Thomas C Sparks - Publications

Affiliations: 
Dow AgroSciences 
Area:
Insecticide discovery, resistance, mode of action, biochemistry

50 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Sparks TC, Crouse GD, Benko Z, Demeter D, Giampietro NC, Lambert W, Brown AV. The Spinosyns, Spinosad, Spinetoram, and Synthetic Spinosyn Mimics - Discovery, Exploration, and Evolution of a Natural Product Chemistry and the Impact of Computational Tools. Pest Management Science. PMID 32893433 DOI: 10.1002/Ps.6073  0.334
2020 Sparks TC, Crossthwaite AJ, Nauen R, Banba S, Cordova D, Earley F, Ebbinghaus-Kintscher U, Fujioka S, Hirao A, Karmon D, Kennedy R, Nakao T, Popham HJR, Salgado V, Watson GB, et al. Insecticides, biologics and nematicides: Updates to IRAC's mode of action classification - a tool for resistance management. Pesticide Biochemistry and Physiology. 167: 104587. PMID 32527435 DOI: 10.1016/J.Pestbp.2020.104587  0.344
2020 Mezei I, Bielza P, Siebert MW, Torne M, Gomez LE, Valverde-Garcia P, Belando A, Moreno I, Grávalos C, Cifuentes D, Sparks TC. Sulfoxaflor efficacy in the laboratory against imidacloprid-resistant and susceptible populations of the green peach aphid, Myzus persicae: Impact of the R81T mutation in the nicotinic acetylcholine receptor. Pesticide Biochemistry and Physiology. 166: 104582. PMID 32448428 DOI: 10.1016/J.Pestbp.2020.104582  0.319
2019 Sparks TC, Wessels FJ, Lorsbach BA, Nugent BM, Watson GB. The new age of insecticide discovery-the crop protection industry and the impact of natural products. Pesticide Biochemistry and Physiology. 161: 12-22. PMID 31685191 DOI: 10.1016/J.Pestbp.2019.09.002  0.343
2019 Lorsbach BA, Sparks TC, Cicchillo RM, Garizi NV, Hahn DR, Meyer KG. Natural Products: A Strategic Lead Generation Approach in Crop Protection Discovery. Pest Management Science. PMID 30672097 DOI: 10.1002/Ps.5350  0.304
2018 Sparks TC, Hunter JE, Lorsbach BA, Hanger G, Gast R, Kemmitt G, Bryant RJ. Crop Protection Discovery - Is Being the First Best? Journal of Agricultural and Food Chemistry. PMID 30205003 DOI: 10.1021/Acs.Jafc.8B03484  0.306
2018 Zhang Y, Lorsbach B, Castetter S, Lambert WT, Kister J, Wang NX, Klittich C, Roth J, Sparks TC, Loso MR. Physicochemical Property Guidelines for Modern Agrochemicals. Pest Management Science. PMID 29667318 DOI: 10.1002/Ps.5037  0.321
2018 Crouse GD, Demeter DA, Samaritoni G, McLeod CL, Sparks TC. De Novo Design of Potent, Insecticidal Synthetic Mimics of the Spinosyn Macrolide Natural Products. Scientific Reports. 8: 4861. PMID 29559660 DOI: 10.1038/S41598-018-22894-6  0.361
2016 Sparks TC, Lorsbach BA. Perspectives on the Agrochemical Industry and Agrochemical Discovery. Pest Management Science. PMID 27753242 DOI: 10.1002/Ps.4457  0.306
2016 Dent WH, Pobanz MA, Geng C, Sparks TC, Watson GB, Letherer TJ, Beavers KW, Young CD, Adelfinskaya YA, Ross RR, Whiteker G, Renga J. Discovery of the aryl heterocyclic amine (AHA) insecticides: Synthesis, insecticidal activity, field results, mode of action and bioavailability of a leading field candidate. Pest Management Science. PMID 27607882 DOI: 10.1002/Ps.4431  0.321
2016 Lambert WT, Goldsmith ME, Sparks TC. Insecticidal Activity of Novel Thioureas and Isothioureas. Pest Management Science. PMID 27391046 DOI: 10.1002/Ps.4353  0.314
2016 Galm U, Sparks TC. Natural product derived insecticides: discovery and development of spinetoram. Journal of Industrial Microbiology & Biotechnology. 43: 185-93. PMID 26582335 DOI: 10.1007/S10295-015-1710-X  0.306
2015 Loso MR, Benko Z, Buysse A, Johnson TC, Nugent BM, Rogers RB, Sparks TC, Wang NX, Watson GB, Zhu Y. SAR studies directed toward the pyridine moiety of the sap-feeding insecticide sulfoxaflor (Isoclast™ active). Bioorganic & Medicinal Chemistry. PMID 26706115 DOI: 10.1016/J.Bmc.2015.11.022  0.353
2015 Sparks TC, Nauen R. IRAC: Mode of action classification and insecticide resistance management Pesticide Biochemistry and Physiology. 121: 122-128. PMID 26047120 DOI: 10.1016/J.Pestbp.2014.11.014  0.331
2013 Sparks TC. Insecticide discovery: an evaluation and analysis. Pesticide Biochemistry and Physiology. 107: 8-17. PMID 25149229 DOI: 10.1016/J.Pestbp.2013.05.012  0.345
2013 Sparks TC, Watson GB, Loso MR, Geng C, Babcock JM, Thomas JD. Sulfoxaflor and the sulfoximine insecticides: chemistry, mode of action and basis for efficacy on resistant insects. Pesticide Biochemistry and Physiology. 107: 1-7. PMID 25149228 DOI: 10.1016/J.Pestbp.2013.05.014  0.355
2013 Longhurst C, Babcock JM, Denholm I, Gorman K, Thomas JD, Sparks TC. Cross-resistance relationships of the sulfoximine insecticide sulfoxaflor with neonicotinoids and other insecticides in the whiteflies Bemisia tabaci and Trialeurodes vaporariorum. Pest Management Science. 69: 809-13. PMID 23203347 DOI: 10.1002/Ps.3439  0.333
2013 Geng C, Watson GB, Sparks TC. Nicotinic Acetylcholine Receptors as Spinosyn Targets for Insect Pest Management Advances in Insect Physiology. 44: 101-210. DOI: 10.1016/B978-0-12-394389-7.00003-X  0.346
2012 Sparks TC, DeBoer GJ, Wang NX, Hasler JM, Loso MR, Watson GB. Differential metabolism of sulfoximine and neonicotinoid insecticides by Drosophila melanogaster monooxygenase CYP6G1 Pesticide Biochemistry and Physiology. 103: 159-165. DOI: 10.1016/J.Pestbp.2012.05.006  0.342
2012 Sparks TC, Dripps JE, Watson GB, Paroonagian D. Resistance and cross-resistance to the spinosyns - A review and analysis Pesticide Biochemistry and Physiology. 102: 1-10. DOI: 10.1016/J.Pestbp.2011.11.004  0.305
2012 Perry T, Chan JQ, Batterham P, Watson GB, Geng C, Sparks TC. Effects of mutations in Drosophila nicotinic acetylcholine receptor subunits on sensitivity to insecticides targeting nicotinic acetylcholine receptors Pesticide Biochemistry and Physiology. 102: 56-60. DOI: 10.1016/J.Pestbp.2011.10.010  0.319
2011 Babcock JM, Gerwick CB, Huang JX, Loso MR, Nakamura G, Nolting SP, Rogers RB, Sparks TC, Thomas J, Watson GB, Zhu Y. Biological characterization of sulfoxaflor, a novel insecticide. Pest Management Science. 67: 328-34. PMID 21308958 DOI: 10.1002/Ps.2069  0.345
2011 Watson GB, Loso MR, Babcock JM, Hasler JM, Letherer TJ, Young CD, Zhu Y, Casida JE, Sparks TC. Novel nicotinic action of the sulfoximine insecticide sulfoxaflor. Insect Biochemistry and Molecular Biology. 41: 432-9. PMID 21296156 DOI: 10.1016/J.Ibmb.2011.01.009  0.465
2011 Zhu Y, Loso MR, Watson GB, Sparks TC, Rogers RB, Huang JX, Gerwick BC, Babcock JM, Kelley D, Hegde VB, Nugent BM, Renga JM, Denholm I, Gorman K, DeBoer GJ, et al. Discovery and characterization of sulfoxaflor, a novel insecticide targeting sap-feeding pests. Journal of Agricultural and Food Chemistry. 59: 2950-7. PMID 21105655 DOI: 10.1021/Jf102765X  0.387
2010 Watson GB, Chouinard SW, Cook KR, Geng C, Gifford JM, Gustafson GD, Hasler JM, Larrinua IM, Letherer TJ, Mitchell JC, Pak WL, Salgado VL, Sparks TC, Stilwell GE. A spinosyn-sensitive Drosophila melanogaster nicotinic acetylcholine receptor identified through chemically induced target site resistance, resistance gene identification, and heterologous expression. Insect Biochemistry and Molecular Biology. 40: 376-84. PMID 19944756 DOI: 10.1016/J.Ibmb.2009.11.004  0.308
2010 Roe RM, Young HP, Iwasa T, Wyss CF, Stumpf CF, Sparks TC, Watson GB, Sheets JJ, Thompson GD. Mechanism of resistance to spinosyn in the tobacco budworm, Heliothis virescens Pesticide Biochemistry and Physiology. 96: 8-13. DOI: 10.1016/J.Pestbp.2009.08.009  0.316
2009 Lewer P, Hahn DR, Karr LL, Duebelbeis DO, Gilbert JR, Crouse GD, Worden T, Sparks TC, Edwards PM, Graupner PR. Discovery of the butenyl-spinosyn insecticides: novel macrolides from the new bacterial strain Saccharopolyspora pogona. Bioorganic & Medicinal Chemistry. 17: 4185-96. PMID 19324553 DOI: 10.1016/J.Bmc.2009.02.035  0.31
2008 Sparks TC, Crouse GD, Dripps JE, Anzeveno P, Martynow J, Deamicis CV, Gifford J. Neural network-based QSAR and insecticide discovery: spinetoram. Journal of Computer-Aided Molecular Design. 22: 393-401. PMID 18344004 DOI: 10.1007/S10822-008-9205-8  0.336
2007 Stumpf CF, Comins DL, Sparks TC, Donohue KV, Roe RM. Insecticidal activity and mode of action of novel nicotinoids synthesized by new acylpyridinium salt chemistry and directed lithiation Pesticide Biochemistry and Physiology. 87: 211-219. DOI: 10.1016/J.Pestbp.2006.07.012  0.338
2006 Sheehan LS, Lill RE, Wilkinson B, Sheridan RM, Vousden WA, Kaja AL, Crouse GD, Gifford J, Graupner PR, Karr L, Lewer P, Sparks TC, Leadlay PF, Waldron C, Martin CJ. Engineering of the spinosyn PKS: directing starter unit incorporation. Journal of Natural Products. 69: 1702-10. PMID 17190446 DOI: 10.1021/Np0602517  0.321
2001 Sparks TC, Crouse GD, Durst G. Natural products as insecticides: the biology, biochemistry and quantitative structure-activity relationships of spinosyns and spinosoids. Pest Management Science. 57: 896-905. PMID 11695182 DOI: 10.1002/Ps.358  0.37
2001 Crouse GD, Sparks TC, Schoonover J, Gifford J, Dripps J, Bruce T, Larson LL, Garlich J, Hatton C, Hill RL, Worden TV, Martynow JG. Recent advances in the chemistry of spinosyns. Pest Management Science. 57: 177-85. PMID 11455648 DOI: 10.1002/1526-4998(200102)57:2<177::Aid-Ps281>3.0.Co;2-Z  0.339
2000 Sparks TC, Anzeveno PB, Martynow JG, Gifford JM, Hertlein MB, Worden TV, Kirst HA. The Application of Artificial Neural Networks to the Identification of New Spinosoids with Improved Biological Activity toward Larvae of Heliothis virescens Pesticide Biochemistry and Physiology. 67: 187-197. DOI: 10.1006/Pest.2000.2490  0.309
1998 Sparks TC, Thompson GD, Kirst HA, Hertlein MB, Larson LL, Worden TV, Thibault ST. Biological Activity of the Spinosyns, New Fermentation Derived Insect Control Agents, on Tobacco Budworm (Lepidoptera: Noctuidae) Larvae Journal of Economic Entomology. 91: 1277-1283. DOI: 10.1093/Jee/91.6.1277  0.339
1993 Sparks TC, Leonard RB, Schneider F, Graves JB. Ovicidal activity and alteration of octopamine titers : effects of selected insecticides on eggs of the tobacco budworm (Lepidoptera:Noctuidae) Journal of Economic Entomology. 86: 294-300. DOI: 10.1093/Jee/86.2.294  0.307
1983 Dowd PF, Smith MC, Sparks TC. Influence of Soybean Leaf Extracts on Ester Cleavage in Cabbage and Soybean Loopers (Lepidoptera: Noctuidae) Journal of Economic Entomology. 76: 700-703. DOI: 10.1093/Jee/76.4.700  0.323
1983 Roe RM, Hammond AM, Sparks TC. Characterization of the plasma juvenile hormone esterase in synchronous last stadium female larvae of the sugar cane borer, Diatraea saccharalis (F.) Insect Biochemistry. 13: 163-170. DOI: 10.1016/0020-1790(83)90079-3  0.315
1983 Sparks TC, Rose RL. Inhibition and substrate specificity of the haemolymph juvenile hormone esterase of the cabbage looper, Trichoplusia ni (Hübner) Insect Biochemistry. 13: 633-640. DOI: 10.1016/0020-1790(83)90037-9  0.348
1982 Hammock BD, Wing KD, McLaughlin J, Lovell VM, Sparks TC. Trifluoromethylketones as possible transition state analog inhibitors of juvenile hormone esterase Pesticide Biochemistry and Physiology. 17: 76-88. DOI: 10.1016/0048-3575(82)90128-6  0.428
1981 Wing KD, Sparks TC, Lovell VM, Levinson SO, Hammock BD. The distribution of juvenile hormone esterase and its interrelationship with other proteins influencing juvenile hormone metabolism in the cabbage looper, Trichoplusia ni Insect Biochemistry. 11: 473-485. DOI: 10.1016/0020-1790(81)90083-4  0.448
1980 Sparks TC, Hammock BD. Comparative inhibition of the juvenile hormone esterases from Trichoplusia ni, Tenebrio molitor, and Musca domestica Pesticide Biochemistry and Physiology. 14: 290-302. DOI: 10.1016/0048-3575(80)90037-1  0.455
1979 Sparks TC, Wing KD, Hammock BD. Effects of the anti hormone-hormone mimic ETB on the induction of insect juvenile hormone esterase in Trichoplusia ni. Life Sciences. 25: 445-50. PMID 225631 DOI: 10.1016/0024-3205(79)90577-0  0.437
1979 Mumby SM, Hammock BD, Sparks TC, Ota K. Synthesis and bioassay of carbamate inhibitors of the juvenile hormone hydrolyzing esterases from the housefly, Musca domestica Journal of Agricultural and Food Chemistry. 27: 763-765. DOI: 10.1021/Jf60224A021  0.435
1979 Hammock BD, Sparks TC, Mumby SM, Lovell VM, Wing KD, Gill SS. Comparative Biochemical Mechanisms Of Juvenile Hormone And Juvenoid Degradation In Insects And Mammals Advances in Pesticide Scienceabstract and Addendum. DOI: 10.1016/B978-0-08-023930-9.50314-2  0.415
1979 Quistad GB, Staiger LE, Schooley DA, Sparks TC, Hammock BD. The possible role of carnitine in the selective toxicity of the miticide cycloprate Pesticide Biochemistry and Physiology. 11: 159-165. DOI: 10.1016/0048-3575(79)90055-5  0.411
1979 Sparks TC, Willis WS, Shorey HH, Hammock BD. Haemolymph juvenile hormone esterase activity in synchronous last instar larvae of the cabbage looper, Trichoplusia ni Journal of Insect Physiology. 25: 125-132. DOI: 10.1016/0022-1910(79)90090-8  0.447
1979 Sparks TC, Hammock BD. Induction and regulation of juvenile hormone esterases during the last larval instar of the cabbage looper, Trichoplusia ni Journal of Insect Physiology. 25: 551-560. DOI: 10.1016/0022-1910(79)90069-6  0.44
1979 Sparks TC, Hammock BD. A comparison of the induced and naturally occurring juvenile hormone esterases from last instar larvae of Trichoplusia ni Insect Biochemistry. 9: 411-421. DOI: 10.1016/0020-1790(79)90091-X  0.483
1977 Hammock BD, Sparks TC. A rapid assay for insect juvenile hormone esterase activity. Analytical Biochemistry. 82: 573-9. PMID 907152 DOI: 10.1016/0003-2697(77)90196-8  0.433
1977 Hammock BD, Sparks TC, Mumby SM. Selective inhibition of JH esterases from cockroach hemolymph Pesticide Biochemistry and Physiology. 7: 517-530. DOI: 10.1016/0048-3575(77)90046-3  0.456
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