| Year |
Citation |
Score |
| 2023 |
Grätz L, Kowalski-Jahn M, Scharf MM, Kozielewicz P, Jahn M, Bous J, Lambert NA, Gloriam DE, Schulte G. Pathway selectivity in Frizzleds is achieved by conserved micro-switches defining pathway-determining, active conformations. Nature Communications. 14: 4573. PMID 37516754 DOI: 10.1038/s41467-023-40213-0 |
0.354 |
|
| 2023 |
Grätz L, Sajkowska-Kozielewicz JJ, Wesslowski J, Kinsolving J, Bridge LJ, Petzold K, Davidson G, Schulte G, Kozielewicz P. NanoBiT- and NanoBiT/BRET-based assays allow the analysis of binding kinetics of Wnt-3a to endogenous Frizzled 7 in a colorectal cancer model. British Journal of Pharmacology. PMID 37055379 DOI: 10.1111/bph.16090 |
0.329 |
|
| 2023 |
Bowin CF, Kozielewicz P, Grätz L, Kowalski-Jahn M, Schihada H, Schulte G. WNT stimulation induces dynamic conformational changes in the Frizzled-Dishevelled interaction. Science Signaling. 16: eabo4974. PMID 37014927 DOI: 10.1126/scisignal.abo4974 |
0.369 |
|
| 2022 |
Schihada H, Klompstra TM, Humphrys LJ, Cervenka I, Dadvar S, Kolb P, Ruas JL, Schulte G. Isoforms of GPR35 have distinct extracellular N-termini that allosterically modify receptor-transducer coupling and mediate intracellular pathway bias. The Journal of Biological Chemistry. 102328. PMID 35933013 DOI: 10.1016/j.jbc.2022.102328 |
0.328 |
|
| 2021 |
Kozielewicz P, Schihada H, Schulte G. Employing Genetically Encoded, Biophysical Sensors to Understand WNT/Frizzled Interaction and Receptor Complex Activation. Handbook of Experimental Pharmacology. PMID 34463848 DOI: 10.1007/164_2021_534 |
0.32 |
|
| 2021 |
Kozielewicz P, Shekhani R, Moser S, Bowin CF, Wesslowski J, Davidson G, Schulte G. Quantitative Profiling of WNT-3A Binding to All Human Frizzled Paralogues in HEK293 Cells by NanoBiT/BRET Assessments. Acs Pharmacology & Translational Science. 4: 1235-1245. PMID 34151213 DOI: 10.1021/acsptsci.1c00084 |
0.363 |
|
| 2020 |
Schihada H, Kowalski-Jahn M, Turku A, Schulte G. Deconvolution of WNT-induced Frizzled conformational dynamics with fluorescent biosensors. Biosensors & Bioelectronics. 177: 112948. PMID 33486136 DOI: 10.1016/j.bios.2020.112948 |
0.353 |
|
| 2020 |
Schihada H, Ma X, Zabel U, Vischer HF, Schulte G, Leurs R, Pockes S, Lohse MJ. Development of a conformational histamine H receptor biosensor for the synchronous screening of agonists and inverse agonists. Acs Sensors. PMID 32397705 DOI: 10.1021/Acssensors.0C00397 |
0.334 |
|
| 2020 |
Wesslowski J, Kozielewicz P, Wang X, Cui H, Schihada H, Kranz D, Karuna M P, Levkin P, Gross JC, Boutros M, Schulte G, Davidson G. eGFP-tagged Wnt-3a enables functional analysis of Wnt trafficking and signaling and kinetic assessment of Wnt binding to full-length Frizzled. The Journal of Biological Chemistry. PMID 32381507 DOI: 10.1074/Jbc.Ra120.012892 |
0.57 |
|
| 2020 |
Kozielewicz P, Turku A, Bowin CF, Petersen J, Valnohova J, Cañizal MCA, Ono Y, Inoue A, Hoffmann C, Schulte G. Structural insight into small molecule action on Frizzleds. Nature Communications. 11: 414. PMID 31964872 DOI: 10.1038/S41467-019-14149-3 |
0.371 |
|
| 2019 |
Tebroke J, Lieverse JE, Säfholm J, Schulte G, Nilsson G, Rönnberg E. Wnt-3a Induces Cytokine Release in Human Mast Cells. Cells. 8. PMID 31683769 DOI: 10.3390/Cells8111372 |
0.475 |
|
| 2019 |
Kozielewicz P, Turku A, Schulte G. Molecular Pharmacology of Class F Receptor Activation. Molecular Pharmacology. PMID 31591260 DOI: 10.1124/Mol.119.117986 |
0.39 |
|
| 2019 |
Bowin CF, Inoue A, Schulte G. WNT-3A-induced β-catenin signaling does not require signaling through heterotrimeric G proteins. The Journal of Biological Chemistry. PMID 31235524 DOI: 10.1074/Jbc.Ac119.009412 |
0.548 |
|
| 2019 |
Schulte G, Kozielewicz P. Structural insight into Class F receptors - what have we learnt regarding agonist-induced activation? Basic & Clinical Pharmacology & Toxicology. PMID 30925000 DOI: 10.1111/Bcpt.13235 |
0.382 |
|
| 2019 |
Wright SC, Kozielewicz P, Kowalski-Jahn M, Petersen J, Bowin CF, Slodkowicz G, Marti-Solano M, Rodríguez D, Hot B, Okashah N, Strakova K, Valnohova J, Babu MM, Lambert NA, Carlsson J, ... Schulte G, et al. A conserved molecular switch in Class F receptors regulates receptor activation and pathway selection. Nature Communications. 10: 667. PMID 30737406 DOI: 10.1038/S41467-019-08630-2 |
0.346 |
|
| 2019 |
Arthofer E, Dijksterhuis J, Hot B, Kozielewicz P, Lauth M, Olofsson J, Petersen J, Polonio T, Schulte G, Strakova K, Valnohova J, Wright S. Class Frizzled GPCRs (version 2019.4) in the IUPHAR/BPS Guide to Pharmacology Database Iuphar/Bps Guide to Pharmacology Cite. 2019. DOI: 10.2218/gtopdb/f25/2019.4 |
0.438 |
|
| 2018 |
Wright SC, Cañizal MCA, Benkel T, Simon K, Le Gouill C, Matricon P, Namkung Y, Lukasheva V, König GM, Laporte SA, Carlsson J, Kostenis E, Bouvier M, Schulte G, Hoffmann C. FZD is a Gα-coupled receptor that exhibits the functional hallmarks of prototypical GPCRs. Science Signaling. 11. PMID 30514810 DOI: 10.1126/Scisignal.Aar5536 |
0.527 |
|
| 2018 |
Strakova K, Kowalski-Jahn M, Gybel T, Valnohova J, Dhople VM, Harnoš J, Bernatik O, Sri Ganji R, Zdrahal Z, Mulder J, Lindskog C, Bryja V, Schulte G. Dishevelled enables casein kinase 1-mediated phosphorylation of Frizzled 6 required for cell membrane localization. The Journal of Biological Chemistry. PMID 30309985 DOI: 10.1074/Jbc.Ra118.004656 |
0.682 |
|
| 2018 |
Valnohova J, Kowalski-Jahn M, Sunahara RK, Schulte G. Functional dissection of the N-terminal extracellular domains of Frizzled 6 reveals their roles for receptor localization and Dishevelled recruitment. The Journal of Biological Chemistry. PMID 30237173 DOI: 10.1074/Jbc.Ra118.004763 |
0.367 |
|
| 2018 |
Schulte G, Wright SC. Frizzleds as GPCRs - More Conventional Than We Thought! Trends in Pharmacological Sciences. PMID 30049420 DOI: 10.1016/J.Tips.2018.07.001 |
0.477 |
|
| 2017 |
Schulte G, Bryja V. WNT signalling: mechanisms and therapeutic opportunities. British Journal of Pharmacology. 174: 4543-4546. PMID 29235106 DOI: 10.1111/Bph.14065 |
0.598 |
|
| 2017 |
Petersen J, Wright SC, Rodríguez D, Matricon P, Lahav N, Vromen A, Friedler A, Strömqvist J, Wennmalm S, Carlsson J, Schulte G. Agonist-induced dimer dissociation as a macromolecular step in G protein-coupled receptor signaling. Nature Communications. 8: 226. PMID 28790300 DOI: 10.1038/S41467-017-00253-9 |
0.49 |
|
| 2017 |
Strakova K, Matricon P, Yokota C, Arthofer E, Bernatik O, Rodriguez D, Arenas E, Carlsson J, Bryja V, Schulte G. The tyrosine Y250(2.39) in Frizzled 4 defines a conserved motif important for structural integrity of the receptor and recruitment of Disheveled. Cellular Signalling. PMID 28668722 DOI: 10.1016/J.Cellsig.2017.06.018 |
0.738 |
|
| 2017 |
Hot B, Valnohova J, Arthofer E, Simon K, Shin J, Uhlén M, Kostenis E, Mulder J, Schulte G. FZD10-Gα13 signalling axis points to a role of FZD10 in CNS angiogenesis. Cellular Signalling. PMID 28126591 DOI: 10.1016/J.Cellsig.2017.01.023 |
0.485 |
|
| 2016 |
Cervenka I, Valnohova J, Bernatik O, Harnos J, Radsetoulal M, Sedova K, Hanakova K, Potesil D, Sedlackova M, Salasova A, Steinhart Z, Angers S, Schulte G, Hampl A, Zdrahal Z, et al. Dishevelled is a NEK2 kinase substrate controlling dynamics of centrosomal linker proteins. Proceedings of the National Academy of Sciences of the United States of America. PMID 27486244 DOI: 10.1073/Pnas.1608783113 |
0.653 |
|
| 2016 |
Arthofer E, Hot B, Petersen J, Strakova K, Jager S, Grundmann M, Kostenis E, Gutkind SJ, Schulte G. WNT stimulation dissociates a Frizzled 4 inactive state complex with Gα12/13. Molecular Pharmacology. PMID 27458145 DOI: 10.1124/Mol.116.104919 |
0.558 |
|
| 2015 |
Schulte G. WNT signaling in microglia and the glioma microenvironment. Springerplus. 4: L50. PMID 27386213 DOI: 10.1186/2193-1801-4-S1-L50 |
0.473 |
|
| 2015 |
Dijksterhuis JP, Arthofer E, Marinescu VD, Nelander S, Uhlén M, Pontén F, Mulder J, Schulte G. High levels of WNT-5A in human glioma correlate with increased presence of tumour-associated microglia/monocytes. Experimental Cell Research. PMID 26511503 DOI: 10.1016/J.Yexcr.2015.10.022 |
0.45 |
|
| 2015 |
Schulte G. Frizzleds and WNT/β-catenin signaling--The black box of ligand-receptor selectivity, complex stoichiometry and activation kinetics. European Journal of Pharmacology. 763: 191-5. PMID 26003275 DOI: 10.1016/J.Ejphar.2015.05.031 |
0.501 |
|
| 2015 |
Kaucká M, Petersen J, Janovská P, Radaszkiewicz T, Smy?ková L, Daulat AM, Borg JP, Schulte G, Bryja V. Asymmetry of VANGL2 in migrating lymphocytes as a tool to monitor activity of the mammalian WNT/planar cell polarity pathway. Cell Communication and Signaling : Ccs. 13: 2. PMID 25627785 DOI: 10.1186/S12964-014-0079-1 |
0.629 |
|
| 2015 |
Dijksterhuis JP, Baljinnyam B, Stanger K, Sercan HO, Ji Y, Andres O, Rubin JS, Hannoush RN, Schulte G. Systematic mapping of WNT-FZD protein interactions reveals functional selectivity by distinct WNT-FZD pairs. The Journal of Biological Chemistry. 290: 6789-98. PMID 25605717 DOI: 10.1074/Jbc.M114.612648 |
0.515 |
|
| 2014 |
Kilander MB, Dahlström J, Schulte G. Assessment of Frizzled 6 membrane mobility by FRAP supports G protein coupling and reveals WNT-Frizzled selectivity. Cellular Signalling. 26: 1943-9. PMID 24873871 DOI: 10.1016/J.Cellsig.2014.05.012 |
0.552 |
|
| 2014 |
Kilander MB, Petersen J, Andressen KW, Ganji RS, Levy FO, Schuster J, Dahl N, Bryja V, Schulte G. Disheveled regulates precoupling of heterotrimeric G proteins to Frizzled 6. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 28: 2293-305. PMID 24500924 DOI: 10.1096/Fj.13-246363 |
0.652 |
|
| 2014 |
Kríz V, Pospíchalová V, Masek J, Kilander MB, Slavík J, Tanneberger K, Schulte G, Machala M, Kozubík A, Behrens J, Bryja V. β-arrestin promotes Wnt-induced low density lipoprotein receptor-related protein 6 (Lrp6) phosphorylation via increased membrane recruitment of Amer1 protein. The Journal of Biological Chemistry. 289: 1128-41. PMID 24265322 DOI: 10.1074/Jbc.M113.498444 |
0.651 |
|
| 2014 |
Yang J, Zheng X, Haugen F, Darè E, Lövdahl C, Schulte G, Fredholm BB, Valen G. Adenosine increases LPS-induced nuclear factor kappa B activation in smooth muscle cells via an intracellular mechanism and modulates it via actions on adenosine receptors. Acta Physiologica (Oxford, England). 210: 590-9. PMID 24119187 DOI: 10.1111/Apha.12176 |
0.497 |
|
| 2014 |
Dijksterhuis JP, Petersen J, Schulte G. WNT/Frizzled signalling: receptor-ligand selectivity with focus on FZD-G protein signalling and its physiological relevance: IUPHAR Review 3. British Journal of Pharmacology. 171: 1195-209. PMID 24032637 DOI: 10.1111/Bph.12364 |
0.5 |
|
| 2013 |
Halleskog C, Schulte G. WNT-3A and WNT-5A counteract lipopolysaccharide-induced pro-inflammatory changes in mouse primary microglia. Journal of Neurochemistry. 125: 803-8. PMID 23534675 DOI: 10.1111/Jnc.12250 |
0.421 |
|
| 2013 |
Halleskog C, Schulte G. Pertussis toxin-sensitive heterotrimeric G(αi/o) proteins mediate WNT/β-catenin and WNT/ERK1/2 signaling in mouse primary microglia stimulated with purified WNT-3A. Cellular Signalling. 25: 822-8. PMID 23266471 DOI: 10.1016/J.Cellsig.2012.12.006 |
0.569 |
|
| 2012 |
Halleskog C, Dijksterhuis JP, Kilander MB, Becerril-Ortega J, Villaescusa JC, Lindgren E, Arenas E, Schulte G. Heterotrimeric G protein-dependent WNT-5A signaling to ERK1/2 mediates distinct aspects of microglia proinflammatory transformation. Journal of Neuroinflammation. 9: 111. PMID 22647544 DOI: 10.1186/1742-2094-9-111 |
0.817 |
|
| 2012 |
Wiklund A, Gustavsson D, Ebberyd A, Sundman E, Schulte G, Fagerlund MJ, Eriksson LI. Prolonged attenuation of acetylcholine-induced phosphorylation of extracellular signal-regulated kinase 1/2 following sevoflurane exposure Acta Anaesthesiologica Scandinavica. 56: 608-615. PMID 22288781 DOI: 10.1111/J.1399-6576.2011.02632.X |
0.377 |
|
| 2012 |
Wiklund A, Gustavsson D, Ebberyd A, Jonsson Fagerlund M, Eriksson LI, Schulte G. Effects of sevoflurane exposure on muscarinic acetylcholine receptor gene expression, protein amount and cellular localization European Journal of Anaesthesiology. 29: 144. DOI: 10.1097/00003643-201206001-00473 |
0.328 |
|
| 2011 |
Schulte G, Shenoy SK. β-Arrestin and dishevelled coordinate biased signaling. Proceedings of the National Academy of Sciences of the United States of America. 108: 19839-40. PMID 22123954 DOI: 10.1073/Pnas.1117444108 |
0.509 |
|
| 2011 |
Fröjmark AS, Schuster J, Sobol M, Entesarian M, Kilander MB, Gabrikova D, Nawaz S, Baig SM, Schulte G, Klar J, Dahl N. Mutations in Frizzled 6 cause isolated autosomal-recessive nail dysplasia. American Journal of Human Genetics. 88: 852-60. PMID 21665003 DOI: 10.1016/J.Ajhg.2011.05.013 |
0.394 |
|
| 2011 |
Kilander MBC, Halleskog C, Schulte G. Recombinant WNTs differentially activate β-catenin-dependent and -independent signalling in mouse microglia-like cells Acta Physiologica. 203: 363-372. PMID 21557822 DOI: 10.1111/J.1748-1716.2011.02324.X |
0.541 |
|
| 2011 |
Mulder J, Zilberter M, Pasquaré SJ, Alpár A, Schulte G, Ferreira SG, Köfalvi A, MartÃn-Moreno AM, Keimpema E, Tanila H, Watanabe M, Mackie K, Hortobágyi T, de Ceballos ML, Harkany T. Molecular reorganization of endocannabinoid signalling in Alzheimer's disease. Brain : a Journal of Neurology. 134: 1041-60. PMID 21459826 DOI: 10.1093/Brain/Awr046 |
0.35 |
|
| 2011 |
Tanneberger K, Pfister AS, Brauburger K, Schneikert J, Hadjihannas MV, Kriz V, Schulte G, Bryja V, Behrens J. Amer1/WTX couples Wnt-induced formation of PtdIns(4,5)P2 to LRP6 phosphorylation. The Embo Journal. 30: 1433-43. PMID 21304492 DOI: 10.1038/Emboj.2011.28 |
0.666 |
|
| 2011 |
Bernatik O, Ganji RS, Dijksterhuis JP, Konik P, Cervenka I, Polonio T, Krejci P, Schulte G, Bryja V. Sequential activation and inactivation of Dishevelled in the Wnt/beta-catenin pathway by casein kinases. The Journal of Biological Chemistry. 286: 10396-410. PMID 21285348 DOI: 10.1074/jbc.M110.169870 |
0.655 |
|
| 2011 |
Kilander MB, Dijksterhuis JP, Ganji RS, Bryja V, Schulte G. WNT-5A stimulates the GDP/GTP exchange at pertussis toxin-sensitive heterotrimeric G proteins. Cellular Signalling. 23: 550-4. PMID 21070854 DOI: 10.1016/J.Cellsig.2010.11.004 |
0.667 |
|
| 2011 |
Červenka I, Wolf J, Mašek J, Krejci P, Wilcox WR, Kozubík A, Schulte G, Gutkind JS, Bryja V. Mitogen-activated protein kinases promote WNT/beta-catenin signaling via phosphorylation of LRP6. Molecular and Cellular Biology. 31: 179-89. PMID 20974802 DOI: 10.1128/Mcb.00550-10 |
0.673 |
|
| 2011 |
Halleskog C, Mulder J, Dahlström J, Mackie K, Hortobágyi T, Tanila H, Kumar Puli L, Färber K, Harkany T, Schulte G. WNT signaling in activated microglia is proinflammatory. Glia. 59: 119-31. PMID 20967887 DOI: 10.1002/Glia.21081 |
0.509 |
|
| 2011 |
Schulte G, Bryja V, Schambony A. 19thActa Physiologicainternational symposium ‘WNT Signaling in Physiology and Disease’- a long way from developmental biology to physiology Acta Physiologica. 204: 6-7. DOI: 10.1111/J.1748-1716.2011.02326.X |
0.615 |
|
| 2010 |
Schulte G. International Union of Basic and Clinical Pharmacology. LXXX. The class Frizzled receptors. Pharmacological Reviews. 62: 632-67. PMID 21079039 DOI: 10.1124/Pr.110.002931 |
0.478 |
|
| 2010 |
Fagerlund MJ, Kåhlin J, Ebberyd A, Schulte G, Mkrtchian S, Eriksson LI. The human carotid body: expression of oxygen sensing and signaling genes of relevance for anesthesia. Anesthesiology. 113: 1270-9. PMID 20980909 DOI: 10.1097/Aln.0B013E3181Fac061 |
0.334 |
|
| 2010 |
Li L, Hao JX, Fredholm BB, Schulte G, Wiesenfeld-Hallin Z, Xu XJ. Peripheral adenosine A2A receptors are involved in carrageenan-induced mechanical hyperalgesia in mice. Neuroscience. 170: 923-8. PMID 20678550 DOI: 10.1016/J.Neuroscience.2010.07.045 |
0.554 |
|
| 2010 |
Lindqvist M, Horn Z, Bryja V, Schulte G, Papachristou P, Ajima R, Dyberg C, Arenas E, Yamaguchi TP, Lagercrantz H, Ringstedt T. Vang-like protein 2 and Rac1 interact to regulate adherens junctions. Journal of Cell Science. 123: 472-83. PMID 20067994 DOI: 10.1242/Jcs.048074 |
0.704 |
|
| 2010 |
Schulte G, Schambony A, Bryja V. beta-Arrestins - scaffolds and signalling elements essential for WNT/Frizzled signalling pathways? British Journal of Pharmacology. 159: 1051-8. PMID 19888962 DOI: 10.1111/J.1476-5381.2009.00466.X |
0.699 |
|
| 2008 |
Bryja V, Schambony A, Cajánek L, Dominguez I, Arenas E, Schulte G. Beta-arrestin and casein kinase 1/2 define distinct branches of non-canonical WNT signalling pathways. Embo Reports. 9: 1244-50. PMID 18953287 DOI: 10.1038/Embor.2008.193 |
0.788 |
|
| 2008 |
Brand F, Klutz AM, Jacobson KA, Fredholm BB, Schulte G. Adenosine A(2A) receptor dynamics studied with the novel fluorescent agonist Alexa488-APEC. European Journal of Pharmacology. 590: 36-42. PMID 18603240 DOI: 10.1016/J.Ejphar.2008.05.036 |
0.616 |
|
| 2007 |
Schulte G, Bryja V. The Frizzled family of unconventional G-protein-coupled receptors. Trends in Pharmacological Sciences. 28: 518-25. PMID 17884187 DOI: 10.1016/J.Tips.2007.09.001 |
0.672 |
|
| 2007 |
Daré E, Schulte G, Karovic O, Hammarberg C, Fredholm BB. Modulation of glial cell functions by adenosine receptors. Physiology & Behavior. 92: 15-20. PMID 17574632 DOI: 10.1016/J.Physbeh.2007.05.031 |
0.598 |
|
| 2007 |
Bryja V, Cajánek L, Grahn A, Schulte G. Inhibition of endocytosis blocks Wnt signalling to beta-catenin by promoting dishevelled degradation. Acta Physiologica (Oxford, England). 190: 55-61. PMID 17428233 DOI: 10.1111/J.1365-201X.2007.01688.X |
0.82 |
|
| 2007 |
Schulte G, Levy FO. Novel aspects of G-protein-coupled receptor signalling--different ways to achieve specificity. Acta Physiologica (Oxford, England). 190: 33-8. PMID 17428230 DOI: 10.1111/J.1365-201X.2007.01696.X |
0.519 |
|
| 2007 |
Schulte G, Fredholm B. A Nordic meeting on G-protein-coupled receptors: From molecular aspects to novel therapy Acta Physiologica. 190: 1. PMID 17428226 DOI: 10.1111/J.1365-201X.2007.01686.X |
0.491 |
|
| 2007 |
Bryja V, Gradl D, Schambony A, Arenas E, Schulte G. Beta-arrestin is a necessary component of Wnt/beta-catenin signaling in vitro and in vivo. Proceedings of the National Academy of Sciences of the United States of America. 104: 6690-5. PMID 17426148 DOI: 10.1073/Pnas.0611356104 |
0.724 |
|
| 2007 |
Bryja V, Schulte G, Rawal N, Grahn A, Arenas E. Wnt-5a induces Dishevelled phosphorylation and dopaminergic differentiation via a CK1-dependent mechanism. Journal of Cell Science. 120: 586-95. PMID 17244647 DOI: 10.1242/Jcs.03368 |
0.799 |
|
| 2007 |
Bryja V, Schulte G, Arenas E. Wnt-3a utilizes a novel low dose and rapid pathway that does not require casein kinase 1-mediated phosphorylation of Dvl to activate beta-catenin. Cellular Signalling. 19: 610-6. PMID 17027228 DOI: 10.1016/J.Cellsig.2006.08.011 |
0.765 |
|
| 2005 |
Berghuis P, Dobszay MB, Wang X, Spano S, Ledda F, Sousa KM, Schulte G, Ernfors P, Mackie K, Paratcha G, Hurd YL, Harkany T. Endocannabinoids regulate interneuron migration and morphogenesis by transactivating the TrkB receptor. Proceedings of the National Academy of Sciences of the United States of America. 102: 19115-20. PMID 16357196 DOI: 10.1073/Pnas.0509494102 |
0.407 |
|
| 2005 |
Hemström TH, Joseph B, Schulte G, Lewensohn R, Zhivotovsky B. PKC 412 sensitizes U1810 non-small cell lung cancer cells to DNA damage. Experimental Cell Research. 305: 200-13. PMID 15777800 DOI: 10.1016/J.Yexcr.2004.12.017 |
0.307 |
|
| 2005 |
Schulte G, Bryja V, Rawal N, Castelo-Branco G, Sousa KM, Arenas E. Purified Wnt-5a increases differentiation of midbrain dopaminergic cells and dishevelled phosphorylation. Journal of Neurochemistry. 92: 1550-3. PMID 15748172 DOI: 10.1111/J.1471-4159.2004.03022.X |
0.77 |
|
| 2004 |
Schulte G, Sommerschild H, Yang J, Tokuno S, Goiny M, Lövdahl C, Johansson B, Fredholm BB, Valen G. Adenosine A receptors are necessary for protection of the murine heart by remote, delayed adaptation to ischaemia. Acta Physiologica Scandinavica. 182: 133-43. PMID 15450109 DOI: 10.1111/J.1365-201X.2004.01350.X |
0.574 |
|
| 2004 |
Hammarberg C, Fredholm BB, Schulte G. Adenosine A3 receptor-mediated regulation of p38 and extracellular-regulated kinase ERK1/2 via phosphatidylinositol-3'-kinase. Biochemical Pharmacology. 67: 129-34. PMID 14667935 DOI: 10.1016/J.Bcp.2003.08.031 |
0.662 |
|
| 2004 |
Hammarberg C, Fredholm BB, Schulte G. Adenosine A3 receptor-mediated regulation of p38 and extracellular-regulated kinase ERK1/2 via phosphatidylinositol-3′-kinase Biochemical Pharmacology. 67: 129-134. DOI: 10.1016/j.bcp.2003.08.031 |
0.56 |
|
| 2003 |
Schulte G, Robertson B, Fredholm BB, DeLander GE, Shortland P, Molander C. Distribution of antinociceptive adenosine A1 receptors in the spinal cord dorsal horn, and relationship to primary afferents and neuronal subpopulations. Neuroscience. 121: 907-16. PMID 14580941 DOI: 10.1016/S0306-4522(03)00480-9 |
0.558 |
|
| 2003 |
Schulte G, Fredholm BB. The G(s)-coupled adenosine A(2B) receptor recruits divergent pathways to regulate ERK1/2 and p38. Experimental Cell Research. 290: 168-76. PMID 14516797 DOI: 10.1016/S0014-4827(03)00324-0 |
0.59 |
|
| 2003 |
Hammarberg C, Schulte G, Fredholm BB. Evidence for functional adenosine A3 receptors in microglia cells. Journal of Neurochemistry. 86: 1051-4. PMID 12887702 DOI: 10.1046/J.1471-4159.2003.01919.X |
0.645 |
|
| 2003 |
Lynge J, Schulte G, Nordsborg N, Fredholm BB, Hellsten Y. Adenosine A 2B receptors modulate cAMP levels and induce CREB but not ERK1/2 and p38 phosphorylation in rat skeletal muscle cells. Biochemical and Biophysical Research Communications. 307: 180-7. PMID 12849998 DOI: 10.1016/S0006-291X(03)01125-2 |
0.552 |
|
| 2003 |
Schulte G, Fredholm BB. Signalling from adenosine receptors to mitogen-activated protein kinases. Cellular Signalling. 15: 813-27. PMID 12834807 DOI: 10.1016/S0898-6568(03)00058-5 |
0.622 |
|
| 2003 |
Fredholm BB, Halldner L, Johansson C, Schulte G, Lövdahl C, Thorén P, Dunwiddie TV, Masino SA, Poelchen W, Diao L, Illes P, Zahniser NR, Valen G, Tokuno S, Sommerschild H, et al. Consequences of eliminating adenosine A1 receptors in mice Drug Development Research. 58: 350-353. DOI: 10.1002/Ddr.10170 |
0.461 |
|
| 2002 |
Schulte G, Fredholm BB. Signaling pathway from the human adenosine A(3) receptor expressed in Chinese hamster ovary cells to the extracellular signal-regulated kinase 1/2. Molecular Pharmacology. 62: 1137-46. PMID 12391277 DOI: 10.1124/Mol.62.5.1137 |
0.632 |
|
| 2002 |
Schulte G, Fredholm BB. Diverse inhibitors of intracellular signalling act as adenosine receptor antagonists. Cellular Signalling. 14: 109-13. PMID 11781134 DOI: 10.1016/S0898-6568(01)00228-5 |
0.598 |
|
| 2002 |
Sommerschild HT, Fredholm BB, Schulte G, Jagerbrink T, Lövdahl C, Tokuno S, Valen G. A1 receptors mediate delayed remote preconditioning, possible involvement of mapk Journal of Molecular and Cellular Cardiology. 34: A59. DOI: 10.1016/S0022-2828(02)90960-0 |
0.486 |
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| 2001 |
Fredholm BB, Irenius E, Kull B, Schulte G. Comparison of the potency of adenosine as an agonist at human adenosine receptors expressed in Chinese hamster ovary cells. Biochemical Pharmacology. 61: 443-8. PMID 11226378 DOI: 10.1016/S0006-2952(00)00570-0 |
0.6 |
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| 2001 |
Fredholm BB, Arslan G, Halldner L, Kull B, Schulte G, Ådén U, Svenningsson P. Adenosine receptor signaling in vitro and in vivo Drug Development Research. 52: 274-282. DOI: 10.1002/Ddr.1124 |
0.681 |
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| 2000 |
Fredholm BB, Arslan G, Halldner L, Kull B, Schulte G, Wasserman W. Structure and function of adenosine receptors and their genes. Naunyn-Schmiedeberg's Archives of Pharmacology. 362: 364-74. PMID 11111830 DOI: 10.1007/S002100000313 |
0.624 |
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| 2000 |
Schulte G, Fredholm BB. Human Adenosine A1, A2A, A2B, and A3 Receptors Expressed in Chinese Hamster Ovary Cells All Mediate the Phosphorylation of Extracellular-Regulated Kinase 1/2 Molecular Pharmacology. 58: 477-482. DOI: 10.1124/Mol.58.3.477 |
0.626 |
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| Low-probability matches (unlikely to be authored by this person) |
| 2021 |
Turku A, Schihada H, Kozielewicz P, Bowin CF, Schulte G. Residue 6.43 defines receptor function in class F GPCRs. Nature Communications. 12: 3919. PMID 34168128 DOI: 10.1038/s41467-021-24004-z |
0.298 |
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| 2004 |
Harkany T, Holmgren C, Härtig W, Qureshi T, Chaudhry FA, Storm-Mathisen J, Dobszay MB, Berghuis P, Schulte G, Sousa KM, Fremeau RT, Edwards RH, Mackie K, Ernfors P, Zilberter Y. Endocannabinoid-independent retrograde signaling at inhibitory synapses in layer 2/3 of neocortex: involvement of vesicular glutamate transporter 3. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 4978-88. PMID 15163690 DOI: 10.1523/Jneurosci.4884-03.2004 |
0.289 |
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| 2019 |
Kozielewicz P, Bowin CF, Turku A, Schulte G. A NanoBRET-based binding assay for Smoothened allows real time analysis of ligand binding and distinction of two binding sites for BODIPY-cyclopamine. Molecular Pharmacology. PMID 31707356 DOI: 10.1124/Mol.119.118158 |
0.279 |
|
| 1999 |
Robertson B, Schulte G, Elde R, Grant G. Effects of sciatic nerve injuries on δ-opioid receptor and substance P immunoreactivities in the superficial dorsal horn of the rat European Journal of Pain. 3: 115-129. DOI: 10.1053/Eujp.1998.0104 |
0.267 |
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| 2004 |
Berghuis P, Dobszay MB, Sousa KM, Schulte G, Mager PP, Härtig W, Görcs TJ, Zilberter Y, Ernfors P, Harkany T. Brain-derived neurotrophic factor controls functional differentiation and microcircuit formation of selectively isolated fast-spiking GABAergic interneurons. The European Journal of Neuroscience. 20: 1290-306. PMID 15341601 DOI: 10.1111/J.1460-9568.2004.03561.X |
0.248 |
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| 2014 |
Persson A, Sim SC, Virding S, Onishchenko N, Schulte G, Ingelman-Sundberg M. Decreased hippocampal volume and increased anxiety in a transgenic mouse model expressing the human CYP2C19 gene. Molecular Psychiatry. 19: 733-741. PMID 23877834 DOI: 10.1038/Mp.2013.89 |
0.23 |
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| 2021 |
Schihada H, Shekhani R, Schulte G. Quantitative assessment of constitutive G protein-coupled receptor activity with BRET-based G protein biosensors. Science Signaling. 14: eabf1653. PMID 34516756 DOI: 10.1126/scisignal.abf1653 |
0.222 |
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| 2024 |
Kinsolving J, Bous J, Kozielewicz P, Košenina S, Shekhani R, Grätz L, Masuyer G, Wang Y, Stenmark P, Dong M, Schulte G. Structural and functional insight into the interaction of Clostridioides difficile toxin B and FZD. Cell Reports. 43: 113727. PMID 38308843 DOI: 10.1016/j.celrep.2024.113727 |
0.214 |
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| 2016 |
Strömberg A, Olsson K, Dijksterhuis JP, Rullman E, Schulte G, Gustafsson T. CX3CL1--a macrophage chemoattractant induced by a single bout of exercise in human skeletal muscle. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 310: R297-304. PMID 26632602 DOI: 10.1152/Ajpregu.00236.2015 |
0.213 |
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| 2023 |
Oliva-Vilarnau N, Beusch CM, Sabatier P, Sakaraki E, Tjaden A, Graetz L, Büttner FA, Dorotea D, Nguyen M, Bergqvist F, Sundström Y, Müller S, Zubarev RA, Schulte G, Tredup C, et al. Wnt/β-catenin and NFκB signaling synergize to trigger growth-factor-free regeneration of adult primary human hepatocytes. Hepatology (Baltimore, Md.). PMID 37870288 DOI: 10.1097/HEP.0000000000000648 |
0.212 |
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| 2022 |
Kozielewicz P, Schulte G. NanoBRET and NanoBiT/BRET-Based Ligand Binding Assays Permit Quantitative Assessment of Small Molecule Ligand Binding to Smoothened. Methods in Molecular Biology (Clifton, N.J.). 2374: 195-204. PMID 34562254 DOI: 10.1007/978-1-0716-1701-4_17 |
0.196 |
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| 2021 |
Alexander SP, Christopoulos A, Davenport AP, Kelly E, Mathie A, Peters JA, Veale EL, Armstrong JF, Faccenda E, Harding SD, Pawson AJ, Southan C, Davies JA, Abbracchio MP, Alexander W, ... ... Schulte G, et al. THE CONCISE GUIDE TO PHARMACOLOGY 2021/22: G protein-coupled receptors. British Journal of Pharmacology. 178: S27-S156. PMID 34529832 DOI: 10.1111/bph.15538 |
0.174 |
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| 2023 |
Alexander SPH, Christopoulos A, Davenport AP, Kelly E, Mathie AA, Peters JA, Veale EL, Armstrong JF, Faccenda E, Harding SD, Davies JA, Abbracchio MP, Abraham G, Agoulnik A, Alexander W, ... ... Schulte G, et al. The Concise Guide to PHARMACOLOGY 2023/24: G protein-coupled receptors. British Journal of Pharmacology. S23-S144. PMID 38123151 DOI: 10.1111/bph.16177 |
0.173 |
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| 2023 |
Kowalski-Jahn M, Schihada H, Schulte G. Conformational GPCR BRET Sensors Based on Bioorthogonal Labeling of Noncanonical Amino Acids. Methods in Molecular Biology (Clifton, N.J.). 2676: 201-213. PMID 37277635 DOI: 10.1007/978-1-0716-3251-2_15 |
0.144 |
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| 2024 |
Scharf MM, Humphrys LJ, Berndt S, Di Pizio A, Lehmann J, Liebscher I, Nicoli A, Niv MY, Peri L, Schihada H, Schulte G. The dark sides of the GPCR tree - research progress on understudied GPCRs. British Journal of Pharmacology. PMID 38339984 DOI: 10.1111/bph.16325 |
0.12 |
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| 2021 |
Xu L, Chen B, Schihada H, Wright SC, Turku A, Wu Y, Han GW, Kowalski-Jahn M, Kozielewicz P, Bowin CF, Zhang X, Li C, Bouvier M, Schulte G, Xu F. Cryo-EM structure of constitutively active human Frizzled 7 in complex with heterotrimeric G. Cell Research. PMID 34239071 DOI: 10.1038/s41422-021-00525-6 |
0.118 |
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| 2021 |
Kowalski-Jahn M, Schihada H, Turku A, Huber T, Sakmar TP, Schulte G. Frizzled BRET sensors based on bioorthogonal labeling of unnatural amino acids reveal WNT-induced dynamics of the cysteine-rich domain. Science Advances. 7: eabj7917. PMID 34757789 DOI: 10.1126/sciadv.abj7917 |
0.067 |
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| 2021 |
Zhou Y, Arribas GH, Turku A, Jürgenson T, Mkrtchian S, Krebs K, Wang Y, Svobodova B, Milani L, Schulte G, Korabecny J, Gastaldello S, Lauschke VM. Rare genetic variability in human drug target genes modulates drug response and can guide precision medicine. Science Advances. 7: eabi6856. PMID 34516913 DOI: 10.1126/sciadv.abi6856 |
0.028 |
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| Hide low-probability matches. |