Xia Shen - Publications

Affiliations: 
University of Edinburgh, Edinburgh, Scotland, United Kingdom 

37 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Repetto L, Chen J, Yang Z, Zhai R, Timmers PRHJ, Feng X, Li T, Yao Y, Maslov D, Timoshchuk A, Tu F, Twait EL, May-Wilson S, Muckian MD, Prins BP, ... ... Shen X, et al. The genetic landscape of neuro-related proteins in human plasma. Nature Human Behaviour. PMID 39210026 DOI: 10.1038/s41562-024-01963-z  0.618
2024 Young WJ, van der Most PJ, Bartz TM, Bos MM, Biino G, Duong T, Foco L, Lominchar JT, Müller-Nurasyid M, Nardone GG, Pecori A, Ramirez J, Repetto L, Schramm K, Shen X, et al. Genome-Wide Interaction Analyses of Serum Calcium on Ventricular Repolarization Time in 125 393 Participants. Journal of the American Heart Association. e034760. PMID 39206732 DOI: 10.1161/JAHA.123.034760  0.568
2024 Feng X, Zan Y, Li T, Yao Y, Ning Z, Li J, Charati H, Xu W, Wan Q, Zeng D, Zeng Z, Liu Y, Shen X. Dual-trait genomic analysis in highly stratified Arabidopsis thaliana populations using genome-wide association summary statistics. Heredity. PMID 38822132 DOI: 10.1038/s41437-024-00688-z  0.327
2024 Smith-Byrne K, Hedman Å, Dimitriou M, Desai T, Sokolov AV, Schioth HB, Koprulu M, Pietzner M, Langenberg C, Atkins J, Penha RC, McKay J, Brennan P, Zhou S, Richards BJ, ... ... Shen X, et al. Identifying therapeutic targets for cancer among 2074 circulating proteins and risk of nine cancers. Nature Communications. 15: 3621. PMID 38684708 DOI: 10.1038/s41467-024-46834-3  0.507
2023 Repetto L, Chen J, Yang Z, Zhai R, Timmers P, Li T, Twait E, May-Wilson S, Muckian M, Prins B, Png G, Kooperberg C, Johansson Å, Hillary R, Wheeler E, ... ... Shen X, et al. Unraveling Neuro-Proteogenomic Landscape and Therapeutic Implications for Human Behaviors and Psychiatric Disorders. Research Square. PMID 37034613 DOI: 10.21203/rs.3.rs-2720355/v1  0.61
2023 Young WJ, Haessler J, Benjamins JW, Repetto L, Yao J, Isaacs A, Harper AR, Ramirez J, Garnier S, van Duijvenboden S, Baldassari AR, Concas MP, Duong T, Foco L, Isaksen JL, ... ... Shen X, et al. Genetic architecture of spatial electrical biomarkers for cardiac arrhythmia and relationship with cardiovascular disease. Nature Communications. 14: 1411. PMID 36918541 DOI: 10.1038/s41467-023-36997-w  0.584
2023 Yuan S, Wang L, Zhang H, Xu F, Zhou X, Yu L, Sun J, Chen J, Ying H, Xu X, Yu Y, Spiliopoulou A, Shen X, Wilson J, Gill D, et al. Mendelian randomization and clinical trial evidence supports TYK2 inhibition as a therapeutic target for autoimmune diseases. Ebiomedicine. 89: 104488. PMID 36842216 DOI: 10.1016/j.ebiom.2023.104488  0.539
2023 Repetto L, Chen J, Yang Z, Zhai R, Timmers PRHJ, Li T, Twait EL, May-Wilson S, Muckian MD, Prins BP, Png G, Kooperberg C, Johansson Å, Hillary RF, Wheeler E, ... ... Shen X, et al. Genetic mechanisms of 184 neuro-related proteins in human plasma. Medrxiv : the Preprint Server For Health Sciences. PMID 36824751 DOI: 10.1101/2023.02.10.23285650  0.623
2022 Young WJ, Lahrouchi N, Isaacs A, Duong T, Foco L, Ahmed F, Brody JA, Salman R, Noordam R, Benjamins JW, Haessler J, Lyytikäinen LP, Repetto L, Concas MP, van den Berg ME, ... ... Shen X, et al. Genetic analyses of the electrocardiographic QT interval and its components identify additional loci and pathways. Nature Communications. 13: 5144. PMID 36050321 DOI: 10.1038/s41467-022-32821-z  0.607
2022 Yang Z, MacDonald-Dunlop E, Chen J, Zhai R, Li T, Richmond A, Klaric L, Pirastu N, Ning Z, Zheng C, Wang Y, Huang T, He Y, Guo H, Ying K, ... ... Shen X, et al. Genetic Landscape of the ACE2 Coronavirus Receptor. Circulation. PMID 35387486 DOI: 10.1161/CIRCULATIONAHA.121.057888  0.333
2021 Png G, Barysenka A, Repetto L, Navarro P, Shen X, Pietzner M, Wheeler E, Wareham NJ, Langenberg C, Tsafantakis E, Karaleftheri M, Dedoussis G, Mälarstig A, Wilson JF, Gilly A, et al. Mapping the serum proteome to neurological diseases using whole genome sequencing. Nature Communications. 12: 7042. PMID 34857772 DOI: 10.1038/s41467-021-27387-1  0.626
2021 Zhu H, Zheng F, Li L, Jin Y, Luo Y, Li Z, Zeng J, Tang L, Li Z, Xia N, Liu P, Han D, Shan Y, Zhu X, Liu S, ... ... Shen X, et al. A Chinese host genetic study discovered IFNs and causality of laboratory traits on COVID-19 severity. Iscience. 103186. PMID 34608450 DOI: 10.1016/j.isci.2021.103186  0.329
2021 Li T, Ning Z, Yang Z, Zhai R, Zheng C, Xu W, Wang Y, Ying K, Chen Y, Shen X. Total genetic contribution assessment across the human genome. Nature Communications. 12: 2845. PMID 33990588 DOI: 10.1038/s41467-021-23124-w  0.311
2020 Ning Z, Pawitan Y, Shen X. High-definition likelihood inference of genetic correlations across human complex traits. Nature Genetics. PMID 32601477 DOI: 10.1038/S41588-020-0653-Y  0.409
2020 Luo R, Zheng C, Yang H, Chen X, Jiang P, Wu X, Yang Z, Shen X, Li X. Identification of potential candidate genes and pathways in atrioventricular nodal reentry tachycardia by whole-exome sequencing. Clinical and Translational Medicine. 10: 238-257. PMID 32508047 DOI: 10.1002/Ctm2.25  0.331
2019 Wu D, Yan J, Shen X, Sun Y, Thulin M, Cai Y, Wik L, Shen Q, Oelrich J, Qian X, Dubois KL, Ronquist KG, Nilsson M, Landegren U, Kamali-Moghaddam M. Profiling surface proteins on individual exosomes using a proximity barcoding assay. Nature Communications. 10: 3854. PMID 31451692 DOI: 10.1038/S41467-019-11486-1  0.3
2019 Noordam R, Young WJ, Salman R, Kanters JK, van den Berg ME, van Heemst D, Lin HJ, Barreto SM, Biggs ML, Biino G, Catamo E, Concas MP, Ding J, Evans DS, Foco L, ... ... Shen X, et al. Effects of Calcium, Magnesium, and Potassium Concentrations on Ventricular Repolarization in Unselected Individuals. Journal of the American College of Cardiology. 73: 3118-3131. PMID 31221261 DOI: 10.1016/J.Jacc.2019.03.519  0.557
2018 Li X, Meng X, Spiliopoulou A, Timofeeva M, Wei WQ, Gifford A, Shen X, He Y, Varley T, McKeigue P, Tzoulaki I, Wright AF, Joshi P, Denny JC, Campbell H, et al. MR-PheWAS: exploring the causal effect of SUA level on multiple disease outcomes by using genetic instruments in UK Biobank. Annals of the Rheumatic Diseases. PMID 29437585 DOI: 10.1136/Annrheumdis-2017-212534  0.308
2017 Ning Z, Lee Y, Joshi PK, Wilson JF, Pawitan Y, Shen X. A Selection Operator for Summary Association Statistics Reveals Allelic Heterogeneity of Complex Traits. American Journal of Human Genetics. 101: 903-912. PMID 29198721 DOI: 10.1016/J.Ajhg.2017.09.027  0.416
2017 Joshi PK, Pirastu N, Kentistou KA, Fischer K, Hofer E, Schraut KE, Clark DW, Nutile T, Barnes CLK, Timmers PRHJ, Shen X, Gandin I, McDaid AF, Hansen TF, Gordon SD, et al. Genome-wide meta-analysis associates HLA-DQA1/DRB1 and LPA and lifestyle factors with human longevity. Nature Communications. 8: 910. PMID 29030599 DOI: 10.1038/S41467-017-00934-5  0.366
2017 Shen X, Klarić L, Sharapov S, Mangino M, Ning Z, Wu D, Trbojević-Akmačić I, Pučić-Baković M, Rudan I, Polašek O, Hayward C, Spector TD, Wilson JF, Lauc G, Aulchenko YS. Multivariate discovery and replication of five novel loci associated with Immunoglobulin G N-glycosylation. Nature Communications. 8: 447. PMID 28878392 DOI: 10.1038/S41467-017-00453-3  0.381
2017 Wang B, Li Z, Xu W, Feng X, Wan Q, Zan Y, Sheng S, Shen X. Bivariate genomic analysis identifies a hidden locus associated with bacteria hypersensitive response in Arabidopsis thaliana. Scientific Reports. 7: 45281. PMID 28338080 DOI: 10.1038/Srep45281  0.405
2016 Barban N, Jansen R, de Vlaming R, Vaez A, Mandemakers JJ, Tropf FC, Shen X, Wilson JF, Chasman DI, Nolte IM, Tragante V, van der Laan SW, Perry JR, Kong A, et al. Genome-wide analysis identifies 12 loci influencing human reproductive behavior. Nature Genetics. PMID 27798627 DOI: 10.1038/Ng.3698  0.438
2016 Zan Y, Shen X, Forsberg S, Carlborg O. Genetic Regulation of Transcriptional Variation in Natural Arabidopsis thaliana Accessions. G3 (Bethesda, Md.). PMID 27226169 DOI: 10.1534/G3.116.030874  0.35
2015 Lachowiec J, Shen X, Queitsch C, Carlborg Ö. A Genome-Wide Association Analysis Reveals Epistatic Cancellation of Additive Genetic Variance for Root Length in Arabidopsis thaliana. Plos Genetics. 11: e1005541. PMID 26397943 DOI: 10.1371/Journal.Pgen.1005541  0.449
2015 Besnier F, Glover KA, Lien S, Kent M, Hansen MM, Shen X, Skaala Ø. Identification of quantitative genetic components of fitness variation in farmed, hybrid and native salmon in the wild. Heredity. 115: 47-55. PMID 26059968 DOI: 10.1038/Hdy.2015.15  0.362
2014 Shen X, De Jonge J, Forsberg SK, Pettersson ME, Sheng Z, Hennig L, Carlborg Ö. Natural CMT2 variation is associated with genome-wide methylation changes and temperature seasonality. Plos Genetics. 10: e1004842. PMID 25503602 DOI: 10.1371/Journal.Pgen.1004842  0.381
2014 Shen X, Li Y, Rönnegård L, Udén P, Carlborg Ö. Application of a genomic model for high‐dimensional chemometric analysis Journal of Chemometrics. 28: 548-557. DOI: 10.1002/Cem.2614  0.395
2013 Shen X, Rönnegård L. Issues with data transformation in genome-wide association studies for phenotypic variability. F1000research. 2: 200. PMID 24555098 DOI: 10.12688/F1000Research.2-200.V1  0.368
2013 Shen X. The curse of the missing heritability. Frontiers in Genetics. 4: 225. PMID 24204378 DOI: 10.3389/Fgene.2013.00225  0.34
2013 Nelson RM, Nettelblad C, Pettersson ME, Shen X, Crooks L, Besnier F, Alvarez-Castro JM, Rönnegård L, Ek W, Sheng Z, Kierczak M, Holmgren S, Carlborg O. MAPfastR: quantitative trait loci mapping in outbred line crosses. G3 (Bethesda, Md.). 3: 2147-9. PMID 24122053 DOI: 10.1534/G3.113.008623  0.322
2013 Shen X, Carlborg O. Beware of risk for increased false positive rates in genome-wide association studies for phenotypic variability. Frontiers in Genetics. 4: 93. PMID 23734164 DOI: 10.3389/Fgene.2013.00093  0.332
2013 Shen X, Alam M, Fikse F, Rönnegård L. A novel generalized ridge regression method for quantitative genetics. Genetics. 193: 1255-68. PMID 23335338 DOI: 10.1534/Genetics.112.146720  0.357
2012 Shen X, Pettersson M, Rönnegård L, Carlborg Ö. Inheritance beyond plain heritability: variance-controlling genes in Arabidopsis thaliana. Plos Genetics. 8: e1002839. PMID 22876191 DOI: 10.1371/Journal.Pgen.1002839  0.368
2012 Nelson RM, Li X, Shen X, Carlborg Ö. Variance controlling genes and epistasis – new opportunities in genetical genomics F1000research. 3. DOI: 10.7490/F1000Research.1090903.1  0.375
2011 Shen X, Rönnegård L, Carlborg O. How to deal with genotype uncertainty in variance component quantitative trait loci analyses. Genetics Research. 93: 333-42. PMID 21767456 DOI: 10.1017/S0016672311000152  0.364
2011 Shen X, Rönnegård L, Carlborg O. Hierarchical likelihood opens a new way of estimating genetic values using genome-wide dense marker maps. Bmc Proceedings. 5: S14. PMID 21624170 DOI: 10.1186/1753-6561-5-S3-S14  0.365
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