Lakshmi A Devi - Publications

Affiliations: 
pharmacological sciences Icahn School of Medicine at Mount Sinai, New York, NY, United States 

180 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Duarte ML, Wang M, Gomes I, Liu C, Sharma A, Fakira AK, Gupta A, Mack SM, Zhang B, Devi LA. . Molecular Pharmacology. PMID 37147110 DOI: 10.1124/molpharm.122.000641  0.774
2022 Sakloth F, Sanchez Reyes OB, Ruiz A, Nicolais A, Serafini RA, Pryce KD, Bertherat F, Torres Berrio A, Gomes I, Devi LA, Wacker D, Zachariou V. . Molecular Pharmacology. PMID 36310031 DOI: 10.1124/molpharm.122.000528  0.339
2022 Fricker LD, Lemos Duarte M, Jeltyi A, Lueptow L, Fakira AK, Tashima AK, Hochgeschwender U, Wetsel WC, Devi LA. Mice heterozygous for a null mutation of CPE show reduced expression of carboxypeptidase e mRNA and enzyme activity but normal physiology, behavior, and levels of neuropeptides. Brain Research. 1789: 147951. PMID 35618016 DOI: 10.1016/j.brainres.2022.147951  0.768
2022 Mack SM, Gomes I, Fakira AK, Duarte ML, Gupta A, Fricker L, Devi LA. . Molecular Pharmacology. PMID 35605991 DOI: 10.1124/molpharm.122.000487  0.789
2021 Fakira AK, Lueptow LM, Trimbake NA, Devi LA. PEN Receptor GPR83 in Anxiety-Like Behaviors: Differential Regulation in Global vs Amygdalar Knockdown. Frontiers in Neuroscience. 15: 675769. PMID 34512237 DOI: 10.3389/fnins.2021.675769  0.779
2021 Kunselman JM, Gupta A, Gomes I, Devi LA, Puthenveedu MA. Compartment-specific opioid receptor signaling is selectively modulated by different Dynorphin peptides. Elife. 10. PMID 33908346 DOI: 10.7554/eLife.60270  0.403
2021 Rae M, Duarte ML, Gomes I, Camarini R, Devi LA. Oxytocin and vasopressin: Signalling, behavioural modulation and potential therapeutic effects. British Journal of Pharmacology. PMID 33817785 DOI: 10.1111/bph.15481  0.329
2021 Gupta A, Gullapalli S, Pan H, Ramos-Ortolaza DL, Hayward MD, Low MJ, Pintar JE, Devi LA, Gomes I. Regulation of Opioid Receptors by Their Endogenous Opioid Peptides. Cellular and Molecular Neurobiology. PMID 33389463 DOI: 10.1007/s10571-020-01015-w  0.386
2020 Fricker LD, Tashima AK, Fakira AK, Hochgeschwender U, Wetsel WC, Devi LA. Neuropeptidomic Analysis of a Genetically Defined Cell Type in Mouse Brain and Pituitary. Cell Chemical Biology. PMID 33217339 DOI: 10.1016/j.chembiol.2020.11.003  0.775
2020 Fakira AK, Devi LA, Kennedy PJ. Novel Application for G Protein-Biased Mu Opioid Receptor Agonists in Opioid Relapse Prevention. Biological Psychiatry. 88: 896-897. PMID 33213702 DOI: 10.1016/j.biopsych.2020.09.006  0.805
2020 Faouzi A, Uprety R, Gomes I, Massaly N, Keresztes AI, Le Rouzic V, Gupta A, Zhang T, Yoon HJ, Ansonoff M, Allaoa A, Pan YX, Pintar J, Morón JA, Streicher JM, ... Devi LA, et al. Synthesis and Pharmacology of a Novel μ-δ Opioid Receptor Heteromer-Selective Agonist Based on the Carfentanyl Template. Journal of Medicinal Chemistry. PMID 33170687 DOI: 10.1021/acs.jmedchem.0c00901  0.799
2020 Palma JA, Gupta A, Sierra S, Gomes I, Balgobin B, Norcliffe-Kaufmann L, Devi LA, Kaufmann H. Autoantibodies blocking M muscarinic receptors cause postganglionic cholinergic dysautonomia. Annals of Neurology. PMID 32833276 DOI: 10.1002/Ana.25882  0.349
2020 Fricker LD, Margolis E, Gomes I, Devi LA. Five decades of research on opioid peptides: Current knowledge and unanswered questions. Molecular Pharmacology. PMID 32487735 DOI: 10.1124/Mol.120.119388  0.469
2020 Lemos Duarte M, Devi LA. Post-translational Modifications of Opioid Receptors. Trends in Neurosciences. 43: 417-432. PMID 32459993 DOI: 10.1016/J.Tins.2020.03.011  0.512
2020 Gomes I, Sierra S, Lueptow L, Gupta A, Gouty S, Margolis EB, Cox BM, Devi LA. Biased signaling by endogenous opioid peptides. Proceedings of the National Academy of Sciences of the United States of America. PMID 32393639 DOI: 10.1073/Pnas.2000712117  0.507
2020 Sakloth F, Singh M, Serafini R, Gomes I, Devi L, Zachariou V. RGSz1 actions in the periaqueductal gray modulate opioid reward and analgesic tolerance The Faseb Journal. 34: 1-1. DOI: 10.1096/Fasebj.2020.34.S1.03381  0.368
2019 Tiwari V, He SQ, Huang Q, Liang L, Yang F, Chen Z, Tiwari V, Fujita W, Devi LA, Dong X, Guan Y, Raja SN. Activation of µ-δ opioid receptor heteromers inhibits neuropathic pain behavior in rodents. Pain. PMID 31815916 DOI: 10.1097/J.Pain.0000000000001768  0.394
2019 Sierra S, Gupta A, Gomes I, Fowkes M, Ram A, Bobeck EN, Devi LA. Targeting Cannabinoid 1 and Delta Opioid Receptor Heteromers Alleviates Chemotherapy-Induced Neuropathic Pain. Acs Pharmacology & Translational Science. 2: 219-229. PMID 31565698 DOI: 10.1021/acsptsci.9b00008  0.306
2019 McDermott MV, Afrose L, Gomes I, Devi LA, Bobeck EN. Opioid-induced signaling and antinociception are modulated by the recently deorphanized receptor, GPR171. The Journal of Pharmacology and Experimental Therapeutics. PMID 31308196 DOI: 10.1124/Jpet.119.259242  0.516
2019 Fakira AK, Peck EG, Liu Y, Lueptow LM, Trimbake NA, Han MH, Calipari ES, Devi LA. The role of the neuropeptide PEN receptor, GPR83, in the reward pathway: Relationship to sex-differences. Neuropharmacology. 107666. PMID 31199956 DOI: 10.1016/J.Neuropharm.2019.107666  0.778
2019 Mack SM, Gomes I, Devi LA. Neuropeptide PEN and its receptor GPR83; Distribution, Signaling and Regulation. Acs Chemical Neuroscience. PMID 30726666 DOI: 10.1021/Acschemneuro.8B00559  0.449
2019 Borsodi A, Bruchas M, Caló G, Chavkin C, Christie MJ, Civelli O, Connor M, Cox BM, Devi LA, Evans C, Höllt V, Henderson G, Husbands S, Kelly E, Kieffer B, et al. Opioid receptors (version 2019.4) in the IUPHAR/BPS Guide to Pharmacology Database Iuphar/Bps Guide to Pharmacology Cite. 2019. DOI: 10.2218/gtopdb/f50/2019.4  0.362
2018 Majumdar S, Devi LA. Strategy for making safer opioids bolstered. Nature. 553: 286-288. PMID 32076275 DOI: 10.1038/D41586-018-00045-1  0.448
2018 Fujita W, Yokote M, Gomes I, Gupta A, Ueda H, Devi LA. Regulation of a opioid receptor chaperone protein, RTP4, by morphine. Molecular Pharmacology. PMID 30348895 DOI: 10.1124/Mol.118.112987  0.504
2018 Lueptow LM, Devi LA, Fakira AK. Targeting the Recently Deorphanized Receptor GPR83 for the Treatment of Immunological, Neuroendocrine and Neuropsychiatric Disorders. Progress in Molecular Biology and Translational Science. 159: 1-25. PMID 30340784 DOI: 10.1016/Bs.Pmbts.2018.07.002  0.804
2018 Pena DA, Duarte ML, Pramio DT, Devi LA, Schechtman D. Exploring Morphine-Triggered PKC-Targets and Their Interaction with Signaling Pathways Leading to Pain via TrkA. Proteomes. 6. PMID 30301203 DOI: 10.3390/Proteomes6040039  0.492
2018 Heimann AS, Gupta A, Gomes I, Rahman R, Schlessinger A, Ferro ES, Unterwald EM, Devi LA. Correction: Generation of G protein-coupled receptor antibodies differentially sensitive to conformational states. Plos One. 13: e0193322. PMID 29447277 DOI: 10.1371/Journal.Pone.0193322  0.326
2017 Fricker LD, Devi LA. Orphan neuropeptides and receptors: Novel therapeutic targets. Pharmacology & Therapeutics. PMID 29174650 DOI: 10.1016/J.Pharmthera.2017.11.006  0.477
2017 Reckziegel P, Festuccia WT, Britto LRG, Jang KLL, Romão CM, Heimann JC, Fogaça MV, Rodrigues NS, Silva NR, Guimarães FS, Eichler RAS, Gupta A, Gomes I, Devi LA, Heimann AS, et al. A novel peptide that improves metabolic parameters without adverse central nervous system effects. Scientific Reports. 7: 14781. PMID 29093454 DOI: 10.1038/S41598-017-13690-9  0.457
2017 Heimann AS, Gupta A, Gomes I, Rayees R, Schlessinger A, Ferro ES, Unterwald EM, Devi LA. Generation of G protein-coupled receptor antibodies differentially sensitive to conformational states. Plos One. 12: e0187306. PMID 29091950 DOI: 10.1371/journal.pone.0187306  0.3
2017 Margolis EB, Fujita W, Devi LA, Fields HL. Two delta opioid receptor subtypes are functional in single ventral tegmental area neurons, and can interact with the mu opioid receptor. Neuropharmacology. PMID 28645621 DOI: 10.1016/J.Neuropharm.2017.06.019  0.419
2017 Bobeck EN, Gomes I, Pena D, Cummings KA, Clem RL, Mezei M, Devi LA. The BigLEN-GPR171 Peptide Receptor System within the Basolateral Amygdala Regulates Anxiety-Like Behavior and Contextual Fear Conditioning. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 28425495 DOI: 10.1038/Npp.2017.79  0.358
2016 Gomes I, Sierra S, Devi LA. Detection of Receptor Heteromerization Using In Situ Proximity Ligation Assay. Current Protocols in Pharmacology. 75: 2.16.1-2.16.31. PMID 27960030 DOI: 10.1002/Cpph.15  0.435
2016 Wardman JH, Gomes I, Bobeck EN, Stockert JA, Kapoor A, Bisignano P, Gupta A, Mezei M, Kumar S, Filizola M, Devi LA. Identification of a small-molecule ligand that activates the neuropeptide receptor GPR171 and increases food intake. Science Signaling. 9: ra55. PMID 27245612 DOI: 10.1126/Scisignal.Aac8035  0.384
2016 Gupta A, Gomes I, Bobeck EN, Fakira AK, Massaro NP, Sharma I, Cavé A, Hamm HE, Parello J, Devi LA. Collybolide is a novel biased agonist of κ-opioid receptors with potent antipruritic activity. Proceedings of the National Academy of Sciences of the United States of America. PMID 27162327 DOI: 10.1073/Pnas.1521825113  0.81
2016 Gomes I, Bobeck EN, Margolis EB, Gupta A, Sierra S, Fakira AK, Fujita W, Müller TD, Müller A, Tschöp MH, Kleinau G, Fricker LD, Devi LA. Identification of GPR83 as the receptor for the neuroendocrine peptide PEN. Science Signaling. 9: ra43. PMID 27117253 DOI: 10.1126/Scisignal.Aad0694  0.81
2016 Pena DA, Andrade VP, Silva GÁ, Neves JI, Oliveira PS, Alves MJ, Devi LA, Schechtman D. Rational design and validation of an anti-protein kinase C active-state specific antibody based on conformational changes. Scientific Reports. 6: 22114. PMID 26911897 DOI: 10.1038/Srep22114  0.326
2016 Gomes I, Ayoub MA, Fujita W, Jaeger WC, Pfleger KD, Devi LA. G Protein-Coupled Receptor Heteromers. Annual Review of Pharmacology and Toxicology. 56: 403-25. PMID 26514203 DOI: 10.1146/Annurev-Pharmtox-011613-135952  0.444
2015 Stockton SD, Gomes I, Liu T, Moraje C, Hipólito L, Jones MR, Ma'ayan A, Morón JA, Li H, Devi LA. Morphine Regulated Synaptic Networks Revealed by Integrated Proteomics and Network Analysis. Molecular & Cellular Proteomics : McP. PMID 26149443 DOI: 10.1074/Mcp.M115.047977  0.799
2015 Stockert JA, Devi LA. Advancements in therapeutically targeting orphan GPCRs. Frontiers in Pharmacology. 6: 100. PMID 26005419 DOI: 10.3389/Fphar.2015.00100  0.408
2015 Fujita W, Gomes I, Devi LA. Heteromers of μ-δ opioid receptors: new pharmacology and novel therapeutic possibilities. British Journal of Pharmacology. 172: 375-87. PMID 24571499 DOI: 10.1111/Bph.12663  0.519
2015 Cox BM, Christie MJ, Devi L, Toll L, Traynor JR. Challenges for opioid receptor nomenclature: IUPHAR Review 9. British Journal of Pharmacology. 172: 317-23. PMID 24528283 DOI: 10.1111/Bph.12612  0.492
2015 Gupta A, Fujita W, Gomes I, Bobeck E, Devi LA. Endothelin-converting enzyme 2 differentially regulates opioid receptor activity British Journal of Pharmacology. 172: 704-719. DOI: 10.1111/Bph.12833  0.518
2014 Gomes I, Gupta A, Bushlin I, Devi LA. Antibodies to probe endogenous G protein-coupled receptor heteromer expression, regulation, and function. Frontiers in Pharmacology. 5: 268. PMID 25520661 DOI: 10.3389/Fphar.2014.00268  0.462
2014 Fujita W, Gomes I, Dove LS, Prohaska D, McIntyre G, Devi LA. Molecular characterization of eluxadoline as a potential ligand targeting mu-delta opioid receptor heteromers. Biochemical Pharmacology. 92: 448-56. PMID 25261794 DOI: 10.1016/J.Bcp.2014.09.015  0.491
2014 Kivell B, Uzelac Z, Sundaramurthy S, Rajamanickam J, Ewald A, Chefer V, Jaligam V, Bolan E, Simonson B, Annamalai B, Mannangatti P, Prisinzano TE, Gomes I, Devi LA, Jayanthi LD, et al. Salvinorin A regulates dopamine transporter function via a kappa opioid receptor and ERK1/2-dependent mechanism. Neuropharmacology. 86: 228-40. PMID 25107591 DOI: 10.1016/J.Neuropharm.2014.07.016  0.591
2014 Fujita W, Gomes I, Devi LA. Revolution in GPCR signalling: opioid receptor heteromers as novel therapeutic targets: IUPHAR review 10. British Journal of Pharmacology. 171: 4155-76. PMID 24916280 DOI: 10.1111/Bph.12798  0.512
2014 Gupta A, Gomes I, Wardman J, Devi LA. Opioid receptor function is regulated by post-endocytic peptide processing. The Journal of Biological Chemistry. 289: 19613-26. PMID 24847082 DOI: 10.1074/Jbc.M113.537704  0.504
2014 Toniolo EF, Maique ET, Ferreira WA, Heimann AS, Ferro ES, Ramos-Ortolaza DL, Miller L, Devi LA, Dale CS. Hemopressin, an inverse agonist of cannabinoid receptors, inhibits neuropathic pain in rats. Peptides. 56: 125-31. PMID 24703998 DOI: 10.1016/J.Peptides.2014.03.016  0.392
2014 Ferré S, Casadó V, Devi LA, Filizola M, Jockers R, Lohse MJ, Milligan G, Pin JP, Guitart X. G protein-coupled receptor oligomerization revisited: functional and pharmacological perspectives. Pharmacological Reviews. 66: 413-34. PMID 24515647 DOI: 10.1124/Pr.113.008052  0.419
2014 Matsumoto K, Narita M, Muramatsu N, Nakayama T, Misawa K, Kitajima M, Tashima K, Devi LA, Suzuki T, Takayama H, Horie S. Orally Active opioid μ/δ dual agonist MGM-16, a derivative of the indole alkaloid mitragynine, exhibits potent antiallodynic effect on neuropathic pain in mices Journal of Pharmacology and Experimental Therapeutics. 348: 383-392. PMID 24345467 DOI: 10.1124/Jpet.113.208108  0.404
2014 Stockton SD, Devi LA. An integrated quantitative proteomics and systems biology approach to explore synaptic protein profile changes during morphine exposure. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 39: 88-103. PMID 24045585 DOI: 10.1038/Npp.2013.227  0.793
2013 Gomes I, Aryal DK, Wardman JH, Gupta A, Gagnidze K, Rodriguiz RM, Kumar S, Wetsel WC, Pintar JE, Fricker LD, Devi LA. GPR171 is a hypothalamic G protein-coupled receptor for BigLEN, a neuropeptide involved in feeding. Proceedings of the National Academy of Sciences of the United States of America. 110: 16211-6. PMID 24043826 DOI: 10.1073/Pnas.1312938110  0.776
2013 Gomes I, Fujita W, Gupta A, Saldanha SA, Saldanha AS, Negri A, Pinello CE, Eberhart C, Roberts E, Filizola M, Hodder P, Devi LA. Identification of a μ-δ opioid receptor heteromer-biased agonist with antinociceptive activity. Proceedings of the National Academy of Sciences of the United States of America. 110: 12072-7. PMID 23818586 DOI: 10.1073/Pnas.1222044110  0.524
2013 Gomes I, Fujita W, Chandrakala MV, Devi LA. Disease-specific heteromerization of G-protein-coupled receptors that target drugs of abuse. Progress in Molecular Biology and Translational Science. 117: 207-65. PMID 23663971 DOI: 10.1016/B978-0-12-386931-9.00009-X  0.496
2013 Gomes I, Gupta A, Devi LA. G-protein-coupled heteromers: regulation in disease. Methods in Enzymology. 521: 219-38. PMID 23351742 DOI: 10.1016/B978-0-12-391862-8.00012-0  0.472
2013 Filizola M, Devi LA. Grand opening of structure-guided design for novel opioids. Trends in Pharmacological Sciences. 34: 6-12. PMID 23127545 DOI: 10.1016/J.Tips.2012.10.002  0.422
2013 Narita M, Imai S, Nakamura A, Ozeki A, Asato M, Rahmadi M, Sudo Y, Hojo M, Uezono Y, Devi LA, Kuzumaki N, Suzuki T. Possible involvement of prolonging spinal μ-opioid receptor desensitization in the development of antihyperalgesic tolerance to μ-opioids under a neuropathic pain-like state Addiction Biology. 18: 614-622. PMID 21812868 DOI: 10.1111/J.1369-1600.2011.00354.X  0.407
2012 Bushlin I, Gupta A, Stockton SD, Miller LK, Devi LA. Dimerization with cannabinoid receptors allosterically modulates delta opioid receptor activity during neuropathic pain. Plos One. 7: e49789. PMID 23272051 DOI: 10.1371/Journal.Pone.0049789  0.814
2012 Filizola M, Devi LA. Structural biology: How opioid drugs bind to receptors. Nature. 485: 314-7. PMID 22596150 DOI: 10.1038/485314A  0.467
2012 Costantino CM, Gomes I, Stockton SD, Lim MP, Devi LA. Opioid receptor heteromers in analgesia. Expert Reviews in Molecular Medicine. 14: e9. PMID 22490239 DOI: 10.1017/Erm.2012.5  0.82
2012 Costantino CM, Gupta A, Yewdall AW, Dale BM, Devi LA, Chen BK. Cannabinoid receptor 2-mediated attenuation of CXCR4-tropic HIV infection in primary CD4+ T cells. Plos One. 7: e33961. PMID 22448282 DOI: 10.1371/Journal.Pone.0033961  0.337
2012 Rozenfeld R, Bushlin I, Gomes I, Tzavaras N, Gupta A, Neves S, Battini L, Gusella GL, Lachmann A, Ma'ayan A, Blitzer RD, Devi LA. Receptor heteromerization expands the repertoire of cannabinoid signaling in rodent neurons. Plos One. 7: e29239. PMID 22235275 DOI: 10.1371/Journal.Pone.0029239  0.428
2012 Stockton SD, Devi LA. Functional relevance of μ-δ opioid receptor heteromerization: a role in novel signaling and implications for the treatment of addiction disorders: from a symposium on new concepts in mu-opioid pharmacology. Drug and Alcohol Dependence. 121: 167-72. PMID 22115888 DOI: 10.1016/J.Drugalcdep.2011.10.025  0.812
2012 Berg KA, Rowan MP, Gupta A, Sanchez TA, Silva M, Gomes I, McGuire BA, Portoghese PS, Hargreaves KM, Devi LA, Clarke WP. Allosteric interactions between δ and κ opioid receptors in peripheral sensory neurons. Molecular Pharmacology. 81: 264-72. PMID 22072818 DOI: 10.1124/Mol.111.072702  0.426
2011 Abul-Husn NS, Annangudi SP, Ma'ayan A, Ramos-Ortolaza DL, Stockton SD, Gomes I, Sweedler JV, Devi LA. Chronic morphine alters the presynaptic protein profile: identification of novel molecular targets using proteomics and network analysis. Plos One. 6: e25535. PMID 22043286 DOI: 10.1371/Journal.Pone.0025535  0.787
2011 Miller LK, Hou X, Rodriguiz RM, Gagnidze K, Sweedler JV, Wetsel WC, Devi LA. Mice deficient in endothelin-converting enzyme-2 exhibit abnormal responses to morphine and altered peptide levels in the spinal cord. Journal of Neurochemistry. 119: 1074-85. PMID 21972895 DOI: 10.1111/J.1471-4159.2011.07513.X  0.742
2011 Miller LK, Devi LA. The highs and lows of cannabinoid receptor expression in disease: mechanisms and their therapeutic implications. Pharmacological Reviews. 63: 461-70. PMID 21752875 DOI: 10.1124/Pr.110.003491  0.418
2011 Gupta A, Devi LA, Gomes I. Potentiation of μ-opioid receptor-mediated signaling by ketamine. Journal of Neurochemistry. 119: 294-302. PMID 21692801 DOI: 10.1111/J.1471-4159.2011.07361.X  0.471
2011 Rozenfeld R, Gupta A, Gagnidze K, Lim MP, Gomes I, Lee-Ramos D, Nieto N, Devi LA. AT1R-CB₁R heteromerization reveals a new mechanism for the pathogenic properties of angiotensin II. The Embo Journal. 30: 2350-63. PMID 21540834 DOI: 10.1038/Emboj.2011.139  0.755
2011 Imai S, Sudo Y, Nakamura A, Ozeki A, Asato M, Hojo M, Devi LA, Kuzumaki N, Suzuki T, Uezono Y, Narita M. Possible involvement of β-endorphin in a loss of the coordinated balance of μ-opioid receptors trafficking processes by fentanyl. Synapse (New York, N.Y.). 65: 962-6. PMID 21437993 DOI: 10.1002/Syn.20930  0.41
2011 Gomes I, Ijzerman AP, Ye K, Maillet EL, Devi LA. G protein-coupled receptor heteromerization: a role in allosteric modulation of ligand binding. Molecular Pharmacology. 79: 1044-52. PMID 21415307 DOI: 10.1124/Mol.110.070847  0.446
2011 Golebiewska U, Johnston JM, Devi L, Filizola M, Scarlata S. Differential response to morphine of the oligomeric state of μ-opioid in the presence of δ-opioid receptors. Biochemistry. 50: 2829-37. PMID 21361347 DOI: 10.1021/Bi101701X  0.46
2011 Rozenfeld R, Devi LA. Exploring a role for heteromerization in GPCR signalling specificity. The Biochemical Journal. 433: 11-8. PMID 21158738 DOI: 10.1042/Bj20100458  0.451
2010 Ouimet T, Orng SV, Poras H, Gagnidze K, Devi LA, Fournié-Zaluski MC, Roques BP. Identification of an endothelin-converting enzyme-2-specific fluorigenic substrate and development of an in vitro and ex vivo enzymatic assay. The Journal of Biological Chemistry. 285: 34390-400. PMID 20807771 DOI: 10.1074/Jbc.M110.120576  0.713
2010 LaRocca TJ, Schwarzkopf M, Altman P, Zhang S, Gupta A, Gomes I, Alvin Z, Champion HC, Haddad G, Hajjar RJ, Devi LA, Schecter AD, Tarzami ST. β2-Adrenergic receptor signaling in the cardiac myocyte is modulated by interactions with CXCR4. Journal of Cardiovascular Pharmacology. 56: 548-59. PMID 20729750 DOI: 10.1097/Fjc.0B013E3181F713Fe  0.401
2010 Williams D, Devi LA. Escorts take the lead molecular chaperones as therapeutic targets. Progress in Molecular Biology and Translational Science. 91: 121-49. PMID 20691961 DOI: 10.1016/S1877-1173(10)91005-3  0.445
2010 Hipser C, Bushlin I, Gupta A, Gomes I, Devi LA. Role of antibodies in developing drugs that target G-protein-coupled receptor dimers. The Mount Sinai Journal of Medicine, New York. 77: 374-80. PMID 20687183 DOI: 10.1002/Msj.20199  0.425
2010 Gupta A, Mulder J, Gomes I, Rozenfeld R, Bushlin I, Ong E, Lim M, Maillet E, Junek M, Cahill CM, Harkany T, Devi LA. Increased abundance of opioid receptor heteromers after chronic morphine administration. Science Signaling. 3: ra54. PMID 20647592 DOI: 10.1126/Scisignal.2000807  0.458
2010 Khelashvili G, Dorff K, Shan J, Camacho-Artacho M, Skrabanek L, Vroling B, Bouvier M, Devi LA, George SR, Javitch JA, Lohse MJ, Milligan G, Neubig RR, Palczewski K, Parmentier M, et al. GPCR-OKB: the G Protein Coupled Receptor Oligomer Knowledge Base. Bioinformatics (Oxford, England). 26: 1804-5. PMID 20501551 DOI: 10.1093/Bioinformatics/Btq264  0.372
2010 Morgan DJ, Wei S, Gomes I, Czyzyk T, Mzhavia N, Pan H, Devi LA, Fricker LD, Pintar JE. The propeptide precursor proSAAS is involved in fetal neuropeptide processing and body weight regulation. Journal of Neurochemistry. 113: 1275-84. PMID 20367757 DOI: 10.1111/J.1471-4159.2010.06706.X  0.332
2010 Rozenfeld R, Devi LA. Receptor heteromerization and drug discovery. Trends in Pharmacological Sciences. 31: 124-30. PMID 20060175 DOI: 10.1016/J.Tips.2009.11.008  0.457
2010 Ramos-Ortolaza DL, Bushlin I, Abul-Husn N, Annangudi SP, Sweedler J, Devi LA. Quantitative neuroproteomics of the synapse. Methods in Molecular Biology (Clifton, N.J.). 615: 227-46. PMID 20013213 DOI: 10.1007/978-1-60761-535-4_18  0.63
2010 Morón JA, Gullapalli S, Taylor C, Gupta A, Gomes I, Devi LA. Modulation of opiate-related signaling molecules in morphine-dependent conditioned behavior: conditioned place preference to morphine induces CREB phosphorylation. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 35: 955-66. PMID 19956087 DOI: 10.1038/Npp.2009.199  0.433
2010 Bushlin I, Rozenfeld R, Devi LA. Cannabinoid-opioid interactions during neuropathic pain and analgesia. Current Opinion in Pharmacology. 10: 80-6. PMID 19857996 DOI: 10.1016/J.Coph.2009.09.009  0.48
2009 Miller J, Agarwal A, Devi LA, Fontanini K, Hamilton JA, Pin JP, Shields DC, Spek CA, Sakmar TP, Kuliopulos A, Hunt SW. Insider access: pepducin symposium explores a new approach to GPCR modulation. Annals of the New York Academy of Sciences. 1180: E1-12. PMID 19925639 DOI: 10.1111/J.1749-6632.2009.05326.X  0.42
2009 Abul-Husn NS, Bushlin I, Morón JA, Jenkins SL, Dolios G, Wang R, Iyengar R, Ma'ayan A, Devi LA. Systems approach to explore components and interactions in the presynapse. Proteomics. 9: 3303-15. PMID 19562802 DOI: 10.1002/Pmic.200800767  0.629
2009 Gomes I, Grushko JS, Golebiewska U, Hoogendoorn S, Gupta A, Heimann AS, Ferro ES, Scarlata S, Fricker LD, Devi LA. Novel endogenous peptide agonists of cannabinoid receptors. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 23: 3020-9. PMID 19380512 DOI: 10.1096/Fj.09-132142  0.443
2009 Alfaras-Melainis K, Gomes I, Rozenfeld R, Zachariou V, Devi L. Modulation of opioid receptor function by protein-protein interactions. Frontiers in Bioscience (Landmark Edition). 14: 3594-607. PMID 19273296 DOI: 10.2735/3474  0.416
2009 Ferré S, Baler R, Bouvier M, Caron MG, Devi LA, Durroux T, Fuxe K, George SR, Javitch JA, Lohse MJ, Mackie K, Milligan G, Pfleger KD, Pin JP, Volkow ND, et al. Building a new conceptual framework for receptor heteromers. Nature Chemical Biology. 5: 131-4. PMID 19219011 DOI: 10.1038/Nchembio0309-131  0.363
2008 Décaillot FM, Rozenfeld R, Gupta A, Devi LA. Cell surface targeting of mu-delta opioid receptor heterodimers by RTP4. Proceedings of the National Academy of Sciences of the United States of America. 105: 16045-50. PMID 18836069 DOI: 10.1073/Pnas.0804106105  0.51
2008 Ellgren M, Artmann A, Tkalych O, Gupta A, Hansen HS, Hansen SH, Devi LA, Hurd YL. Dynamic changes of the endogenous cannabinoid and opioid mesocorticolimbic systems during adolescence: THC effects. European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology. 18: 826-34. PMID 18674887 DOI: 10.1016/J.Euroneuro.2008.06.009  0.313
2008 Gupta A, Heimann AS, Gomes I, Devi LA. Antibodies against G-protein coupled receptors: novel uses in screening and drug development. Combinatorial Chemistry & High Throughput Screening. 11: 463-7. PMID 18673273 DOI: 10.2174/138620708784911465  0.324
2008 Gagnidze K, Sachchidanand, Rozenfeld R, Mezei M, Zhou MM, Devi LA. Homology modeling and site-directed mutagenesis to identify selective inhibitors of endothelin-converting enzyme-2. Journal of Medicinal Chemistry. 51: 3378-87. PMID 18507370 DOI: 10.1021/Jm7015478  0.708
2008 Charlton JJ, Allen PB, Psifogeorgou K, Chakravarty S, Gomes I, Neve RL, Devi LA, Greengard P, Nestler EJ, Zachariou V. Multiple actions of spinophilin regulate mu opioid receptor function. Neuron. 58: 238-47. PMID 18439408 DOI: 10.1016/J.Neuron.2008.02.006  0.484
2008 Rozenfeld R, Devi LA. Regulation of CB1 cannabinoid receptor trafficking by the adaptor protein AP-3. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 22: 2311-22. PMID 18267983 DOI: 10.1096/Fj.07-102731  0.446
2008 Gupta A, Rozenfeld R, Gomes I, Raehal KM, Décaillot FM, Bohn LM, Devi LA. Post-activation-mediated changes in opioid receptors detected by N-terminal antibodies. The Journal of Biological Chemistry. 283: 10735-44. PMID 18256033 DOI: 10.1074/Jbc.M709454200  0.4
2008 Devi L, Petanceska S, Liu R, Arbabha B, Bansinath M, Garg U. Regulation of neuropeptide-processing enzymes by nitric oxide in cultured astrocytes. Journal of Neurochemistry. 62: 2387-2393. PMID 8189243 DOI: 10.1046/J.1471-4159.1994.62062387.X  0.316
2007 Heimann AS, Gomes I, Dale CS, Pagano RL, Gupta A, de Souza LL, Luchessi AD, Castro LM, Giorgi R, Rioli V, Ferro ES, Devi LA. Hemopressin is an inverse agonist of CB1 cannabinoid receptors. Proceedings of the National Academy of Sciences of the United States of America. 104: 20588-93. PMID 18077343 DOI: 10.1073/Pnas.0706980105  0.478
2007 Rozenfeld R, Abul-Husn NS, Gomez I, Devi LA. An emerging role for the delta opioid receptor in the regulation of mu opioid receptor function. Thescientificworldjournal. 7: 64-73. PMID 17982578 DOI: 10.1100/Tsw.2007.219  0.714
2007 Skrabanek L, Murcia M, Bouvier M, Devi L, George SR, Lohse MJ, Milligan G, Neubig R, Palczewski K, Parmentier M, Pin JP, Vriend G, Javitch JA, Campagne F, Filizola M. Requirements and ontology for a G protein-coupled receptor oligomerization knowledge base. Bmc Bioinformatics. 8: 177. PMID 17537266 DOI: 10.1186/1471-2105-8-177  0.341
2007 Morón JA, Devi LA. Use of proteomics for the identification of novel drug targets in brain diseases. Journal of Neurochemistry. 102: 306-15. PMID 17419802 DOI: 10.1111/J.1471-4159.2007.04536.X  0.305
2007 Rozenfeld R, Devi LA. Receptor heterodimerization leads to a switch in signaling: beta-arrestin2-mediated ERK activation by mu-delta opioid receptor heterodimers. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 21: 2455-65. PMID 17384143 DOI: 10.1096/Fj.06-7793Com  0.426
2007 Pin JP, Neubig R, Bouvier M, Devi L, Filizola M, Javitch JA, Lohse MJ, Milligan G, Palczewski K, Parmentier M, Spedding M. International Union of Basic and Clinical Pharmacology. LXVII. Recommendations for the recognition and nomenclature of G protein-coupled receptor heteromultimers. Pharmacological Reviews. 59: 5-13. PMID 17329545 DOI: 10.1124/Pr.59.1.5  0.413
2007 Bolan EA, Kivell B, Jaligam V, Oz M, Jayanthi LD, Han Y, Sen N, Urizar E, Gomes I, Devi LA, Ramamoorthy S, Javitch JA, Zapata A, Shippenberg TS. D2 receptors regulate dopamine transporter function via an extracellular signal-regulated kinases 1 and 2-dependent and phosphoinositide 3 kinase-independent mechanism. Molecular Pharmacology. 71: 1222-32. PMID 17267664 DOI: 10.1124/Mol.106.027763  0.568
2007 Harkany T, Guzmán M, Galve-Roperh I, Berghuis P, Devi LA, Mackie K. The emerging functions of endocannabinoid signaling during CNS development. Trends in Pharmacological Sciences. 28: 83-92. PMID 17222464 DOI: 10.1016/J.Tips.2006.12.004  0.316
2007 Gupta A, Décaillot FM, Gomes I, Tkalych O, Heimann AS, Ferro ES, Devi LA. Conformation state-sensitive antibodies to G-protein-coupled receptors. The Journal of Biological Chemistry. 282: 5116-24. PMID 17148456 DOI: 10.1074/Jbc.M609254200  0.433
2007 Gendron L, Esdaile MJ, Mennicken F, Pan H, O'Donnell D, Vincent JP, Devi LA, Cahill CM, Stroh T, Beaudet A. Morphine priming in rats with chronic inflammation reveals a dichotomy between antihyperalgesic and antinociceptive properties of deltorphin. Neuroscience. 144: 263-74. PMID 17055663 DOI: 10.1016/J.Neuroscience.2006.08.077  0.365
2007 Morón JA, Abul-Husn NS, Rozenfeld R, Dolios G, Wang R, Devi LA. Morphine administration alters the profile of hippocampal postsynaptic density-associated proteins: a proteomics study focusing on endocytic proteins. Molecular & Cellular Proteomics : McP. 6: 29-42. PMID 17028301 DOI: 10.1074/Mcp.M600184-Mcp200  0.676
2006 Gupta A, Devi LA. The use of receptor-specific antibodies to study G-protein-coupled receptors. The Mount Sinai Journal of Medicine, New York. 73: 673-81. PMID 16878273  0.307
2006 Décaillot FM, Che FY, Fricker LD, Devi LA. Peptidomics of Cpefat/fat mouse hypothalamus and striatum: effect of chronic morphine administration. Journal of Molecular Neuroscience : Mn. 28: 277-84. PMID 16691015 DOI: 10.1385/Jmn:28:3:277  0.402
2006 Rios C, Gomes I, Devi LA. μ opioid and CB1 cannabinoid receptor interactions: Reciprocal inhibition of receptor signaling and neuritogenesis British Journal of Pharmacology. 148: 387-395. PMID 16682964 DOI: 10.1038/Sj.Bjp.0706757  0.495
2006 Breit A, Gagnidze K, Devi LA, Lagacé M, Bouvier M. Simultaneous activation of the delta opioid receptor (deltaOR)/sensory neuron-specific receptor-4 (SNSR-4) hetero-oligomer by the mixed bivalent agonist bovine adrenal medulla peptide 22 activates SNSR-4 but inhibits deltaOR signaling. Molecular Pharmacology. 70: 686-96. PMID 16682504 DOI: 10.1124/Mol.106.022897  0.788
2006 Abul-Husn NS, Devi LA. Neuroproteomics of the synapse and drug addiction. The Journal of Pharmacology and Experimental Therapeutics. 318: 461-8. PMID 16644901 DOI: 10.1124/Jpet.105.091520  0.627
2006 Chakraborty TR, Tkalych O, Nanno D, Garcia AL, Devi LA, Salton SR. Quantification of VGF- and pro-SAAS-derived peptides in endocrine tissues and the brain, and their regulation by diet and cold stress. Brain Research. 1089: 21-32. PMID 16631141 DOI: 10.1016/J.Brainres.2006.02.124  0.329
2006 Gupta A, Décaillot FM, Devi LA. Targeting opioid receptor heterodimers: strategies for screening and drug development. The Aaps Journal. 8: E153-9. PMID 16584123 DOI: 10.1208/Aapsj080118  0.487
2006 Pignatari GC, Rozenfeld R, Ferro ES, Oliveira L, Paiva AC, Devi LA. A role for transmembrane domains V and VI in ligand binding and maturation of the angiotensin II AT1 receptor. Biological Chemistry. 387: 269-76. PMID 16542148 DOI: 10.1515/Bc.2006.036  0.325
2006 Rozenfeld R, Décaillot FM, IJzerman AP, Devi LA. Heterodimers of G protein-coupled receptors as novel and distinct drug targets Drug Discovery Today: Therapeutic Strategies. 3: 437-443. DOI: 10.1016/J.Ddstr.2006.11.001  0.43
2005 He JC, Gomes I, Nguyen T, Jayaram G, Ram PT, Devi LA, Iyengar R. The G alpha(o/i)-coupled cannabinoid receptor-mediated neurite outgrowth involves Rap regulation of Src and Stat3. The Journal of Biological Chemistry. 280: 33426-34. PMID 16046413 DOI: 10.1074/Jbc.M502812200  0.303
2005 Morgan DJ, Mzhavia N, Peng B, Pan H, Devi LA, Pintar JE. Embryonic gene expression and pro-protein processing of proSAAS during rodent development. Journal of Neurochemistry. 93: 1454-62. PMID 15935061 DOI: 10.1111/J.1471-4159.2005.03138.X  0.327
2005 Fricker AD, Rios C, Devi LA, Gomes I. Serotonin receptor activation leads to neurite outgrowth and neuronal survival. Brain Research. Molecular Brain Research. 138: 228-35. PMID 15925428 DOI: 10.1016/J.Molbrainres.2005.04.016  0.46
2005 Pan H, Nanno D, Che FY, Zhu X, Salton SR, Steiner DF, Fricker LD, Devi LA. Neuropeptide processing profile in mice lacking prohormone convertase-1. Biochemistry. 44: 4939-48. PMID 15779921 DOI: 10.1021/Bi047852M  0.337
2005 Jordan JD, He JC, Eungdamrong NJ, Gomes I, Ali W, Nguyen T, Bivona TG, Philips MR, Devi LA, Iyengar R. Cannabinoid receptor-induced neurite outgrowth is mediated by Rap1 activation through G(alpha)o/i-triggered proteasomal degradation of Rap1GAPII. The Journal of Biological Chemistry. 280: 11413-21. PMID 15657046 DOI: 10.1074/Jbc.M411521200  0.312
2004 Rios C, Gomes I, Devi LA. Interactions between δ opioid receptors and α2A- adrenoceptors Clinical and Experimental Pharmacology and Physiology. 31: 833-836. PMID 15566403 DOI: 10.1111/J.1440-1681.2004.04076.X  0.472
2004 Pan H, Mzhavia N, Devi LA. Endothelin converting enzyme-2: a processing enzyme involved in the generation of novel neuropeptides. Protein and Peptide Letters. 11: 461-9. PMID 15544567 DOI: 10.2174/0929866043406463  0.311
2004 Gomes I, Gupta A, Filipovska J, Szeto HH, Pintar JE, Devi LA. A role for heterodimerization of mu and delta opiate receptors in enhancing morphine analgesia. Proceedings of the National Academy of Sciences of the United States of America. 101: 5135-9. PMID 15044695 DOI: 10.1073/Pnas.0307601101  0.489
2003 Jordan BA, Gomes I, Rios C, Filipovska J, Devi LA. Functional interactions between mu opioid and alpha 2A-adrenergic receptors. Molecular Pharmacology. 64: 1317-24. PMID 14645661 DOI: 10.1124/Mol.64.6.1317  0.501
2003 Filipovska J, Gomes I, Xu W, Chen C, Liu-Chen LY, Devi LA. Recombinant opioid receptors. Structure-function relationship. Methods in Molecular Medicine. 84: 185-203. PMID 12703324 DOI: 10.1385/1-59259-379-8:185  0.435
2003 Gomes I, Filipovska J, Devi LA. Opioid receptor oligomerization. Detection and functional characterization of interacting receptors. Methods in Molecular Medicine. 84: 157-83. PMID 12703323 DOI: 10.1385/1-59259-379-8:157  0.455
2003 Mzhavia N, Pan H, Che FY, Fricker LD, Devi LA. Characterization of endothelin-converting enzyme-2. Implication for a role in the nonclassical processing of regulatory peptides. The Journal of Biological Chemistry. 278: 14704-11. PMID 12560336 DOI: 10.1074/Jbc.M211242200  0.325
2002 Boudarine M, Yegorov O, Sterling-Dubrovsky A, Devi LA, Berman Y. Developmental changes in opioid peptides and their receptors in Cpe(fat)/Cpe(fat) mice lacking peptide processing enzyme carboxypeptidase E. The Journal of Pharmacology and Experimental Therapeutics. 303: 1317-24. PMID 12438557 DOI: 10.1124/Jpet.102.037663  0.46
2002 Gomes I, Filipovska J, Jordan BA, Devi LA. Oligomerization of opioid receptors. Methods (San Diego, Calif.). 27: 358-65. PMID 12217652 DOI: 10.1016/S1046-2023(02)00094-4  0.498
2002 Mzhavia N, Qian Y, Feng Y, Che FY, Devi LA, Fricker LD. Processing of proSAAS in neuroendocrine cell lines. The Biochemical Journal. 361: 67-76. PMID 11742530 DOI: 10.1042/0264-6021:3610067  0.345
2002 Hirst RA, Smart D, Devi LA, Lambert DG. Effects of C-Terminal Truncation of the Recombinant δ-Opioid Receptor on Phospholipase C and Adenylyl Cyclase Coupling Journal of Neurochemistry. 70: 2273-2278. PMID 9603191 DOI: 10.1046/J.1471-4159.1998.70062273.X  0.436
2001 Rios CD, Jordan BA, Gomes I, Devi LA. G-protein-coupled receptor dimerization: modulation of receptor function. Pharmacology & Therapeutics. 92: 71-87. PMID 11916530 DOI: 10.1016/S0163-7258(01)00160-7  0.447
2001 Devi LA. Heterodimerization of G-protein-coupled receptors: pharmacology, signaling and trafficking. Trends in Pharmacological Sciences. 22: 532-537. PMID 11583811 DOI: 10.1016/S0165-6147(00)01799-5  0.408
2001 Gomes I, Jordan BA, Gupta A, Rios C, Trapaidze N, Devi LA. G protein coupled receptor dimerization: implications in modulating receptor function. Journal of Molecular Medicine (Berlin, Germany). 79: 226-42. PMID 11485015 DOI: 10.1007/S001090100219  0.465
2001 Che FY, Yan L, Li H, Mzhavia N, Devi LA, Fricker LD. Identification of peptides from brain and pituitary of Cpefat/Cpefat mice Proceedings of the National Academy of Sciences of the United States of America. 98: 9971-9976. PMID 11481435 DOI: 10.1073/Pnas.161542198  0.357
2001 Jordan BA, Trapaidze N, Gomes I, Nivarthi R, Devi LA. Oligomerization of opioid receptors with beta 2-adrenergic receptors: a role in trafficking and mitogen-activated protein kinase activation. Proceedings of the National Academy of Sciences of the United States of America. 98: 343-8. PMID 11134510 DOI: 10.1073/Pnas.011384898  0.468
2001 Mzhavia N, Berman Y, Che FY, Fricker LD, Devi LA. ProSAAS Processing in Mouse Brain and Pituitary Journal of Biological Chemistry. 276: 6207-6213. PMID 11094058 DOI: 10.1074/Jbc.M009067200  0.337
2001 Berman Y, Mzhavia N, Polonskaia A, Devi LA. Impaired Prohormone Convertases inCpefat/CpefatMice Journal of Biological Chemistry. 276: 1466-1473. PMID 11038363 DOI: 10.1074/Jbc.M008499200  0.33
2000 Guo J, Wu Y, Zhang W, Zhao J, Devi LA, Pei G, Ma L. Identification of G Protein-Coupled Receptor Kinase 2 Phosphorylation Sites Responsible for Agonist-Stimulated δ-Opioid Receptor Phosphorylation Molecular Pharmacology. 58: 1050-1056. PMID 11040053 DOI: 10.1124/Mol.58.5.1050  0.457
2000 Jordan BA, Cvejic S, Devi LA. Opioids and their complicated receptor complexes. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 23: S5-S18. PMID 11008063 DOI: 10.1016/S0893-133X(00)00143-3  0.493
2000 Devi LA, Brady LS. Dimerization of G-protein coupled receptors. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 23: S3-4. PMID 11008062 DOI: 10.1016/S0893-133X(00)00154-8  0.388
2000 Berman Y, Mzhavia N, Polonskaia A, Furuta M, Steiner DF, Pintar JE, Devi LA. Defective prodynorphin processing in mice lacking prohormone convertase PC2. Journal of Neurochemistry. 75: 1763-70. PMID 10987860 DOI: 10.1046/J.1471-4159.2000.0751763.X  0.348
2000 Devi LA. G-protein-coupled receptor dimers in the lime light. Trends in Pharmacological Sciences. 21: 324-326. PMID 10973076 DOI: 10.1016/S0165-6147(00)01519-4  0.41
2000 Gomes I, Trapaidze N, Turndorf H, Devi LA, Bansinath M. Acute Ethanol Treatment Modulates δ Opioid Receptors in N18TG2 Cells Anesthesiology. 92: 1789-1798. PMID 10839931 DOI: 10.1097/00000542-200006000-00039  0.36
2000 Trapaidze N, Gomes I, Bansinath M, Devi LA. Recycling and Resensitization of Delta Opioid Receptors Dna and Cell Biology. 19: 195-204. PMID 10798443 DOI: 10.1089/104454900314465  0.471
2000 Trapaidze N, Gomes I, Cvejic S, Bansinath M, Devi LA. Opioid receptor endocytosis and activation of MAP kinase pathway. Molecular Brain Research. 76: 220-228. PMID 10762697 DOI: 10.1016/S0169-328X(00)00002-4  0.467
2000 Trapaidze N, Cvejic S, Nivarthi RN, Abood M, Devi LA. Role for C-tail residues in delta opioid receptor downregulation. Dna and Cell Biology. 19: 93-101. PMID 10701775 DOI: 10.1089/104454900314609  0.483
2000 Jordan BA, Cvejic S, Devi LA. Kappa opioid receptor endocytosis by dynorphin peptides. Dna and Cell Biology. 19: 19-27. PMID 10668788 DOI: 10.1089/104454900314672  0.492
2000 Fricker LD, McKinzie AA, Sun J, Curran E, Qian Y, Yan L, Patterson SD, Courchesne PL, Richards B, Levin N, Mzhavia N, Devi LA, Douglass J. Identification and characterization of proSAAS, a granin-like neuroendocrine peptide precursor that inhibits prohormone processing Journal of Neuroscience. 20: 639-648. PMID 10632593 DOI: 10.1523/Jneurosci.20-02-00639.2000  0.355
2000 Gomes I, Jordan BA, Gupta A, Trapaidze N, Nagy V, Devi LA. Heterodimerization of μ and δ Opioid Receptors: A Role in Opiate Synergy The Journal of Neuroscience. 20: RC110-RC110. DOI: 10.1523/Jneurosci.20-22-J0007.2000  0.484
2000 Gomes IAdS, Gupta A, Devi LA, Turndorf H, Bansinath M. Room E, 10/17/2000 9: 00 AM - 11: 00 AM (PS) Mitogen Activated Protein Kinase Pathway Is Involved in Morphine-Ketamine Interactions A-63 Anesthesiology. 93. DOI: 10.1097/00000542-200009001-00063  0.337
1999 Harrison C, McNulty S, Smart D, Rowbotham DJ, Grandy DK, Devi LA, Lambert DG. The effects of endomorphin-1 and endomorphin-2 in CHO cells expressing recombinant mu-opioid receptors and SH-SY5Y cells. British Journal of Pharmacology. 128: 472-8. PMID 10510460 DOI: 10.1038/Sj.Bjp.0702798  0.366
1999 Harrison C, Rowbotham DJ, Devi LA, Lambert DG. The effect of C-terminal truncation of the recombinant δ-opioid receptor on Cai2+ signaling European Journal of Pharmacology. 379: 237-242. PMID 10497911 DOI: 10.1016/S0014-2999(99)00507-5  0.385
1999 Jordan BA, Devi LA. G-protein-coupled receptor heterodimerization modulates receptor function. Nature. 399: 697-700. PMID 10385123 DOI: 10.1038/21441  0.487
1999 Hirota K, Okawa H, Appadu BL, Grandy DK, Devi LA, Lambert DG. Stereoselective interaction of ketamine with recombinant mu, kappa, and delta opioid receptors expressed in Chinese hamster ovary cells. Anesthesiology. 90: 174-82. PMID 9915326 DOI: 10.1097/00000542-199901000-00023  0.456
1999 Liuzzo JP, Petanceska SS, Devi LA. Neurotrophic factors regulate cathepsin S in macrophages and microglia: A role in the degradation of myelin basic protein and amyloid beta peptide. Molecular Medicine. 5: 334-343. DOI: 10.1007/Bf03402069  0.317
1999 Liuzzo JP, Petanceska SS, Moscatelli D, Devi LA. Inflammatory mediators regulate cathepsin S in macrophages and microglia: A role in attenuating heparan sulfate interactions. Molecular Medicine. 5: 320-333. DOI: 10.1007/Bf03402068  0.321
1998 Jordan B, Devi LA. Molecular mechanisms of opioid receptor signal transduction British Journal of Anaesthesia. 81: 12-19. PMID 9771268 DOI: 10.1093/Bja/81.1.12  0.479
1998 Hirota K, Appadu BL, Grandy DK, Devi LA, Lambert DG. Effect of Lidocaine on cAMP Formation with Recombinant Opioid Receptors Expressed in Chinese Hamster Ovary Cells Anesthesiology. 89: 802A. DOI: 10.1097/00000542-199809130-00108  0.456
1998 Hirota K, Appadu BL, Grandy DK, Devi LA, Lambert DG. Interaction of Local Anesthetics with Recombinant Opioid Receptors Expressed in Chinese Hamster Ovary Cells Anesthesiology. 89: 733A. DOI: 10.1097/00000542-199809130-00039  0.44
1997 Cvejic S, Devi LA. Dimerization of the delta opioid receptor: implication for a role in receptor internalization. Journal of Biological Chemistry. 272: 26959-26964. PMID 9341132 DOI: 10.1074/Jbc.272.43.26959  0.486
1997 Berman Y, Devi L, Spangler R, Kreek MJ, Carr KD. Chronic food restriction and streptozotocin-induced diabetes differentially alter prodynorphin mRNA levels in rat brain regions. Brain Research. Molecular Brain Research. 46: 25-30. PMID 9191075 DOI: 10.1016/S0169-328X(96)00175-1  0.301
1996 Fricker LD, Berman YL, Leiter EH, Devi LA. Carboxypeptidase E activity is deficient in mice with the fat mutation: Effect on peptide processing Journal of Biological Chemistry. 271: 30619-30624. PMID 8940036 DOI: 10.1074/Jbc.271.48.30619  0.331
1996 Trapaidze N, Keith DE, Cvejic S, Evans CJ, Devi LA. Sequestration of the δ opioid receptor: Role of the C terminus in agonist-mediated internalization Journal of Biological Chemistry. 271: 29279-29285. PMID 8910588 DOI: 10.1074/Jbc.271.46.29279  0.486
1996 Cvejic S, Trapaidze N, Cyr C, Devi LA. Thr, Located within the COOH-terminal Tail of the Opiate Receptor, Is Involved in Receptor Down-regulation Journal of Biological Chemistry. 271: 4073-4076. PMID 8626742 DOI: 10.1074/Jbc.271.8.4073  0.447
1995 Berman Y, Devi L, Carr KD. Effects of streptozotocin-induced diabetes on prodynorphin-derived peptides in rat brain regions Brain Research. 685: 129-134. PMID 7583238 DOI: 10.1016/0006-8993(95)00419-Q  0.326
1995 Berman YL, Juliano L, Devi LA. Purification and Characterization of a Dynorphin-processing Endopeptidase Journal of Biological Chemistry. 270: 23845-23850. PMID 7559562 DOI: 10.1074/Jbc.270.40.23845  0.304
1994 Petanceska S, Burke S, Watson SJ, Devi L. Differential distribution of messenger RNAs for cathepsins B, L and S in adult rat brain: an in situ hybridization study. Neuroscience. 59: 729-38. PMID 8008216 DOI: 10.1016/0306-4522(94)90190-2  0.307
1994 Berman Y, Devi L, Carr KD. Effects of chronic food restriction on prodynorphin-derived peptides in rat brain regions Brain Research. 664: 49-53. PMID 7895045 DOI: 10.1016/0006-8993(94)91952-6  0.353
1994 Berman YL, Rattan AK, Carr K, Devi L. Regional distribution of neuropeptide processing endopeptidases in adult rat brain Biochimie. 76: 245-250. PMID 7819330 DOI: 10.1016/0300-9084(94)90153-8  0.308
1993 Petanceska S, Zikherman J, Pricker LD, Devi L. Processing of prodynorphin in BRL-3A cells, a rat liver-derived cell line: implications for the specificity of neuropeptide-processing enzymes. Molecular and Cellular Endocrinology. 94: 37-45. PMID 8375574 DOI: 10.1016/0303-7207(93)90049-P  0.304
1992 Greco L, Daly L, Kim S, Devi L. Dynorphin-processing endopeptidase in the rat anterior pituitary lactotrophic cell line, GH4C1. Neuroendocrinology. 55: 351-356. PMID 1354336 DOI: 10.1159/000126136  0.343
1992 Devi L. Secretion and regulation of a neuropeptide-processing enzyme by AtT-20 cells. Endocrinology. 131: 1930-1935. PMID 1327723 DOI: 10.1210/Endo.131.4.1327723  0.333
1989 Devi L, Gupta P. Expression and Post‐Translational Processing of Preprodynorphin in the Rat Anterior Pituitary Cell Line, GH4C1 Journal of Neuroendocrinology. 1: 363-368. PMID 19210429 DOI: 10.1111/J.1365-2826.1989.Tb00130.X  0.309
1989 Devi L, Gupta P, Douglass J. Expression and posttranslational processing of preprodynorphin complementary DNA in the mouse anterior pituitary cell line AtT-20 Molecular Endocrinology. 3: 1852-1860. PMID 2575215 DOI: 10.1210/Mend-3-11-1852  0.338
1989 McMURRAY CT, Devi L, Calavetta L, Douglass JO. Regulated expression of the prodynorphin gene in the R2C Leydig tumor cell line. Endocrinology. 124: 49-59. PMID 2462494 DOI: 10.1210/Endo-124-1-49  0.305
1986 Devi L, Goldstein A. Opioid and other peptides as inhibitors of leumorphin (dynorphin B-29) converting activity Peptides. 7: 87-90. PMID 3012492 DOI: 10.1016/0196-9781(86)90066-5  0.338
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