| Year |
Citation |
Score |
| 2024 |
Anderson M, Carton T, Salvini C, Crawford J, Pairaudeau G, Waring MJ. Micelle-Promoted Reductive Amination of DNA-Conjugated Amines for DNA-Encoded Library Synthesis. Chemistry (Weinheim An Der Bergstrasse, Germany). e202400239. PMID 38251309 DOI: 10.1002/chem.202400239 |
0.661 |
|
| 2023 |
Salvini CLA, Darlot B, Davison J, Martin MP, Tudhope SJ, Turberville S, Kawamura A, Noble MEM, Wedge SR, Crawford JJ, Waring MJ. Fragment expansion with NUDELs - poised DNA-encoded libraries. Chemical Science. 14: 8288-8294. PMID 37564419 DOI: 10.1039/d3sc01171b |
0.635 |
|
| 2023 |
Graham J, Stanway-Gordon H, Waring MJ. Micelle-Mediated Sonogashira Coupling for DNA-Encoded Library Synthesis. Chemistry (Weinheim An Der Bergstrasse, Germany). e202300603. PMID 37184619 DOI: 10.1002/chem.202300603 |
0.362 |
|
| 2023 |
Stanway-Gordon HA, Odger JA, Waring MJ. Development of a Micellar-Promoted Heck Reaction for the Synthesis of DNA-Encoded Libraries. Bioconjugate Chemistry. PMID 36883323 DOI: 10.1021/acs.bioconjchem.3c00051 |
0.383 |
|
| 2022 |
Castan IFSF, Madin A, Pairaudeau G, Waring MJ. Scope of on-DNA nucleophilic aromatic substitution on weakly-activated heterocyclic substrates for the synthesis of DNA-encoded libraries. Bioorganic & Medicinal Chemistry. 63: 116688. PMID 35430536 DOI: 10.1016/j.bmc.2022.116688 |
0.396 |
|
| 2021 |
Hunter JH, Potowski M, Stanway-Gordon HA, Madin A, Pairaudeau G, Brunschweiger A, Waring MJ. Functional Group Tolerance of a Micellar on-DNA Suzuki-Miyaura Cross-Coupling Reaction for DNA-Encoded Library Design. The Journal of Organic Chemistry. PMID 34816720 DOI: 10.1021/acs.joc.1c02259 |
0.32 |
|
| 2021 |
Graham JS, Hunter JH, Waring MJ. Micellar Buchwald-Hartwig Coupling of Aryl and Heteroarylamines for the Synthesis of DNA-Encoded Libraries. The Journal of Organic Chemistry. PMID 34788051 DOI: 10.1021/acs.joc.1c02325 |
0.383 |
|
| 2021 |
Stanway-Gordon HA, Graham JS, Waring MJ. On-DNA Transfer Hydrogenolysis and Hydrogenation for the Synthesis of DNA-Encoded Chemical Libraries. Angewandte Chemie (International Ed. in English). PMID 34748693 DOI: 10.1002/anie.202111927 |
0.39 |
|
| 2021 |
Hunter JH, Anderson MJ, Castan IFSF, Graham JS, Salvini CLA, Stanway-Gordon HA, Crawford JJ, Madin A, Pairaudeau G, Waring MJ. Highly efficient on-DNA amide couplings promoted by micelle forming surfactants for the synthesis of DNA encoded libraries. Chemical Science. 12: 9475-9484. PMID 34349922 DOI: 10.1039/d1sc03007h |
0.67 |
|
| 2020 |
McAulay K, Hoyt EA, Thomas M, Schimpl M, Bodnarchuk MS, Lewis HJ, Barratt D, Bhavsar D, Robinson DM, Deery MJ, Ogg D, Bernardes GJL, Ward RA, Waring MJ, Kettle JG. Alkynyl Benzoxazines and Dihydroquinazolines as Cysteine Targeting Covalent Warheads and Their Application in Identification of Selective Irreversible Kinase Inhibitors. Journal of the American Chemical Society. PMID 32412754 DOI: 10.1021/Jacs.9B13391 |
0.35 |
|
| 2019 |
Hunter JH, Prendergast L, Valente LF, Madin A, Pairaudeau G, Waring MJ. High fidelity Suzuki-Miyaura coupling for the synthesis of DNA encoded libraries enabled by micelle forming surfactants. Bioconjugate Chemistry. PMID 31873005 DOI: 10.1021/Acs.Bioconjchem.9B00838 |
0.475 |
|
| 2019 |
Bosma R, Wang Z, Kooistra AJ, Bushby N, Kuhne S, van den Bor J, Waring MJ, de Graaf C, de Esch IJ, Vischer HF, Sheppard RJ, Wijtmans M, Leurs R. Route to Prolonged Residence Time at the Histamine H Receptor: Growing from Desloratadine to Rupatadine. Journal of Medicinal Chemistry. PMID 31274307 DOI: 10.1021/Acs.Jmedchem.9B00447 |
0.304 |
|
| 2019 |
Wood D, Lopez-Fernandez JD, Knight L, Al-Khawaldeh I, Gai C, Lin S, Martin MP, Miller D, Cano C, Endicott J, Hardcastle I, Noble M, Waring MJ. FragLites - minimal, halogenated fragments displaying pharmacophore doublets. An efficient approach to druggability assessment and hit generation. Journal of Medicinal Chemistry. PMID 30860382 DOI: 10.1021/Acs.Jmedchem.9B00304 |
0.322 |
|
| 2017 |
Xia L, de Vries H, Lenselink EB, Louvel J, Waring MJ, Cheng L, Pahlén S, Petersson MJ, Schell P, Olsson RI, Heitman LH, Sheppard RJ, IJzerman AP. Structure-affinity Relationships and Structure-kinetic Relationships of 1,2-Diarylimidazol-4-carboxamide Derivatives as Human Cannabinoid 1 Receptor Antagonists. Journal of Medicinal Chemistry. PMID 29111736 DOI: 10.1021/Acs.Jmedchem.7B00861 |
0.307 |
|
| 2016 |
Waring MJ, Chen H, Rabow AA, Walker G, Bobby R, Boiko S, Bradbury RH, Callis R, Clark E, Dale I, Daniels DL, Dulak A, Flavell L, Holdgate G, Jowitt TA, et al. Potent and selective bivalent inhibitors of BET bromodomains. Nature Chemical Biology. PMID 27775716 DOI: 10.1038/Nchembio.2210 |
0.323 |
|
| 2016 |
Bradbury RH, Callis R, Carr GR, Chen H, Clark E, Feron L, Glossop SC, Graham MA, Hattersley M, Jones C, Lamont SG, Ouvry G, Patel A, Patel J, Rabow AA, ... ... Waring MJ, et al. Optimisation of a series of bivalent triazolopyridazine based bromodomain and extraterminal inhibitors: the discovery of (3R)-4-[2-[4-[1-(3-methoxy-[1,2,4]triazolo[4,3-b]pyridazin-6-yl)-4-piperidyl]phenoxy]ethyl]-1,3-dimethyl-piperazin-2-one (AZD5153). Journal of Medicinal Chemistry. PMID 27528113 DOI: 10.1021/Acs.Jmedchem.6B00070 |
0.306 |
|
| 2015 |
Sheh L, Waring MJ. Editorial: Potential Therapeutic Agents based on DNA Sequence- Selective Binding Substances. Current Topics in Medicinal Chemistry. 15: 1291-2. PMID 25869486 DOI: 10.2174/1568026615666150414104747 |
0.389 |
|
| 2015 |
Waring MJ, Bennett SNL, Campbell L, Hallam S, Martin NG, Tickner C. A safe and scalable synthesis of 2-hydroxy-3-alkoxypropionates by epoxide ring opening Tetrahedron Letters. 56: 4904-4907. DOI: 10.1016/J.Tetlet.2015.06.080 |
0.383 |
|
| 2014 |
Yang RC, Huang JT, Chen YL, Hung CC, Liao M, Yao WC, Chen CH, Liou CC, Waring MJ, Sheh L. Enthalpy-driven nuclease-like activity and mechanism of peptide-chlorambucil conjugates. Organic & Biomolecular Chemistry. 12: 4890-904. PMID 24874710 DOI: 10.1039/C4Ob00123K |
0.307 |
|
| 2013 |
Plowright AT, Barton P, Bennett S, Birch AM, Birtles S, Buckett LK, Butlin RJ, Davies RDM, Ertan A, Gutierrez PM, Kemmitt PD, Leach AG, Svensson PH, Turnbull AV, Waring MJ. Design and synthesis of a novel series of cyclohexyloxy-pyridyl derivatives as inhibitors of diacylglycerol acyl transferase 1 Medchemcomm. 4: 151-158. DOI: 10.1039/C2Md20187A |
0.317 |
|
| 2010 |
Tetlow DJ, Hennecke U, Raftery J, Waring MJ, Clarke DS, Clayden J. Sequential double α-arylation of N-allylureas by asymmetric deprotonation and N→C aryl migration. Organic Letters. 12: 5442-5. PMID 21062018 DOI: 10.1021/Ol102155H |
0.31 |
|
| 2008 |
Clark JS, Northall JM, Marlin F, Nay B, Wilson C, Blake AJ, Waring MJ. Synthetic studies on the cornexistins: synthesis of (+/-)-5-epi-hydroxycornexistin. Organic & Biomolecular Chemistry. 6: 4012-25. PMID 18931810 DOI: 10.1039/B811245B |
0.318 |
|
| 2008 |
Boyd S, Campbell L, Liao W, Meng Q, Peng Z, Wang X, Waring MJ. A one step synthesis of 1-alkylpyrazolo[5,4-d]pyrimidines Tetrahedron Letters. 49: 7395-7397. DOI: 10.1016/J.Tetlet.2008.10.065 |
0.329 |
|
| 2007 |
Van Vliet LD, Ellis T, Foley PJ, Liu L, Pfeffer FM, Russell RA, Warrener RN, Hollfelder F, Waring MJ. Molecular recognition of DNA by rigid [N]-polynorbornane-derived bifunctional intercalators: synthesis and evaluation of their binding properties. Journal of Medicinal Chemistry. 50: 2326-40. PMID 17429957 DOI: 10.1021/Jm0613020 |
0.443 |
|
| 2006 |
Wells G, Martin CRH, Howard PW, Sands ZA, Laughton CA, Tiberghien A, Woo CK, Masterson LA, Stephenson MJ, Hartley JA, Jenkins TC, Shnyder SD, Loadman PM, Waring MJ, Thurston DE. Design, synthesis, and biophysical and biological evaluation of a series of pyrrolobenzodiazepine-poly(N-methylpyrrole) conjugates Journal of Medicinal Chemistry. 49: 5442-5461. PMID 16942018 DOI: 10.1021/Jm051199Z |
0.419 |
|
| 2005 |
Urbach AR, Waring MJ. Visualising DNA: footprinting and 1-2D gels. Molecular Biosystems. 1: 287-93. PMID 16880993 DOI: 10.1039/B509471M |
0.3 |
|
| 2005 |
Martin C, Ellis T, McGurk CJ, Jenkins TC, Hartley JA, Waring MJ, Thurston DE. Sequence-selective interaction of the minor-groove interstrand cross-linking agent SJG-136 with naked and cellular DNA: footprinting and enzyme inhibition studies. Biochemistry. 44: 4135-47. PMID 15766241 DOI: 10.1021/Bi0479813 |
0.414 |
|
| 2005 |
Tseng YD, Ge H, Wang X, Edwardson JM, Waring MJ, Fitzgerald WJ, Henderson RM. Atomic force microscopy study of the structural effects induced by echinomycin binding to DNA. Journal of Molecular Biology. 345: 745-58. PMID 15588823 DOI: 10.1016/J.Jmb.2004.10.059 |
0.311 |
|
| 2005 |
Bailly C, Kluza J, Martin C, Ellis T, Waring MJ. DNase I footprinting of small molecule binding sites on DNA. Methods in Molecular Biology (Clifton, N.J.). 288: 319-42. PMID 15333913 DOI: 10.1385/1-59259-823-4:319 |
0.329 |
|
| 2004 |
Virstedt J, Berge T, Henderson RM, Waring MJ, Travers AA. The influence of DNA stiffness upon nucleosome formation. Journal of Structural Biology. 148: 66-85. PMID 15363788 DOI: 10.1016/J.Jsb.2004.03.007 |
0.329 |
|
| 2004 |
Paz MM, Kumar GS, Glover M, Waring MJ, Tomasz M. Mitomycin dimers: polyfunctional cross-linkers of DNA. Journal of Medicinal Chemistry. 47: 3308-19. PMID 15163210 DOI: 10.1021/Jm049863J |
0.405 |
|
| 2004 |
May LG, Madine MA, Waring MJ. Echinomycin inhibits chromosomal DNA replication and embryonic development in vertebrates. Nucleic Acids Research. 32: 65-72. PMID 14704344 DOI: 10.1093/Nar/Gkh166 |
0.398 |
|
| 2003 |
Leng F, Chaires JB, Waring MJ. Energetics of echinomycin binding to DNA Nucleic Acids Research. 31: 6191-6197. PMID 14576305 DOI: 10.1093/Nar/Gkg826 |
0.41 |
|
| 2003 |
Donohoe TJ, Mitchell L, Waring MJ, Helliwell M, Bell A, Newcombe NJ. Scope of the directed dihydroxylation: application to cyclic homoallylic alcohols and trihaloacetamides. Organic & Biomolecular Chemistry. 1: 2173-86. PMID 12945911 DOI: 10.1039/B303081D |
0.664 |
|
| 2003 |
Berge T, Haken EL, Waring MJ, Henderson RM. The binding mode of the DNA bisintercalator luzopeptin investigated using atomic force microscopy. Journal of Structural Biology. 142: 241-6. PMID 12713951 DOI: 10.1016/S1047-8477(03)00015-7 |
0.304 |
|
| 2002 |
Carrasco C, Rosu F, Gabelica V, Houssier C, De Pauw E, Garbay-Jaureguiberry C, Roques B, David Wilson W, Chaires JB, Waring MJ, Bailly C. Tight binding of the antitumor drug ditercalinium to quadruplex DNA Chembiochem. 3: 1235-1241. PMID 12465032 DOI: 10.1002/1439-7633(20021202)3:12<1235::Aid-Cbic1235>3.0.Co;2-I |
0.318 |
|
| 2002 |
Donohoe TJ, Blades K, Moore PR, Waring MJ, Winter JJ, Helliwell M, Newcombe NJ, Stemp G. Directed dihydroxylation of cyclic allylic alcohols and trichloroacetamides using OsO4/TMEDA. The Journal of Organic Chemistry. 67: 7946-56. PMID 12423122 DOI: 10.1021/Jo026161Y |
0.662 |
|
| 2002 |
Crow SD, Bailly C, Garbay-Jaureguiberry C, Roques B, Shaw BR, Waring MJ. DNA sequence recognition by the antitumor drug ditercalinium. Biochemistry. 41: 8672-82. PMID 12093285 DOI: 10.1021/Bi012207Q |
0.456 |
|
| 2002 |
Berge T, Jenkins NS, Hopkirk RB, Waring MJ, Edwardson JM, Henderson RM. Structural perturbations in DNA caused by bis-intercalation of ditercalinium visualised by atomic force microscopy. Nucleic Acids Research. 30: 2980-6. PMID 12087184 DOI: 10.1093/Nar/Gkf409 |
0.314 |
|
| 2002 |
Ji YH, Bur D, Häsler W, Runtz Schmitt V, Dorn A, Bailly C, Waring MJ, Hochstrasser R, Leupin W. Tris-benzimidazole derivatives: design, synthesis and DNA sequence recognition. Bioorganic & Medicinal Chemistry. 9: 2905-19. PMID 11597472 DOI: 10.1016/S0968-0896(01)00170-5 |
0.338 |
|
| 2001 |
Minnock A, Lin LS, Morgan J, Crow SD, Waring MJ, Sheh L. Sequence-specific DNA cleavage by dipeptides disubstituted with chlorambucil and 2,6-dimethoxyhydroquinone-3-mercaptoacetic acid. Bioconjugate Chemistry. 12: 870-82. PMID 11716676 DOI: 10.1021/Bc000151R |
0.411 |
|
| 2001 |
Fox KR, Waring MJ. High-resolution footprinting studies of drug-DNA complexes using chemical and enzymatic probes. Methods in Enzymology. 340: 412-30. PMID 11529207 DOI: 10.1016/S0076-6879(01)40434-4 |
0.322 |
|
| 2001 |
Bailly C, Waring MJ. Use of DNA molecules substituted with unnatural nucleotides to probe specific drug-DNA interactions. Methods in Enzymology. 340: 485-502. PMID 11494865 DOI: 10.1016/S0076-6879(01)40438-1 |
0.448 |
|
| 2001 |
Bailly C, Crow S, Minnock A, Waring MJ. DNA recognition by quinoline antibiotics: use of base-modified DNA molecules to investigate determinants of sequence-specific binding of luzopeptin. Nucleosides, Nucleotides & Nucleic Acids. 19: 1337-53. PMID 11097063 DOI: 10.1080/15257770008033056 |
0.454 |
|
| 2001 |
Donohoe TJ, Mitchell L, Waring MJ, Helliwell M, Bell A, Newcombe NJ. Homoallylic alcohols and trichloroacetamides as hydrogen bond donors for directed dihydroxylation Tetrahedron Letters. 42: 8951-8954. DOI: 10.1016/S0040-4039(01)01999-2 |
0.662 |
|
| 2001 |
Magnus P, Waring MJ, Ollivier C, Lynch V. Erratum to “Stereoselective synthesis of the bicyclo[5.3.0]decane portion of the diterpene antibiotic guanacastepene using a pyrylium-ylide [5+2] cycloaddition reaction” Tetrahedron Letters. 42: 6977. DOI: 10.1016/S0040-4039(01)01417-4 |
0.317 |
|
| 2001 |
Magnus P, Waring MJ, Ollivier C, Lynch V. Stereoselective synthesis of the bicyclo[5.3.0]decane portion of the diterpene antibiotic guanacastepene using a pyrylium-ylide [5+2] cycloaddition reaction Tetrahedron Letters. 42: 4947-4950. DOI: 10.1016/S0040-4039(01)00851-6 |
0.634 |
|
| 2000 |
Møllegaard NE, Bailly C, Waring MJ, Nielsen PE. Quinoxaline antibiotics enhance peptide nucleic acid binding to double-stranded DNA. Biochemistry. 39: 9502-7. PMID 10924146 DOI: 10.1021/Bi000254X |
0.444 |
|
| 2000 |
Donohoe TJ, Waring MJ, Newcombe NJ. Enhanced stereoselectivity in the catalytic dihydroxylation of acyclic allylic alcohols Synlett. 149-151. DOI: 10.1055/S-2000-6457 |
0.648 |
|
| 2000 |
Magnus P, Waring MJ, Scott DA. Conjugate reduction of α,β-unsaturated ketones using an Mn(III) catalyst, phenylsilane and isopropyl alcohol Tetrahedron Letters. 41: 9731-9733. DOI: 10.1016/S0040-4039(00)01728-7 |
0.623 |
|
| 2000 |
Magnus P, Payne AH, Waring MJ, Scott DA, Lynch V. Conversion of α,β-unsaturated ketones into α-hydroxy ketones using an Mn(III) catalyst, phenylsilane and dioxygen: Acceleration of conjugate hydride reduction by dioxygen Tetrahedron Letters. 41: 9725-9730. DOI: 10.1016/S0040-4039(00)01727-5 |
0.605 |
|
| 1999 |
Minnock A, Crow S, Bailly C, Waring MJ. The influence of the exocyclic pyrimidine 5-methyl group on DNAse I cleavage and sequence recognition by drugs. Biochimica Et Biophysica Acta. 1489: 233-48. PMID 10673026 DOI: 10.1016/S0167-4781(99)00188-8 |
0.309 |
|
| 1999 |
Bailly C, Crow S, Minnock A, Waring MJ. Demethylation of thymine residues affects DNA cleavage by endonucleases but not sequence recognition by drugs. Journal of Molecular Biology. 291: 561-73. PMID 10448037 DOI: 10.1006/Jmbi.1999.2979 |
0.323 |
|
| 1999 |
David-Cordonnier MH, Payet D, D'Halluin JC, Waring MJ, Travers AA, Bailly C. The DNA-binding domain of human c-Abl tyrosine kinase promotes the interaction of a HMG chromosomal protein with DNA. Nucleic Acids Research. 27: 2265-70. PMID 10325413 DOI: 10.1093/Nar/27.11.2265 |
0.303 |
|
| 1999 |
Stetor SR, Rausch JW, Guo MJ, Burnham JP, Boone LR, Waring MJ, Le Grice SF. Characterization of (+) strand initiation and termination sequences located at the center of the equine infectious anemia virus genome. Biochemistry. 38: 3656-67. PMID 10090753 DOI: 10.1021/BI982764L |
0.301 |
|
| 1999 |
Tomasz M, Das A, Tang KS, Ford MGJ, Minnock A, Musser SM, Waring MJ. The Purine-2-amino Group as the Critical Recognition Element for Sequence-Specific Alkylation and Cross-Linking of DNA by Mitomycin CJ. Am. Chem. Soc.1998,120, 11581−11593 Journal of the American Chemical Society. 121: 1112-1112. DOI: 10.1021/Ja9855388 |
0.36 |
|
| 1999 |
Donohoe TJ, Newcombe NJ, Waring MJ. syn Stereocontrol in the directed dihydroxylation of acyclic allylic alcohols Tetrahedron Letters. 40: 6881-6885. DOI: 10.1016/S0040-4039(99)01371-4 |
0.661 |
|
| 1998 |
Marchand C, Sun JS, Bailly C, Waring MJ, Garestier T, Hélène C. Optimization of alternate-strand triple helix formation at the 5'CpG3' and 5'GpC3' junction steps. Biochemistry. 37: 13322-9. PMID 9748340 DOI: 10.1021/Bi980618+ |
0.344 |
|
| 1998 |
Bailly C, Waring MJ. The use of diaminopurine to investigate structural properties of nucleic acids and molecular recognition between ligands and DNA. Nucleic Acids Research. 26: 4309-14. PMID 9742229 DOI: 10.1093/Nar/26.19.4309 |
0.331 |
|
| 1998 |
Buttinelli M, Minnock A, Panetta G, Waring M, Travers A. The exocyclic groups of DNA modulate the affinity and positioning of the histone octamer. Proceedings of the National Academy of Sciences of the United States of America. 95: 8544-9. PMID 9671714 DOI: 10.1073/Pnas.95.15.8544 |
0.437 |
|
| 1998 |
Carrasco C, Waring MJ, Bailly C. Substitution of 5-methylcytosines for cytosines enhances the stability of topoisomerase I-DNA complexes and modulates the sequence selectivity of camptothecin-induced DNA cleavage. Febs Letters. 425: 337-40. PMID 9559675 DOI: 10.1016/S0014-5793(98)00259-2 |
0.341 |
|
| 1998 |
Bailly C, Waring MJ. DNA recognition by quinoxaline antibiotics: use of base-modified DNA molecules to investigate determinants of sequence-specific binding of triostin A and TANDEM. The Biochemical Journal. 81-7. PMID 9461494 DOI: 10.1042/BJ3300081 |
0.327 |
|
| 1998 |
Bailly C, Suh D, Waring MJ, Chaires JB. Binding of daunomycin to diaminopurine- and/or inosine-substituted DNA Biochemistry. 37: 1033-1045. PMID 9454594 DOI: 10.1021/Bi9716128 |
0.428 |
|
| 1998 |
Bailly C, Colson P, Houssier C, Rodrigues-Pereira E, Prudhomme M, Waring MJ. Recognition of specific sequences in DNA by a topoisomerase I inhibitor derived from the antitumor drug rebeccamycin. Molecular Pharmacology. 53: 77-87. PMID 9443934 DOI: 10.1124/MOL.53.1.77 |
0.364 |
|
| 1998 |
Waring MJ, Bailly C. The influence of the exocyclic amino group characteristic of GC base pairs on molecular recognition of specific nucleotide sequences in DNA by berenil and DAPI. Journal of Molecular Recognition : Jmr. 10: 121-7. PMID 9408827 DOI: 10.1002/(Sici)1099-1352(199705/06)10:3<121::Aid-Jmr356>3.0.Co;2-L |
0.333 |
|
| 1998 |
Donohoe TJ, Harji RR, Moore PR, Waring MJ. Applications of stoichiometric organotransition metal complexes in organic synthesis Journal of the Chemical Society - Perkin Transactions 1. 819-834. DOI: 10.1039/A706382B |
0.617 |
|
| 1998 |
Tomasz M, Das A, Tang KS, Ford MGJ, Minnock A, Musser SM, Waring MJ. The purine 2-amino group as the critical recognition element for sequence-specific alkylation and cross-linking of DNA by mitomycin C Journal of the American Chemical Society. 120: 11581-11593. DOI: 10.1021/Ja9824019 |
0.395 |
|
| 1998 |
Donohoe TJ, Blades K, Helliwell M, Waring MJ, Newcombe NJ. The synthesis of (+)-pericosine B Tetrahedron Letters. 39: 8755-8758. DOI: 10.1016/S0040-4039(98)01989-3 |
0.65 |
|
| 1997 |
Mollegaard NE, Bailly C, Waring MJ, Nielsen PE. Effects of diaminopurine and inosine substitutions on A-tract induced DNA curvature. Importance of the 3'-A-tract junction. Nucleic Acids Research. 25: 3497-502. PMID 9254710 DOI: 10.1093/Nar/25.17.3497 |
0.319 |
|
| 1997 |
Bailly C, Perrine D, Lancelot JC, Saturnino C, Robba M, Waring MJ. Sequence-selective binding to DNA of bis(amidinophenoxy)alkanes related to propamidine and pentamidine. The Biochemical Journal. 23-31. PMID 9173886 DOI: 10.1042/Bj3230023 |
0.305 |
|
| 1997 |
Bailly C, Kénani A, Waring MJ. Altered cleavage of DNA sequences by bleomycin and its deglycosylated derivative in the presence of actinomycin. Nucleic Acids Research. 25: 1516-22. PMID 9106360 DOI: 10.1093/Nar/25.8.1516 |
0.325 |
|
| 1997 |
Jennewein S, Waring MJ. Footprinting of echinomycin and actinomycin D on DNA molecules asymmetrically substituted with inosine and/or 2,6-diaminopurine. Nucleic Acids Research. 25: 1502-10. PMID 9092655 DOI: 10.1093/Nar/25.8.1502 |
0.353 |
|
| 1997 |
Bailly C, Payet D, Travers AA, Waring MJ. PCR-based development of DNA substrates containing modified bases: an efficient system for investigating the role of the exocyclic groups in chemical and structural recognition by minor groove binding drugs and proteins. Proceedings of the National Academy of Sciences of the United States of America. 93: 13623-8. PMID 8942984 DOI: 10.1073/Pnas.93.24.13623 |
0.421 |
|
| 1997 |
Routier S, Cotelle N, Catteau JP, Bernier JL, Waring MJ, Riou JF, Bailly C. Salen-anthraquinone conjugates. Synthesis, DNA-binding and cleaving properties, effects on topoisomerases and cytotoxicity. Bioorganic & Medicinal Chemistry. 4: 1185-96. PMID 8879539 DOI: 10.1016/0968-0896(96)00082-X |
0.354 |
|
| 1997 |
Donohoe TJ, Moore PR, Waring MJ, Newcombe NJ. The directed dihydroxylation of allylic alcohols Tetrahedron Letters. 38: 5027-5030. DOI: 10.1016/S0040-4039(97)01061-7 |
0.659 |
|
| 1996 |
Bailly C, Minnock A, Waring MJ. A simple ligation assay to detect effects of drugs on the curvature/flexibility of DNA. Febs Letters. 396: 253-6. PMID 8914997 DOI: 10.1016/0014-5793(96)01079-4 |
0.355 |
|
| 1996 |
Pommier Y, Kohlhagen G, Bailly C, Waring M, Mazumder aA, Kohn KW. DNA sequence- and structure-selective alkylation of guanine N2 in the DNA minor groove by ecteinascidin 743, a potent antitumor compound from the Caribbean tunicate Ecteinascidia turbinata. Biochemistry. 35: 13303-13309. PMID 8873596 DOI: 10.1021/Bi960306B |
0.443 |
|
| 1996 |
Bailly C, Braña M, Waring MJ. Sequence-selective intercalation of antitumour bis-naphthalimides into DNA. Evidence for an approach via the major groove. European Journal of Biochemistry. 240: 195-208. PMID 8797854 DOI: 10.1111/J.1432-1033.1996.0195H.X |
0.372 |
|
| 1996 |
Marchand C, Bailly C, Nguyen CH, Bisagni E, Garestier T, Hélène C, Waring MJ. Stabilization of triple helical DNA by a benzopyridoquinoxaline intercalator. Biochemistry. 35: 5022-32. PMID 8664295 DOI: 10.1021/Bi952908L |
0.396 |
|
| 1996 |
Bourdouxhe-Housiaux C, Colson P, Houssier C, Waring MJ, Bailly C. Interaction of a DNA-threading netropsin-amsacrine combilexin with DNA and chromatin. Biochemistry. 35: 4251-64. PMID 8605173 DOI: 10.1021/Bi9528098 |
0.452 |
|
| 1996 |
Bailly C, Hamy F, Waring MJ. Cooperativity in the binding of echinomycin to DNA fragments containing closely spaced CpG sites. Biochemistry. 35: 1150-61. PMID 8573569 DOI: 10.1021/Bi951696P |
0.402 |
|
| 1996 |
Routier S, Bernier J, Waring MJ, Colson P, Houssier C, Bailly C. Synthesis of a Functionalized Salen−Copper Complex and Its Interaction with DNA The Journal of Organic Chemistry. 61: 2326-2331. DOI: 10.1021/Jo951840C |
0.411 |
|
| 1995 |
Plouvier B, Houssin R, Hecquet B, Colson P, Houssier C, Waring MJ, Hénichart JP, Bailly C. Antitumor combilexin. A thiazole-containing analogue of netropsin linked to an acridine chromophore. Bioconjugate Chemistry. 5: 475-81. PMID 7849080 DOI: 10.1021/Bc00029A016 |
0.396 |
|
| 1995 |
Waring MJ, Bailly C. DNA recognition by intercalators and hybrid molecules. Journal of Molecular Recognition : Jmr. 7: 109-22. PMID 7826671 DOI: 10.1002/Jmr.300070208 |
0.348 |
|
| 1995 |
Bailly C, Waring MJ. Transferring the purine 2-amino group from guanines to adenines in DNA changes the sequence-specific binding of antibiotics. Nucleic Acids Research. 23: 885-92. PMID 7731800 DOI: 10.1093/NAR/23.6.885 |
0.319 |
|
| 1995 |
Bailly C, Waring MJ, Travers AA. Effects of base substitutions on the binding of a DNA-bending protein. Journal of Molecular Biology. 253: 1-7. PMID 7473705 DOI: 10.1006/Jmbi.1995.0530 |
0.343 |
|
| 1995 |
Bailly C, Waring MJ. The Purine 2-Amino Group as a Critical Recognition Element for Specific DNA Cleavage by Bleomycin and Calicheamicin Journal of the American Chemical Society. 117: 7311-7316. DOI: 10.1021/Ja00133A003 |
0.371 |
|
| 1995 |
Bailly C, Møllegaard N, Nielsen P, Waring M. The influence of the 2-amino group of guanine on DNA conformation. Uranyl and DNase I probing of inosine/diaminopurine substituted DNA. The Embo Journal. 14: 2121-2131. DOI: 10.1002/J.1460-2075.1995.Tb07204.X |
0.313 |
|
| 1994 |
Flock S, Bailly F, Bailly C, Waring MJ, Hénichart JP, Colson P, Houssier C. Interaction of two peptide-acridine conjugates containing the SPKK peptide motif with DNA and chromatin. Journal of Biomolecular Structure & Dynamics. 11: 881-900. PMID 8204221 DOI: 10.1080/07391102.1994.10508039 |
0.365 |
|
| 1994 |
Bailly C, Gentle D, Hamy F, Purcell M, Waring MJ. Localized chemical reactivity in DNA associated with the sequence-specific bisintercalation of echinomycin. The Biochemical Journal. 165-73. PMID 8198530 DOI: 10.1042/Bj3000165 |
0.315 |
|
| 1994 |
Fossé P, René B, Saucier JM, Hénichart JP, Waring MJ, Colson P, Houssier C, Bailly C. Stimulation of site-specific topoisomerase II-mediated DNA cleavage by an N-methylpyrrolecarboxamide-anilinoacridine conjugate: relation to DNA binding. Biochemistry. 33: 9865-74. PMID 8060993 DOI: 10.1021/Bi00199A007 |
0.419 |
|
| 1994 |
Bailly C, Graves DE, Ridge G, Waring MJ. Use of a photoactive derivative of actinomycin to investigate shuffling between binding sites on DNA Biochemistry. 33: 8736-8745. PMID 8038164 DOI: 10.1021/Bi00195A015 |
0.37 |
|
| 1994 |
Ridge GS, Bailly C, Graves DE, Waring MJ. Daunomycin modifies the sequence-selective recognition of DNA by actinomycin Nucleic Acids Research. 22: 5241-5246. PMID 7816612 DOI: 10.1093/Nar/22.24.5241 |
0.34 |
|
| 1994 |
Waring MJ, Bailly C. The purine 2-amino group as a critical recognition element for binding of small molecules to DNA. Gene. 149: 69-79. PMID 7525412 DOI: 10.1016/0378-1119(94)90414-6 |
0.334 |
|
| 1993 |
Bailly C, Cuthbert AW, Gentle D, Knowles MR, Waring MJ. Sequence-selective binding of amiloride to DNA. Biochemistry. 32: 2514-24. PMID 8448110 DOI: 10.1021/Bi00061A008 |
0.44 |
|
| 1993 |
Bailly C, Waring MJ. Preferential intercalation at AT sequences in DNA by lucanthone, hycanthone, and indazole analogs. A footprinting study. Biochemistry. 32: 5985-93. PMID 8389585 DOI: 10.1021/Bi00074A009 |
0.421 |
|
| 1993 |
Sayers EW, Waring MJ. Footprinting titration studies on the binding of echinomycin to DNA incapable of forming Hoogsteen base pairs. Biochemistry. 32: 9094-107. PMID 8369281 DOI: 10.1021/Bi00086A014 |
0.442 |
|
| 1993 |
Pilch DS, Waring MJ, Sun JS, Rougée M, Nguyen CH, Bisagni E, Garestier T, Hélène C. Characterization of a triple helix-specific ligand. BePI (3-methoxy-7H-8-methyl-11- [(3'-amino)propylamino]-benzo[e]pyrido[4,3-b]indole) intercalates into both double-helical and triple-helical DNA. Journal of Molecular Biology. 232: 926-46. PMID 8355278 DOI: 10.1006/Jmbi.1993.1440 |
0.393 |
|
| 1993 |
Marchand C, Bailly C, McLean MJ, Moroney SE, Waring MJ. The 2-amino group of guanine is absolutely required for specific binding of the anti-cancer antibiotic echinomycin to DNA. Nucleic Acids Research. 20: 5601-6. PMID 1454525 DOI: 10.1093/Nar/20.21.5601 |
0.435 |
|
| 1993 |
Bailly C, Marchand C, Waring MJ. New binding sites for antitumor antibiotics created by relocating the purine 2-amino group in DNA Journal of the American Chemical Society. 115: 3784-3785. DOI: 10.1021/Ja00062A058 |
0.383 |
|
| 1992 |
Bailly C, Denny WA, Mellor LE, Wakelin LP, Waring MJ. Sequence specificity of the binding of 9-aminoacridine- and amsacrine-4-carboxamides to DNA studied by DNase I footprinting. Biochemistry. 31: 3514-24. PMID 1554731 DOI: 10.1021/Bi00128A028 |
0.403 |
|
| 1992 |
Bourdouxhe C, Colson P, Houssier C, Sun JS, Montenay-Garestier T, Hélène C, Rivalle C, Bisagni E, Waring MJ, Hénichart JP, Bailly C. Binding of a distamycin-ellipticine hybrid molecule to DNA and chromatin: Spectroscopic, biochemical, and molecular modeling investigations Biochemistry. 31: 12385-12396. PMID 1463725 DOI: 10.1021/Bi00164A013 |
0.431 |
|
| 1992 |
Bailly C, Colson P, Houssier C, Houssin R, Mrani D, Gosselin G, Imbach JL, Waring MJ, Lown JW, Hénichart JP. Binding properties and DNA sequence-specific recognition of two bithiazole-linked netropsin hybrid molecules. Biochemistry. 31: 8349-62. PMID 1381962 |
0.366 |
|
| 1992 |
Bailly C, Sun JS, Colson P, Houssier C, Hélène C, Waring MJ, Hénichart JP. Design of a sequence-specific DNA-cleaving molecule which conjugates a copper-chelating peptide, a netropsin residue, and an acridine chromophore Bioconjugate Chemistry. 3: 100-103. PMID 1325187 DOI: 10.1021/Bc00014A002 |
0.352 |
|
| 1991 |
Bailly C, OhUigin C, Rivalle C, Bisagni E, Hénichart JP, Waring MJ. Sequence-selective binding of an ellipticine derivative to DNA. Nucleic Acids Research. 18: 6283-91. PMID 2173825 DOI: 10.1093/Nar/18.21.6283 |
0.449 |
|
| 1991 |
Alfredson TV, Maki AH, Waring MJ. Optically detected triplet-state magnetic resonance studies of the DNA complexes of the bisquinoline analogue of echinomycin. Biochemistry. 30: 9665-75. PMID 1911753 DOI: 10.1021/Bi00104A014 |
0.36 |
|
| 1990 |
McLean MJ, Waring MJ. Chemical probes reveal no evidence of Hoogsteen base pairing in complexes formed between echinomycin and DNA in solution. Journal of Molecular Recognition : Jmr. 1: 138-51. PMID 3273225 DOI: 10.1002/Jmr.300010307 |
0.339 |
|
| 1990 |
McLean MJ, Seela F, Waring MJ. Echinomycin-induced hypersensitivity to osmium tetroxide of DNA fragments incapable of forming Hoogsteen base pairs. Proceedings of the National Academy of Sciences of the United States of America. 86: 9687-91. PMID 2602369 DOI: 10.1073/Pnas.86.24.9687 |
0.444 |
|
| 1990 |
Chaires JB, Herrera JE, Waring MJ. Preferential binding of daunomycin to 5'ATCG and 5'ATGC sequences revealed by footprinting titration experiments. Biochemistry. 29: 6145-53. PMID 2207063 DOI: 10.1021/Bi00478A006 |
0.326 |
|
| 1988 |
Fox KR, Davies H, Adams GR, Portugal J, Waring MJ. Sequence-specific binding of luzopeptin to DNA. Nucleic Acids Research. 16: 2489-507. PMID 3362673 DOI: 10.1093/Nar/16.6.2489 |
0.438 |
|
| 1988 |
Portugal J, Fox KR, McLean MJ, Richenberg JL, Waring MJ. Diethyl pyrocarbonate can detect a modified DNA structure induced by the binding of quinoxaline antibiotics. Nucleic Acids Research. 16: 3655-70. PMID 3287335 DOI: 10.1093/Nar/16.9.3655 |
0.423 |
|
| 1987 |
Ford K, Fox KR, Neidle S, Waring MJ. DNA sequence preferences for an intercalating porphyrin compound revealed by footprinting. Nucleic Acids Research. 15: 2221-34. PMID 3562226 DOI: 10.1093/Nar/15.5.2221 |
0.305 |
|
| 1987 |
Portugal J, Waring MJ. Antibiotics which can alter the rotational orientation of nucleosome core DNA. Nucleic Acids Research. 14: 8735-54. PMID 3024118 DOI: 10.1093/Nar/14.22.8735 |
0.307 |
|
| 1987 |
Fox KR, Grigg GW, Waring MJ. Sequence-selective binding of phleomycin to DNA. The Biochemical Journal. 243: 847-51. PMID 2444208 DOI: 10.1042/Bj2430847 |
0.34 |
|
| 1986 |
Olsen RK, Ramasamy K, Bhat KL, Low CM, Waring MJ. Synthesis and DNA-binding studies of [lac2,lac6]TANDEM, an analog of des-N-tetramethyltriostin A (TANDEM) having L-lactic acid substituted for each L-alanine residue. Journal of the American Chemical Society. 108: 6032-6. PMID 22175368 DOI: 10.1021/Ja00279A060 |
0.345 |
|
| 1986 |
Fox KR, Waring MJ, Brown JR, Neidle S. DNA sequence preferences for the anti-cancer drug mitoxanthrone and related anthraquinones revealed by DNase I footprinting. Febs Letters. 202: 289-94. PMID 3720951 DOI: 10.1016/0014-5793(86)80703-7 |
0.312 |
|
| 1986 |
Fox KR, Waring MJ. Nucleotide sequence binding preferences of nogalamycin investigated by DNase I footprinting. Biochemistry. 25: 4349-56. PMID 3019386 DOI: 10.1021/Bi00363A026 |
0.38 |
|
| 1986 |
Low CM, Fox KR, Olsen RK, Waring MJ. DNA sequence recognition by under-methylated analogues of triostin A. Nucleic Acids Research. 14: 2015-33. PMID 3008083 DOI: 10.1093/Nar/14.5.2015 |
0.419 |
|
| 1986 |
Fox KR, Waring MJ. Footprinting reveals that nogalamycin and actinomycin shuffle between DNA binding sites. Nucleic Acids Research. 14: 2001-14. PMID 2421246 DOI: 10.1093/Nar/14.5.2001 |
0.409 |
|
| 1985 |
Fox KR, Waring MJ. Evidence of different binding sites for nogalamycin in DNA revealed by association kinetics. Biochimica Et Biophysica Acta. 802: 162-8. PMID 6498212 DOI: 10.1016/0304-4165(84)90157-0 |
0.33 |
|
| 1985 |
Fox KR, Waring MJ. Kinetic evidence for redistribution of actinomycin molecules between potential DNA-binding sites. European Journal of Biochemistry. 145: 579-86. PMID 6210201 DOI: 10.1111/J.1432-1033.1984.Tb08596.X |
0.307 |
|
| 1985 |
Fox KR, Brassett C, Waring MJ. Kinetics of dissociation of nogalamycin from DNA: comparison with other anthracycline antibiotics. Biochimica Et Biophysica Acta. 840: 383-92. PMID 3859336 DOI: 10.1016/0304-4165(85)90219-3 |
0.306 |
|
| 1984 |
Fox KR, Waring MJ. Stopped-flow kinetic studies on the interaction between echinomycin and DNA. Biochemistry. 23: 2627-33. PMID 6466601 DOI: 10.1021/Bi00307A014 |
0.427 |
|
| 1984 |
Sheldrick GM, Guy JJ, Kennard O, Rivera V, Waring MJ. Crystal and molecular structure of the DNA-binding antitumour antibiotic triostin A Journal of the Chemical Society-Perkin Transactions 1. 16: 1601-1605. DOI: 10.1039/P29840001601 |
0.37 |
|
| 1983 |
Baez A, González FA, Vázquez D, Waring MJ. Interaction between a 3-nitrobenzothiazolo (3,2-a) quinolinium antitumour drug and deoxyribonucleic acid. Biochemical Pharmacology. 32: 2089-94. PMID 6870936 DOI: 10.1016/0006-2952(83)90431-8 |
0.32 |
|
| 1983 |
Cornish A, Fox KR, Waring MJ. Preparation and DNA-binding properties of substituted triostin antibiotics Antimicrobial Agents and Chemotherapy. 23: 221-231. PMID 6838186 DOI: 10.1128/AAC.23.2.221 |
0.315 |
|
| 1982 |
Wakelin LP, Adams A, Hunter C, Waring MJ. Interaction of crystal violet with nucleic acids. Biochemistry. 20: 5779-87. PMID 6170329 DOI: 10.1021/Bi00523A021 |
0.306 |
|
| 1981 |
Fox KR, Waring MJ. Kinetics of dissociation of quinoxaline antibiotics from DNA. Biochimica Et Biophysica Acta. 654: 279-86. PMID 7284382 DOI: 10.1016/0005-2787(81)90182-9 |
0.348 |
|
| 1981 |
Fox KR, Gauvreau D, Goodwin DC, Waring MJ. Binding of quinoline analogues of echinomycin to deoxyribonucleic acid. Role of the chromophores. The Biochemical Journal. 191: 729-42. PMID 7283970 DOI: 10.1042/Bj1910729 |
0.308 |
|
| 1981 |
Wright RG, Wakelin LP, Fieldes A, Acheson RM, Waring MJ. Effects of ring substituents and linker chains on the bifunctional intercalation of diacridines into deoxyribonucleic acid. Biochemistry. 19: 5825-36. PMID 7193050 DOI: 10.1021/BI00566A026 |
0.31 |
|
| 1979 |
Waring MJ, González A, Jiménez A, Vázquez D. Intercalative binding to DNA of antitumour drugs derived from 3-nitro-1,8-naphthalic acid. Nucleic Acids Research. 7: 217-30. PMID 573892 DOI: 10.1093/Nar/7.1.217 |
0.326 |
|
| 1978 |
Lee JS, Waring MJ. Interaction between synthetic analogues of quinoxaline antibiotics and nucleic acids. Changes in mechanism and specificity related to structural alterations. The Biochemical Journal. 173: 129-44. PMID 687364 DOI: 10.1042/BJ1730129 |
0.338 |
|
| 1976 |
Waring MJ, Wakelin LP, Lee JS. A solvent-partition method for measuring the binding of drugs to DNA. Application to the quinoxaline antibiotics echinomycin and triostin A. Biochimica Et Biophysica Acta. 407: 200-12. PMID 1237323 DOI: 10.1016/0005-2787(75)90285-3 |
0.33 |
|
| 1975 |
Waring MJ, Wakelin LP. Echinomycin: a bifunctional intercalating antibiotic. Nature. 252: 653-7. PMID 4437614 DOI: 10.1038/252653A0 |
0.315 |
|
| 1970 |
Waring MJ. Drugs and DNA: uncoiling of the DNA double helix as evidence of intercalation. Humangenetik. 9: 234-6. PMID 5451687 DOI: 10.1007/BF00279229 |
0.311 |
|
| 1966 |
Waring MJ. Complex formation between ethidium bromide and nucleic acids. Journal of Molecular Biology. 13: 269-82. PMID 5859041 DOI: 10.1016/S0022-2836(65)80096-1 |
0.301 |
|
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