| Year |
Citation |
Score |
| 2017 |
Berns KI, Muzyczka N. AAV: AN OVERVIEW OF UNANSWERED QUESTIONS. Human Gene Therapy. PMID 28335618 DOI: 10.1089/Hum.2017.048 |
0.657 |
|
| 2016 |
Aydemir F, Salganik M, Resztak J, Singh J, Bennett A, Agbandje-McKenna M, Muzyczka N. Mutants at the 2-fold interface of AAV2 structural proteins suggest a role in viral transcription for AAV capsids. Journal of Virology. PMID 27252527 DOI: 10.1128/Jvi.00493-16 |
0.333 |
|
| 2016 |
Zhang D, Li J, Feng Y, Snowden A, Aslanidi G, Muzyczka N, Srivastava A, Ling C, Ling C. 95. Incorporation of AAV Serotype 2 Viral Protein 2 into Other AAV Serotype Capsids Molecular Therapy. 24: S41-S42. DOI: 10.1016/S1525-0016(16)32904-5 |
0.371 |
|
| 2015 |
Berns KI, Byrne BJ, Flotte TR, Gao G, Hauswirth WW, Herzog RW, Muzyczka N, VandenDriessche T, Xiao X, Zolotukhin S, Srivastava A. Adeno-Associated Virus Type 2 and Hepatocellular Carcinoma? Human Gene Therapy. 26: 779-81. PMID 26690810 DOI: 10.1089/Hum.2015.29014.Kib |
0.684 |
|
| 2015 |
Muzyczka N, Berns KI. AAV's Golden Jubilee. Molecular Therapy : the Journal of the American Society of Gene Therapy. 23: 807-8. PMID 25943495 DOI: 10.1038/Mt.2015.55 |
0.643 |
|
| 2015 |
Ling C, Wang Y, Lu Y, Wang L, Jayandharan GR, Aslanidi GV, Li B, Cheng B, Ma W, Lentz T, Ling C, Xiao X, Samulski RJ, Muzyczka N, Srivastava A. Enhanced transgene expression from recombinant single-stranded D-sequence-substituted adeno-associated virus vectors in human cell lines in vitro and in murine hepatocytes in vivo. Journal of Virology. 89: 952-61. PMID 25355884 DOI: 10.1128/Jvi.02581-14 |
0.529 |
|
| 2014 |
Salganik M, Aydemir F, Nam HJ, McKenna R, Agbandje-McKenna M, Muzyczka N. Adeno-associated virus capsid proteins may play a role in transcription and second-strand synthesis of recombinant genomes. Journal of Virology. 88: 1071-9. PMID 24198419 DOI: 10.1128/Jvi.02093-13 |
0.344 |
|
| 2013 |
Govindasamy L, DiMattia MA, Gurda BL, Halder S, McKenna R, Chiorini JA, Muzyczka N, Zolotukhin S, Agbandje-McKenna M. Structural insights into adeno-associated virus serotype 5. Journal of Virology. 87: 11187-99. PMID 23926356 DOI: 10.1128/Jvi.00867-13 |
0.306 |
|
| 2010 |
Choi YK, Nash K, Byrne BJ, Muzyczka N, Song S. The effect of DNA-dependent protein kinase on adeno-associated virus replication. Plos One. 5: e15073. PMID 21188139 DOI: 10.1371/Journal.Pone.0015073 |
0.355 |
|
| 2008 |
Nash K, Chen W, Muzyczka N. Complete in vitro reconstitution of adeno-associated virus DNA replication requires the minichromosome maintenance complex proteins. Journal of Virology. 82: 1458-64. PMID 18057257 DOI: 10.1128/Jvi.01968-07 |
0.402 |
|
| 2008 |
Snyder R, Potter M, Phillipsberg G, Phillipsberg T, Petersen M, Sanders D, Fife J, Korytov I, Zolotukhin S, Muzyczka N, Francis J, Flotte T. Manufacture and Stability of the Recombinant Adeno-Associated Virus Serotype 2 Vector Reference Standard Bioprocessing Journal. 7: 8-14. DOI: 10.12665/J72.Snyder |
0.326 |
|
| 2007 |
Nam HJ, Lane MD, Padron E, Gurda B, McKenna R, Kohlbrenner E, Aslanidi G, Byrne B, Muzyczka N, Zolotukhin S, Agbandje-McKenna M. Structure of adeno-associated virus serotype 8, a gene therapy vector. Journal of Virology. 81: 12260-71. PMID 17728238 DOI: 10.1128/Jvi.01304-07 |
0.331 |
|
| 2007 |
Nash K, Chen W, McDonald WF, Zhou X, Muzyczka N. Purification of host cell enzymes involved in adeno-associated virus DNA replication. Journal of Virology. 81: 5777-87. PMID 17360744 DOI: 10.1128/Jvi.02651-06 |
0.373 |
|
| 2006 |
Brantly ML, Spencer LT, Humphries M, Conlon TJ, Spencer CT, Poirier A, Garlington W, Baker D, Song S, Berns KI, Muzyczka N, Snyder RO, Byrne BJ, Flotte TR. Phase I trial of intramuscular injection of a recombinant adeno-associated virus serotype 2 alphal-antitrypsin (AAT) vector in AAT-deficient adults. Human Gene Therapy. 17: 1177-86. PMID 17115945 DOI: 10.1089/Hum.2006.17.1177 |
0.683 |
|
| 2006 |
Govindasamy L, Padron E, McKenna R, Muzyczka N, Kaludov N, Chiorini JA, Agbandje-McKenna M. Structurally mapping the diverse phenotype of adeno-associated virus serotype 4. Journal of Virology. 80: 11556-70. PMID 16971437 DOI: 10.1128/Jvi.01536-06 |
0.328 |
|
| 2005 |
Gigout L, Rebollo P, Clement N, Warrington KH, Muzyczka N, Linden RM, Weber T. Altering AAV tropism with mosaic viral capsids. Molecular Therapy : the Journal of the American Society of Gene Therapy. 11: 856-65. PMID 15922956 DOI: 10.1016/J.Ymthe.2005.03.005 |
0.318 |
|
| 2005 |
Muzyczka N, Warrington KH. Custom adeno-associated virus capsids: the next generation of recombinant vectors with novel tropism. Human Gene Therapy. 16: 408-16. PMID 15871672 DOI: 10.1089/Hum.2005.16.408 |
0.329 |
|
| 2005 |
Padron E, Bowman V, Kaludov N, Govindasamy L, Levy H, Nick P, McKenna R, Muzyczka N, Chiorini JA, Baker TS, Agbandje-McKenna M. Structure of adeno-associated virus type 4. Journal of Virology. 79: 5047-58. PMID 15795290 DOI: 10.1128/Jvi.79.8.5047-5058.2005 |
0.327 |
|
| 2004 |
Lou HJ, Brister JR, Li JJ, Chen W, Muzyczka N, Tan W. Adeno-associated virus Rep78/Rep68 promotes localized melting of the rep binding element in the absence of adenosine triphosphate. Chembiochem : a European Journal of Chemical Biology. 5: 324-32. PMID 14997524 DOI: 10.1002/Cbic.200300737 |
0.682 |
|
| 2003 |
Li Z, Brister JR, Im DS, Muzyczka N. Characterization of the adenoassociated virus Rep protein complex formed on the viral origin of DNA replication. Virology. 313: 364-76. PMID 12954205 DOI: 10.1016/S0042-6822(03)00340-4 |
0.698 |
|
| 2003 |
Opie SR, Warrington KH, Agbandje-McKenna M, Zolotukhin S, Muzyczka N. Identification of amino acid residues in the capsid proteins of adeno-associated virus type 2 that contribute to heparan sulfate proteoglycan binding. Journal of Virology. 77: 6995-7006. PMID 12768018 DOI: 10.1128/Jvi.77.12.6995-7006.2003 |
0.304 |
|
| 2002 |
Zolotukhin S, Potter M, Zolotukhin I, Sakai Y, Loiler S, Fraites TJ, Chiodo VA, Phillipsberg T, Muzyczka N, Hauswirth WW, Flotte TR, Byrne BJ, Snyder RO. Production and purification of serotype 1, 2, and 5 recombinant adeno-associated viral vectors. Methods (San Diego, Calif.). 28: 158-67. PMID 12413414 DOI: 10.1016/S1046-2023(02)00220-7 |
0.338 |
|
| 2000 |
Klein RL, Mandel RJ, Muzyczka N. Adeno-associated virus vector-mediated gene transfer to somatic cells in the central nervous system. Advances in Virus Research. 55: 507-28. PMID 11050954 DOI: 10.1016/S0065-3527(00)55015-5 |
0.326 |
|
| 2000 |
Wu P, Xiao W, Conlon T, Hughes J, Agbandje-McKenna M, Ferkol T, Flotte T, Muzyczka N. Mutational analysis of the adeno-associated virus type 2 (AAV2) capsid gene and construction of AAV2 vectors with altered tropism. Journal of Virology. 74: 8635-47. PMID 10954565 DOI: 10.1128/Jvi.74.18.8635-8647.2000 |
0.524 |
|
| 2000 |
Brister JR, Muzyczka N. Mechanism of Rep-mediated adeno-associated virus origin nicking. Journal of Virology. 74: 7762-71. PMID 10933682 DOI: 10.1128/Jvi.74.17.7762-7771.2000 |
0.724 |
|
| 2000 |
Hauswirth WW, Lewin AS, Zolotukhin S, Muzyczka N. Production and purification of recombinant adeno-associated virus. Methods in Enzymology. 316: 743-61. PMID 10800712 DOI: 10.1016/S0076-6879(00)16760-6 |
0.333 |
|
| 2000 |
Gavin DK, Young SM, Xiao W, Temple B, Abernathy CR, Pereira DJ, Muzyczka N, Samulski RJ. Charge-to-Alanine Mutagenesis of the Adeno-Associated Virus Type 2 Rep78/68 Proteins Yields Temperature-Sensitive and Magnesium-Dependent Variants Journal of Virology. 74: 591-591. DOI: 10.1128/Jvi.74.1.591-591.2000 |
0.53 |
|
| 1999 |
Gavin DK, Young SM, Xiao W, Temple B, Abernathy CR, Pereira DJ, Muzyczka N, Samulski RJ. Charge-to-alanine mutagenesis of the adeno-associated virus type 2 Rep78/68 proteins yields temperature-sensitive and magnesium-dependent variants. Journal of Virology. 73: 9433-45. PMID 10516052 |
0.372 |
|
| 1999 |
Brister JR, Muzyczka N. Rep-mediated nicking of the adeno-associated virus origin requires two biochemical activities, DNA helicase activity and transesterification. Journal of Virology. 73: 9325-36. PMID 10516041 DOI: 10.1128/Jvi.73.11.9325-9336.1999 |
0.705 |
|
| 1999 |
Conway JE, Rhys CM, Zolotukhin I, Zolotukhin S, Muzyczka N, Hayward GS, Byrne BJ. High-titer recombinant adeno-associated virus production utilizing a recombinant herpes simplex virus type I vector expressing AAV-2 Rep and Cap. Gene Therapy. 6: 986-93. PMID 10455400 DOI: 10.1038/Sj.Gt.3300937 |
0.357 |
|
| 1999 |
Zhou X, Zolotukhin I, Im DS, Muzyczka N. Biochemical characterization of adeno-associated virus rep68 DNA helicase and ATPase activities. Journal of Virology. 73: 1580-90. PMID 9882364 DOI: 10.1128/Jvi.73.2.1580-1590.1999 |
0.324 |
|
| 1998 |
Zhou X, Muzyczka N. In vitro packaging of adeno-associated virus DNA. Journal of Virology. 72: 3241-7. PMID 9525651 |
0.319 |
|
| 1998 |
Ni TH, McDonald WF, Zolotukhin I, Melendy T, Waga S, Stillman B, Muzyczka N. Cellular proteins required for adeno-associated virus DNA replication in the absence of adenovirus coinfection. Journal of Virology. 72: 2777-87. PMID 9525597 DOI: 10.1128/Jvi.72.4.2777-2787.1998 |
0.377 |
|
| 1997 |
Conway JE, Zolotukhin S, Muzyczka N, Hayward GS, Byrne BJ. Recombinant adeno-associated virus type 2 replication and packaging is entirely supported by a herpes simplex virus type 1 amplicon expressing Rep and Cap. Journal of Virology. 71: 8780-9. PMID 9343238 DOI: 10.1128/Jvi.71.11.8780-8789.1997 |
0.412 |
|
| 1996 |
Gnalenko D, Arnold T, Zolotukhin S, Muzyczka N, Bahou W. Recombinant adeno-associated virus-2 (raav) as a vector for gene delivery into vascular cells Journal of Investigative Medicine. 44: 319a. |
0.319 |
|
| 1995 |
Einerhand MP, Antoniou M, Zolotukhin S, Muzyczka N, Berns KI, Grosveld F, Valerio D. Regulated high-level human beta-globin gene expression in erythroid cells following recombinant adeno-associated virus-mediated gene transfer. Gene Therapy. 2: 336-43. PMID 7671109 |
0.669 |
|
| 1994 |
Ni TH, Zhou X, Mccarty DM, Zolotukhin I, Muzyczka N. In vitro replication of adeno-associated virus DNA Journal of Virology. 68: 1128-1138. PMID 8289342 |
0.402 |
|
| 1994 |
Mccarty DM, Ryan JH, Zolotukhin S, Zhou X, Muzyczka N. Interaction of the adeno-associated virus Rep protein with a sequence within the A palindrome of the viral terminal repeat Journal of Virology. 68: 4998-5006. PMID 8035499 |
0.323 |
|
| 1994 |
Muzyczka N. Adeno-associated virus (AAV) vectors: Will they work? Journal of Clinical Investigation. 94: 1351. PMID 7929808 |
0.318 |
|
| 1993 |
Snyder RO, Im DS, Ni T, Xiao X, Samulski RJ, Muzyczka N. Features of the adeno-associated virus origin involved in substrate recognition by the viral rep protein Journal of Virology. 67: 6096-6104. PMID 8396670 DOI: 10.1128/Jvi.67.10.6096-6104.1993 |
0.478 |
|
| 1993 |
Snyder RO, Im DS, Ni T, Xiao X, Samulski RJ, Muzyczka N. Features of the adeno-associated virus origin involved in substrate recognition by the viral Rep protein. Journal of Virology. 67: 6096-6104. DOI: 10.1128/jvi.67.10.6096-6104.1993 |
0.302 |
|
| 1992 |
Mccarty DM, Ni TH, Muzyczka N. Analysis of mutations in adeno-associated virus rep protein in vivo and in vitro Journal of Virology. 66: 4050-4057. PMID 1318396 |
0.336 |
|
| 1992 |
Muzyczka N. Use of adeno-associated virus as a general transduction vector for mammalian cells Current Topics in Microbiology and Immunology. 158: 97-129. PMID 1316261 |
0.327 |
|
| 1992 |
Im DS, Muzyczka N. Partial purification of adeno-associated virus Rep78, Rep52, and Rep40 and their biochemical characterization Journal of Virology. 66: 1119-1128. PMID 1309894 |
0.306 |
|
| 1990 |
Snyder RO, Im DS, Muzyczka N. Evidence for covalent attachment of the adeno-associated virus (AAV) Rep protein to the ends of the AAV genome Journal of Virology. 64: 6204-6213. PMID 2173787 |
0.403 |
|
| 1990 |
Im DS, Muzyczka N. The AAV origin binding protein Rep68 is an ATP-dependent site-specific endonuclease with DNA helicase activity Cell. 61: 447-457. PMID 2159383 DOI: 10.1016/0092-8674(90)90526-K |
0.383 |
|
| 1990 |
Kotin RM, Siniscalco M, Samulski RJ, Zhu XD, Hunter L, Laughlin CA, McLaughlin S, Muzyczka N, Rocchi M, Berns KI. Site-specific integration by adeno-associated virus. Proceedings of the National Academy of Sciences of the United States of America. 87: 2211-5. PMID 2156265 DOI: 10.1073/Pnas.87.6.2211 |
0.698 |
|
| 1990 |
Snyder RO, Samulski RJ, Muzyczka N. In vitro resolution of covalently joined AAV chromosome ends Cell. 60: 105-113. PMID 2153052 DOI: 10.1016/0092-8674(90)90720-Y |
0.397 |
|
| 1989 |
Im DS, Muzyczka N. Factors that bind to adeno-associated virus terminal repeats Journal of Virology. 63: 3095-3104. PMID 2542617 |
0.33 |
|
| 1988 |
Gottlieb J, Muzyczka N. In vitro excision of adeno-associated virus DNA from recombinant plasmids: isolation of an enzyme fraction from HeLa cells that cleaves DNA at poly(G) sequences. Molecular and Cellular Biology. 8: 2513-22. PMID 2841582 |
0.371 |
|
| 1988 |
McLaughlin SK, Collis P, Hermonat PL, Muzyczka N. Adeno-associated virus general transduction vectors: Analysis of proviral structures Journal of Virology. 62: 1963-1973. PMID 2835501 |
0.466 |
|
| 1985 |
Rayfield M, Michaels GS, Feldmann R, Muzyczka N. Comparison of the DNA sequence and secondary structure of the herpes simplex virus L/S junction and the adeno-associated virus terminal repeat Journal of Theoretical Biology. 115: 477-494. PMID 2995732 DOI: 10.1016/S0022-5193(85)80136-3 |
0.386 |
|
| 1984 |
Muzyczka N, Samulski RJ, Hermonat P, Srivastava A, Berns KI. The genetics of adeno-associated virus. Advances in Experimental Medicine and Biology. 179: 151-61. PMID 6098150 DOI: 10.1007/978-1-4684-8730-5_15 |
0.744 |
|
| 1984 |
Hermonat PL, Muzyczka N. Use of adeno-associated virus as a mammalian DNA cloning vector: Transduction of neomycin resistance into mammalian tissue culture cells Proceedings of the National Academy of Sciences of the United States of America. 81: 6466-6470. PMID 6093102 DOI: 10.1073/Pnas.81.20.6466 |
0.429 |
|
| 1984 |
Hermonat PL, Labow MA, Wright R, Berns KI, Muzyczka N. Genetics of adeno-associated virus: isolation and preliminary characterization of adeno-associated virus type 2 mutants. Journal of Virology. 51: 329-39. PMID 6086948 DOI: 10.1128/Jvi.51.2.329-339.1984 |
0.717 |
|
| 1983 |
Samulski RJ, Srivastava A, Berns KI, Muzyczka N. Rescue of adeno-associated virus from recombinant plasmids: gene correction within the terminal repeats of AAV. Cell. 33: 135-43. PMID 6088052 DOI: 10.1016/0092-8674(83)90342-2 |
0.712 |
|
| 1982 |
Samulski RJ, Berns KI, Tan M, Muzyczka N. Cloning of adeno-associated virus into pBR322: rescue of intact virus from the recombinant plasmid in human cells. Proceedings of the National Academy of Sciences of the United States of America. 79: 2077-81. PMID 6281795 DOI: 10.1073/Pnas.79.6.2077 |
0.746 |
|
| 1980 |
Muzyczka N. Construction of an SV40-derived cloning vector Gene. 11: 63-77. PMID 6254855 |
0.391 |
|
| 1980 |
Rawlins DR, Muzyczka N. Construction of a specific amber codon in the simian virus 40 T-antigen gene by site-directed mutagenesis Journal of Virology. 36: 611-616. PMID 6253682 |
0.371 |
|
| 1979 |
Muzyczka N. Persistence of phage λ DNA in genomes of mouse cells transformed by λ-carrying SV40 vectors Gene. 6: 107-122. PMID 225241 DOI: 10.1016/0378-1119(79)90066-0 |
0.332 |
|
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