Peter A. Friedman - Publications

Affiliations: 
Pharmacology University of Pittsburgh School of Medicine, Pittsburgh, PA, United States 
Area:
Receptor Pharmacology, Signal Transduction
Website:
http://www.pharmacology.us/Faculty/PeterFriedman

73 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Friedman PA, Sneddon WB, Mamonova T, Montanez-Miranda C, Ramineni S, Harbin NH, Squires KE, Gefter JV, Magyar CE, Emlet DR, Hepler JR. RGS14 regulates hormone-sensitive NPT2A-mediated renal phosphate uptake via binding to the NHERF1 scaffolding protein. The Journal of Biological Chemistry. 101836. PMID 35307350 DOI: 10.1016/j.jbc.2022.101836  0.315
2020 Suva LJ, Friedman PA. PTH and PTHrP Actions on Bone. Handbook of Experimental Pharmacology. PMID 32462362 DOI: 10.1007/164_2020_362  0.343
2019 Martins JS, Liu ES, Sneddon WB, Friedman PA, Demay MB. 1,25-dihydroxyvitamin D maintains brush border membrane NaPi2a and attenuates phosphaturia in Hyp mice. Endocrinology. PMID 31237611 DOI: 10.1210/En.2019-00186  0.358
2019 Bhattacharya S, Stanley CB, Heller WT, Friedman PA, Bu Z. Dynamic structure of the full-length scaffolding protein NHERF1 influences signaling complex assembly. The Journal of Biological Chemistry. PMID 31171716 DOI: 10.1074/Jbc.Ra119.008218  0.323
2019 Jeong J, Kim W, Hens J, Dann P, Schedin P, Friedman PA, Wysolmerski JJ. NHERF1 is Required for Localization of PMCA2 and Suppression of Early Involution in the Female Lactating Mammary Gland. Endocrinology. PMID 31087002 DOI: 10.1210/En.2019-00230  0.369
2019 Liu H, Wang D, Zhang Q, Zhao Y, Mamonova T, Wang L, Zhang C, Li S, Friedman PA, Xiao K. Parallel PTM scanning enhances HDXMS coverage of key structural regions. Analytical Chemistry. PMID 31082219 DOI: 10.1021/Acs.Analchem.9B01410  0.306
2019 Zhang Q, Xiao K, Paredes JM, Mamonova T, Sneddon WB, Liu H, Wang D, Li S, McGarvey JC, Uehling D, Al-Awar R, Joseph B, Jean-Alphonse F, Orte A, Friedman PA. Parathyroid hormone initiates dynamic NHERF1 phosphorylation cycling and conformational changes that regulate NPT2A-dependent phosphate transport. The Journal of Biological Chemistry. PMID 30696771 DOI: 10.1074/Jbc.Ra119.007421  0.363
2018 Jeong J, Choi J, Kim W, Dann P, Takyar F, Gefter JV, Friedman PA, Wysolmerski J. Inhibition of ezrin causes PKCα-mediated internalization of erbb2/HER2 tyrosine kinase in breast cancer cells. The Journal of Biological Chemistry. PMID 30463939 DOI: 10.1074/Jbc.Ra118.004143  0.31
2018 Zhang Q, Xiao K, Liu H, Song L, McGarvey JC, Sneddon WB, Bisello A, Friedman PA. Site-specific polyubiquitination differentially regulates parathyroid hormone receptor-initiated MAPK signaling and cell proliferation. The Journal of Biological Chemistry. PMID 29444827 DOI: 10.1074/Jbc.Ra118.001737  0.364
2017 Kittikulsuth W, Friedman PA, van Hoek A, Gao Y, Kohan DE. Identification of adenylyl cyclase isoforms mediating parathyroid hormone- and calcitonin-stimulated cyclic AMP accumulation in distal tubule cells. Bmc Nephrology. 18: 292. PMID 28882112 DOI: 10.1186/S12882-017-0712-5  0.35
2017 Mamonova T, Zhang Q, Chandra M, Collins B, Sarfo EK, Bu Z, Xiao K, Bisello A, Friedman PA. Origins of PDZ Binding Specificity. A Computational and Experimental Study Using NHERF1 and the Parathyroid Hormone Receptor. Biochemistry. PMID 28376304 DOI: 10.1021/Acs.Biochem.7B00078  0.349
2017 Jeong J, Vanhouten JN, Kim W, Dann P, Sullivan C, Choi J, Sneddon WB, Friedman PA, Wysolmerski JJ. The Scaffolding protein NHERF1 Regulates the Stability and Activity of the Tyrosine Kinase HER2. The Journal of Biological Chemistry. PMID 28235801 DOI: 10.1074/Jbc.M116.770883  0.328
2016 Ardura JA, Alonso V, Esbrit P, Friedman PA. Oxidation inhibits PTH receptor signaling and trafficking. Biochemical and Biophysical Research Communications. PMID 27908723 DOI: 10.1016/J.Bbrc.2016.11.150  0.337
2016 Pavlos NJ, Friedman PA. GPCR Signaling and Trafficking: The Long and Short of It. Trends in Endocrinology and Metabolism: Tem. PMID 27889227 DOI: 10.1016/J.Tem.2016.10.007  0.364
2016 Sneddon WB, Ruiz GW, Gallo LI, Xiao K, Zhang Q, Rbaibi Y, Weisz OA, Apodaca GL, Friedman PA. Convergent Signaling Pathways Regulate Parathyroid Hormone and Fibroblast Growth Factor-23 Action on NPT2A-mediated Phosphate Transport. The Journal of Biological Chemistry. PMID 27432882 DOI: 10.1074/Jbc.M116.744052  0.396
2016 Treat AC, Wheeler DS, Stolz DB, Tsang M, Friedman PA, Romero G. The PDZ Protein Na+/H+ Exchanger Regulatory Factor-1 (NHERF1) Regulates Planar Cell Polarity and Motile Cilia Organization. Plos One. 11: e0153144. PMID 27055101 DOI: 10.1371/Journal.Pone.0153144  0.327
2016 Pereira RC, Andersen TL, Friedman PA, Tumber N, Salusky IB, Wesseling-Perry K. Bone Canopies in Pediatric Renal Osteodystrophy. Plos One. 11: e0152871. PMID 27045269 DOI: 10.1371/Journal.Pone.0152871  0.318
2016 McGarvey JC, Xiao K, Bowman SL, Mamonova T, Zhang Q, Bisello A, Sneddon WB, Ardura JA, Jean-Alphonse F, Vilardaga JP, Puthenveedu MA, Friedman PA. Actin-Sorting Nexin 27-Retromer Complex Mediates Rapid Parathyroid Hormone Receptor Recycling. The Journal of Biological Chemistry. PMID 27008860 DOI: 10.1074/Jbc.M115.697045  0.379
2016 Jeong J, VanHouten JN, Dann P, Kim W, Sullivan C, Yu H, Liotta L, Espina V, Stern DF, Friedman PA, Wysolmerski JJ. PMCA2 regulates HER2 protein kinase localization and signaling and promotes HER2-mediated breast cancer. Proceedings of the National Academy of Sciences of the United States of America. PMID 26729871 DOI: 10.1073/Pnas.1516138113  0.308
2015 Mamonova T, Zhang Q, Khajeh JA, Bu Z, Bisello A, Friedman PA. Canonical and Noncanonical Sites Determine NPT2A Binding Selectivity to NHERF1 PDZ1. Plos One. 10: e0129554. PMID 26070212 DOI: 10.1371/Journal.Pone.0129554  0.323
2015 Gattineni J, Friedman PA. Regulation of hormone-sensitive renal phosphate transport. Vitamins and Hormones. 98: 249-306. PMID 25817872 DOI: 10.1016/Bs.Vh.2015.01.002  0.335
2015 Song GJ, Leslie KL, Barrick S, Mamonova T, Fitzpatrick JM, Drombosky KW, Peyser N, Wang B, Pellegrini M, Bauer PM, Friedman PA, Mierke DF, Bisello A. Phosphorylation of ezrin-radixin-moesin-binding phosphoprotein 50 (EBP50) by Akt promotes stability and mitogenic function of S-phase kinase-associated protein-2 (Skp2). The Journal of Biological Chemistry. 290: 2879-87. PMID 25492869 DOI: 10.1074/Jbc.M114.609768  0.352
2014 Mamonova T, Bisello A, Friedman PA. Modeling and Experimental Study of NHERF1 PDZ Domain Specificity Biophysical Journal. 106: 661a-662a. DOI: 10.1016/J.Bpj.2013.11.3662  0.314
2013 Alonso V, Friedman PA. Minireview: ubiquitination-regulated G protein-coupled receptor signaling and trafficking. Molecular Endocrinology (Baltimore, Md.). 27: 558-72. PMID 23471539 DOI: 10.1210/Me.2012-1404  0.331
2013 Wang B, Yang Y, Liu L, Blair HC, Friedman PA. NHERF1 regulation of PTH-dependent bimodal Pi transport in osteoblasts. Bone. 52: 268-77. PMID 23046970 DOI: 10.1016/J.Bone.2012.10.001  0.355
2012 Liu L, Alonso V, Guo L, Tourkova I, Henderson SE, Almarza AJ, Friedman PA, Blair HC. Na+/H+ exchanger regulatory factor 1 (NHERF1) directly regulates osteogenesis. The Journal of Biological Chemistry. 287: 43312-21. PMID 23109343 DOI: 10.1074/Jbc.M112.422766  0.322
2012 Wang B, Means CK, Yang Y, Mamonova T, Bisello A, Altschuler DL, Scott JD, Friedman PA. Ezrin-anchored protein kinase A coordinates phosphorylation-dependent disassembly of a NHERF1 ternary complex to regulate hormone-sensitive phosphate transport. The Journal of Biological Chemistry. 287: 24148-63. PMID 22628548 DOI: 10.1074/Jbc.M112.369405  0.344
2012 Mamonova T, Kurnikova M, Friedman PA. Structural basis for NHERF1 PDZ domain binding. Biochemistry. 51: 3110-20. PMID 22429102 DOI: 10.1021/Bi201213W  0.321
2012 Song GJ, Barrick S, Leslie KL, Bauer PM, Alonso V, Friedman PA, Fiaschi-Taesch NM, Bisello A. The scaffolding protein EBP50 promotes vascular smooth muscle cell proliferation and neointima formation by regulating Skp2 and p21(cip1). Arteriosclerosis, Thrombosis, and Vascular Biology. 32: 33-41. PMID 22034511 DOI: 10.1161/Atvbaha.111.235200  0.311
2011 Romero G, von Zastrow M, Friedman PA. Role of PDZ proteins in regulating trafficking, signaling, and function of GPCRs: means, motif, and opportunity. Advances in Pharmacology (San Diego, Calif.). 62: 279-314. PMID 21907913 DOI: 10.1016/B978-0-12-385952-5.00003-8  0.347
2011 Alonso V, Magyar CE, Wang B, Bisello A, Friedman PA. Ubiquitination-deubiquitination balance dictates ligand-stimulated PTHR sorting. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 26: 2923-34. PMID 21898592 DOI: 10.1002/Jbmr.494  0.384
2011 Ardura JA, Friedman PA. Regulation of G protein-coupled receptor function by Na+/H+ exchange regulatory factors. Pharmacological Reviews. 63: 882-900. PMID 21873413 DOI: 10.1124/Pr.110.004176  0.366
2011 Ardura JA, Wang B, Watkins SC, Vilardaga JP, Friedman PA. Dynamic Na+-H+ exchanger regulatory factor-1 association and dissociation regulate parathyroid hormone receptor trafficking at membrane microdomains. The Journal of Biological Chemistry. 286: 35020-9. PMID 21832055 DOI: 10.1074/Jbc.M111.264978  0.397
2011 Blair HC, Robinson LJ, Huang CL, Sun L, Friedman PA, Schlesinger PH, Zaidi M. Calcium and bone disease. Biofactors (Oxford, England). 37: 159-67. PMID 21674636 DOI: 10.1002/Biof.143  0.325
2011 Liu L, Schlesinger PH, Slack NM, Friedman PA, Blair HC. High capacity Na+/H+ exchange activity in mineralizing osteoblasts. Journal of Cellular Physiology. 226: 1702-12. PMID 21413028 DOI: 10.1002/Jcp.22501  0.301
2011 Wheeler DS, Barrick SR, Grubisha MJ, Brufsky AM, Friedman PA, Romero G. Direct interaction between NHERF1 and Frizzled regulates Β-catenin signaling Oncogene. 30: 32-42. PMID 20802536 DOI: 10.1038/Onc.2010.389  0.328
2011 Vilardaga JP, Romero G, Friedman PA, Gardella TJ. Molecular basis of parathyroid hormone receptor signaling and trafficking: a family B GPCR paradigm. Cellular and Molecular Life Sciences : Cmls. 68: 1-13. PMID 20703892 DOI: 10.1007/S00018-010-0465-9  0.389
2011 Alonso V, Ardura JA, Wang B, Sneddon WB, Friedman PA. A naturally occurring isoform inhibits parathyroid hormone receptor trafficking and signaling. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 26: 143-55. PMID 20578167 DOI: 10.1002/Jbmr.167  0.364
2010 Klenk C, Vetter T, Zürn A, Vilardaga JP, Friedman PA, Wang B, Lohse MJ. Formation of a ternary complex among NHERF1, beta-arrestin, and parathyroid hormone receptor. The Journal of Biological Chemistry. 285: 30355-62. PMID 20656684 DOI: 10.1074/Jbc.M110.114900  0.4
2010 Romero G, Sneddon WB, Yang Y, Wheeler D, Blair HC, Friedman PA. Parathyroid hormone receptor directly interacts with dishevelled to regulate beta-Catenin signaling and osteoclastogenesis. The Journal of Biological Chemistry. 285: 14756-63. PMID 20212039 DOI: 10.1074/Jbc.M110.102970  0.346
2010 Ardura JA, Vilardaga J, Friedman PA. Protein-Exchange Dynamics at GPCR Micro-Domains: a Case Study with the Parathyroid Hormone Receptor Biophysical Journal. 98: 432a. DOI: 10.1016/J.Bpj.2009.12.2346  0.377
2009 Garrido JL, Wheeler D, Vega LL, Friedman PA, Romero G. Role of phospholipase D in parathyroid hormone type 1 receptor signaling and trafficking. Molecular Endocrinology (Baltimore, Md.). 23: 2048-59. PMID 19837945 DOI: 10.1210/Me.2008-0436  0.38
2009 Wang B, Yang Y, Abou-Samra AB, Friedman PA. NHERF1 regulates parathyroid hormone receptor desensitization: interference with beta-arrestin binding. Molecular Pharmacology. 75: 1189-97. PMID 19188335 DOI: 10.1124/Mol.108.054486  0.415
2009 Gamba G, Friedman PA. Thick ascending limb: the Na(+):K (+):2Cl (-) co-transporter, NKCC2, and the calcium-sensing receptor, CaSR. PflüGers Archiv : European Journal of Physiology. 458: 61-76. PMID 18982348 DOI: 10.1007/S00424-008-0607-1  0.356
2008 Sebastian EM, Suva LJ, Friedman PA. Differential effects of intermittent PTH(1-34) and PTH(7-34) on bone microarchitecture and aortic calcification in experimental renal failure. Bone. 43: 1022-30. PMID 18761112 DOI: 10.1016/J.Bone.2008.07.250  0.314
2008 Wang B, Yang Y, Friedman PA. Na/H exchange regulatory factor 1, a novel AKT-associating protein, regulates extracellular signal-regulated kinase signaling through a B-Raf-mediated pathway. Molecular Biology of the Cell. 19: 1637-45. PMID 18272783 DOI: 10.1091/Mbc.E07-11-1114  0.378
2008 Wheeler D, Garrido JL, Bisello A, Kim YK, Friedman PA, Romero G. Regulation of parathyroid hormone type 1 receptor dynamics, traffic, and signaling by the Na+/H+ exchanger regulatory factor-1 in rat osteosarcoma ROS 17/2.8 cells. Molecular Endocrinology (Baltimore, Md.). 22: 1163-70. PMID 18202147 DOI: 10.1210/Me.2007-0461  0.407
2007 Wang B, Bisello A, Yang Y, Romero GG, Friedman PA. NHERF1 regulates parathyroid hormone receptor membrane retention without affecting recycling. The Journal of Biological Chemistry. 282: 36214-22. PMID 17884816 DOI: 10.1074/Jbc.M707263200  0.418
2007 Vasavada RC, Wang L, Fujinaka Y, Takane KK, Rosa TC, Mellado-Gil JM, Friedman PA, Garcia-Ocaña A. Protein kinase C-zeta activation markedly enhances beta-cell proliferation: an essential role in growth factor mediated beta-cell mitogenesis. Diabetes. 56: 2732-43. PMID 17686945 DOI: 10.2337/Db07-0461  0.305
2007 Wheeler D, Sneddon WB, Wang B, Friedman PA, Romero G. NHERF-1 and the cytoskeleton regulate the traffic and membrane dynamics of G protein-coupled receptors. The Journal of Biological Chemistry. 282: 25076-87. PMID 17599914 DOI: 10.1074/Jbc.M701544200  0.348
2007 Sneddon WB, Friedman PA. Beta-arrestin-dependent parathyroid hormone-stimulated extracellular signal-regulated kinase activation and parathyroid hormone type 1 receptor internalization. Endocrinology. 148: 4073-9. PMID 17525124 DOI: 10.1210/En.2007-0343  0.396
2007 Sneddon WB, Yang Y, Ba J, Harinstein LM, Friedman PA. Extracellular signal-regulated kinase activation by parathyroid hormone in distal tubule cells. American Journal of Physiology. Renal Physiology. 292: F1028-34. PMID 17107942 DOI: 10.1152/Ajprenal.00288.2006  0.394
2006 Friedman PA, Goodman WG. PTH(1-84)/PTH(7-84): a balance of power. American Journal of Physiology. Renal Physiology. 290: F975-84. PMID 16601298 DOI: 10.1152/Ajprenal.00336.2005  0.321
2006 Weinman EJ, Hall RA, Friedman PA, Liu-Chen LY, Shenolikar S. The association of NHERF adaptor proteins with g protein-coupled receptors and receptor tyrosine kinases. Annual Review of Physiology. 68: 491-505. PMID 16460281 DOI: 10.1146/Annurev.Physiol.68.040104.131050  0.365
2006 Srinivasan R, Wolfe D, Huang S, Krisky D, Sculptoreanu A, Friedman PA, de Groat WC, Glorioso JC. 164. HSV-1 Vector-Based Assay To Identify Inhibitors of the Vanilloid Receptor Molecular Therapy. 13: S63-S64. DOI: 10.1016/J.Ymthe.2006.08.187  0.306
2005 Syme CA, Friedman PA, Bisello A. Parathyroid hormone receptor trafficking contributes to the activation of extracellular signal-regulated kinases but is not required for regulation of cAMP signaling. The Journal of Biological Chemistry. 280: 11281-8. PMID 15611080 DOI: 10.1074/Jbc.M413393200  0.361
2004 Friedman PA. PTH revisited. Kidney International. Supplement. S13-9. PMID 15461696 DOI: 10.1111/J.1523-1755.2004.09103.X  0.414
2004 Ba J, Friedman PA. Calcium-sensing receptor regulation of renal mineral ion transport. Cell Calcium. 35: 229-37. PMID 15200146 DOI: 10.1016/J.Ceca.2003.10.016  0.358
2004 Sneddon WB, Magyar CE, Willick GE, Syme CA, Galbiati F, Bisello A, Friedman PA. Ligand-selective dissociation of activation and internalization of the parathyroid hormone (PTH) receptor: conditional efficacy of PTH peptide fragments. Endocrinology. 145: 2815-23. PMID 15016722 DOI: 10.1210/En.2003-1185  0.404
2003 Ba J, Brown D, Friedman PA. Calcium-sensing receptor regulation of PTH-inhibitable proximal tubule phosphate transport. American Journal of Physiology. Renal Physiology. 285: F1233-43. PMID 12952858 DOI: 10.1152/Ajprenal.00249.2003  0.395
2003 Sneddon WB, Syme CA, Bisello A, Magyar CE, Rochdi MD, Parent JL, Weinman EJ, Abou-Samra AB, Friedman PA. Activation-independent parathyroid hormone receptor internalization is regulated by NHERF1 (EBP50). The Journal of Biological Chemistry. 278: 43787-96. PMID 12920119 DOI: 10.1074/Jbc.M306019200  0.442
2002 Magyar CE, White KE, Rojas R, Apodaca G, Friedman PA. Plasma membrane Ca2+-ATPase and NCX1 Na+/Ca2+ exchanger expression in distal convoluted tubule cells. American Journal of Physiology. Renal Physiology. 283: F29-40. PMID 12060584 DOI: 10.1152/Ajprenal.00252.2000  0.324
2001 Clemens TL, Cormier S, Eichinger A, Endlich K, Fiaschi-Taesch N, Fischer E, Friedman PA, Karaplis AC, Massfelder T, Rossert J, Schlüter KD, Silve C, Stewart AF, Takane K, Helwig JJ. Parathyroid hormone-related protein and its receptors: Nuclear functions and roles in the renal and cardiovascular systems, the placental trophoblasts and the pancreatic islets British Journal of Pharmacology. 134: 1113-1136. PMID 11704631 DOI: 10.1038/Sj.Bjp.0704378  0.397
2000 Sneddon WB, Liu F, Gesek FA, Friedman PA. Obligate mitogen-activated protein kinase activation in parathyroid hormone stimulation of calcium transport but not calcium signaling Endocrinology. 141: 4185-4193. PMID 11089552 DOI: 10.1210/Endo.141.11.7792  0.379
2000 Friedman PA. Mechanisms of renal calcium transport Experimental Nephrology. 8: 343-350. PMID 11014931 DOI: 10.1159/000020688  0.334
1999 Friedman PA. Calcium transport in the kidney Current Opinion in Nephrology and Hypertension. 8: 589-595. PMID 10541222 DOI: 10.1097/00041552-199909000-00010  0.338
1999 Friedman PA, Gesek FA, Morley P, Whitfield JF, Willick GE. Cell-specific signaling and structure-activity relations of parathyroid hormone analogs in mouse kidney cells Endocrinology. 140: 301-309. PMID 9886839 DOI: 10.1210/Endo.140.1.6462  0.409
1998 Sneddon WB, Barry ELR, Coutermarsh BA, Gesek FA, Liu F, Friedman PA. Regulation of renal parathyroid hormone receptor expression by 1,25- dihydroxyvitamin D3 and retinoic acid Cellular Physiology and Biochemistry. 8: 261-277. PMID 9792954 DOI: 10.1159/000016288  0.339
1998 White KE, Gesek FA, Reilly RF, Friedman PA. NCX1 Na/Ca exchanger inhibition by antisense oligonucleotides in mouse distal convoluted tubule cells Kidney International. 54: 897-906. PMID 9734614 DOI: 10.1046/J.1523-1755.1998.00056.X  0.314
1991 Pizzonia JH, Gesek FA, Kennedy SM, Coutermarsh BA, Bacskai BJ, Friedman PA. Immunomagnetic separation, primary culture, and characterization of cortical thick ascending limb plus distal convoluted tubule cells from mouse kidney. In Vitro Cellular & Developmental Biology : Journal of the Tissue Culture Association. 27: 409-16. PMID 1649164 DOI: 10.1007/Bf02630961  0.507
1990 Bacskai BJ, Friedman PA. Activation of latent Ca2+ channels in renal epithelial cells by parathyroid hormone. Nature. 347: 388-91. PMID 1699128 DOI: 10.1038/347388A0  0.5
1977 Friedman PA, Roch-Ramel F. Hemodynamic and natriuretic effects of bumetanide and furosemide in the cat. The Journal of Pharmacology and Experimental Therapeutics. 203: 82-91. PMID 909060  0.528
1977 Friedman PA, Roch-Ramel F. Micropuncture study of fluid handling in the cat kidney. PflüGers Archiv : European Journal of Physiology. 372: 239-42. PMID 564046 DOI: 10.1007/BF01063858  0.532
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