| Year |
Citation |
Score |
| 2017 |
Saint-Dizier F, Simpkins NS. First total synthesis of concavine. Chemical Science. 8: 3384-3389. PMID 28507709 DOI: 10.1039/c6sc05627j |
0.367 |
|
| 2017 |
Simpkins NS, Foster R, Lenz E, Stead D. Organocatalytic Stereoconvergent Synthesis of α-CF3 Amides; Triketopiperazines and Their Heterocyclic Metamorphosis. Chemistry (Weinheim An Der Bergstrasse, Germany). PMID 28493292 DOI: 10.1002/chem.201701548 |
0.315 |
|
| 2015 |
Cabanillas A, Davies CD, Male L, Simpkins NS. Highly enantioselective access to diketopiperazinescinchona alkaloid catalyzed Michael additions. Chemical Science. 6: 1350-1354. PMID 29560222 DOI: 10.1039/c4sc03218g |
0.385 |
|
| 2013 |
Hayes CJ, Simpkins NS. Bridgehead enolate or bridgehead organolithium? DFT calculations provide insights into a difficult bridgehead substitution reaction in the synthesis of the polycyclic polyprenylated acylphloroglucinol (PPAP) nemorosone. Organic & Biomolecular Chemistry. 11: 8458-62. PMID 24202405 DOI: 10.1039/C3Ob41064A |
0.349 |
|
| 2013 |
Simpkins NS, Pavlakos I, Weller MD, Male L. The cascade radical cyclisation approach to prenylated alkaloids: synthesis of stephacidin A and notoamide B. Organic & Biomolecular Chemistry. 11: 4957-70. PMID 23797367 DOI: 10.1039/c3ob40979a |
0.321 |
|
| 2013 |
Simpkins NS, Weske DF, Male L, Coles SJ, Pitak MB. Synthesis of fumaramide derived [3]rotaxanes as potential precursors for molecular boxes. Chemical Communications (Cambridge, England). 49: 5010-2. PMID 23620239 DOI: 10.1039/C3Cc42045K |
0.325 |
|
| 2013 |
Simpkins NS. Adventures in bridgehead substitution chemistry: synthesis of polycyclic polyprenylated acylphloroglucinols (PPAPs). Chemical Communications (Cambridge, England). 49: 1042-51. PMID 23229029 DOI: 10.1039/c2cc37914g |
0.346 |
|
| 2012 |
Simpkins N, Pavlakos I, Male L. Rapid access to polycyclic indolines related to the stephacidin alkaloids using a radical cascade. Chemical Communications (Cambridge, England). 48: 1958-60. PMID 22134634 DOI: 10.1039/C1Cc16510K |
0.385 |
|
| 2010 |
Simpkins NS, Taylor JD, Weller MD, Hayes CJ. Synthesis of nemorosone via a difficult bridgehead substitution reaction Synlett. 639-643. DOI: 10.1055/S-0029-1219371 |
0.378 |
|
| 2010 |
Blake AJ, Hume SC, Li W, Simpkins NS. ChemInform Abstract: Enantioselective Synthesis of Phospholanes Using Chiral Lithium Amide Desymmetrization. Cheminform. 33: no-no. DOI: 10.1002/chin.200241169 |
0.381 |
|
| 2010 |
Adams DJ, Blake AJ, Cooke PA, Gill CD, Simpkins NS. ChemInform Abstract: Highly Enantioselective Synthesis of Chiral Imides and Derived Products via Chiral Base Desymmetrization. Cheminform. 33: no-no. DOI: 10.1002/chin.200241034 |
0.34 |
|
| 2010 |
Blake AJ, Cooke PA, Kendall JD, Simpkins NS, Westaway SM. ChemInform Abstract: Concerning the Synthesis and Enantioselective Rearrangements of Episulfoxides. Cheminform. 31: no-no. DOI: 10.1002/chin.200020091 |
0.395 |
|
| 2010 |
Ariffin A, Blake AJ, Ebden MR, Li W, Simpkins NS, Fox DNA. ChemInform Abstract: The Diastereoselective and Enantioselective Substitution Reactions of an Isoindoline-Borane Complex. Cheminform. 31: no-no. DOI: 10.1002/chin.200003028 |
0.337 |
|
| 2010 |
FRIEND CL, SIMPKINS NS, ANSON M, POLYWKA MEC. ChemInform Abstract: Cobalt-Catalyzed Hydro-Sulfenylation of Michael Acceptors. Cheminform. 29: no-no. DOI: 10.1002/chin.199829110 |
0.372 |
|
| 2010 |
ARIFFIN A, BLAKE AJ, LI W, SIMPKINS NS. ChemInform Abstract: Enantioselective Synthesis of Novel Enantiopure Phosphines via Reaction of a Tricarbonyl(η6-arene)chromium Complex with a Chiral Lithium Amide Base. Cheminform. 29: no-no. DOI: 10.1002/chin.199815183 |
0.406 |
|
| 2010 |
BLAKE AJ, WESTAWAY SM, SIMPKINS NS. ChemInform Abstract: The Enantioselective Conversion of Three-Membered Ring Sulfoxides ( Episulfoxides) into Alkenyl Sulfoxides Using Chiral Lithium Amide Bases. Cheminform. 28: no-no. DOI: 10.1002/chin.199751055 |
0.358 |
|
| 2010 |
BROWN CDS, DISHINGTON AP, SHISHKIN O, SIMPKINS NS. ChemInform Abstract: Radical Abstraction vs Cyclization in Reactions of ortho-Bromophenyl Sulfone Systems: Stereoselective Synthesis of Benzo-Fused Six and Seven-Membered Ring Sulfones. Cheminform. 27: no-no. DOI: 10.1002/chin.199602063 |
0.395 |
|
| 2010 |
NEWCOMBE NJ, SIMPKINS NS. ChemInform Abstract: Concise Asymmetric Synthesis of (-)-Anatoxin-a Using an Enantioselective Enolisation Strategy. Cheminform. 26: no-no. DOI: 10.1002/chin.199536251 |
0.373 |
|
| 2010 |
COX PJ, SIMPKINS NS. ChemInform Abstract: An Enantioselective Deprotonation Route to a Versatile Intermediate for C-Nucleoside Synthesis. Cheminform. 23: no-no. DOI: 10.1002/chin.199205271 |
0.337 |
|
| 2010 |
SIMPKINS NS. ChemInform Abstract: New Stereoselective Reactions in Organic Synthesis Cheminform. 22: no-no. DOI: 10.1002/chin.199106359 |
0.345 |
|
| 2010 |
SIMPKINS NS. ChemInform Abstract: The Chemistry of Vinyl Sulfones Cheminform. 22: no-no. DOI: 10.1002/chin.199103358 |
0.346 |
|
| 2009 |
Zhang F, Simpkins NS, Blake AJ. New approaches for the synthesis of erythrinan alkaloids. Organic & Biomolecular Chemistry. 7: 1963-79. PMID 19590794 DOI: 10.1039/B900189A |
0.414 |
|
| 2009 |
Frebault F, Simpkins NS, Fenwick A. Concise enantioselective synthesis of ent-malbrancheamide B. Journal of the American Chemical Society. 131: 4214-5. PMID 19317498 DOI: 10.1021/ja900688y |
0.346 |
|
| 2008 |
Pichowicz M, Simpkins NS, Blake AJ, Wilson C. Studies towards complex bridged alkaloids: regio- and stereocontrolled enolate chemistry of 2,5-diketopiperazines Tetrahedron. 64: 3713-3735. DOI: 10.1016/J.Tet.2008.02.020 |
0.377 |
|
| 2007 |
Ahmad NM, Rodeschini V, Simpkins NS, Ward SE, Blake AJ. Synthesis of polyprenylated acylphloroglucinols using bridgehead lithiation: the total synthesis of racemic clusianone and a formal synthesis of racemic garsubellin A. The Journal of Organic Chemistry. 72: 4803-15. PMID 17530804 DOI: 10.1021/Jo070388H |
0.429 |
|
| 2007 |
Dardennes E, Labano S, Simpkins NS, Wilson C. Michael addition-electrophilic quenching chemistry of maleimides using dialkylzinc reagents Tetrahedron Letters. 48: 6380-6383. DOI: 10.1016/j.tetlet.2007.06.155 |
0.349 |
|
| 2007 |
Pichowicz M, Simpkins NS, Blake AJ, Wilson C. Synthesis Towards Complex Bridged Alkaloids Derived from Diketopiperazines: A Cationic Cascade Approach to Stephacidins, Paraherquamides and Related Systems. Cheminform. 38. DOI: 10.1016/J.Tetlet.2006.09.046 |
0.373 |
|
| 2007 |
Ahmad NM, Rodeschini V, Simpkins NS, Ward SE, Blake AJ. Synthesis of Polyprenylated Acylphloroglucinols Using Bridgehead Lithiation: The Total Synthesis of Racemic Clusianone and a Formal Synthesis of Racemic Garsubellin A. Cheminform. 38. DOI: 10.1002/chin.200748204 |
0.333 |
|
| 2006 |
Rodeschini V, Ahmad NM, Simpkins NS. Synthesis of (+/-)-clusianone: high-yielding bridgehead and diketone substitutions by regioselective lithiation of enol ether derivatives of bicyclo[3.3.1]nonane-2,4,9-triones. Organic Letters. 8: 5283-5. PMID 17078698 DOI: 10.1021/ol0620592 |
0.399 |
|
| 2006 |
Blake AJ, Gill C, Greenhalgh DA, Simpkins NS, Zhang F. An Asymmetric Synthesis of (+)-Erysotramidine. Cheminform. 37. DOI: 10.1002/chin.200618202 |
0.341 |
|
| 2006 |
Baudoux J, Blake AJ, Simpkins NS. Rapid Access to the Welwitindolinone Alkaloid Skeleton by Cyclization of Indolecarboxaldehyde Substituted Cyclohexanones. Cheminform. 37. DOI: 10.1002/chin.200604193 |
0.379 |
|
| 2005 |
Moffat D, Nichols CJ, Riley DA, Simpkins NS. The synthesis of bioactive indolocarbazoles related to K-252a. Organic & Biomolecular Chemistry. 3: 2953-75. PMID 16186927 DOI: 10.1039/b506444a |
0.301 |
|
| 2005 |
Baudoux J, Blake AJ, Simpkins NS. Rapid access to the Welwitindolinone alkaloid skeleton by cyclization of indolecarboxaldehyde substituted cyclohexanones. Organic Letters. 7: 4087-9. PMID 16146358 DOI: 10.1021/ol051239t |
0.379 |
|
| 2005 |
Blake AJ, Gill C, Greenhalgh DA, Simpkins NS, Zhang F. An asymmetric synthesis of (+)-erysotramidine Synthesis. 3287-3292. DOI: 10.1055/S-2005-918478 |
0.373 |
|
| 2004 |
Bennett DJ, Pickering PL, Simpkins NS. A novel asymmetric route to succinimides and derived compounds: synthesis of the lignan lactone (+)-hinokinin. Chemical Communications (Cambridge, England). 1392-3. PMID 15179480 DOI: 10.1039/b403193h |
0.371 |
|
| 2004 |
Huxford T, Simpkins NS. A chiral base desymmetrisation - Ring-closing metathesis route to chiral azaspirocycles: Synthesis of core structures related to pinnaic acid and halichlorine Synlett. 2295-2298. DOI: 10.1055/s-2004-831335 |
0.305 |
|
| 2004 |
Nichols CJ, Simpkins NS. Synthesis of bioactive indolocarbazoles: Synthesis, nucleophilic ring-opening and chiral base desymmetrisation of a cyclic sulfate intermediate Tetrahedron Letters. 45: 7469-7473. DOI: 10.1016/j.tetlet.2004.08.058 |
0.387 |
|
| 2004 |
Bennett DJ, Blake AJ, Cooke PA, Godfrey CRA, Pickering PL, Simpkins NS, Walker MD, Wilson C. Stereoselectivity in reactions of atropisomeric lactams and imides Tetrahedron. 60: 4491-4511. DOI: 10.1016/J.Tet.2004.01.100 |
0.338 |
|
| 2003 |
Giblin GM, Kirk DT, Mitchell L, Simpkins NS. Bridgehead enolates: substitution and asymmetric desymmetrization of small bridged carbonyl compounds by lithium amide bases. Organic Letters. 5: 1673-5. PMID 12735749 DOI: 10.1021/ol034348l |
0.312 |
|
| 2003 |
Simpkins NS, Gill CD. Asymmetric total synthesis of the proposed structure of the medicinal alkaloid jamtine using the chiral base approach. Organic Letters. 5: 535-7. PMID 12583762 DOI: 10.1021/ol027447s |
0.363 |
|
| 2003 |
Gill C, Greenhalgh DA, Simpkins NS. Asymmetric synthesis of the erythrinan alkaloid system using a chiral lithium amide base desymmetrisation as the key step Tetrahedron Letters. 44: 7803-7807. DOI: 10.1016/j.tetlet.2003.08.078 |
0.374 |
|
| 2002 |
Adams DJ, Blake AJ, Cooke PA, Gill CD, Simpkins NS. Highly enantioselective synthesis of chiral imides and derived products via chiral base desymmetrisation Tetrahedron. 58: 4603-4615. DOI: 10.1016/S0040-4020(02)00367-8 |
0.319 |
|
| 2002 |
Beckwith REJ, Heron N, Simpkins NS. Chlorotrimethylsilane-mediated Michael addition reactions of chiral benzylic anions derived from η6-chromiumtricarbonyl complexes Journal of Organometallic Chemistry. 658: 21-33. DOI: 10.1016/S0022-328X(02)01590-5 |
0.329 |
|
| 2001 |
Hutchings M, Moffat D, Simpkins NS. A concise synthesis of fumagillol Synlett. 661-663. |
0.324 |
|
| 2000 |
Ariffin A, Blake A, Li W, Simpkins N. Enantioselective Synthesis of Novel Enantiopure Phosphines via Reaction of a Tricarbonyl(η6-arene)chromium Complex with a Chiral Lithium Amide Base Synlett. 12: 1453-1455. DOI: 10.1055/S-1997-1061 |
0.384 |
|
| 2000 |
Blake AJ, Cooke PA, Kendall JD, Simpkins NS, Westaway SM. Concerning the synthesis and enantioselective rearrangements of episulfoxides Journal of the Chemical Society, Perkin Transactions 1. 153-163. |
0.362 |
|
| 2000 |
Simpkins NS. Enantioselective proton transfer chemistry: Asymmetric synthesis with chiral lithium amide bases Chimia. 54: 53-54. |
0.317 |
|
| 1999 |
Blake AJ, Highton AJ, Majid TN, Simpkins NS. A Very Rapid Stereocontrolled Entry to Highly Functionalized [5-8-5] Ring Systems Using the Saegusa Reaction Organic Letters. 1: 1787-1789. DOI: 10.1021/Ol9902834 |
0.336 |
|
| 1999 |
Hughes AD, Price DA, Simpkins NS. Atropisomeric amides: Stereoselective enolate chemistry and enantioselective synthesis via a new SmI2-mediated reduction Journal of the Chemical Society - Perkin Transactions 1. 1295-1304. |
0.397 |
|
| 1999 |
Ariffin A, Blake AJ, Ebden MR, Li WS, Simpkins NS, Fox DNA. The diastereoselective and enantioselective substitution reactions of an isoindoline-borane complex Journal of the Chemical Society - Perkin Transactions 1. 2439-2447. |
0.305 |
|
| 1999 |
Goldspink NJ, Simpkins NS, Beckmann M. Highly enantioselective synthesis of substituted piperidines using the chiral lithium amide base approach Synlett. 1292-1294. |
0.369 |
|
| 1998 |
Blake AJ, Ebden MR, Fox DNA, Li W, Simpkins NS. Diastereoselective and Enantioselective Substitution Reactions of an Isoindoline-Borane Complex Synlett. 1998: 189-191. DOI: 10.1055/S-1998-1611 |
0.305 |
|
| 1998 |
Jones CD, Simpkins NS, Giblin GMP. Asymmetric synthesis of epibatidine by use of a novel enantioselective sulfinate elimination reaction Tetrahedron Letters. 39: 1023-1024. DOI: 10.1016/S0040-4039(97)10693-1 |
0.362 |
|
| 1998 |
Giblin GMP, Jones CD, Simpkins NS. The total synthesis of the analgesic alkaloid epibatidine Journal of the Chemical Society - Perkin Transactions 1. 3689-3697. |
0.306 |
|
| 1998 |
Adams DJ, Simpkins NS, Smith TJN. New symmetry-breaking deprotonation reactions of cyclic imides using a chiral lithium amide base Chemical Communications. 1605-1606. |
0.331 |
|
| 1998 |
Blake AJ, Ebden MR, Fox DNA, Li WS, Simpkins NS. Diastereoselective and enantioselective substitution reactions of an isoindoline-borane complex Synlett. 189-191. |
0.305 |
|
| 1997 |
Blake A, Westaway S, Simpkins N. The Enantioselective Conversion of Three-Membered Ring Sulfoxides (Episulfoxides) into Alkenyl Sulfoxides using Chiral Lithium Amide Bases Synlett. 1997: 919-920. DOI: 10.1055/S-1997-948 |
0.328 |
|
| 1997 |
Dishington AP, Douthwaite RE, Mortlock A, Muccioli AB, Simpkins NS. Episulfone substitution and ring-opening reactions via α-sulfonyl carbanion intermediates Journal of the Chemical Society - Perkin Transactions 1. 323-337. |
0.31 |
|
| 1997 |
Giblin GMP, Jones CD, Simpkins NS. A concise stereoselective synthesis of epibatidine employing conjugate addition to an alkenyl sulfone intermediate as the key step Synlett. 589-590. |
0.398 |
|
| 1997 |
Simpkins NS. Novel episulfone substitution and ring-opening reactions via α-sulfonyl carbanion intermediates Phosphorus, Sulfur and Silicon and Related Elements. 120: 197-211. |
0.321 |
|
| 1997 |
Ariffin A, Blake AJ, Li WS, Simpkins NS. Enantioselective synthesis of novel enantiopure phosphines via reaction of a tricarbonyl(η6-arene)chromium complex with a chiral lithium amide base Synlett. 1453-1455. |
0.384 |
|
| 1997 |
Blake AJ, Westaway SM, Simpkins NS. The Enantioselective Conversion of Three-Membered Ring Sulfoxides (Episulfoxides) into Alkenyl Sulfoxides using Chiral Lithium Amide Bases Synlett. 1997: 919-920. |
0.328 |
|
| 1996 |
Hughes AD, Price DA, Shishkin O, Simpkins NS. Diastereoselective enolate chemistry using atropisomeric amides Tetrahedron Letters. 37: 7607-7610. DOI: 10.1016/0040-4039(96)01673-5 |
0.376 |
|
| 1996 |
Simpkins NS. Recent advances in asymmetric synthesis using chiral lithium amide bases Pure and Applied Chemistry. 68: 691-694. |
0.333 |
|
| 1996 |
Dishington AP, Muccioli AB, Simpkins NS. Base-Mediated Ring-Opening Reactions of Episulfones to give Alkenylsulfinates: A Stereoselective Synthesis of Alkenyl Sulfones Synlett. 1996: 27-28. |
0.365 |
|
| 1995 |
Brown CDS, Dishington AP, Shishkin O, Simpkins NS. Radical Abstraction vs Cyclisation in Reactions of ortho-Bromophenyl Sulfone Systems: Stereoselective Synthesis of Benz-fused Six and Seven-Membered Ring Sulfones Synlett. 1995: 943-944. DOI: 10.1055/s-1995-5129 |
0.373 |
|
| 1995 |
Newcombe NJ, Simpkins NS. A concise asymmetric synthesis of (-)-anatoxin-a using an enantioselective enolisation strategy Journal of the Chemical Society, Chemical Communications. 831-832. DOI: 10.1039/C39950000831 |
0.337 |
|
| 1994 |
Bambridge K, Begley MJ, Simpkins NS. Simple synthesis of a C2 symmetric vicinal diamine: Highly diastereoselective Grignard addition to a chiral bis-imine Tetrahedron Letters. 35: 3391-3394. DOI: 10.1016/S0040-4039(00)76916-4 |
0.352 |
|
| 1992 |
Simpkins NS, Stokes S, Whittle AJ. An enantiospecific total synthesis of allosamizoline Tetrahedron Letters. 33: 793-796. DOI: 10.1016/S0040-4039(00)77717-3 |
0.302 |
|
| 1992 |
Simpkins NS, Stokes S, Whittle AJ. An enantiospecific synthesis of allosamizoline Journal of the Chemical Society, Perkin Transactions 1. 2471-2477. |
0.322 |
|
| 1991 |
Cox PJ, Simpkins NS. Asymmetric synthesis using homochiral lithium amide bases Tetrahedron: Asymmetry. 2: 1-26. DOI: 10.1016/S0957-4166(00)82150-3 |
0.36 |
|
| 1991 |
Chakraborty R, Simpkins NS. Cyclisation chemistry of some functionalised allylsilanes Tetrahedron. 47: 7689-7698. DOI: 10.1016/S0040-4020(01)88293-4 |
0.311 |
|
| 1990 |
Simpkins NS. Meldola Lecture. New stereoselective reactions in organic synthesis Chemical Society Reviews. 19: 335-354. DOI: 10.1039/CS9901900335 |
0.32 |
|
| 1990 |
Middleton DS, Simpkins NS, J Begley M, K Terrett N. Synthesis of spiroethers using radical cyclisations Tetrahedron. 46: 545-564. DOI: 10.1016/S0040-4020(01)85436-3 |
0.338 |
|
| 1990 |
Cain CM, Cousins RPC, Coumbarides G, Simpkins NS. Asymmetric deprotonation of prochiral ketones using chiral lithium amide bases Tetrahedron. 46: 523-544. DOI: 10.1016/S0040-4020(01)85435-1 |
0.322 |
|
| 1988 |
Simpkins NS. Synthesis of allylic sulphides and selenides by lewis acid mediated displacement reactions of sulphones Tetrahedron Letters. 29: 6787-6790. DOI: 10.1016/S0040-4039(00)82455-7 |
0.311 |
|
| 1988 |
Giblin GMP, Ramcharitar SH, Simpkins NS. Synthesis and stereoselective chemistry of a novel cyclopentadienyl sulphone Tetrahedron Letters. 29: 4197-4200. DOI: 10.1016/S0040-4039(00)80454-2 |
0.376 |
|
| 1988 |
Middleton DS, Simpkins NS, Terrett NK. Facile synthesis of functionalised spiroethers via radical cyclisations Tetrahedron Letters. 29: 1315-1318. DOI: 10.1016/S0040-4039(00)80286-5 |
0.32 |
|
| 1986 |
Jones PS, Ley SV, Simpkins NS, Whittle AJ. Total synthesis of the insect antifeedant ajugarin I and degradation studies of related clerodane diterpenes Tetrahedron. 42: 6519-6534. DOI: 10.1016/S0040-4020(01)88114-X |
0.468 |
|
| 1985 |
Craig D, Ley SV, Simpkins NS, Whitham GH, Prior MJ. Preparation of vinylic sulphones by Peterson olefination using phenyl trimethylsilylmethyl sulphone Journal of the Chemical Society, Perkin Transactions 1. 1949-1952. DOI: 10.1039/P19850001949 |
0.502 |
|
| 1985 |
CRAIG D, LEY SV, SIMPKINS NS, WHITHAM GH, PRIOR MJ. ChemInform Abstract: PREPARATION OF VINYLIC SULFONES BY PETERSON OLEFINATION USING PHENYL TRIMETHYLSILYLMETHYL SULFONE Chemischer Informationsdienst. 16. DOI: 10.1002/chin.198552191 |
0.474 |
|
| 1984 |
LEY SV, SIMPKINS NS. ChemInform Abstract: PETERSON OLEFINATION USING PHENYLSULFONYLTRIMETHYLSILYLMETHANE. A NEW PREPARATION OF VINYLIC SULFONES Chemischer Informationsdienst. 15. DOI: 10.1002/Chin.198412172 |
0.43 |
|
| 1983 |
Ley SV, Simpkins NS. Peterson olefination using phenylsulphonyltrimethylsilylmethane. A new preparation of vinylic sulphones Journal of the Chemical Society, Chemical Communications. 1281-1282. |
0.305 |
|
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