| Year |
Citation |
Score |
| 2023 |
Kohan AA, Lupien M, Cescon D, Deblois G, Ventura M, Metser U, Veit-Haibach P. Detection of metabolic adaptation in a triple-negative breast cancer animal model with [F]choline-PET imaging as a surrogate for drug resistance. European Journal of Nuclear Medicine and Molecular Imaging. PMID 38095672 DOI: 10.1007/s00259-023-06546-0 |
0.685 |
|
| 2023 |
Grillo G, Keshavarzian T, Linder S, Arlidge C, Mout L, Nand A, Teng M, Qamra A, Zhou S, Kron KJ, Murison A, Hawley JR, Fraser M, van der Kwast TH, Raj GV, ... ... Lupien M, et al. Transposable elements are co-opted as oncogenic regulatory elements by lineage-specific transcription factors in prostate cancer. Cancer Discovery. PMID 37694973 DOI: 10.1158/2159-8290.CD-23-0331 |
0.827 |
|
| 2023 |
Cameron S, Deblois G, Hawley JR, Qamra A, Zhou S, Tonekaboni SAM, Murison A, Van Vliet R, Liu J, Locasale JW, Lupien M. Chronic hypoxia favours adoption to a castration-resistant cell state in prostate cancer. Oncogene. PMID 37020039 DOI: 10.1038/s41388-023-02680-z |
0.813 |
|
| 2022 |
Yanchus C, Drucker KL, Kollmeyer TM, Tsai R, Winick-Ng W, Liang M, Malik A, Pawling J, De Lorenzo SB, Ali A, Decker PA, Kosel ML, Panda A, Al-Zahrani KN, Jiang L, ... ... Lupien M, et al. A noncoding single-nucleotide polymorphism at 8q24 drives -mutant glioma formation. Science (New York, N.Y.). 378: 68-78. PMID 36201590 DOI: 10.1126/science.abj2890 |
0.786 |
|
| 2022 |
Bahl S, Carroll JS, Lupien M. Chromatin Variants Reveal the Genetic Determinants of Oncogenesis in Breast Cancer. Cold Spring Harbor Perspectives in Medicine. PMID 36041880 DOI: 10.1101/cshperspect.a041322 |
0.617 |
|
| 2022 |
Wu Q, Nie DY, Ba-Alawi W, Ji Y, Zhang Z, Cruickshank J, Haight J, Ciamponi FE, Chen J, Duan S, Shen Y, Liu J, Marhon SA, Mehdipour P, Szewczyk MM, ... ... Lupien M, et al. PRMT inhibition induces a viral mimicry response in triple-negative breast cancer. Nature Chemical Biology. PMID 35578032 DOI: 10.1038/s41589-022-01024-4 |
0.76 |
|
| 2021 |
Richards LM, Whitley OKN, MacLeod G, Cavalli FMG, Coutinho FJ, Jaramillo JE, Svergun N, Riverin M, Croucher DC, Kushida M, Yu K, Guilhamon P, Rastegar N, Ahmadi M, Bhatti JK, ... ... Lupien M, et al. Gradient of Developmental and Injury Response transcriptional states defines functional vulnerabilities underpinning glioblastoma heterogeneity. Nature Cancer. 2: 157-173. PMID 35122077 DOI: 10.1038/s43018-020-00154-9 |
0.757 |
|
| 2021 |
Payer LM, Steranka JP, Kryatova MS, Grillo G, Lupien M, Rocha PP, Burns KH. insertion variants alter gene transcript levels. Genome Research. PMID 34799402 DOI: 10.1101/gr.261305.120 |
0.44 |
|
| 2021 |
Nikolic A, Singhal D, Ellestad K, Johnston M, Shen Y, Gillmor A, Morrissy S, Cairncross JG, Jones S, Lupien M, Chan JA, Neri P, Bahlis N, Gallo M. Copy-scAT: Deconvoluting single-cell chromatin accessibility of genetic subclones in cancer. Science Advances. 7: eabg6045. PMID 34644115 DOI: 10.1126/sciadv.abg6045 |
0.623 |
|
| 2021 |
Hawley JR, Zhou S, Arlidge C, Grillo G, Kron KJ, Hugh-White R, van der Kwast TH, Fraser M, Boutros PC, Bristow RG, Lupien M. Reorganization of the 3D genome pinpoints non-coding drivers of primary prostate tumors. Cancer Research. PMID 34642184 DOI: 10.1158/0008-5472.CAN-21-2056 |
0.807 |
|
| 2021 |
El Ghamrasni S, Quevedo R, Hawley J, Mazrooei P, Hanna Y, Cirlan I, Zhu H, Bruce JP, Oldfield LE, Yang SYC, Guilhamon P, Reimand J, Cescon DW, Done SJ, Lupien M, et al. Mutations in Noncoding -Regulatory Elements Reveal Cancer Driver Cistromes in Luminal Breast Cancer. Molecular Cancer Research : McR. PMID 34556523 DOI: 10.1158/1541-7786.MCR-21-0471 |
0.81 |
|
| 2021 |
Ahmed M, Soares F, Xia JH, Yang Y, Li J, Guo H, Su P, Tian Y, Lee HJ, Wang M, Akhtar N, Houlahan KE, Bosch A, Zhou S, Mazrooei P, ... ... Lupien M, et al. CRISPRi screens reveal a DNA methylation-mediated 3D genome dependent causal mechanism in prostate cancer. Nature Communications. 12: 1781. PMID 33741908 DOI: 10.1038/s41467-021-21867-0 |
0.813 |
|
| 2021 |
Sachamitr P, Ho JC, Ciamponi FE, Ba-Alawi W, Coutinho FJ, Guilhamon P, Kushida MM, Cavalli FMG, Lee L, Rastegar N, Vu V, Sánchez-Osuna M, Coulombe-Huntington J, Kanshin E, Whetstone H, ... ... Lupien M, et al. PRMT5 inhibition disrupts splicing and stemness in glioblastoma. Nature Communications. 12: 979. PMID 33579912 DOI: 10.1038/s41467-021-21204-5 |
0.748 |
|
| 2021 |
Guilhamon P, Chesnelong C, Kushida MM, Nikolic A, Singhal D, MacLeod G, Madani Tonekaboni SA, Cavalli FM, Arlidge C, Rajakulendran N, Rastegar N, Hao X, Hassam R, Smith LJ, Whetstone H, ... ... Lupien M, et al. Single-cell chromatin accessibility profiling of glioblastoma identifies an Invasive cancer stem cell population associated with lower survival. Elife. 10. PMID 33427645 DOI: 10.7554/eLife.64090 |
0.802 |
|
| 2020 |
Takayama N, Murison A, Takayanagi SI, Arlidge C, Zhou S, Garcia-Prat L, Chan-Seng-Yue M, Zandi S, Gan OI, Boutzen H, Kaufmann KB, Trotman-Grant A, Schoof E, Kron K, Díaz N, ... ... Lupien M, et al. The Transition from Quiescent to Activated States in Human Hematopoietic Stem Cells Is Governed by Dynamic 3D Genome Reorganization. Cell Stem Cell. PMID 33242413 DOI: 10.1016/j.stem.2020.11.001 |
0.793 |
|
| 2020 |
Teng M, Zhou S, Cai C, Lupien M, He HH. Pioneer of prostate cancer: past, present and the future of FOXA1. Protein & Cell. PMID 32946061 DOI: 10.1007/S13238-020-00786-8 |
0.814 |
|
| 2020 |
Wu Q, Ba-Alawi W, Deblois G, Cruickshank J, Duan S, Lima-Fernandes E, Haight J, Tonekaboni SAM, Fortier AM, Kuasne H, McKee TD, Mahmoud H, Kushida M, Cameron S, Dogan-Artun N, ... ... Lupien M, et al. GLUT1 inhibition blocks growth of RB1-positive triple negative breast cancer. Nature Communications. 11: 4205. PMID 32826891 DOI: 10.1038/S41467-020-18020-8 |
0.8 |
|
| 2020 |
Deblois G, Madani Tonekaboni SA, Grillo G, Martinez C, Kao YI, Tai F, Ettayebi I, Fortier AM, Savage P, Fedor AN, Liu X, Guilhamon P, Lima-Fernandes E, Murison A, Kuasne H, ... ... Lupien M, et al. Epigenetic switch-induced viral mimicry evasion in chemotherapy resistant breast cancer. Cancer Discovery. PMID 32546577 DOI: 10.1158/2159-8290.Cd-19-1493 |
0.812 |
|
| 2020 |
Michealraj KA, Kumar SA, Kim LJY, Cavalli FMG, Przelicki D, Wojcik JB, Delaidelli A, Bajic A, Saulnier O, MacLeod G, Vellanki RN, Vladoiu MC, Guilhamon P, Ong W, Lee JJY, ... ... Lupien M, et al. Metabolic Regulation of the Epigenome Drives Lethal Infantile Ependymoma. Cell. PMID 32445698 DOI: 10.1016/J.Cell.2020.04.047 |
0.798 |
|
| 2020 |
Singh RP, Jeyaraju DV, Voisin V, Hurren R, Xu C, Hawley JR, Barghout SH, Khan DH, Gronda M, Wang X, Jitkova Y, Sharon D, Liyanagae S, MacLean N, Seneviratene AK, ... ... Lupien M, et al. Disrupting Mitochondrial Copper Distribution Inhibits Leukemic Stem Cell Self-Renewal. Cell Stem Cell. PMID 32416059 DOI: 10.1016/J.Stem.2020.04.010 |
0.702 |
|
| 2020 |
Criqui M, Qamra A, Chu TW, Sharma M, Tsao J, Henry DA, Barsyte-Lovejoy D, Arrowsmith CH, Winegarden N, Lupien M, Harrington L. Telomere dysfunction cooperates with epigenetic alterations to impair murine embryonic stem cell fate commitment. Elife. 9. PMID 32297856 DOI: 10.7554/Elife.47333 |
0.809 |
|
| 2020 |
Molyneux SD, Waterhouse PD, Shelton D, Shao YW, Watling CM, Tang QL, Harris IS, Dickson BC, Tharmapalan P, Sandve GK, Zhang X, Bailey SD, Berman H, Wunder JS, Izsvák Z, ... Lupien M, et al. Author Correction: Human somatic cell mutagenesis creates genetically tractable sarcomas. Nature Genetics. PMID 32094913 DOI: 10.1038/S41588-020-0589-2 |
0.71 |
|
| 2020 |
Zhou S, Hawley JR, Soares F, Grillo G, Teng M, Madani Tonekaboni SA, Hua JT, Kron KJ, Mazrooei P, Ahmed M, Arlidge C, Yun HY, Livingstone J, Huang V, Yamaguchi TN, ... ... Lupien M, et al. Noncoding mutations target cis-regulatory elements of the FOXA1 plexus in prostate cancer. Nature Communications. 11: 441. PMID 31974375 DOI: 10.1038/S41467-020-14318-9 |
0.803 |
|
| 2020 |
Zhu H, Uusküla-Reimand L, Isaev K, Wadi L, Alizada A, Shuai S, Huang V, Aduluso-Nwaobasi D, Paczkowska M, Abd-Rabbo D, Ocsenas O, Liang M, Thompson JD, Li Y, Ruan L, ... ... Lupien M, et al. Candidate Cancer Driver Mutations in Distal Regulatory Elements and Long-Range Chromatin Interaction Networks. Molecular Cell. PMID 31954095 DOI: 10.1016/J.Molcel.2019.12.027 |
0.424 |
|
| 2020 |
Criqui M, Qamra A, Chu TW, Sharma M, Tsao J, Henry DA, Barsyte-Lovejoy D, Arrowsmith CH, Winegarden N, Lupien M, Harrington L. Author response: Telomere dysfunction cooperates with epigenetic alterations to impair murine embryonic stem cell fate commitment Elife. DOI: 10.7554/Elife.47333.Sa2 |
0.324 |
|
| 2019 |
Morton AR, Dogan-Artun N, Faber ZJ, MacLeod G, Bartels CF, Piazza MS, Allan KC, Mack SC, Wang X, Gimple RC, Wu Q, Rubin BP, Shetty S, Angers S, Dirks PB, ... ... Lupien M, et al. Functional Enhancers Shape Extrachromosomal Oncogene Amplifications. Cell. 179: 1330-1341.e13. PMID 31761532 DOI: 10.1016/J.Cell.2019.10.039 |
0.378 |
|
| 2019 |
Mazrooei P, Kron KJ, Zhu Y, Zhou S, Grillo G, Mehdi T, Ahmed M, Severson TM, Guilhamon P, Armstrong NS, Huang V, Yamaguchi TN, Fraser M, van der Kwast T, Boutros PC, ... ... Lupien M, et al. Cistrome Partitioning Reveals Convergence of Somatic Mutations and Risk Variants on Master Transcription Regulators in Primary Prostate Tumors. Cancer Cell. PMID 31735626 DOI: 10.1016/J.Ccell.2019.10.005 |
0.808 |
|
| 2019 |
Houlahan KE, Shiah YJ, Gusev A, Yuan J, Ahmed M, Shetty A, Ramanand SG, Yao CQ, Bell C, O'Connor E, Huang V, Fraser M, Heisler LE, Livingstone J, Yamaguchi TN, ... ... Lupien M, et al. Genome-wide germline correlates of the epigenetic landscape of prostate cancer. Nature Medicine. PMID 31591588 DOI: 10.1038/S41591-019-0579-Z |
0.409 |
|
| 2019 |
Madani Tonekaboni SA, Mazrooei P, Kofia V, Haibe-Kains B, Lupien M. Identifying clusters of -regulatory elements underpinning TAD structures and lineage-specific regulatory networks. Genome Research. 29: 1733-1743. PMID 31533978 DOI: 10.1101/Gr.248658.119 |
0.821 |
|
| 2019 |
Krug B, De Jay N, Harutyunyan AS, Deshmukh S, Marchione DM, Guilhamon P, Bertrand KC, Mikael LG, McConechy MK, Chen CCL, Khazaei S, Koncar RF, Agnihotri S, Faury D, Ellezam B, ... ... Lupien M, et al. Pervasive H3K27 Acetylation Leads to ERV Expression and a Therapeutic Vulnerability in H3K27M Gliomas. Cancer Cell. 36: 338-339. PMID 31526762 DOI: 10.1016/j.ccell.2019.08.012 |
0.708 |
|
| 2019 |
Johnston M, Nikolic A, Ninkovic N, Guilhamon P, Cavalli F, Seaman S, Zemp F, Lee J, Abdelkareem A, Ellestad K, Murison A, Kushida M, Coutinho F, Ma Y, Mungall A, ... ... Lupien M, et al. High-resolution structural genomics reveals new therapeutic vulnerabilities in glioblastoma. Genome Research. PMID 31249064 DOI: 10.1101/Gr.246520.118 |
0.812 |
|
| 2019 |
Seneviratne AK, Xu M, Aristizabal Henao JJ, Fajardo VA, Hao Z, Voisin V, Xu GW, Hurren R, Kim S, MacLean N, Wang X, Gronda M, Jeyaraju D, Jitkova Y, Ketela T, ... ... Lupien M, et al. The Mitochondrial Transacylase, Tafazzin, Regulates AML Stemness by Modulating Intracellular Levels of Phospholipids. Cell Stem Cell. 24: 1007. PMID 31173706 DOI: 10.1016/J.Stem.2019.04.020 |
0.67 |
|
| 2019 |
Krug B, De Jay N, Harutyunyan AS, Deshmukh S, Marchione DM, Guilhamon P, Bertrand KC, Mikael LG, McConechy MK, Chen CCL, Khazaei S, Koncar RF, Agnihotri S, Faury D, Ellezam B, ... ... Lupien M, et al. Pervasive H3K27 Acetylation Leads to ERV Expression and a Therapeutic Vulnerability in H3K27M Gliomas. Cancer Cell. 35: 782-797.e8. PMID 31085178 DOI: 10.1016/J.Ccell.2019.04.004 |
0.768 |
|
| 2019 |
Wu Q, Heidenreich D, Zhou S, Ackloo S, Krämer A, Nakka K, Lima-Fernandes E, Deblois G, Duan S, Vellanki RN, Li F, Vedadi M, Dilworth J, Lupien M, Brennan PE, et al. A chemical toolbox for the study of bromodomains and epigenetic signaling. Nature Communications. 10: 1915. PMID 31015424 DOI: 10.1038/S41467-019-09672-2 |
0.788 |
|
| 2019 |
Seneviratne AK, Xu M, Henao JJA, Fajardo VA, Hao Z, Voisin V, Xu GW, Hurren R, Kim S, MacLean N, Wang X, Gronda M, Jeyaraju D, Jitkova Y, Ketela T, ... ... Lupien M, et al. The Mitochondrial Transacylase, Tafazzin, Regulates for AML Stemness by Modulating Intracellular Levels of Phospholipids. Cell Stem Cell. PMID 30930145 DOI: 10.1016/J.Stem.2019.02.020 |
0.688 |
|
| 2019 |
Lima-Fernandes E, Murison A, da Silva Medina T, Wang Y, Ma A, Leung C, Luciani GM, Haynes J, Pollett A, Zeller C, Duan S, Kreso A, Barsyte-Lovejoy D, Wouters BG, Jin J, ... ... Lupien M, et al. Targeting bivalency de-represses Indian Hedgehog and inhibits self-renewal of colorectal cancer-initiating cells. Nature Communications. 10: 1436. PMID 30926792 DOI: 10.1038/S41467-019-09309-4 |
0.383 |
|
| 2019 |
Sinha A, Huang V, Livingstone J, Wang J, Fox NS, Kurganovs N, Ignatchenko V, Fritsch K, Donmez N, Heisler LE, Shiah YJ, Yao CQ, Alfaro JA, Volik S, Lapuk A, ... ... Lupien M, et al. The Proteogenomic Landscape of Curable Prostate Cancer. Cancer Cell. 35: 414-427.e6. PMID 30889379 DOI: 10.1016/J.Ccell.2019.02.005 |
0.752 |
|
| 2019 |
Mehdi T, Bailey SD, Guilhamon P, Lupien M. C3D: a tool to predict 3D genomic interactions between cis-regulatory elements. Bioinformatics (Oxford, England). 35: 877-879. PMID 30816925 DOI: 10.1093/Bioinformatics/Bty717 |
0.796 |
|
| 2019 |
Radulovich N, Tamblyn L, Seo H, Haibe-Kains B, Lupien M, Gilles F, Tsao MS. Abstract B46: Targeting pancreatic cancer organoids with dual BET and CBP/P300 inhibitor NEO2734 Cancer Research. 79. DOI: 10.1158/1538-7445.Panca19-B46 |
0.352 |
|
| 2018 |
Guilhamon P, Lupien M. SMuRF: a novel tool to identify regulatory elements enriched for somatic point mutations. Bmc Bioinformatics. 19: 454. PMID 30477433 DOI: 10.1186/S12859-018-2501-Y |
0.745 |
|
| 2018 |
Hua JT, Ahmed M, Guo H, Zhang Y, Chen S, Soares F, Lu J, Zhou S, Wang M, Li H, Larson NB, McDonnell SK, Patel PS, Liang Y, Yao CQ, ... ... Lupien M, et al. Risk SNP-Mediated Promoter-Enhancer Switching Drives Prostate Cancer through lncRNA PCAT19. Cell. PMID 30033362 DOI: 10.1016/J.Cell.2018.06.014 |
0.806 |
|
| 2018 |
Sonzogni O, Haynes J, Seifried LA, Kamel YM, Huang K, BeGora MD, Yeung FA, Robert-Tissot C, Heng YJ, Yuan X, Wulf GM, Kron KJ, Wagenblast E, Lupien M, Kislinger T, et al. Reporters to mark and eliminate basal or luminal epithelial cells in culture and in vivo. Plos Biology. 16: e2004049. PMID 29924804 DOI: 10.1371/Journal.Pbio.2004049 |
0.722 |
|
| 2018 |
Casey AE, Sinha A, Singhania R, Livingstone J, Waterhouse P, Tharmapalan P, Cruickshank J, Shehata M, Drysdale E, Fang H, Kim H, Isserlin R, Bailey S, Medina T, Deblois G, ... ... Lupien M, et al. Mammary molecular portraits reveal lineage-specific features and progenitor cell vulnerabilities. The Journal of Cell Biology. PMID 29921600 DOI: 10.1083/Jcb.201804042 |
0.815 |
|
| 2018 |
Ghoussaini M, Edwards SL, Michailidou K, Nord S, Cowper-Sal Lari R, Desai K, Kar S, Hillman KM, Kaufmann S, Glubb DM, Beesley J, Dennis J, Bolla MK, Wang Q, Dicks E, ... ... Lupien M, et al. Publisher Correction: Evidence that breast cancer risk at the 2q35 locus is mediated through IGFBP5 regulation. Nature Communications. 9: 16193. PMID 29633761 DOI: 10.1038/Ncomms16193 |
0.795 |
|
| 2018 |
Bailey SD, Zhang X, Desai K, Aid M, Corradin O, Cowper-Sal Lari R, Akhtar-Zaidi B, Scacheri PC, Haibe-Kains B, Lupien M. Publisher Correction: ZNF143 provides sequence specificity to secure chromatin interactions at gene promoters. Nature Communications. 9: 16194. PMID 29633758 DOI: 10.1038/Ncomms16194 |
0.778 |
|
| 2018 |
Bahr C, von Paleske L, Uslu VV, Remeseiro S, Takayama N, Ng SW, Murison A, Langenfeld K, Petretich M, Scognamiglio R, Zeisberger P, Benk AS, Amit I, Zandstra PW, Lupien M, et al. A Myc enhancer cluster regulates normal and leukaemic haematopoietic stem cell hierarchies. Nature. PMID 29342133 DOI: 10.1038/Nature25193 |
0.4 |
|
| 2018 |
Garcia Prat L, Dobson SM, Chan-Seng-Yue M, Vanner R, Murison A, Wintersinger J, Waanders E, Gan OI, McLeod J, Payne-Turner D, Edmonson M, Gu Z, Ma X, Fan Y, Gupta P, ... ... Lupien M, et al. Relapse-Initiating Clones Preexisting at Diagnosis in B- Cell Acute Lymphoblastic Leukemia Help Predict Molecular Pathways of Relapse Blood. 132: 915-915. DOI: 10.1182/Blood-2018-99-118998 |
0.363 |
|
| 2018 |
Ng SW, Xie SZ, Wagenblast E, Takayama N, Jin L, Mbong N, Murison A, Erwin SE, Mitchell A, Van Galen P, Lupien M, Minden MD, Wang JC, Zandstra PW, Dick JE. Identification of Gene Regulatory Networks Governing Stemness Properties of Human HSC and LSC Blood. 132: 3832-3832. DOI: 10.1182/Blood-2018-99-114314 |
0.377 |
|
| 2018 |
Xie SZ, Garcia Prat L, Voisin V, Murison A, Gan OI, Ferrari R, Takayama N, Kaufmann KB, Patel I, Lee E, Holmes G, Medina T, Vedi A, Luberto C, Bader GD, ... ... Lupien M, et al. Sphingolipid Perturbation Activates Proteostasis Programs to Govern Human Hematopoietic Stem Cell Self-Renewal Blood. 132: 170-170. DOI: 10.1182/Blood-2018-170 |
0.366 |
|
| 2017 |
Mack SC, Pajtler KW, Chavez L, Okonechnikov K, Bertrand KC, Wang X, Erkek S, Federation A, Song A, Lee C, Wang X, McDonald L, Morrow JJ, Saiakhova A, Sin-Chan P, ... ... Lupien M, et al. Therapeutic targeting of ependymoma as informed by oncogenic enhancer profiling. Nature. PMID 29258295 DOI: 10.1038/Nature25169 |
0.391 |
|
| 2017 |
Badodi S, Dubuc A, Zhang X, Rosser G, Da Cunha Jaeger M, Kameda-Smith MM, Morrissy AS, Guilhamon P, Suetterlin P, Li XN, Guglielmi L, Merve A, Farooq H, Lupien M, Singh SK, et al. Convergence of BMI1 and CHD7 on ERK Signaling in Medulloblastoma. Cell Reports. 21: 2772-2784. PMID 29212025 DOI: 10.1016/J.Celrep.2017.11.021 |
0.747 |
|
| 2017 |
Dubois-Chevalier J, Mazrooei P, Lupien M, Staels B, Lefebvre P, Eeckhoute J. Organizing combinatorial transcription factor recruitment at cis-regulatory modules. Transcription. 1-15. PMID 29105538 DOI: 10.1080/21541264.2017.1394424 |
0.799 |
|
| 2017 |
Safikhani Z, Smirnov P, Thu KL, Silvester J, El-Hachem N, Quevedo R, Lupien M, Mak TW, Cescon D, Haibe-Kains B. Gene isoforms as expression-based biomarkers predictive of drug response in vitro. Nature Communications. 8: 1126. PMID 29066719 DOI: 10.1038/S41467-017-01153-8 |
0.36 |
|
| 2017 |
Park NI, Guilhamon P, Desai K, McAdam RF, Langille E, O'Connor M, Lan X, Whetstone H, Coutinho FJ, Vanner RJ, Ling E, Prinos P, Lee L, Selvadurai H, Atwal G, ... ... Lupien M, et al. ASCL1 Reorganizes Chromatin to Direct Neuronal Fate and Suppress Tumorigenicity of Glioblastoma Stem Cells. Cell Stem Cell. 21: 411. PMID 28886368 DOI: 10.1016/j.stem.2017.08.008 |
0.78 |
|
| 2017 |
Lan X, Jörg DJ, Cavalli FMG, Richards LM, Nguyen LV, Vanner RJ, Guilhamon P, Lee L, Kushida MM, Pellacani D, Park NI, Coutinho FJ, Whetstone H, Selvadurai HJ, Che C, ... ... Lupien M, et al. Fate mapping of human glioblastoma reveals an invariant stem cell hierarchy. Nature. PMID 28854171 DOI: 10.1038/Nature23666 |
0.795 |
|
| 2017 |
Kron KJ, Murison A, Zhou S, Huang V, Yamaguchi TN, Shiah YJ, Fraser M, van der Kwast T, Boutros PC, Bristow RG, Lupien M. TMPRSS2-ERG fusion co-opts master transcription factors and activates NOTCH signaling in primary prostate cancer. Nature Genetics. PMID 28783165 DOI: 10.1038/Ng.3930 |
0.808 |
|
| 2017 |
Park NI, Guilhamon P, Desai K, McAdam RF, Langille E, O'Connor M, Lan X, Whetstone H, Coutinho FJ, Vanner RJ, Ling E, Prinos P, Lee L, Selvadurai H, Atwal G, ... ... Lupien M, et al. ASCL1 Reorganizes Chromatin to Direct Neuronal Fate and Suppress Tumorigenicity of Glioblastoma Stem Cells. Cell Stem Cell. PMID 28712938 DOI: 10.1016/J.Stem.2017.06.004 |
0.804 |
|
| 2017 |
Dubois-Chevalier J, Dubois V, Dehondt H, Mazrooei P, Mazuy C, Sérandour AA, Gheeraert C, Penderia G, Baugé E, Derudas B, Hennuyer N, Paumelle R, Marot G, Carroll JS, Lupien M, et al. The logic of transcriptional regulator recruitment architecture at cis-regulatory modules controlling liver functions. Genome Research. PMID 28400425 DOI: 10.1101/Gr.217075.116 |
0.799 |
|
| 2017 |
Ahmed M, Sallari RC, Guo H, Moore JH, He HH, Lupien M. Variant Set Enrichment: an R package to identify disease-associated functional genomic regions. Biodata Mining. 10: 9. PMID 28239419 DOI: 10.1186/S13040-017-0129-5 |
0.3 |
|
| 2017 |
Fraser M, Sabelnykova VY, Yamaguchi TN, Heisler LE, Livingstone J, Huang V, Shiah YJ, Yousif F, Lin X, Masella AP, Fox NS, Xie M, Prokopec SD, Berlin A, Lalonde E, ... ... Lupien M, et al. Genomic hallmarks of localized, non-indolent prostate cancer. Nature. PMID 28068672 DOI: 10.1038/Nature20788 |
0.799 |
|
| 2017 |
Joshua AM, Fleshner NE, Chin J, Emmenegger U, Gleave ME, Hotte SJ, Sweet J, Collins C, Boutros PC, Lupien M, Pugh TJ, Chi KN. Abiraterone +/- cabazitaxel in defining complete response in prostatectomy (ACDC-RP) trial. Journal of Clinical Oncology. 35. DOI: 10.1200/Jco.2017.35.15_Suppl.Tps5095 |
0.333 |
|
| 2017 |
Samuel N, Wilson G, Deblois G, Said BI, Fischer NW, Lemire M, Lou Y, Li W, Alexandrova R, Novokmet A, Tran J, Nichols KE, Finlay JL, Choufani S, Remke M, ... ... Lupien M, et al. Abstract NG05: TP53-mediated human cancer susceptibility is defined by epigenetic dysregulation of microRNA-34A Cancer Research. 77. DOI: 10.1158/1538-7445.Am2017-Ng05 |
0.709 |
|
| 2017 |
Ghamrasni SE, Guilhamon P, Quevedo R, Yang C, Lupien M, Pugh T. Abstract 2410: Toward mutation analysis of regulatory elements: Epigenetic profiling of primary breast tumors Cancer Research. 77: 2410-2410. DOI: 10.1158/1538-7445.Am2017-2410 |
0.444 |
|
| 2017 |
Bahr C, von Palekse L, Uslu V, Remeseiro S, Takayama N, Ng S, Murison A, Langenfeld K, Petretich M, Scognamiglio R, Zeisberger P, Benk A, Amit I, Zandstra P, Lupien M, et al. A cluster of enhancer modules directs differential MYC expression along the normal and leukemic haematopoietic stem cell hierarchies Experimental Hematology. 53: S130-S131. DOI: 10.1016/J.Exphem.2017.06.329 |
0.308 |
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| 2016 |
Torchia J, Golbourn B, Feng S, Ho KC, Sin-Chan P, Vasiljevic A, Norman JD, Guilhamon P, Garzia L, Agamez NR, Lu M, Chan TS, Picard D, de Antonellis P, Khuong-Quang DA, ... ... Lupien M, et al. Integrated (epi)-Genomic Analyses Identify Subgroup-Specific Therapeutic Targets in CNS Rhabdoid Tumors. Cancer Cell. 30: 891-908. PMID 27960086 DOI: 10.1016/J.Ccell.2016.11.003 |
0.777 |
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| 2016 |
Zhou S, Treloar AE, Lupien M. Emergence of the Noncoding Cancer Genome: A Target of Genetic and Epigenetic Alterations. Cancer Discovery. 6: 1215-1229. PMID 27807102 DOI: 10.1158/2159-8290.Cd-16-0745 |
0.824 |
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| 2016 |
Bailey SD, Desai K, Kron KJ, Mazrooei P, Sinnott-Armstrong NA, Treloar AE, Dowar M, Thu KL, Cescon DW, Silvester J, Yang SY, Wu X, Pezo RC, Haibe-Kains B, Mak TW, ... ... Lupien M, et al. Noncoding somatic and inherited single-nucleotide variants converge to promote ESR1 expression in breast cancer. Nature Genetics. PMID 27571262 DOI: 10.1038/Ng.3650 |
0.808 |
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| 2016 |
Guo H, Ahmed M, Zhang F, Yao CQ, Li S, Liang Y, Hua J, Soares F, Sun Y, Langstein J, Li Y, Poon C, Bailey SD, Desai K, Fei T, ... ... Lupien M, et al. Modulation of long noncoding RNAs by risk SNPs underlying genetic predispositions to prostate cancer. Nature Genetics. PMID 27526323 DOI: 10.1038/Ng.3637 |
0.82 |
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| 2016 |
Boukhaled GM, Cordeiro B, Deblois G, Dimitrov V, Bailey SD, Holowka T, Domi A, Guak H, Chiu HC, Everts B, Pearce EJ, Lupien M, White JH, Krawczyk CM. The Transcriptional Repressor Polycomb Group Factor 6, PCGF6, Negatively Regulates Dendritic Cell Activation and Promotes Quiescence. Cell Reports. PMID 27498878 DOI: 10.1016/J.Celrep.2016.07.026 |
0.786 |
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| 2016 |
Inoue S, Li WY, Tseng A, Beerman I, Elia AJ, Bendall SC, Lemonnier F, Kron KJ, Cescon DW, Hao Z, Lind EF, Takayama N, Planello AC, Shen SY, Shih AH, ... ... Lupien M, et al. Mutant IDH1 Downregulates ATM and Alters DNA Repair and Sensitivity to DNA Damage Independent of TET2. Cancer Cell. PMID 27424808 DOI: 10.1016/J.Ccell.2016.05.018 |
0.708 |
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| 2016 |
Samuel N, Wilson G, Said BI, Pan A, Deblois G, Fischer NW, Alexandrova R, Casallo G, Paton T, Lupien M, Gariepy J, Merico D, Hudson TJ, Malkin D. Transcriptome-wide characterization of the endogenous miR-34A-p53 tumor suppressor network. Oncotarget. PMID 27391063 DOI: 10.18632/Oncotarget.10417 |
0.688 |
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| 2016 |
Bhat-Nakshatri P, Goswami CP, Badve S, Magnani L, Lupien M, Nakshatri H. Molecular Insights of Pathways Resulting From Two Common PIK3CA Mutations in Breast Cancer. Cancer Research. PMID 27197157 DOI: 10.1158/0008-5472.Can-15-3174 |
0.564 |
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| 2016 |
Malorni L, Giuliano M, Migliaccio I, Wang T, Creighton CJ, Lupien M, Fu X, Hilsenbeck SG, Healy N, De Angelis C, Mazumdar A, Trivedi MV, Massarweh S, Gutierrez C, De Placido S, et al. Blockade of AP-1 Potentiates Endocrine Therapy and Overcomes Resistance. Molecular Cancer Research : McR. PMID 26965145 DOI: 10.1158/1541-7786.Mcr-15-0423 |
0.719 |
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| 2016 |
Planello AC, Singhania R, Kron KJ, Bailey SD, Roulois D, Lupien M, Line SR, de Souza AP, De Carvalho DD. Pre-neoplastic epigenetic disruption of transcriptional enhancers in chronic inflammation. Oncotarget. PMID 26908456 DOI: 10.18632/Oncotarget.7513 |
0.798 |
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| 2016 |
Takayama N, Murison A, Takayanagi S, Zandi S, Penrod N, Mitchel A, Kennedy JA, Ng SW, Xie SZ, Minden MD, Dick JE, Lupien M. Chromatin Accessibility Identifies CTCF As a Gatekeeper of Stemness Functions in Human Hematopoietic Development Blood. 128: 3873-3873. DOI: 10.1182/Blood.V128.22.3873.3873 |
0.385 |
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| 2016 |
Treloar A, Wu X, Penrod N, Bailey SD, Zhang X, Desai K, Gyorffy B, Lupien M. Abstract IA20: Chromatin looping factors and breast cancer Cancer Research. 76. DOI: 10.1158/1538-7445.Fbcr15-Ia20 |
0.734 |
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| 2015 |
Gallo M, Coutinho FJ, Vanner RJ, Gayden T, Mack SC, Murison A, Remke M, Li R, Takayama N, Desai K, Lee L, Lan X, Park NI, Barsyte-Lovejoy D, Smil D, ... ... Lupien M, et al. MLL5 Orchestrates a Cancer Self-Renewal State by Repressing the Histone Variant H3.3 and Globally Reorganizing Chromatin. Cancer Cell. PMID 26626085 DOI: 10.1016/J.Ccell.2015.10.005 |
0.795 |
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| 2015 |
Brunelle M, Nordell Markovits A, Rodrigue S, Lupien M, Jacques PÉ, Gévry N. The histone variant H2A.Z is an important regulator of enhancer activity. Nucleic Acids Research. 43: 9742-56. PMID 26319018 DOI: 10.1093/Nar/Gkv825 |
0.383 |
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| 2015 |
Magnani L, Patten DK, Nguyen VT, Hong SP, Steel JH, Patel N, Lombardo Y, Faronato M, Gomes AR, Woodley L, Page K, Guttery D, Primrose L, Fernandez Garcia D, Shaw J, ... ... Lupien M, et al. The pioneer factor PBX1 is a novel driver of metastatic progression in ERα-positive breast cancer. Oncotarget. PMID 26215677 DOI: 10.18632/Oncotarget.4243 |
0.609 |
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| 2015 |
Bailey SD, Virtanen C, Haibe-Kains B, Lupien M. ABC: a tool to identify SNVs causing allele-specific transcription factor binding from ChIP-Seq experiments. Bioinformatics (Oxford, England). 31: 3057-9. PMID 25995231 DOI: 10.1093/Bioinformatics/Btv321 |
0.704 |
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| 2015 |
Bailey SD, Zhang X, Desai K, Aid M, Corradin O, Cowper-Sal Lari R, Akhtar-Zaidi B, Scacheri PC, Haibe-Kains B, Lupien M. ZNF143 provides sequence specificity to secure chromatin interactions at gene promoters. Nature Communications. 2: 6186. PMID 25645053 DOI: 10.1038/Ncomms7186 |
0.813 |
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| 2015 |
Dingar D, Kalkat M, Chan PK, Srikumar T, Bailey SD, Tu WB, Coyaud E, Ponzielli R, Kolyar M, Jurisica I, Huang A, Lupien M, Penn LZ, Raught B. BioID identifies novel c-MYC interacting partners in cultured cells and xenograft tumors. Journal of Proteomics. 118: 95-111. PMID 25452129 DOI: 10.1016/J.Jprot.2014.09.029 |
0.698 |
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| 2015 |
Dingar D, Kalkat M, Chan P, Bailey SD, Srikumar T, Tu WB, Coyaud E, Ponzielli R, Kolyar M, Jurisica I, Huang A, Lupien M, Raught B, Penn LZ. Abstract B04: In vivo BioID identifies novel Myc interacting partners Molecular Cancer Research. 13. DOI: 10.1158/1557-3125.Myc15-B04 |
0.734 |
|
| 2015 |
Nakshatri H, Goswami C, Badve S, Magnani L, Lupien M, Bhat-Nakshatri P. Abstract P3-05-15: Divergent activation of AKT1 and AKT2 isoforms downstream of PI3K mutation impacts response of breast cancer cells to estradiol and PI3K inhibitors Cancer Research. 75. DOI: 10.1158/1538-7445.Sabcs14-P3-05-15 |
0.586 |
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| 2014 |
Shah MA, Denton EL, Arrowsmith CH, Lupien M, Schapira M. A global assessment of cancer genomic alterations in epigenetic mechanisms. Epigenetics & Chromatin. 7: 29. PMID 25484917 DOI: 10.1186/1756-8935-7-29 |
0.428 |
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| 2014 |
Kron KJ, Bailey SD, Lupien M. Enhancer alterations in cancer: a source for a cell identity crisis. Genome Medicine. 6: 77. PMID 25473436 DOI: 10.1186/S13073-014-0077-3 |
0.824 |
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| 2014 |
Ghoussaini M, Edwards SL, Michailidou K, Nord S, Cowper-Sal Lari R, Desai K, Kar S, Hillman KM, Kaufmann S, Glubb DM, Beesley J, Dennis J, Bolla MK, Wang Q, Dicks E, ... ... Lupien M, et al. Evidence that breast cancer risk at the 2q35 locus is mediated through IGFBP5 regulation. Nature Communications. 4: 4999. PMID 25248036 DOI: 10.1038/Ncomms5999 |
0.807 |
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| 2014 |
Molyneux SD, Waterhouse PD, Shelton D, Shao YW, Watling CM, Tang QL, Harris IS, Dickson BC, Tharmapalan P, Sandve GK, Zhang X, Bailey SD, Berman H, Wunder JS, Izsvák Z, ... ... Lupien M, et al. Human somatic cell mutagenesis creates genetically tractable sarcomas. Nature Genetics. 46: 964-72. PMID 25129143 DOI: 10.1038/Ng.3065 |
0.768 |
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| 2014 |
Brocks D, Assenov Y, Minner S, Bogatyrova O, Simon R, Koop C, Oakes C, Zucknick M, Lipka DB, Weischenfeldt J, Feuerbach L, Cowper-Sal Lari R, Lupien M, Brors B, Korbel J, et al. Intratumor DNA methylation heterogeneity reflects clonal evolution in aggressive prostate cancer. Cell Reports. 8: 798-806. PMID 25066126 DOI: 10.1016/J.Celrep.2014.06.053 |
0.408 |
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| 2014 |
Marcon E, Ni Z, Pu S, Turinsky AL, Trimble SS, Olsen JB, Silverman-Gavrila R, Silverman-Gavrila L, Phanse S, Guo H, Zhong G, Guo X, Young P, Bailey S, Roudeva D, ... ... Lupien M, et al. Human-chromatin-related protein interactions identify a demethylase complex required for chromosome segregation. Cell Reports. 8: 297-310. PMID 24981860 DOI: 10.1016/J.Celrep.2014.05.050 |
0.674 |
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| 2014 |
Chahar S, Gandhi V, Yu S, Desai K, Cowper-Sal-lari R, Kim Y, Perekatt AO, Kumar N, Thackray JK, Musolf A, Kumar N, Hoffman A, Londono D, Vazquez BN, Serrano L, ... ... Lupien M, et al. Chromatin profiling reveals regulatory network shifts and a protective role for hepatocyte nuclear factor 4α during colitis. Molecular and Cellular Biology. 34: 3291-304. PMID 24980432 DOI: 10.1128/Mcb.00349-14 |
0.788 |
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| 2014 |
Antignano F, Burrows K, Hughes MR, Han JM, Kron KJ, Penrod NM, Oudhoff MJ, Wang SK, Min PH, Gold MJ, Chenery AL, Braam MJ, Fung TC, Rossi FM, McNagny KM, ... ... Lupien M, et al. Methyltransferase G9A regulates T cell differentiation during murine intestinal inflammation. The Journal of Clinical Investigation. 124: 1945-55. PMID 24667637 DOI: 10.1172/Jci69592 |
0.711 |
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| 2014 |
Zhang X, Bailey SD, Lupien M. Laying a solid foundation for Manhattan--'setting the functional basis for the post-GWAS era'. Trends in Genetics : Tig. 30: 140-9. PMID 24661571 DOI: 10.1016/J.Tig.2014.02.006 |
0.743 |
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| 2014 |
Gorrini C, Gang BP, Bassi C, Wakeham A, Baniasadi SP, Hao Z, Li WY, Cescon DW, Li YT, Molyneux S, Penrod N, Lupien M, Schmidt EE, Stambolic V, Gauthier ML, et al. Estrogen controls the survival of BRCA1-deficient cells via a PI3K-NRF2-regulated pathway Proceedings of the National Academy of Sciences of the United States of America. 111: 4472-4477. PMID 24567396 DOI: 10.1073/Pnas.1324136111 |
0.401 |
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| 2014 |
Mack SC, Witt H, Piro RM, Gu L, Zuyderduyn S, Stütz AM, Wang X, Gallo M, Garzia L, Zayne K, Zhang X, Ramaswamy V, Jäger N, Jones DT, Sill M, ... ... Lupien M, et al. Epigenomic alterations define lethal CIMP-positive ependymomas of infancy. Nature. 506: 445-50. PMID 24553142 DOI: 10.1038/Nature13108 |
0.712 |
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| 2014 |
Corradin O, Saiakhova A, Akhtar-Zaidi B, Myeroff L, Willis J, Cowper-Sal lari R, Lupien M, Markowitz S, Scacheri PC. Combinatorial effects of multiple enhancer variants in linkage disequilibrium dictate levels of gene expression to confer susceptibility to common traits. Genome Research. 24: 1-13. PMID 24196873 DOI: 10.1101/Gr.164079.113 |
0.382 |
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| 2014 |
Magnani L, Lupien M. Chromatin and epigenetic determinants of estrogen receptor alpha (ESR1) signaling. Molecular and Cellular Endocrinology. 382: 633-41. PMID 23684889 DOI: 10.1016/J.Mce.2013.04.026 |
0.58 |
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| 2014 |
Molyneux SD, Waterhouse PD, Shelton D, Shao YW, Watling CM, Tang Q, Harris IS, Dickson BC, Tharmapalan P, Sandve GK, Zhang X, Bailey SD, Berman H, Wunder JS, Iszvak Z, ... Lupien M, et al. Erratum: Corrigendum: Human somatic cell mutagenesis creates genetically tractable sarcomas Nature Genetics. 46: 1372-1372. DOI: 10.1038/Ng1214-1372 |
0.702 |
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| 2013 |
Forbes NE, Abdelbary H, Lupien M, Bell JC, Diallo JS. Exploiting tumor epigenetics to improve oncolytic virotherapy. Frontiers in Genetics. 4: 184. PMID 24062768 DOI: 10.3389/Fgene.2013.00184 |
0.306 |
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| 2013 |
Magnani L, Stoeck A, Zhang X, Lánczky A, Mirabella AC, Wang TL, Gyorffy B, Lupien M. Genome-wide reprogramming of the chromatin landscape underlies endocrine therapy resistance in breast cancer. Proceedings of the National Academy of Sciences of the United States of America. 110: E1490-9. PMID 23576735 DOI: 10.1073/Pnas.1219992110 |
0.688 |
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| 2012 |
Magnani L, Brunelle M, Gévry N, Lupien M. Chromatin landscape and endocrine response in breast cancer. Epigenomics. 4: 675-83. PMID 23244312 DOI: 10.2217/Epi.12.64 |
0.609 |
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| 2012 |
Cowper-Sal lari R, Zhang X, Wright JB, Bailey SD, Cole MD, Eeckhoute J, Moore JH, Lupien M. Breast cancer risk-associated SNPs modulate the affinity of chromatin for FOXA1 and alter gene expression. Nature Genetics. 44: 1191-8. PMID 23001124 DOI: 10.1038/Ng.2416 |
0.817 |
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| 2012 |
Urbach D, Lupien M, Karagas MR, Moore JH. Cancer heterogeneity: origins and implications for genetic association studies. Trends in Genetics : Tig. 28: 538-43. PMID 22858414 DOI: 10.1016/J.Tig.2012.07.001 |
0.328 |
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| 2012 |
Zhang X, Cowper-Sal lari R, Bailey SD, Moore JH, Lupien M. Integrative functional genomics identifies an enhancer looping to the SOX9 gene disrupted by the 17q24.3 prostate cancer risk locus. Genome Research. 22: 1437-46. PMID 22665440 DOI: 10.1101/Gr.135665.111 |
0.758 |
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| 2012 |
Thiaville MM, Stoeck A, Chen L, Wu RC, Magnani L, Oidtman J, Shih IeM, Lupien M, Wang TL. Identification of PBX1 target genes in cancer cells by global mapping of PBX1 binding sites. Plos One. 7: e36054. PMID 22567123 DOI: 10.1371/Journal.Pone.0036054 |
0.629 |
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| 2012 |
Akhtar-Zaidi B, Cowper-Sal-lari R, Corradin O, Saiakhova A, Bartels CF, Balasubramanian D, Myeroff L, Lutterbaugh J, Jarrar A, Kalady MF, Willis J, Moore JH, Tesar PJ, Laframboise T, Markowitz S, ... Lupien M, et al. Epigenomic enhancer profiling defines a signature of colon cancer. Science (New York, N.Y.). 336: 736-9. PMID 22499810 DOI: 10.1126/Science.1217277 |
0.452 |
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| 2011 |
Magnani L, Ballantyne EB, Zhang X, Lupien M. PBX1 genomic pioneer function drives ERα signaling underlying progression in breast cancer. Plos Genetics. 7: e1002368. PMID 22125492 DOI: 10.1371/Journal.Pgen.1002368 |
0.706 |
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| 2011 |
Tang Q, Chen Y, Meyer C, Geistlinger T, Lupien M, Wang Q, Liu T, Zhang Y, Brown M, Liu XS. A comprehensive view of nuclear receptor cancer cistromes. Cancer Research. 71: 6940-7. PMID 21940749 DOI: 10.1158/0008-5472.Can-11-2091 |
0.577 |
|
| 2011 |
Magnani L, Eeckhoute J, Lupien M. Pioneer factors: directing transcriptional regulators within the chromatin environment. Trends in Genetics : Tig. 27: 465-74. PMID 21885149 DOI: 10.1016/J.Tig.2011.07.002 |
0.745 |
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| 2011 |
Sérandour AA, Avner S, Percevault F, Demay F, Bizot M, Lucchetti-Miganeh C, Barloy-Hubler F, Brown M, Lupien M, Métivier R, Salbert G, Eeckhoute J. Epigenetic switch involved in activation of pioneer factor FOXA1-dependent enhancers. Genome Research. 21: 555-65. PMID 21233399 DOI: 10.1101/Gr.111534.110 |
0.758 |
|
| 2011 |
Cowper-Sal lari R, Cole MD, Karagas MR, Lupien M, Moore JH. Layers of epistasis: genome-wide regulatory networks and network approaches to genome-wide association studies. Wiley Interdisciplinary Reviews. Systems Biology and Medicine. 3: 513-26. PMID 21197657 DOI: 10.1002/Wsbm.132 |
0.315 |
|
| 2011 |
Madak-Erdogan Z, Lupien M, Stossi F, Brown M, Katzenellenbogen BS. Genomic collaboration of estrogen receptor alpha and extracellular signal-regulated kinase 2 in regulating gene and proliferation programs. Molecular and Cellular Biology. 31: 226-36. PMID 20956553 DOI: 10.1128/Mcb.00821-10 |
0.576 |
|
| 2011 |
Malorni L, Giuliano M, Migliaccio I, Wang T, Creighton C, Lupien M, Hilsenbeck S, Healy N, Mazumdar A, Trivedi M, Jeselsohn R, He H, Fu X, Gutierrez C, Brown M, et al. P4-01-18: AP-1 Blockade Potentiates the Anti-Tumor Effect of Endocrine Treatment and Reverts the Resistant Phenotype in Hormone Receptor-Positive Breast Cancer. Cancer Research. 71. DOI: 10.1158/0008-5472.Sabcs11-P4-01-18 |
0.708 |
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| 2010 |
Lupien M, Meyer CA, Bailey ST, Eeckhoute J, Cook J, Westerling T, Zhang X, Carroll JS, Rhodes DR, Liu XS, Brown M. Growth factor stimulation induces a distinct ER(alpha) cistrome underlying breast cancer endocrine resistance. Genes & Development. 24: 2219-27. PMID 20889718 DOI: 10.1101/Gad.1944810 |
0.812 |
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| 2010 |
He HH, Meyer CA, Shin H, Bailey ST, Wei G, Wang Q, Zhang Y, Xu K, Ni M, Lupien M, Mieczkowski P, Lieb JD, Zhao K, Brown M, Liu XS. Nucleosome dynamics define transcriptional enhancers. Nature Genetics. 42: 343-7. PMID 20208536 DOI: 10.1038/Ng.545 |
0.607 |
|
| 2010 |
Wolfer A, Wittner BS, Irimia D, Flavin RJ, Lupien M, Gunawardane RN, Meyer CA, Lightcap ES, Tamayo P, Mesirov JP, Liu XS, Shioda T, Toner M, Loda M, Brown M, et al. MYC regulation of a "poor-prognosis" metastatic cancer cell state. Proceedings of the National Academy of Sciences of the United States of America. 107: 3698-703. PMID 20133671 DOI: 10.1073/Pnas.0914203107 |
0.599 |
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| 2010 |
Wade HE, Kobayashi S, Eaton ML, Jansen MS, Lobenhofer EK, Lupien M, Geistlinger TR, Zhu W, Nevins JR, Brown M, Otteson DC, McDonnell DP. Multimodal regulation of E2F1 gene expression by progestins. Molecular and Cellular Biology. 30: 1866-77. PMID 20123965 DOI: 10.1128/Mcb.01060-09 |
0.591 |
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| 2010 |
Wolfer A, Wittner BS, Irimia D, Flavin RJ, Lupien M, Gunawardane RN, Meyer CA, Lightcap ES, Tamayo P, Mesirov JP, Liu XS, Shioda T, Toner M, Loda M, Brown M, et al. Abstract 3300: MYC regulation of a “poor prognosis” metastatic cancer cell state Cancer Research. 70: 3300-3300. DOI: 10.1158/1538-7445.Am10-3300 |
0.606 |
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| 2009 |
Boros J, Donaldson IJ, O'Donnell A, Odrowaz ZA, Zeef L, Lupien M, Meyer CA, Liu XS, Brown M, Sharrocks AD. Elucidation of the ELK1 target gene network reveals a role in the coordinate regulation of core components of the gene regulation machinery. Genome Research. 19: 1963-73. PMID 19687146 DOI: 10.1101/Gr.093047.109 |
0.557 |
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| 2009 |
Wang Q, Li W, Zhang Y, Yuan X, Xu K, Yu J, Chen Z, Beroukhim R, Wang H, Lupien M, Wu T, Regan MM, Meyer CA, Carroll JS, Manrai AK, et al. Androgen receptor regulates a distinct transcription program in androgen-independent prostate cancer. Cell. 138: 245-56. PMID 19632176 DOI: 10.1016/J.Cell.2009.04.056 |
0.717 |
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| 2009 |
Eeckhoute J, Lupien M, Brown M. Combining chromatin immunoprecipitation and oligonucleotide tiling arrays (ChIP-Chip) for functional genomic studies. Methods in Molecular Biology (Clifton, N.J.). 556: 155-64. PMID 19488877 DOI: 10.1007/978-1-60327-192-9_11 |
0.728 |
|
| 2009 |
Lupien M, Brown M. Cistromics of hormone-dependent cancer. Endocrine-Related Cancer. 16: 381-9. PMID 19369485 DOI: 10.1677/Erc-09-0038 |
0.662 |
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| 2009 |
Lupien M, Eeckhoute J, Meyer CA, Krum SA, Rhodes DR, Liu XS, Brown M. Coactivator function defines the active estrogen receptor alpha cistrome. Molecular and Cellular Biology. 29: 3413-23. PMID 19364822 DOI: 10.1128/Mcb.00020-09 |
0.734 |
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| 2009 |
Eeckhoute J, Lupien M, Meyer CA, Verzi MP, Shivdasani RA, Liu XS, Brown M. Cell-type selective chromatin remodeling defines the active subset of FOXA1-bound enhancers. Genome Research. 19: 372-80. PMID 19129543 DOI: 10.1101/Gr.084582.108 |
0.743 |
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| 2008 |
Krum SA, Miranda-Carboni GA, Lupien M, Eeckhoute J, Carroll JS, Brown M. Unique ERalpha cistromes control cell type-specific gene regulation. Molecular Endocrinology (Baltimore, Md.). 22: 2393-406. PMID 18818283 DOI: 10.1210/Me.2008-0100 |
0.793 |
|
| 2008 |
Setlur SR, Mertz KD, Hoshida Y, Demichelis F, Lupien M, Perner S, Sboner A, Pawitan Y, Andrén O, Johnson LA, Tang J, Adami HO, Calza S, Chinnaiyan AM, Rhodes D, et al. Estrogen-dependent signaling in a molecularly distinct subclass of aggressive prostate cancer. Journal of the National Cancer Institute. 100: 815-25. PMID 18505969 DOI: 10.1093/Jnci/Djn150 |
0.585 |
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| 2008 |
Lupien M, Eeckhoute J, Meyer CA, Wang Q, Zhang Y, Li W, Carroll JS, Liu XS, Brown M. FoxA1 translates epigenetic signatures into enhancer-driven lineage-specific transcription. Cell. 132: 958-70. PMID 18358809 DOI: 10.1016/J.Cell.2008.01.018 |
0.793 |
|
| 2008 |
Frietze S, Lupien M, Silver PA, Brown M. CARM1 regulates estrogen-stimulated breast cancer growth through up-regulation of E2F1. Cancer Research. 68: 301-6. PMID 18172323 DOI: 10.1158/0008-5472.Can-07-1983 |
0.596 |
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| 2007 |
Eeckhoute J, Keeton EK, Lupien M, Krum SA, Carroll JS, Brown M. Positive cross-regulatory loop ties GATA-3 to estrogen receptor alpha expression in breast cancer. Cancer Research. 67: 6477-83. PMID 17616709 DOI: 10.1158/0008-5472.Can-07-0746 |
0.778 |
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| 2007 |
Lupien M, Jeyakumar M, Hébert E, Hilmi K, Cotnoir-White D, Loch C, Auger A, Dayan G, Pinard GA, Wurtz JM, Moras D, Katzenellenbogen J, Mader S. Raloxifene and ICI182,780 increase estrogen receptor-alpha association with a nuclear compartment via overlapping sets of hydrophobic amino acids in activation function 2 helix 12. Molecular Endocrinology (Baltimore, Md.). 21: 797-816. PMID 17299137 DOI: 10.1210/Me.2006-0074 |
0.793 |
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| 2006 |
Lupien M, Diévart A, Morales CR, Hermo L, Calvo E, Kay DG, Hu C, Jolicoeur P. Expression of constitutively active Notch1 in male genital tracts results in ectopic growth and blockage of efferent ducts, epididymal hyperplasia and sterility. Developmental Biology. 300: 497-511. PMID 17046738 DOI: 10.1016/J.Ydbio.2006.09.010 |
0.302 |
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| 2006 |
Dayan G, Lupien M, Auger A, Anghel SI, Rocha W, Croisetière S, Katzenellenbogen JA, Mader S. Tamoxifen and raloxifene differ in their functional interactions with aspartate 351 of estrogen receptor alpha. Molecular Pharmacology. 70: 579-88. PMID 16679488 DOI: 10.1124/Mol.105.021931 |
0.546 |
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| 2006 |
Hu C, Diévart A, Lupien M, Calvo E, Tremblay G, Jolicoeur P. Overexpression of activated murine Notch1 and Notch3 in transgenic mice blocks mammary gland development and induces mammary tumors. The American Journal of Pathology. 168: 973-90. PMID 16507912 DOI: 10.2353/Ajpath.2006.050416 |
0.314 |
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