| Year |
Citation |
Score |
| 2024 |
Na B, Haist B, Shah SR, Sabiston G, Jonas SJ, Vitte J, Wirz RE, Giovannini M. Cold Atmospheric Plasma Induces Growth Arrest and Apoptosis in Neurofibromatosis Type 1-Associated Peripheral Nerve Sheath Tumor Cells. Biomedicines. 12. PMID 39335500 DOI: 10.3390/biomedicines12091986 |
0.775 |
|
| 2024 |
Nghiemphu PL, Vitte J, Dombi E, Nguyen T, Wagle N, Ishiyama A, Sepahdari AR, Cachia D, Widemann BC, Brackmann DE, Doherty JK, Kalamarides M, Giovannini M. Imaging as an early biomarker to predict sensitivity to everolimus for progressive NF2-related vestibular schwannoma. Journal of Neuro-Oncology. PMID 38372904 DOI: 10.1007/s11060-024-04596-4 |
0.726 |
|
| 2023 |
Staedtke V, Anstett K, Bedwell D, Giovannini M, Keeling K, Kesterson R, Kim Y, Korf B, Leier A, McManus ML, Sarnoff H, Vitte J, Walker JA, Plotkin SR, Wallis D. Gene-targeted therapy for neurofibromatosis and schwannomatosis: The path to clinical trials. Clinical Trials (London, England). 17407745231207970. PMID 37937606 DOI: 10.1177/17407745231207970 |
0.734 |
|
| 2023 |
Jordan JT, Orr CC, Thalheimer RD, Cambillo JV, Beauchamp RL, Shaikh G, Muzikansky A, Stemmer-Rachamimov A, Giovannini M, Kalamarides M, Barker FG, Ramesh V, Plotkin SR. Prospective phase II trial of the dual mTORC1/2 inhibitor vistusertib for progressive or symptomatic meningiomas in persons with neurofibromatosis 2. Neuro-Oncology Advances. 5: vdad041. PMID 37215956 DOI: 10.1093/noajnl/vdad041 |
0.312 |
|
| 2023 |
Chiasson-MacKenzie C, Vitte J, Liu CH, Wright EA, Flynn EA, Stott SL, Giovannini M, McClatchey AI. Cellular mechanisms of heterogeneity in NF2-mutant schwannoma. Nature Communications. 14: 1559. PMID 36944680 DOI: 10.1038/s41467-023-37226-0 |
0.784 |
|
| 2022 |
Prabhakar S, Beauchamp RL, Cheah PS, Yoshinaga A, Haidar EA, Lule S, Mani G, Maalouf K, Stemmer-Rachamimov A, Jung DH, Welling DB, Giovannini M, Plotkin SR, Maguire CA, Ramesh V, et al. Gene replacement therapy in a schwannoma mouse model of neurofibromatosis type 2. Molecular Therapy. Methods & Clinical Development. 26: 169-180. PMID 35846573 DOI: 10.1016/j.omtm.2022.06.012 |
0.435 |
|
| 2022 |
Plotkin SR, Messiaen L, Legius E, Pancza P, Avery RA, Blakeley JO, Babovic-Vuksanovic D, Ferner R, Fisher MJ, Friedman JM, Giovannini M, Gutmann DH, Hanemann CO, Kalamarides M, Kehrer-Sawatzki H, et al. Updated diagnostic criteria and nomenclature for neurofibromatosis type 2 and schwannomatosis: An international consensus recommendation. Genetics in Medicine : Official Journal of the American College of Medical Genetics. PMID 35674741 DOI: 10.1016/j.gim.2022.05.007 |
0.318 |
|
| 2020 |
Ma J, Klemm J, Gerardo-Ramírez M, Frappart L, Castven D, Becker D, Zoch A, Parent R, Bartosch B, Minnich K, Giovannini M, Danckwardt S, Hartmann N, Morrison H, Herrlich P, et al. CD44 (Cluster of differentiation 44) promotes osteosarcoma progression in mice lacking the tumor suppressor Merlin. International Journal of Cancer. PMID 32525563 DOI: 10.1002/Ijc.33144 |
0.34 |
|
| 2019 |
Ahmed SG, Ahmed A, Maguire CA, Doha M, Sagers J, Lewis RM, Muzikansky A, Giovannini M, Stemmer-Rachamimov A, Stankovic KM, Fulci G, Brenner GJ. Gene therapy with apoptosis-associated speck-like protein (ASC), a newly described schwannoma tumor suppressor, inhibits schwannoma growth in vivo. Neuro-Oncology. PMID 30977509 DOI: 10.1093/Neuonc/Noz065 |
0.407 |
|
| 2019 |
Ferner RE, Bakker A, Elgersma Y, Evans DGR, Giovannini M, Legius E, Lloyd A, Messiaen LM, Plotkin S, Reilly KM, Schindeler A, Smith MJ, Ullrich NJ, Widemann B, Sherman LS. From process to progress-2017 International Conference on Neurofibromatosis 1, Neurofibromatosis 2 and Schwannomatosis. American Journal of Medical Genetics. Part A. PMID 30908866 DOI: 10.1002/Ajmg.A.61112 |
0.471 |
|
| 2019 |
Roberts DS, Maurya R, Takemon Y, Vitte J, Gong L, Zhao J, Wong CH, Slattery W, Peng KA, Lekovic G, Schwartz MS, Bulsara K, Ngan CY, Giovannini M, Wei CL. Linked-read Sequencing Analysis Reveals Tumor-specific Genome Variation Landscapes in Neurofibromatosis Type 2 (NF2) Patients. Otology & Neurotology : Official Publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology. 40: e150-e159. PMID 30624408 DOI: 10.1097/Mao.0000000000002096 |
0.786 |
|
| 2019 |
Fuse MA, Dinh CT, Vitte J, Kirkpatrick J, Mindos T, Plati SK, Young JI, Huang J, Carlstedt A, Franco MC, Brnjos K, Nagamoto J, Petrilli A, Copik AJ, Soulakova JN, ... ... Giovannini M, et al. Preclinical Assessment of MEK1/2 Inhibitors for Neurofibromatosis Type 2-Associated Schwannomas Reveal Differences in Efficacy and Drug Resistance Development. Neuro-Oncology. PMID 30615146 DOI: 10.1093/Neuonc/Noz002 |
0.784 |
|
| 2019 |
Osum S, Stemmer-Rachamimov A, Widemann B, Dombi E, Vitte J, Dahiya S, Rizvi T, Ratner N, Messiaen L, Gutmann D, Giovannini M, Moertel C, Largaespada D, Watson A. TMOD-23. PRECLINICAL DRUG EVALUATION IN A GENETICALLY ENGINEERED MINIPIG MODEL OF NEUROFIBROMATOSIS TYPE 1 Neuro-Oncology. 21: vi267-vi267. DOI: 10.1093/Neuonc/Noz175.1122 |
0.775 |
|
| 2019 |
Vitte J, Gao F, Coppola G, Judkins AR, Giovannini M. TMOD-15. SPATIOTEMPORAL LOSS OF SMARCB1 IN EARLY NEURAL CREST LINEAGE LEADS TO DIFFERENT MOLECULAR SUBTYPES OF RHABDOID TUMORS Neuro-Oncology. 21: ii124-ii124. DOI: 10.1093/Neuonc/Noz036.252 |
0.752 |
|
| 2018 |
Isakson SH, Rizzardi AE, Coutts AW, Carlson DF, Kirstein MN, Fisher J, Vitte J, Williams KB, Pluhar GE, Dahiya S, Widemann BC, Dombi E, Rizvi T, Ratner N, Messiaen L, ... ... Giovannini M, et al. Genetically engineered minipigs model the major clinical features of human neurofibromatosis type 1. Communications Biology. 1: 158. PMID 30302402 DOI: 10.1038/s42003-018-0163-y |
0.746 |
|
| 2018 |
Fisher MJ, Belzberg AJ, de Blank P, De Raedt T, Elefteriou F, Ferner RE, Giovannini M, Harris GJ, Kalamarides M, Karajannis MA, Kim A, Lázaro C, Le LQ, Li W, Listernick R, et al. 2016 Children's Tumor Foundation conference on neurofibromatosis type 1, neurofibromatosis type 2, and schwannomatosis. American Journal of Medical Genetics. Part A. 176: 1258-1269. PMID 29681099 DOI: 10.1002/Ajmg.A.38675 |
0.501 |
|
| 2018 |
Nghiemphu P, Everson R, Giovannini M, Reider-Demer M, Wainberg Z, Ishiyama A. CMET-04. METASTATIC GASTROINTESTINAL CANCER TO THE SKULL BASE MIMICKING NF2 Neuro-Oncology. 20: vi54-vi54. DOI: 10.1093/Neuonc/Noy148.217 |
0.373 |
|
| 2017 |
Paganini I, Capone GL, Vitte J, Sestini R, Putignano AL, Giovannini M, Papi L. Double somatic SMARCB1 and NF2 mutations in sporadic spinal schwannoma. Journal of Neuro-Oncology. PMID 29230670 DOI: 10.1007/S11060-017-2711-6 |
0.766 |
|
| 2017 |
Vitte J, Gao F, Coppola G, Judkins AR, Giovannini M. Timing of Smarcb1 and Nf2 inactivation determines schwannoma versus rhabdoid tumor development. Nature Communications. 8: 300. PMID 28824165 DOI: 10.1038/S41467-017-00346-5 |
0.798 |
|
| 2017 |
Paldor I, Abbadi S, Bonne N, Ye X, Rodriguez FJ, Rowshanshad D, Itzoe M, Vigilar V, Giovannini M, Brem H, Blakeley JO, Tyler BM. The efficacy of lapatinib and nilotinib in combination with radiation therapy in a model of NF2 associated peripheral schwannoma. Journal of Neuro-Oncology. PMID 28735458 DOI: 10.1007/S11060-017-2567-9 |
0.436 |
|
| 2017 |
Blakeley JO, Bakker A, Barker A, Clapp W, Ferner R, Fisher MJ, Giovannini M, Gutmann DH, Karajannis MA, Kissil JL, Legius E, Lloyd AC, Packer RJ, Ramesh V, Riccardi VM, et al. The path forward: 2015 International Children's Tumor Foundation conference on neurofibromatosis type 1, type 2, and schwannomatosis. American Journal of Medical Genetics. Part A. PMID 28436162 DOI: 10.1002/Ajmg.A.38239 |
0.481 |
|
| 2017 |
Goutagny S, Giovannini M, Kalamarides M. A 4-year phase II study of everolimus in NF2 patients with growing vestibular schwannomas. Journal of Neuro-Oncology. 133: 443-445. PMID 28434114 DOI: 10.1007/S11060-017-2447-3 |
0.302 |
|
| 2016 |
Shi Y, Bollam SR, White SM, Laughlin SZ, Graham GT, Wadhwa M, Chen H, Nguyen C, Vitte J, Giovannini M, Toretsky J, Yi C. Rac1-Mediated DNA Damage and Inflammation Promote Nf2 Tumorigenesis but Also Limit Cell-Cycle Progression. Developmental Cell. PMID 27818180 DOI: 10.1016/J.Devcel.2016.09.027 |
0.791 |
|
| 2016 |
Bonne NX, Vitte J, Chareyre F, Karapetyan G, Khankaldyyan V, Tanaka K, Moats RA, Giovannini M. An allograft mouse model for the study of hearing loss secondary to vestibular schwannoma growth. Journal of Neuro-Oncology. PMID 27177628 DOI: 10.1007/S11060-016-2150-9 |
0.75 |
|
| 2015 |
Peyre M, Salaud C, Clermont-Taranchon E, Niwa-Kawakita M, Goutagny S, Mawrin C, Giovannini M, Kalamarides M. PDGF activation in PGDS-positive arachnoid cells induces meningioma formation in mice promoting tumor progression in combination with Nf2 and Cdkn2ab loss. Oncotarget. 6: 32713-22. PMID 26418719 DOI: 10.18632/Oncotarget.5296 |
0.4 |
|
| 2015 |
Zoch A, Mayerl S, Schulz A, Greither T, Frappart L, Rübsam J, Heuer H, Giovannini M, Morrison H. Merlin Isoforms 1 and 2 Both Act as Tumour Suppressors and Are Required for Optimal Sperm Maturation. Plos One. 10: e0129151. PMID 26258444 DOI: 10.1371/Journal.Pone.0129151 |
0.404 |
|
| 2015 |
Goutagny S, Raymond E, Esposito-Farese M, Trunet S, Mawrin C, Bernardeschi D, Larroque B, Sterkers O, Giovannini M, Kalamarides M. Phase II study of mTORC1 inhibition by everolimus in neurofibromatosis type 2 patients with growing vestibular schwannomas. Journal of Neuro-Oncology. 122: 313-20. PMID 25567352 DOI: 10.1007/S11060-014-1710-0 |
0.397 |
|
| 2015 |
Serinagaoglu Y, Paré J, Giovannini M, Cao X. Nf2-Yap signaling controls the expansion of DRG progenitors and glia during DRG development. Developmental Biology. 398: 97-109. PMID 25433207 DOI: 10.1016/J.Ydbio.2014.11.017 |
0.411 |
|
| 2015 |
Paganini I, Chang VY, Capone GL, Vitte J, Benelli M, Barbetti L, Sestini R, Trevisson E, Hulsebos TJ, Giovannini M, Nelson SF, Papi L. Expanding the mutational spectrum of LZTR1 in schwannomatosis. European Journal of Human Genetics : Ejhg. 23: 963-8. PMID 25335493 DOI: 10.1038/Ejhg.2014.220 |
0.784 |
|
| 2015 |
Vitte J, Chareyre F, Stemmer-Rachamimov A, Judkins A, Giovannini M. PM-02 * CONDITIONAL INACTIVATION OF SMARCB1 IN P0 PERMISSIVE MOUSE CELLS GENERATES RHABDOID TUMORS IN THE PERIPHERAL NERVOUS SYSTEM AND IN THE BRAIN Neuro-Oncology. 17: iii31-iii31. DOI: 10.1093/Neuonc/Nov061.125 |
0.783 |
|
| 2014 |
Plotkin SR, Albers AC, Babovic-Vuksanovic D, Blakeley JO, Breakefield XO, Dunn CM, Evans DG, Fisher MJ, Friedman JM, Giovannini M, Gutmann DH, Kalamarides M, McClatchey AI, Messiaen L, Morrison H, et al. Update from the 2013 International Neurofibromatosis Conference. American Journal of Medical Genetics. Part A. 164: 2969-78. PMID 25255738 DOI: 10.1002/Ajmg.A.36754 |
0.493 |
|
| 2014 |
Widemann BC, Acosta MT, Ammoun S, Belzberg AJ, Bernards A, Blakeley J, Bretscher A, Cichowski K, Clapp DW, Dombi E, Evans GD, Ferner R, Fernandez-Valle C, Fisher MJ, Giovannini M, et al. CTF meeting 2012: Translation of the basic understanding of the biology and genetics of NF1, NF2, and schwannomatosis toward the development of effective therapies. American Journal of Medical Genetics. Part A. 164: 563-78. PMID 24443315 DOI: 10.1002/Ajmg.A.36312 |
0.506 |
|
| 2014 |
Giovannini M, Bonne NX, Vitte J, Chareyre F, Tanaka K, Adams R, Fisher LM, Valeyrie-Allanore L, Wolkenstein P, Goutagny S, Kalamarides M. mTORC1 inhibition delays growth of neurofibromatosis type 2 schwannoma. Neuro-Oncology. 16: 493-504. PMID 24414536 DOI: 10.1093/Neuonc/Not242 |
0.788 |
|
| 2014 |
Petrilli A, Copik A, Posadas M, Chang LS, Welling DB, Giovannini M, Fernández-Valle C. LIM domain kinases as potential therapeutic targets for neurofibromatosis type 2. Oncogene. 33: 3571-82. PMID 23934191 DOI: 10.1038/onc.2013.320 |
0.368 |
|
| 2014 |
Vitte J, Chareyre F, Stemmer-Rachamimov A, Judkins A, Giovannini M. Conditional Inactivation of SMARCB1 in P0 Permissive Mouse Cells Generates Rhabdoid Tumors in the Peripheral Nervous System Cancer Genetics. 207: 451. DOI: 10.1016/J.Cancergen.2014.09.023 |
0.758 |
|
| 2013 |
Lavado A, He Y, Paré J, Neale G, Olson EN, Giovannini M, Cao X. Tumor suppressor Nf2 limits expansion of the neural progenitor pool by inhibiting Yap/Taz transcriptional coactivators. Development (Cambridge, England). 140: 3323-34. PMID 23863479 DOI: 10.1242/Dev.096537 |
0.449 |
|
| 2013 |
Tanaka K, Eskin A, Chareyre F, Jessen WJ, Manent J, Niwa-Kawakita M, Chen R, White CH, Vitte J, Jaffer ZM, Nelson SF, Rubenstein AE, Giovannini M. Therapeutic potential of HSP90 inhibition for neurofibromatosis type 2. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 19: 3856-70. PMID 23714726 DOI: 10.1158/1078-0432.Ccr-12-3167 |
0.734 |
|
| 2013 |
Schulz A, Baader SL, Niwa-Kawakita M, Jung MJ, Bauer R, Garcia C, Zoch A, Schacke S, Hagel C, Mautner VF, Hanemann CO, Dun XP, Parkinson DB, Weis J, Schröder JM, ... ... Giovannini M, et al. Merlin isoform 2 in neurofibromatosis type 2-associated polyneuropathy. Nature Neuroscience. 16: 426-33. PMID 23455610 DOI: 10.1038/Nn.3348 |
0.462 |
|
| 2013 |
Plotkin SR, Blakeley JO, Evans DG, Hanemann CO, Hulsebos TJ, Hunter-Schaedle K, Kalpana GV, Korf B, Messiaen L, Papi L, Ratner N, Sherman LS, Smith MJ, Stemmer-Rachamimov AO, Vitte J, ... Giovannini M, et al. Update from the 2011 International Schwannomatosis Workshop: From genetics to diagnostic criteria. American Journal of Medical Genetics. Part A. 161: 405-16. PMID 23401320 DOI: 10.1002/Ajmg.A.35760 |
0.78 |
|
| 2013 |
Jessen WJ, Miller SJ, Jousma E, Wu J, Rizvi TA, Brundage ME, Eaves D, Widemann B, Kim MO, Dombi E, Sabo J, Hardiman Dudley A, Niwa-Kawakita M, Page GP, Giovannini M, et al. MEK inhibition exhibits efficacy in human and mouse neurofibromatosis tumors. The Journal of Clinical Investigation. 123: 340-7. PMID 23221341 DOI: 10.1172/Jci60578 |
0.481 |
|
| 2013 |
Peyre M, Stemmer-Rachamimov A, Clermont-Taranchon E, Quentin S, El-Taraya N, Walczak C, Volk A, Niwa-Kawakita M, Karboul N, Giovannini M, Kalamarides M. Meningioma progression in mice triggered by Nf2 and Cdkn2ab inactivation Oncogene. 32: 4264-4272. PMID 23045274 DOI: 10.1038/Onc.2012.436 |
0.484 |
|
| 2013 |
Lavado A, He Y, Pare J, Neale G, Olson EN, Giovannini M, Cao X. Tumor suppressor Nf2 limits expansion of the neural progenitor pool by inhibiting Yap/Taz transcriptional coactivators Journal of Cell Science. 126: e1-e1. DOI: 10.1242/jcs.138818 |
0.35 |
|
| 2012 |
Pei Y, Brun SN, Markant SL, Lento W, Gibson P, Taketo MM, Giovannini M, Gilbertson RJ, Wechsler-Reya RJ. WNT signaling increases proliferation and impairs differentiation of stem cells in the developing cerebellum. Development (Cambridge, England). 139: 1724-33. PMID 22461560 DOI: 10.1242/Dev.050104 |
0.327 |
|
| 2012 |
Blakeley JO, Evans DG, Adler J, Brackmann D, Chen R, Ferner RE, Hanemann CO, Harris G, Huson SM, Jacob A, Kalamarides M, Karajannis MA, Korf BR, Mautner VF, McClatchey AI, ... ... Giovannini M, et al. Consensus recommendations for current treatments and accelerating clinical trials for patients with neurofibromatosis type 2. American Journal of Medical Genetics. Part A. 158: 24-41. PMID 22140088 DOI: 10.1002/Ajmg.A.34359 |
0.473 |
|
| 2011 |
Yogesha SD, Sharff AJ, Giovannini M, Bricogne G, Izard T. Unfurling of the band 4.1, ezrin, radixin, moesin (FERM) domain of the merlin tumor suppressor. Protein Science : a Publication of the Protein Society. 20: 2113-20. PMID 22012890 DOI: 10.1002/Pro.751 |
0.447 |
|
| 2011 |
Cooper J, Li W, You L, Schiavon G, Pepe-Caprio A, Zhou L, Ishii R, Giovannini M, Hanemann CO, Long SB, Erdjument-Bromage H, Zhou P, Tempst P, Giancotti FG. Merlin/NF2 functions upstream of the nuclear E3 ubiquitin ligase CRL4DCAF1 to suppress oncogenic gene expression. Science Signaling. 4: pt6. PMID 21878678 DOI: 10.1126/Scisignal.2002314 |
0.5 |
|
| 2011 |
Jean D, Thomas E, Manié E, Renier A, de Reynies A, Lecomte C, Andujar P, Fleury-Feith J, Galateau-Sallé F, Giovannini M, Zucman-Rossi J, Stern MH, Jaurand MC. Syntenic relationships between genomic profiles of fiber-induced murine and human malignant mesothelioma. The American Journal of Pathology. 178: 881-94. PMID 21281820 DOI: 10.1016/J.Ajpath.2010.10.039 |
0.337 |
|
| 2011 |
Huson SM, Acosta MT, Belzberg AJ, Bernards A, Chernoff J, Cichowski K, Gareth Evans D, Ferner RE, Giovannini M, Korf BR, Listernick R, North KN, Packer RJ, Parada LF, Peltonen J, et al. Back to the future: proceedings from the 2010 NF Conference. American Journal of Medical Genetics. Part A. 155: 307-21. PMID 21271647 DOI: 10.1002/Ajmg.A.33804 |
0.469 |
|
| 2011 |
Kalamarides M, Stemmer-Rachamimov AO, Niwa-Kawakita M, Chareyre F, Taranchon E, Han ZY, Martinelli C, Lusis EA, Hegedus B, Gutmann DH, Giovannini M. Identification of a progenitor cell of origin capable of generating diverse meningioma histological subtypes. Oncogene. 30: 2333-44. PMID 21242963 DOI: 10.1038/Onc.2010.609 |
0.366 |
|
| 2011 |
Peyre M, Stemmer-Rachamimov A, Taranchon E, Niwa-Kawakita M, Quentin S, Giovannini M, Kalamarides M. Coopération de NF2 et CDKN2AB dans un modèle murin transgénique de méningiome de grade 2/3 Neurochirurgie. 57: 267. DOI: 10.1016/J.Neuchi.2011.09.055 |
0.324 |
|
| 2010 |
Kalamarides M, Peyre M, Giovannini M. Meningioma mouse models. Journal of Neuro-Oncology. 99: 325-31. PMID 20734219 DOI: 10.1007/S11060-010-0331-5 |
0.461 |
|
| 2010 |
Goutagny S, Yang HW, Zucman-Rossi J, Chan J, Dreyfuss JM, Park PJ, Black PM, Giovannini M, Carroll RS, Kalamarides M. Genomic profiling reveals alternative genetic pathways of meningioma malignant progression dependent on the underlying NF2 status. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 16: 4155-64. PMID 20682713 DOI: 10.1158/1078-0432.Ccr-10-0891 |
0.406 |
|
| 2010 |
Benhamouche S, Curto M, Saotome I, Gladden AB, Liu CH, Giovannini M, McClatchey AI. Nf2/Merlin controls progenitor homeostasis and tumorigenesis in the liver. Genes & Development. 24: 1718-30. PMID 20675406 DOI: 10.1101/Gad.1938710 |
0.367 |
|
| 2010 |
Zhang N, Bai H, David KK, Dong J, Zheng Y, Cai J, Giovannini M, Liu P, Anders RA, Pan D. The Merlin/NF2 tumor suppressor functions through the YAP oncoprotein to regulate tissue homeostasis in mammals. Developmental Cell. 19: 27-38. PMID 20643348 DOI: 10.1016/J.Devcel.2010.06.015 |
0.442 |
|
| 2010 |
Wiley LA, Dattilo LK, Kang KB, Giovannini M, Beebe DC. The tumor suppressor merlin is required for cell cycle exit, terminal differentiation, and cell polarity in the developing murine lens. Investigative Ophthalmology & Visual Science. 51: 3611-8. PMID 20181838 DOI: 10.1167/Iovs.09-4371 |
0.494 |
|
| 2010 |
Li W, You L, Cooper J, Schiavon G, Pepe-Caprio A, Zhou L, Ishii R, Giovannini M, Hanemann CO, Long SB, Erdjument-Bromage H, Zhou P, Tempst P, Giancotti FG. Merlin/NF2 suppresses tumorigenesis by inhibiting the E3 ubiquitin ligase CRL4(DCAF1) in the nucleus. Cell. 140: 477-90. PMID 20178741 DOI: 10.1016/J.Cell.2010.01.029 |
0.478 |
|
| 2009 |
Miller SJ, Jessen WJ, Mehta T, Hardiman A, Sites E, Kaiser S, Jegga AG, Li H, Upadhyaya M, Giovannini M, Muir D, Wallace MR, Lopez E, Serra E, Nielsen GP, et al. Integrative genomic analyses of neurofibromatosis tumours identify SOX9 as a biomarker and survival gene. Embo Molecular Medicine. 1: 236-48. PMID 20049725 DOI: 10.1002/Emmm.200900027 |
0.424 |
|
| 2009 |
Lallemand D, Saint-Amaux AL, Giovannini M. Tumor-suppression functions of merlin are independent of its role as an organizer of the actin cytoskeleton in Schwann cells. Journal of Cell Science. 122: 4141-9. PMID 19910496 DOI: 10.1242/Jcs.045914 |
0.386 |
|
| 2009 |
Evans DG, Kalamarides M, Hunter-Schaedle K, Blakeley J, Allen J, Babovic-Vuskanovic D, Belzberg A, Bollag G, Chen R, DiTomaso E, Golfinos J, Harris G, Jacob A, Kalpana G, Karajannis M, ... ... Giovannini M, et al. Consensus recommendations to accelerate clinical trials for neurofibromatosis type 2. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 15: 5032-9. PMID 19671848 DOI: 10.1158/1078-0432.Ccr-08-3011 |
0.472 |
|
| 2009 |
Lee TX, Packer MD, Huang J, Akhmametyeva EM, Kulp SK, Chen CS, Giovannini M, Jacob A, Welling DB, Chang LS. Growth inhibitory and anti-tumour activities of OSU-03012, a novel PDK-1 inhibitor, on vestibular schwannoma and malignant schwannoma cells. European Journal of Cancer (Oxford, England : 1990). 45: 1709-20. PMID 19359162 DOI: 10.1016/J.Ejca.2009.03.013 |
0.318 |
|
| 2009 |
Mercher T, Raffel GD, Moore SA, Cornejo MG, Baudry-Bluteau D, Cagnard N, Jesneck JL, Pikman Y, Cullen D, Williams IR, Akashi K, Shigematsu H, Bourquin JP, Giovannini M, Vainchenker W, et al. The OTT-MAL fusion oncogene activates RBPJ-mediated transcription and induces acute megakaryoblastic leukemia in a knockin mouse model. The Journal of Clinical Investigation. 119: 852-64. PMID 19287095 DOI: 10.1172/Jci35901 |
0.353 |
|
| 2009 |
Boulday G, Blécon A, Petit N, Chareyre F, Garcia LA, Niwa-Kawakita M, Giovannini M, Tournier-Lasserve E. Tissue-specific conditional CCM2 knockout mice establish the essential role of endothelial CCM2 in angiogenesis: implications for human cerebral cavernous malformations. Disease Models & Mechanisms. 2: 168-77. PMID 19259391 DOI: 10.1242/Dmm.001263 |
0.3 |
|
| 2009 |
Coulpier F, Le Crom S, Maro GS, Manent J, Giovannini M, Maciorowski Z, Fischer A, Gessler M, Charnay P, Topilko P. Novel features of boundary cap cells revealed by the analysis of newly identified molecular markers. Glia. 57: 1450-7. PMID 19243017 DOI: 10.1002/Glia.20862 |
0.332 |
|
| 2009 |
Houshmandi SS, Emnett RJ, Giovannini M, Gutmann DH. The neurofibromatosis 2 protein, merlin, regulates glial cell growth in an ErbB2- and Src-dependent manner. Molecular and Cellular Biology. 29: 1472-86. PMID 19103750 DOI: 10.1128/Mcb.01392-08 |
0.377 |
|
| 2009 |
Lallemand D, Manent J, Couvelard A, Watilliaux A, Siena M, Chareyre F, Lampin A, Niwa-Kawakita M, Kalamarides M, Giovannini M. Merlin regulates transmembrane receptor accumulation and signaling at the plasma membrane in primary mouse Schwann cells and in human schwannomas. Oncogene. 28: 854-865. PMID 19029950 DOI: 10.1038/Onc.2008.427 |
0.375 |
|
| 2008 |
Denisenko N, Cifuentes-Diaz C, Irinopoulou T, Carnaud M, Benoit E, Niwa-Kawakita M, Chareyre F, Giovannini M, Girault JA, Goutebroze L. Tumor suppressor schwannomin/merlin is critical for the organization of Schwann cell contacts in peripheral nerves. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 10472-81. PMID 18923024 DOI: 10.1523/Jneurosci.2537-08.2008 |
0.42 |
|
| 2008 |
Haigis KM, Kendall KR, Wang Y, Cheung A, Haigis MC, Glickman JN, Niwa-Kawakita M, Sweet-Cordero A, Sebolt-Leopold J, Shannon KM, Settleman J, Giovannini M, Jacks T. Differential effects of oncogenic K-Ras and N-Ras on proliferation, differentiation and tumor progression in the colon. Nature Genetics. 40: 600-8. PMID 18372904 DOI: 10.1038/Ng.115 |
0.335 |
|
| 2008 |
Ramos OHP, Kauskot A, Cominetti MR, Bechyne I, Pontes CLS, Chareyre F, Manent J, Vassy R, Giovannini M, Legrand C, Selistre-de-Araujo HS, Crépin M, Bonnefoy A. A novel αvβ3-blocking disintegrin containing the RGD motive, DisBa-01, inhibits bFGF-induced angiogenesis and melanoma metastasis Clinical & Experimental Metastasis. 25: 53-64. PMID 17952617 DOI: 10.1007/S10585-007-9101-Y |
0.325 |
|
| 2008 |
Kalamarides M, Stemmer-Rachamimov AO, Takahashi M, Han ZY, Chareyre F, Niwa-Kawakita M, Black PM, Carroll RS, Giovannini M. Natural history of meningioma development in mice reveals: a synergy of Nf2 and p16(Ink4a) mutations. Brain Pathology (Zurich, Switzerland). 18: 62-70. PMID 17924978 DOI: 10.1111/J.1750-3639.2007.00105.X |
0.503 |
|
| 2008 |
Mercher T, Raffel GD, Moore SA, Cornejo MG, Baudry-Bluteau D, Cagnard N, Jesneck J, Pikman Y, Cullen DE, Williams I, Akashi K, Shigematsu H, Bourquin J, Giovannini M, Vainchenker W, et al. OTT-MAL Activates the Notch Signaling Transcription Factor RBPJ and Cooperates with Mutant MPL to Induce Acute Megakaryoblastic Leukemia Blood. 112: 508-508. DOI: 10.1182/Blood.V112.11.508.508 |
0.387 |
|
| 2007 |
Muranen T, Grönholm M, Lampin A, Lallemand D, Zhao F, Giovannini M, Carpén O. The tumor suppressor merlin interacts with microtubules and modulates Schwann cell microtubule cytoskeleton Human Molecular Genetics. 16: 1742-1751. PMID 17566081 DOI: 10.1093/Hmg/Ddm122 |
0.392 |
|
| 2006 |
Messerli SM, Prabhakar S, Tang Y, Mahmood U, Giovannini M, Weissleder R, Bronson R, Martuza R, Rabkin S, Breakefield XO. Treatment of schwannomas with an oncolytic recombinant herpes simplex virus in murine models of neurofibromatosis type 2. Human Gene Therapy. 17: 20-30. PMID 16409122 DOI: 10.1089/Hum.2006.17.20 |
0.437 |
|
| 2005 |
Lecomte C, Andujar P, Renier A, Kheuang L, Abramowski V, Mellottee L, Fleury-Feith J, Zucman-Rossi J, Giovannini M, Jaurand MC. Similar tumor suppressor gene alteration profiles in asbestos-induced murine and human mesothelioma. Cell Cycle (Georgetown, Tex.). 4: 1862-9. PMID 16319530 DOI: 10.4161/Cc.4.12.2300 |
0.45 |
|
| 2005 |
McClatchey AI, Giovannini M. Membrane organization and tumorigenesis--the NF2 tumor suppressor, Merlin. Genes & Development. 19: 2265-77. PMID 16204178 DOI: 10.1101/Gad.1335605 |
0.463 |
|
| 2004 |
Robanus-Maandag E, Giovannini M, Van Der Valk M, Niwa-Kawakita M, Abramowski V, Antonescu C, Thomas G, Berns A. Synergy of Nf2 and p53 mutations in development of malignant tumours of neural crest origin Oncogene. 23: 6541-6547. PMID 15221010 DOI: 10.1038/Sj.Onc.1207858 |
0.711 |
|
| 2004 |
Stemmer-Rachamimov AO, Louis DN, Nielsen GP, Antonescu CR, Borowsky AD, Bronson RT, Burns DK, Cervera P, McLaughlin ME, Reifenberger G, Schmale MC, MacCollin M, Chao RC, Cichowski K, Kalamarides M, ... ... Giovannini M, et al. Comparative pathology of nerve sheath tumors in mouse models and humans. Cancer Research. 64: 3718-24. PMID 15150133 DOI: 10.1158/0008-5472.Can-03-4079 |
0.465 |
|
| 2004 |
Hirokawa Y, Tikoo A, Huynh J, Utermark T, Hanemann CO, Giovannini M, Xiao GH, Testa JR, Wood J, Maruta H. A clue to the therapy of neurofibromatosis type 2: NF2/Merlin is a PAK inhibitor Cancer Journal. 10: 20-25. PMID 15000491 DOI: 10.1097/00130404-200401000-00006 |
0.467 |
|
| 2003 |
Fleury-Feith J, Lecomte C, Renier A, Matrat M, Kheuang L, Abramowski V, Levy F, Janin A, Giovannini M, Jaurand M. Hemizygosity of Nf2 is associated with increased susceptibility to asbestos-induced peritoneal tumours. Oncogene. 22: 3799-3805. PMID 12802287 DOI: 10.1038/Sj.Onc.1206593 |
0.453 |
|
| 2003 |
Gutmann DH, Baker SJ, Giovannini M, Garbow J, Weiss W. Mouse models of human cancer consortium symposium on nervous system tumors. Cancer Research. 63: 3001-4. PMID 12782610 |
0.34 |
|
| 2003 |
Lallemand D, Curto M, Saotome I, Giovannini M, McClatchey AI. NF2 deficiency promotes tumorigenesis and metastasis by destabilizing adherens junctions. Genes & Development. 17: 1090-100. PMID 12695331 DOI: 10.1101/Gad.1054603 |
0.473 |
|
| 2003 |
Utermark T, Alekov A, Lerche H, Abramowski V, Giovannini M, Hanemann CO. Quinidine impairs proliferation of neurofibromatosis type 2-deficient human malignant mesothelioma cells. Cancer. 97: 1955-62. PMID 12673723 DOI: 10.1002/Cncr.11275 |
0.482 |
|
| 2003 |
Chamaillard M, Philpott D, Girardin SE, Zouali H, Lesage S, Chareyre F, Bui TH, Giovannini M, Zaehringer U, Penard-Lacronique V, Sansonetti PJ, Hugot JP, Thomas G. Gene-environment interaction modulated by allelic heterogeneity in inflammatory diseases. Proceedings of the National Academy of Sciences of the United States of America. 100: 3455-60. PMID 12626759 DOI: 10.1073/Pnas.0530276100 |
0.539 |
|
| 2003 |
Manent J, Oguievetskaia K, Bayer J, Ratner N, Giovannini M. Magnetic cell sorting for enriching Schwann cells from adult mouse peripheral nerves. Journal of Neuroscience Methods. 123: 167-73. PMID 12606065 DOI: 10.1016/S0165-0270(02)00349-7 |
0.325 |
|
| 2003 |
Leneuve P, Colnot S, Hamard G, Francis F, Niwa-Kawakita M, Giovannini M, Holzenberger M. Cre-mediated germline mosaicism: a new transgenic mouse for the selective removal of residual markers from tri-lox conditional alleles. Nucleic Acids Research. 31: e21. PMID 12595570 DOI: 10.1093/Nar/Gng021 |
0.302 |
|
| 2002 |
Sun CX, Haipek C, Scoles DR, Pulst SM, Giovannini M, Komada M, Gutmann DH. Functional analysis of the relationship between the neurofibromatosis 2 tumor suppressor and its binding partner, hepatocyte growth factor-regulated tyrosine kinase substrate. Human Molecular Genetics. 11: 3167-78. PMID 12444101 DOI: 10.1093/Hmg/11.25.3167 |
0.378 |
|
| 2002 |
Messerli SM, Tang Y, Giovannini M, Bronson R, Weissleder R, Breakefield XO. Detection of spontaneous schwannomas by MRI in a transgenic murine model of neurofibromatosis type 2. Neoplasia (New York, N.Y.). 4: 501-9. PMID 12407444 DOI: 10.1038/Sj.Neo.7900265 |
0.452 |
|
| 2002 |
Weiss WA, Israel M, Cobbs C, Holland E, James CD, Louis DN, Marks C, McClatchey AI, Roberts T, Van Dyke T, Wetmore C, Chiu IM, Giovannini M, Guha A, Higgins RJ, et al. Neuropathology of genetically engineered mice: consensus report and recommendations from an international forum. Oncogene. 21: 7453-63. PMID 12386807 DOI: 10.1038/Sj.Onc.1205936 |
0.453 |
|
| 2002 |
Gautreau A, Manent J, Fievet B, Louvard D, Giovannini M, Arpin M. Mutant products of the NF2 tumor suppressor gene are degraded by the ubiquitin-proteasome pathway. The Journal of Biological Chemistry. 277: 31279-82. PMID 12130630 DOI: 10.1074/Jbc.C200125200 |
0.385 |
|
| 2002 |
Gutmann DH, Giovannini M. Mouse models of neurofibromatosis 1 and 2 Neoplasia. 4: 279-290. PMID 12082543 DOI: 10.1038/Sj.Neo.7900249 |
0.535 |
|
| 2002 |
Kalamarides M, Niwa-Kawakita M, Leblois H, Abramowski V, Perricaudet M, Janin A, Thomas G, Gutmann DH, Giovannini M. Nf2 gene inactivation in arachnoidal cells is rate-limiting for meningioma development in the mouse. Genes & Development. 16: 1060-5. PMID 12000789 DOI: 10.1101/Gad.226302 |
0.675 |
|
| 2000 |
Lim DJ, Rubenstein AE, Evans DG, Jacks T, Seizinger BG, Baser ME, Beebe D, Brackmann DE, Chiocca EA, Fehon RG, Giovannini M, Glazer R, Gusella JF, Gutmann DH, Korf B, et al. Advances in neurofibromatosis 2 (NF2): a workshop report. Journal of Neurogenetics. 14: 63-106. PMID 10992163 DOI: 10.3109/01677060009083477 |
0.367 |
|
| 2000 |
Niwa-Kawakita M, Abramowski V, Kalamarides M, Thomas G, Giovannini M. Targeted expression of Cre recombinase to myelinating cells of the central nervous system in transgenic mice Genesis. 26: 127-129. PMID 10686606 DOI: 10.1002/(Sici)1526-968X(200002)26:2<127::Aid-Gene8>3.0.Co;2-H |
0.515 |
|
| 2000 |
Carron C, Cormier F, Janin A, Lacronique V, Giovannini M, Daniel M, Bernard O, Ghysdael J. TEL-JAK2 transgenic mice develop T-cell leukemia. Blood. 95: 3891-3899. DOI: 10.1182/Blood.V95.12.3891.012K13_3891_3899 |
0.317 |
|
| 2000 |
Giovannini M, Robanus-Maandag E, Valk Mvd, Niwa-Kawakita M, Abramowski V, Goutebroze L, Woodruff JM, Berns A, Thomas G. Conditional biallelic Nf2 mutation in the mouse promotes manifestations of human neurofibromatosis type 2 Genes & Development. 14: 1617-1630. DOI: 10.1101/Gad.14.13.1617 |
0.663 |
|
| 1999 |
Giovannini M, Robanus-Maandag E, Niwa-Kawakita M, van der Valk M, Woodruff JM, Goutebroze L, Mérel P, Berns A, Thomas G. Schwann cell hyperplasia and tumors in transgenic mice expressing a naturally occurring mutant NF2 protein. Genes & Development. 13: 978-86. PMID 10215625 DOI: 10.1101/Gad.13.8.978 |
0.646 |
|
| 1998 |
Deguen B, Goutebroze L, Giovannini M, Boisson C, Neut Rvd, Jaurand M, Thomas G. Heterogeneity of mesothelioma cell lines as defined by altered genomic structure and expression of the NF2 gene. International Journal of Cancer. 77: 554-560. PMID 9679758 DOI: 10.1002/(Sici)1097-0215(19980812)77:4<554::Aid-Ijc14>3.0.Co;2-6 |
0.643 |
|
| 1997 |
Akagi K, Sandig V, Vooijs M, Valk MVd, Giovannini M, Strauss M, Berns A. Cre-mediated somatic site-specific recombination in mice Nucleic Acids Research. 25: 1766-1773. PMID 9108159 DOI: 10.1093/Nar/25.9.1766 |
0.3 |
|
| 1996 |
Thomas G, Merel P, Giovannini M, Niwa-Kawakita M, Robanus-Maandag E, Berns A, Goutebrose L, Deguen B. The NF2 tumor suppressor gene Cancer Genetics and Cytogenetics. 91: 110. DOI: 10.1016/S0165-4608(97)82511-3 |
0.656 |
|
| 1994 |
Ruttledge MH, Xie Y, Han F, Giovannini M, Janson M, Fransson I, Werelius B, Delattre O, Thomas G, Evans G, Dumanski JP. Physical mapping of the NF2/meningioma region on human chromosome 22q12. Genomics. 19: 52-59. PMID 8188242 DOI: 10.1006/Geno.1994.1012 |
0.691 |
|
| 1994 |
Giovannini M, Biegel JA, Serra M, Wang JY, Wei YH, Nycum L, Emanuel BS, Evans GA. EWS-erg and EWS-Fli1 fusion transcripts in Ewing's sarcoma and primitive neuroectodermal tumors with variant translocations Journal of Clinical Investigation. 94: 489-496. PMID 8040301 DOI: 10.1172/Jci117360 |
0.671 |
|
| 1994 |
Selleri L, Giovannini M, Romo A, Zucman J, Delattre O, Thomas G, Evans GA. Cloning of the entire FLI1 gene, disrupted by the Ewing's sarcoma translocation breakpoint on 11q24, in a yeast artificial chromosome. Cytogenetic and Genome Research. 67: 129-136. PMID 8039423 DOI: 10.1159/000133813 |
0.605 |
|
| 1994 |
Selleri L, Giovannini M, Hermanson GG, Romo A, Quackenbush J, Penny L, Khristich JV, Evans GA. Yeast Artificial Chromosome Cloning of 3.2 Megabases within Chromosomal Band 11q24 Closely Linking c-ets 1 and Fli-1 and Encompassing the Ewing Sarcoma Breakpoint Genomics. 22: 137-147. PMID 7959760 DOI: 10.1006/Geno.1994.1354 |
0.607 |
|
| 1993 |
Giovannini M, Romo AJ, Evans GA. Chromosomal localization of the human ciliary neurotrophic factor gene (CNTF) to 11 q12 by fluorescence in situ hybridization Cytogenetic and Genome Research. 63: 62-63. PMID 8449041 DOI: 10.1159/000133504 |
0.608 |
|
| 1993 |
Giovannini M, Selleri L, Hermanson GG, Evans GA. Localization of the human oncostatin M gene (OSM) to chromosome 22q12, distal to the Ewing's sarcoma breakpoint. Cytogenetics and Cell Genetics. 62: 32-4. PMID 8422753 DOI: 10.1159/000133439 |
0.609 |
|
| 1993 |
Giovannini M, Djabali M, McElligott D, Selleri L, Evans GA. Tandem linkage of genes coding for leukemia inhibitory factor (LIF) and oncostatin M (OSM) on human chromosome 22 Cytogenetic and Genome Research. 64: 240-244. PMID 8404048 DOI: 10.1159/000133586 |
0.604 |
|
| 1993 |
Giovannini M, Selleri L, Evans GA. Fluorescent in situ hybridization for the detection of the t(11;22)(q24;q12) in small round cell tumors Cancer Genetics and Cytogenetics. 66: 167. DOI: 10.1016/0165-4608(93)90352-M |
0.622 |
|
| 1992 |
Giovannini M, Selleri L, Biegel JA, Scotlandi K, Emanuel BS, Evans GA. Interphase cytogenetics for the detection of the t(11;22)(q24;q12) in small round cell tumors Journal of Clinical Investigation. 90: 1911-1918. PMID 1430213 DOI: 10.1172/Jci116068 |
0.668 |
|
| 1992 |
Selleri L, Eubanks JH, Giovannini M, Hermanson GG, Romo A, Djabali M, Maurer S, McElligott DL, Smith MW, Evans GA. Detection and characterization of "chimeric" yeast artificial chromosome clones by fluorescent in situ suppression hybridization. Genomics. 14: 536-41. PMID 1427876 DOI: 10.1016/S0888-7543(05)80263-0 |
0.578 |
|
| 1992 |
Selleri L, Giovannini M, Hermanson GG, Romo A, Serra M, Djabali M, Evans GA. Molecular characterization of the (11;22)(q24;q12) translocation of Ewing's sarcoma: Isolation of new diagnostic probes on 11q24–q25 for FISSH Cancer Genetics and Cytogenetics. 63: 162. DOI: 10.1016/0165-4608(92)90502-Y |
0.579 |
|
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