Frank Heppner - Publications

Affiliations: 
Neuropathology Charité - Universitätsmedizin Berlin, Germany 

68/220 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Levites Y, Dammer EB, Ran Y, Tsering W, Duong D, Abreha M, Gadhavi J, Lolo K, Trejo-Lopez J, Phillips JL, Iturbe A, Erqiuzi A, Moore BD, Ryu D, Natu A, ... ... Heppner FL, et al. Aβ Amyloid Scaffolds the Accumulation of Matrisome and Additional Proteins in Alzheimer's Disease. Biorxiv : the Preprint Server For Biology. PMID 38076912 DOI: 10.1101/2023.11.29.568318  0.672
2023 Saetzler V, Riet T, Schienke A, Henschel P, Freitag K, Haake A, Heppner FL, Buitrago-Molina LE, Noyan F, Jaeckel E, Hardtke-Wolenski M. Development of Beta-Amyloid-Specific CAR-Tregs for the Treatment of Alzheimer's Disease. Cells. 12. PMID 37626926 DOI: 10.3390/cells12162115  0.32
2023 Caesar I, Nilsson KPR, Hammarstrom P, Lindgren M, Prokop S, Heppner FL, Schmeidler J, Haroutunian V, Holtzman DM, Hof PR, Gandy S. ApoE Alzheimer's Disease Aβ-amyloid plaque morphology varies according to APOE isotype. Research Square. PMID 36798327 DOI: 10.21203/rs.3.rs-2524641/v1  0.653
2022 Paolicelli RC, Sierra A, Stevens B, Tremblay ME, Aguzzi A, Ajami B, Amit I, Audinat E, Bechmann I, Bennett M, Bennett F, Bessis A, Biber K, Bilbo S, Blurton-Jones M, ... ... Heppner FL, et al. Microglia states and nomenclature: A field at its crossroads. Neuron. 110: 3458-3483. PMID 36327895 DOI: 10.1016/j.neuron.2022.10.020  0.673
2022 Freitag K, Sterczyk N, Wendlinger S, Obermayer B, Schulz J, Farztdinov V, Mülleder M, Ralser M, Houtman J, Fleck L, Braeuning C, Sansevrino R, Hoffmann C, Milovanovic D, Sigrist SJ, ... ... Heppner FL, et al. Spermidine reduces neuroinflammation and soluble amyloid beta in an Alzheimer's disease mouse model. Journal of Neuroinflammation. 19: 172. PMID 35780157 DOI: 10.1186/s12974-022-02534-7  0.333
2020 Drost N, Houtman J, Cseresnyés Z, Niesner R, Rinnenthal JL, Miller KR, Prokop S, Heppner FL. The Amyloid-beta rich CNS environment alters myeloid cell functionality independent of their origin. Scientific Reports. 10: 7152. PMID 32346002 DOI: 10.1038/S41598-020-63989-3  0.79
2020 Eede P, Obst J, Benke E, Yvon-Durocher G, Richard BC, Gimber N, Schmoranzer J, Böddrich A, Wanker EE, Prokop S, Heppner FL. Interleukin-12/23 deficiency differentially affects pathology in male and female Alzheimer's disease-like mice. Embo Reports. e48530. PMID 32003148 DOI: 10.15252/Embr.201948530  0.663
2018 Mpambani F, Åslund AKO, Lerouge F, Nyström S, Reitan N, Huuse EM, Widerøe M, Chaput F, Monnereau C, Andraud C, Lecouvey M, Handrick S, Prokop S, Heppner FL, Nilsson P, et al. Two-Photon Fluorescence and Magnetic Resonance Specific Imaging of Aβ Amyloid Using Hybrid Nano-GdF Contrast Media. Acs Applied Bio Materials. 1: 462-472. PMID 35016367 DOI: 10.1021/acsabm.8b00191  0.631
2018 Kälin S, Miller KR, Kälin RE, Jendrach M, Witzel C, Heppner FL. CNS myeloid cells critically regulate heat hyperalgesia. The Journal of Clinical Investigation. PMID 29634489 DOI: 10.1172/Jci95305  0.641
2018 Burwinkel M, Lutzenberger M, Heppner FL, Schulz-Schaeffer W, Baier M. Intravenous injection of beta-amyloid seeds promotes cerebral amyloid angiopathy (CAA). Acta Neuropathologica Communications. 6: 23. PMID 29506560 DOI: 10.1186/s40478-018-0511-7  0.317
2017 Krasemann S, Madore C, Cialic R, Baufeld C, Calcagno N, El Fatimy R, Beckers L, O'Loughlin E, Xu Y, Fanek Z, Greco DJ, Smith ST, Tweet G, Humulock Z, Zrzavy T, ... ... Heppner FL, et al. The TREM2-APOE Pathway Drives the Transcriptional Phenotype of Dysfunctional Microglia in Neurodegenerative Diseases. Immunity. 47: 566-581.e9. PMID 28930663 DOI: 10.1016/J.Immuni.2017.08.008  0.794
2017 Wagner LK, Gilling KE, Schormann E, Kloetzel PM, Heppner FL, Krüger E, Prokop S. Immunoproteasome deficiency alters microglial cytokine response and improves cognitive deficits in Alzheimer's disease-like APPPS1 mice. Acta Neuropathologica Communications. 5: 52. PMID 28646899 DOI: 10.1186/S40478-017-0453-5  0.673
2016 Baufeld C, Osterloh A, Prokop S, Miller KR, Heppner FL. High-fat diet-induced brain region-specific phenotypic spectrum of CNS resident microglia. Acta Neuropathologica. PMID 27393312 DOI: 10.1007/S00401-016-1595-4  0.744
2016 Brandenburg S, Müller A, Turkowski K, Radev YT, Rot S, Schmidt C, Bungert AD, Acker G, Schorr A, Hippe A, Miller K, Heppner FL, Homey B, Vajkoczy P. Resident microglia rather than peripheral macrophages promote vascularization in brain tumors and are source of alternative pro-angiogenic factors. Acta Neuropathologica. 131: 365-78. PMID 26718201 DOI: 10.1007/S00401-015-1529-6  0.637
2015 Prokop S, Miller KR, Drost N, Handrick S, Mathur V, Luo J, Wegner A, Wyss-Coray T, Heppner FL. Impact of peripheral myeloid cells on amyloid-β pathology in Alzheimer's disease-like mice. The Journal of Experimental Medicine. 212: 1811-8. PMID 26458768 DOI: 10.1084/Jem.20150479  0.791
2015 Schreiner B, Romanelli E, Liberski P, Ingold-Heppner B, Sobottka-Brillout B, Hartwig T, Chandrasekar V, Johannssen H, Zeilhofer HU, Aguzzi A, Heppner F, Kerschensteiner M, Becher B. Astrocyte Depletion Impairs Redox Homeostasis and Triggers Neuronal Loss in the Adult CNS. Cell Reports. 12: 1377-84. PMID 26299968 DOI: 10.1016/J.Celrep.2015.07.051  0.568
2015 Naumann RK, Ray S, Prokop S, Las L, Heppner FL, Brecht M. Conserved size & periodicity of pyramidal patches in layer 2 of medial/caudal entorhinal cortex. The Journal of Comparative Neurology. PMID 26223342 DOI: 10.1002/Cne.23865  0.578
2015 Nunes JC, Radbruch H, Walz R, Lin K, Stenzel W, Prokop S, Koch A, Heppner FL. The most fulminant course of the Marburg variant of multiple sclerosis-autopsy findings. Multiple Sclerosis (Houndmills, Basingstoke, England). 21: 485-7. PMID 25824955 DOI: 10.1177/1352458514537366  0.614
2015 Johansson LB, Simon R, Bergström G, Eriksson M, Prokop S, Mandenius CF, Heppner FL, Åslund AK, Nilsson KP. An azide functionalized oligothiophene ligand--a versatile tool for multimodal detection of disease associated protein aggregates. Biosensors & Bioelectronics. 63: 204-11. PMID 25089818 DOI: 10.1016/J.Bios.2014.07.042  0.625
2014 Barucker C, Harmeier A, Weiske J, Fauler B, Albring KF, Prokop S, Hildebrand P, Lurz R, Heppner FL, Huber O, Multhaup G. Nuclear translocation uncovers the amyloid peptide Aβ42 as a regulator of gene transcription. The Journal of Biological Chemistry. 289: 20182-91. PMID 24878959 DOI: 10.1074/Jbc.M114.564690  0.655
2014 Langenfurth A, Rinnenthal JL, Vinnakota K, Prinz V, Carlo AS, Stadelmann C, Siffrin V, Peaschke S, Endres M, Heppner F, Glass R, Wolf SA, Kettenmann H. Membrane-type 1 metalloproteinase is upregulated in microglia/brain macrophages in neurodegenerative and neuroinflammatory diseases. Journal of Neuroscience Research. 92: 275-86. PMID 24323769 DOI: 10.1002/Jnr.23288  0.327
2014 Schröder NW, Grieben U, Prokop S, Dekomien G, Epplen JT, Heppner FL, Goebel HH, Stenzel W. Novel γ-sarcoglycan-mutation affects cardiac function and N-terminal dystrophin expression. Muscle & Nerve. 49: 144-5. PMID 23929688 DOI: 10.1002/Mus.23981  0.55
2013 Prokop S, Miller KR, Heppner FL. Microglia actions in Alzheimer’s disease. Acta Neuropathologica. 126: 461-77. PMID 24224195 DOI: 10.1007/S00401-013-1182-X  0.791
2013 Krabbe G, Halle A, Matyash V, Rinnenthal JL, Eom GD, Bernhardt U, Miller KR, Prokop S, Kettenmann H, Heppner FL. Functional impairment of microglia coincides with Beta-amyloid deposition in mice with Alzheimer-like pathology. Plos One. 8: e60921. PMID 23577177 DOI: 10.1371/Journal.Pone.0060921  0.789
2013 Nyström S, Psonka-Antonczyk KM, Ellingsen PG, Johansson LB, Reitan N, Handrick S, Prokop S, Heppner FL, Wegenast-Braun BM, Jucker M, Lindgren M, Stokke BT, Hammarström P, Nilsson KP. Evidence for age-dependent in vivo conformational rearrangement within Aβ amyloid deposits. Acs Chemical Biology. 8: 1128-33. PMID 23521783 DOI: 10.1021/Cb4000376  0.655
2013 Arja K, Sjölander D, Ã…slund A, Prokop S, Heppner FL, Konradsson P, Lindgren M, Hammarström P, Ã…slund KO, Nilsson KP. Enhanced fluorescent assignment of protein aggregates by an oligothiophene-porphyrin-based amyloid ligand. Macromolecular Rapid Communications. 34: 723-30. PMID 23468206 DOI: 10.1002/Marc.201200817  0.647
2013 Klingstedt T, Blechschmidt C, Nogalska A, Prokop S, Häggqvist B, Danielsson O, Engel WK, Askanas V, Heppner FL, Nilsson KP. Luminescent conjugated oligothiophenes for sensitive fluorescent assignment of protein inclusion bodies. Chembiochem : a European Journal of Chemical Biology. 14: 607-16. PMID 23450708 DOI: 10.1002/Cbic.201200731  0.592
2012 Vom Berg J, Prokop S, Miller KR, Obst J, Kälin RE, Lopategui-Cabezas I, Wegner A, Mair F, Schipke CG, Peters O, Winter Y, Becher B, Heppner FL. Inhibition of IL-12/IL-23 signaling reduces Alzheimer's disease-like pathology and cognitive decline. Nature Medicine. 18: 1812-9. PMID 23178247 DOI: 10.1038/Nm.2965  0.756
2012 Varvel NH, Grathwohl SA, Baumann F, Liebig C, Bosch A, Brawek B, Thal DR, Charo IF, Heppner FL, Aguzzi A, Garaschuk O, Ransohoff RM, Jucker M. Microglial repopulation model reveals a robust homeostatic process for replacing CNS myeloid cells. Proceedings of the National Academy of Sciences of the United States of America. 109: 18150-5. PMID 23071306 DOI: 10.1073/Pnas.1210150109  0.585
2012 Gertz K, Kronenberg G, Kälin RE, Baldinger T, Werner C, Balkaya M, Eom GD, Hellmann-Regen J, Kröber J, Miller KR, Lindauer U, Laufs U, Dirnagl U, Heppner FL, Endres M. Essential role of interleukin-6 in post-stroke angiogenesis. Brain : a Journal of Neurology. 135: 1964-80. PMID 22492561 DOI: 10.1093/Brain/Aws075  0.646
2012 Obst J, Prokop S, vom Berg J, Miller K, Kälin R, Lopategui-Cabezas I, Wegner A, Mair F, Winter Y, Becher B, Heppner FL. P4-337: Reducing Alzheimer's disease beta-amyloid and cognitive deficits by manipulating il-12/il-23 signaling Alzheimer's & Dementia. 8: S776-S777. DOI: 10.1016/J.Jalz.2013.08.118  0.744
2012 Eom G, Prokop S, Heppner FL. P4-287: The role of microglia in BETA-AMYLOID immunotherapy Alzheimer's & Dementia. 8: S759-S759. DOI: 10.1016/J.Jalz.2013.08.068  0.604
2011 Opitz E, Koch A, Klingel K, Schmidt F, Prokop S, Rahnefeld A, Sauter M, Heppner FL, Völker U, Kandolf R, Kuckelkorn U, Stangl K, Krüger E, Kloetzel PM, Voigt A. Impairment of immunoproteasome function by β5i/LMP7 subunit deficiency results in severe enterovirus myocarditis. Plos Pathogens. 7: e1002233. PMID 21909276 DOI: 10.1371/Journal.Ppat.1002233  0.636
2011 Schipke CG, Jessen F, Teipel S, Luckhaus C, Wiltfang J, Esselmann H, Frölich L, Maier W, Rüther E, Heppner FL, Prokop S, Heuser I, Peters O. Long-term stability of Alzheimer's disease biomarker proteins in cerebrospinal fluid. Journal of Alzheimer's Disease : Jad. 26: 255-62. PMID 21606567 DOI: 10.3233/Jad-2011-110329  0.626
2011 Prokop S, Heppner FL, Goebel HH, Stenzel W. M2 polarized macrophages and giant cells contribute to myofibrosis in neuromuscular sarcoidosis. The American Journal of Pathology. 178: 1279-86. PMID 21356378 DOI: 10.1016/J.Ajpath.2010.11.065  0.613
2011 Prodinger C, Bunse J, Krüger M, Schiefenhövel F, Brandt C, Laman JD, Greter M, Immig K, Heppner F, Becher B, Bechmann I. CD11c-expressing cells reside in the juxtavascular parenchyma and extend processes into the glia limitans of the mouse nervous system. Acta Neuropathologica. 121: 445-58. PMID 21076838 DOI: 10.1007/S00401-010-0774-Y  0.379
2010 Stenzel W, Prokop S, Kress W, Huppmann S, Loui A, Sarioglu NM, Laing NG, Sparrow JC, Heppner FL, Goebel HH. Fetal akinesia caused by a novel actin filament aggregate myopathy skeletal muscle actin gene (ACTA1) mutation. Neuromuscular Disorders : Nmd. 20: 531-3. PMID 20621480 DOI: 10.1016/J.Nmd.2010.06.008  0.556
2010 Mirrione MM, Konomos DK, Gravanis I, Dewey SL, Aguzzi A, Heppner FL, Tsirka SE. Microglial ablation and lipopolysaccharide preconditioning affects pilocarpine-induced seizures in mice Neurobiology of Disease. 39: 85-97. PMID 20382223 DOI: 10.1016/J.Nbd.2010.04.001  0.499
2010 Peters O, Prokop S, Heppner F, Heuser I, Schipke CG. P3-167: Determination of long-term stability of A-beta species in human cerebrospinal fluid using different methods Alzheimer's & Dementia. 6: S498-S498. DOI: 10.1016/J.Jalz.2010.05.1665  0.596
2009 Grathwohl SA, Kälin RE, Bolmont T, Prokop S, Winkelmann G, Kaeser SA, Odenthal J, Radde R, Eldh T, Gandy S, Aguzzi A, Staufenbiel M, Mathews PM, Wolburg H, Heppner FL, et al. Formation and maintenance of Alzheimer's disease beta-amyloid plaques in the absence of microglia. Nature Neuroscience. 12: 1361-3. PMID 19838177 DOI: 10.1515/Nf-2010-0107  0.752
2009 Aslund A, Sigurdson CJ, Klingstedt T, Grathwohl S, Bolmont T, Dickstein DL, Glimsdal E, Prokop S, Lindgren M, Konradsson P, Holtzman DM, Hof PR, Heppner FL, Gandy S, Jucker M, et al. Novel pentameric thiophene derivatives for in vitro and in vivo optical imaging of a plethora of protein aggregates in cerebral amyloidoses. Acs Chemical Biology. 4: 673-84. PMID 19624097 DOI: 10.1021/Cb900112V  0.739
2008 Steele AD, Hutter G, Jackson WS, Heppner FL, Borkowski AW, King OD, Raymond GJ, Aguzzi A, Lindquist S. Heat shock factor 1 regulates lifespan as distinct from disease onset in prion disease. Proceedings of the National Academy of Sciences of the United States of America. 105: 13626-31. PMID 18757733 DOI: 10.1073/Pnas.0806319105  0.585
2008 Falsig J, Julius C, Margalith I, Schwarz P, Heppner FL, Aguzzi A. A versatile prion replication assay in organotypic brain slices. Nature Neuroscience. 11: 109-17. PMID 18066056 DOI: 10.1038/Nn2028  0.559
2007 Aguzzi A, Heppner FL, Westner IM, Glatzel M. Prion diseases Neurobiology of Disease. 473-483. DOI: 10.1016/B978-012088592-3/50044-X  0.564
2006 Priller J, Prinz M, Heikenwalder M, Zeller N, Schwarz P, Heppner FL, Aguzzi A. Early and rapid engraftment of bone marrow-derived microglia in scrapie. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 11753-62. PMID 17093096 DOI: 10.1523/Jneurosci.2275-06.2006  0.573
2005 Donofrio G, Heppner FL, Polymenidou M, Musahl C, Aguzzi A. Paracrine inhibition of prion propagation by anti-PrP single-chain Fv miniantibodies. Journal of Virology. 79: 8330-8. PMID 15956578 DOI: 10.1128/Jvi.79.13.8330-8338.2005  0.556
2005 Nikles D, Bach P, Boller K, Merten CA, Montrasio F, Heppner FL, Aguzzi A, Cichutek K, Kalinke U, Buchholz CJ. Circumventing tolerance to the prion protein (PrP): vaccination with PrP-displaying retrovirus particles induces humoral immune responses against the native form of cellular PrP. Journal of Virology. 79: 4033-42. PMID 15767405 DOI: 10.1128/Jvi.79.7.4033-4042.2005  0.561
2005 Heppner FL, Greter M, Marino D, Falsig J, Raivich G, Hövelmeyer N, Waisman A, Rülicke T, Prinz M, Priller J, Becher B, Aguzzi A. Experimental autoimmune encephalomyelitis repressed by microglial paralysis. Nature Medicine. 11: 146-52. PMID 15665833 DOI: 10.1038/Nm1177  0.578
2005 Heppner FL, Greter M, Marino D, Falsig J, Raivich G, Hövelmeyer N, Waisman A, Rülicke T, Prinz M, Priller J, Becher B, Aguzzi A. Erratum: CORRIGENDUM: Experimental autoimmune encephalomyelitis repressed by microglial paralysis Nature Medicine. 11: 455-455. DOI: 10.1038/Nm0405-455  0.486
2004 Heppner FL, Aguzzi A. Recent developments in prion immunotherapy. Current Opinion in Immunology. 16: 594-8. PMID 15342005 DOI: 10.1016/J.Coi.2004.07.008  0.567
2004 Polymenidou M, Heppner FL, Pellicioli EC, Urich E, Miele G, Braun N, Wopfner F, Schätzl HM, Becher B, Aguzzi A. Humoral immune response to native eukaryotic prion protein correlates with anti-prion protection. Proceedings of the National Academy of Sciences of the United States of America. 101: 14670-6. PMID 15292505 DOI: 10.1073/Pnas.0404772101  0.575
2004 Gandy S, DeMattos RB, Lemere CA, Heppner FL, Leverone J, Aguzzi A, Ershler WB, Dai J, Fraser P, Hyslop PS, Holtzman DM, Walker LC, Keller ET. Alzheimer A beta vaccination of rhesus monkeys (Macaca mulatta). Alzheimer Disease and Associated Disorders. 18: 44-6. PMID 15195463 DOI: 10.1097/00002093-200401000-00009  0.535
2004 Heikenwalder M, Prinz M, Heppner FL, Aguzzi A. Current concepts and controversies in prion immunopathology. Journal of Molecular Neuroscience : Mn. 23: 3-12. PMID 15126687 DOI: 10.1385/Jmn:23:1-2:003  0.548
2004 Gandy S, DeMattos RB, Lemere CA, Heppner FL, Leverone J, Aguzzi A, Ershler WB, Dai J, Fraser P, St George Hyslop P, Holtzman DM, Walker LC, Keller ET. Alzheimer's Abeta vaccination of rhesus monkeys (Macaca mulatta). Mechanisms of Ageing and Development. 125: 149-51. PMID 15037022 DOI: 10.1016/J.Mad.2003.12.002  0.56
2004 Genoud N, Behrens A, Miele G, Robay D, Heppner FL, Freigang S, Aguzzi A. Disruption of Doppel prevents neurodegeneration in mice with extensive Prnp deletions. Proceedings of the National Academy of Sciences of the United States of America. 101: 4198-203. PMID 15007175 DOI: 10.1073/Pnas.0400131101  0.541
2003 Prinz M, Heikenwalder M, Junt T, Schwarz P, Glatzel M, Heppner FL, Fu YX, Lipp M, Aguzzi A. Positioning of follicular dendritic cells within the spleen controls prion neuroinvasion. Nature. 425: 957-62. PMID 14562059 DOI: 10.1038/Nature02072  0.558
2003 Aguzzi A, Heppner FL, Heikenwalder M, Prinz M, Mertz K, Seeger H, Glatzel M. Immune system and peripheral nerves in propagation of prions to CNS. British Medical Bulletin. 66: 141-59. PMID 14522856 DOI: 10.1093/Bmb/66.1.141  0.566
2003 Hutter G, Heppner FL, Aguzzi A. No superoxide dismutase activity of cellular prion protein in vivo. Biological Chemistry. 384: 1279-85. PMID 14515989 DOI: 10.1515/Bc.2003.142  0.572
2003 Prinz M, Huber G, Macpherson AJ, Heppner FL, Glatzel M, Eugster HP, Wagner N, Aguzzi A. Oral prion infection requires normal numbers of Peyer's patches but not of enteric lymphocytes. The American Journal of Pathology. 162: 1103-11. PMID 12651603 DOI: 10.1016/S0002-9440(10)63907-7  0.556
2002 Behrens A, Genoud N, Naumann H, Rülicke T, Janett F, Heppner FL, Ledermann B, Aguzzi A. Absence of the prion protein homologue Doppel causes male sterility. The Embo Journal. 21: 3652-8. PMID 12110578 DOI: 10.1093/Emboj/Cdf386  0.548
2002 Heppner FL, Arrighi I, Kalinke U, Aguzzi A. Immunity against prions? Trends in Molecular Medicine. 7: 477-9. PMID 11689311 DOI: 10.1016/S1471-4914(01)02182-7  0.567
2001 Aguzzi A, Glatzel M, Montrasio F, Prinz M, Heppner FL. Interventional strategies against prion diseases. Nature Reviews. Neuroscience. 2: 745-9. PMID 11584312 DOI: 10.1038/35094590  0.532
2001 Heppner FL, Musahl C, Arrighi I, Klein MA, Rülicke T, Oesch B, Zinkernagel RM, Kalinke U, Aguzzi A. Prevention of scrapie pathogenesis by transgenic expression of anti-prion protein antibodies. Science (New York, N.Y.). 294: 178-82. PMID 11546838 DOI: 10.1126/Science.1063093  0.592
2001 Heppner FL, Prinz M, Aguzzi A. Pathogenesis of prion diseases: possible implications of microglial cells. Progress in Brain Research. 132: 737-50. PMID 11545032 DOI: 10.1016/S0079-6123(01)32114-3  0.586
2001 Heppner FL, Christ AD, Klein MA, Prinz M, Fried M, Kraenhenbuhl JP, Aguzzi A. Transepithelial prion transport by M cells [1] Nature Medicine. 7: 976-977. PMID 11533681 DOI: 10.1038/Nm0901-976  0.486
2001 Glatzel M, Heppner FL, Albers KM, Aguzzi A. Sympathetic innervation of lymphoreticular organs is rate limiting for prion neuroinvasion. Neuron. 31: 25-34. PMID 11498048 DOI: 10.1016/S0896-6273(01)00331-2  0.525
2001 Aguzzi A, Brandner S, Fischer MB, Furukawa H, Glatzel M, Hawkins C, Heppner FL, Montrasio F, Navarro B, Parizek P, Pekarik V, Prinz M, Raeber AJ, Röckl C, Klein MA. Spongiform encephalopathies: insights from transgenic models. Advances in Virus Research. 56: 313-52. PMID 11450305 DOI: 10.1016/S0065-3527(01)56032-7  0.592
2000 Banati RB, Newcombe J, Gunn RN, Cagnin A, Turkheimer F, Heppner F, Price G, Wegner F, Giovannoni G, Miller DH, Perkin GD, Smith T, Hewson AK, Bydder G, Kreutzberg GW, et al. The peripheral benzodiazepine binding site in the brain in multiple sclerosis: quantitative in vivo imaging of microglia as a measure of disease activity. Brain : a Journal of Neurology. 123: 2321-37. PMID 11050032 DOI: 10.1093/Brain/123.11.2321  0.316
Low-probability matches (unlikely to be authored by this person)
2008 Jucker M, Heppner FL. Cerebral and peripheral amyloid phagocytes--an old liaison with a new twist. Neuron. 59: 8-10. PMID 18614025 DOI: 10.1016/j.neuron.2008.06.014  0.288
2015 Heppner FL, Ransohoff RM, Becher B. Immune attack: the role of inflammation in Alzheimer disease. Nature Reviews. Neuroscience. 16: 358-72. PMID 25991443 DOI: 10.1038/nrn3880  0.284
2011 Wenzl E, Regehly M, Guse K, Röhn G, Goldbrunner R, Hernáiz-Driever P, Thomale UW, Schüller U, Heppner F, Koch A. Abstract 3452: Molecular genetic analysis of the WTX gene in medulloblastoma Cancer Research. 71: 3452-3452. DOI: 10.1158/1538-7445.Am2011-3452  0.282
2018 Mrdjen D, Pavlovic A, Hartmann FJ, Schreiner B, Utz SG, Leung BP, Lelios I, Heppner FL, Kipnis J, Merkler D, Greter M, Becher B. High-Dimensional Single-Cell Mapping of Central Nervous System Immune Cells Reveals Distinct Myeloid Subsets in Health, Aging, and Disease. Immunity. PMID 29426702 DOI: 10.1016/J.Immuni.2018.01.011  0.266
2005 Gandy S, Heppner FL. Alzheimer's amyloid immunotherapy: quo vadis? The Lancet. Neurology. 4: 452-3. PMID 16033686 DOI: 10.1016/S1474-4422(05)70124-1  0.254
2012 Walter J, Handel LL, Brodhun M, van Rossum D, Hanisch UK, Liebmann L, Heppner F, Goldbrunner R, Koch A, Kuhn SA. Expression of coagulation factors and their receptors in tumor tissue and coagulation factor upregulation in peripheral blood of patients with cerebral carcinoma metastases. Journal of Cancer Research and Clinical Oncology. 138: 141-51. PMID 22065054 DOI: 10.1007/S00432-011-1078-X  0.253
2023 Kaul PD, Ehret F, Roohani S, Jendrach PM, Buthut M, Acker G, Anwar M, Zips D, Heppner F, Prüss H. Radiotherapy in Alzheimer's Disease: A Systematic Review. International Journal of Radiation Oncology, Biology, Physics. PMID 38042449 DOI: 10.1016/j.ijrobp.2023.11.044  0.248
2019 Houtman J, Freitag K, Gimber N, Schmoranzer J, Heppner FL, Jendrach M. Beclin1-driven autophagy modulates the inflammatory response of microglia via NLRP3. The Embo Journal. PMID 30617086 DOI: 10.15252/Embj.201899430  0.245
2022 Shibuya Y, Kumar KK, Mader MM, Yoo Y, Ayala LA, Zhou M, Mohr MA, Neumayer G, Kumar I, Yamamoto R, Marcoux P, Liou B, Bennett FC, Nakauchi H, Sun Y, ... ... Heppner FL, et al. Treatment of a genetic brain disease by CNS-wide microglia replacement. Science Translational Medicine. 14: eabl9945. PMID 35294256 DOI: 10.1126/scitranslmed.abl9945  0.244
2015 Kreher S, Jöhrens K, Strehlow F, Martus P, Borowiec K, Radke J, Heppner F, Roth P, Thiel E, Pietsch T, Weller M, Korfel A. Prognostic impact of B-cell lymphoma 6 in primary CNS lymphoma. Neuro-Oncology. 17: 1016-21. PMID 25817328 DOI: 10.1093/Neuonc/Nov046  0.243
2016 Atangana E, Schneider UC, Blecharz K, Magrini S, Wagner J, Nieminen-Kelhä M, Kremenetskaia I, Heppner FL, Engelhardt B, Vajkoczy P. Intravascular Inflammation Triggers Intracerebral Activated Microglia and Contributes to Secondary Brain Injury After Experimental Subarachnoid Hemorrhage (eSAH). Translational Stroke Research. PMID 27477569 DOI: 10.1007/S12975-016-0485-3  0.237
2005 Gandy S, Heppner FL. Breaking up (amyloid) is hard to do. Plos Medicine. 2: e417. PMID 16363913 DOI: 10.1371/journal.pmed.0020417  0.232
2012 Pantelyushin S, Haak S, Ingold B, Kulig P, Heppner FL, Navarini AA, Becher B. Rorγt+ innate lymphocytes and γδ T cells initiate psoriasiform plaque formation in mice. The Journal of Clinical Investigation. 122: 2252-6. PMID 22546855 DOI: 10.1172/JCI61862  0.232
2012 Bahra M, Kamphues C, Boas-Knoop S, Lippert S, Esendik U, Schüller U, Hartmann W, Waha A, Neuhaus P, Heppner F, Pietsch T, Koch A. Combination of Hedgehog signaling blockage and chemotherapy leads to tumor reduction in pancreatic adenocarcinomas Pancreas. 41: 222-229. PMID 22076568 DOI: 10.1097/Mpa.0B013E31822896Dd  0.231
2022 Lang AL, Eulalio T, Fox E, Yakabi K, Bukhari SA, Kawas CH, Corrada MM, Montgomery SB, Heppner FL, Capper D, Nachun D, Montine TJ. Methylation differences in Alzheimer's disease neuropathologic change in the aged human brain. Acta Neuropathologica Communications. 10: 174. PMID 36447297 DOI: 10.1186/s40478-022-01470-0  0.229
2009 Czabanka M, Vinci M, Heppner F, Ullrich A, Vajkoczy P. Effects of sunitinib on tumor hemodynamics and delivery of chemotherapy. International Journal of Cancer. 124: 1293-300. PMID 19101989 DOI: 10.1002/Ijc.24019  0.229
2004 Heppner FL, Gandy S, McLaurin J. Current concepts and future prospects for Alzheimer disease vaccines. Alzheimer Disease and Associated Disorders. 18: 38-43. PMID 15195462  0.228
2018 Capper D, Jones DTW, Sill M, Hovestadt V, Schrimpf D, Sturm D, Koelsche C, Sahm F, Chavez L, Reuss DE, Kratz A, Wefers AK, Huang K, Pajtler KW, Schweizer L, ... ... Heppner F, et al. DNA methylation-based classification of central nervous system tumours. Nature. PMID 29539639 DOI: 10.1038/Nature26000  0.228
2016 Heppner FL. S5-01-03: Therapeutic Opportunities for the Modulation of Myeloid Cells for the Treatment of Alzheimer's Disease Alzheimer's & Dementia. 12: P366-P366. DOI: 10.1016/j.jalz.2016.06.681  0.225
2015 Pehl D, Preusse C, Rinnenthal J, Schneider U, Heppner F, Allenbach Y, Benveniste O, Goebel H, Stenzel W. Perifascicular pathology in eosinophilic fasciitis with muscle involvement Neuromuscular Disorders. 25. DOI: 10.1016/J.Nmd.2015.06.440  0.223
2009 Synowitz M, Markovic D, Chirasani S, Vinnakota K, Holmbeck K, Lehnardt S, van Rooijen N, Heppner F, Kaminska B, Kettenmann H, Glass R. Glioma Induce and Exploit Microglial Membrane Type 1 Metalloprotease Expression for Tumor Expansion: 974. Neurosurgery. 65: 425. PMID 28173380 DOI: 10.1227/01.Neu.0000358745.47658.D3  0.222
2020 Jank P, Gehlhaar C, Bianca L, Caterina F, Andreas S, Karn T, Marmé F, Sinn HP, van Mackelenbergh M, Sinn B, Zahm DM, Ingold-Heppner B, Schem C, Stickeler E, Fasching PA, ... ... Heppner F, et al. MGMT promoter methylation in triple negative breast cancer of the GeparSixto trial. Plos One. 15: e0238021. PMID 32841306 DOI: 10.1371/Journal.Pone.0238021  0.221
2005 Buch T, Heppner FL, Tertilt C, Heinen TJ, Kremer M, Wunderlich FT, Jung S, Waisman A. A Cre-inducible diphtheria toxin receptor mediates cell lineage ablation after toxin administration. Nature Methods. 2: 419-26. PMID 15908920 DOI: 10.1038/Nmeth762  0.218
2007 Krayenbühl N, Heppner F, Yonekawa Y, Bernays RL. Intrasellar malignant peripheral nerve sheath tumor (MPNST) Acta Neurochirurgica. 149: 201-206. PMID 17195046 DOI: 10.1007/S00701-006-1080-2  0.217
2015 Schneider UC, Davids AM, Brandenburg S, Müller A, Elke A, Magrini S, Atangana E, Turkowski K, Finger T, Gutenberg A, Gehlhaar C, Brück W, Heppner FL, Vajkoczy P. Microglia inflict delayed brain injury after subarachnoid hemorrhage. Acta Neuropathologica. 130: 215-31. PMID 25956409 DOI: 10.1007/s00401-015-1440-1  0.214
2016 Onken J, Torka R, Korsing S, Radke J, Kremenetskaia I, Nieminen M, Bai X, Ullrich A, Heppner F, Vajkoczy P. Inhibiting receptor tyrosine kinase AXL with small molecule inhibitor BMS-777607 reduces glioblastoma growth, migration, and invasion in vitro and in vivo. Oncotarget. PMID 26848524 DOI: 10.18632/Oncotarget.7130  0.213
2009 Heppner F. Introductory biology: let's train lecturers. Science (New York, N.Y.). 325: 1338. PMID 19745132 DOI: 10.1126/Science.325_1338B  0.212
2023 Freitag K, Eede P, Ivanov A, Sterczyk N, Schneeberger S, Borodina T, Sauer S, Beule D, Heppner FL. Diverse but unique astrocytic phenotypes during embryonic stem cell differentiation, culturing and development. Communications Biology. 6: 40. PMID 36639529 DOI: 10.1038/s42003-023-04410-3  0.21
2013 Gandy S, Heppner FL. Microglia as dynamic and essential components of the amyloid hypothesis. Neuron. 78: 575-7. PMID 23719156 DOI: 10.1016/J.Neuron.2013.05.007  0.209
2016 Fontanella C, Gehlhaar C, Denkert C, Schneeweiss A, Heppner B, Koch I, Blohmer J, Jackisch C, Lederer B, Fasching P, Müller V, Untch M, Aprile G, Puglisi F, Nekljudova V, ... Heppner F, et al. Abstract P3-07-55: Predictive value of O6-methylguanine-DNA methyltransferase (MGMT) promoter gene methylation in triple-negative breast cancer patients receiving carboplatin Cancer Research. 76. DOI: 10.1158/1538-7445.Sabcs15-P3-07-55  0.207
2008 Gao Z, Wang J, Thiex R, Rogove AD, Heppner FL, Tsirka SE. Microglial activation and intracerebral hemorrhage Acta Neurochirurgica, Supplementum. 51-53. PMID 19066082 DOI: 10.1007/978-3-211-09469-3_11  0.207
2005 Greter M, Heppner FL, Lemos MP, Odermatt BM, Goebels N, Laufer T, Noelle RJ, Becher B. Dendritic cells permit immune invasion of the CNS in an animal model of multiple sclerosis Nature Medicine. 11: 328-334. PMID 15735653 DOI: 10.1038/Nm1197  0.205
2015 Pehl D, Radke J, Irlbacher K, Heppner F, Goebel H, Stenzel W. Late-onset zebra body myopathy Neuromuscular Disorders. 25: S276. DOI: 10.1016/J.Nmd.2015.06.326  0.205
2012 Lehmann SM, Krüger C, Park B, Derkow K, Rosenberger K, Baumgart J, Trimbuch T, Eom G, Hinz M, Kaul D, Habbel P, Kälin R, Franzoni E, Rybak A, Nguyen D, ... ... Heppner FL, et al. An unconventional role for miRNA: let-7 activates Toll-like receptor 7 and causes neurodegeneration. Nature Neuroscience. 15: 827-35. PMID 22610069 DOI: 10.1038/Nn.3113  0.204
2009 Schreiner B, Heppner FL, Becher B. Modeling multiple sclerosis in laboratory animals Seminars in Immunopathology. 31: 479-495. PMID 19802608 DOI: 10.1007/s00281-009-0181-4  0.201
2011 Calderón-Gómez E, Lampropoulou V, Shen P, Neves P, Roch T, Stervbo U, Rutz S, Kühl AA, Heppner FL, Loddenkemper C, Anderton SM, Kanellopoulos JM, Charneau P, Fillatreau S. Reprogrammed quiescent B cells provide an effective cellular therapy against chronic experimental autoimmune encephalomyelitis. European Journal of Immunology. 41: 1696-708. PMID 21469107 DOI: 10.1002/eji.201041041  0.2
2012 Preuße C, Goebel HH, Held J, Wengert O, Scheibe F, Irlbacher K, Koch A, Heppner FL, Stenzel W. Immune-mediated necrotizing myopathy is characterized by a specific Th1-M1 polarized immune profile. The American Journal of Pathology. 181: 2161-71. PMID 23058368 DOI: 10.1016/J.Ajpath.2012.08.033  0.193
2023 Andreadou M, Ingelfinger F, De Feo D, Cramer TLM, Tuzlak S, Friebel E, Schreiner B, Eede P, Schneeberger S, Geesdorf M, Ridder F, Welsh CA, Power L, Kirschenbaum D, Tyagarajan SK, ... ... Heppner FL, et al. IL-12 sensing in neurons induces neuroprotective CNS tissue adaptation and attenuates neuroinflammation in mice. Nature Neuroscience. 26: 1701-1712. PMID 37749256 DOI: 10.1038/s41593-023-01435-z  0.189
2012 Vinet J, Weering HR, Heinrich A, Kälin RE, Wegner A, Brouwer N, Heppner FL, Rooijen Nv, Boddeke HW, Biber K. Neuroprotective function for ramified microglia in hippocampal excitotoxicity. Journal of Neuroinflammation. 9: 27. PMID 22293457 DOI: 10.1186/1742-2094-9-27  0.185
2020 Dembny P, Newman AG, Singh M, Hinz M, Szczepek M, Krüger C, Adalbert R, Dzaye O, Trimbuch T, Wallach T, Kleinau G, Derkow K, Richard BC, Schipke C, Scheidereit C, ... ... Heppner FL, et al. Human endogenous retrovirus HERV-K(HML-2) RNA causes neurodegeneration through Toll-like receptors. Jci Insight. 5. PMID 32271161 DOI: 10.1172/jci.insight.131093  0.182
1998 Hailer NP, Heppner FL, Haas D, Nitsch R. Astrocytic factors deactivate antigen presenting cells that invade the central nervous system. Brain Pathology (Zurich, Switzerland). 8: 459-74. PMID 9669697 DOI: 10.1111/j.1750-3639.1998.tb00168.x  0.181
1997 Hailer NP, Heppner FL, Haas D, Nitsch R. Fluorescent dye prelabelled microglial cells migrate into organotypic hippocampal slice cultures and ramify. The European Journal of Neuroscience. 9: 863-6. PMID 9153594 DOI: 10.1111/j.1460-9568.1997.tb01436.x  0.181
2023 Mothes R, Pascual-Reguant A, Koehler R, Liebeskind J, Liebheit A, Bauherr S, Philipsen L, Dittmayer C, Laue M, von Manitius R, Elezkurtaj S, Durek P, Heinrich F, Heinz GA, Guerra GM, ... ... Heppner FL, et al. Distinct tissue niches direct lung immunopathology via CCL18 and CCL21 in severe COVID-19. Nature Communications. 14: 791. PMID 36774347 DOI: 10.1038/s41467-023-36333-2  0.178
2023 Meinhardt J, Streit S, Dittmayer C, Manitius RV, Radbruch H, Heppner FL. The neurobiology of SARS-CoV-2 infection. Nature Reviews. Neuroscience. 25: 30-42. PMID 38049610 DOI: 10.1038/s41583-023-00769-8  0.177
2022 Dimasuay KG, Schaunaman N, Berg B, Cervantes D, Kruger E, Heppner FL, Ferrington DA, Chu HW. Airway epithelial immunoproteasome subunit LMP7 protects against rhinovirus infection. Scientific Reports. 12: 14507. PMID 36008456 DOI: 10.1038/s41598-022-18807-3  0.175
2008 Gianella S, Schaer DJ, Schwarz U, Kurrer M, Heppner FL, Fehr J, Seebach JD. Retinal microangiopathy and rapidly fatal cerebral edema in a patient with adult-onset Still's disease and concurrent macrophage activation syndrome. American Journal of Hematology. 83: 424-7. PMID 18183612 DOI: 10.1002/ajh.21084  0.171
2013 Held J, Preuße C, Döser A, Richter L, Heppner FL, Stenzel W. Enhanced acute immune response in IL-12p35-/- mice is followed by accelerated distinct repair mechanisms in Staphylococcus aureus-induced murine brain abscess. The Journal of Infectious Diseases. 208: 749-60. PMID 23532102 DOI: 10.1093/infdis/jit126  0.171
2018 Robson JP, Wagner B, Glitzner E, Heppner FL, Steinkellner T, Khan D, Petritsch C, Pollak DD, Sitte HH, Sibilia M. Impaired neural stem cell expansion and hypersensitivity to epileptic seizures in mice lacking the EGFR in the brain. The Febs Journal. PMID 30028091 DOI: 10.1111/Febs.14603  0.169
2018 Mrdjen D, Pavlovic A, Hartmann FJ, Schreiner B, Utz SG, Leung BP, Lelios I, Heppner FL, Kipnis J, Merkler D, Greter M, Becher B. High-Dimensional Single-Cell Mapping of Central Nervous System Immune Cells Reveals Distinct Myeloid Subsets in Health, Aging, and Disease. Immunity. 48: 599. PMID 29562204 DOI: 10.1016/j.immuni.2018.02.014  0.166
2024 Radke J, Meinhardt J, Aschman T, Chua RL, Farztdinov V, Lukassen S, Ten FW, Friebel E, Ishaque N, Franz J, Huhle VH, Mothes R, Peters K, Thomas C, Schneeberger S, ... ... Heppner FL, et al. Proteomic and transcriptomic profiling of brainstem, cerebellum and olfactory tissues in early- and late-phase COVID-19. Nature Neuroscience. PMID 38366144 DOI: 10.1038/s41593-024-01573-y  0.165
2010 Sutter R, Shakhova O, Bhagat H, Behesti H, Sutter C, Penkar S, Santuccione A, Bernays R, Heppner FL, Schüller U, Grotzer M, Moch H, Schraml P, Marino S. Cerebellar stem cells act as medulloblastoma-initiating cells in a mouse model and a neural stem cell signature characterizes a subset of human medulloblastomas. Oncogene. 29: 1845-56. PMID 20062081 DOI: 10.1038/onc.2009.472  0.164
2010 Fulop T, Larbi A, Tsvetkova K, Allard N, Dernhovassian E, Frost E, Pawelec G, Mues M, Direnberger S, Mank M, Griesbeck O, Odoardi F, Flügel A, Krishnamoorthy G, Wekerle H, ... ... Heppner F, et al. Neuroimmunology (WS-012) Chairpersons: Takashi Yamamura, Britta Engelhardt International Immunology. 22. DOI: 10.1093/Intimm/Dxq167  0.164
2023 Reinhold D, Farztdinov V, Yan Y, Meisel C, Sadlowski H, Kühn J, Perschel FH, Endres M, Düzel E, Vielhaber S, Guttek K, Goihl A, Venø M, Teegen B, Stöcker W, ... ... Heppner F, et al. The brain reacting to COVID-19: analysis of the cerebrospinal fluid proteome, RNA and inflammation. Journal of Neuroinflammation. 20: 30. PMID 36759861 DOI: 10.1186/s12974-023-02711-2  0.162
2012 Locatelli G, Wörtge S, Buch T, Ingold B, Frommer F, Sobottka B, Krüger M, Karram K, Bühlmann C, Bechmann I, Heppner FL, Waisman A, Becher B. Primary oligodendrocyte death does not elicit anti-CNS immunity. Nature Neuroscience. 15: 543-50. PMID 22366759 DOI: 10.1038/nn.3062  0.162
2009 Kuehnle K, Ledesma MD, Kalvodova L, Smith AE, Crameri A, Skaanes-Brunner F, Thelen KM, Kulic L, Lütjohann D, Heppner FL, Nitsch RM, Mohajeri MH. Age-dependent increase in desmosterol restores DRM formation and membrane-related functions in cholesterol-free DHCR24-/- mice. Neurochemical Research. 34: 1167-82. PMID 19115107 DOI: 10.1007/s11064-008-9893-4  0.157
2009 Haak S, Croxford AL, Kreymborg K, Heppner FL, Pouly S, Becher B, Waisman A. IL-17A and IL-17F do not contribute vitally to autoimmune neuro-inflammation in mice. The Journal of Clinical Investigation. 119: 61-9. PMID 19075395 DOI: 10.1172/JCI35997  0.156
2009 Stenzel W, Müller U, Köhler G, Heppner FL, Blessing M, McKenzie AN, Brombacher F, Alber G. IL-4/IL-13-dependent alternative activation of macrophages but not microglial cells is associated with uncontrolled cerebral cryptococcosis. The American Journal of Pathology. 174: 486-96. PMID 19147811 DOI: 10.2353/ajpath.2009.080598  0.155
2022 Radke J, Schumann E, Onken J, Koll R, Acker G, Bodnar B, Senger C, Tierling S, Möbs M, Vajkoczy P, Vidal A, Högler S, Kodajova P, Westphal D, Meier F, ... Heppner F, et al. Decoding molecular programs in melanoma brain metastases. Nature Communications. 13: 7304. PMID 36435874 DOI: 10.1038/s41467-022-34899-x  0.153
2015 Kälin S, Heppner FL, Bechmann I, Prinz M, Tschöp MH, Yi CX. Hypothalamic innate immune reaction in obesity. Nature Reviews. Endocrinology. 11: 339-51. PMID 25824676 DOI: 10.1038/nrendo.2015.48  0.15
2006 Ohgaki H, Kita D, Favereaux A, Huang H, Homma T, Dessen P, Weiss WA, Kleihues P, Heppner FL. Brain tumors in S100beta-v-erbB transgenic rats. Journal of Neuropathology and Experimental Neurology. 65: 1111-7. PMID 17146284 DOI: 10.1097/01.Jnen.0000248544.28423.48  0.149
2013 Stenzel W, Preusse C, Pehl D, Heppner F, Weis J, Claes K, Rushing E, Kana V, Benveniste O, Goebel H. O.16 Morphological and molecular heterogeneity in autoimmune necrotizing myopathies Neuromuscular Disorders. 23: 849. DOI: 10.1016/J.Nmd.2013.06.726  0.148
2021 Gassen NC, Papies J, Bajaj T, Emanuel J, Dethloff F, Chua RL, Trimpert J, Heinemann N, Niemeyer C, Weege F, Hönzke K, Aschman T, Heinz DE, Weckmann K, Ebert T, ... ... Heppner FL, et al. SARS-CoV-2-mediated dysregulation of metabolism and autophagy uncovers host-targeting antivirals. Nature Communications. 12: 3818. PMID 34155207 DOI: 10.1038/s41467-021-24007-w  0.148
2012 Bradtmöller M, Hartmann C, Zietsch J, Jäschke S, Mautner VF, Kurtz A, Park SJ, Baier M, Harder A, Reuss D, von Deimling A, Heppner FL, Holtkamp N. Impaired Pten expression in human malignant peripheral nerve sheath tumours. Plos One. 7: e47595. PMID 23139750 DOI: 10.1371/journal.pone.0047595  0.146
2017 Amulic B, Knackstedt SL, Abu Abed U, Deigendesch N, Harbort CJ, Caffrey BE, Brinkmann V, Heppner FL, Hinds PW, Zychlinsky A. Cell-Cycle Proteins Control Production of Neutrophil Extracellular Traps. Developmental Cell. PMID 29103955 DOI: 10.1016/J.Devcel.2017.10.013  0.144
2010 Grathwohl SA, Varvel NH, Baumann F, Heppner FL, Jucker M. O4-05-07: The role of immune cells in mouse models of cerebral amyloidosis Alzheimer's & Dementia. 6: S158-S158. DOI: 10.1016/J.Jalz.2010.05.494  0.144
2007 Kreymborg K, Etzensperger R, Dumoutier L, Haak S, Rebollo A, Buch T, Heppner FL, Renauld JC, Becher B. IL-22 is expressed by Th17 cells in an IL-23-dependent fashion, but not required for the development of autoimmune encephalomyelitis. Journal of Immunology (Baltimore, Md. : 1950). 179: 8098-104. PMID 18056351  0.143
2022 Aschman T, Mothes R, Heppner FL, Radbruch H. What SARS-CoV-2 does to our brains. Immunity. PMID 35777361 DOI: 10.1016/j.immuni.2022.06.013  0.141
2022 Jonigk D, Werlein C, Acker T, Aepfelbacher M, Amann KU, Baretton G, Barth P, Bohle RM, Büttner A, Büttner R, Dettmeyer R, Eichhorn P, Elezkurtaj S, Esposito I, Evert K, ... ... Heppner FL, et al. Organ manifestations of COVID-19: what have we learned so far (not only) from autopsies? Virchows Archiv : An International Journal of Pathology. PMID 35364700 DOI: 10.1007/s00428-022-03319-2  0.139
2022 Pietzner M, Chua RL, Wheeler E, Jechow K, Willett JDS, Radbruch H, Trump S, Heidecker B, Zeberg H, Heppner FL, Eils R, Mall MA, Richards JB, Sander LE, Lehmann I, et al. ELF5 is a potential respiratory epithelial cell-specific risk gene for severe COVID-19. Nature Communications. 13: 4484. PMID 35970849 DOI: 10.1038/s41467-022-31999-6  0.138
2022 Radke J, Ishaque N, Koll R, Gu Z, Schumann E, Sieverling L, Uhrig S, Hübschmann D, Toprak UH, López C, Hostench XP, Borgoni S, Juraeva D, Pritsch F, Paramasivam N, ... ... Heppner FL, et al. The genomic and transcriptional landscape of primary central nervous system lymphoma. Nature Communications. 13: 2558. PMID 35538064 DOI: 10.1038/s41467-022-30050-y  0.137
2018 Mpambani F, Åslund AK, Lerouge F, Nyström S, Reitan N, Huuse EM, Widerøe M, Chaput F, Monnereau C, Andraud C, Lecouvey M, Handrick S, Prokop S, Heppner FL, Nilsson P, et al. Two-Photon Fluorescence and Magnetic Resonance Specific Imaging of Aβ Amyloid Using Hybrid Nano-GdF3 Contrast Media Acs Applied Bio Materials. 1: 462-472. DOI: 10.1021/ACSABM.8B00191  0.137
2021 Schweizer L, Thierfelder F, Thomas C, Soschinski P, Kim HY, Jödicke R, Woltering N, Förster A, Teichmann D, Siewert C, Klein K, Schmid S, Nunninger M, Thomale UW, Onken J, ... ... Heppner FL, et al. Molecular characterisation of sporadic endolymphatic sac tumours and comparison to von Hippel-Lindau disease-related tumours. Neuropathology and Applied Neurobiology. PMID 34091929 DOI: 10.1111/nan.12741  0.132
2022 Schweizer L, Seegerer P, Kim HY, Saitenmacher R, Muench A, Barnick L, Osterloh A, Dittmayer C, Jödicke R, Pehl D, Reinhardt A, Ruprecht K, Stenzel W, Wefers AK, Harter PN, ... ... Heppner FL, et al. Analysing Cerebrospinal Fluid with Explainable Deep Learning: from Diagnostics to Insights. Neuropathology and Applied Neurobiology. e12866. PMID 36519297 DOI: 10.1111/nan.12866  0.131
1998 Heppner FL, Roth K, Nitsch R, Hailer NP. Vitamin E induces ramification and downregulation of adhesion molecules in cultured microglial cells. Glia. 22: 180-8. PMID 9537838 DOI: 10.1002/(SICI)1098-1136(199802)22:2<180::AID-GLIA9>3.0.CO;2-B  0.129
2020 Meinhardt J, Radke J, Dittmayer C, Franz J, Thomas C, Mothes R, Laue M, Schneider J, Brünink S, Greuel S, Lehmann M, Hassan O, Aschman T, Schumann E, Chua RL, ... ... Heppner FL, et al. Olfactory transmucosal SARS-CoV-2 invasion as a port of central nervous system entry in individuals with COVID-19. Nature Neuroscience. PMID 33257876 DOI: 10.1038/s41593-020-00758-5  0.129
2015 Hu F, a Dzaye OD, Hahn A, Yu Y, Scavetta RJ, Dittmar G, Kaczmarek AK, Dunning KR, Ricciardelli C, Rinnenthal JL, Heppner FL, Lehnardt S, Synowitz M, Wolf SA, Kettenmann H. Glioma-derived versican promotes tumor expansion via glioma-associated microglial/macrophages Toll-like receptor 2 signaling. Neuro-Oncology. 17: 200-10. PMID 25452390 DOI: 10.1093/Neuonc/Nou324  0.127
2014 Radke J, Pehl D, Aronica E, Schonenberg-Meinema D, Schneider U, Heppner FL, de Visser M, Goebel HH, Stenzel W. The lymphoid follicle variant of dermatomyositis. Neurology® Neuroimmunology & Neuroinflammation. 1: e19. PMID 25340071 DOI: 10.1212/NXI.0000000000000019  0.126
2018 Papageorgiou IE, Valous NA, Lahrmann B, Janova H, Klaft ZJ, Koch A, Schneider UC, Vajkoczy P, Heppner FL, Grabe N, Halama N, Heinemann U, Kann O. Astrocytic glutamine synthetase is expressed in the neuronal somatic layers and down-regulated proportionally to neuronal loss in the human epileptic hippocampus. Glia. PMID 29350438 DOI: 10.1002/Glia.23292  0.124
2011 Wengert O, Meisel A, Kress W, Dekomien G, Angstwurm K, Heppner FL, Goebel HH, Stenzel W. Progressive external ophthalmoplegia as initial manifestation of sporadic late-onset nemaline myopathy. Journal of Neurology. 258: 915-7. PMID 21072530 DOI: 10.1007/s00415-010-5819-6  0.124
2022 Hönzke K, Obermayer B, Mache C, Fathykova D, Kessler M, Dökel S, Wyler E, Baumgardt M, Löwa A, Hoffmann K, Graff P, Schulze J, Mieth M, Hellwig K, Demir Z, ... ... Heppner F, et al. Human lungs show limited permissiveness for SARS-CoV-2 due to scarce ACE2 levels but virus-induced expansion of inflammatory macrophages. The European Respiratory Journal. PMID 35728978 DOI: 10.1183/13993003.02725-2021  0.123
2015 Preusse C, Goebel HH, Pehl D, Rinnenthal JL, Kley RA, Allenbach Y, Heppner FL, Vorgerd M, Authier FJ, Gherardi R, Stenzel W. Th2-M2 immunity in lesions of muscular sarcoidosis and macrophagic myofasciitis. Neuropathology and Applied Neurobiology. PMID 25711697 DOI: 10.1111/nan.12231  0.122
2024 Sachs W, Blume L, Loreth D, Schebsdat L, Hatje F, Koehler S, Wedekind U, Sachs M, Zieliniski S, Brand J, Conze C, Florea BI, Heppner F, Krüger E, Rinschen MM, et al. The proteasome modulates endocytosis specifically in glomerular cells to promote kidney filtration. Nature Communications. 15: 1897. PMID 38429282 DOI: 10.1038/s41467-024-46273-0  0.12
2007 Kälin RE, Kretz MP, Meyer AM, Kispert A, Heppner FL, Brändli AW. Paracrine and autocrine mechanisms of apelin signaling govern embryonic and tumor angiogenesis. Developmental Biology. 305: 599-614. PMID 17412318 DOI: 10.1016/j.ydbio.2007.03.004  0.12
2014 Rinnenthal JL, Goebel HH, Preuße C, Lebenheim L, Schumann M, Moos V, Schneider T, Heppner FL, Stenzel W. Inflammatory myopathy with abundant macrophages (IMAM): the immunology revisited. Neuromuscular Disorders : Nmd. 24: 151-5. PMID 24314585 DOI: 10.1016/j.nmd.2013.11.004  0.118
2019 Schwabenland M, Mossad O, Peres AG, Kessler F, Maron FJM, Harsan LA, Bienert T, von Elverfeldt D, Knobeloch KP, Staszewski O, Heppner FL, Meuwissen MEC, Mancini GMS, Prinz M, Blank T. Loss of USP18 in microglia induces white matter pathology. Acta Neuropathologica Communications. 7: 106. PMID 31272490 DOI: 10.1186/s40478-019-0757-8  0.118
2007 Eckert A, Kloor M, Giersch A, Ahmadi R, Herold-Mende C, Hampl JA, Heppner FL, Zoubaa S, Holinski-Feder E, Pietsch T, Wiestler OD, von Knebel Doeberitz M, Roth W, Gebert J. Microsatellite instability in pediatric and adult high-grade gliomas. Brain Pathology (Zurich, Switzerland). 17: 146-50. PMID 17388945 DOI: 10.1111/j.1750-3639.2007.00049.x  0.118
2009 Markovic DS, Vinnakota K, Chirasani S, Synowitz M, Raguet H, Stock K, Sliwa M, Lehmann S, Kälin R, van Rooijen N, Holmbeck K, Heppner FL, Kiwit J, Matyash V, Lehnardt S, et al. Gliomas induce and exploit microglial MT1-MMP expression for tumor expansion. Proceedings of the National Academy of Sciences of the United States of America. 106: 12530-5. PMID 19617536 DOI: 10.1073/Pnas.0804273106  0.117
2008 Kuehnle K, Crameri A, Kälin RE, Luciani P, Benvenuti S, Peri A, Ratti F, Rodolfo M, Kulic L, Heppner FL, Nitsch RM, Mohajeri MH. Prosurvival effect of DHCR24/Seladin-1 in acute and chronic responses to oxidative stress. Molecular and Cellular Biology. 28: 539-50. PMID 17984220 DOI: 10.1128/MCB.00584-07  0.114
2020 Frisch A, Kälin S, Monk R, Radke J, Heppner FL, Kälin RE. Apelin Controls Angiogenesis-Dependent Glioblastoma Growth. International Journal of Molecular Sciences. 21. PMID 32545380 DOI: 10.3390/ijms21114179  0.113
2022 Krasemann S, Dittmayer C, von Stillfried S, Meinhardt J, Heinrich F, Hartmann K, Pfefferle S, Thies E, von Manitius R, Aschman TAD, Radke J, Osterloh A, Schmid S, Buhl EM, Ihlow J, ... ... Heppner FL, et al. Assessing and improving the validity of COVID-19 autopsy studies - A multicentre approach to establish essential standards for immunohistochemical and ultrastructural analyses. Ebiomedicine. 83: 104193. PMID 35930888 DOI: 10.1016/j.ebiom.2022.104193  0.112
2024 Rifat A, Ossola B, Bürli RW, Dawson LA, Brice NL, Rowland A, Lizio M, Xu X, Page K, Fidzinski P, Onken J, Holtkamp M, Heppner FL, Geiger JRP, Madry C. Differential contribution of THIK-1 K channels and P2X7 receptors to ATP-mediated neuroinflammation by human microglia. Journal of Neuroinflammation. 21: 58. PMID 38409076 DOI: 10.1186/s12974-024-03042-6  0.112
2004 Horstmann S, Perry A, Reifenberger G, Giangaspero F, Huang H, Hara A, Masuoka J, Rainov NG, Bergmann M, Heppner FL, Brandner S, Chimelli L, Montagna N, Jackson T, Davis DG, et al. Genetic and expression profiles of cerebellar liponeurocytomas. Brain Pathology (Zurich, Switzerland). 14: 281-9. PMID 15446583 DOI: 10.1111/J.1750-3639.2004.Tb00065.X  0.111
2013 Schröder NW, Goebel HH, Brandis A, Ladhoff AM, Heppner FL, Stenzel W. Pipestem capillaries in necrotizing myopathy revisited. Neuromuscular Disorders : Nmd. 23: 66-74. PMID 23102899 DOI: 10.1016/j.nmd.2012.09.001  0.109
1998 Heppner FL, Skutella T, Hailer NP, Haas D, Nitsch R. Activated microglial cells migrate towards sites of excitotoxic neuronal injury inside organotypic hippocampal slice cultures. The European Journal of Neuroscience. 10: 3284-90. PMID 9786222 DOI: 10.1046/j.1460-9568.1998.00379.x  0.109
2021 Wendisch D, Dietrich O, Mari T, von Stillfried S, Ibarra IL, Mittermaier M, Mache C, Chua RL, Knoll R, Timm S, Brumhard S, Krammer T, Zauber H, Hiller AL, Pascual-Reguant A, ... ... Heppner FL, et al. SARS-CoV-2 infection triggers profibrotic macrophage responses and lung fibrosis. Cell. PMID 34914922 DOI: 10.1016/j.cell.2021.11.033  0.106
2011 Zhai H, Heppner FL, Tsirka SE. Microglia/macrophages promote glioma progression Glia. 59: 472-485. PMID 21264953 DOI: 10.1002/Glia.21117  0.102
2004 Huang H, Okamoto Y, Yokoo H, Heppner FL, Vital A, Fevre-Montange M, Jouvet A, Yonekawa Y, Lazaridis EN, Kleihues P, Ohgaki H. Gene expression profiling and subgroup identification of oligodendrogliomas. Oncogene. 23: 6012-22. PMID 15208679 DOI: 10.1038/sj.onc.1207781  0.102
2022 Wasilewski D, Radke J, Xu R, Raspe M, Trelinska-Finger A, Rosenstock T, Poeser P, Schumann E, Lindner J, Heppner F, Kaul D, Suttorp N, Vajkoczy P, Frost N, Onken J. Effectiveness of Immune Checkpoint Inhibition vs Chemotherapy in Combination With Radiation Therapy Among Patients With Non-Small Cell Lung Cancer and Brain Metastasis Undergoing Neurosurgical Resection. Jama Network Open. 5: e229553. PMID 35486401 DOI: 10.1001/jamanetworkopen.2022.9553  0.101
2015 Dietel M, Jöhrens K, Laffert MV, Hummel M, Bläker H, Pfitzner BM, Lehmann A, Denkert C, Darb-Esfahani S, Lenze D, Heppner FL, Koch A, Sers C, Klauschen F, Anagnostopoulos I. A 2015 update on predictive molecular pathology and its role in targeted cancer therapy: a review focussing on clinical relevance. Cancer Gene Therapy. 22: 417-30. PMID 26358176 DOI: 10.1038/cgt.2015.39  0.101
2015 Stenzel W, Preuße C, Allenbach Y, Pehl D, Junckerstorff R, Heppner FL, Nolte K, Aronica E, Kana V, Rushing E, Schneider U, Claeys KG, Benveniste O, Weis J, Goebel HH. Nuclear actin aggregation is a hallmark of anti-synthetase syndrome-induced dysimmune myopathy. Neurology. 84: 1346-54. PMID 25746564 DOI: 10.1212/Wnl.0000000000001422  0.099
2018 Radke J, Koll R, Preuße C, Pehl D, Todorova K, Schönemann C, Allenbach Y, Aronica E, de Visser M, Heppner FL, Weis J, Doostkam S, Maisonobe T, Benveniste O, Goebel HH, et al. Architectural B-cell organization in skeletal muscle identifies subtypes of dermatomyositis. Neurology(R) Neuroimmunology & Neuroinflammation. 5: e451. PMID 29520367 DOI: 10.1212/NXI.0000000000000451  0.098
2013 Dietel M, Jöhrens K, Laffert M, Hummel M, Bläker H, Müller BM, Lehmann A, Denkert C, Heppner FL, Koch A, Sers C, Anagnostopoulos I. Predictive molecular pathology and its role in targeted cancer therapy: a review focussing on clinical relevance. Cancer Gene Therapy. 20: 211-21. PMID 23492822 DOI: 10.1038/cgt.2013.13  0.098
1998 Heppner F, Skutella T, Hailer N, Haas D, Nitsch R. Activated microglial cells migrate towards sites of excitotoxic neuronal injury inside organotypic hippocampal slice cultures Journal of Neuroimmunology. 90: 28. DOI: 10.1016/S0165-5728(98)91346-7  0.097
2019 Çakmak-Görür N, Radke J, Rhein S, Schumann E, Willimsky G, Heppner FL, Blankenstein T, Pezzutto A. Intracellular expression of FLT3 in Purkinje cells: implications for adoptive T-cell therapies. Leukemia. PMID 30607022 DOI: 10.1038/s41375-018-0330-7  0.097
2016 Lohkamp LN, Schinz M, Gehlhaar C, Guse K, Thomale UW, Vajkoczy P, Heppner FL, Koch A. MGMT Promoter Methylation and BRAF V600E Mutations Are Helpful Markers to Discriminate Pleomorphic Xanthoastrocytoma from Giant Cell Glioblastoma. Plos One. 11: e0156422. PMID 27253461 DOI: 10.1371/journal.pone.0156422  0.096
2023 Aschman T, Wyler E, Baum O, Hentschel A, Rust R, Legler F, Preusse C, Meyer-Arndt L, Büttnerova I, Förster A, Cengiz D, Alves LGT, Schneider J, Kedor C, Bellmann-Strobl J, ... ... Heppner FL, et al. Post-COVID exercise intolerance is associated with capillary alterations and immune dysregulations in skeletal muscles. Acta Neuropathologica Communications. 11: 193. PMID 38066589 DOI: 10.1186/s40478-023-01662-2  0.096
2008 Ingold B, Wild PJ, Nocito A, Amin MB, Storz M, Heppner FL, Moch H. Renal cell carcinoma marker reliably discriminates central nervous system haemangioblastoma from brain metastases of renal cell carcinoma. Histopathology. 52: 674-81. PMID 18393979 DOI: 10.1111/j.1365-2559.2008.03003.x  0.096
2009 Ingold B, Schraml P, Heppner FL, Moch H. Homogeneous MGMT immunoreactivity correlates with an unmethylated MGMT promoter status in brain metastases of various solid tumors. Plos One. 4: e4775. PMID 19274096 DOI: 10.1371/journal.pone.0004775  0.095
2014 Lohkamp LN, von Au K, Goebel HH, Kress W, Grieben U, Drossel K, Garbes L, Wirth B, Heppner FL, Stenzel W. A paucisymptomatic neuromuscular disease mimicking type III 5q-SMA with complex rearrangements in the SMN gene. Journal of Child Neurology. 29: 254-9. PMID 24334346 DOI: 10.1177/0883073813511858  0.092
2007 D'cunja J, Shalaby T, Rivera P, von Büren A, Patti R, Heppner FL, Arcaro A, Rorke-Adams LB, Phillips PC, Grotzer MA. Antisense treatment of IGF-IR induces apoptosis and enhances chemosensitivity in central nervous system atypical teratoid/rhabdoid tumours cells. European Journal of Cancer (Oxford, England : 1990). 43: 1581-9. PMID 17446062 DOI: 10.1016/J.Ejca.2007.03.003  0.089
2023 Muench A, Teichmann D, Spille D, Kuzman P, Perez E, May SA, Mueller WC, Kombos T, Nazari-Dehkordi S, Onken J, Vajkoczy P, Ntoulias G, Bettencourt C, von Deimling A, Paulus W, ... Heppner FL, et al. A Novel Type of IDH Wild-type Glioma Characterized by Gliomatosis Cerebri-like Growth Pattern, TERT Promoter Mutation, and Distinct Epigenetic Profile. The American Journal of Surgical Pathology. PMID 37737691 DOI: 10.1097/PAS.0000000000002118  0.089
2015 Radke J, Gehlhaar C, Lenze D, Capper D, Bock A, Heppner FL, Jödicke A, Koch A. The evolution of the anaplastic cerebellar liponeurocytoma: case report and review of the literature. Clinical Neuropathology. 34: 19-25. PMID 25250652 DOI: 10.5414/NP300783  0.085
2010 Zietsch J, Ziegenhagen N, Heppner FL, Reuss D, von Deimling A, Holtkamp N. The 4q12 amplicon in malignant peripheral nerve sheath tumors: consequences on gene expression and implications for sunitinib treatment. Plos One. 5: e11858. PMID 20686603 DOI: 10.1371/journal.pone.0011858  0.084
2017 Onken J, Vajkoczy P, Torka R, Hempt C, Patsouris V, Heppner FL, Radke J. Phospho-AXL is widely expressed in glioblastoma and associated with significant shorter overall survival. Oncotarget. 8: 50403-50414. PMID 28881571 DOI: 10.18632/oncotarget.18468  0.082
2005 Salemi S, Aeschlimann A, Reisch N, Jüngel A, Gay RE, Heppner FL, Michel BA, Gay S, Sprott H. Detection of kappa and delta opioid receptors in skin--outside the nervous system. Biochemical and Biophysical Research Communications. 338: 1012-7. PMID 16263089 DOI: 10.1016/j.bbrc.2005.10.072  0.082
2021 Greuel S, Ihlow J, Dragomir MP, Streit S, Corman VM, Haberbosch L, Winkler D, Meinhardt J, Aschman T, Schneider J, Trotsyuk I, Kunze CA, Maurer L, Radbruch H, Heppner FL, et al. COVID-19: Autopsy findings in six patients between 26 and 46 years of age. International Journal of Infectious Diseases : Ijid : Official Publication of the International Society For Infectious Diseases. PMID 34089883 DOI: 10.1016/j.ijid.2021.05.069  0.081
2008 Murat A, Migliavacca E, Gorlia T, Lambiv WL, Shay T, Hamou MF, de Tribolet N, Regli L, Wick W, Kouwenhoven MC, Hainfellner JA, Heppner FL, Dietrich PY, Zimmer Y, Cairncross JG, et al. Stem cell-related "self-renewal" signature and high epidermal growth factor receptor expression associated with resistance to concomitant chemoradiotherapy in glioblastoma. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 26: 3015-24. PMID 18565887 DOI: 10.1200/Jco.2007.15.7164  0.08
2020 Schweizer L, Thierfelder F, Thomas C, Soschinski P, Suwala A, Stichel D, Wefers AK, Wessels L, Misch M, Kim HY, Jödicke R, Teichmann D, Kaul D, Kahn J, Bockmayr M, ... ... Heppner FL, et al. Molecular characterization of CNS paragangliomas identifies cauda equina paragangliomas as a distinct tumor entity. Acta Neuropathologica. PMID 32926213 DOI: 10.1007/s00401-020-02218-7  0.08
2009 Stenzel W, Heppner FL, Goebel HH, Alten RH. Macrophagic Myofasciitis. Deutsches ã„Rzteblatt International. 106: 248. PMID 19547641 DOI: 10.3238/arztebl.2009.0248a  0.077
2022 Kuschel LP, Hench J, Frank S, Hench IB, Girard E, Blanluet M, Masliah-Planchon J, Misch M, Onken J, Czabanka M, Yuan D, Lukassen S, Karau P, Ishaque N, Hain EG, ... Heppner F, et al. Robust methylation-based classification of brain tumours using nanopore sequencing. Neuropathology and Applied Neurobiology. e12856. PMID 36269599 DOI: 10.1111/nan.12856  0.077
2021 Aschman T, Schneider J, Greuel S, Meinhardt J, Streit S, Goebel HH, Büttnerova I, Elezkurtaj S, Scheibe F, Radke J, Meisel C, Drosten C, Radbruch H, Heppner FL, Corman VM, et al. Association Between SARS-CoV-2 Infection and Immune-Mediated Myopathy in Patients Who Have Died. Jama Neurology. PMID 34115106 DOI: 10.1001/jamaneurol.2021.2004  0.076
2007 Hewer E, Danek A, Schoser BG, Miranda M, Reichard R, Castiglioni C, Oechsner M, Goebel HH, Heppner FL, Jung HH. McLeod myopathy revisited: more neurogenic and less benign. Brain : a Journal of Neurology. 130: 3285-96. PMID 18055495 DOI: 10.1093/brain/awm269  0.075
2021 Elezkurtaj S, Greuel S, Ihlow J, Michaelis EG, Bischoff P, Kunze CA, Sinn BV, Gerhold M, Hauptmann K, Ingold-Heppner B, Miller F, Herbst H, Corman VM, Martin H, Radbruch H, ... Heppner FL, et al. Causes of death and comorbidities in hospitalized patients with COVID-19. Scientific Reports. 11: 4263. PMID 33608563 DOI: 10.1038/s41598-021-82862-5  0.074
2013 Preusse C, Goebel H, Moers Av, Heppner F, Stenzel W. P.20.3 Targeting fibrosis and inflammation in Duchenne Muscular Dystrophy Neuromuscular Disorders. 23: 839. DOI: 10.1016/j.nmd.2013.06.693  0.074
2021 Thomas C, Thierfelder F, Träger M, Soschinski P, Müther M, Edelmann D, Förster A, Geiler C, Kim HY, Filipski K, Harter PN, Schittenhelm J, Eckert F, Ntoulias G, May SA, ... ... Heppner FL, et al. TERT promoter mutation and chromosome 6 loss define a high-risk subtype of ependymoma evolving from posterior fossa subependymoma. Acta Neuropathologica. PMID 33755803 DOI: 10.1007/s00401-021-02300-8  0.073
2015 Arnold A, Bahra M, Lenze D, Bradtmöller M, Guse K, Gehlhaar C, Bläker H, Heppner FL, Koch A. Genome wide DNA copy number analysis in cholangiocarcinoma using high resolution molecular inversion probe single nucleotide polymorphism assay. Experimental and Molecular Pathology. 99: 344-53. PMID 26260902 DOI: 10.1016/j.yexmp.2015.08.003  0.071
1967 Hamilton WJ, Gilbert WM, Heppner FH, Planck RJ. Starling Roost Dispersal and a Hypothetical Mechanism Regulating Rhthmical Animal Movement to and from Dispersal Centers. Ecology. 48: 825-833. PMID 34493026 DOI: 10.2307/1933740  0.07
2021 Dittmayer C, Goebel HH, Heppner FL, Stenzel W, Bachmann S. Preparation of Samples for Large-Scale Automated Electron Microscopy of Tissue and Cell Ultrastructure. Microscopy and Microanalysis : the Official Journal of Microscopy Society of America, Microbeam Analysis Society, Microscopical Society of Canada. 27: 815-827. PMID 34266508 DOI: 10.1017/S1431927621011958  0.066
2005 Heppner FL. [AM-05]: Immunotherapy, intra and intra-CNS actions Alzheimer's & Dementia. 1: S1-S2. DOI: 10.1016/j.jalz.2005.06.032  0.063
2011 Hegi ME, Diserens AC, Bady P, Kamoshima Y, Kouwenhoven MC, Delorenzi M, Lambiv WL, Hamou MF, Matter MS, Koch A, Heppner FL, Yonekawa Y, Merlo A, Frei K, Mariani L, et al. Pathway analysis of glioblastoma tissue after preoperative treatment with the EGFR tyrosine kinase inhibitor gefitinib--a phase II trial. Molecular Cancer Therapeutics. 10: 1102-12. PMID 21471286 DOI: 10.1158/1535-7163.MCT-11-0048  0.062
2023 Habringer S, Demel UM, Fietz AK, Lammer F, Schroers R, Hofer S, Bairey O, Braess J, Meier-Stiegen AS, Stuhlmann R, Schmidt-Hieber M, Hoffmann J, Zinngrebe B, Kaiser U, Reimer P, ... ... Heppner FL, et al. A prospective observational study of real-world treatment and outcome in secondary CNS lymphoma. European Journal of Cancer (Oxford, England : 1990). 196: 113436. PMID 38008033 DOI: 10.1016/j.ejca.2023.113436  0.061
2013 Buschmann CT, Stenzel W, Martin H, Heppner FL, Guddat SS, Tsokos M. Calcified myocardial necrosis in pediatric patients after cardiopulmonary resuscitation. Forensic Science, Medicine, and Pathology. 9: 543-50. PMID 23264200 DOI: 10.1007/s12024-012-9400-8  0.059
2022 Jurmeister P, Glöß S, Roller R, Leitheiser M, Schmid S, Mochmann LH, Payá Capilla E, Fritz R, Dittmayer C, Friedrich C, Thieme A, Keyl P, Jarosch A, Schallenberg S, Bläker H, ... ... Heppner F, et al. DNA methylation-based classification of sinonasal tumors. Nature Communications. 13: 7148. PMID 36443295 DOI: 10.1038/s41467-022-34815-3  0.058
2018 Winterer G, Androsova G, Bender O, Boraschi D, Borchers F, Dschietzig TB, Feinkohl I, Fletcher P, Gallinat J, Hadzidiakos D, Haynes JD, Heppner F, Hetzer S, Hendrikse J, Ittermann B, et al. Personalized risk prediction of postoperative cognitive impairment - rationale for the EU-funded BioCog project. European Psychiatry : the Journal of the Association of European Psychiatrists. PMID 29398565 DOI: 10.1016/J.Eurpsy.2017.10.004  0.056
2019 Radke J, Koch A, Pritsch F, Schumann E, Misch M, Hempt C, Lenz K, Löbel F, Paschereit F, Heppner FL, Vajkoczy P, Koll R, Onken J. Predictive MGMT status in a homogeneous cohort of IDH wildtype glioblastoma patients. Acta Neuropathologica Communications. 7: 7. PMID 31167648 DOI: 10.1186/s40478-019-0745-z  0.055
2016 Kühnen P, Handke D, Waterland RA, Hennig BJ, Silver M, Fulford AJ, Dominguez-Salas P, Moore SE, Prentice AM, Spranger J, Hinney A, Hebebrand J, Heppner FL, Walzer L, Grötzinger C, et al. Interindividual Variation in DNA Methylation at a Putative POMC Metastable Epiallele Is Associated with Obesity. Cell Metabolism. PMID 27568547 DOI: 10.1016/J.Cmet.2016.08.001  0.055
2012 Bady P, Sciuscio D, Diserens AC, Bloch J, van den Bent MJ, Marosi C, Dietrich PY, Weller M, Mariani L, Heppner FL, Mcdonald DR, Lacombe D, Stupp R, Delorenzi M, Hegi ME. MGMT methylation analysis of glioblastoma on the Infinium methylation BeadChip identifies two distinct CpG regions associated with gene silencing and outcome, yielding a prediction model for comparisons across datasets, tumor grades, and CIMP-status. Acta Neuropathologica. 124: 547-60. PMID 22810491 DOI: 10.1007/s00401-012-1016-2  0.055
2024 Goebel HH, Koch A, Radbruch H, Schmid S, Friebel E, Stenzel W, Heppner FL, Capper D. Meeting report of the 20th International Congress of Neuropathology (ICN) 2023 in Berlin. Brain Pathology (Zurich, Switzerland). 34: e13249. PMID 38417806 DOI: 10.1111/bpa.13249  0.053
2015 Nunes JC, Rinnenthal JL, Allenbach Y, Lenze D, Hummel M, Jöhrens K, Walz R, Goebel HH, Heppner FL, Stenzel W. Proximal weakness in a patient with MALT lymphoma: a case report and discussion of possible pathogenesis. Neuropathology and Applied Neurobiology. 41: 686-9. PMID 25763887 DOI: 10.1111/Nan.12234  0.051
2021 Dittmayer C, Meinhardt J, Radbruch H, Radke J, Heppner BI, Heppner FL, Stenzel W, Holland G, Laue M. Using EM data to understand COVID-19 pathophysiology - Authors' reply. Lancet (London, England). 397: 197-198. PMID 33453781 DOI: 10.1016/S0140-6736(21)00032-5  0.049
2013 Czabanka M, Bruenner J, Parmaksiz G, Broggini T, Topalovic M, Bayerl SH, Auf G, Kremenetskaia I, Nieminen M, Jabouille A, Mueller S, Harms U, Harms C, Koch A, Heppner FL, et al. Combined temozolomide and sunitinib treatment leads to better tumour control but increased vascular resistance in O6-methylguanine methyltransferase-methylated gliomas. European Journal of Cancer (Oxford, England : 1990). 49: 2243-52. PMID 23499430 DOI: 10.1016/j.ejca.2013.02.019  0.046
2008 Ingold B, Schraml P, Stopatschinskaja S, Heppner FL, Moch H. Frequent MGMT gene promoter methylation in brain metastases of melanoma, lung, breast and renal carcinoma Journal of Clinical Oncology. 26: 2063-2063. DOI: 10.1200/JCO.2008.26.15_SUPPL.2063  0.045
2003 Baumert BG, Lutterbach J, Bernays R, Davis JB, Heppner FL. Fractionated stereotactic radiotherapy boost after post-operative radiotherapy in patients with high-grade gliomas. Radiotherapy and Oncology : Journal of the European Society For Therapeutic Radiology and Oncology. 67: 183-90. PMID 12812849  0.042
2020 Dittmayer C, Meinhardt J, Radbruch H, Radke J, Heppner BI, Heppner FL, Stenzel W, Holland G, Laue M. Why misinterpretation of electron micrographs in SARS-CoV-2-infected tissue goes viral. Lancet (London, England). PMID 33031763 DOI: 10.1016/S0140-6736(20)32079-1  0.042
2022 Müller M, Ingold-Heppner B, Stocker H, Heppner FL, Dittmayer C, Laue M. Electron microscopy images of monkeypox virus infection in 24-year-old man. Lancet (London, England). 400: 1618. PMID 36252575 DOI: 10.1016/S0140-6736(22)01969-9  0.037
2021 Ochs M, Timm S, Elezkurtaj S, Horst D, Meinhardt J, Heppner FL, Weber-Carstens S, Hocke AC, Witzenrath M. Collapse induration of alveoli is an ultrastructural finding in a COVID-19 patient. The European Respiratory Journal. PMID 33446606 DOI: 10.1183/13993003.04165-2020  0.033
2007 Heppner FH, Gabel JE, March K. Avian flight without visual reference: preflight spinning produces spatial disorientation. Aviation, Space, and Environmental Medicine. 78: 43-7. PMID 17225481  0.025
2015 Radke J, Gehlhaar C, Lenze D, Capper D, Bock A, Heppner FL, Jödicke A, Koch A. The evolution of the anaplastic cerebellar liponeurocytoma: Case report and review of the literature Clinical Neuropathology. 34: 19-25. DOI: 10.5414/NP300783  0.024
2023 Müller M, Ingold-Heppner B, Stocker H, Heppner FL, Dittmayer C, Laue M. Skin lesion specimens as first choice to detect monkeypox virus - Authors' reply. Lancet (London, England). 401: 1265. PMID 37061265 DOI: 10.1016/S0140-6736(23)00271-4  0.023
2006 Ingold B, Moschopulos M, Hutter G, Seeger H, Röthlisberger B, Landolt H, Yonekawa Y, Jochum W, Heppner FL. Abdominal seeding of an atypical teratoid/rhabdoid tumor of the pineal gland along a ventriculoperitoneal shunt catheter [2] Acta Neuropathologica. 111: 56-59. PMID 16328512 DOI: 10.1007/S00401-005-1112-7  0.015
2021 Jank P, Gehlhaar C, Lederer B, Fontanella C, Schneeweiss A, Karn T, Marmé F, Sinn HP, van Mackelenbergh M, Sinn B, Zahm DM, Ingold-Heppner B, Schem C, Stickeler E, Fasching PA, ... ... Heppner F, et al. Correction: MGMT promoter methylation in triple negative breast cancer of the GeparSixto trial. Plos One. 16: e0257142. PMID 34469495 DOI: 10.1371/journal.pone.0257142  0.01
2021 Bittner A, Radke J, Eurich D, Wiener E, Denker S, Anagnostopoulos I, Na IK, Heppner FL, Bullinger L, Schmitt CA. Cerebral EBV-positive PTLD controlled by PD-1 checkpoint blockade in a liver transplant patient. Leukemia & Lymphoma. 1-4. PMID 33612072 DOI: 10.1080/10428194.2021.1889537  0.01
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