| Year |
Citation |
Score |
| 2021 |
Bhattacharyya A, Trotta CR, Narasimhan J, Wiedinger KJ, Li W, Effenberger KA, Woll MG, Jani MB, Risher N, Yeh S, Cheng Y, Sydorenko N, Moon YC, Karp GM, Weetall M, ... ... Peltz SW, et al. Small molecule splicing modifiers with systemic HTT-lowering activity. Nature Communications. 12: 7299. PMID 34911927 DOI: 10.1038/s41467-021-27157-z |
0.319 |
|
| 2020 |
Luban J, Sattler R, Mühlberger E, Graci JD, Cao L, Weetall M, Trotta C, Colacino JM, Bavari S, Strambio-De-Castillia C, Suder EL, Wang Y, Soloveva V, Cintron-Lue K, Naryshkin NA, ... ... Peltz S, et al. The DHODH Inhibitor PTC299 Arrests SARS-CoV-2 Replication and Suppresses Induction of Inflammatory Cytokines. Virus Research. 198246. PMID 33249060 DOI: 10.1016/j.virusres.2020.198246 |
0.705 |
|
| 2020 |
Luban J, Sattler R, Mühlberger E, Graci JD, Cao L, Weetall M, Trotta C, Colacino JM, Bavari S, Strambio-De-Castillia C, Suder EL, Wang Y, Soloveva V, Cintron-Lue K, Naryshkin NA, ... ... Peltz S, et al. The DHODH Inhibitor PTC299 Arrests SARS-CoV-2 Replication and Suppresses Induction of Inflammatory Cytokines. Biorxiv : the Preprint Server For Biology. PMID 32793904 DOI: 10.1101/2020.08.05.238394 |
0.705 |
|
| 2018 |
Friesen WJ, Johnson B, Sierra J, Zhuo J, Vazirani P, Xue X, Tomizawa Y, Baiazitov R, Morrill C, Ren H, Babu S, Moon YC, Branstrom A, Mollin A, Hedrick J, ... ... Peltz SW, et al. The minor gentamicin complex component, X2, is a potent premature stop codon readthrough molecule with therapeutic potential. Plos One. 13: e0206158. PMID 30359426 DOI: 10.1371/Journal.Pone.0206158 |
0.669 |
|
| 2018 |
Cao L, Weetall M, Trotta C, Cintron K, Ma J, Kim MJ, Furia B, Romfo C, Graci JD, Li W, Du J, Sheedy J, Hedrick J, Risher N, Yeh S, ... ... Peltz SW, et al. Targeting of Hematologic Malignancies with PTC299, A Novel Potent Inhibitor of Dihydroorotate Dehydrogenase with Favorable Pharmaceutical Properties. Molecular Cancer Therapeutics. PMID 30352802 DOI: 10.1158/1535-7163.Mct-18-0863 |
0.581 |
|
| 2017 |
McDonald CM, Campbell C, Torricelli RE, Finkel RS, Flanigan KM, Goemans N, Heydemann P, Kaminska A, Kirschner J, Muntoni F, Osorio AN, Schara U, Sejersen T, Shieh PB, Sweeney HL, ... ... Peltz SW, et al. Ataluren in patients with nonsense mutation Duchenne muscular dystrophy (ACT DMD): a multicentre, randomised, double-blind, placebo-controlled, phase 3 trial. Lancet (London, England). PMID 28728956 DOI: 10.1016/S0140-6736(17)31611-2 |
0.34 |
|
| 2017 |
Friesen WJ, Trotta CR, Tomizawa Y, Zhuo J, Johnson B, Sierra J, Roy B, Weetall M, Hedrick J, Sheedy J, Takasugi J, Moon YC, Babu S, Baiazitov R, Leszyk JD, ... ... Peltz SW, et al. The nucleoside analog clitocine is a potent and efficacious readthrough agent. Rna (New York, N.Y.). PMID 28096517 DOI: 10.1261/Rna.060236.116 |
0.698 |
|
| 2017 |
Cao L, Branstrom A, Baird J, Trotta C, Colacino J, Santaguida MT, Heiser D, Ma M, Kojima K, Peltz S, O'Mara E, Spiegel R, Weetall M. PTC299 Is a Novel DHODH Inhibitor That Modulates VEGFA mRNA Translation and Inhibits Proliferation of a Broad Range of Leukemia Cells Blood. 130: 1371-1371. DOI: 10.1182/Blood.V130.Suppl_1.1371.1371 |
0.394 |
|
| 2016 |
Cao L, Weetall M, Bombard J, Qi H, Arasu T, Lennox W, Hedrick J, Sheedy J, Risher N, Brooks PC, Trifillis P, Trotta C, Moon YC, Babiak J, Almstead NG, ... ... Peltz SW, et al. Discovery of Novel Small Molecule Inhibitors of VEGF Expression in Tumor Cells Using a Cell-Based High Throughput Screening Platform. Plos One. 11: e0168366. PMID 27992500 DOI: 10.1371/Journal.Pone.0168366 |
0.316 |
|
| 2016 |
Weetall M, Davis T, Elfring G, Northcutt V, Cao L, Moon YC, Riebling P, Dali M, Hirawat S, Babiak J, Colacino J, Almstead N, Spiegel R, Peltz SW. Phase 1 Study of Safety, Tolerability, and Pharmacokinetics of PTC299, an Inhibitor of Stress-Regulated Protein Translation. Clinical Pharmacology in Drug Development. 5: 296-305. PMID 27310330 DOI: 10.1002/Cpdd.240 |
0.333 |
|
| 2014 |
Naryshkin NA, Weetall M, Dakka A, Narasimhan J, Zhao X, Feng Z, Ling KK, Karp GM, Qi H, Woll MG, Chen G, Zhang N, Gabbeta V, Vazirani P, Bhattacharyya A, ... ... Peltz SW, et al. Motor neuron disease. SMN2 splicing modifiers improve motor function and longevity in mice with spinal muscular atrophy. Science (New York, N.Y.). 345: 688-93. PMID 25104390 DOI: 10.1126/Science.1250127 |
0.674 |
|
| 2014 |
Bushby K, Finkel R, Wong B, Barohn R, Campbell C, Comi GP, Connolly AM, Day JW, Flanigan KM, Goemans N, Jones KJ, Mercuri E, Quinlivan R, Renfroe JB, Russman B, ... ... Peltz SW, et al. Ataluren treatment of patients with nonsense mutation dystrophinopathy. Muscle & Nerve. 50: 477-87. PMID 25042182 DOI: 10.1002/Mus.24332 |
0.341 |
|
| 2014 |
Kerem E, Konstan MW, De Boeck K, Accurso FJ, Sermet-Gaudelus I, Wilschanski M, Elborn JS, Melotti P, Bronsveld I, Fajac I, Malfroot A, Rosenbluth DB, Walker PA, McColley SA, Knoop C, ... ... Peltz SW, et al. Ataluren for the treatment of nonsense-mutation cystic fibrosis: a randomised, double-blind, placebo-controlled phase 3 trial. The Lancet. Respiratory Medicine. 2: 539-47. PMID 24836205 DOI: 10.1016/S2213-2600(14)70100-6 |
0.67 |
|
| 2013 |
Finkel RS, Flanigan KM, Wong B, Bönnemann C, Sampson J, Sweeney HL, Reha A, Northcutt VJ, Elfring G, Barth J, Peltz SW. Phase 2a study of ataluren-mediated dystrophin production in patients with nonsense mutation Duchenne muscular dystrophy. Plos One. 8: e81302. PMID 24349052 DOI: 10.1371/Journal.Pone.0081302 |
0.42 |
|
| 2013 |
Peltz SW, Morsy M, Welch EM, Jacobson A. Ataluren as an agent for therapeutic nonsense suppression. Annual Review of Medicine. 64: 407-25. PMID 23215857 DOI: 10.1146/Annurev-Med-120611-144851 |
0.786 |
|
| 2010 |
Wang B, Yang Z, Brisson BK, Feng H, Zhang Z, Welch EM, Peltz SW, Barton ER, Brown RH, Sweeney HL. Membrane blebbing as an assessment of functional rescue of dysferlin-deficient human myotubes via nonsense suppression. Journal of Applied Physiology (Bethesda, Md. : 1985). 109: 901-5. PMID 20558759 DOI: 10.1152/Japplphysiol.01366.2009 |
0.674 |
|
| 2009 |
Peltz SW, Welch EM, Trotta CR, Davis T, Jacobson A. Targeting post-transcriptional control for drug discovery. Rna Biology. 6: 329-34. PMID 19574739 DOI: 10.4161/Rna.6.3.8953 |
0.769 |
|
| 2009 |
Peltz SW, Welch EM, Jacobson A, Trotta CR, Naryshkin N, Sweeney HL, Bedwell DM. Nonsense suppression activity of PTC124 (ataluren). Proceedings of the National Academy of Sciences of the United States of America. 106: E64; author reply E6. PMID 19506240 DOI: 10.1073/Pnas.0901936106 |
0.724 |
|
| 2009 |
Kerem E, Kerem B, Welch EM, Trotta C, Weetall M, Miller L, Jacobson A, Peltz SW. PTC124 for cystic fibrosis - Authors' reply The Lancet. 373: 1426-1427. PMID 19394530 DOI: 10.1016/S0140-6736(09)60820-5 |
0.69 |
|
| 2008 |
Du M, Liu X, Welch EM, Hirawat S, Peltz SW, Bedwell DM. PTC124 is an orally bioavailable compound that promotes suppression of the human CFTR-G542X nonsense allele in a CF mouse model. Proceedings of the National Academy of Sciences of the United States of America. 105: 2064-9. PMID 18272502 DOI: 10.1073/Pnas.0711795105 |
0.701 |
|
| 2007 |
Bhattacharyya A, Trotta CR, Peltz SW. Mining the GEMS--a novel platform technology targeting post-transcriptional control mechanisms. Drug Discovery Today. 12: 553-60. PMID 17631250 DOI: 10.1016/J.Drudis.2007.05.009 |
0.405 |
|
| 2007 |
Welch EM, Barton ER, Zhuo J, Tomizawa Y, Friesen WJ, Trifillis P, Paushkin S, Patel M, Trotta CR, Hwang S, Wilde RG, Karp G, Takasugi J, Chen G, Jones S, ... ... Peltz SW, et al. PTC124 targets genetic disorders caused by nonsense mutations. Nature. 447: 87-91. PMID 17450125 DOI: 10.1038/Nature05756 |
0.77 |
|
| 2007 |
Hirawat S, Welch EM, Elfring GL, Northcutt VJ, Paushkin S, Hwang S, Leonard EM, Almstead NG, Ju W, Peltz SW, Miller LL. Safety, tolerability, and pharmacokinetics of PTC124, a nonaminoglycoside nonsense mutation suppressor, following single- and multiple-dose administration to healthy male and female adult volunteers. Journal of Clinical Pharmacology. 47: 430-44. PMID 17389552 DOI: 10.1177/0091270006297140 |
0.654 |
|
| 2007 |
Pelletier J, Peltz SW. 30 Therapeutic Opportunities in Translation Cold Spring Harbor Monograph Archive. 48: 855-895. DOI: 10.1101/087969767.48.855 |
0.442 |
|
| 2006 |
Trotta CR, Paushkin SV, Patel M, Li H, Peltz SW. Cleavage of pre-tRNAs by the splicing endonuclease requires a composite active site. Nature. 441: 375-7. PMID 16710424 DOI: 10.1038/Nature04741 |
0.328 |
|
| 2006 |
Wang W, Cajigas IJ, Peltz SW, Wilkinson MF, González CI. Role for Upf2p phosphorylation in Saccharomyces cerevisiae nonsense-mediated mRNA decay. Molecular and Cellular Biology. 26: 3390-400. PMID 16611983 DOI: 10.1128/Mcb.26.9.3390-3400.2006 |
0.363 |
|
| 2006 |
Mehta A, Trotta CR, Peltz SW. Derepression of the Her-2 uORF is mediated by a novel post-transcriptional control mechanism in cancer cells. Genes & Development. 20: 939-53. PMID 16598037 DOI: 10.1101/Gad.1388706 |
0.429 |
|
| 2005 |
Vasudevan S, Garneau N, Tu Khounh D, Peltz SW. p38 mitogen-activated protein kinase/Hog1p regulates translation of the AU-rich-element-bearing MFA2 transcript. Molecular and Cellular Biology. 25: 9753-63. PMID 16260593 DOI: 10.1128/Mcb.25.22.9753-9763.2005 |
0.356 |
|
| 2005 |
Duttagupta R, Tian B, Wilusz CJ, Khounh DT, Soteropoulos P, Ouyang M, Dougherty JP, Peltz SW. Global analysis of Pub1p targets reveals a coordinate control of gene expression through modulation of binding and stability. Molecular and Cellular Biology. 25: 5499-513. PMID 15964806 DOI: 10.1128/Mcb.25.13.5499-5513.2005 |
0.42 |
|
| 2004 |
Paushkin SV, Patel M, Furia BS, Peltz SW, Trotta CR. Identification of a human endonuclease complex reveals a link between tRNA splicing and pre-mRNA 3' end formation. Cell. 117: 311-21. PMID 15109492 DOI: 10.1016/S0092-8674(04)00342-3 |
0.432 |
|
| 2004 |
Biswas P, Jiang X, Pacchia AL, Dougherty JP, Peltz SW. The Human Immunodeficiency Virus Type 1 Ribosomal Frameshifting Site Is an Invariant Sequence Determinant and an Important Target for Antiviral Therapy Journal of Virology. 78: 2082-2087. PMID 14747573 DOI: 10.1128/Jvi.78.4.2082-2087.2004 |
0.326 |
|
| 2003 |
Vasudevan S, Peltz SW. Nuclear mRNA surveillance. Current Opinion in Cell Biology. 15: 332-7. PMID 12787776 DOI: 10.1016/S0955-0674(03)00051-6 |
0.444 |
|
| 2003 |
González CI, Wang W, Peltz SW. Nonsense-mediated mRNA decay in Saccharomyces cerevisiae: a quality control mechanism that degrades transcripts harboring premature termination codons. Cold Spring Harbor Symposia On Quantitative Biology. 66: 321-8. PMID 12762034 DOI: 10.1101/SQB.2001.66.321 |
0.305 |
|
| 2003 |
Duttagupta R, Vasudevan S, Wilusz CJ, Peltz SW. A yeast homologue of Hsp70, Ssa1p, regulates turnover of the MFA2 transcript through its AU-rich 3' untranslated region. Molecular and Cellular Biology. 23: 2623-32. PMID 12665566 DOI: 10.1128/Mcb.23.8.2623-2632.2003 |
0.454 |
|
| 2002 |
Vasudevan S, Peltz SW, Wilusz CJ. Non-stop decay--a new mRNA surveillance pathway. Bioessays : News and Reviews in Molecular, Cellular and Developmental Biology. 24: 785-8. PMID 12210514 DOI: 10.1002/Bies.10153 |
0.455 |
|
| 2001 |
Wilusz CJ, Wang W, Peltz SW. Curbing the nonsense: The activation and regulation of mRNA surveillance Genes and Development. 15: 2781-2785. PMID 11691829 DOI: 10.1101/Gad.943701 |
0.509 |
|
| 2001 |
González CI, Bhattacharya A, Wang W, Peltz SW. Nonsense-mediated mRNA decay in Saccharomyces cerevisiae. Gene. 274: 15-25. PMID 11674994 DOI: 10.1016/S0378-1119(01)00552-2 |
0.456 |
|
| 2001 |
Vasudevan S, Peltz SW. Regulated ARE-mediated mRNA decay in Saccharomyces cerevisiae Molecular Cell. 7: 1191-1200. PMID 11430822 DOI: 10.1016/S1097-2765(01)00279-9 |
0.373 |
|
| 2001 |
Ruiz-Echevarria MJ, Munshi R, Tomback J, Kinzy TG, Peltz SW. Characterization of a general stabilizer element that blocks deadenylation-dependent mRNA decay. The Journal of Biological Chemistry. 276: 30995-1003. PMID 11423548 DOI: 10.1074/Jbc.M010833200 |
0.414 |
|
| 2001 |
Wilusz CJ, Wormington M, Peltz SW. The cap-to-tail guide to mRNA turnover Nature Reviews Molecular Cell Biology. 2: 237-246. PMID 11283721 DOI: 10.1038/35067025 |
0.341 |
|
| 2001 |
Gao M, Wilusz CJ, Peltz SW, Wilusz J. A novel mRNA-decapping activity in HeLa cytoplasmic extracts is regulated by AU-rich elements Embo Journal. 20: 1134-1143. PMID 11230136 DOI: 10.1093/Emboj/20.5.1134 |
0.306 |
|
| 2001 |
Wang W, Czaplinski K, Rao Y, Peltz SW. The role of Upf proteins in modulating the translation read-through of nonsense-containing transcripts Embo Journal. 20: 880-890. PMID 11179232 DOI: 10.1093/Emboj/20.4.880 |
0.395 |
|
| 2001 |
Dinman J, Ruiz-Echevarria M, Wang W, Peltz S. The case for the involvement of the Upf3p in programmed -1 ribosomal frameshifting. Rna (New York, N.Y.). 6: 1685-6. PMID 11142366 DOI: 10.1017/S1355838200001886 |
0.589 |
|
| 2000 |
Bhattacharya A, Czaplinski K, Trifillis P, He F, Jacobson A, Peltz SW. Characterization of the biochemical properties of the human Upf1 gene product that is involved in nonsense-mediated mRNA decay Rna. 6: 1226-1235. PMID 10999600 DOI: 10.1017/S1355838200000546 |
0.628 |
|
| 2000 |
Ruiz-Echevarría MJ, Peltz SW. The RNA binding protein Pub1 modulates the stability of transcripts containing upstream open reading frames. Cell. 101: 741-51. PMID 10892745 DOI: 10.1016/S0092-8674(00)80886-7 |
0.362 |
|
| 2000 |
González CI, Ruiz-Echevarría MJ, Vasudevan S, Henry MF, Peltz SW. The yeast hnRNP-like protein Hrp1/Nab4 marks a transcript for nonsense-mediated mRNA decay. Molecular Cell. 5: 489-99. PMID 10882134 DOI: 10.1016/S1097-2765(00)80443-8 |
0.466 |
|
| 2000 |
Czaplinski K, Majlesi N, Banerjee T, Peltz SW. Mtt1 is a Upf1-like helicase that interacts with the translation termination factors and whose overexpression can modulate termination efficiency Rna. 6: 730-743. PMID 10836794 DOI: 10.1017/S1355838200992392 |
0.456 |
|
| 2000 |
Jacobson A, Peltz SW. 29 Destabilization of Nonsense-containing Transcripts in Saccharomyces cerevisiae Cold Spring Harbor Monograph Archive. 39: 827-847. DOI: 10.1101/087969618.39.827 |
0.614 |
|
| 2000 |
Welch EM, Wang W, Peltz SW. 11 Translation Termination: It’s Not the End of the Story Cold Spring Harbor Monograph Archive. 39: 467-485. DOI: 10.1101/087969618.39.467 |
0.457 |
|
| 1999 |
Peltz SW, Dougherty JP. Antisense translates into sense Journal of Experimental Medicine. 190: 1729-1731. PMID 10601348 DOI: 10.1084/Jem.190.12.1729 |
0.321 |
|
| 1999 |
Zhang S, Williams CJ, Hagan K, Peltz SW. Mutations in VPS16 and MRT1 stabilize mRNAs by activating an inhibitor of the decapping enzyme. Molecular and Cellular Biology. 19: 7568-76. PMID 10523645 DOI: 10.1128/MCB.19.11.7568 |
0.365 |
|
| 1999 |
Czaplinski K, Ruiz-Echevarria MJ, González CI, Peltz SW. Should we kill the messenger? The role of the surveillance complex in translation termination and mRNA turnover. Bioessays : News and Reviews in Molecular, Cellular and Developmental Biology. 21: 685-96. PMID 10440865 DOI: 10.1002/(Sici)1521-1878(199908)21:8<685::Aid-Bies8>3.0.Co;2-4 |
0.347 |
|
| 1999 |
Cui Y, González CI, Kinzy TG, Dinman JD, Peltz SW. Mutations in the MOF2/SUI1 gene affect both translation and nonsense- mediated mRNA decay Rna. 5: 794-804. PMID 10376878 DOI: 10.1017/S1355838299982055 |
0.693 |
|
| 1999 |
Sheikh MS, Fernandez-Salas E, Yu M, Hussain A, Dinman JD, Peltz SW, Huang Y, Fornace AJ. Cloning and characterization of a human genotoxic and endoplasmic reticulum stress-inducible cDNA that encodes translation initiation factor 1(eIF1(A121/SUI1)) Journal of Biological Chemistry. 274: 16487-16493. PMID 10347211 DOI: 10.1074/Jbc.274.23.16487 |
0.591 |
|
| 1999 |
Hammell AB, Taylor RC, Peltz SW, Dinman JD. Identification of putative programmed -1 ribosomal frameshift signals in large DNA databases. Genome Research. 9: 417-27. PMID 10330121 DOI: 10.1101/Gr.9.5.417 |
0.591 |
|
| 1999 |
Zhang S, Williams CJ, Wormington M, Stevens A, Peltz SW. Monitoring mRNA decapping activity. Methods (San Diego, Calif.). 17: 46-51. PMID 10075882 DOI: 10.1006/meth.1998.0706 |
0.302 |
|
| 1999 |
Jacobson A, Peltz SW. Tools for turnover: methods for analysis of mRNA stability in eukaryotic cells. Methods (San Diego, Calif.). 17: 1-2. PMID 10075876 DOI: 10.1006/Meth.1998.0700 |
0.588 |
|
| 1999 |
Peltz SW, Hammell AB, Cui Y, Yasenchak J, Puljanowski L, Dinman JD. Ribosomal protein L3 mutants alter translational fidelity and promote rapid loss of the yeast killer virus Molecular and Cellular Biology. 19: 384-391. PMID 9858562 DOI: 10.1128/Mcb.19.1.384 |
0.619 |
|
| 1998 |
Ruiz-Echevarría MJ, Yasenchak JM, Han X, Dinman JD, Peltz SW. The upf3 protein is a component of the surveillance complex that monitors both translation and mRNA turnover and affects viral propagation. Proceedings of the National Academy of Sciences of the United States of America. 95: 8721-6. PMID 9671745 DOI: 10.1073/Pnas.95.15.8721 |
0.671 |
|
| 1998 |
Czaplinski K, Ruiz-Echevarria MJ, Paushkin SV, Han X, Weng Y, Perlick HA, Dietz HC, Ter-Avanesyan MD, Peltz SW. The surveillance complex interacts with the translation release factors to enhance termination and degrade aberrant mRNAs. Genes & Development. 12: 1665-77. PMID 9620853 DOI: 10.1101/Gad.12.11.1665 |
0.437 |
|
| 1998 |
Dinman JD, Ruiz-Echevarria MJ, Peltz SW. Translating old drugs into new treatments: ribosomal frameshifting as a target for antiviral agents. Trends in Biotechnology. 16: 190-6. PMID 9586242 DOI: 10.1016/S0167-7799(97)01167-0 |
0.599 |
|
| 1998 |
Cui Y, Dinman JD, Kinzy TG, Peltz SW. The Mof2/Sui1 protein is a general monitor of translational accuracy Molecular and Cellular Biology. 18: 1506-1516. PMID 9488467 DOI: 10.1128/Mcb.18.3.1506 |
0.613 |
|
| 1998 |
Ruiz-Echevarría MJ, González CI, Peltz SW. Identifying the right stop: determining how the surveillance complex recognizes and degrades an aberrant mRNA. The Embo Journal. 17: 575-89. PMID 9430648 DOI: 10.1093/emboj/17.2.575 |
0.319 |
|
| 1997 |
Dinman JD, Ruiz-Echevarria MJ, Czaplinski K, Peltz SW. Peptidyl-transferase inhibitors have antiviral properties by altering programmed -1 ribosomal frameshifting efficiencies: development of model systems. Proceedings of the National Academy of Sciences of the United States of America. 94: 6606-11. PMID 9192612 DOI: 10.1073/Pnas.94.13.6606 |
0.626 |
|
| 1996 |
Ruiz-Echevarria MJ, Czaplinski K, Peltz SW. Making sense of nonsense in yeast. Trends in Biochemical Sciences. 21: 433-8. PMID 8987399 DOI: 10.1016/S0968-0004(96)10055-4 |
0.446 |
|
| 1996 |
Cui Y, Dinman JD, Peltz SW. mof4-1 is an allele of the UPF1/IFS2 gene which affects both mRNA turnover and -1 ribosomal frameshifting efficiency Embo Journal. 15: 5726-5736. PMID 8896465 DOI: 10.1002/J.1460-2075.1996.Tb00956.X |
0.636 |
|
| 1996 |
Weng Y, Czaplinski K, Peltz SW. Identification and characterization of mutations in the UPF1 gene that affect nonsense suppression and the formation of the Upf protein complex but not mRNA turnover Molecular and Cellular Biology. 16: 5491-5506. PMID 8816462 DOI: 10.1128/MCB.16.10.5491 |
0.415 |
|
| 1996 |
Weng Y, Czaplinski K, Peltz SW. Genetic and biochemical characterization of mutations in the ATPase and helicase regions of the Upf1 protein Molecular and Cellular Biology. 16: 5477-5490. PMID 8816461 DOI: 10.1128/Mcb.16.10.5477 |
0.481 |
|
| 1996 |
Jacobson A, Peltz SW. Interrelationships of the pathways of mRNA decay and translation in eukaryotic cells. Annual Review of Biochemistry. 65: 693-739. PMID 8811193 DOI: 10.1146/Annurev.Bi.65.070196.003401 |
0.666 |
|
| 1996 |
Ruiz-Echevarria MJ, Peltz SW. Utilizing the GCN4 leader region to investigate the role of the sequence determinants in nonsense-mediated mRNA decay. The Embo Journal. 15: 2810-9. PMID 8654378 DOI: 10.1002/J.1460-2075.1996.Tb00641.X |
0.449 |
|
| 1995 |
Zhang S, Ruiz-Echevarria MJ, Quan Y, Peltz SW. Identification and characterization of a sequence motif involved in nonsense-mediated mRNA decay. Molecular and Cellular Biology. 15: 2231-44. PMID 7891717 DOI: 10.1128/Mcb.15.4.2231 |
0.397 |
|
| 1995 |
Cui Y, Hagan KW, Zhang S, Peltz SW. Identification and characterization of genes that are required for the accelerated degradation of mRNAs containing a premature translational termination codon. Genes & Development. 9: 423-36. PMID 7883167 DOI: 10.1101/GAD.9.4.423 |
0.379 |
|
| 1995 |
Hagan KW, Ruiz-Echevarria MJ, Quan Y, Peltz SW. Characterization of cis-acting sequences and decay intermediates involved in nonsense-mediated mRNA turnover. Molecular and Cellular Biology. 15: 809-23. PMID 7823948 DOI: 10.1128/Mcb.15.2.809 |
0.484 |
|
| 1994 |
Peltz SW, He F, Welch E, Jacobson A. Nonsense-mediated mRNA decay in yeast. Progress in Nucleic Acid Research and Molecular Biology. 47: 271-98. PMID 8016322 DOI: 10.1016/S0079-6603(08)60254-8 |
0.777 |
|
| 1993 |
Peltz SW, Brown AH, Jacobson A. mRNA destabilization triggered by premature translational termination depends on at least three cis-acting sequence elements and one trans-acting factor. Genes & Development. 7: 1737-54. PMID 8370523 DOI: 10.1101/Gad.7.9.1737 |
0.631 |
|
| 1993 |
He F, Peltz SW, Donahue JL, Rosbash M, Jacobson A. Stabilization and ribosome association of unspliced pre-mRNAs in a yeast upf1- mutant. Proceedings of the National Academy of Sciences of the United States of America. 90: 7034-8. PMID 8346213 DOI: 10.1073/Pnas.90.15.7034 |
0.682 |
|
| 1993 |
Peltz SW, Jacobson A. mRNA stability: in trans-it. Current Opinion in Cell Biology. 4: 979-83. PMID 1485969 DOI: 10.1016/0955-0674(92)90129-Z |
0.647 |
|
| 1993 |
Higgins CF, Peltz SW, Jacobson A. Turnover of mRNA in prokaryotes and lower eukaryotes. Current Opinion in Genetics & Development. 2: 739-47. PMID 1281028 DOI: 10.1016/S0959-437X(05)80134-0 |
0.635 |
|
| 1992 |
Leeds P, Peltz SW, Jacobson A, Culbertson MR. The product of the yeast UPF1 gene is required for rapid turnover of mRNAs containing a premature translational termination codon. Genes & Development. 5: 2303-14. PMID 1748286 DOI: 10.1101/Gad.5.12A.2303 |
0.644 |
|
| 1992 |
Peltz SW, Donahue JL, Jacobson A. A mutation in the tRNA nucleotidyltransferase gene promotes stabilization of mRNAs in Saccharomyces cerevisiae Molecular and Cellular Biology. 12: 5778-5784. PMID 1448105 DOI: 10.1128/Mcb.12.12.5778 |
0.626 |
|
| 1992 |
Higgins CF, Peltz SW, Jacobson A. Turnover of mRNA in prokaryotes and lower eukaryotes Current Biology. 2: 536. DOI: 10.1016/0960-9822(92)90019-7 |
0.627 |
|
| 1991 |
Parker R, Herrick D, Peltz SW, Jacobson A. Measurement of mRNA decay rates in Saccharomyces cerevisiae. Methods in Enzymology. 194: 415-23. PMID 2005800 DOI: 10.1016/0076-6879(91)94032-8 |
0.792 |
|
| 1987 |
Ross J, Peltz SW, Kobs G, Brewer G. Histone mRNA degradation in vivo: the first detectable step occurs at or near the 3' terminus. Molecular and Cellular Biology. 6: 4362-71. PMID 3467177 DOI: 10.1128/MCB.6.12.4362 |
0.3 |
|
| 1985 |
Peltz SW, Brown AL, Hasan N, Podhajska AJ, Szybalski W. Thermosensitivity of a DNA recognition site: activity of a truncated nutL antiterminator of coliphage lambda. Science (New York, N.Y.). 228: 91-3. PMID 3156406 DOI: 10.1126/Science.3156406 |
0.304 |
|
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