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Brian J. Bacskai - Related publications

Affiliations: 
Neurology Massachusetts General Hospital, Boston, MA 
Area:
Alzheimer's
Website:
http://dms.hms.harvard.edu/neuroscience/fac/Bacskai.php
NOTE: We are testing a new system for identifying relevant work based on semantic analysis that identifies similarities between recently published papers and the current author's publications. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches.
50 most relevant papers in past 60 days:
Year Citation  Score
2019 Grimaldi A, Pediconi N, Oieni F, Pizzarelli R, Rosito M, Giubettini M, Santini T, Limatola C, Ruocco G, Ragozzino D, Di Angelantonio S. Neuroinflammatory Processes, A1 Astrocyte Activation and Protein Aggregation in the Retina of Alzheimer's Disease Patients, Possible Biomarkers for Early Diagnosis. Frontiers in Neuroscience. 13: 925. PMID 31551688 DOI: 10.3389/fnins.2019.00925   
2019 Hashimoto M, Yamazaki A, Ohno A, Kimura T, Winblad B, Tjernberg LO. A Fragment of S38AA is a Novel Plasma Biomarker of Alzheimer's Disease. Journal of Alzheimer's Disease : Jad. PMID 31524172 DOI: 10.3233/JAD-190700   
2019 Ahmad SS, Khan S, Kamal MA, Wasi U. The structure and function of α, β and γ-Secretase as therapeutic target enzymes into the development of Alzheimer's disease: A review. Cns & Neurological Disorders Drug Targets. PMID 31608840 DOI: 10.2174/1871527318666191011145941   
2019 Chen Y, Xu J, Zhou X, Liu S, Zhang Y, Ma S, Fu AKY, Ip NY, Chen Y. Changes of protein phosphorylation are associated with synaptic functions during the early stage of Alzheimer's disease. Acs Chemical Neuroscience. PMID 31424205 DOI: 10.1021/acschemneuro.9b00190   
2019 Tian X, Xie B, Zou Z, Jiao Y, Lin LE, Chen CL, Hsu CC, Peng J, Yang Z. Multimodal Imaging of Amyloid Plaques: Fusion of the Single-probe Mass Spectrometry Image and Fluorescence Microscopy Image. Analytical Chemistry. PMID 31536324 DOI: 10.1021/acs.analchem.9b02792   
2019 Xie Y, Niu M, Ji C, Huang TY, Zhang C, Tian Y, Shi Z, Wang C, Zhao Y, Luo H, Can D, Xu H, Zhang YW, Zhang X. SNX8 Enhances Non-amyloidogenic APP Trafficking and Attenuates Aβ Accumulation and Memory Deficits in an AD Mouse. Frontiers in Cellular Neuroscience. 13: 410. PMID 31551717 DOI: 10.3389/fncel.2019.00410   
2019 Tiwari S, Atluri V, Kaushik A, Yndart A, Nair M. Alzheimer's disease: pathogenesis, diagnostics, and therapeutics. International Journal of Nanomedicine. 14: 5541-5554. PMID 31410002 DOI: 10.2147/IJN.S200490   
2019 Matsuda H, Shigemoto Y, Sato N. Neuroimaging of Alzheimer's disease: focus on amyloid and tau PET. Japanese Journal of Radiology. PMID 31493197 DOI: 10.1007/s11604-019-00867-7   
2019 Liu J, Li L. Targeting Autophagy for the Treatment of Alzheimer's Disease: Challenges and Opportunities. Frontiers in Molecular Neuroscience. 12: 203. PMID 31507373 DOI: 10.3389/fnmol.2019.00203   
2019 Mputhia Z, Hone E, Tripathi T, Sargeant T, Martins R, Bharadwaj P. Autophagy Modulation as a Treatment of Amyloid Diseases. Molecules (Basel, Switzerland). 24. PMID 31527516 DOI: 10.3390/molecules24183372   
2019 Cheng CH, Lin KJ, Hong CT, Wu D, Chang HM, Liu CH, Hsiao IT, Yang CP, Liu YC, Hu CJ. Plasmon-Activated Water Reduces Amyloid Burden and Improves Memory in Animals with Alzheimer's Disease. Scientific Reports. 9: 13252. PMID 31520077 DOI: 10.1038/s41598-019-49731-8   
2019 Stefanovski L, Triebkorn P, Spiegler A, Diaz-Cortes MA, Solodkin A, Jirsa V, McIntosh AR, Ritter P, . Linking Molecular Pathways and Large-Scale Computational Modeling to Assess Candidate Disease Mechanisms and Pharmacodynamics in Alzheimer's Disease. Frontiers in Computational Neuroscience. 13: 54. PMID 31456676 DOI: 10.3389/fncom.2019.00054   
2019 Wu T, Dejanovic B, Gandham VD, Gogineni A, Edmonds R, Schauer S, Srinivasan K, Huntley MA, Wang Y, Wang TM, Hedehus M, Barck KH, Stark M, Ngu H, Foreman O, et al. Complement C3 Is Activated in Human AD Brain and Is Required for Neurodegeneration in Mouse Models of Amyloidosis and Tauopathy. Cell Reports. 28: 2111-2123.e6. PMID 31433986 DOI: 10.1016/j.celrep.2019.07.060   
2019 Yanagawa T, Takao M, Yasuda M, Kamide T, Sato H, Suzuki K, Ikeda T, Kikkawa Y, Kurita H. Clinical and neuropathologic analysis of intracerebral hemorrhage in patients with cerebral amyloid angiopathy. Clinical Neurology and Neurosurgery. 176: 110-115. PMID 30554091 DOI: 10.1016/j.clineuro.2018.11.020   
2019 Giorgi FS, Saccaro LF, Galgani A, Busceti CL, Biagioni F, Frati A, Fornai F. The role of Locus Coeruleus in neuroinflammation occurring in Alzheimer's disease. Brain Research Bulletin. 153: 47-58. PMID 31419539 DOI: 10.1016/j.brainresbull.2019.08.007   
2019 Polis B, Gurevich V, Assa M, Samson AO. Norvaline Restores the BBB Integrity in a Mouse Model of Alzheimer's Disease. International Journal of Molecular Sciences. 20. PMID 31540372 DOI: 10.3390/ijms20184616   
2019 Fan W, Sun Y, Shi Z, Wang H, Deng J. Mouse Induced Pluripotent Stem Cells-Derived Alzheimer's Disease Cerebral Organoid Culture and Neural Differentiation Disorders. Neuroscience Letters. 134433. PMID 31421155 DOI: 10.1016/j.neulet.2019.134433   
2019 Caruso A, Nicoletti F, Gaetano A, Scaccianoce S. Risk Factors for Alzheimer's Disease: Focus on Stress. Frontiers in Pharmacology. 10: 976. PMID 31551781 DOI: 10.3389/fphar.2019.00976   
2019 Chandra A, Valkimadi PE, Pagano G, Cousins O, Dervenoulas G, Politis M, . Applications of amyloid, tau, and neuroinflammation PET imaging to Alzheimer's disease and mild cognitive impairment. Human Brain Mapping. PMID 31520513 DOI: 10.1002/hbm.24782   
2019 Caleb AA, Akiyama T, Kimura A, Kimura Y, Takahashi-Jitsuki A, Nakamura H, Makihara H, Masukawa D, Nakabayashi J, Hirano H, Nakamura F, Saito T, Saido T, Goshima Y. Network-guided analysis of hippocampal proteome identifies novel proteins that colocalize with Aβ in a mice model of early-stage Alzheimer's disease. Neurobiology of Disease. 104603. PMID 31494281 DOI: 10.1016/j.nbd.2019.104603   
2019 Naushad M, Durairajan SSK, Bera AK, Senapati S, Li M. Natural Compounds with Anti-BACE1 Activity as Promising Therapeutic Drugs for Treating Alzheimer's Disease. Planta Medica. PMID 31618777 DOI: 10.1055/a-1019-9819   
2019 Kisby B, Jarrell JT, Agar ME, Cohen DS, Rosin ER, Cahill CM, Rogers JT, Huang X. Alzheimer's Disease and Its Potential Alternative Therapeutics. Journal of Alzheimer's Disease & Parkinsonism. 9. PMID 31588368 DOI: 10.4172/2161-0460.1000477   
2019 Pietronigro E, Zenaro E, Bianca VD, Dusi S, Terrabuio E, Iannoto G, Slanzi A, Ghasemi S, Nagarajan R, Piacentino G, Tosadori G, Rossi B, Constantin G. Blockade of α4 integrins reduces leukocyte-endothelial interactions in cerebral vessels and improves memory in a mouse model of Alzheimer's disease. Scientific Reports. 9: 12055. PMID 31427644 DOI: 10.1038/s41598-019-48538-x   
2019 Long JM, Holtzman DM. Alzheimer Disease: An Update on Pathobiology and Treatment Strategies. Cell. 179: 312-339. PMID 31564456 DOI: 10.1016/j.cell.2019.09.001   
2019 Wang H, Shen Y, Chuang H, Chiu C, Ye Y, Zhao L. Neuroinflammation in Alzheimer's Disease: Microglia, Molecular Participants and Therapeutic Choices. Current Alzheimer Research. 16: 659-674. PMID 31580243 DOI: 10.2174/1567205016666190503151648   
2019 Sun H, Liu M, Sun T, Chen Y, Lan Z, Lian B, Zhao C, Liu Z, Zhang J, Liu Y. Age-related changes in hippocampal AD pathology, actin remodeling proteins and spatial memory behavior of male APP/PS1 mice. Behavioural Brain Research. 112182. PMID 31472195 DOI: 10.1016/j.bbr.2019.112182   
2019 Gary C, Lam S, Hérard AS, Koch JE, Petit F, Gipchtein P, Sawiak SJ, Caillierez R, Eddarkaoui S, Colin M, Aujard F, Deslys JP, , Brouillet E, Buée L, et al. Encephalopathy induced by Alzheimer brain inoculation in a non-human primate. Acta Neuropathologica Communications. 7: 126. PMID 31481130 DOI: 10.1186/s40478-019-0771-x   
2019 Chen X, Xu B, Nie L, He K, Zhou L, Huang X, Spencer P, Yang X, Liu J. Flavanol-rich lychee fruit extract substantially reduces progressive cognitive and molecular deficits in a triple-transgenic animal model of Alzheimer disease. Nutritional Neuroscience. 1-15. PMID 31603034 DOI: 10.1080/1028415X.2019.1673527   
2019 Xicota L, Ichou F, Lejeune FX, Colsch B, Tenenhaus A, Leroy I, Fontaine G, Lhomme M, Bertin H, Habert MO, Epelbaum S, Dubois B, Mochel F, Potier MC, . Multi-omics signature of brain amyloid deposition in asymptomatic individuals at-risk for Alzheimer's disease: The INSIGHT-preAD study. Ebiomedicine. PMID 31492558 DOI: 10.1016/j.ebiom.2019.08.051   
2019 Sun MK, Alkon DL. Neuro-regeneration Therapeutic for Alzheimer's Dementia: Perspectives on Neurotrophic Activity. Trends in Pharmacological Sciences. 40: 655-668. PMID 31402121 DOI: 10.1016/j.tips.2019.07.008   
2019 Park JC, Han SH, Lee H, Jeong H, Byun MS, Bae J, Kim H, Young Lee D, Yi D, Shin SA, Kim YK, Hwang D, Lee SW, Mook-Jung I. Prognostic plasma protein panel for Aβ deposition in the brain in Alzheimer's disease. Progress in Neurobiology. 101690. PMID 31605717 DOI: 10.1016/j.pneurobio.2019.101690   
2019 Chaudhuri P, Prajapati KP, Anand BG, Dubey K, Kar K. Amyloid cross-seeding raises new dimensions to understanding of amyloidogenesis mechanism. Ageing Research Reviews. 100937. PMID 31430565 DOI: 10.1016/j.arr.2019.100937   
2019 Liu K, Ma C, Su J, Sun Y, Shen N, Li B, Feng Y, Yang X, Wu H, Zhang H, Herrmann A, Tanzi R, Zhang C. Significant upregulation of Alzheimer's β-amyloid levels in living system induced by extracellular elastin polypeptides. Angewandte Chemie (International Ed. in English). PMID 31609093 DOI: 10.1002/anie.201912399   
2019 Chen Y, Li M, Zheng Y, Yang L. Evaluation of Hemisphere Lateralization with Bilateral Local Field Potential Recording in Secondary Motor Cortex of Mice. Journal of Visualized Experiments : Jove. PMID 31424430 DOI: 10.3791/59310   
2019 Griner SL, Seidler P, Bowler J, Murray KA, Yang TP, Sahay S, Sawaya MR, Cascio D, Rodriguez JA, Philipp S, Sosna J, Glabe CG, Gonen T, Eisenberg DS. Structure based inhibitors of Amyloid Beta core suggest a common interface with Tau. Elife. 8. PMID 31612856 DOI: 10.7554/eLife.46924   
2019 Pradeepkiran JA, Reddy AP, Yin X, Manczak M, Reddy PH. Protective Effects of BACE1 Inhibitory Ligand Molecules Against Amyloid Beta-Induced Synaptic and Mitochondrial Toxicities in Alzheimer's Disease. Human Molecular Genetics. PMID 31595293 DOI: 10.1093/hmg/ddz227   
2019 Chernova TA, Chernoff YO, Wilkinson KD. Yeast Models for Amyloids and Prions: Environmental Modulation and Drug Discovery. Molecules (Basel, Switzerland). 24. PMID 31540362 DOI: 10.3390/molecules24183388   
2019 Dupont G, Iwanaga J, Yilmaz E, Tubbs RS. Connections Between Amyloid Beta and the Meningeal Lymphatics As a Possible Route for Clearance and Therapeutics. Lymphatic Research and Biology. PMID 31433264 DOI: 10.1089/lrb.2018.0079   
2019 Urfer SR, Latimer CS, Ladiges W, Keene CD, Benbow S, Harrison B, Promislow DEL, Kaeberlein M, Kraemer BC, Wang A, Guscetti F, Darvas M. Cross species application of quantitative neuropathology assays developed for clinical Alzheimer's disease samples. Pathobiology of Aging & Age Related Diseases. 9: 1657768. PMID 31528297 DOI: 10.1080/20010001.2019.1657768   
2019 Islam T, Gharibyan AL, Golchin SA, Pettersson N, Brännström K, Hedberg I, Virta MM, Olofsson L, Olofsson A. Apolipoprotein E impairs amyloid-β fibril elongation and maturation. The Febs Journal. PMID 31571352 DOI: 10.1111/febs.15075   
2019 Bernabeu-Zornoza A, Coronel R, Palmer C, Monteagudo M, Zambrano A, Liste I. Physiological and pathological effects of amyloid-β species in neural stem cell biology. Neural Regeneration Research. 14: 2035-2042. PMID 31397330 DOI: 10.4103/1673-5374.262571   
2019 Nam Y, Joo B, Lee JY, Han KM, Ryu KY, Koh YH, Kim J, Koo JW, We YM, Hoe HS. ALWPs Improve Cognitive Function and Regulate Aβ Plaque and Tau Hyperphosphorylation in a Mouse Model of Alzheimer's Disease. Frontiers in Molecular Neuroscience. 12: 192. PMID 31474828 DOI: 10.3389/fnmol.2019.00192   
2019 Jack CR, Wiste HJ, Botha H, Weigand SD, Therneau TM, Knopman DS, Graff-Radford J, Jones DT, Ferman TJ, Boeve BF, Kantarci K, Lowe VJ, Vemuri P, Mielke MM, Fields JA, et al. The bivariate distribution of amyloid-β and tau: relationship with established neurocognitive clinical syndromes. Brain : a Journal of Neurology. PMID 31501889 DOI: 10.1093/brain/awz268   
2019 Bertoux M, Lagarde J, Corlier F, Hamelin L, Mangin JF, Colliot O, Chupin M, Braskie MN, Thompson PM, Bottlaender M, Sarazin M. Sulcal morphology in Alzheimer's disease: an effective marker of diagnosis and cognition. Neurobiology of Aging. 84: 41-49. PMID 31491594 DOI: 10.1016/j.neurobiolaging.2019.07.015   
2019 Doens D, Valdés-Tresanco ME, Vasquez V, Carreira MB, De La Guardia Y, Stephens DE, Nguyen VD, Nguyen VT, Gu J, Hegde M, Larionov OV, Valiente PA, Lleonart R, L Fernandez P. Hexahydropyrrolo[2,3-b]indole compounds as potential therapeutics for Alzheimer Disease. Acs Chemical Neuroscience. PMID 31545596 DOI: 10.1021/acschemneuro.9b00297   
2019 Sanchez-Mejias E, Nuñez-Diaz C, Sanchez-Varo R, Gomez-Arboledas A, Garcia-Leon JA, Fernandez-Valenzuela JJ, Mejias-Ortega M, Trujillo-Estrada L, Baglietto-Vargas D, Moreno-Gonzalez I, Davila JC, Vitorica J, Gutierrez A. Distinct disease-sensitive GABAergic neurons in the perirhinal cortex of Alzheimer's mice and patients. Brain Pathology (Zurich, Switzerland). PMID 31491047 DOI: 10.1111/bpa.12785   
2019 Yagensky O, Kohansal-Nodehi M, Gunaseelan S, Rabe T, Zafar S, Zerr I, Haertig W, Urlaub H, Chua JJ. Increased expression of heme-binding protein 1 early in Alzheimer's disease is linked to neurotoxicity. Elife. 8. PMID 31453805 DOI: 10.7554/eLife.47498   
2019 McRae-McKee K, Udeh-Momoh CT, Price G, Bajaj S, de Jager CA, Scott D, Hadjichrysanthou C, McNaughton E, Bracoud L, Ahmadi-Abhari S, de Wolf F, Anderson RM, Middleton LT, . Perspective: Clinical relevance of the dichotomous classification of Alzheimer's disease biomarkers: Should there be a "gray zone"? Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 31564609 DOI: 10.1016/j.jalz.2019.07.010   
2019 Carandini T, Arighi A, Sacchi L, Fumagalli GG, Pietroboni AM, Ghezzi L, Colombi A, Scarioni M, Fenoglio C, De Riz MA, Marotta G, Scarpini E, Galimberti D. Testing the 2018 NIA-AA research framework in a retrospective large cohort of patients with cognitive impairment: from biological biomarkers to clinical syndromes. Alzheimer's Research & Therapy. 11: 84. PMID 31615545 DOI: 10.1186/s13195-019-0543-7   
2019 Velazquez R, Ferreira E, Knowles S, Fux C, Rodin A, Winslow W, Oddo S. Lifelong choline supplementation ameliorates Alzheimer's disease pathology and associated cognitive deficits by attenuating microglia activation. Aging Cell. e13037. PMID 31560162 DOI: 10.1111/acel.13037