricular zone and differentiation of late born striatal neurons. Neuron. 19: 27-37. PMID 9247261 DOI: 10.1016/S0896-6273(00)80345-1  0.329
1997 Qiu M, Bulfone A, Ghattas I, Meneses JJ, Christensen L, Sharpe PT, Presley R, Pedersen RA, Rubenstein JL. Role of the Dlx homeobox genes in proximodistal patterning of the branchial arches: mutations of Dlx-1, Dlx-2, and Dlx-1 and -2 alter morphogenesis of proximal skeletal and soft tissue structures derived from the first and second arches. Developmental Biology. 185: 165-84. PMID 9187081 DOI: 10.1006/Dbio.1997.8556  0.337
1997 Selwood L, Robinson ES, Pedersen RA, Vandeberg JL. Development in vitro of Marsupials: a comparative review of species and a timetable of cleavage and early blastocyst stages of development in Monodelphis domestica. The International Journal of Developmental Biology. 41: 397-410. DOI: 10.1387/Ijdb.9184350  0.412
1996 Latimer JJ, Hultner ML, Cleaver JE, Pedersen RA. Elevated DNA excision repair capacity in the extraembryonic mesoderm of the midgestation mouse embryo. Experimental Cell Research. 228: 19-28. PMID 8892966 DOI: 10.1006/Excr.1996.0294  0.386
1996 Boucher DM, Pedersen RA. Induction and differentiation of extra-embryonic mesoderm in the mouse Reproduction, Fertility and Development. 8: 765-777. PMID 8870097 DOI: 10.1071/Rd9960765  0.41
1996 Spindle A, Sturm KS, Flannery M, Meneses JJ, Wu K, Pedersen RA. Defective chorioallantoic fusion in mid-gestation lethality of parthenogenone<-->tetraploid chimeras. Developmental Biology. 173: 447-58. PMID 8606004 DOI: 10.1006/Dbio.1996.0039  0.422
1995 Burdsal CA, Pedersen RA, Hyun WC, Latimer JJ. Novel flow-cytometric method for separating cell types in differentiated F9 embryoid bodies Cytometry. 21: 145-152. PMID 8582234 DOI: 10.1002/Cyto.990210206  0.394
1995 Villar AJ, Pedersen RA. Parental imprinting of the Mas protooncogene in mouse. Nature Genetics. 8: 373-9. PMID 7894489 DOI: 10.1038/Ng1294-373  0.351
1995 Gold JD, Pedersen RA. Mechanisms of genomic imprinting in mammals. Current Topics in Developmental Biology. 29: 227-80. PMID 7828439 DOI: 10.1016/S0070-2153(08)60552-9  0.331
1995 Sturm KS, Flannery ML, Pedersen RA. Abnormal development of embryonic and extraembryonic cell lineages in parthenogenetic mouse embryos. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 201: 11-28. PMID 7803844 DOI: 10.1002/Aja.1002010103  0.468
1995 Miettinen PJ, Berger JE, Meneses J, Phung Y, Pedersen RA, Werb Z, Derynck R. Epithelial immaturity and multiorgan failure in mice lacking epidermal growth factor receptor. Nature. 376: 337-41. PMID 7630400 DOI: 10.1038/376337A0  0.314
1995 Qiu M, Bulfone A, Martinez S, Meneses JJ, Shimamura K, Pedersen RA, Rubenstein JL. Null mutation of Dlx-2 results in abnormal morphogenesis of proximal first and second branchial arch derivatives and abnormal differentiation in the forebrain. Genes & Development. 9: 2523-38. PMID 7590232 DOI: 10.1101/Gad.9.20.2523  0.385
1995 Villar AJ, Eddy EM, Pedersen RA. Developmental regulation of genomic imprinting during gametogenesis. Developmental Biology. 172: 264-71. PMID 7589806 DOI: 10.1006/Dbio.1995.0021  0.302
1995 Pedersen RA. Studies of in vitro differentiation with embryonic stem cells. Reproduction, Fertility, and Development. 6: 543-52. PMID 7569032 DOI: 10.1071/Rd9940543  0.532
1995 Carey FJ, Linney EA, Pedersen RA. Allocation of epiblast cells to germ layer derivatives during mouse gastrulation as studied with a retroviral vector. Developmental Genetics. 17: 29-37. PMID 7554493 DOI: 10.1002/Dvg.1020170105  0.421
1995 Stephens LE, Sutherland AE, Klimanskaya IV, Andrieux A, Meneses J, Pedersen RA, Damsky CH. Deletion of beta 1 integrins in mice results in inner cell mass failure and peri-implantation lethality. Genes & Development. 9: 1883-95. PMID 7544312 DOI: 10.1101/Gad.9.15.1883  0.364
1994 Mate KE, Robinson ES, Vandeberg JL, Pedersen RA. Timetable of in vivo embryonic development in the grey short-tailed opossum (Monodelphis domestica). Molecular Reproduction and Development. 39: 365-74. PMID 7893485 DOI: 10.1002/Mrd.1080390404  0.365
1994 Thorey IS, Meneses JJ, Neznanov N, Kulesh DA, Pedersen RA, Oshima RG. Embryonic expression of human keratin 18 and K18-beta-galactosidase fusion genes in transgenic mice. Developmental Biology. 160: 519-34. PMID 7504637 DOI: 10.1006/Dbio.1993.1326  0.33
1992 Lawson KA, Pedersen RA. Clonal analysis of cell fate during gastrulation and early neurulation in the mouse Ciba Foundation Symposium. 165: 3-21; discussion 21. PMID 1516475 DOI: 10.1002/9780470514221.ch2  0.347
1992 Rappolee DA, Sturm KS, Behrendtsen O, Schultz GA, Pedersen RA, Werb Z. Insulin-like growth factor II acts through an endogenous growth pathway regulated by imprinting in early mouse embryos. Genes & Development. 6: 939-52. PMID 1317321 DOI: 10.1101/Gad.6.6.939  0.316
1992 Thorey IS, Pedersen RA, Linney E, Oshima RG. Parent-specific expression of a human keratin 18/beta-galactosidase fusion gene in transgenic mice. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 195: 100-12. PMID 1284293 DOI: 10.1002/Aja.1001950204  0.329
1991 Nielsen LL, Pedersen RA. Drosophila alcohol dehydrogenase: A novel reporter gene for use in mammalian embryos Journal of Experimental Zoology. 257: 128-133. PMID 1846008 DOI: 10.1002/Jez.1402570117  0.336
1991 Nielsen LL, Werb Z, Pedersen RA. Induction of c-fos transcripts in early postimplantation mouse embryos by TGF-α, EGF, PDGF, and FGF Molecular Reproduction and Development. 29: 227-237. PMID 1657054 DOI: 10.1002/Mrd.1080290304  0.356
1989 Brenner CA, Adler RR, Rappolee DA, Pedersen RA, Werb Z. Genes for extracellular-matrix-degrading metalloproteinases and their inhibitor, TIMP, are expressed during early mammalian development. Genes & Development. 3: 848-59. PMID 2744464 DOI: 10.1101/Gad.3.6.848  0.409
1989 Stevens ME, Meneses JJ, Pedersen RA. Expression of a mouse metallothionein-Escherichia coli beta-galactosidase fusion gene (MT-beta gal) in early mouse embryos. Experimental Cell Research. 183: 319-25. PMID 2504613 DOI: 10.1016/0014-4827(89)90392-3  0.365
1989 Rappolee D, Werb Z, Pedersen R, Sturm K, Schultz G. Expression of genes for growth factors and their receptors in preimplantation mouse embryos Cell Differentiation and Development. 27: 12. DOI: 10.1016/0922-3371(89)90073-7  0.348
1988 Winkel GK, Pedersen RA. Fate of the inner cell mass in mouse embryos as studied by microinjection of lineage tracers Developmental Biology. 127: 143-156. PMID 2452102 DOI: 10.1016/0012-1606(88)90196-0  0.51
1986 Lawson KA, Meneses JJ, Pedersen RA. Cell fate and cell lineage in the endoderm of the presomite mouse embryo, studied with an intracellular tracer Developmental Biology. 115: 325-339. PMID 3709966 DOI: 10.1016/0012-1606(86)90253-8  0.452
1986 Pedersen RA, Wu K, Bałakier H. Origin of the inner cell mass in mouse embryos: cell lineage analysis by microinjection. Developmental Biology. 117: 581-95. PMID 2428686 DOI: 10.1016/0012-1606(86)90327-1  0.482
1985 Meneses JJ, Pedersen RA. Ascites tumor fluid and bovine serum albumin as supplements in presomite mouse embryo cultures. The Journal of Experimental Zoology. 231: 355-62. PMID 6502087 DOI: 10.1002/Jez.1402310309  0.388
1985 Spindle A, Nagano H, Pedersen RA. Inhibition of DNA replication in preimplantation mouse embryos by aphidicolin. The Journal of Experimental Zoology. 235: 289-95. PMID 3932586 DOI: 10.1002/Jez.1402350216  0.431
1985 Pedersen RA, Meneses J, Spindle A, Wu K, Galloway SM. Cytochrome P-450 metabolic activity in embryonic and extraembryonic tissue lineages of mouse embryos. Proceedings of the National Academy of Sciences of the United States of America. 82: 3311-5. PMID 3858824 DOI: 10.1073/Pnas.82.10.3311  0.364
1985 Cruz YP, Pedersen RA. Cell fate in the polar trophectoderm of mouse blastocysts as studied by microinjection of cell lineage tracers. Developmental Biology. 112: 73-83. PMID 2414144 DOI: 10.1016/0012-1606(85)90120-4  0.433
1984 Bennett J, Pedersen RA. Early mouse embryos exhibit strain variation in radiation-induced sister-chromatid exchange: relationship with DNA repair. Mutation Research. 126: 153-7. PMID 6538931 DOI: 10.1016/0027-5107(84)90057-5  0.505
1983 Spindle A, Wu K, Pedersen RA. Sensitivity of early mouse embryos to [3H]thymidine. Experimental Cell Research. 142: 397-405. PMID 7173331 DOI: 10.1016/0014-4827(82)90381-0  0.386
1982 Bałakier H, Pedersen RA. Allocation of cells to inner cell mass and trophectoderm lineages in preimplantation mouse embryos. Developmental Biology. 90: 352-62. PMID 7075865 DOI: 10.1016/0012-1606(82)90384-0  0.475
1981 Glass RH, Spindle AI, Maglio M, Pedersen RA. The free surface of mouse trophoblast in culture is non-adhesive for other cells. Journal of Reproduction and Fertility. 59: 403-7. PMID 7431297 DOI: 10.1530/Jrf.0.0590403  0.41
1981 Kubo H, Spindle A, Pedersen RA. Inhibition of mouse blastocyst attachment and outgrowth by protease inhibitors. The Journal of Experimental Zoology. 216: 445-51. PMID 7024469 DOI: 10.1002/Jez.1402160313  0.306
1980 Pedersen RA, Spindle AI. Role of the blastocoele microenvironment in early mouse embryo differentiation. Nature. 284: 550-2. PMID 7366723 DOI: 10.1038/284550A0  0.484
1980 Sobel JS, Cooke R, Pedersen RA. Distribution of actin and myosin in mouse trophoblast: correlation with changes in invasiveness during development in vitro. Developmental Biology. 78: 365-79. PMID 6997113 DOI: 10.1016/0012-1606(80)90341-3  0.327
1980 Galloway SM, Perry PE, Meneses J, Nebert DW, Pedersen RA. Cultured mouse embryos metabolize benzo[a]pyrene during early gestation: genetic differences detectable by sister chromatid exchange. Proceedings of the National Academy of Sciences of the United States of America. 77: 3524-8. PMID 6932035 DOI: 10.1073/Pnas.77.6.3524  0.394
1979 Glass RH, Spindle AI, Pedersen RA. Mouse embryo attachment to substratum and interaction of trophoblast with cultured cells. The Journal of Experimental Zoology. 208: 327-36. PMID 582831 DOI: 10.1002/Jez.1402080309  0.479
1978 Wiley LM, Spindle AI, Pedersen RA. Morphology of isolated mouse inner cell masses developing in vitro Developmental Biology. 63: 1-10. PMID 631422 DOI: 10.1016/0012-1606(78)90108-2  0.423
1978 Goldstein LS, Meneses J, Pedersen RA. Dose-response relationship for X-ray induced dominant lethal mutations detected in mouse embryos in vitro. Mutation Research. 51: 55-9. PMID 566851 DOI: 10.1016/0027-5107(78)90008-8  0.325
1977 Glass RH, Spindle AI, Pedersen RA. Differential inhibition of trophoblast outgrowth and inner cell mass growth by actinomycin D in cultured mouse embryos. Journal of Reproduction and Fertility. 48: 443-5. PMID 1033287 DOI: 10.1530/Jrf.0.0480443  0.41
1977 Pedersen RA, Spindle AI, Wiley LM. Regeneration of endoderm by ectoderm isolated from mouse blastocysts Nature. 270: 435-437. PMID 593361 DOI: 10.1038/270435A0  0.486
1977 Wiley LM, Pedersen RA. Morphology of mouse egg cylinder development in vitro: a light and electron microscopic study Journal of Experimental Zoology. 200: 389-402. PMID 327020 DOI: 10.1002/Jez.1402000309  0.396
1976 Pedersen RA, Cleaver JE. Reparir of UV damage to DNA of implantation-stage mouse embryos in vitro. Experimental Cell Research. 95: 247-53. PMID 1238275 DOI: 10.1016/0014-4827(75)90548-0  0.339
1975 Masui Y, Pedersen RA. Ultraviolet light-induced unscheduled DNA synthesis in mouse oocytes during meiotic maturation. Nature. 257: 705-706. PMID 1237799 DOI: 10.1038/257705A0  0.314
1975 Erickson RP, Pedersen RA. In vitro development of t6/t6 embryos. The Journal of Experimental Zoology. 193: 377-84. PMID 1176911 DOI: 10.1002/Jez.1401930314  0.369
1975 Goldstein LS, Spindle AI, Pedersen RA. X-ray sensitivity of the preimplantation mouse embryo in vitro. Radiation Research. 62: 276-87. PMID 1091945 DOI: 10.2307/3574220  0.442
1974 Pedersen RA. Development of lethal yellow (Ay-Ay) mouse embryos in vitro. The Journal of Experimental Zoology. 188: 307-20. PMID 4836190 DOI: 10.1002/Jez.1401880307  0.45
1974 Spindle AI, Pedersen RA. Hatching, attachment, and outgrowth of mouse blastocysts in vitro: fixed nitrogen requirements. The Journal of Experimental Zoology. 186: 305-18. PMID 4765353 DOI: 10.1002/Jez.1401860308  0.332
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